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Ambistryn S 1 Gm Injection

1 Injection(s) in Vial
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Ambistryn S 1 G Description

Ambistryn S 1 Gm Inj is an antibiotic medicine containing streptomycin 1 g in powder form. It belongs to the aminoglycoside group of medicine, approved for the treatment of tuberculosis (TB) in combi

nation with other antitubercular medicines. It works by limiting the further growth of TB bacteria. It is not currently indicated for the treatment of any other infections because of its complications and interaction issues. Directions for use of Ambistryn S 1 Gm Inj should be strictly followed. This medicine shouldn’t be self-administered instead given by a nurse or doctor. It is usually prescribed for a few initial months in the entire treatment course of TB. It is directly injected into a muscle. The entire course of treatment with Ambistryn S 1 Gm Inj should be completed, even if the affected person feels better. Suddenly stopping anti-TB treatment may worsen the disease by its spread or developing resistance towards this medicine or relapse of the infection. Current strains of TB bacteria tend to be resistant to streptomycin; hence higher antibiotics have replaced Ambistryn S 1 Gm Inj to some extent. Side effects of Ambistryn S 1 Gm Inj include skin rashes, vomiting, fever, and vertigo. It is also known to harm the kidneys and ear if it reaches toxicity or during long-term use. Monitoring of kidney function tests, hearing tests, and urine tests are conducted during this injection treatment. Ambistryn S 1 Gm Inj is contraindicated in pregnancy.


Product Summary

Offer Price₹10.67
You Save₹1.46 (12% on MRP)
ContainsStreptomycin(1.0 G)
Side effectsNausea and vomiting; Diarrhoea; Decreased appetite, Pain at the injection site; Fever; Vertigo and dizziness; Skin rash; Itching; Swelling over eyes, face, and lips; Hoarse voice
Check more medicines with composition as Streptomycin(1.0 G)

Uses of Ambistryn S 1 G

  • Ambistryn S 1 Gm Inj is combined with other antitubercular medicines to treat tuberculosis (TB) affecting the lungs or any other organ in the body. It stops the replication of Mycobacterium tuberculi,...
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Contraindications of Ambistryn S 1 G

  • Do not take Ambistryn S 1 Gm Inj or use caution:
  • If you are allergic to Ambistryn S 1 Gm Inj or its variants like gentamicin, etc.
  • If you have been diagnosed with myasthenia gravis
  • If you have been diagnosed with cystic fibrosis
  • If you have been diagnosed with Parkinson’s disease
  • If you have chronic kidney disease
  • If you are pregnant

Side effects of Ambistryn S 1 G

  • Common side-effects of Ambistryn S 1 Gm Inj include:
  • Nausea and vomiting
  • Diarrhoea
  • Decreased appetite
  • Pain at the injection site
  • Fever
  • Vertigo and dizziness
  • Skin rash with itching
  • Swelling of eyes, face, and lips
  • Hoarse voice

Precautions and Warnings of Ambistryn S 1 G



Can I take Ambistryn S 1 Gm Inj during pregnancy?
Ambistryn S 1 Gm Inj is unsafe for pregnant women. It poses a risk to the developing foetus. It may cause hearing difficulties and other developmental drawbacks in the infant. The doctor will prescribe this injection only if the benefits outweigh the risks.

Breast Feeding

Can I take Ambistryn S 1 Gm Inj while breastfeeding?
Ambistryn S 1 Gm Inj is safe in women who are breastfeeding. As per human studies, this medicine does not pass into breast milk in amounts that can harm the baby.


Is it okay to drive after taking an Ambistryn S 1 Gm Inj?
Ambistryn S 1 Gm Inj may show side effects in some people, which affect their driving skills. So, it is better not to drive during the initial few doses until you know what side effects you can have.


Can I consume alcohol with the Ambistryn S 1 Gm Inj?
Consumption of alcohol with Ambistryn S 1 Gm Inj does not cause any direct harmful side effects.

