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Solonex Dt 100mg Tablet

10 Tablet(s) in Strip
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Solonex Dt 100 MG Description

Solonex DT is an antibiotic used to treat tuberculosis. It is chemically composed of isoniazid or an isonicotinic acid hydrazide, an anti-tubercular medicine (treats tuberculosis infection). Fast mul

tiplying tuberculosis bacteria are rapidly killed, but the medicine only inhibits quiescent ones. It kills both extracellular and intracellular tuberculosis bacteria. Solonex DT is an essential component of all Tuberculosis treatment regimens. The medicine has to be taken orally on an empty stomach. The dose and the duration of the medicine have to be prescribed by your doctor. Do not skip any dose and complete the entire course of treatment as advised. Skipping doses or not completing the course might render the medicine ineffective in treating future infections. Common side effects are peripheral neuropathy (tingling and numbness of palms and soles) and liver damage. If you develop a severe allergic reaction, stop the medicine immediately and consult your doctor. Liver function has to be assessed regularly while on this medicine. The doctor might prescribe you vitamin B6 (pyridoxine) along with Solonex DT to prevent tingling and numbness.


Product Summary

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ContainsIsoniazid(100.0 Mg)
UsesActive and Latent Tuberculosis treatment, Prevention of tuberculosis in close contacts and individuals with human immunodeficiency virus infection.
Side effectsPeripheral neuropathy (tingling and numbness), Liver damage (jaundice), Loss of appetite, Nausea and Vomiting.
Check more medicines with composition as Isoniazid(100.0 Mg)

Uses of Solonex Dt 100 MG

  • Tuberculosis infection treatment

Contraindications of Solonex Dt 100 MG

  • If you are allergic to the medicine or any of its constituents (fever, chills, rashes or swelling of face and tongue after taking medicine).
  • If you have any liver disease or are suffering from liver infection(Hepatitis).
  • If you develop any serious side effects like fits(seizures) or visual disturbances from the medicine.

Side effects of Solonex Dt 100 MG

  • Peripheral neuropathy (tingling, burning sensation and numbness of hands and feet)
  • Loss of appetite
  • Nausea and vomiting
  • Stomach pain
  • Weakness and lethargy
  • Liver damage (jaundice, elevated liver enzymes)
  • Dizziness
  • Severe allergic reaction (fever, chills and rashes)
  • *The list does not include all the possible side effects. Consult your doctor if you develop any other symptoms or persistent symptoms while taking Solonex DT.

Precautions and Warnings of Solonex Dt 100 MG



Can I take Solonex DT during pregnancy?
Solonex DT is used cautiously in pregnancy to treat active tuberculosis infection. The medicine crosses the placenta (a pathway between the mother and the growing baby), and hence the newborn should be closely monitored for side effects if the mother has been prescribed the same. However, preventive treatment for tuberculosis should only be started after the female delivers to avoid the risk of exposure to the developing baby. There are no adequate studies and research about the effects of the medicine in pregnant females. Consult your doctor if you’re pregnant before starting the medicine.

Breast Feeding

Can I take Solonex DT while breastfeeding?
Nursing mothers can continue to breastfeed while on Solonex DT. Studies suggest that it gets excreted in breast milk in small quantities and does not produce any harmful effects in the newborn. The doctor should be informed if you are a nursing mother before starting it.


Can I drive if I have taken Solonex DT?
Solonex Dt can affect your driving ability; avoid driving if you are experiencing dizziness or visual difficulties.


Can I consume Solonex DT with alcohol?
Alcohol should not be consumed if you are on Solonex DT. The use of alcohol and Solonex DT increases the risk of liver damage. Consult your doctor for more details.

Other General Warnings

Talk to your doctor if
  • You develop any serious allergic reaction (fever, chills and swelling of face and tongue ) or any serious side effects (fits or visual disturbances) after taking the medicine
  • You’re suffering from liver disease or kidney disease
  • You are on long term medication for any medical health condition
  • You are a pregnant female or a nursing mother
  • You are consuming alcohol while on Solonex DT
  • You are diabetic

Mode of Action of Solonex Dt 100 MG

How Does It Work?

