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Methycobal Injection 1ml

1ml Injection in Ampoule
MRP 130.30
114.6612% OFF
Inclusive of all taxes
30 days return policyRead More
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Methycobal 500 MCG/ML Description

Methycobal injection is used to treat vitamin B12 deficiency, anaemia and a painful nerve disease called peripheral neuropathy. It contains mecobalamin or methylcobalamin also known as vitamin B12. I

t helps in red blood cell formation, cell metabolism, nerve function and the production of DNA. This medicine will be given in the hospital by your doctor or nurse as an injection. Do not self-inject it. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting Methycobal injection.


Product Summary

Offer Price₹114.66
You Save₹15.64 (12% on MRP)
ContainsVitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin(500.0 Mcg/Ml)
UsesVitamin B12 deficiency
Side effectsPain and swelling at injection site, skin rash, itching
Check more medicines with composition as Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin(500.0 Mcg/Ml)

Uses of Methycobal 500 MCG/ML

Methycobal injection is used to treat vitamin B12 deficiency and megaloblastic anaemia (a blood disorder caused due to deficiency of vitamin B12). It is used in the treatment of painful nerve disease ...
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Contraindications of Methycobal 500 MCG/ML

  • If you are allergic to Mecobalamin or any other ingredients of Methycobal injection.
  • If you are suffering from any type of kidney disease.
  • If you have or have ever had Leber's hereditary optic neuropathy (slow, painless loss of vision, first in one eye and then in the other eye).

Side effects of Methycobal 500 MCG/ML

  • Pain and swelling at injection site
  • Skin rash
  • Itching
  • Swelling
  • Muscle cramps
  • Weakness
  • Dizziness
  • Difficulty in breathing
  • Diarrhoea
  • Headache

Precautions and Warnings of Methycobal 500 MCG/ML



Can I take Methycobal injection during pregnancy?
Your doctor may advise you oral supplements containing vitamin B12 and folic acid during pregnancy. Methycobal injection shall be given by your doctor in pregnancy only if essential. Safety in pregnancy is not known.

Breast Feeding

Can I take Methycobal injection while breastfeeding?
Components of the Methycobal injection pass into the breastmilk and is unlikely to harm a nursing infant when used in recommended doses. However, consult a doctor before using this injection while breastfeeding.


Can I drive if I have taken Methycobal injection?
Yes, you can drive if you don’t experience any side effects with Methycobal injection.


Can I consume alcohol with Methycobal injection?
Regular consumption of alcohol decreases vitamin B12 absorption from the gastrointestinal tract. Decreased vitamin B12 levels lead to Hence, it is better to avoid.

Other General Warnings

Talk to your doctor if
  • You have any existing medical condition like diabetes, hypertension, kidney or liver problem.
  • You are on other medications, supplements or following any complementary or integrative health approaches.
  • You have an eye disorder called Leber's hereditary optic neuropathy (slow and painless loss of vision).
  • You consume alcohol in excess regularly, your doctor may monitor your vitamin B12 levels to check the progress of treatment.
  • You develop an allergic reaction after taking the Methycobal injection.

Mode of Action of Methycobal 500 MCG/ML

How Does It Work?

Vitamin B12 is needed for the formation of red blood cells in the body and their growth. It helps in the absorption of folic acid and carbohydrates from food. It is essential for keeping our nerves he...
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Directions for Use of Methycobal 500 MCG/ML

  • Methycobal injection will be given to you as an injection by a doctor or nurse in a hospital or clinic.
  • Be careful of any instruction given during the administration and aftercare. Do not self inject.

Interactions of Methycobal 500 MCG/ML

Interactions with other medicines

  • Medicines like Aminosalicylic acid, Chloramphenicol, Colchicine, histamine-2 antagonists, Neomycin and proton pump inhibitors (e.g. Pantoprazole) can decrease the absorption of Mecobalamin.
  • Oral contraceptives can decrease the action of Mecobalamin by reducing its concentration in the body.
  • Folic acid when taken in a larger dose for a prolonged duration can impair the therapeutic response of Mecobalamin.
  • You should always tell the doctor if you are taking any other medicines, herbal preparation and supplements to avoid any interaction.

Storage and disposal of Methycobal 500 MCG/ML

  • Store Methycobal injection under the conditions mentioned on the pack.
  • Keep out of the reach of children and pets.
  • Do not keep the medicine when it is no longer needed or expired.

