Oxytocin
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Molecule Description
Oxytocin is a hormone-based injection used in hospitals to help start or strengthen labour in full-term pregnant women when needed. It works by causing the uterus to contract more effectively, helping with the progression of childbirth. After delivery, doctors may also use Oxytocin to prevent or control excessive bleeding by helping the uterus tighten and return to its normal size. Since it acts strongly on the uterus, Oxytocin is always given under careful medical supervision, with continuous monitoring of both the mother and the baby to ensure safety and proper response.
Uses
- Oxytocin is used in pregnant women to induce labour.
- It can also be used to control bleeding post-delivery.
Contraindications
When should one not use Oxytocin
- If you are allergic to oxytocin
- If you have problems with your heart or blood circulation
- If you are suffering from a condition called preeclamptic toxaemia (symptoms may include high blood pressure, protein in the urine and swelling)
- If there is an obstruction to normal delivery or normal delivery is not possible
- If you have strong uterine contractions
- If you have been given vaginal prostaglandins
Side effects
Common side effects of this drug are:
- Nausea
- Vomiting
- Headache
- Stomach pain
- Drowsiness
- Uneven heartbeats
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a history of caesarean section
- You have chest pain
- You have pre-existing heart disease, blood circulation problems, high blood pressure or kidney disease
- Your age is more than 35 years
- If normal delivery is difficult
- You had complications during your pregnancy
- Duration of your pregnancy is more than 40 weeks
Mode of Action
How Does It Work?
Oxytocin works by stimulating the uterine walls of the women, causing uterine contractions by changing the calcium concentrations in the uterine muscle cells. This induces labour and the child is delivered.
Interactions
Interactions with other medicines
Some medicines can affect the way oxytocin works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
Prostaglandins, medicines used in epidural anaesthesia, cough and cold medicines containing decongestants, medicines containing caffeine or other stimulant medicines and other hormones used for various medical conditions.
Interactions with food items
It is given only at the time of labour in a hospital setup. Hence, interaction with food is minimal. The doctor should be consulted for any food interactions. Fluid intake should be minimum as retention of fluid in the body may occur.
Frequently Asked Questions (FAQs)
Articles
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References:
- Oxytocin 10 IU/ml Concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 7 February 2022]
- Oxytocin 10 IU/ml Concentrate for Solution for Infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 7 February 2022]
- Oxytocin [Internet]. Dailymed.nlm.nih.gov. 2021 [cited 7 February 2022]
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