Signoflam Strip Of 10 Tablets
Description
Signoflam Tablet is a widely used medicine for relieving pain, swelling, and inflammation affecting the muscles, joints, and bones. It is commonly prescribed for conditions like arthritis, spondylitis, sports injuries, and post-surgical pain. Addressing the root cause of pain and inflammation helps patients move more comfortably and improves daily functioning.
This tablet contains a potent combination of Aceclofenac, Paracetamol, and Serratiopeptidase. Aceclofenac and Paracetamol work together to block specific natural substances (prostaglandins) that cause pain and inflammation. Serratiopeptidase helps reduce swelling by breaking down proteins responsible for inflammation, supporting faster healing of damaged tissues. Together, these ingredients offer effective relief and promote recovery.
Signoflam Tablet should be taken strictly as prescribed by your doctor. It is usually advised to be taken with food to prevent stomach upset. Take the medicine at the same time each day for the best results. Avoid skipping doses and do not exceed the prescribed amount, as overuse may lead to unwanted side effects.
Like all medicines, Signoflam may cause side effects such as nausea, dizziness, stomach discomfort, or diarrhoea in some individuals. These effects are generally temporary, but consult your doctor if they persist or worsen. Avoid alcohol while taking this medicine, as it may increase the risk of liver or stomach problems. Patients with a history of kidney, liver, or heart conditions should use this medication with caution.
Other medicines containing the same combination of Aceclofenac, Paracetamol, and Serratiopeptidase include Zerodol Sp tablet, Movexx Sp tablet, Aceclotrue Sp tablet, Acemiz S tablet, and Aldigesic Sp tablet. However, Signoflam Tablet remains a trusted choice for effective relief from pain, swelling, and inflammation.
Product Summary
Offer Price | ₹115.41 |
You Save | ₹42.69 (27% on MRP) |
Contains | Aceclofenac(100.0 Mg)+Serratiopeptidase(15.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg) |
Uses | Joints and muscular pain |
Side effects | Nausea, vomiting, dizziness, indigestion, stomach pain |
Therapy | ANALGESIC/ANTIPYRETIC |
- Movexx Sp Strip Of 10 TabletsBy Cipla Gx10 Tablet(s) in StripMRP 127.77₹ 88.1630% CHEAPER₹ 8.82/Tablet
- Aceclotrue Sp Strip Of 10 TabletsBy Avighna Medicare Pvt Ltd10 Tablet(s) in StripMRP 105.73₹ 77.1840% CHEAPER₹ 7.72/Tablet
- Alcinac Forte Strip Of 10 TabletsBy Leeford Healthcare Ltd10 Tablet(s) in StripMRP 85.00₹ 60.3553% CHEAPER₹ 6.04/Tablet
- Acemiz S Strip Of 10 TabletsBy Lupin10 Tablet(s) in StripMRP 139.65₹ 76.8136% CHEAPER₹ 7.68/Tablet
- Enzoflam Sp Strip Of 10 TabletsBy Alkem Laboratories Ltd10 Tablet(s) in StripMRP 133.00₹ 109.0617% CHEAPER₹ 10.91/Tablet
- Hifenac Sp Strip Of 10 TabletsBy Intas Pharmaceuticals Ltd10 Tablet(s) in StripMRP 133.75₹ 109.6816% CHEAPER₹ 10.97/Tablet
- Hifenac D Strip Of 10 TabletsBy Intas Pharmaceuticals Ltd10 Tablet(s) in StripMRP 133.75₹ 102.9920% CHEAPER₹ 10.30/Tablet
- Acecloren Strip Of 10 TabletsBy Indoco Remedies Ltd10 Tablet(s) in StripMRP 132.80₹ 99.6023% CHEAPER₹ 9.96/Tablet
- Acenac Sp Strip Of 10 TabletsBy Medley Pharmaceuticals Ltd10 Tablet(s) in StripMRP 132.50₹ 107.3318% CHEAPER₹ 10.73/Tablet
- Aceclo Sera Strip Of 10 TabletsBy Aristo Pharmaceuticals Pvt Ltd10 Tablet(s) in StripMRP 125.00₹ 101.2523% CHEAPER₹ 10.13/Tablet
Uses
Contraindications
- If you have an allergy to Paracetamol, Aceclofenac, Serratiopeptidase or any of the ingredients of this medicine.
- If you have a history of allergies, including asthma, skin rashes or runny nose after taking medicines like Ibuprofen and Aspirin.
- If you have ever experienced severe allergic reactions.
- If you have a history of frequent stomach ulcers or bleeding.
- If you are suffering from any heart disease like heart failure and high blood pressure.
- If you have problems with kidney and liver function.
- If you are pregnant (especially after 3rd month of pregnancy).
Side effects
- Nausea
- Vomiting
- Dizziness
- Indigestion
- Stomach pain
- Constipation
- Diarrhoea
- Bloating
- Stomach ulcers
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have kidney or liver problems.