Other General Warnings

Talk to your doctor if
  • You have an allergic reaction to Ambistryn S 1 Gm Inj. These may manifest as skin rash, swelling and redness in the mouth or face, and breathing difficulties. Discontinue in case of an allergy.
  • You are pregnant, planning to conceive, or breastfeeding.
  • Your doctor may regularly monitor your blood, hearing, and urine tests at fixed intervals when you are on this medicine.
  • Your doctor should know about all your medical conditions and the medicines you take for them. This will also prevent medicine reactions.
  • You experience any serious side-effects that have not settled and or are worsening.

Mode of Action of Ambistryn S 1 G

How Does It Work?

Ambistryn S 1 Gm Inj works as an antibiotic. It limits the growth of the bacteria by restricting the synthesis of the proteins that are essential for the bacteria to survive and replicate. It is given...
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Directions for Use of Ambistryn S 1 G

  • A physician should prescribe the dose of Ambistryn S 1 Gm Inj.
  • A trained medical professional should strictly administer it.
  • It should be used within four days when stored in a cold place.
  • Ambistryn S 1 Gm Inj comes in the form of a vial.
  • Add 2 ml or more sterile water to reconstitute the injection (check label instructions).
  • The reconstituted solution should be injected into a muscle.
  • Shake well before use.
  • It is essential to be hydrated when Ambistryn S 1 Gm Inj is administered.

Interactions of Ambistryn S 1 G

Interactions with other medicines

  • Ambistryn S 1 Gm Inj can interact with other medicines and cause adverse side effects. It is advised to inform the doctor of all medication being taken to be checked for possible interaction issues. T...
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  • Regular monitoring of kidney function tests needs to be done in case of concomitant use with abacavir and adefovir.
  • Blood calcium and magnesium levels should be monitored in concomitant use with alendronic acid.
  • Medicines like antibiotics of the penicillin group (ampicillin, augmentin, and amoxicillin) can worsen the allergic reaction and increase the chances of anaphylaxis (severe allergy).
  • Non-steroidal anti-inflammatory drugs (NSAIDs) like indomethacin increase Ambistryn S 1 Gm Inj levels in the blood by decreasing its clearance from the kidney.

Storage and disposal of Ambistryn S 1 G

Ambistryn S 1 Gm Inj should be stored in a cool and dry place. Ambistryn S 1 Gm Inj should be kept away from children and pets. Leftover or expired medicine should be disposed of with precautions that...
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Dosage of Ambistryn S 1 G


Ambistryn S 1 Gm Inj has to be taken in doses recommended by a doctor. Overdose can increase the risk of side effects like nausea and vomiting, diarrhoea, decreased appetite, pain at the injection sit...
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Missed a Dose

In case of a missed dose of Ambistryn S 1 Gm Inj, it is suggested to take the next dose as per the regular schedule. Never take two doses at the same time.

Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: What are the adverse effects caused by use of Ambistryn S 1 Gm Inj?

A: Ambistryn S 1 Gm Inj can cause serious kidney problems, more common in dehydrated and older adults. Presenting symptoms are general weakness, swelling over the face and extremities of the body, and decreased urination. It may also cause serious hearing issues with symptoms like vertigo, dizziness, loss of hearing, or ringing in the ears. Nerve problems like tingling numbness in hands, feet, legs, muscle twitches, etc., can occur. If you experience any of the above symptoms, follow up with your doctor immediately.

Q: What if my symptoms don't improve with Ambistryn S 1 Gm Inj?

A: Wait till you finish the entire course of treatment. If you still don’t feel better, inform the doctor. You might require a dose change or an alternate treatment plan. Consult your doctor for guidance.

Q: Will Ambistryn S 1 Gm Inj certainly affect my liver or kidney?

A: Ambistryn S 1 Gm Inj has adverse reactions that may affect the kidney. It doesn’t bother the liver as much. However, pre-existing liver and kidney conditions may need titration of regular dose. In liver damage individuals, the dose should be evaluated.
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Last Updated on: 30 Mar 2022 | 10:25 AM (IST)

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