Anti Nuclear Antibody (ANA-Elisa) Test In Pune - Price & Details

The antinuclear antibody (ANA-Elisa) test is a blood test used to detect antinuclear antibodies, which may be associated with certain autoimmune conditions. Normally, the immune system protects the body from infections while recognising the body’s own healthy cells and tissues. Sometimes, this immune response becomes misdirected and attacks healthy tissues, a process known as autoimmunity. The antibodies produced against the body’s own tissues are called autoantibodies. Antinuclear antibodies (ANA) are a type of autoantibody that targets substances inside the nucleus of cells. ANA may be associated with conditions such as systemic lupus erythematosus (SLE), Sjögren syndrome, and systemic sclerosis. Your doctor may advise an ANA-Elisa test when symptoms such as persistent fatigue, joint or muscle pain, swelling, unexplained fever, or skin rashes suggest a possible autoimmune condition. The test requires a blood sample and usually does not require fasting or any special preparation unless advised otherwise by your doctor. Your ANA-Elisa result is interpreted along with your symptoms, medical history, and other test findings. This test does not identify the specific type of autoimmune condition. Hence, your doctor may recommend specific autoimmune testing if the result of your ANA-Elisa test is positive.

The ANA-Elisa test may be recommended when your symptoms do not have another clear explanation or when your medical history and examination suggest a possible autoimmune condition. Your doctor may recommend this test when there are signs or symptoms such as:

• Persistent or unexplained fatigue
• Joint pain, stiffness, or swelling
• Muscle pain or weakness
• Recurrent fever
• Unexplained skin rashes, blisters, or changes in skin colour
• Swelling of the salivary glands, with dry mouth or dry eyes
• Symptoms affecting multiple parts of the body
• Unexplained abdominal pain
• Unexplained hair loss
• Increased sensitivity to sunlight
• Fingers or toes that turn unusually pale, blue, or red, especially in cold weather

Note: ANA testing is not usually recommended as a routine screening test for people without symptoms suggestive of an autoimmune disorder. This is because antinuclear antibodies can also be found in some healthy people, so a positive result does not necessarily mean that you have an autoimmune disease.

The ANA-Elisa test can help doctors evaluate certain autoimmune and connective tissue diseases. ANA is commonly associated with conditions such as:

• Systemic lupus erythematosus (SLE): A long-term autoimmune disease that can affect several parts of the body, including the joints, skin, kidneys, heart, lungs, blood vessels, and nervous system.
• Sjögren syndrome: An autoimmune condition that commonly affects the glands that produce tears and saliva, causing dry eyes and dry mouth.
• Scleroderma (systemic sclerosis): An autoimmune condition that can cause changes in the skin and may affect blood vessels and internal organs.
• Inflammatory muscle diseases (myositis): A group of conditions that can cause inflammation and weakness of the muscles.
• Rheumatoid arthritis: An autoimmune condition that mainly affects the joints, causing pain, stiffness, and swelling.
• Psoriatic arthritis: An inflammatory condition that can cause joint pain, stiffness and swelling in people with psoriasis.
• Autoimmune hepatitis: A condition in which the immune system attacks the liver, causing inflammation.
• Autoimmune thyroid diseases: Conditions in which the immune system attacks the thyroid gland and may affect thyroid hormone production.

Note: ANA is not specific to any one disease and cannot diagnose these conditions on its own. A positive ANA result may also occur in some healthy people and in certain other conditions. Doctors interpret the result along with your symptoms, medical history, examination, and other test results.

What to Expect Before the ANA-Elisa Test?

• You may eat and drink normally before the ANA-Elisa test.
• The ANA-Elisa test can be performed at any time of day.
• The ANA-Elisa test results may be affected by medications, supplements, and recent bacterial or viral illnesses. Inform your doctor regarding these.

What to Expect During the Blood Collection?

• A trained phlebotomist from PharmEasy will arrive at your home at the scheduled time.
• They will take a blood sample from a vein in your arm using a small needle.
• After the needle is inserted, a small amount of blood will be collected into a test tube or vial.
• You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

What to Expect After the ANA-Elisa Test?

• Mild throbbing may be felt at the blood collection site after the blood is drawn, which should improve in a few minutes.
• Occasionally, you may feel dizzy, in which case you may lie down for a while until the feeling passes.

Note: If you notice anything unusual at the puncture site, such as persistent bleeding, a rash, or pain, consult your healthcare provider.

The ANA-Elisa test measures antinuclear antibodies (ANA) in your blood using the enzyme-linked immunosorbent assay (ELISA) method. The result is reported as an OD (optical density) ratio.

The reference range and cut-off values may vary depending on the laboratory and the testing method used. Your ANA-Elisa report will include the applicable reference range for interpreting your result.

A positive ANA result is not specific to any one condition. ANA may also be found in some healthy individuals, particularly older adults, as well as in certain infections, malignancies, and drug-induced autoimmune conditions. The final diagnosis is made by a doctor based on the overall clinical picture, and other relevant investigations.

Potential Risks and Complications

• The ANA-Elisa test is generally safe and involves minimal risk.
• Mild discomfort, slight bleeding, or bruising at the blood collection site, dizziness, or light-headedness may occasionally occur.
• In rare cases, there may be difficulty locating a vein or a small risk of infection.

Understanding ANA-Elisa Test Limitations

• A positive ANA result occurs in about 30% of healthy people. It can also occur in some infections, cancers, or certain medication use. Hence, a positive result does not always mean you have an autoimmune disorder.
• Some autoimmune conditions do not produce a positive ANA result.
• Sometimes in the early stages of an autoimmune disease, detectable levels of ANA are not yet present, so the test may give a false-negative result.
• Since ANA is not specific to an autoimmune disorder, if your ANA-Elisa test result is positive, you may be advised additional tests specific to particular autoimmune disorders.
• Results may vary between laboratories due to differences in testing methods and procedures.
• Certain medicines, high-dose biotin, or problems with the blood sample may also affect the result.

The ANA-Elisa test is priced at around ₹449, though the exact cost can vary based on your location in Pune and available offers. To better understand the pricing differences, you can compare the ANA-Elisa test costs across major cities in India.

You can book the Anti Nuclear Antibody (ANA-Elisa)Test in Pune through PharmEasy with convenient home sample collection across several localities, including :

• Kothrud
• Shivajinagar
• Baner
• Aundh
• Pashan
• Wagholi
• Karve Nagar
• Warje
• Sinhagad Road
• Viman Nagar
• Lohegaon
• Kalyani Nagar
• Koregaon Park
• Hadapsar
• Mundhwa
• Kharadi
• Hinjewadi
• Nigdi
• Pimple Saudagar
• Dhankawadi

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