Acemiz -MR Tablet
10 Tablet(s) in Strip
Product Summary
Acemiz MR Tablet is a pain-relieving, anti-inflammatory and muscle-relaxant combination used to treat painful muscle spasms and pain with inflammation in musculoskeletal conditions. It contains aceclofenac 100 mg, paracetamol 325 mg and chlorzoxazone 250 mg. Manufactured by Lupin, the ingredients reduce pain-related chemicals and relax skeletal muscles.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 12:06 PM (IST)
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General Information
| Therapy | Muscle relaxant, analgesic/antipyretic |
| Composition | Aceclofenac(100.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg)+Chlorzoxazone(250.0 Mg) Aceclofenac 100.0 Mg+Paracetamol / Acetaminophen 325.0 Mg+Chlorzoxazone 250.0 Mg |
Aceclofenac 100.0 Mg+Paracetamol / Acetaminophen 325.0 Mg+Chlorzoxazone 250.0 Mg
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*Offer applicable on orders above ₹1000About Acemiz
Acemiz MR tablets are a combination medication used to relieve pain and inflammation associated with various conditions, including muscle spasms, musculoskeletal disorders, and post-operative pain. They contain a combination of aceclofenac, paracetamol, and chlorzoxazone, which work together to reduce inflammation, relax muscles, and block pain signals.
Aceclofenac, paracetamol, and chlorzoxazone are also present in Movexx MR tablet, Dolokind MR tablet, Dolowin MR tablet, Aceflam MR tablet, and Akilos MR tablet.
This tablet should be taken as directed by the doctor and in doses and duration as prescribed. You can take this with or without food. But it will be better if you take it with meals to avoid stomach upset. Before starting the treatment with Acemiz MR, inform your doctor about your past medical and medicinal history.
Uses
Contraindications
- If you are allergic to aceclofenac, paracetamol, chlorzoxazone or any ingredients of Acemiz MR tablet.
- If you are experiencing bleeding from the stomach and intestine or have an active peptic ulcer.
- If you are allergic to other painkillers such as aspirin and have experienced severe asthma, rashes or any other allergy.
- If you are suffering from any heart disease like heart failure and high blood pressure.
- If you have problems with kidney and liver function.
- If you are pregnant or elderly (65 years of age or older).
Side effects
- Dizziness
- Lightheadedness
- Nausea
- Vomiting
- Weakness
- Fatigue
- Liver problem
Precautions and Warnings
Alcohol
It is advised to avoid the consumption of alcohol during the treatment with Acemiz MR tablet as it may worsen your liver problems and other side effects.
Pregnancy
It is unsafe to take Acemiz MR tablets during pregnancy. Hence, it should not be taken by pregnant women. Taking this medicine during pregnancy can cause defects in the baby's heart or even delay of delivery or increase the risk of bleeding.
Breastfeeding
It is advised not to use Acemiz MR tablet if you are breastfeeding as it may cause harm to your newborn baby.
Driving
It is advised not to drive or use machines when you have taken Acemiz MR tablet as it may cause dizziness.
Other General Warnings
- You have kidney or liver problems.
- You have heart problems like high blood pressure, heart failure, etc.
- If you are an elderly patient taking diuretics or have a kidney disorder, this medicine can increase the risk of kidney failure.
- You are suffering from gastrointestinal problems like bleeding, ulcers in the intestine (perforation) or Crohn's disease, or you are passing black tarry stools.
- You have asthma, and this medicine can worsen the same.
- You have systemic lupus erythematosus (an autoimmune disorder).
- If you are an alcoholic, then concomitant use of this medicine can damage the liver.
- You have disorders related to blood, like clotting problems and anaemia.
- You have skin rashes & lesions after taking this medicine.
Directions for use
- Acemiz MR tablet has to be taken as advised by the doctor with a sufficient amount of water. It is taken as directed by your doctor and preferably after meals.
Storage and disposal
- Acemiz MR tablet should be store below 30°C, in a cool dry place. Protect it from moisture and heat.
- Keep it away from the children and pets.
- Discard the unused and expired medicines appropriately. Do not flush or throw the tablet in the sink.
Quick tips
- Acemiz MR tablet is a pain-reducing medicine used to treat painful muscle cramps associated with musculoskeletal conditions. It also reduces joint swelling and inflammation. Do not take this medicine for any condition other than that prescribed by your doctor.
- Take it at the exact recommended dose. Do not exceed the stated dose. Taking more than the daily dose may cause serious liver problems or allergic reactions.
- Acemiz MR tablet is not recommended for use in children less than 10 years of age.
- Inform your doctor if you are pregnant, planning on becoming pregnant or breastfeeding before taking this medicine. Also, inform about your medical history, especially if you have heart or blood vessel-related disorders or gastrointestinal bleeding.
- Do not take any other paracetamol-containing products while taking the Acemiz MR tablet.
- Dizziness, fatigue, weakness, and nausea/vomiting may occur in some individuals when this medicine is used. Inform your doctor if these effects bother you or do not go away.
- Tell your doctor if you have a history or have an alcohol addiction.
Dosage
Overdose
Missed a dose
How Acemiz works
- Acemiz MR tablet works by the combined action of its three components. Aceclofenac and paracetamol inhibit the synthesis of prostaglandins, which are responsible for causing pain, swelling and inflammation, thus offering anti-inflammatory properties.
- Chlorzoxazone is a muscle relaxant that works by blocking the signals of painful sensation from the nerve to the brain, reducing pain and stiffness.
Interactions
Drug interactions of Acemiz with other medicine salt
Food interactions
- Take the tablet with food to reduce the risk of stomach irritation.
- Avoid alcohol, as it can increase the risk of liver damage due to paracetamol and may worsen drowsiness caused by chlorzoxazone.
- Limit caffeine-containing drinks (such as tea, coffee, and cola) because they can contribute to nervousness or restlessness.
- Avoid high-fat, spicy, or oily meals, as they can worsen stomach discomfort.
- Drink plenty of water and eat light, balanced meals to support digestion and reduce gastric upset.
Frequently asked questions
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References
- DailyMed - CHLORZOXAZONE tablet [Internet]. Dailymed.nlm.nih.gov. 2021 [cited 01 Sep 2025]
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 2733, Chlorzoxazone. Retrieved Sep 01, 2025
- ScienceDirect. Aceclofenac. ScienceDirect. [cited 01 Sep 2025].
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 1983, Acetaminophen. Retrieved Sep 01, 2025
- ScienceDirect. Paracetamol. ScienceDirect. [cited 01 Sep 2025].
- Kumar S, Rani S, Siwach R, Verma P. Efficacy and safety of fixed dose combination of thiocolchicoside and aceclofenac versus chlorzoxazone, aceclofenac, and paracetamol in acute lower backache with muscle spasm. Int J Appl Basic Med Res. 2014 Jul. [cited 01 Sep 2025].
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