CBD oil is a non-intoxicating compound found in cannabis plants.
It’s known for its benefits in managing various types of pain, including neuropathic, arthritis, chronic, and inflammation-associated pain.
Some scientific studies on animals suggest that it may help reduce pain and inflammation.
It’s crucial to consult your doctor before supplementing your pain management plan with CBD oil.
Introduction
Lately, CBD oil has been in the limelight as a potential natural answer to various health concerns. These include many forms of pain relief. Extracted from the cannabis plant, CBD oil is praised for its possible healing effects without the mind-altering impacts often linked to marijuana.
In this in-depth blog post, we will dig deep into the realm of CBD oil and its possible effectiveness in managing different types of pain. We will uncover the science behind CBD oil, and how it’s obtained from the cannabis plant So, fasten your seat belt and prepare to discover all there is to know about the potential pros and cons of using CBD oil for managing pain.
Did you know?
CBD oil is derived from hemp and does not cause a “high” like marijuana.Source: cdc.gov
CBD oil may have potential side effects, including liver damage and interference with other drugs. Source: cdc.gov
CBD has a calming effect on the central nervous system. source: PMC
Understanding CBD Oil
To completely realise the possible benefits of CBD oil for pain relief, it’s crucial first to get what CBD oil is. We also need to understand how it stands out from other parts of the cannabis plant.
What is CBD oil?
Cannabidiol (CBD) oil is a chemical compound. . It’s taken out of cannabis plants like hemp or marijuana. CBD is one of over 100 known cannabinoids found in the cannabis plant. It’s the key non-intoxicating element. This means that unlike THC, its mind-altering sibling, CBD does not give you a “high” or intoxicating effect.
Difference between CBD and THC
The main difference between CBD and THC is their mind-altering traits. While THC gives the “high” linked with marijuana use, CBD is non-mind-altering. This means it doesn’t affect your thinking abilities or produce any kind of intoxication.
Full-spectrum, broad-spectrum, and CBD isolate explained
When looking for CBD oil, you might find terms like full-spectrum, broad-spectrum, and CBD isolate. Here is a quick overview of each type:
Full-spectrum CBD oil holds all the naturally occurring compounds found in the cannabis plant. These include THC (in a small amount – less than 0.3%), other cannabinoids, terpenes, and flavonoids. This combination is believed to create an “entourage effect.” This enhances CBD’s potential beneficial effects.
Broad-spectrum CBD oil also includes various cannabis compounds but without THC. This type of CBD oil offers some of the entourage effect. This is done without the possible risks tied to THC consumption.
CBD isolate is the purest form of CBD. It contains 99% or more of the compound in isolated form, without any extra cannabinoids, terpenes, or flavonoids. It removes THC and other compounds. This makes it suitable for those who want to avoid any trace of these substances.
How CBD oil is extracted
There are various methods used to extract CBD oil from the cannabis plant. The two most common extraction methods are CO2 extraction and ethanol extraction.
Now, let’s glance at the table below. It shows the pros and cons of the two major extraction methods:
Extraction Method
Pros
Cons
CO2 Extraction
Clean and efficient method Produces high-quality CBD oil
Expensive equipment required More complex process
Ethanol Extraction
Relatively efficient and cost-effective Retains a range of compounds
It may contain chlorophyll and impurities It may require more processing
Be careful with CBD oil since even though it’s often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhoea, reduced appetite, drowsiness and fatigue. CBD can also interact with other medications you’re taking, such as blood thinners.
To see how CBD could help in easing pain, we should understand how it interacts with our body’s endocannabinoid system (ECS).
1. How CBD interacts with the endocannabinoid system (ECS)
The ECS is a complex cell-signaling system. It plays a role in regulating key bodily processes. These include pain sensation, immune response, and mood regulation. It consists of naturally produced cannabinoids called endocannabinoids. It also has receptors called CB1 and CB2.
2. CB1 and CB2 receptors
CB1 receptors are mainly found in the central nervous system. On the other hand, CB2 receptors are more abundant in the immune system and peripheral tissues. Both kinds of receptors play an important role in managing pain by modulating pain perception and related inflammatory responses.
