Betnovate-N Cream
25g Cream in Tube
Product Summary
Betnovate N Cream, from Glaxosmithkline, combines betamethasone 0.1% w/w and neomycin 0.5% w/w as a topical steroid and antibiotic for steroid-responsive inflammatory skin conditions with secondary bacterial infection. Betamethasone reduces skin inflammation, while neomycin stops susceptible bacteria from growing on affected skin.
Medically Reviewed by Dr. Jagriti Jha
Last updated on: 13 October 2026 | 7:06 PM (IST)
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GLAXOSMITHKLINE
Dose Form
CREAM
Expiry
General Information
| Therapy | Topical antibiotic and steroid |
| Composition | Betamethasone(0.1 %W/W)+Neomycin(0.5 %W/W) Betamethasone 0.1 %W/W+Neomycin 0.5 %W/W |
Betamethasone 0.1 %W/W+Neomycin 0.5 %W/W
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*Offer applicable on orders above ₹1000About Betnovate
Betnovate-N Cream is a medication used to treat various skin conditions, including redness, inflammation, itching, and rashes. It is often prescribed for conditions like dermatitis, psoriasis, and eczema. These conditions can cause the skin to become dry, flaky, or swollen, and Betnovate-N helps provide relief from these uncomfortable symptoms.
This cream contains two main ingredients: betamethasone and neomycin. Betamethasone is a steroid that helps reduce inflammation, swelling, and redness in the skin. Neomycin is an antibiotic that works by fighting bacterial infections on the skin. Together, these ingredients help soothe irritated skin while preventing or treating infection.
Betnovate-N Cream should be used exactly as directed by your doctor or pharmacist. It is for external use only. Apply a thin layer to clean, dry skin and gently massage it in until fully absorbed. Use just enough cream to cover the affected area. Always wash your hands before and after applying the cream, unless you are treating a specific area of your hands.
While using Betnovate-N Cream, protect the treated skin from direct sunlight. Try to avoid applying other skin products in the same area unless your doctor has specifically instructed you to do so. Do not cover the treated skin with tight bandages or dressings unless directed to do so.
Other creams, such as Dipnate N contain the same active ingredients and may be used to treat similar skin problems. However, you should only use the product prescribed specifically for you. If your symptoms do not improve or if you experience any irritation or an unusual reaction, consult your doctor for further advice.
Uses
- Prickly heat (Miliaria) is associated with significant inflammation or secondary bacterial infection.
- Redness, itching, and swelling following insect bites (Insect bite reactions)
- Inflammation of the outer ear canal, commonly known as swimmer's ear (Otitis externa)
- Skin inflammation caused by irritants or allergens (Irritant or allergic contact dermatitis)
- Scaly, flaky skin, usually affecting the scalp or face (Seborrhoeic dermatitis)
- Inflammation of skin folds around the anal or genital area (Anal and genital intertrigo)
- Coin-shaped itchy skin patches (Nummular eczema)
- Itchy, inflamed skin (Atopic dermatitis)
- Thickened, itchy skin (Lichen simplex)
- Itchy skin nodules (Prurigo nodularis)
- Itchy, flat-topped skin rash (Lichen planus)
- Red, scaly skin patches (Psoriasis; excluding widespread plaque psoriasis)
Contraindications
- Known hypersensitivity to betamethasone valerate, neomycin sulphate, or any component of the cream
- children under 2 years of age.
- Rosacea (facial redness and visible blood vessels)
- Acne vulgaris (acne)
- Perioral dermatitis (rash around the mouth)
- Itching without inflammation
- Perianal or genital itching
- Viral skin infections
- Primary bacterial skin infections that do not require topical corticosteroid therapy.
- Secondary infections caused by Pseudomonas/Proteus species
- Otitis externa with a perforated eardrum, due to the risk of ear toxicity
- Avoid using this cream in large amounts or for a long time unless advised by your doctor, as excessive absorption may increase the risk of kidney- or hearing-related side effects.
