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Zolpirest 10mg Tablets

10 Tablet(s) in Strip
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Zolpirest 10 MG Description

Zolpirest is a prescription medication. It is used in the short term management of insomnia or sleeplessness. The active component of Zolpirest is Zolpidem (10mg). Insomnia is a condition characteri

sed by persistent problems pertaining to falling and staying asleep. Zolpidem is particularly useful in the short term management of insomnia where there is difficulty in falling asleep. It prevents frequent awakenings at night and maintains adequate sleep duration. Zolpidem is a non-benzodiazepine that can cause sedation. It is essential to note that Zolpidem has habit-forming potential. It also has the potential to be misused. Hence, careful monitoring while on this medication is required and necessary. The medication should be taken as recommended by the doctor. It should not be abruptly started or stopped, as it may cause withdrawal effects. Taking the tablet at the same time every day is advisable for maximum efficacy.


Product Summary

Offer Price₹71.72
You Save₹9.78 (12% on MRP)
ContainsZolpidem(10.0 Mg)
UsesShort term treatment of insomnia
Side effectsDrowsiness, Dizziness, Diarrhoea, Nightmares, Agitation, Depression, Headache, Memory impairment, Fatigue, Cold, Cough
Check more medicines with composition as Zolpidem(10.0 Mg)

Uses of Zolpirest 10 MG

  • Short term management of insomnia

Contraindications of Zolpirest 10 MG

  • It is contraindicated in patients with known zolpidem hypersensitivity or known allergies to any components in this medication.
  • This medication should not be used in patients with any lung condition that results in difficulty in breathing or obstructive sleep apnea (a condition associated with snoring or trouble breathing whil...
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  • It is contraindicated for use in children.
  • This medication should not be used in patients with a known history of psychotic symptoms.
  • It is contraindicated in patients with liver failure.
  • It should not be used in patients with Myasthenia Gravis, a condition affecting muscles and respiration.
  • It is contraindicated in patients with rare hereditary problems of galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption.

Side effects of Zolpirest 10 MG

  • Drowsiness
  • Dizziness
  • Diarrhoea
  • Hallucination
  • Nightmares
  • Agitation
  • Depression
  • Headache
  • Memory impairment
  • Fatigue
  • Cold
  • Cough

Precautions and Warnings of Zolpirest 10 MG



Can I take Zolpirest during pregnancy?
This medication is considered unsafe in pregnancy. It is a Category C medication. This means that studies have shown that it can affect the growing foetus. Inform your doctor about your pregnancy, or intention to conceive at the time of prescription.

Breast Feeding

Can I take Zolpirest while breastfeeding?
This drug is considered unsafe during breastfeeding. Discuss with your doctor for more information.


Can I drive if I have taken Zolpirest?
Driving and operation of other heavy machinery while on this drug is not recommended as it causes light-headedness, sedation and sleepiness. There are also reports of sleep-driving and sleepwalking associated with Zolpidem.


Can I consume alcohol with the Zolpirest?
mixing alcohol with Zolpirest can cause life-threatening side effects on the user, as it can lead to respiratory depression, coma, and even death. It is strictly contraindicated.

Other General Warnings

Talk to your doctor if
  • If symptoms do not improve within 7-10 days of usage, inform your doctor immediately.
  • You should talk to your doctor if you have a history of addiction or substance misuse.
  • You should inform your doctor in case you are taking any other medications. The ingredients of this tablet may react with several other tablets that use the same pathway of metabolism in the body.
  • Inform your doctor if you experience any mood changes.

Mode of Action of Zolpirest 10 MG

How Does It Work?

Zolpidem is a non-benzodiazepine sedative and hypnotic agent. It produces sedation by affecting certain chemical messengers or neurotransmitters. The most significant neurotransmitter affected by Zolp...
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Directions for Use of Zolpirest 10 MG

  • This medication should be taken as prescribed by the treating physician.
  • It is recommended to take this medication on a regular schedule, i.e., at the same time every day, for optimal pharmacological effects of this medication.
  • Swallow this medication as a whole. Do not crush, chew or break this tablet.
  • If symptoms do not improve within 7-10 days of usage, inform your doctor immediately.
  • Take this medication before food. The absorption of Zolpidem is decreased by taking it with or immediately after food.
  • Abrupt stoppage of Zolpirest can cause withdrawal side effects. Consult your doctor before stopping this medication.
  • Driving/ use of heavy machinery is not advised while using this medication.
  • Do not mix alcohol with this medication, as it can be life-threatening.
  • This medication has habit-forming tendencies. Hence it is recommended to follow the directions of your treating physician precisely and have regular follow-ups.

Interactions of Zolpirest 10 MG

Interactions with other medicines

  • Combined use with central nervous system depressants like alcohol causes increased psycho-motor side effects.
  • The use of zolpidem with Imipramine, a tricyclic antidepressant, decreases one's alertness.
  • Impaired alertness is observed in patients who use zolpidem and chlorpromazine.
  • The concomitant use of Rifampin and Zolpidem decreases the efficacy of the latter.
  • Concomitant use of Ketoconazole and Zolpidem can decrease the efficacy of zolpidem.
  • The concomitant use of this medication with opioids (like morphine, tramadol etc.) is contraindicated, as it may cause respiratory depression, coma and death.
  • Inform your doctor regarding your current medications at the time of prescription of Zolpirest.

Storage and disposal of Zolpirest 10 MG

Store in a cool and dry place away from direct light and moisture. Do not use the medicine after the date of expiration. Keep the tablets away from children and pets. Do not flush the medication down ...
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Dosage of Zolpirest 10 MG


Symptoms may include excessive sleepiness, double vision, slurred speech and impaired movements. This may proceed to respiratory failure, fall in BP and heart rate, coma, cardiac arrest and even death...
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Missed a Dose

If you miss a dose of this tablet, it is advised to take it as soon as possible. If the duration missed is too long, and it is almost time for the next dose, it is recommended to skip the missed dose ...
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Content Details


Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)


Q: I have been using this tablet for a week now, but my symptoms have not improved. What should I do?

A: This medication is indicated for short term treatment of insomnia. If your symptoms do not settle within 7-10 days, inform your doctor immediately.

Q: I want to stop using this tablet. What should I do?

A: Abrupt stoppage of this medication can cause withdrawal symptoms which can be serious and debilitating. Consult your doctor for solutions and a safe manner to stop this medication if required.

Q: Since I started using this tablet, I have had a very restless sleep. I don’t feel fresh when I wake up. What should I do?

A: Zolpirest can result in nightmares or excessive drowsiness in some patients. Consult with your doctor regarding any side effects you might be facing to know if any change in medication or dose is required.
Product Details
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Last Updated on: 04 Jun 2022 | 07:02 PM (IST)

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