The medicine inhibits mycolic acid synthesis. Mycolic acid is a fatty acid that is a component of the cell wall of tuberculosis bacteria. It is primarily a tuberculocidal medicine. It kills both extra...
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Directions for Use of Solonex Dt 100 MG

  • The dose and duration of Solonex DT should be prescribed by the doctor.
  • Do not start the medicine without consulting a doctor.
  • The entire course of treatment should be taken to prevent the development of resistance (medicine becomes ineffective and difficult to treat infection in the future).
  • The medicine has to be taken orally on an empty stomach with a glass of water.
  • Do not chew or crush the medicine.
  • Preferably take medicine at the same time each day as prescribed.

Interactions of Solonex Dt 100 MG

Interactions with other medicines

  • Ketoconazole, Itraconazole: Antifungals (treats fungal infection)
  • Fluoxetine, Sertraline: Antidepressants (treats depression)
  • Theophylline (used in asthma)
  • Phenytoin, Valproate (treatment of fits)
  • *Solonex DT can modify the effect of the medicines listed above. Please inform your doctor if you are taking any medicine other than Solonex DT

Interactions with food items

  • Solonex DT should not be taken with food. Take medicine on an empty stomach. Avoid consuming tropical fish, red wine and cheese and medicine to avoid serious side effects. In case you develop headache...
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Storage and disposal of Solonex Dt 100 MG

Store at room temperature (20-25 degrees celsius) away from light and moisture. Keep it out of reach of children and pets. Expired medicines should be discarded properly.

Dosage of Solonex Dt 100 MG


In case you have overdosed, look for symptoms like nausea, vomiting, vision problems, slurring of speech, fits or breathing difficulties. Report to the emergency or call for medical help immediately i...
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Missed a Dose

In case you miss a dose, take the next dose as soon as you remember. If it's near the time of your next dose, skip the dose. Avoid doubling up the dose to catch up.

Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: I have been recently diagnosed as suffering from Tuberculosis infection; my physician has prescribed Solonex DT for the same. What are the possible long term side effects and warning signs of tablet?

A: Solonex DT is an anti-tubercular medicine. Tuberculosis is an infection of the lung caused by bacteria called mycobacterium tuberculosis. Medicine forms an essential component of all tuberculosis treatment regimens. It treats both active and latent tuberculosis infections. Your doctor can only start it. The possible long term side effects are tingling and numbness of hands and feet, jaundice, nausea and vomiting. If you develop fits(seizures) or visual disturbances, or rashes with swelling of the face, stop the medicine immediately and consult your doctor.

Q: I have been taking Solonex DT as prescribed for two months now. Can I stop the medicine as I have been noticing the yellowing of my eyes?

A: Yellowing of your eyes is probably due to jaundice which is a side effect of this medicine. The medicine should be continued for the duration prescribed by your doctor to prevent the development of resistance (Tuberculosis infection becomes difficult to treat in the future if the entire course of medicine is not completed). Jaundice, loss of appetite and tingling sensation of palms and soles are some of the common side effects of this medicine which should not let you stop the medicine. Consult your doctor for more information and evaluation of jaundice.

Q: My fourteen-year-old child recently got evaluated for cough and fever at a nearby DOTS centre. He received a BCG vaccination at the time of birth. Tests and chest X-Ray were suggestive of tuberculosis infection. The doctor has started him on Solonex DT along with other medicines.

A: If the sputum(cough) tests and chest X-ray are suggestive of tuberculosis infection as diagnosed by the doctor, the child needs to be started on anti-tubercular medicine immediately. It is possible that an individual can develop tuberculosis despite vaccination. Solonex DT is one of the constituents of all regimens against tuberculosis infection. Consult your doctor for more information.
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Last Updated on: 10 Feb 2022 | 07:02 PM (IST)
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