Anti Nuclear Antibody (ANA-Elisa) Test in Gurgaon - Price & Details

The antinuclear antibody (ANA-Elisa) test is a blood test that detects antinuclear antibodies, which may be associated with several autoimmune conditions. Normally, the immune system protects the body from infections and other harmful substances while distinguishing them from healthy cells and tissues. In autoimmune conditions, this protective system can become misdirected and mistakenly attack the body’s own cells and tissues. Autoimmune conditions can affect different organs and may cause varied symptoms. For example, rheumatoid arthritis and lupus can cause joint pain and stiffness, while lupus may also cause skin rashes and increased sensitivity to sunlight. Dry eyes and mouth may occur with Sjögren syndrome, whereas systemic sclerosis can cause skin thickening or tightening. Doctors may recommend an ANA-Elisa test when symptoms such as persistent or unexplained joint or muscle pain, fatigue, fever, skin changes, or swelling suggest a possible autoimmune condition. It may also be considered when unexplained problems affecting an organ are present. ANA results are assessed along with your medical history, symptoms, and other investigations, such as complete blood count, urinalysis, kidney or liver function tests, and specific antibody tests. A positive ANA result alone does not confirm a particular autoimmune disease.

The ANA-Elisa test may be recommended when your symptoms do not have another clear explanation or when your medical history and examination suggest a possible autoimmune condition. Your doctor may recommend this test when there are signs or symptoms such as:

• Persistent or unexplained fatigue
• Joint pain, stiffness, or swelling
• Muscle pain or weakness
• Recurrent fever
• Unexplained skin rashes, blisters, or changes in skin colour
• Swelling of the salivary glands, with dry mouth or dry eyes
• Symptoms affecting multiple parts of the body
• Unexplained abdominal pain
• Unexplained hair loss
• Increased sensitivity to sunlight
• Fingers or toes that turn unusually pale, blue, or red, especially in cold weather

Note: ANA testing is not usually recommended as a routine screening test for people without symptoms suggestive of an autoimmune disorder. This is because antinuclear antibodies can also be found in some healthy people, so a positive result does not necessarily mean that you have an autoimmune disease.

The ANA-Elisa test can help doctors evaluate certain autoimmune and connective tissue diseases. ANA is commonly associated with conditions such as:

• Systemic lupus erythematosus (SLE): A long-term autoimmune disease that can affect several parts of the body, including the joints, skin, kidneys, heart, lungs, blood vessels, and nervous system.
• Sjögren syndrome: An autoimmune condition that commonly affects the glands that produce tears and saliva, causing dry eyes and dry mouth.
• Scleroderma (systemic sclerosis): An autoimmune condition that can cause changes in the skin and may affect blood vessels and internal organs.
• Inflammatory muscle diseases (myositis): A group of conditions that can cause inflammation and weakness of the muscles.
• Rheumatoid arthritis: An autoimmune condition that mainly affects the joints, causing pain, stiffness, and swelling.
• Psoriatic arthritis: An inflammatory condition that can cause joint pain, stiffness, and swelling in people with psoriasis.
• Autoimmune hepatitis: A condition in which the immune system attacks the liver, causing inflammation.
• Autoimmune thyroid diseases: Conditions in which the immune system attacks the thyroid gland and may affect thyroid hormone production.

Note: ANA is not specific to any one disease and cannot diagnose these conditions on its own. A positive ANA result may also occur in some healthy people and in certain other conditions. Doctors interpret the result along with your symptoms, medical history, examination, and other test results.

What to Expect Before the ANA-Elisa Test?

• There are no special preparations required for this test. You may eat and drink normally. Sample collection can be scheduled any time of day.
• The ANA-Elisa test results may be affected by medications, supplements, and certain health conditions, such as viral or bacterial illnesses. Inform your doctor about these before undergoing the test.

What to Expect During the Blood Collection?

• A trained phlebotomist will arrive at your home at the scheduled time.
• A small blood sample will be collected from a vein in your arm using a sterile needle after the skin is cleaned with an antiseptic. You may feel a slight pricking sensation.
• The procedure usually takes only a few minutes.

What to Expect After the ANA-Elisa Test?

• Mild throbbing may be felt at the blood draw site for a few minutes after the blood is drawn.
• Occasionally, you may feel dizzy, in which case you may lie down for a while until the feeling passes.
• The blood sample is taken to the laboratory for analysis, and results are usually made available within a few hours, and they can be downloaded from the PharmEasy platform.
• Depending on the findings, additional investigations may be recommended for further evaluation.

Note: If you notice anything unusual at the puncture site, such as persistent bleeding, a rash, or pain, consult your healthcare provider.

The ANA-Elisa test measures antinuclear antibodies (ANA) in your blood using the enzyme-linked immunosorbent assay (ELISA) method. The result is reported as an OD (optical density) ratio.

The reference range and cut-off values may vary depending on the laboratory and the testing method used. Your ANA-Elisa report will include the applicable reference range for interpreting your result.

A positive ANA result is not specific to any one condition. ANA may also be found in some healthy individuals, particularly older adults, as well as in certain infections, malignancies, and drug-induced autoimmune conditions. The final diagnosis is made by a doctor based on the overall clinical picture, and other relevant investigations.

Potential Risks and Complications

• The ANA-Elisa test is a routine blood test and is considered safe with minimal risk. Some individuals may experience mild discomfort, minor bruising, or slight bleeding at the site where blood is drawn. Occasional dizziness or light-headedness may also occur in some cases.
• In rare instances, there may be difficulty in locating a suitable vein, or a very small possibility of infection at the puncture site.

Understanding ANA-Elisa Test Limitations

• ANA can sometimes be detected in healthy people at low levels, so a positive result does not always mean that an autoimmune disease is present.
• Even though this test has high sensitivity for conditions such as lupus and systemic sclerosis, it has low specificity for actually confirming an autoimmune disease.
• A weak positive result is more likely to be a false-positive, while a stronger positive is more likely to reflect an actual underlying condition.
• A positive result usually needs follow-up testing with specific antibody tests as the ANA-Elisa test cannot determine which autoimmune condition is present.
• A negative result does not fully exclude certain autoimmune conditions, as some of them do not produce ANA. Also, if it is tested in the very early stages of the condition, ANA might not have risen to detectable levels yet.

The ANA-Elisa test is priced at around ₹449, though the exact cost can vary based on your location in Gurgaon and available offers. To better understand the pricing differences, you can compare the ANA-Elisa test costs across major cities in India.

You can book the Anti Nuclear Antibody (ANA-Elisa)Test in Gurgaon through PharmEasy with convenient home sample collection across several localities, including:

• DLF Phase 1
• DLF Phase 2
• DLF Phase 3
• DLF Phase 4
• DLF Phase 5
• Udyog Vihar
• Sector 23
• Sector 44
• Sector 67
• Sector 70
• Sushant Lok
• Sector 5
• Palam Vihar
• Nirvana Country
• Sector 14
• Sector 31
• Sector 46
• Sector 49
• Sector 56
• Sector 57

You can also check service availability during purchase by entering your PIN code.