Chlorpheniramine Maleate+Dextromethorphan

Molecule Description

Chlorpheniramine maleate+Dextromethorphan hydrobromide is a combination medicine...
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Uses of Chlorpheniramine Maleate+Dextromethorphan

Chlorpheniramine maleate+Dextromethorphan hydrobromide is used to provide temporary relief from sneezing, cough or runny nose due to minor throat and airway irritation which occurs during common cold ...
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Contraindications of Chlorpheniramine Maleate+Dextromethorphan

When should one not use Chlorpheniramine Maleate+Dextromethorphan

If you are allergic to chlorpheniramine maleate, dextromethorphan hydrobromide or similar medicines. If you are taking medications like sodium oxybate, which is used in preventing daytime sleepiness....
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Side effects of Chlorpheniramine Maleate+Dextromethorphan

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Drowsiness
  • Nausea
  • Vomiting
  • Upset stomach
  • Tiredness

Precautions and Warnings of Chlorpheniramine Maleate+Dextromethorphan



Can I take chlorpheniramine maleate+dextromethorphan hydrobromide during pregnancy?
Chlorpheniramine maleate+Dextromethorphan hydrobromide should only be used during pregnancy if prescribed by the doctor as there is limited safety information available.

Breast Feeding

Can I take chlorpheniramine maleate+dextromethorphan hydrobromide while breastfeeding?
Chlorpheniramine maleate+Dextromethorphan hydrobromide should only be used while breastfeeding if prescribed by the doctor as there is limited safety information available.


Can I drive if I have consumed chlorpheniramine maleate+dextromethorphan hydrobromide?
Chlorpheniramine maleate+Dextromethorphan hydrobromide may make you feel dizzy & drowsy, thus you need to be cautious while driving.


Can I consume alcohol with chlorpheniramine maleate+dextromethorphan hydrobromide?
Avoid consuming alcohol with chlorpheniramine maleate+dextromethorphan hydrobromide, as it may worsen the side effects.

Other General Warnings

Talk to your doctor if
  • You have problems with your heart, liver or kidneys.
  • You have any breathing problems, high blood pressure or fits.
  • You have glaucoma (increased pressure in the eye).
  • You have difficulty in passing urine or frequent urge to urinate (enlarged prostate).
  • You have a cough.
  • Your cough lasts for more than 7 days or is accompanied by fever, rash or persistent headache.
  • It is not recommended for use in children below 2 years of age.

Mode of Action of Chlorpheniramine Maleate+Dextromethorphan

How Does It Work?

  • Natural substances like histamine released in our body are responsible for allergies such as sneezing or runny nose. Chlorpheniramine works by blocking the effect of these substances and provides reli...
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  • There are specific areas in the brain (cough centre), which when activated produces coughing. Dextromethorphan affects these areas and deactivates them, thus helping in relieving the coughing.

Interactions of Chlorpheniramine Maleate+Dextromethorphan

Interactions with other medicines

  • Some medicines can affect the way chlorpheniramine maleate+dextromethorphan hydrobromide works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking medicines to treat your psychiatric illnesses, cough, allergy or are taking medicines like anti-histaminic medicines, muscle-relaxants.
  • Chlorpheniramine Maleate+Dextromethorphan Hydrobromide should not be taken along with medicines called monoamine oxidase inhibitors (MAOIs) which are used in the treatment of depression, Parkinson’s d...
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Dosage of Chlorpheniramine Maleate+Dextromethorphan


Symptoms of overdose may include drowsiness, dizziness, confusion, hallucination, nervousness, difficulty in passing urine, fits, fast or irregular heartbeats. Seek urgent medical help if you suspect ...
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Missed a Dose

If you have missed any dose of chlorpheniramine maleate+dextromethorphan hydrobromide, then take it as soon as you remember. If it is already time for the next dose, then skip the missed dose and foll...
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Content Details


Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Is Chlorpheniramine maleate+Dextromethorphan hydrobromide safe to use in children?

A: Chlorpheniramine maleate+Dextromethorphan hydrobromide should not be used in children below 2 years old. Do not give any medication to your child without consulting a child specialist.

Q: In which all dosage forms is Chlorpheniramine maleate+Dextromethorphan hydrobromide available?

A: Chlorpheniramine maleate+Dextromethorphan hydrobromide is available in the form of tablet, syrup, suspension, oral drops.
Last Updated on: 26 Oct 2021 | 10:06 PM (IST)
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