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Panazep Ls Tablets

10 Tablet(s) in Strip
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Panazep Ls Tablets Description

Panazep LS is prescribed by doctors to treat depression and anxiety disorders. Depression is a condition causing emotional and physical problems that may lead to feelings of sadness and loss of inter

est in the once enjoyed activities. It also causes difficulty in sleeping, anger, and loss of energy. The two active ingredients in Panazep LS – Clonazepam and Paroxetine bring about a calming effect in the brain and elevate the mood, improve sleep, and prevent feelings of sadness and loss. Panazep plus brings about specific changes in the brain’s chemical messengers, reducing abnormal activity in the nerve cells. It also increases the levels of hormones in your brain responsible for elevation mood and happy feelings. Panazep Ls is an effective medicine that comes as an extended-release tablet. This is a prescription-only medication.


Product Summary

Offer Price₹140.29
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ContainsParoxetine(12.5 Mg) + Clonazepam(0.25 Mg)
UsesDepression, generalised anxiety disorder
Side effectsDrowsiness, headache, nausea, vomiting, confusion, low blood pressure, breathing problem
Check more medicines with composition as Paroxetine(12.5 Mg) + Clonazepam(0.25 Mg)

Uses of Panazep Ls Tablets

  • Depression
  • Generalised anxiety disorder
  • Obsessive-compulsive disorder
  • Post-traumatic stress disorder
  • Social anxiety disorder
  • Epilepsy
  • Phobias

Contraindications of Panazep Ls Tablets

  • Allergy to clonazepam and paroxetine
  • Liver disease
  • Kidney disease
  • Heart problem
  • Respiratory disease
  • Alcohol or drug addiction
  • Children
  • Adolescents under 18 years of age

Side effects of Panazep Ls Tablets

  • Nausea
  • Headache
  • Sleepiness
  • Dryness of mouth
  • Constipation
  • Loss of appetite
  • Weight gain
  • Cognitive slowing
  • Confusion
  • Tiredness
  • Rare side effects
  • A sudden lowering of blood pressure
  • Convulsions
  • Unconsciousness
  • Breathing problem
  • Sexual dysfunction
  • Suicidal thoughts
  • Withdrawal symptoms
  • Anxiety
  • Nervousness
  • Difficulty falling asleep

Precautions and Warnings of Panazep Ls Tablets



Can I take Panazep LS during pregnancy?
No. The active ingredients in Panazep LS can cause harmful effects on the unborn child if it is taken during pregnancy. If you become pregnant while on treatment with Panazep LS, you should talk to your doctor about the risks to the child. You should discuss with your doctor if you are planning for pregnancy during the treatment.

Breast Feeding

Can I take Panazep LS while breastfeeding?
No. You should not take Panazep LS while breastfeeding the child as it passes through the breast milk and can cause adverse effects in the newborn.


Can I drive if I have a Panazep LS?
Panazep LS causes drowsiness, sleepiness and slows down the reflexes. Therefore, your ability to drive safely may be affected. You should avoid driving till you are sure that your side effects have been resolved. Discuss with your doctor before you start this medicine.


Can I consume alcohol with the Panazep LS?
No. Having alcohol while on treatment with Panazep LS increases the risk and intensity of the side effects such as vomiting, drowsiness, dizziness, and breathing problems. This can also prove to be fatal sometimes.

Other General Warnings

Talk to your doctor if
  • You have a history of allergy to any of the active ingredients in Panazep LS.
  • You have any other condition like liver disease, kidney disease, or heart problems.
  • You are on certain medications for other illnesses.
  • You have stopped the medicine abruptly. This may lead to withdrawal symptoms such as vomiting, convulsions, nervousness, low blood pressure, fainting, or return of symptoms with your doctor e medicine...
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  • Your side effects persist.
  • You have missed a regular check-up or counselling therapy session as was advised by the doctor.

Mode of Action of Panazep Ls Tablets

How Does It Work?