Dosage of Methycobal 500 MCG/ML


You are less likely to get an overdose of Methycobal injection as it is given to you by a doctor or nurse in a clinic or hospital. Please inform the doctor if you feel any discomfort immediately after...
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Missed a Dose

The chances of missing a dose of Methycobal injection are rare as you will be monitored closely by a healthcare professional. In case they happen to miss a dose, please inform them.

Content Details


Dr. Alok Nachane

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What is the difference between Mecobalamin and Methylcobalamin?

A: Both Methylcobalamin and Mecobalamin are the same. They contain cobalamin, which is a form of vitamin B12.

Q: Is Methycobal injection OTC medicine?

A: No, Methycobal injection has to be taken only under the supervision of a doctor. It is a prescription medicine.

Q: Can I take Methycobal tablets instead of injection?

A: Based on the severity of your disease or deficiency, your doctor shall prescribe you appropriate injection or tablet. In case of severe deficiencies, injection shall be given.

Q: What is the dosage of Methycobal Injection?

A: The dosage is based on your underlying medical condition, response to treatment and vitamin B12 tests report.

Q: What are the natural sources of vitamin B12?

  • Animal products such as fish, meat, poultry, eggs, milk and milk products contain vitamin B12 naturally
  • Plant foods do not contain vitamin B12 but fortified breakfast cereals are a source of vitamin B12 with high bioavailability for vegetarians
  • Some nutritional yeast products also contain vitamin B12

Q: Is vitamin B12 deficiency common in vegetarians?

A: Strict vegetarians are at a higher risk of developing vitamin B12 deficiency.

Q: What are the causes of vitamin B12 deficiency?

A: Vitamin B12 deficiency can be due to various reasons such as improper diet or diet deficient in vitamin B12, poor absorption from the intestine, certain disorders of intestine and surgeries which can impact absorption of this vitamin.

Q: How long does it take for vitamin B12 supplements to work?

  • Usually, it takes 48 to 72 hours for brisk production of new red blood cells
  • Once B12 reserves reach normal levels, injections can be taken every one to three months to prevent symptoms from returning

Q: Can low vitamin B12 cause weight gain?

A: There's hardly any evidence to suggest that it has any influence on weight gain or loss.

Q: What are the risk factors for vitamin B12 deficiency?

  • Certain prescription medications, including antacids and anti-diabetic medicines like metformin can cause vitamin B12 deficiency
  • An endocrine-related autoimmune disorder, such as thyroid disease or diabetes
  • Eating a vegetarian or vegan diet and excessive consumption of alcohol
  • Certain gastrointestinal disorders, such as Crohn’s disease or Gastric bypass surgery or removal of part of the stomach

Q: What are the complications of anaemia?

  • Brain related disorders such as anxiety, depression, irritability and even poor concentration and general restlessness
  • Heart and blood-related problems, increased risk of infections, improper growth in children and complication during pregnancy

Q: How can I prevent anaemia?

  • If you are a strict vegetarian, take vitamin B12 supplements.
  • If you have medical conditions like bleeding in the digestive tract, urinary tract or heavy menstrual bleeding, consult your doctor.
  • Include vitamin C, iron and vitamin B12 rich foods in the diet.
  • Avoid excessive intake of tea or coffee.

Q: Is Methycobal injection safe for diabetic patients?

A: Yes, it is safe for diabetic patients. However, it will be given only if prescribed by a doctor.

Q: Is there any side effect of the Methycobal injection?

A: Nausea, vomiting, diarrhoea, loss of appetite, headache, etc are a few common side effects of this injection. But these symptoms usually go away with time.

Q: How does the Methycobal injection be administered, iv or im?

A: Methycobal injection will be administered by a doctor or nurse in a healthcare setup. The doctor will decide the route of administration. Do not self-inject.

Q: When do you give methylcobalamin injection?

A: Methycobal injection is prescribed to treat vitamin B12 deficiency and megaloblastic anaemia (a blood disorder caused due to deficiency of vitamin B12). It is used in the treatment of painful nerve disease called peripheral neuropathy.

Q: Who should not take methylcobalamin?

A: You should not take Methycobal inj if you are allergic to mecobalamin or any other ingredients of methycobal injection, if you are suffering from any type of kidney disease or if you have or have ever had Leber's hereditary optic neuropathy.

Q: Can I take Methylcobal injection in sciatica pain?

A: Yes, you can use this injection for sciatica pain only if prescribed by a doctor. Sciatica pain is a type of nerve pain it can occur due to vitamin B12 deficiency. Do not self-medicate it.
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Last Updated on: 11 Apr 2022 | 08:58 AM (IST)

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