Spenzo Depot 40mg Injection 2ml
Spenzo Depot 40 MG Description
Spenzo is a prescription medication. It is available in the form of a depot injection. The active component of Spenzo is Flupentixol. Spenzo is an antipsychotic used to manage schizophrenia and other
forms of psychosis and depression associated with psychotic symptoms. Schizophrenia is a disorder where patients have an altered perception of reality, affecting how they feel, think, and behave. They can present with hallucinations, delusions, altered perceptions, mood changes, and disorderly thinking. There are certain chemical messengers (neurotransmitters), and pathways in the brain that are thought to produce the symptoms of schizophrenia, chief among which is the hyperactivity of one neurotransmitter called Dopamine. Depression is characterized by complaints like feeling low, decreased motivation, feelings of hopelessness and dread, and loss of interest in daily activities. Psychogenic depression can manifest with psychotic symptoms, like hallucinations and delusions, with severe loss of interest in activities and even suicidal ideation. Depot injections are designed to release small amounts of the medication over an extended period. This reduces the number of times the medicine has to be administered to the patient.
|Contains||Flupentixol / Flupenthixol(40.0 Mg)|
|Uses||Management of schizophrenia, psychogenic depression, and other forms of psychoses.|
|Side effects||Drowsiness, dry mouth, constipation, vomiting, abdominal pain, nausea,|
Uses of Spenzo Depot 40 MG
- Psychogenic Depression
Contraindications of Spenzo Depot 40 MG
- If you’re hypersensitive to Flupentixol or any component in this injection.
- If you’ve a decreased level of consciousness due to any cause or coma.
- If you have severe liver disease or kidney failure.
- If you have any heart disease.
- If you have severe respiratory failure, obstructive sleep apnea, or any conditions resulting in respiratory depression.
- If you have known epilepsy or any condition that predisposes seizures like alcohol withdrawal.
- If you have Parkinson’s disease.
- If you have prolactin-dependent tumours such as pituitary prolactinomas and breast cancer.
- If you have dementia with Lewy body.
- If you have narrow-angle glaucoma, urinary retention, or prostate enlargement.
- If you have thyroid disorders (hypothyroidism or hyperthyroidism).
- If you’ve Myasthenia gravis, a condition that affects muscle strength and respiration.
- If you have Phaeochromocytoma, a tumour of the adrenal glands.
Side effects of Spenzo Depot 40 MG
Precautions and Warnings of Spenzo Depot 40 MG
Other General Warnings
- You have a history of seizures or are taking any medications known to decrease seizure potential.
- You witness any sudden mood changes or worsening symptoms of schizophrenia
Mode of Action of Spenzo Depot 40 MG
How Does It Work?
Directions for Use of Spenzo Depot 40 MG
- Spenzo should be used as directed by your treating physician only.
- It should be administered only by a trained healthcare professional.
- Do not self-administer Spenzo.
- Spenzo should not be administered outside of a healthcare facility setting.
- Do not use it if the solution is not clear or has any suspended matter.
- It is recommended to finish the entire course of Spenzo as prescribed by your treating doctor. Abrupt stoppage of the medicine can cause recurrence/ worsening of symptoms. Consult your doctor before stopping Spenzo....
- Inform your doctor regarding other medications you may be taking to review and prevent any medicine interaction-associated effects.
Interactions of Spenzo Depot 40 MG
Interactions with other medicines
- The concomitant use of Flupentixol with CNS depressants like alcohol and barbiturates can potentiate their effects resulting in marked CNS depression.
- Flupentixol enhances the effects of general anaesthetics resulting in prolonged anaesthesia.
- It can increase the effect of anticoagulant medications resulting in bleeding.
- It increases the anticholinergic effects of medicines like atropine etc., resulting in marked urinary retention, constipation, orthostatic hypotension, pupillary constriction, sedation, hallucinations, and memory impairment....
- It should not be used with Metoclopramide, Piperazine, or anti-Parkinson medicines. This may increase the risk of Tardive Dyskinesia, a severe side effect characterised by uncontrollable, jerky movements of lips, face, trunk, and extremities....
- Spenzo can enhance the blood pressure lowering effects of medications like hydralazine, methyldopa, and alpha-blockers, resulting in marked hypotension.
- It enhances the cardiac depressant effects of quinidine and should not be used concomitantly.
- The combined use of lithium and sibutramine can result in increased neurotoxicity.
- It must not be used in combination with other medications that cause heart rhythm abnormalities.
- Spenzo inhibits the metabolism of tricyclic anti-depressants.
Interactions with food items
- Spenzo does not have any specific interaction with any food.
Storage and disposal of Spenzo Depot 40 MG
Dosage of Spenzo Depot 40 MG
Missed a Dose
Dr. Bhavika Shah
MBBS, MD (Dermatology), DNB (Dermatology)