- You have heart problems like high blood pressure and heart failure.
- If you are an elderly patient taking diuretics or have kidney disorders, then this medicine can increase the risk of kidney failure. Your doctor may ask you to do renal function tests for the same.
- You are suffering from gastrointestinal problems like bleeding, ulcers in the intestine (perforation) or Crohn's disease, or you notice black tarry stools.
- You have asthma, and this medicine can worsen the same.
- You have SLE (autoimmune disorder).
- You are an alcoholic, and the concomitant use of this medicine can damage the liver.
- You have disorders related to blood, like clotting problems and anaemia.
- You have skin rashes & lesions after taking this medicine.
Directions for Use
Storage and disposal
- Store in a cool and dry place protected from moisture.
- Keep it out of reach of children.
Quick Tips
- Signoflam tablet reduces pain and swelling due to bone and soft tissue injury and post-operative swelling, redness and pain. It should not be used for treating any condition other than that specified by your doctor....
- Do not take more than the daily prescribed dose of this medicine, as it may affect the liver or cause allergic reactions.
- You should inform your doctor if you have experienced asthma, rhinitis, swelling of the face/lips/tongue or hives after taking aspirin or other NSAIDs in the past.
- Before taking this medicine, inform your doctor if you are pregnant, planning on getting pregnant or breastfeeding. Also, inform your doctor about all your medications and medical history.
- Nausea, vomiting, diarrhoea and abdominal pain can be side effects of this medicine in some individuals. If side effects bother you, please inform your doctor.
- Do not take any other paracetamol-containing products while taking Signoflam tablet. Tell your doctor if you have a history or have an alcohol addiction.
Dosage
Overdose
Missed a Dose
- If you have missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one....
Mode of Action
How Does It Work?
- This combination acts by interfering with the production of a chemical called prostaglandin which is responsible for swelling and pain.
- It also promotes cartilage matrix synthesis, tissue repair and decreases swelling.
Interactions
Interactions with other medicines
- Do not take any other medicines containing Paracetamol or Aceclofenac, as there is a risk of liver damage.
- If you are taking medicines for high blood pressure, this medicine can interfere with their effect.
- Medicines like water pills can lead to kidney damage when taken along with it.
- Caution is needed if you are taking medicines to treat heart failure.
- This medicine can increase the levels of lithium and methotrexate.
- Medicines used to modify immune responses during organ transplants, like ciclosporin & tacrolimus, can result in kidney damage if taken with this medicine.
- Increased risk of stomach ulcers or bleeding when taken with steroids or other pain relief medicines like Aspirin.
- There is a risk of bleeding if you are taking blood-thinning medicines like Warfarin and Coumarin.
- Increased risk of fits if you are taking this medicine with antibiotics like Levofloxacin and Ciprofloxacin.
- If you are taking medicines to treat diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat and hunger pang.
- Medicines used to treat fits, seizures & depression include Phenobarbital, Carbamazepine, Phenytoin and Clonazepam.
- Medicine used to treat gout like Probenecid.
- Medicines used to treat bacterial infections like Chloramphenicol and rifampicin and HIV infections like Zidovudine.
Interactions with food items
Content Details

Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Being a diabetic, do I need to take precautions before taking this medicine?
Q: Can I take my regular painkillers along with Signoflam?
Q: I have been on Signoflam for a long time, do I need to conduct any tests?
Q: Is Signoflam an antibiotic medicine?
Q: What are the side effects of Signoflam tablets?
Q: Can I take Signoflam for period pain?
Q: Can I take Signoflam for a toothache?
Q: How do Signoflam tablets work?
Q: Can Signoflam be used for fever?
Q: When should you eat Signoflam?
Q: How many Signoflam can be taken in a day?
Q: What is the composition of Signoflam?
Q: What is Signoflam used for?
Q: Can Signoflam be taken during pregnancy?
Q: How to take Signoflam?
Q: Can Signoflam be used for headaches?
Q: Is Signoflam a painkiller?
Q: Signoflam vs Acemiz-S, are they the same?
Q: Signoflam vs Combiflam, what are the differences?
Q: Signoflam vs Enzoflam, are they the same?
Q: Signoflam vs Zerodol SP, are they the same?
References
- VOLTANEC SP-CiplaMed. 2022 [cited 10 August 2022]
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 10 August 2022]
- Aceclofenac+Paracetamol+Serratiopeptidase- NCBI [Internet]. Ncbi.nlm.nih.gov. 2022 [cited 10 August 2022]
- National Center for Biotechnology Information (NCBI). Aceclofenac [Internet]. PubChem Compound Database; 2024 [cited 31 December 2024].
- DrugBank. Aceclofenac. DrugBank; 2024 [cited 31 December 2024].
- Drugs.com. Paracetamol [Internet]. 2024 [cited 31 December 2024]
- ScienceDirect. Paracetamol [Internet]. 2024 [cited 31 December 2024].
Did you find this medicine information helpful?
Please rate your experience