Amitone Forte Tablets
Amitone Forte Tablets Description
Amitone Forte is a prescription medication used in the treatment of depression and associated anxiety. It is a combination of two drugs, Amitriptyline (25 mg) and Chlordiazepoxide (10 mg). Amitri
ptyline belongs to a class of medicines called tricyclic antidepressants, and Chlordiazepoxide is a benzodiazepine. The mode of action of Amitone Forte is by affecting multiple brain pathways that regulate mood, personality, and anxiety by targeting chemical messengers called neurotransmitters; hence their use as antidepressants. Depression is a mood disorder characterised by low mood, loss of interest in daily activities, difficulty sleeping, and other features. Anxiety is a condition associated with nervousness and constant thoughts of worry. These conditions are related to altered levels of neurotransmitters in the brain. Directions for use Amitone Forte should be strictly followed. The medication should be taken only after consulting a doctor. It should not be abruptly started or stopped. Taking the tablet at the same time every day is advisable. Side effects of Amitone Forte include constipation, urinary retention, dry mouth, orthostatic hypotension and dizziness, blurred vision, confusion, and increased appetite and weight gain.
Product Summary
Offer Price | ₹54.56 |
You Save | ₹7.44 (12% on MRP) |
Contains | Amitriptyline(25.0 Mg) + Chlordiazepoxide(10.0 Mg) |
Uses | Treatment of major depressive disorder with moderate to severe anxiety |
Side effects | Constipation, Urinary retention, Weight gain, Confusion, Orthostatic hypotension (sudden lowering of blood pressure on standing), Tiredness, Blurred vision, Dryness in mouth, Increased heart rate, Uncoordinated body movements, Memory impairment |
Therapy | ANTI-DEPRESSANT |
Uses of Amitone Forte Tablets
- Amitone Forte is used for the treatment of Major Depressive Disorder (MDD) associated with moderate to severe anxiety.
Contraindications of Amitone Forte Tablets
- Do not use Amitone Forte or use with caution:
- If you have hypersensitivity reactions to the active or inactive components of this medicine.
- If you have a history of heart conditions such as irregular heart rhythm or had a myocardial infarction (heart attack) recently.
- If you have an elective surgery planned; stop this medication before your surgery to avoid the risk of interaction with anaesthetic agents.
- If you have angle-closure glaucoma; do not use this medicine.
- If you have any epilepsy/seizure disorders; this medication decreases the seizure threshold; use cautiously.
- If you have any pulmonary diseases; use this medicine cautiously.
- If you are pregnant or planning a pregnancy.
- If you are under 24 years of age; this medication may increase suicidal ideation in this age group.
Side effects of Amitone Forte Tablets
- Side effects of Amitone Forte include:
- Constipation
- Urinary retention (difficulty in passing urine)
- Dry mouth
- Sudden lowering of blood pressure on standing up (orthostatic hypotension) and dizziness
- Blurred vision
- Confusion
- Increased appetite and weight gain
- Long-term use of benzodiazepines can cause tolerance and dependence.
Precautions and Warnings of Amitone Forte Tablets
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You should inform your doctor about any other medications you are taking. This tablet interacts with many other medications that use the same metabolic enzymes.
- You should report to your doctor immediately in case of any discomfort or sudden mood changes.
Mode of Action of Amitone Forte Tablets
How Does It Work?
Directions for Use of Amitone Forte Tablets
- This medication should be taken as prescribed by the treating physician.
- It is recommended to take this medication on a regular schedule. Taking the tablet at the same time every day is advisable to get optimal effects and reduce the chances of side effects.
- Swallow this medication as a whole. Do not crush, chew or break this tablet.
- It is recommended to finish the entire course of this medication as prescribed by the treating doctor. Abrupt stoppage of the drug can cause withdrawal side effects. Consult your doctor before stopping this medication....
- It can be taken with or without food.
- Driving or use of heavy machinery is not advised while using this medication.
- Inform your doctor regarding other medications you may be taking so they can check for potential interactions.
Interactions of Amitone Forte Tablets
Interactions with other medicines
- This medication affects the heart rhythm. It should not be used with other medications like astemizole and cisapride that also have the same effect. This may result in potentially life-threatening conditions. ...
- This medication should not be used concomitantly with MAOIs (Monoamine oxidase inhibitors) or within 14 days of the use of MAOIs and vice versa. Examples of MAOIs include selegiline and rasagiline.
- This medication should not be used with other medicines like isocarboxazid, which increases serotonin levels. This may result in a potentially fatal condition.
- This medication should not be used with other CNS depressants.
- This medication should not be mixed with other benzodiazepines.
Storage and disposal of Amitone Forte Tablets
Dosage of Amitone Forte Tablets
Overdose
Missed a Dose
Content Details
Dr. Bhavika Shah
MBBS, MD (Dermatology), DNB (Dermatology)
Frequently Asked Questions (FAQs)
Q: I have been using Amitone Forte tablets for a couple weeks now, but feel the same. Should I increase the dose?
Q: I have been using Amitone Forte tablets and feel better now. Can I stop taking it?
Q: I started taking Amitone Forte five days back. I am unable to sleep after taking the tablet. Should I stop taking it?
References
- Ahwazi HH, Abdijadid S. Chlordiazepoxide. (Updated 14 Nov 2021). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. Jan 2022 [cited 20 Feb 2022
- Thour A, Marwaha R. Amitriptyline. (Updated 29 July 2021). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. Jan 2022. [cited 20 Feb 2022]
- Limbitrol [Internet]. www.accessdata.fda.gov [cited 20 Feb 2022] -
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