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molecule

Amphotericin B

Molecule Description

Amphotericin B is an antifungal medicine. It is used for the treatment of serio

us fungal infections, kala-azar, and fungal infections of the skin. Amphotericin works by slowing down the growth of fungus and helps in preventing the spread of infection. It comes as an injection, gel, and drops.

uses

Uses of Amphotericin B

  • Serious fungal infections
  • Kala azar (visceral leishmaniasis)
  • Fungal infection of skin
contraindications

Contraindications of Amphotericin B

When should one not use Amphotericin B

Known allergy to amphotericin B.
sideEffects

Side effects of Amphotericin B

Common side effects of this drug are:

  • Headache
  • Vomiting
  • Nausea
  • Fever
  • Chills
  • Rashes
  • Itching
  • Decrease in serum potassium levels
  • Pain or swelling at the injection site
precautionsAndWarnings

Precautions and Warnings of Amphotericin B

pregnancy

Pregnancy

Q:
Can I take amphotericin B during pregnancy?
A:
There is limited safety information available about use of amphotericin B in pregnant women. Consult your doctor for advice.
breastfeeding

Breast Feeding

Q:
Can I take amphotericin B while breastfeeding?
A:
It is not known if amphotericin B passes in breastmilk. Consult your doctor before taking this medicine if you are a lactating woman.
driving

Driving

Q:
Can I drive if I am taking amphotericin B?
A:
Amphotericin B does not affect your ability to drive.
alcohol

Alcohol

Q:
Can I consume alcohol with amphotericin B?
A:
Although the interaction of amphotericin B with alcohol is not known, it is advisable to consult your doctor if you drink too often.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You have a liver or kidney-related disorder.
  • You experience skin allergy and rashes after taking this medicine.
  • Amphotericin B must not be used for superficial fungal infections.
  • When on treatment with amphotericin B, your doctor may ask you to perform blood tests to monitor your potassium, magnesium levels and kidney function.
modeOfAction

Mode of Action of Amphotericin B

How Does It Work?

Amphotericin B binds to the fungal cells and makes them more porous that leads to the leakage of cell components and fungal cell death.
interactions

Interactions of Amphotericin B

Interactions with other medicines

Certain medicines can affect the way amphotericin B works or amphotericin B itself can alter the action of other medicines taken at the same time. Hence, it is important to inform your doctor about al...
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Content Details

WRITTEN BY
doctor

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: What should I discuss with my healthcare provider before taking amphotericin B?

  • Inform the doctor about your detailed medical and surgical history.
  • Inform your physician if you have any of the following conditions such as heart disease, kidney disease, liver disease, diabetes, electrolyte imbalance.
  • If you have received blood transfusions, are receiving any radiation treatment or cancer medications, are pregnant, breastfeeding or planning a pregnancy.

Q: How is amphotericin B used?

A: The commonly used route is IV (intravenous) given by doctor or nurse into the vein over 30- 60 minutes period in drip infusion. It is given after the test dose to check for allergy. If no allergic reactions develop, the doctor or nurse will continue the injection. Topically amphotericin B is used as gel or drops.
Last Updated on: 25 Aug 2021 | 07:58 PM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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