Linezolid
Molecule Description
Linezolid is an antibiotic of the Oxazolidinones group that works by stopping t
he growth of certain bacteria that cause infections.
Uses of Linezolid
- Pneumonia
- Skin infections
- Bacterial infections as per doctor’s discretion
Contraindications of Linezolid
When should one not use Linezolid
- If you are allergic to Linezolid
- If you are taking medicines called Monoamine Oxidase Inhibitors (MAOI) like Phenelzine, Isocarboxazid, Selegiline, Moclobemide or have taken these within the last two weeks
- If you are breastfeeding
- Kidney or liver disease
Side effects of Linezolid
Common side effects of this drug are:
- Nausea, vomiting
- Stomach pain
- Diarrhea - bloody or watery
- Vaginal itching or discharge
- Constipation
- Headache, dizziness
- Skin rash, itching
- Allergy – facial swelling, difficulty in breathing (serious)
- Anemia
- Vision disturbances- blurred vision, change in colour vision
- Bleeding from nose, mouth, etc.
- Easy bruising
- Fits (uncommon)
Precautions and Warnings of Linezolid
Pregnancy
Q:
Can I take Linezolid during pregnancy?
A:
There are no adverse effects noted while using Linezolid during pregnancy. But scientific data on absolute safety of it in pregnancy is sparse. Hence, risk cannot be ruled out. It is better to inform your doctor if you are pregnant or planning a pregnancy.
Breast Feeding
Q:
Can I take Linezolid while breastfeeding?
A:
Do not breastfeed when taking Linezolid because it passes into breast milk and could affect the baby.
Driving
Q:
Can I drive if I have consumed Linezolid?
A:
Linezolid can lead to dizziness and vision problems. If this happens, do not drive.
Alcohol
Q:
Can I consume alcohol with Linezolid?
A:
Avoid drinking alcohol, especially draught beers and wine as it can cause an increase in blood pressure.
Other General Warnings
Talk to your doctor if
- You have bruise and bleed easily
- You are anaemic
- You have a history of fits
- You have liver problems or kidney problems or undergoing dialysis
- You have diarrhoea
- Visual disturbances like blurred vision, changes in colour vision, difficulty in seeing detail or if your field of view becomes restricted
- If you develop diarrhea while taking Linezolid. If this becomes persistent or you notice blood or mucus in stools, immediately stop taking Linezolid and consult your doctor
Mode of Action of Linezolid
How Does It Work?
Linezolid controls infection by killing the bacteria.
Interactions of Linezolid
Interactions with other medicines
Tell your doctor if you are taking or have taken within the last two weeks the following medicines: Monoamine Oxidase Inhibitors ( MAOIs, e.g. Phenelzine, Isocarboxazid, Selegiline, Moclobemide). These may be used to treat depression or Parkinson’s disease, glaucoma medicines, medicines that can raise blood pressure, e.g., Levodopa or diet pills, stimulants, or ADHD medications, cough or cold medication (Pseudoephedrine or Phenylpropanolamine) and Rifampicin, certain antidepressants known as Tricyclics or SSRIs (Selective Serotonin Reuptake Inhibitors). There are many of these including Amitriptyline, Citalopram, Clomipramine, Dosulepin, Doxepin, Fluoxetine, Fluvoxamine, Imipramine, Lofepramine, Paroxetine, Sertralin....
Interactions with food items
Avoid eating large amounts of cheese, yeast extracts or soya bean extracts e.g. soy sauce. It is because Linezolid may react with a substance called Tyramine which is naturally present in some foods. This interaction may cause an increase in your blood pressure....
Dietary Restrictions of Linezolid
No information is available on dietary restrictions while you are taking Linezolid, consult your doctor or pharmacist for further information.
Dosage of Linezolid
Overdose
If you happen to take an overdose of the medicine, kindly seek emergency medical care immediately. The effects of an overdose may be lethal and need immediate medical attention. Overdose symptoms may be – nose or mouth bleeding, etc. easy bruising, vertigo, etc....
Missed a Dose
Take the forgotten tablet as early as you remember. Take the next pill 12 hours after this and continue taking your tablets every 12 hours.
Content Details
WRITTEN BY
Dr. Mahesh Muthe
MBBS
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: When and how to consume the medicine?
A: Linezolid should be taken in the exact dose as advised by the physician. The liquid medicine should be measured in a measuring device and then consumed and should not be taken on approximate measurements. Shake the oral suspension before every use. Do not take more than the recommended dosage of this medicine. Overdose of Linezolid can cause serious problems. Take Linezolid with a full glass of water. Drink plenty of liquids to prevent dehydration. Complete the full course of treatment as advised by the doctor. You will start feeling better within the first few doses but do not stop the medicine in between.
Q: What should I discuss with my healthcare expert before taking Linezolid?
A: Inform the doctor about your detailed medical and surgical history. Inform your physician if you have any kidney or liver disease, adrenal gland tumor, weak immune system, high blood pressure, epilepsy or a history of seizures or stroke, bone marrow suppression, mental illness or diabetes.
References
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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