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Xl 80 Tablet

10 Tablet(s) in Strip
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Xl 80 Tablet Description

Xl 80 tablet is a combination medication of two active ingredients, codeine and chlorpheniramine. Codeine belongs to the group of medicines known as opiates and is a derivative of morphine. It is pri

marily used to treat pain, cough and diarrhoea. Chlorpheniramine maleate belongs to a group of medicines known as antihistamines which are anti-allergic and help treat allergies like runny nose, common cold and itchy eyes. Together in combination, they treat cough and common cold along with other allergies. Xl 80 tablet also facilitates decongesting the nasal pathways. Xl Tablet is to be taken orally with water, with/without meals as prescribed by your physician. It can cause side effects like dizziness, confusion, nausea and blurry vision. It is not approved for anyone below 12.


Product Summary

Offer Price₹99.44
You Save₹13.56 (12% on MRP)
ContainsTriprolidine(1.25 Mg) + Codeine(8.0 Mg)
UsesDry cough, allergic congestion, common cold, runny nose, itchy eyes.
Side effectsDizziness, headaches, nausea, constipation, confusion, tiredness.
Check more medicines with composition as Triprolidine(1.25 Mg) + Codeine(8.0 Mg)

Uses of Xl 80 Tablet

  • Dry cough caused due to allergy
  • Allergies like runny nose, itchy eyes
  • Common cold due to seasonal allergies
  • Congested nasal pathways.

Contraindications of Xl 80 Tablet

  • Allergy to codeine or chlorpheniramine
  • Respiratory problems
  • Children below 12 years
  • Paralytic ileus ( paralysis of the small intestine)
  • Intestinal obstructions / blockage
  • Heart ailments
  • High blood pressure
  • Diabetes
  • Glaucoma (increased eye pressure due to intra eye defects)
  • Ulcers
  • Seizures
  • Enlarged prostate gland
  • Hyperthyroid (overactive thyroid)
  • Physically challenged elderly patients

Side effects of Xl 80 Tablet

  • Headaches
  • Confusion
  • Dizziness
  • Tiredness
  • Constipation

Precautions and Warnings of Xl 80 Tablet



Can I take Xl 80 tablet during pregnancy?
No, studies have shown potential harm to the foetus when this combination is taken during pregnancy. Consult your physician if you are pregnant or planning a pregnancy while on this medication.

Breast Feeding

Can I take Xl 80 tablet while breastfeeding?
No, the codeine content of the medicine can pass via breast milk from mother to child and cause opiate toxicity. (Effects the cerebellum of the brain in small children). Symptoms include yawning, sweating, drainage from the nose and eyes. It can be fatal if not managed early.


Can I drive if I have taken Xl 80 tablet?
It is not recommended to drive or operate any kind of heavy machinery while on Xl 80 tablets as it can cause side effects like dizziness, headaches and lightheadedness.


Can I consume alcohol with the Xl 80 tablet?
No, alcohol consumption is prohibited while on this medicine as it may increase the severity of side effects like dizziness, nausea, headaches and constipation.

Other General Warnings

Talk to your doctor if
  • Your side effects are persistent and seem to worsen over time.
  • You want to stop taking Xl 80 tablets.
  • You develop an allergy to Xl 80 ( rashes, hives, swelling on the hands or face).
  • Any other medical issues that arise after you start taking Xl 80 tablets.
  • If Xl 80 tablet does not seem to help you.

Mode of Action of Xl 80 Tablet

How Does It Work?

Xl 80 tablets contain codeine and chlorpheniramine. Codeine is an opioid( derived from the poppy plant) analgesic (painkiller). It primarily acts by attaching itself to the mu-opioid receptors in the ...
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Directions for Use of Xl 80 Tablet

  • Xl 80 tablet is taken orally with water with or without food.
  • It should be taken as prescribed by your doctor after evaluation of your condition.
  • Do not chew or crush the tablet in powder form.
  • Do not change the dose without consultation with your physician.
  • Do not share medication with anyone you know who has the same symptoms.

Interactions of Xl 80 Tablet

Interactions with other medicines

  • Anti-anxiety medications can increase side effects with Xl 80 tablets and cause severe respiratory depression.
  • Anticholinergics like atropine, benztropine and cyclopentolate can cause respiratory problems when taken with Xl tablets.
  • Medicines for vomiting, anaesthetics and sedative-hypnotics like Zolpidem taken along with Xl 80 tablets can depress the central nervous system.
  • Antipsychotics like phenothiazine can severely depress the nervous system causing breathing difficulties, fainting, coma.
  • Monoamine oxidase inhibitors (antidepressants like isocarboxazid, phenelzine, selegiline) should be taken only in a gap of 14 days after stopping this medication.
  • Nalbuphine (an opioid painkiller) and Xl 80 tablets can cause a high degree of sedation and worsen intestinal obstruction.

Interactions with food items

  • Xl 80 tablet does not show any adverse reactions when taken along with any food.

Storage and disposal of Xl 80 Tablet

Xl 80 tablet comes in a box containing a strip of 10 tablets. It is to be kept at room temperature, away from direct sunlight. It should be kept away from children and pets at home. Disposal of exp...
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Dosage of Xl 80 Tablet


Overdose of Xl 80 tablets can be accidental to make up for missed doses or to increase its efficacy. It can also be intentional, especially in patients with a known history of substance abuse. Such c...
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Missed a Dose

If you realise you have missed a dose of Xl 80 tablet, you can take it immediately. If the next scheduled dose is only a few hours away, then it is better to skip the missed dose and take the next sch...
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Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: Can Xl 80 tablets be addictive?

A: Yes, the Xl 80 tablet carries the potential of being addictive after prolonged use. Patients with a known history of substance abuse should be monitored regularly by family members. It should only be taken exactly as prescribed by the doctor. No changes in doses/duration should be made without consulting your physician.

Q: Can Xl 80 tablets make me sleepy?

A: Yes, it causes side effects like lightheadedness, dizziness and the codeine content of the medicine reduces the excitability of nerve cells, thus enhancing the sleep effect.

Q: Can I give Xl 80 tablets to my friend who has a common cold?

A: Xl 80 tablet should only be taken if prescribed. Your physician will advise you to take it after evaluating your medical condition. It is not advised to share the medicine with anyone you know without proper medical consultation.
Product Details
XL 80
Expires on or After
Last Updated on: 04 Mar 2022 | 04:53 PM (IST)

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