Panazep LS is used to treat depression and anxiety disorders. It helps elevate the mood, removing sadness, anger, and nervousness. It has two active ingredients in it - clonazepam and paroxetine. Par...
Read more

Directions for Use of Panazep Ls Tablets

  • You should use the Panazep LS tablet only under the guidance of your doctor. Your doctor shall assess your condition and recommend the dosage and the timing best suited to you.
  • It can be given with or without food as its absorption is not influenced by food.
  • The tablet is to be taken as a whole and not broken, chewed, or crushed.
  • Read the expiry date on the strip before starting the medicine course.
  • You should not stop the medicine abruptly without discussing it with your doctor.
  • If you stop the medicine suddenly, you may experience withdrawal symptoms such as convulsions, shaking, nervousness, and sleeplessness. Your doctor shall reduce the dose gradually.
  • The doctor shall adjust the dose of the medicine differently for elderly persons.
  • Usually, the side effects of the medicine subside after a while. Talk to the doctor if the side effects stay for long, even mild.

Interactions of Panazep Ls Tablets

Interactions with other medicines

  • Tricyclic antidepressants such as Desipramine, risperidone, atomoxetine.
  • Another antidepressant of the group called monoamine oxidase inhibitors such as isocarboxazid, phenelzine.
  • Phenothiazines such as fluphenazine, promazine, thioridazine
  • Certain drugs used for heart conditions such as flecainide, propafenone, rythmol
  • Blood-thinning medicines such as warfarin, aspirin
  • Non- steroidal anti-inflammatory medicines such as ibuprofen,
  • Opioid analgesics such as tramadol
  • Drugs used for convulsions such as phenytoin, phenobarbital, sodium valproate
  • Medicines for high blood pressure such as metoprolol
  • Narcotic drugs

Interactions with food items

  • You can continue with the usual diet. Food doesn’t interfere with the absorption of this medicine.
  • You can have the tablet with or without food.
  • Avoid caffeine, smoking, and alcohol.

Storage and disposal of Panazep Ls Tablets

Store the medicine at room temperature in a cool, dry place away from heat and humidity. Keep out of reach of children. If there are some leftover tablets after completing the recommended course, disp...
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Dosage of Panazep Ls Tablets


Overdose of Panazep LS may happen due to accidental intake, taking double dose due to a missed dose, or repeating the dose to have more effect or consuming more tablets intentionally. Symptoms of ove...
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Missed a Dose

Panazep LS should be taken according to thedoctor’s dose and the time advised. It is preferable to keep a fixed time for the medicine every day. If you have forgotten to take a dose and recall within ...
Read more

Content Details


Dr. Tulika Singh



Dr. Vineeti Dalal

MBBS, DNB Paediatrics, MRCPCH (UK)

Frequently Asked Questions (FAQs)


Q: What is the right time to take the Panazep LS tablet?

A: Your doctor shall advise you on the dose and timing of the medicine. Try taking it at a fixed time every day. Usually, it is advised at a time when you can take rest or sleep.

Q: What should I do if I develop a headache after starting the treatment with Panazep LS?

A: You should discuss with your doctor about any side effects you feel after starting the treatment. Usually, side effects subside as the body gets used to the medicine. You should take the medicine at a fixed time every day. Certain things chelp relieveeving headaches, such as drinking plenty of water, avoiding caffeine, not smoking, and exercising.

Q: Can I stop Panazep LS when I start feeling good?

A: No. You should complete the course of medicine as advised by the doctor. Your doctor shall call you for a checkup after the course is completed. He shall decide after talking to you whether you need to continue it further or not. This medicine should not be stopped suddenly. Doing that may result in serious withdrawal symptoms or recurrence of the symptoms you took the medicine.

Q: Do I need to make any changes in my habits and lifestyle to get cured of my condition?

A: Panazep LS may cause sleepiness. Avoid doing activities that require focus and quick reflexes such as driving, riding bikes, or machinery work. You should eat a balanced diet including green vegetables and grains, drink plenty of fluids, avoid caffeine, alcohol, and smoking. Adding exercise to your daily routine can also be helpful.
Product Details
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Last Updated on: 24 Jan 2022 | 03:39 PM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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