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Amikacin

Molecule Description

Amikacin belongs to Aminoglycoside antibiotics class that is used to prevent or treat bacterial infections.

Uses of Amikacin

Amikacin is an antibiotic used to treat conditions such as serious infection by certain bacteria, including joint infection, intra-abdominal infections, pneumonia, and urinary tract infections.

Contraindications of Amikacin

When should one not use Amikacin

  • A known allergy to any aminoglycoside
  • You suffer from a disease called myasthenia gravis (severe weakness)
  • If you have hearing difficulty, nerve problems or kidney problem

Side effects of Amikacin

Common side effects of this drug are:

  • Skin rash
  • Cough
  • Dizziness
  • Drowsiness
  • Fever
  • Headache
  • Loss of balance
  • Nausea, vomiting
  • Low blood pressure
  • Deafness
  • Severe kidney failure
  • Decrease in the number of red blood cells in the blood (anemia) or excessive amounts of the white blood cells known as Eosinophils in the blood (eosinophilia)

Precautions and Warnings of Amikacin

Pregnancy

Q:
Can I take Amikacin during pregnancy?
A:
It is not recommended by experts to use this medicine during pregnancy. This medicine can cause fetal harm when taken by a pregnant woman.

Breast Feeding

Q:
Can I take Amikacin while breastfeeding?
A:
Amikacin passes into breast milk in small amounts. Consult your doctor before breastfeeding.

Driving

Q:
Can I drive if I have consumed Amikacin?
A:
If you experience any side effects like dizziness during treatment, then avoid driving.

Alcohol

Q:
Can I consume alcohol with Amikacin?
A:
Interaction with alcohol is unknown.

Other General Warnings

Talk to your doctor if
  • Have kidney problems
  • You have hearing difficulties or tinnitus (ringing or buzzing in the ears)
  • Amikacin may cause live bacterial vaccines (such as typhoid vaccine) not to work well. Do not have any immunizations or vaccinations while using this medication unless your doctor advises you.
  • Amikacin may cause kidney damage, hearing loss for the elderly population, or infants who are on a higher dose of Amikacin; hence, one has to be cautious while giving this medicine to elderly or infants.
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Mode of Action of Amikacin

How Does It Work?

Amikacin works by stopping the growth of bacteria.

Interactions of Amikacin

Interactions with other medicines

It is essential to let your doctor know about all the medications you are taking. Medicines that may interact with Mikacin include Amphotericin B, Cephalosporin, Cisplatin, Cyclosporine, Diuretics like Furosemide, and Ethacrynic Acid, anti-inflammatory drugs (NSAIDs) such as Ibuprofen, other Aminoglycosides and can increase the risk of kidney damage or hearing loss.
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Dosage of Amikacin

Overdose

Overdose of Amikacin cause severe kidney damage, after which the patient may need to be on lifelong peritoneal dialysis or hemodialysis.

Missed a Dose

If you have missed an Amikacin regular dose, then call your doctor and fix up an appointment as soon as you can. It is not advisable to miss a dose of antibiotics. It may lead to antibiotic resistance.
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Frequently Asked Questions (FAQs)

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Q: When and how to consume Amikacin?

A: Use this medicine with or without food. Take extra fluids while on treatment with this medicine. Do not take it in large amounts as it may cause undesirable effects.

Q: What should I discuss with my physician before taking Amikacin?

A: Give a detailed account of your medical and surgical history. Also, mention your doctor all the prescription and non-prescription medicines, herbal preparations, and nutritional supplements that you may be taking before starting this medication.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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