Sizopin 100mg Strip Of 10 Tablets
10 Tablet(s) in StripWe do not sell this product
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SUN PHARMA
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Clozapine(100.0 Mg) |
| Uses | Schizophrenia, bipolar disorder, mood disorders, Parkinson’s disease. |
| Therapy | Anti-psychotics |
| Side effects | Dizziness, increased heart rate, fainting, muscle tremors, seizures, high blood glucose, glaucoma. |
Assurance
available
Regulated
Medical Description
Sizopin tablets contain Clozapine as its active ingredient. Clozapine belongs to a category of medications known as atypical antipsychotics. It is used to treat severe Schizophrenia, especially when the first-line medication therapy fails to show the desired effects. It can also be used to treat Parkinson‘s disease, bipolar disorder or mood disorders. It acts by regulating certain brain chemicals to relieve symptoms which helps improve behaviour, mood and quality of life.
It needs to be taken orally with water with or without food. Sizopin can cause side effects such as increased heart rate, dizziness, headache and blurry vision. It is generally used to treat adult psychiatric disorders and is not recommended for children below 18 years.
Sizopin can cause or worsen a blood disorder which prolongs bleeding time, so care should be taken to do the required tests before starting on this medication. Older patients with dementia should not take Sizopin tablet.
Uses
- Schizophrenia to help alleviate symptoms.
- Cases of Parkinson’s disease, when first-line medicines do not work or give the desired outcome.
- Bipolar disorder.
- Some cases of severe mood disorders.
Contraindications
- Allergy to the components of Sizopin.
- Old patients with Dementia.
- Increased glucose levels after use or pre-existing diabetes.
- Bleeding disorders.
- Seizure history.
- History of brain tissue disorders.
- History of / present cardiac ailments.
- Low magnesium/potassium in the blood.
- Very obese patients.
- Low blood pressure.
- Closed-angle glaucoma.
Side effects
- Increased glucose levels
- Blurry vision
- Tremors
- Dizziness
- Headache
- Increased heart rate
- Weight gain
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have persistent side effects which do not go away with use and worsen over time.
- You develop an allergy to Sizopin (rashes, hives and swelling on the face)
- You feel that Sizopin does not seem to work for you.
- You want to change your dose or stop taking Sizopin.
- You have missed any doses of Sizopin.
- You develop any other medical issue while on therapy with Sizopin.
Directions for Use
- Sizopin can be taken with or without food. The tablets are to be consumed whole with water. It is not advised to chew or to crush tablets in powder form. It Is recommended to take medicine every day at the same time. Do not stop taking Sizopin on your own even if you have started feeling better. There may be withdrawal symptoms like dizziness, disturbances in vision and fainting if you stop taking the medication abruptly. Your physician will taper down your dose if you need to stop the medicine.
Storage and disposal
It should be kept at room temperature, away from damp areas. Sizopin should be kept away from children and pets at home. Disposal of Sizopin should be done along with other medical wastes. Do not drain or dispose of the tablets in sinks or washrooms. Do not throw away unused medications along with other household wastes.
Dosage
Overdose
Very high doses of Sizopin can cause cardiac toxicity. Overdose of Sizopin can cause dizziness, fainting or seizures. It can be fatal in older patients with other medical complications. Some published cases have shown diabetic ketoacidosis or hyperglycaemia in overdoses of the medication Clozapine. Any overdose cases should immediately be reported to the emergency section of your nearest healthcare provider.
Missed a Dose
Sizopin is usually recommended to be taken at the same time every day. Any missed dose can be made up for within a few hours. If the next scheduled dose is a few hours away, skip the missed dose and take the next dose as scheduled. Do not take extra doses to make up for the missed dose. It is always better to talk to your physician about any missed doses.
Mode of Action
How Does It Work?
Sizopin is primarily used in treating Schizophrenia when all the other types of treatment have not helped the patient. Schizophrenia is characterised by symptoms of hallucinations (where the patient reports seeing and hearing instances that are not existent or real).
Sizopin contains Clozapine which belongs to the group of Antipsychotic medicines. Clozapine acts by blocking the effect of chemical messengers at the nerve cell junctions. Sizopin regulates the activity of dopamine and serotonin in the brain tissues in order to have a calming effect and improve the behaviour and mood in the patient's everyday life.
Interactions
Interactions with other medicines
- Antidepressants like fluvoxamine, fluoxetine, and paroxetine can increase the levels of Sizopin tablets.
- Antibiotics like ciprofloxacin, cimetidine, azithromycin, or erythromycin increase the level of Clozapine in the body.
- Antibiotics like Rifampicin and medicines used for gastric ulcers and diseases like Omeprazole can increase levels of Clozapine in the body leading to the possibility of side effects like dizziness, headaches and high blood sugar.
- Medications like Phenobarbitone can decrease levels of Clozapine in the body.
- Benzodiazepines can cause slow or laboured breathing when taken with Sizopin.
- Antihistamines like Promethazine can increase sleepiness when taken along with Sizopin.
- Along with Sizopin, antispasmodics like atropine can relax the gastrointestinal tract causing pain, constipation and urine retention.
- Blood pressure medications can enhance the blood pressure-lowering effect of Sizopin.
- Antipsychotics like chlorpromazine, pericyazine, or risperidone can also cause delirium (confused thinking), constipation and urinary retention when taken along with Sizopin.
Interactions with food items
- Sizopin has no reported cases of adverse food reactions.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:SIZOPIN
Manufacturer Name:SUN PHARMA
Address:<p>1. 90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001</p>
Country of Origin:India
Vendor Details
Fulfillment Information: Sizopin 100 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- .PubChem. Clozapine [Internet]. Nih.gov. [cited 2022 Feb 17]. Available from:
- 2.Hinze-Selch D, Mullington J, Orth A, Lauer CJ, Pollmächer T. Effects of clozapine on sleep: a longitudinal study. Biol Psychiatry [Internet]. 1997 [cited 2022 Feb 17];42(4):260–6. Available from
- 3. Nguyen HN, Lalonde P. Clozapine and pregnancy. Encephale [Internet]. 2003 [cited 2022 Feb 17];29(2):119–24. Available from:
- Clozapine: Elevated C-reactive protein and fever in an elderly patient: case report. React Wkly [Internet]. 2013 [cited 2022 Feb 17];1478(1):16–16. Available from:
- Chan NN. Clozapine and sudden death. Lancet [Internet]. 2000 [cited 2022 Feb 17];355(9206):841–2; author reply 843. Available from:
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