Side effects
- Burning, pain, or irritation at the application site
- Itching
- Dry skin
- Rash
- Allergic contact dermatitis
- Erythema (redness of skin)
- Skin thinning (atrophy)
- Skin striae
- Hypopigmentation
- Hypertrichosis - increased hair growth
- Changes in skin colour
- Cataract
- Glaucoma
- Blurred vision
- Delayed wound healing
Precautions and Warnings
Alcohol
SAFENo specific interaction between this cream and alcohol has been reported.
Pregnancy
WITH CAUTIONThis cream should be used during pregnancy only if prescribed by a doctor.
Breastfeeding
WITH CAUTIONConsult your doctor before using this cream while breastfeeding. Avoid applying it to the breast before feeding.
Driving
SAFEThis cream is not expected to affect the ability to drive or operate machinery.
Other General Warnings
- You are experiencing skin thinning or damage after applying the Betnovate-N cream.
- Avoid prolonged use, especially on the face, as it may increase the risk of local side effects.
- Avoid contact with the eyes. Repeated exposure may increase the risk of visual disturbances, cataracts, or glaucoma.
- Use caution when applying the cream to large areas of the body, under airtight dressings, nappies (diapers), as this may increase absorption of the corticosteroid. And rarely leads to Cushing’s syndrome.
- Prolonged use of neomycin may result in the overgrowth of resistant organisms.
- If irritation, sensitisation, or an allergic reaction occurs, stop using and consult your doctor.
- Use in children (above 2 years) should be limited to the shortest duration necessary and under medical supervision.
- Do not use this cream for longer than prescribed by your doctor.
- Use with caution in psoriasis because relapse, tolerance, generalized pustular psoriasis, and systemic toxicity may occur.
- Do not smoke or go near naked flames after applying this medication, as it may catch fire easily due to paraffin. apply it to the face where the skin becomes thin unless a doctor advises otherwise.
Directions for use
- Always use this cream according to your doctor's instructions:
- Clean and dry the affected area before application.
- Apply a thin layer of the cream to the affected skin.
- Gently rub it into the skin until absorbed.
- Wash your hands after application unless your hands are the area affected.
- Use only for the duration recommended by your doctor.
Storage and disposal
- Store below 25°C.
- Keep the tube closed when not in use.
- Do not freeze or dilute.
- Keep out of reach of children.
- Store away from stoves, lighters, or other similar substances that can cause fire.
- Do not use after the expiry date.
- Dispose of unused cream according to local regulations or your doctor's advice.
Quick tips
- Apply only to the affected area as directed by your doctor.
- Avoid contact with the eyes, mouth, and other mucous membranes.
- Do not cover the area where the cream is applied with bandages or dressings unless advised by your doctor.
- Use for seven days and then consult your doctor for switching to another cream not containing neomycin. Do not use the cream for longer than prescribed.
- If the skin infection worsens or fails to improve, discontinue treatment and consult your doctor.
- Stop using the cream and seek medical advice if you develop signs of an allergic reaction.
Dosage
Overdose
- Use this cream exactly as prescribed by your doctor. The amount and duration of use will depend on the condition being addressed and your response to therapy.
- Excessive or prolonged use may increase the risk of systemic corticosteroid effects and other adverse reactions. In case of accidental ingestion or excessive use, seek medical advice.
Missed a dose
How Betnovate works
- The main ingredients in this medication work together to help control inflammation and address associated bacterial infection. They do so by:
- Betamethasone valerate reduces inflammation, redness, swelling, and itching associated with skin conditions.
- Neomycin sulphate works to prevent the growth of susceptible bacteria that may cause or worsen skin infections.
Interactions
Drug interactions of Betnovate with other medicine salt
Food interactions
Frequently asked questions
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References
- Betnovate Cream - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 09th Oct 2025]
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 09th Oct 2025]
- MedlinePlus. Betamethasone topical. [Internet]. Bethesda (MD): National Library of Medicine (US); 2025 [cited 09th Oct 2025]
- GlaxoSmithKline. Betnovate-N: Betamethasone Valerate and Neomycin Skin Cream [Internet]. GlaxoSmithKline; 2025 [cited 09th Oct 2025]
- DrugBank. Neomycin [Internet]. DrugBank; 2025 [cited 09th Oct 2025]
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