3. Role of endocannabinoids in pain management
Endocannabinoids are signalling molecules. They bind to CB1 and CB2 receptors, thus mediating pain and inflammation signalling pathways. By influencing these receptors, CBD may help the body use its endocannabinoids more effectively. This results in reduced pain perception and inflammation.
Types of pain that may benefit from CBD oil
CBD oil has shown promising results in relieving various types of pain. These include:
1. Neuropathic pain
Neuropathic pain arises from damage or dysfunction of the nervous system. It often results in chronic discomfort. Research suggests that CBD may help alleviate this type of pain. It shows potential benefit by reducing inflammation and blocking pain signals in the nerves.
2. Arthritis pain
Arthritis is characterised by joint inflammation and pain. Some studies indicate that CBD oil may help address arthritis pain. It does this by decreasing inflammation and providing relief from the related discomfort.
3. Chronic pain
Chronic pain refers to persistent, long-term pain that lasts for months or years. While the exact mechanisms by which CBD relieves chronic pain remain unclear, its interaction with the ECS and non-opioid receptors could be responsible for its potential pain-killing effects.
4. Inflammation-associated pain
Inflammation often plays a critical role in the onset and progression of various types of pain. CBD’s anti-inflammatory properties suggest it may be a viable option to address inflammation-related pain.
5. Migraines and headaches
Migraines and headaches are common types of pain that can greatly impair daily functioning. While the evidence is limited, some suggest that CBD may help alleviate migraine symptoms. It does this by reducing inflammation and interacting with neurotransmitters involved in pain sensation.
Scientific Evidence on CBD Oil for Pain Management
While there are many personal accounts claiming that CBD oil can be effective for pain relief, we need strict scientific research to back these claims.
1. Preclinical studies on animal models
Several preclinical studies on animal models have looked into CBD’s effects on inflammatory and neuropathic pain. The results are encouraging.
2. Effects of CBD on inflammatory and neuropathic pain
An extensive review published in the Journal of Experimental Medicine looked at multiple studies. These were analysing the effects of cannabinoids, including CBD, on chronic pain conditions. According to the researchers, there is substantial evidence that cannabinoids could be treated for chronic pain, with CBD showing promise in reducing inflammatory and neuropathic pain specifically.
3. Clinical trials and human studies
Although several clinical trials and human studies have looked at the possible benefits of cannabinoids for pain relief, we need broader research. This is to fully grasp CBD’s efficacy and safety.
4. Cannabinoids for pain relief: A systematic review
A recent systematic review checked the healing effects of cannabinoids in the management of chronic non-cancer pain. The study found moderate-quality evidence backing cannabinoids’ use in treating neuropathic and musculoskeletal pain. However, it stated that high-quality clinical trials are necessary to confirm these findings.
5. Effectiveness of CBD for chronic pain management
A study published in the European Journal of Pain found that CBD could relieve chronic pain caused by various health conditions. These included fibromyalgia, multiple sclerosis, and rheumatoid arthritis. However, more research is needed to confirm the effectiveness of CBD for specific pain types. We also need studies to determine the right dosages.
6. CBD for arthritis: A study on human patients
In a small-scale study on human patients with rheumatoid arthritis, CBD oil was shown to improve pain, sleep quality, and overall life quality. However, these results were self-reported. Larger studies with more comprehensive techniques are needed to validate these findings.
Understanding product labels
Product labels give key information about CBD oil contents. Pay attention to the following details:
CBD content per serving: This will give you an idea of how much CBD is present in each dose of the product.
Recommended serving size: Follow the recommended serving size on the label. This prevents consuming too much or too little. Remember, you can always adjust your dosage based on your unique needs and experience with CBD oil whilst keeping your doctor in the loop.
Are you curious about what to consider when picking up your CBD oil? Let’s look at the overview provided in the table below:
Factor
Considerations
Potency
Match the potency to your pain level and body’s tolerance
Testing
Select a product with independent third-party lab testing for quality and purity
Extraction method
Choose products made using CO2 or ethanol extraction methods for the highest quality CBD oil
Type of CBD
Consider full-spectrum, broad-spectrum, or CBD isolate based on your specific needs and preferences
Flavorings
Opt for flavoured products or those with added ingredients if you dislike the natural taste of CBD oil
Price
Compare prices and choose a product that offers the best value within your budget
How to Use CBD Oil for Pain Relief
Using CBD oil for pain relief can be done in several ways. These include sublingual administration, topical application, ingestion, and inhalation. One should never use CBD oil without a doctor’s advice. The use of CBD oil is also banned in many countries so please the legal guidelines and discuss the same with your doctor.
