Anti Nuclear Antibody (ANA-Elisa) Test In Delhi - Price & Details

The antinuclear antibody test (ANA-Elisa test) is a blood test used to check for antinuclear antibodies, which are autoantibodies that mistakenly target the nucleus of the body’s own cells instead of harmful invaders. Since the nucleus functions as the cell’s command centre, this misdirected immune response can trigger inflammation and tissue damage across various organs. ANA testing is used in the diagnostic evaluation of various autoimmune diseases, including connective tissue diseases such as systemic lupus erythematosus (SLE), Sjögren syndrome, and systemic sclerosis. The ELISA method specifically screens for these antibodies using an enzyme-based reaction, offering a reliable first step in autoimmune disease evaluation. Doctors typically recommend this test for individuals experiencing unexplained symptoms such as persistent joint pain, fatigue, skin rashes, or fever, particularly when an autoimmune condition is suspected. However, ANA testing cannot diagnose an autoimmune disorder on its own; doctors consider the result alongside symptoms, physical examination, and other laboratory tests to reach a diagnosis. A positive result often leads to further specific testing to pinpoint the exact autoimmune condition involved. The test requires a simple blood draw, typically from a vein in the arm, and needs no fasting or any special preparation beforehand.

The ANA-Elisa test may be recommended when your symptoms do not have another clear explanation or when your medical history and examination suggest a possible autoimmune condition. Your doctor may recommend this test when there are signs or symptoms such as:

• Persistent or unexplained fatigue
• Joint pain, stiffness, or swelling
• Muscle pain or weakness
• Recurrent fever
• Unexplained skin rashes, blisters, or changes in skin colour
• Swelling of the salivary glands, with dry mouth or dry eyes
• Symptoms affecting multiple parts of the body
• Unexplained abdominal pain
• Unexplained hair loss
• Increased sensitivity to sunlight
• Fingers or toes that turn unusually pale, blue, or red, especially in cold weather

Note: ANA testing is not usually recommended as a routine screening test for people without symptoms suggestive of an autoimmune disorder. This is because antinuclear antibodies can also be found in some healthy people, so a positive result does not necessarily mean that you have an autoimmune disease.

The ANA-Elisa test can help doctors evaluate certain autoimmune and connective tissue diseases. ANA is commonly associated with conditions such as:

• Systemic lupus erythematosus (SLE): A long-term autoimmune disease that can affect several parts of the body, including the joints, skin, kidneys, heart, lungs, blood vessels, and nervous system.
• Sjögren syndrome: An autoimmune condition that commonly affects the glands that produce tears and saliva, causing dry eyes and dry mouth.
• Scleroderma (systemic sclerosis): An autoimmune condition that can cause changes in the skin and may affect blood vessels and internal organs.
• Inflammatory muscle diseases (myositis): A group of conditions that can cause inflammation and weakness of the muscles.
• Rheumatoid arthritis: An autoimmune condition that mainly affects the joints, causing pain, stiffness, and swelling.
• Psoriatic arthritis: An inflammatory condition that can cause joint pain, stiffness, and swelling in people with psoriasis.
• Autoimmune hepatitis: A condition in which the immune system attacks the liver, causing inflammation.
• Autoimmune thyroid diseases: Conditions in which the immune system attacks the thyroid gland and may affect thyroid hormone production.

Note: ANA is not specific to any one disease and cannot diagnose these conditions on its own. A positive ANA result may also occur in some healthy people and in certain other conditions. Doctors interpret the result along with your symptoms, medical history, examination, and other test results.

What to Expect Before the ANA-Elisa Test?

• You can eat and drink normally before the test.
• The blood sample for this test can be taken at any time of day.
• Let your physician know about all the medicines and supplements you take and if you have recently been ill, especially if you had any bacterial or viral illnesses, as these can affect test results.

What to Expect During the Blood Collection?

• This test involves collecting a blood sample.
• A phlebotomist will insert a sterile (IV) needle into a vein (usually a vein in your arm) and fill one or more test tubes with blood.
• A slight sting may be felt when the needle is inserted and removed.

What to Expect After the ANA-Elisa Test?

• Mild throbbing at the site may be felt after the blood is drawn, which will pass in a few moments.
• Once the sample is analysed in the laboratory, the test reports will be uploaded to the PharmEasy platform after review by a medical practitioner.
• The report can be downloaded to your device from the comfort of your home.

Note: If you notice anything unusual at the puncture site, such as persistent bleeding, a rash, or pain, consult your healthcare provider.

The ANA-Elisa test measures antinuclear antibodies (ANA) in your blood using the enzyme-linked immunosorbent assay (ELISA) method. The result is reported as an OD (optical density) ratio.

The reference range and cut-off values may vary depending on the laboratory and the testing method used. Your ANA-Elisa report will include the applicable reference range for interpreting your result.

A positive ANA result is not specific to any one condition. ANA may also be found in some healthy individuals, particularly older adults, as well as in certain infections, malignancies and drug-induced autoimmune conditions. The final diagnosis is made by a doctor based on the overall clinical picture and other relevant investigations.

Potential Risks and Complications

• Minor risks involved with a blood draw may occasionally occur, such as mild pain, slight bleeding, bruising, dizziness, or light-headedness. Rarely, vein access may be difficult.
• Medical attention should be sought if persistent bleeding, swelling, redness, or severe pain develops.

Understanding ANA-Elisa Test Limitations

• A positive ANA does not necessarily mean you have an autoimmune disease. ANA may also be detected in healthy individuals and can occur with certain infections, cancers, and other conditions.
• ANA is sensitive but has limited specificity. Positive results can occur in people without autoimmune disease, particularly when testing is performed without relevant symptoms.
• A negative ANA does not exclude every autoimmune disorder. Conditions such as rheumatoid arthritis, inflammatory muscle diseases, and some forms of vasculitis can occur despite a negative ANA.
• ANA results are not interpreted in isolation. Your doctor will consider your symptoms, medical history, physical examination, and other tests, such as a CBC, urinalysis, and disease-specific investigations.
• ANA does not determine the exact autoimmune condition. If ANA is positive, your doctor may suggest more specific antibody tests based on your symptoms and clinical findings.

The ANA-Elisa test is priced at around ₹449, though the exact cost can vary based on your location in Delhi and available offers. To better understand the pricing differences, you can compare the ANA-Elisa test costs across major cities in India.

You can book the Anti Nuclear Antibody (ANA-Elisa)Test in Delhi through PharmEasy with convenient home sample collection across several localities, including:

• Dwarka
• Vasant Kunj
• Saket
• Chhattarpur
• Greater Kailash
• Lajpat Nagar
• South Extension
• East of Kailash
• Green Park
• Janakpuri
• Rajouri Garden
• Paschim Vihar
• Punjabi Bagh
• Rohini
• Pitampura
• Preet Vihar
• Mayur Vihar
• Karol Bagh
• Connaught Place
• Civil Lines

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