Syndopa Plus Tablet
15 Tablet(s) in StripProduct Summary
Syndopa Plus Tablet is a dopamine-replacement and antiparkinson combination from Sun Pharma containing carbidopa 25 mg and levodopa 100 mg, used to treat Parkinson's disease symptoms such as tremor and muscle stiffness. Levodopa is converted into dopamine in the brain, while carbidopa reduces its breakdown before it reaches the brain.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 3:32 PM (IST)
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SUN PHARMA
Dose Form
TABLET
Expiry
General Information
| Therapy | Anti-parkinsonian |
| Composition | Carbidopa(25.0 Mg)+Levodopa(100.0 Mg) Carbidopa 25.0 Mg+Levodopa 100.0 Mg |
Carbidopa 25.0 Mg+Levodopa 100.0 Mg

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*Offer applicable on orders above ₹1000About Syndopa
Syndopa Plus Tablet is a medication primarily used in the treatment of Parkinson’s disease, a central nervous system disorder that affects movement and coordination. The disease is characterized by symptoms such as tremors, spasms, muscle stiffness, difficulty in walking, and poor balance. These symptoms occur due to low dopamine levels in the brain, as the neurons that produce dopamine gradually die.
Syndopa Plus Tablet contains two active ingredients: Levodopa and Carbidopa. Levodopa, a central nervous system agent, is converted into dopamine in the brain, which helps improve movement and control. Carbidopa, a decarboxylase inhibitor, prevents the breakdown of Levodopa in the bloodstream, ensuring that more Levodopa reaches the brain and remains effective.
This medication should be taken exactly as prescribed by your doctor, and its use should continue as directed. Common side effects include nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (involuntary muscle movements). These side effects usually resolve over time and do not require medical attention unless they persist or worsen. If you experience severe or persistent side effects, consult your doctor promptly.
It is important to inform your doctor if you are allergic to any components of the medication or have a medical history that includes glaucoma, asthma, dizziness, mental illness, or intense urges such as gambling, overeating, or increased sexual impulses. Additionally, Syndopa Plus should not be taken during pregnancy or breastfeeding without medical advice. Levodopa must also be discontinued at least 12 hours before starting this medication. Always communicate openly with your doctor about your medical condition and any concerns before beginning Syndopa Plus Tablet.
Syndopa CR tablet, Tidomet Plus tablet and LCD tablet are a few other medicines containing levodopa and carbidopa.
Uses
Contraindications
- If you are allergic to levodopa, carbidopa or any ingredients of Syndopa Plus tablet.
- If you have a history of skin cancer called melanoma or the presence of moles on the skin, which a doctor has not clinically checked.
- If you are taking medicines for psychiatric health disorders belonging to a class, MOAIs like Rasagiline should be stopped at least 14 days before you start taking this medicine.
- If you have raised pressure in the eyes, it is a condition called narrow-angle Glaucoma.
- If you are diagnosed with any serious psychiatric illness.
- If you are pregnant or planning to get pregnant, or if you are a breastfeeding mother.
Side effects
- Uncontrolled movements
- Headache
- Nausea
- Vomiting
- Dry mouth
- Diarrhoea
- Reduced appetite
- Drowsiness
Precautions and Warnings
Alcohol
UNSAFEYou should avoid alcohol consumption while taking Syndopa Plus tablet.
Pregnancy
WITH CAUTIONInsufficient data is available regarding Syndopa Plus Tablet's possible side effects on the foetus. Thus, pregnant women or women who are planning to get pregnant must take this medicine on doctor's prescription only.
Breastfeeding
UNSAFEIt is not advised to take Syndopa Plus tablet if you are breastfeeding your baby as levodopa passes into breast milk.
Driving
UNSAFEIt is not advised to drive or operate heavy machinery if you have taken Syndopa Plus tablet as it makes you dizzy and drowsy and can also affect your balance and movements.
Other General Warnings
- You experience mood changes, sleep attacks or excessive sleepiness.
- You have a history of fits.
- You have or had an ulcer in your stomach or intestine.
- You have had a heart attack, heart disorder, or breathing problems.
- You have had kidney, liver or hormonal problems.
- You have a due surgery or operation.
- If you have an eye condition called 'glaucoma’, you will need to have regular checks on the pressure in your eye.
Directions for use
- Take Syndopa Plus tablet as a whole with a sufficient amount of water.
- Try to take it at a fixed time every day as advised by your doctor.
- Do not skip the doses even if you feel better.
Storage and disposal
- Store Syndopa Plus tablet at a temperature below 30°C.
- Keep it out of the reach of children and pets.
Quick tips
- Follow your doctor's prescribed dose and duration, and do not take a double dose if you miss one.
- Lifestyle changes such as daily exercise (20-30 minutes), avoiding smoking, and limiting alcohol are also recommended.
- Inform your doctor if you're pregnant, planning to become pregnant, or breastfeeding. If you become pregnant while using this medication, stop immediately and consult your doctor.
- Report any side effects like dry mouth, headache, reduced appetite, diarrhea, uncontrolled movements, or nausea/vomiting.
Dosage
Overdose
Missed a dose
How Syndopa works
Interactions
Interactions with other medicines
- Some medicines can affect the way the Syndopa Plus tablet works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking any other medicine especially to treat Parkinson’s disease.
- If you are taking any iron preparations, it may decrease the effectiveness of the Syndopa Plus tablet when used concomitantly.
- Medicine for any psychiatric illness may cause worsening of side effects; the dose needs to be adjusted.
- The patient’s response should be monitored when taking Syndopa Plus tablet with anticholinergic preparations like Benzatropine and Procyclidine.
- You may experience low blood pressure on standing suddenly from lying posture if you are on any antihypertensives.
- Medicine for tuberculosis and epilepsy may require a change in dosage.
Food interactions
Frequently asked questions
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References
- CDSCO. Levodopa/Carbidopa [Internet]. Cdscoonline.gov.in. 2022 [cited 13 May 2022]
- Lactmed - Levodopa [Internet]. Ncbi.nlm.nih.gov. 2022 [cited 13 May 2022]
- DrugBank Online. Carbidopa [Internet]. DrugBank; 2024 [cited 26 December 2024]
- MedlinePlus. Levodopa and Carbidopa: MedlinePlus Drug Information [Internet]. National Library of Medicine (US); 2024 [cited 26 December 2024]
- ScienceDirect. Carbidopa. [Internet]. 2024 [cited 26 December 2024]
- PubChem. Carbidopa [Internet]. National Library of Medicine (US), National Center for Biotechnology Information; 2024 [cited 26 December 2024]
- Sinemet Plus 25 mg/100 mg Tablets (co-careldopa) - Summary of Product Characteristics (SmPC) (emc). Accessed 31 Jul 2026.
- Sinemet Plus 25 mg/100 mg Tablets - Patient Information Leaflet (PIL) (emc). Accessed 31 Jul 2026.
- Co-Careldopa 25 mg/100 mg tablets - Summary of Product Characteristics (SmPC) (emc). Accessed 31 Jul 2026.
- Sinemet 12.5 mg/50 mg Tablets - Summary of Product Characteristics (SmPC) (emc). Accessed 31 Jul 2026.
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