Application methods that may be advised-
Sublingual administration: Put a few drops of CBD oil under your tongue. Hold it for 30-60 seconds before swallowing. This method allows faster absorption into the bloodstream.
Topical application: Apply CBD oil directly to the skin in the affected area. Softly rub it in for maximum absorption. This is perfect for localised pain and inflammation.
Ingestion: Add CBD oil to food, drinks, or swallow capsules. This offers a handy and secret way to consume CBD oil. Remember, ingesting CBD oil might take longer to give relief as it must first pass through the digestive system.
Inhalation: Vaporizing or smoking CBD oil enables fast absorption into the bloodstream through the lungs. This gives almost instant relief. However, this method may not suit everyone due to possible breathing issues.
Determining the right dosage
Deciding the perfect CBD oil dosage for pain relief depends on several factors. These include body weight, age, metabolism, the severity of pain, and individual sensitivity to CBD. Your doctor will Begin with a small dose and slowly raise it until you feel the desired effects. Consult your healthcare provider for personal advice on CBD dosages and possible interactions with medications or other treatments.
Side Effects and Safety Concerns
Although CBD oil is generally well-tolerated with minimal side effects, it’s key to know of possible safety concerns and drug interactions before using it for pain management.
Potential side effects of CBD oil
Common side effects of CBD oil may include:
Fatigue
Diarrhea
Changes in appetite and weight
Severe side effects and precautions may involve:
Liver damage (especially when using high doses)
Fertility problems in males
Possible higher risk of drug interactions with alcohol and certain medications
Drug interactions
CBD can interact with various medications, potentially causing harmful side effects or reducing their effectiveness. Always consult your healthcare provider before using CBD oil if you’re taking any prescription or over-the-counter medications.
Pros and Cons of Using CBD Oil for Pain Management
Like any treatment, using CBD oil for pain management comes with both benefits and drawbacks. It’s key to weigh the pros and cons before deciding if CBD oil is right for you.
Benefits of using CBD oil for pain
Natural choice rather than pharmaceuticals
Non-addictive and non-psychoactive
Likely anti-inflammatory and pain-killing effects
Limitations and drawbacks
Limited research on human studies
Side effects and potential drug interactions
Differences in quality and effectiveness among products
Does not treat or cure the underlying cause of pain. Only masks the pain and offers symptomatic relief for some time.
Conclusion
CBD oil has popped up as a hopeful natural remedy for pain relief. This may offer potential benefits for those looking for a safer, non-addictive choice to pharmaceutical meds. While current research on the effectiveness of CBD oil for pain management is limited, early findings suggest that it could provide relief from various types of pain. These include neuropathic, arthritis, chronic, and inflammation-associated pain.
When considering using CBD oil for managing pain, weigh the pros and cons, consult with your doctor, pick a high-quality product, and closely monitor your dosage and response. With the right approach, CBD oil may become a valuable addition to your pain management plan.CBD oil use is not legally permitted in many countries, check the legal guidelines of your country before planning to use it.
Frequently Asked Questions (FAQ)
What types of pain can CBD oil potentially help with?
CBD oil might help with various types of pain, including neuropathic, arthritis, chronic, inflammation-associated pain, and migraines.
How do I determine the right dosage for pain management?
Determining the right dosage for pain management depends on factors like body weight, age, metabolism, and severity of pain. Consult your healthcare provider for personal advice on CBD dosages and possible interactions with medications or other treatments.
Is CBD oil safe to use for long-term pain relief?
CBD oil is generally well-tolerated and considered safe for long-term use. However, watch out for potential side effects and consult your healthcare provider if you experience any bad reactions. Also, remember to pick high-quality CBD products and follow the suggested dosages for optimal safety and effectiveness.
What are the possible side effects of using CBD oil for pain?
