Zoetis Simparica Trio (Sarolaner) Tick And Flea Control Tablet For Dogs | 10-20Kg | 1 Tablet

Zoetis Simparica Trio is a flavoured chewable tablet for oral use in dogs aged 8 weeks or older and weighing 10 to 20 kg. It contains sarolaner, moxidectin and pyrantel pamoate for a monthly parasite routine.

• Give by mouth once each month under a veterinary doctor's direction.
• Make sure the dog consumes the complete dose and does not lose or refuse any part of it.
• If a dose is missed, give it immediately and resume monthly dosing.
• For seasonal mosquito exposure, use year-round or start within 1 month of the first exposure and continue until at least 1 month after the last exposure.
• For flea or tick season, treatment may begin at any time of year. Use monthly year-round or start at least 1 month before fleas or ticks become active.
• For the listed roundworms and hookworms, give a single dose. Monthly use is the stated schedule for later exposure.
• When changing from another monthly heartworm preventive, give this tablet within 1 month of the previous product's last dose.
• To help minimise flea re-infestation, treat all dogs and cats in the household with a flea-control product.

Reported reactions do not always show that the tablet caused them.

• Vomiting and diarrhoea, including diarrhoea with blood.
• Seizures, muscle tremors and ataxia, meaning loss of coordination.
• Lethargy, reduced appetite, itching and non-specific behaviour changes.

• For dogs only. Do not use in humans. Keep all medicines out of reach of children.
• Store securely away from dogs, cats and other animals to prevent accidental ingestion or overdose.
• Use with caution in dogs with a history of seizures or neurological disorders. Sarolaner belongs to an isoxazoline class associated with tremors, loss of coordination and seizures.
• Test for existing heartworm infection before use. A dog with an existing infection should receive an adulticide from a veterinary doctor. This tablet does not work against adult heartworms.
• Safe use has not been evaluated in breeding, pregnant or lactating dogs.

• Sarolaner: An isoxazoline that acts on nerve receptors in insects and ticks, disrupting normal nerve activity.
• Moxidectin: A macrocyclic lactone that interferes with nerve communication in parasites.
• Pyrantel pamoate: A tetrahydropyrimidine that affects nerve and muscle activity in susceptible worms, leading to paralysis or removal from the gut.
• Each tablet is formulated to provide minimum doses of 1.2 mg/kg sarolaner, 24 μg/kg moxidectin and 5 mg/kg pyrantel as pyrantel pamoate.

• A monthly routine may support management of adult fleas and listed ticks, including lone star, Gulf Coast, American dog, black-legged, brown dog and Asian longhorned ticks.
• For heartworm infection caused by Dirofilaria immitis, it may support protection when used on the recommended monthly schedule.
• For roundworms, use may support management of immature adult and adult Toxocara canis, and adult Toxascaris leonina.
• The tablet may support management of L4, immature adult and adult Ancylostoma caninum, and adult Uncinaria stenocephala hookworms.
• By killing vector fleas and ticks, it may support protection from Dipylidium caninum tapeworm and Borrelia burgdorferi infection.

• Flea reduction may begin within 4 hours after the first dose.
• For weekly flea re-exposure, laboratory studies reported at least 97.8% fewer live fleas within 12 hours for 28 days, and at least 99.7% effectiveness for 35 days in another study.
• By killing fleas before they lay eggs, it may help limit flea build-up for 35 days.
• Monthly administration may help manage the listed tick species for 1 month.
• When fleas are removed, it may help reduce flea-related itching, redness, bumps, scaling and hair loss.