Introduction: 

Punarnavadi Mandoor is a polyherbal formulation that is rich in iron. It is an effective iron supplement mentioned in Ayurvedic Samhitas. Punarnava Mandoor is generally available in tablets and is mainly used to treat iron deficiency anaemia. The principal constituent of the formulation is Punarnava itself, a herb named Boerhavia Diffusa, with immense medicinal qualities. ¹ 

Sixteen different herbal ingredients are used to prepare Punarnavadi Mandoor namely, mandoor, iron oxide (ferric oxide) and gomutra (cow’s urine). The herbs that are used in the preparation are – punarnava, trivrut, shunti, vidanga, devdaru, chitrak, kustha, haridra, amalaki, bibhitaki, haritaki, danti, chavya, kutaki, musta, and pippalimula.¹ 

Therapeutic Uses of Punarnavadi Mandoor: 

Punarnavadi Mandoor has been in use since the inception of the Ayurvedic traditions. Ayurvedic medicine is one of the world’s oldest comprehensive therapies. Ayurvedic formulations are prescribed for various ailments to either manage their symptoms or improve health quality. Some of the significant properties of the formulation are its anti-inflammatory, diuretic, blood purifying, haematogenic and haematinic activities.^1,2 

Some of the therapeutic qualities of the ingredients of the Punarnavadi Mandoor are: 

Punarnava 

• Diuretic 
• Anti-inflammatory¹ 

Chitrak 

• Liver protective 
• Kidney protective¹ 

Danti 

• Blood purifier 
• Anti-inflammatory 
• Analgesic¹ 

Devdaru 

• Anthelminthic¹ 

Haridra 

• Anti-inflammatory 
• Hypoglycemic¹ 

Pippalimula 

• Liver protective 
• Antioxidant¹ 

Musta 

• Antipyretic¹ 

Kutaja 

• Arshoghna (relieves haemorrhoids) 
• Kandughna (relieves itching) 
• Stanyashodhana (Detoxifies and cleanses breast milk)¹ 

Suntha 

• Anti-inflammatory¹ 

Triphala 

• Longevity 
• Antibacterial 
• Antiviral¹ 

Trivrut 

• Anti-inflammatory 
• Antimicrobial 
• Liver protective 
• Laxative 
• Purgative¹ 

Vidanga 

• Anti-parasitic 
• Blood purifier¹ 

Mandoor 

• Iron source¹ 

Gomutra 

• Anti-bacterial¹ 

Punarnavadi mandoor is one of the Kharaliya Rasayan. Kharaliya Rasayan is known to have a long shelf life with increased treatment efficacy, decreased dose and duration in which it is used. Punarnavadi mandoor is an Ayurvedic medicine that is useful for multiple health conditions. It helps in decreasing cholesterol, creatinine and urea, improves blood quality and count, and removes toxins from the blood.

Dr. Siddharth Gupta, MD

Benefits of Punarnavadi Mandoor: 

1. Benefits of Punarnavadi Mandoor for Iron Deficiency Anaemia: 

• Anaemia is a condition commonly caused due to an iron deficiency, and the state leads to reduced haemoglobin in the blood.
• Punarnavadi Mandoor is an excellent remedy to increase the iron levels in the body.
• It helps to reduce iron deficiency by improving the levels of ferritin.
• Ferritin is a protein that helps to store iron in the body. ¹ 

2. Benefits of Punarnavadi Mandoor for Liver: 

• Fatty liver disease is one of the most common liver diseases.
• It is caused due to excess storage of fat in the liver. 
• Punarnavadi Mandoor is one of the ayurvedic remedies that can reduce fat accumulation in the liver.
• It reduces the accumulation of fat, improves liver functions, and induces the regeneration of liver cells.¹ 

3. Benefits of Punarnavadi Mandoor for Ascites (Fluid Accumulation): 

• Ascites is a condition of excess fluid accumulation in the body’s cavities.
• Punarnavadi Mandoor can reduce the fluids in the body by increasing urine output without losing vital electrolytes from the body.¹ 

4. Benefits of Punarnavadi Mandoor for Skin: 

• Skin infections or blemishes may be related to impurities in the blood.
• Detoxifying the blood is considered to be the best solution to improve skin health as per Ayurveda.
• Punarnavadi Mandoor is one of the Ayurvedic remedies that can remove toxins from the blood and purify it, making it is very beneficial for improving skin health.¹  

5. Benefits of Punarnavadi Mandoor for Kidney: 

• Punarnavadi Mandoor is an excellent Ayurvedic preparation to improve blood counts in kidney patients.
• In addition to this, it can also purify and improve the quality of blood.¹
• Punarnavadi Mandoor can also help decrease the levels of urea, creatinine, and cholesterol.
• For better results, it may be prescribed in combination with Mutrakrichhantak churna for patients with kidney failure.² 

Also Read: Karela Jamun Juice Benefits: A Research-Based Guide to its Health Wonders

