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molecule

Trimethoprim

Molecule Description

Trimethoprim is an antibiotic that is used in the treatment of bacterial infect

ions. It belongs to the Sulfonamide group of medicines.

uses

Uses of Trimethoprim

  • Infections caused by Trimethoprim sensitive bacteria
  • Urinary tract infections (recurrent urinary tract infections)
  • Respiratory tract infections
contraindications

Contraindications of Trimethoprim

When should one not use Trimethoprim

  • Do not take if you are allergic to Trimethoprim or any ingredient of this medicine
  • Do not take this medicine in pregnancy
  • Do not take this medicine if you suffer from any blood disorders such as anaemia
  • Do not take this medicine for premature babies or infants under 4 months of age
sideEffects

Side effects of Trimethoprim

Common side effects of this drug are:

  • Hyperkalaemia (high levels of potassium in the blood)
  • Vomiting
  • Diarrhea
  • Nausea
  • Stomach discomfort
  • Skin rash
  • Oral ulcers
  • High potassium level – muscle weakness, slow heart rate, etc.
  • Headache
precautionsAndWarnings

Precautions and Warnings of Trimethoprim

pregnancy

Pregnancy

Q:
Can I take Trimethoprim during pregnancy?
A:
You should not take this medicine during pregnancy. It is harmful to the unborn baby.
breastfeeding

Breast Feeding

Q:
Can I take Trimethoprim while breastfeeding?
A:
It is probably unsafe to take this medicine if you are breastfeeding. This medicine passes into breast milk. However, it can be taken for a short duration if prescribed by the doctor.
driving

Driving

Q:
Can I drive if I have consumed Trimethoprim?
A:
No specific interaction has been reported yet.
alcohol

Alcohol

Q:
Can I consume alcohol with Trimethoprim?
A:
It is unsafe to consume alcohol with this medicine. It may lead to unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea and vomiting.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You have kidney problems, diabetes, folic acid deficiency (may cause anaemia), any disorder that causes skin sensitivity to light, pain attacks and muscle weakness
  • You are taking Repaglinide (medicine for treating diabetes), difficulty while urinating or a weak stream of urine, pain or swelling in your stomach area
  • You are taking any medicines including prescription medicines, non prescription medicines and herbal products
modeOfAction

Mode of Action of Trimethoprim

How Does It Work?

It kills and controls the growth of the bacteria by interfering with its Folic Acid metabolism.
interactions

Interactions of Trimethoprim

Interactions with other medicines

  • Repaglinide
  • Rifampicin
  • Digoxin
  • Phenytoin
  • Spironolactone
  • Bone marrow depressants
  • Pyrimethamine and Dapsone
  • Potassium supplements
  • Medicines used for the treatment of high blood pressure
  • Methotrexate
  • Procainamide
  • Diuretics
dosage

Dosage of Trimethoprim

Overdose

Seek emergency medical care if you happen to take an overdose of this medicine. Overdose symptoms include difficulty in breathing and uneasiness.

Missed a Dose

Take the next dose as soon as you remember; if the time for your next dose is close then skip it. Do not take a double dose if you have missed the dose.

Content Details

WRITTEN BY
doctor

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: What must be discussed with my doctor before I start the medication of Trimethoprim?

  • Tell your doctor if you have:
  • Heart problems
  • Kidney problems
  • Breathing problem like asthma
  • Diabetes – regular monitoring of blood glucose level
  • Have abnormally low levels of potassium (hypokalaemia), calcium (hypocalcaemia) or magnesium (hypomagnesaemia) in your blood
  • Have difficulties in passing urine or a weak stream of urine
  • Liver problems
  • In case you started to have pain or swelling in your stomach area
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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