Naxdom 250 Tablet
15 Tablet(s) in Strip
Product Summary
Naxdom 250 mg Tablet contains domperidone 10 mg and naproxen 250 mg and is used to treat migraine attacks with nausea or vomiting. Naproxen reduces pain-producing inflammatory chemicals in this Sun Pharma combination. Domperidone helps control the nausea and vomiting associated with migraine.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 4:43 PM (IST)
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Dose Form
TABLET
Expiry
General Information
| Therapy | Migraine drugs |
| Composition | Domperidone(10.0 Mg)+Naproxen(250.0 Mg) Domperidone 10.0 Mg+Naproxen 250.0 Mg |
Domperidone 10.0 Mg+Naproxen 250.0 Mg
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*Offer applicable on orders above ₹1000About Naxdom
Naxdom Tablet is an anti-migraine medicine. It contains a combination of naproxen and domperidone as active substances. Naproxen is an anti-inflammatory medicine, while domperidone is an anti-emetic agent. It is used in the treatment of migraine headaches. It is also used in inflammatory (pain and swelling) conditions of the joints like rheumatoid arthritis and other forms of arthritis. It works by blocking the effect of inflammation-causing substances and producing relief in symptoms. This medicine also controls nausea and vomiting. Avoid taking this medicine if you have a heart rhythm problem or history of ulcers due to pain killers. Long-term treatment with this medicine can affect your liver and kidneys. Take this medicine as suggested by the doctor and in the dose and duration prescribed. Before using this medicine, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history. This medicine should not be used in children below 5 years of age.
Uses
- Naxdom Tablet is used to relieve pain, swelling, and discomfort associated with different forms of arthritis and other conditions.
- It is also used to prevent migraine (intense headaches with nausea, vomiting, and sensitivity to light and sound).
Contraindications
- If you are allergic to naproxen, domperidone, or any other ingredients of Naxdom Tablet.
- If you have an allergy to painkillers like aspirin or ibuprofen. If you are not sure what these medicines are, please confirm with your doctor.
- If you have a history of ulcers or bleeding.
- If you have any problems with your heart, liver, or kidney.
- If you're pregnant or think you may be pregnant or breastfeeding.
- If you have a pituitary gland tumour that releases an excess of prolactin hormone (prolactinoma).
- If you have an obstruction, blockage, or perforation (tear) in the intestine or any part of the gut.
- If you have any condition due to which there is a salt imbalance in your body (low levels of potassium or magnesium or high level of potassium).
Side effects
- Headache
- Dizziness
- Tiredness
- Sleepiness
- Rashes
Precautions and Warnings
Alcohol
UNSAFEYou should not consume alcohol while on treatment with Naxdom Tablet, as the chances of stomach ulceration and bleeding increase. Thus, you should avoid consuming alcohol while on treatment with this medicine.
Pregnancy
WITH CAUTIONNaxdom Tablet should be avoided during pregnancy.
Breastfeeding
WITH CAUTIONNaxdom Tablet passes into human milk. Thus, either medicine or breastfeeding should be discontinued.
Driving
WITH CAUTIONNaxdom Tablet may cause dizziness, drowsiness, fatigue, and vision problems. Therefore, you should avoid driving if you do not feel well or are unable to be alert.
Other General Warnings
- You have any stomach and intestinal diseases.
- You smoke or consume alcohol regularly.
- You are above 65 years of age.
- You had or have problems with your heart, liver, or kidney.
- You have diabetes or high blood pressure or high cholesterol.
- You have asthma or any problems with your breathing.
- You are planning to have a baby, as Naproxen may interfere with female fertility.
- You are using other medicines that may cause bleeding and ulcers in the stomach.
- You have to undergo any blood or urine tests.
- You are taking medicines or painkillers for headaches too often.
- You are above 12 years of age with a body weight below 35 kgs.
- You are taking apomorphine.
- You have developed an allergy or skin rash after taking this medicine.
- You have an autoimmune disorder called systemic lupus erythematosus or any tissue disorder or any blood clotting issues.
- You have Parkinson’s disease, asthma, colitis, or Crohn's disease.
Doctor’s suggestion
Directions for use
- Naxdom Tablet should be taken as directed by your doctor.
- Swallow it whole with a glass of water.
- Do not cut, break or chew the medicine.
- It would be best if you took it at a fixed time for optimal results.
- Do not consume more than the dose prescribed by your doctor.
Storage and disposal
- Store Naxdom Tablet below 25°C protected from moisture, sunlight, and heat.
- Keep this medicine away from children and pets.
Dosage
Overdose
Missed a dose
How Naxdom works
- Naxdom Tablet contains a combination of naproxen and domperidone as active substances.
- Naproxen belongs to a group of medicine that blocks the effect of inflammatory chemicals. So, the symptoms like redness, pain, inflammation, and swelling improve gradually.
- Domperidone is used to control nausea and vomiting. It prevents food from coming back up in the oesophagus (food pipe), which may occur due to stomach irritation caused by naproxen and other painkillers and in migraine attacks.
Interactions
Drug interactions of Naxdom with other medicine salt
Food interactions
Frequently asked questions
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References
- Motilium Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 21 December 2021]
- Naproxen Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 21 December 2021]
- Motilium Film-coated Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 21 December 2021]
- Drugs.com. Domperidone: Uses, Dosage, Side Effects, Warnings. Drugs.com. 2024 [cited 24 December 2024]
- Drugs.com. Naproxen: Uses, Dosage, Side Effects, Warnings [Internet]. Drugs.com; 2024 [cited 24 December 2024]
- U.S. Food and Drug Administration. Naproxen; 2026 [cited 22 May 2026]
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