Signoflam tablet is used to relieve pain and inflammation of muscles, joints and bones in conditions such as arthritis, spondylitis and injuries. It is also used after operations and surgeries for relieving pain, inflammation and swelling. Signoflam tablet contains a combination of three medicines, namely Aceclofenac, Paracetamol and Serratiopeptidase. It should be taken as directed by the doctor and in doses and duration as prescribed....
Precautions and Warnings
Mode of Action
Directions for Use
Storage and disposal
Uses of Signoflam Tablet
Signoflam tablet is used to for relieving pain and inflammation of muscles, joints and bones in conditions such as arthritis, spondylitis and injuries. It is also used after operations and surgeries for relieving pain, inflammation and swelling....
Contraindications of Signoflam Tablet
If you have an allergy to Paracetamol, Aceclofenac, Serratiopeptidase or any of the ingredient of this medicine
If you have a history of allergy including asthma, skin rashes or runny nose after taking medicines like Ibuprofen and Aspirin
If you have ever experienced severe allergic reactions
If you have a history of frequent stomach ulcers or bleeding
If you are suffering from any heart disease like heart failure and high blood pressure
If you have problems with kidney and liver function
If you are pregnant (especially after 3rd month of pregnancy)
Side effects of Signoflam Tablet
Precautions and Warnings of Signoflam Tablet
Can I take Signoflam Tablet during pregnancy?
It is unsafe to take this medicine during pregnancy. Hence it should not be taken by pregnant women. Taking this medicine in pregnancy can cause defects in the baby's heart or even delay of delivery or increase the risk of bleeding.
Can I take Signoflam Tablet while breastfeeding?
It is advised not to use this medicine if you are breastfeeding.
Can I drive if I have consumed Signoflam Tablet?
It is advised not to drive or use machines when you have taken this medicine as it may cause dizziness.
Can I consume alcohol with Signoflam Tablet?
It is advisable to avoid the consumption of alcohol during the treatment as it may worsen your liver problems and other side effects.
Other General Warnings
Talk to your doctor if
You have kidney or liver problems
You have heart problems like high blood pressure, heart failure
You are an elderly patient or taking diuretics or have kidney disorder, then this medicine can increase the risk of kidney failure. Your doctor may ask you to do renal function tests for the same
You are suffering from gastrointestinal problems like bleeding, ulcers in the intestine (perforation) or Crohn's disease or you notice black tarry stools
You have asthma as this medicine can worsen the same
You have SLE (autoimmune disorder)
You are an alcoholic and concomitant use of this medicine can damage the liver
You have disorders related to blood like clotting problems and anemia
You have skin rashes & lesions after taking this medicine
Mode of Action of Signoflam Tablet
How Does It Work?
This combination acts by interfering with the production of a chemical called prostaglandin which is responsible for swelling and pain
It also promotes cartilage matrix synthesis, tissue repair and decreases swelling
Directions for Use of Signoflam Tablet
This medicine should be consumed as a whole with a sufficient amount of water and can be taken after food.
Interactions of Signoflam Tablet
Interactions with other medicines
Do not take any other medicines containing Paracetamol or Acelofenac as there is a risk of liver damage
If you are taking medicines for high blood pressure, this medicine can interfere with their effect
Medicines like water pill can lead to kidney damage when taken along with it
Caution is needed if you are taking medicines to treat heart failure
This medicine can increase the levels of lithium and methotrexate
Medicines used to modify immune response during organ transplant like ciclosporin & tacrolimus can result in kidney damage if taken with this medicine
Increased risk of stomach ulcers or bleeding when taken with steroids or other pain relief medicines like Aspirin
There is a risk of bleeding if you are taking blood-thinning medicines like Warfarin and Coumarin
Increased risk of fits if you are taking this medicine with antibiotics like Levofloxacin and Ciprofloxacin
If you are taking medicines to treat diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat and hunger pangs
Medicines used to treat fits, seizures & depression-like Phenobarbital, Carbamazepine, Phenytoin and Clonazepam
Medicine used to treat gout like Probenecid
Medicines used to treat bacterial infection like Chloramphenicol, Rifampicin and HIV infections like Zidovudine
Storage and disposal of Signoflam Tablet
Store in a cool and dry place protected from moisture
Keep it out of reach of children
Dosage of Signoflam Tablet
Taking Signoflam Tablet in high doses may result in symptoms of overdose like headache, nausea, vomiting and stomach pain. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital....
Missed a Dose
If you have missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one...
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