Roles D Capsule

• If you are allergic to this medicine or any of the ingredient of Roles-D capsule
• If you are taking any medicine which might affect the contraction of heart muscle (QT prolongation)
• If you are suffering from bleeding in the digestive system
• If you are suffering from liver or kidney disorder
• If you have serious heart problems like congestive heart failure, heart rhythm problems, electrolyte imbalance
• If you have any tumor of the pituitary gland (Prolactin pituitary tumours)
• If you are pregnant or breast feeding

• Headache
• Dizziness
• Nausea
• Vomiting
• Diarrhoea
• Stomach pain
• Cough

Other General Warnings

• You develop watery diarrhoea, fever after taking Roles-D capsule
• You experience black stools
• You have a stomach tumour
• You have a history of fractures or have osteoporosis or taking steroids
• You have liver and kidney disease or kidney failure
• You have heart problems and associated symptoms like palpitations, difficulty in breathing, unconsciousness
• You are on Roles-D capsule for more than three months. Your blood magnesium levels may drop. Your doctor may perform regular tests for the same
• You develop skin lesions especially in the sun exposed area after taking this medicine
• You are taking medicines to treat HIV
• You should not give this medicine to children of 12 years and below
• You have low levels of vitamin B12. This medicine is known to reduce the absorption of vitamin B12 after long term use. Supplements may be needed
• Taking this medicine for more than one year may increase chances of developing bone fractures

• Store Roles-D capsules below 25°C, protected from moisture and light
• Keep the medicine out of the reach of children

Overdose

• Symptoms of overdose include confusion, anxiety, fits, altered consciousness, sleepiness, etc.
• If you think you have taken too much of Roles-D capsule, contact your doctor immediately or visit the nearest hospital

Missed a Dose

• If you missed any dose of Roles-D capsule take it as soon as you remember
• If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule
• Do not take a double dose of medicine to compensate for the missed one

How Does It Work?

• A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Rabeprazole binds to this proton pump in stomach cells, thus blocking acid secretion
• Domperidone increases the motility of stomach and intestines so that acid does not reflux back into the food pipe

Interactions with other medicines

• Some medicines can affect the way Roles-D capsule works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Inform your doctor about all the medicines, supplements or herbals that you are currently taking or might take to avoid any possible interaction.
• Rilpivirine should never be taken along with this medicine
• Never take these medicines along with Roles-D Capsule: Disopyramide, Amiodarone; medicines for mental problems haloperidol, Citalopram; antibiotics like Erythromycin, Levofloxacin, Azithromycin; antifungals like Pentamidine, Ketoconazole and other medicines like Cisapride, Dolasetron, Mequitazine etc.
• This medicine interferes with the action of antiviral medicines like Rilpivirine, Atazanavir and Nelfinavir and antifungals like Posaconazole, Ketoconazole and Itraconazole
• Medicine used to treat heart failure like digoxin may lead to toxicity when taken with this medicine.
• Medicines used for mental disorders like Diazepam, Phenytoin
• If you are taking Warfarin, caution is needed as there are chances of increased bleeding.

Interactions with food items

• Roles-D capsule should preferably be taken on an empty stomach
• There are no known interactions with food or beverages
• However, nicotine and caffeine (coffee, tea, chocolate and cola) can increase stomach acid or delay ulcer healing and hinder the treatment process