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Primigyn 0.5% Gel

3g Vaginal Gel in Tube
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Primigyn 0.5 MG Description

Primigyn 0.5% Gel is a medication for inducing or starting labour in women who can give birth to a full-term baby. The gel softens and widens the cervix or lower end of the uterus, making it easier f

or the baby to pass through. The mode of action of Primigyn 0.5% gel is by widening the birth canal or cervix and forcing the uterus to contract so the baby can pass through. Primigyn 0.5% gel is not for self-application. It should only be applied under the guidance of a medical healthcare expert in a hospital environment. The amount of gel required and the frequency at which it should be reapplied can vary. The doctor will decide this based on the affected person's health condition. The user should lie down for 30 minutes after application of the gel. This gel should be used with caution on persons with kidney or liver illness, asthma, high or low blood pressure, and those who recently had a heart attack. Side effects of Primigyn 0.5% gel include backache and skin burning. It is important to share any discomfort with the treating doctor as it may indicate reduced or nullified impact of Primigyn 0.5% gel. The doctor must also be mindful of any other medications being taken currently, as some of these may reduce the effectiveness or alter the functioning of Primigyn 0.5% gel. While taking this prescription, the doctor needs to monitor the user's contractions.


Product Summary

Offer Price₹203.74
You Save₹33.17 (14% on MRP)
ContainsDinoprostone(0.5 Mg)
UsesInducing labour pain in pregnant women
Side effectsIncreased uterine contractions, Vomiting, Flushing of the skin, Back pain, Foetal distress, Diarrhoea
Check more medicines with composition as Dinoprostone(0.5 Mg)

Uses of Primigyn 0.5 MG

  • As per CDSCO, Primigyn 0.5% gel induces labour pain in pregnant women.

Contraindications of Primigyn 0.5 MG

  • Primigyn 0.5% gel is contraindicated:
  • If you are allergic to the gel or its oxytocic agents
  • If you are hypersensitive to prostaglandins
  • If you have a history of major uterine surgery or caesarean section (C-section)
  • If you have hypertonic or hyperactive uterine patterns
  • If you have a history of difficult labour or delivery
  • If you do not have an indication of vaginal or normal delivery

Side effects of Primigyn 0.5 MG

  • Side effects of Primigyn 0.5% gel include:
  • Increased uterine contractions
  • Vomiting
  • Flushing of the skin
  • Back pain
  • Foetal distress
  • Diarrhoea

Precautions and Warnings of Primigyn 0.5 MG



Can I take Primigyn 0.5% gel during pregnancy?
Using Primigyn 0.5% gel during pregnancy is generally viewed as safe. Animal research has shown little or no adverse effects on the growing foetus; however, human studies are scarce.

Breast Feeding

Can I take Primigyn 0.5% gel while breastfeeding?
It is unsafe to use Primigyn 0.5% gel while nursing. According to minimal human research, the medicine shall transfer into breast milk and harm the newborn.


Can I drive if I have taken Primigyn 0.5% gel?
Primigyn 0.5% gel can cause uterine contractions, leading to childbirth. Driving a car under such circumstances will be extremely dangerous.


Can I consume alcohol with Primigyn 0.5% gel?
Do not drink alcohol if you have been prescribed Primigyn 0.5% gel. If you have already consumed alcohol, tell your healthcare practitioner.

Other General Warnings

Talk to your doctor if
  • You will use Primigyn 0.5% gel only at a hospital or clinic.
  • You should lie down for nearly half an hour to keep the gel in place. Your doctor will help you with the application and precautions.
  • You shall have your second dosage as per your healthcare practitioner's advice. For example, you will be given a double dose only if your contractions aren't powerful enough.
  • You will be under observation by your medical practitioner to ensure that the contractions do not grow too powerful and that the baby is not disturbed.
  • You have heart, renal, lung, or liver illness or a history of asthma.
  • You have genital herpes.

Mode of Action of Primigyn 0.5 MG

How Does It Work?

Primigyn 0.5% gel is identical to E2 prostaglandin, a natural chemical made by the body as labour begins. It works by widening the birth canal or cervix and forcing the uterus to contract so the baby ...
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Directions for Use of Primigyn 0.5 MG

  • Your doctor will change your Primigyn 0.5% gel dose during your therapy based on your contraction pattern and the adverse effects you encounter.
  • Discuss how you're feeling during your Primigyn 0.5% gel therapy with your doctor.
  • Primigyn 0.5% gel should not be used outside the body.
  • Primigyn 0.5% gel should be used according to the doctor's instructions on quantity and length. Only a healthcare expert under careful medical supervision in a hospital setting shall use the gel for a...
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  • Do not self administer.
  • Also, after using Primigyn 0.5% gel, lie flat for 30 minutes.
  • If you've been given a suppository form, it shall be removed right before you go into labour.

Interactions of Primigyn 0.5 MG

Interactions with other medicines

  • Primigyn 0.5% Gel may interact with the following medication and cause side effects such as rashes, itching, and hives.
  • Oxytocic medicines like Oxytocin and Carbetocin
  • Ergot alkaloids such as Methylergonovine and Ergonovine

Storage and disposal of Primigyn 0.5 MG

Primigyn 0.5% gel should be stored in a refrigerator at temperatures of 2-8°C. Hospitals generally store the gel in the fridge and not freeze it.

Dosage of Primigyn 0.5 MG


If you feel you have an overdose, call your doctor right away. Seek medical treatment if the user has passed out, had a seizure, has problems breathing, or cannot be woken. Overdosing on Primigyn 0....
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Missed a Dose

Since there is no self-application for Primigyn 0.5% gel, there are no chances of a missed dose. Your medical examiner shall offer the second dose in critical situations.

Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: What precautions should I take before using Primigyn 0.5% gel?

A: Please clarify with your physician if you have had a previous preterm birth, c-section, or cervical surgery before commencing with Primigyn 0.5% gel application. Provide your practitioner with a thorough medical history to minimise difficulties.

Q: Can I take the second dose of Primigyn 0.5% gel if my contractions aren't powerful?

A: No. It would be best if you had the second dose of Primigyn 0.5% gel according to the doctor's instructions for dosage and frequency. It may produce foetal distress or birth difficulties if you take more than the prescribed quantity.

Q: Is it safe for me to use Primigyn 0.5% gel if I am a 35-year-old woman?

A: You will Primigyn 0.5% only if your healthcare practitioner has prescribed it. The risk of significant problems after the application of this gel is higher in women over 35. This risk is amplified in smokers.
Product Details
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Last Updated on: 14 Mar 2022 | 10:03 AM (IST)

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