Some common side effects of CBD oil include fatigue, diarrhoea, and changes in appetite and weight. Severe side effects can include liver damage, fertility problems in males, and potential drug interactions. Consult your healthcare provider before using CBD oil if you’re taking any prescription or over-the-counter meds or supplements.
How do I choose the right CBD oil product for my needs?
Think about factors like potency, third-party testing, extraction method, type of CBD, flavourings, and additives when choosing the right CBD oil product. Read product labels attentively and consult your healthcare provider for personal advice on the best CBD oil to address your pain management needs.
Do healthcare professionals recommend CBD oil for pain management?
While some healthcare workers may suggest CBD oil for managing pain due to its likely benefits if other methods fail., More research is needed to prove its safety and effectiveness. Always consult your healthcare provider before adding CBD oil to your pain management plan.
National Center for Biotechnology Information (NCBI). Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922297
PubMed. Cannabidiol Use for Fibromyalgia: Prevalence of Use and Perceptions of Effectiveness in a Large Online Survey [Internet]. [cited 2023 Sep 19]. Available from: https://pubmed.ncbi.nlm.nih.gov/33400996
National Center for Biotechnology Information (NCBI). Cannabidiol as a Treatment for Mood Disorders: A Systematic Review: Le cannabidiol comme traitement des troubles de l’humeur: une revue systématique [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385425
National Center for Biotechnology Information (NCBI). Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482919
National Center for Biotechnology Information (NCBI). The Efficacy of Cannabis on Multiple Sclerosis-Related Symptoms [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148011
National Center for Biotechnology Information (NCBI). Therapeutic Applications of Cannabinoids in Cardiomyopathy and Heart Failure [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641267
National Center for Biotechnology Information (NCBI). The effects of acute and sustained cannabidiol dosing for seven days on the haemodynamics in healthy men: A randomised controlled trial [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256118
National Center for Biotechnology Information (NCBI). Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098033
National Center for Biotechnology Information (NCBI). A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039032
PubMed. Cannabinoid therapies in the management of sleep disorders: A systematic review of preclinical and clinical studies [Internet]. [cited 2023 Sep 19]. Available from: https://pubmed.ncbi.nlm.nih.gov/32603954
National Center for Biotechnology Information (NCBI). Adverse effects of cannabidiol: a systematic review and meta-analysis of randomized clinical trials [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608221
National Center for Biotechnology Information (NCBI). Potential Pharmacokinetic Drug-Drug Interactions between Cannabinoids and Drugs Used for Chronic Pain [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443220
National Center for Biotechnology Information (NCBI). Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781714
National Center for Biotechnology Information (NCBI). Cannabidiol as a Treatment for Chronic Pain: A Survey of Patients’ Perspectives and Attitudes [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107012/
National Center for Biotechnology Information (NCBI). A Balanced Approach for Cannabidiol Use in Chronic Pain [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204604
National Center for Biotechnology Information (NCBI). Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851925
National Center for Biotechnology Information (NCBI). 4Therapeutic Effects of Cannabis and Cannabinoids [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK425767
National Center for Biotechnology Information (NCBI). Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371734
National Center for Biotechnology Information (NCBI). Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23685330
National Center for Biotechnology Information (NCBI). Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604178
National Center for Biotechnology Information (NCBI). Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707667
National Center for Biotechnology Information (NCBI). Cannabidiol as a Potential Treatment for Anxiety Disorders [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171
National Center for Biotechnology Information (NCBI). A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/22716160
National Center for Biotechnology Information (NCBI). Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/27767974
National Center for Biotechnology Information (NCBI). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602
National Center for Biotechnology Information (NCBI). Impact of Cannabis, Cannabinoids, and Endocannabinoids in the Lungs [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023687
National Center for Biotechnology Information (NCBI). Molecular Targets of the Phytocannabinoids-A Complex Picture [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345356
National Center for Biotechnology Information (NCBI). Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151231
PubMed. Safety and side effects of cannabidiol, a Cannabis sativa constituent [Internet]. [cited 2023 Sep 19]. Available from: https://pubmed.ncbi.nlm.nih.gov/22129319
Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.
Links and product recommendations in the informationprovided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.
Comments