Zolpirest 10Mg Tablets
10 Tablet(s) in StripWe do not sell this product
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EAST WEST PHARMACEUTICALS PVT LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Zolpidem(10.0 Mg) |
| Uses | Short term treatment of insomnia |
| Therapy | Hypnotic |
| Side effects | Drowsiness, Dizziness, Diarrhoea, Nightmares, Agitation, Depression, Headache, Memory impairment, Fatigue, Cold, Cough |
Assurance
available
Regulated
Medical Description
Zolpirest is a prescription medication. It is used in the short term management of insomnia or sleeplessness. The active component of Zolpirest is Zolpidem (10mg).
Insomnia is a condition characterised by persistent problems pertaining to falling and staying asleep. Zolpidem is particularly useful in the short term management of insomnia where there is difficulty in falling asleep. It prevents frequent awakenings at night and maintains adequate sleep duration.
Zolpidem is a non-benzodiazepine that can cause sedation. It is essential to note that Zolpidem has habit-forming potential. It also has the potential to be misused. Hence, careful monitoring while on this medication is required and necessary.
The medication should be taken as recommended by the doctor. It should not be abruptly started or stopped, as it may cause withdrawal effects. Taking the tablet at the same time every day is advisable for maximum efficacy.
Uses
- Short term management of insomnia
Contraindications
- It is contraindicated in patients with known zolpidem hypersensitivity or known allergies to any components in this medication.
- This medication should not be used in patients with any lung condition that results in difficulty in breathing or obstructive sleep apnea (a condition associated with snoring or trouble breathing while sleeping).
- It is contraindicated for use in children.
- This medication should not be used in patients with a known history of psychotic symptoms.
- It is contraindicated in patients with liver failure.
- It should not be used in patients with Myasthenia Gravis, a condition affecting muscles and respiration.
- It is contraindicated in patients with rare hereditary problems of galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption.
Side effects
- Drowsiness
- Dizziness
- Diarrhoea
- Hallucination
- Nightmares
- Agitation
- Depression
- Headache
- Memory impairment
- Fatigue
- Cold
- Cough
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- If symptoms do not improve within 7-10 days of usage, inform your doctor immediately.
- You should talk to your doctor if you have a history of addiction or substance misuse.
- You should inform your doctor in case you are taking any other medications. The ingredients of this tablet may react with several other tablets that use the same pathway of metabolism in the body.
- Inform your doctor if you experience any mood changes.
Directions for Use
- This medication should be taken as prescribed by the treating physician.
- It is recommended to take this medication on a regular schedule, i.e., at the same time every day, for optimal pharmacological effects of this medication.
- Swallow this medication as a whole. Do not crush, chew or break this tablet.
- If symptoms do not improve within 7-10 days of usage, inform your doctor immediately.
- Take this medication before food. The absorption of Zolpidem is decreased by taking it with or immediately after food.
- Abrupt stoppage of Zolpirest can cause withdrawal side effects. Consult your doctor before stopping this medication.
- Driving/ use of heavy machinery is not advised while using this medication.
- Do not mix alcohol with this medication, as it can be life-threatening.
- This medication has habit-forming tendencies. Hence it is recommended to follow the directions of your treating physician precisely and have regular follow-ups.
Storage and disposal
Store in a cool and dry place away from direct light and moisture. Do not use the medicine after the date of expiration. Keep the tablets away from children and pets. Do not flush the medication down the toilet. Dispose of it with biomedical waste only.
Dosage
Overdose
Symptoms may include excessive sleepiness, double vision, slurred speech and impaired movements. This may proceed to respiratory failure, fall in BP and heart rate, coma, cardiac arrest and even death. In case of a suspected overdose, rush the patient to a tertiary care centre with ICU facilities for further evaluation and treatment.
Missed a Dose
If you miss a dose of this tablet, it is advised to take it as soon as possible. If the duration missed is too long, and it is almost time for the next dose, it is recommended to skip the missed dose and go back to the regular schedule. Do not double the dose of the tablet.
Mode of Action
How Does It Work?
Zolpidem is a non-benzodiazepine sedative and hypnotic agent. It produces sedation by affecting certain chemical messengers or neurotransmitters. The most significant neurotransmitter affected by Zolpidem is GABA (gamma-aminobutyric acid). It affects this neurotransmitter in specific parts of the brain that aid in the maintenance of deep sleep.
It is important to note that Zolpidem has addictive potential and can be a substance of misuse/ abuse. Careful monitoring is essential while on this medication.
Interactions
Interactions with other medicines
- Combined use with central nervous system depressants like alcohol causes increased psycho-motor side effects.
- The use of zolpidem with Imipramine, a tricyclic antidepressant, decreases one's alertness.
- Impaired alertness is observed in patients who use zolpidem and chlorpromazine.
- The concomitant use of Rifampin and Zolpidem decreases the efficacy of the latter.
- Concomitant use of Ketoconazole and Zolpidem can decrease the efficacy of zolpidem.
- The concomitant use of this medication with opioids (like morphine, tramadol etc.) is contraindicated, as it may cause respiratory depression, coma and death.
- Inform your doctor regarding your current medications at the time of prescription of Zolpirest.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:ZOLPIREST
Vendor Details
Fulfillment Information: Zolpirest 10 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Bouchette D, Akhondi H, Quick J. Zolpidem. [Updated 2022 Jan 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from
- Accessdata.fda.gov. 2022 [cited 11 March 2022]. Available from:
- Zolpidem Tartrate Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 11 March 2022]. Available from:
- Drugs@CDSCO [cited 11 March 2022]. Available from:
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