6. Punarnavadi Mandoor for Geriatric Anaemia (Anaemia in Old Age): 

• Anaemia is a prevalent ailment most of our elderly face today.
• The condition increases the risk of weakness leading to poor quality of life.
• The ingredients of Punarnavadi Mandoor work together to reduce iron deficiency anaemia in the elderly. 
• Mandoor Bhasma acts as the iron supplement in Punarnavadi Mandoor, and the herb Amalaki promotes its absorption in the body.
• The other herbs also improve absorption by enhancing appetite and digestion power.³ 

7. Benefits of Punarnavadi Mandoor for Stress: 

• Punarnavadi Mandoor is proven to possess anti-stress activity in laboratory studies.
• Once further investigations are done in humans, we could use this ayurvedic preparation to control stress.⁴ 

8. Benefits of Punarnavadi Mandoor for Deep Vein Thrombosis: 

• Deep Vein Thrombosis (DVT) is a common problem in people with coagulation disorders.
• It manifests as the formation of blood clots in the veins of the legs.
• Punarnavadi Mandoor is one of the ayurvedic formulations found to be very beneficial in reducing the coagulation process and managing the symptoms of DVT.
• Punarnavadi Mandoor acts on the clotting factors by purifying the blood and reducing inflammation.⁵ 

Punarnavadi mandoor is famous in Unani medicine too. It is used as an appetizer, as a reliever in joint pain and ophthalmia, keeps infections away, is an expectorant, relieves flatulence and is a reliable blood purifier.

Dr. Rajeev Singh, BAMS

Also Read: Ginger – Uses, Benefits, Side Effects & Precautions

How to Use Punarnavadi Mandoor? 

Punarnavadi Mandoor is usually prescribed to be taken orally by your Ayurvedic physician.  

1. Punarnavadi Mandoor tablets¹ 
2. Punarnavadi Mandoor with buttermilk to enhance its efficacy ¹ 

Your Ayurvedic physician will prescribe you the form and dosage as per your health condition. 

Also Read: Vidarikan – Uses, Benefits, Side Effects & Precautions

Side Effects of Punarnavadi Mandoor: 

One of the documented side effects of Punarnavadi Mandoor is 

• Drug-induced liver injury.⁶ 

Precautions to Take with Punarnavadi Mandoor:  

• Punarnavadi Mandoor should not be taken if you are pregnant or breastfeeding.  
• Punarnavadi Mandoor may be used in Garbhini Pandu (iron deficiency during pregnancy). 
• However, do not take it without consulting your Ayurvedic physician.²   

Also Read: Nirguni – Uses, Benefits, Side Effects & Precautions

Frequently Asked Questions (FAQs) : 

Also Read: Hing – Uses, Benefits & Side Effects

References: 

1. Pusam P, Bhise DD, Gupta SL, Wadodkar DS, Scholar PG, Professor A, et al. A DETAILED CONCEPT OF PUNARNAVA MANDUR. European Journal of Biomedical And Pharmaceutical Sciences [Internet]. 2018 Feb [cited 2022 Feb 25];5(4). Available from: https://storage.googleapis.com/journal-uploads/ejbps/article_issue/volume_5_april_issue_4/1522488021.pdf  

2. Balajirao Kachare B, Gupta SL, Chavan S, Lodhe S, Shaha P, Scholar P, et al. A REVIEW ON PUNARNAVADI MANDUR. World Journal of Pharmaceutical Research [Internet]. 2019 [cited 2022 Feb 25];8(11). Available from: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1569832726.pdf  

3. Megha G. Pandya, Alankruta R. Dave. A clinical study of Punarnava Mandura in the management of Pandu Roga in old age (geriatric anemia). 2014 [cited 2022 Feb 25];35(3). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649575/pdf/AYU-35-252.pdf  

4. Gour R. Boerhaavia Diffusa Linn Plant: A Review-One Plant with Many Therapeutic Uses. Int Journal of Pharmaceutical Sciences and Medicine (IJPSM) [Internet]. 2021 Apr [cited 2022 Feb 26];6:25–41. Available from: https://ijpsm.com/Publish/Apr2021/V6I403.pdf  

5. Dr. Pusuluri YVSM Krishna, Wasedar Vishwanath S, Dani Harshikha. Effect of Punarnavadi Mandoor and Shiva Gutika in Acute Deep Vein Thrombosis – A Case Report | Journal of Ayurveda and Integrated Medical Sciences. Journal of Ayurveda and Integrated Medical Sciences [Internet]. 2017 [cited 2022 Feb 23]; Available from: https://www.jaims.in/jaims/article/view/284  

6. Dalal KK, Holdbrook T, Peikin SR. CASE REPORT Ayurvedic drug induced liver injury. World Journal of hepatology [Internet]. 2017 Nov [cited 2022 Feb 25];9(31). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680208/pdf/WJH-9-1205.pdf  

7. Pahwa P, Kotwal S. A CASE STUDY ON THE AYURVEDIC MANAGEMENT OF PRIMARY OPTIC ATROPHY. World Journal of Pharmaceutical Research [Internet]. 2018 [cited 2022 Feb 25];7:679. Available from: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1527757551.pdf  

Also Read: Munakka – Uses, Benefits & Side Effects

 Disclaimer:

The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.