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Sizopin 100mg Tablet
Sizopin 100mg Tablet

Sizopin 100mg Tablet

10 Tablet(s) in Strip
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Sizopin 100 MG Description

Sizopin tablets contain Clozapine as its active ingredient. Clozapine belongs to a category of medications known as atypical antipsychotics. It is used to treat severe Schizophrenia, especially when

the first-line medication therapy fails to show the desired effects. It can also be used to treat Parkinson‘s disease, bipolar disorder or mood disorders. It acts by regulating certain brain chemicals to relieve symptoms which helps improve behaviour, mood and quality of life. It needs to be taken orally with water with or without food. Sizopin can cause side effects such as increased heart rate, dizziness, headache and blurry vision. It is generally used to treat adult psychiatric disorders and is not recommended for children below 18 years. Sizopin can cause or worsen a blood disorder which prolongs bleeding time, so care should be taken to do the required tests before starting on this medication. Older patients with dementia should not take Sizopin tablet.


Product Summary

Offer Price₹71.77
You Save₹12.67 (15% on MRP)
ContainsClozapine(100.0 Mg)
UsesSchizophrenia, bipolar disorder, mood disorders, Parkinson’s disease.
Side effectsDizziness, increased heart rate, fainting, muscle tremors, seizures, high blood glucose, glaucoma.
Check more medicines with composition as Clozapine(100.0 Mg)

Uses of Sizopin 100 MG

  • Schizophrenia to help alleviate symptoms.
  • Cases of Parkinson’s disease, when first-line medicines do not work or give the desired outcome.
  • Bipolar disorder.
  • Some cases of severe mood disorders.

Contraindications of Sizopin 100 MG

  • Allergy to the components of Sizopin.
  • Old patients with Dementia.
  • Increased glucose levels after use or pre-existing diabetes.
  • Bleeding disorders.
  • Seizure history.
  • History of brain tissue disorders.
  • History of / present cardiac ailments.
  • Low magnesium/potassium in the blood.
  • Very obese patients.
  • Low blood pressure.
  • Closed-angle glaucoma.

Side effects of Sizopin 100 MG

  • Increased glucose levels
  • Blurry vision
  • Tremors
  • Dizziness
  • Headache
  • Increased heart rate
  • Weight gain

Precautions and Warnings of Sizopin 100 MG



Can I take Sizopin during pregnancy?
Sizopin may not be advised in pregnancy. You may be prescribed a lower dose as Clozapine is considered safe for mother and foetus only in smaller doses based on limited human studies. Talk to your doctor if you are pregnant or planning a pregnancy.

Breast Feeding

Can I take Sizopin while breastfeeding?
No, Sizopin is not usually prescribed during breastfeeding as it passes through the breast milk from mother to child in high amounts and may cause adverse side effects like sleepiness, increased heart rate and high glucose levels.


Can I drive if I have taken Sizopin?
Sizopin may cause side effects like blurred vision, headaches and uncontrolled muscle movements; Therefore, handling any heavy machinery and driving are not recommended within hours of taking the medication.


Can I consume alcohol with Sizopin?
No, alcohol consumption is prohibited while on therapy with Sizopin as it may increase the severity of side effects like blurry vision, dizziness and uncontrolled tremors.

Other General Warnings

Talk to your doctor if
  • You have persistent side effects which do not go away with use and worsen over time.
  • You develop an allergy to Sizopin (rashes, hives and swelling on the face)
  • You feel that Sizopin does not seem to work for you.
  • You want to change your dose or stop taking Sizopin.
  • You have missed any doses of Sizopin.
  • You develop any other medical issue while on therapy with Sizopin.

Mode of Action of Sizopin 100 MG

How Does It Work?

Sizopin is primarily used in treating Schizophrenia when all the other types of treatment have not helped the patient. Schizophrenia is characterised by symptoms of hallucinations (where the patient r...
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Directions for Use of Sizopin 100 MG

  • Sizopin can be taken with or without food. The tablets are to be consumed whole with water. It is not advised to chew or to crush tablets in powder form. It Is recommended to take medicine every day a...
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Interactions of Sizopin 100 MG

Interactions with other medicines

  • Antidepressants like fluvoxamine, fluoxetine, and paroxetine can increase the levels of Sizopin tablets.
  • Antibiotics like ciprofloxacin, cimetidine, azithromycin, or erythromycin increase the level of Clozapine in the body.
  • Antibiotics like Rifampicin and medicines used for gastric ulcers and diseases like Omeprazole can increase levels of Clozapine in the body leading to the possibility of side effects like dizziness, h...
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  • Medications like Phenobarbitone can decrease levels of Clozapine in the body.
  • Benzodiazepines can cause slow or laboured breathing when taken with Sizopin.
  • Antihistamines like Promethazine can increase sleepiness when taken along with Sizopin.
  • Along with Sizopin, antispasmodics like atropine can relax the gastrointestinal tract causing pain, constipation and urine retention.
  • Blood pressure medications can enhance the blood pressure-lowering effect of Sizopin.
  • Antipsychotics like chlorpromazine, pericyazine, or risperidone can also cause delirium (confused thinking), constipation and urinary retention when taken along with Sizopin.

Interactions with food items

  • Sizopin has no reported cases of adverse food reactions.

Storage and disposal of Sizopin 100 MG

It should be kept at room temperature, away from damp areas. Sizopin should be kept away from children and pets at home. Disposal of Sizopin should be done along with other medical wastes. Do not drai...
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Dosage of Sizopin 100 MG


Very high doses of Sizopin can cause cardiac toxicity. Overdose of Sizopin can cause dizziness, fainting or seizures. It can be fatal in older patients with other medical complications. Some published...
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Missed a Dose

Sizopin is usually recommended to be taken at the same time every day. Any missed dose can be made up for within a few hours. If the next scheduled dose is a few hours away, skip the missed dose and t...
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Content Details


Dr. Anuj Tiwari

MBBS, DNB Medicine

Frequently Asked Questions (FAQs)


Q: How long will it take for Sizopin to work for me?

A: Like most psychiatric medications, it may take a few weeks before you feel the full effect of taking Sizopin. It may be 4-12 weeks before you start feeling better.

Q: What should I do if I don’t want to take Sizopin anymore?

A: Do not discontinue the medication on your own. Talk to your physician, who will then taper the dose before stopping it. Stopping Sizopin abruptly can cause severe withdrawal symptoms like fainting, dizziness and loss of coordination.

Q: Will Sizopin have any effect on my sleep?

A: Sizopin has proven to help sleep continuity when taken as prescribed by your physician. As per some published studies it seems to improve stage 2 sleep (deep sleep).
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Last Updated on: 01 Mar 2022 | 11:50 AM (IST)
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