Pilocarpine

Molecule Description

Pilocarpine is a medicine which belongs to class of cholinergic agonists and mi

mics the action of a hormone called acetylcholine.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Pilocarpine

Mouth dryness (xerostomia) caused after radiation therapy in cancer Sjogren’s syndrome.

Contraindications of Pilocarpine

When should one not use Pilocarpine

Allergy to Pilocarpine
Uncontrolled asthma
Glaucoma
Eye infection
Eye inflammation

Side effects of Pilocarpine

Common side effects of this drug are:

Allergic reaction like- fever, chills, rash, hives, breathing difficulty, swelling over your face, lips, and throat
Irregular breathing or heartbeats, headache, chest pain, shaking, and vomiting
Increased tears or perspiration
Vision changes- blurred vision
Increased urination
Chilliness
Weakness
Flushing
Nausea
Runny nose
Dizziness

Precautions and Warnings of Pilocarpine

Pregnancy

Can I take Pilocarpine during pregnancy?

Do not take this medicine if you are pregnant or planning for pregnancy. It is unknown whether it harms the unborn baby. Hence a doctor’s discretion is necessary before you start this drug.

Breast Feeding

Can I take Pilocarpine while breastfeeding?

It is unknown if this medicine can pass into breast milk and harm the child. Do not breastfeed while you are on Pilocarpine.

Driving

Can I drive if I have consumed Pilocarpine?

Pilocarpine may cause blurring of vision. Do not drive while you are taking Pilocarpine.

Alcohol

Can I consume alcohol with Pilocarpine?

Pilocarpine may cause blurred vision as a side effect. This side effect may worsen with alcohol. Do not drink alcohol while you are on this medicine.

Other General Warnings

Talk to your doctor if

Lung problems (e.g., asthma, chronic bronchitis or chronic obstructive pulmonary disease)
Heart problems (e.g., heart failure, irregular pulse)
Gallbladder problems (e.g., gallstones)
Stomach problems (e.g., ulcers)
Liver problems (e.g., impaired liver function)
Nervous system problems/ mental problems
Kidney problems (e.g., renal insufficiency or kidney stones)
Eye problems (e.g., narrow-angle glaucoma)

Mode of Action of Pilocarpine

How Does It Work?

Pilocarpine acts by increasing the secretion of saliva in the mouth from the salivary glands, thereby reducing mouth dryness.

Interactions of Pilocarpine

Interactions with other medicines

Beta-blockers (Atenolol, Metoprolol). These may increase the heart-related side effects when taken along with Pilocarpine
Anticholinergic agents (Ipratropium, Atropine). These decrease the efficacy of Pilocarpine
Parasympathetic agents (Bethanechol). These increase the side effects of Pilocarpine

Interactions with food items

This medicine has interactions with alcohol.

Dosage of Pilocarpine

Overdose

Excess Pilocarpine ingestion may cause tremors, head pain, change in blood pressure, irregular heartbeat, breathing difficulty, confusion, vision changes, diarrhea, vomiting. Seek emergency medical at...

Missed a Dose

Take medicine as soon as you remember. If the missed dose falls at the time of your next scheduled dose, then skip it. Do not take an extra dose to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Abhishek B L

MBBS, MD (Pharmacology)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking Pilocarpine?

You must inform your doctor if you are suffering from any diseases of the heart, lungs, kidney, liver, and gallbladder
If you suffer from allergy of any kind
If you have any psychiatric condition
If you suffer from retinal detachment or an eye infection
Pilocarpine can interact with other drugs hence inform your doctor if you are taking any other medicines, supplements, or herbs. Also, tell your physician if you are stopping any medication

Q: When and how to consume the medicine?

You must take medicine precisely the way it is prescribed by the physician. Follow the instructions mentioned on the prescription label
Do not alter the dose unless recommended by your doctor
Do not take it longer or shorter than advised
The medicine can be taken with or without food
Drink more fluids when you are on pilocarpine treatment
It may take about 12 weeks for the drug to act

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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