Zidovudine

Molecule Description

Zidovudine is 'Nucleoside Reverse Transcriptase Inhibitor' (NRTI) type of antir

etroviral medicine. This medicine is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so that your immune system can work better.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Zidovudine

Treating HIV infection when used along with other medications
It is also used along with some other medication to help prevent women from passing HIV to the baby (foetus) during pregnancy

Contraindications of Zidovudine

When should one not use Zidovudine

Do not take this medicine if you are allergic to Zidovudine
Your white blood cell count and red blood cell count is meager

Side effects of Zidovudine

Common side effects of this drug are:

Headache
Nausea and vomiting
Loose motions
Pain in the stomach
Dizziness
Muscle pain

Precautions and Warnings of Zidovudine

Pregnancy

Can I take Zidovudine during pregnancy?

If this medicine is used in HIV positive pregnant women, it prevents passing HIV to the unborn baby. Regular investigations are necessary to monitor the growth of an unborn baby.

Breast Feeding

Can I take Zidovudine while breastfeeding?

HIV infection can pass through breast milk to the baby. Also, this medicine passes in breast milk, therefore avoid breastfeeding when on this medicine. Consult your doctor for advice.

Driving

Can I drive if I have consumed Zidovudine?

Zidovudine can cause dizziness and decreased alertness, therefore avoid driving when you are on this medication.

Alcohol

Can I consume alcohol with Zidovudine?

Alcohol can have an ill effect on bones when on this medication, therefore, avoid drinking alcohol.

Other General Warnings

Talk to your doctor if

You have liver disease, or your weight is more than average.

Mode of Action of Zidovudine

How Does It Work?

It works by blocking the multiplication of HIV by inhibiting specific mechanisms at the level of viral RNA.

Interactions of Zidovudine

Interactions with other medicines

Medicines which suppress bone marrow such as Ganciclovir, Dapsone, Trimethoprim
Medicines that may affect the kidneys (including NSAIDs such as Ibuprofen or Naproxen)
Lorazepam, Sulfamethoxazole/ Trimethoprim, Lamivudine, Rosuvastatin and Duloxetine

Interactions with food items

Continue your regular diet unless your doctor tells you to follow any particular diet.

Dietary Restrictions of Zidovudine

No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for further details.

Dosage of Zidovudine

Overdose

Symptoms of overdose are extreme drowsiness, tiredness, headache and confusion. Consult with your doctor as soon as possible.

Missed a Dose

It would be best if you took the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose, but do not take extra medicine to make up for the skipped ...

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should be discussed with my healthcare provider before taking Zidovudine?

Tell your doctor if you have any of the medical conditions:
If you have any history of allergy to medicine, food
If you have bone marrow problems (e.g. low white blood cell or haemoglobin levels) or lactic acidosis
If you have a history of alcohol abuse or dependence, kidney problems, pancreatitis or Hepatitis C Virus (HCV) infection or other liver problems (e.g., cirrhosis)
If you are on dialysis, you are at risk for liver problems or you are very overweight

Q: Should Zidovudine be taken on an empty stomach?

A: Take Zidovudine with food as this increases the absorption of the medication into the body and enhances the efficiency of it.

Q: Are any lab tests required during this medication?

A: During treatment and for at least five to six months after stopping this medicine, regular blood tests are needed to monitor your liver function and blood cell count in your blood.

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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