Cinacalcet

Molecule Description

Cinacalcet is utilized in the treatment of Hypercalcemia(high levels of calcium

in the blood) and Hyperparathyroidism(high levels of parathyroid hormone in the blood).

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Cinacalcet

The treatment of high levels of calcium in the blood
The treatment of high levels of parathyroid hormone in the blood due to parathyroid cancer or primary Hyperparathyroidism
Treatment of secondary Hyperparathyroidism (HPT) in individuals with End Stage Renal Disease (ESRD) on maintenance dialysis therapy

Contraindications of Cinacalcet

When should one not use Cinacalcet

Do not take if you are allergic to Cinacalcet or any ingredient of this medicine
Do not take if you have low calcium levels in blood

Side effects of Cinacalcet

Common side effects of this drug are:

Nausea and vomiting
Allergic symptoms - itching, hives, rash, swelling of lips, face, throat, etc.
Muscle pain, tightness
Convulsion
Numbness around the mouth
Shortness of breath, rapid weight gain

Precautions and Warnings of Cinacalcet

Pregnancy

Can I take Cinacalcet during pregnancy?

It is probably unsafe to use this medicine during pregnancy.

Breast Feeding

Can I take Cinacalcet while breastfeeding?

It is probably unsafe to use this medicine during breastfeeding.

Driving

Can I drive if I have consumed Cinacalcet?

This medicine may decrease your alertness. Do not drive unless you feel well.

Alcohol

Can I consume alcohol with Cinacalcet?

You must avoid too much intake of alcohol.

Other General Warnings

Talk to your doctor if

In case you are taking treatment for high levels of parathyroid hormone in blood
Your calcium levels are not monitored before beginning the treatment with this medicine and during the treatment with this medicine
You feel any signs of low calcium level
You have kidney disease, heart disease
Person with severe kidney disease who are not on dialysis

Mode of Action of Cinacalcet

How Does It Work?

Cinacalcet mimics calcium, thereby reducing the levels of parathyroid hormone, which in turn decreases the levels of calcium in the blood.

Interactions of Cinacalcet

Interactions with other medicines

This medicine has significant interactions with Atomoxetine, Brexpiprazole, Eliglustat, Tamoxifen, Iloperidone, Thioridazine, Pimozide, Vortioxetine, and Tetrabenazine and minor to moderate interactio...
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A patient may require to adjust the dosage of Cinacalcet if he/she initiates or discontinues the therapy with a strong inhibitor (e.g., Ketoconazole, Itraconazole, Telithromycin, Voriconazole, Ritonav...
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Interactions with food items

No information is available on interaction of Cinacalcet when taken with food, consult your doctor or pharmacist for details.

Dietary Restrictions of Cinacalcet

No information is available on dietary restrictions while you are taking Cinacalcet, consult your doctor or pharmacist for further details.

Dosage of Cinacalcet

Overdose

The effects of an overdose may be lethal and needs immediate medical attention
The symptoms of overdose can be – nausea, vomiting, etc. If you happen to take an overdose of the medicine, kindly seek emergency medical care immediately

Missed a Dose

Do not take a double dose if you have missed a dose; take the next dose as soon as you remember.

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare provider before taking Cinacalcet?

Inform the doctor about your detailed medical, surgical and allergy history
Inform your physician if you have any of the following conditions:
Liver disease
Kidney disease
Heart disease
Low calcium levels in blood
High or low BP
History of seizures
Inform the doctor if you are pregnant, lactating, or planning a pregnancy

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Medicines containing Cinacalcet

PTH 30MG STRIP OF 10 TABLETS

By INTAS PHARMACEUTICALS LTD

10 Tablet(s) in Strip

₹755.22*

MRP ₹888.50

15% OFF

CERACAL 30MG TABLET

By BIOCON LTD

10 Tablet(s) in Strip

Price to be Updated

Out of Stock

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