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Low Platelet Count: Understanding Causes and Tips for Improving Platelet Levels  

By Dr. Nayana Shetty +2 more

Key Highlights: 

  • Understand the importance of platelets and the dangers of low platelet count. 
  • Understand the symptoms of low platelet count, such as petechiae and heavy menstrual bleeding. 
  • Learn when to see a doctor and how low platelet count is diagnosed. 
  • Explore the causes of low platelet count, including enlarged spleen and decreased production. 
  • Discover management options and lifestyle changes for managing low platelet count. 

Introduction 

Platelets play a crucial role in blood clotting, and having inadequate platelet counts can affect our well-being. Their number can decrease due to many factors. This situation is medically known as thrombocytopenia, that is, low platelet count. In this article, we delve into the production, functions, and health issues associated with platelets. We look at how they work, what triggers a low platelet count, and how it’s diagnosed. Plus, we will discuss management options and simple lifestyle changes that may help.

low platelet count

Did you know?

  • Low platelet count (Thrombocytopenia) is associated with an increased risk of bleeding, particularly in severe cases. source: StatPearls
  • Thrombocytopenia can be an early sign of an underlying medical condition, such as leukemia or liver disease. source: StatPearls
  • Thrombocytopenia can be diagnosed through a complete blood count (CBC) test, which measures the number of platelets in the blood. source: StatPearls
  • Treatment options for thrombocytopenia include platelet transfusions, medications, and addressing the underlying cause. source: StatPearls
  • Thrombocytopenia can be managed with regular monitoring and appropriate treatment, leading to improved outcomes for patients. source: StatPearls

What is Low Platelet Count (Thrombocytopenia)? 

Definition 

Low platelet count, medically known as thrombocytopenia, happens when there are less than 150,000 platelets per microliter in our bloodstream. 

Role of platelets in blood clotting 

Platelets help blood to form clots. This process stops heavy bleeding after an injury. Platelets do this by joining together to form plugs in wounded blood vessels. 

Normal platelet count range 

It’s between 150,000 and 450,000 platelets per microliter of blood. 

Symptoms of Low Platelet Count 

In this section, we have enumerated and discussed the various symptoms that may develop in a person with low platelet counts. 

Petechiae 

One key sign of low platelet count is petechiae formation. It’s marked by small, reddish-purple spots on the skin. They appear due to minor bleeding under the skin. 

Bruising 

People with low platelet count may also bruise easily. In medical terms, this is called purpura. A purpura is bigger in size when compared to a petechiae. This is also due to easy minor bleeding of the vessels under the skin. 

Prolonged bleeding from cuts 

Low platelets in the blood could make minor injuries bleed for longer duration. This can slow down wound repair. 

Heavy menstrual bleeding 

For women, heavy flows during periods could be a sign of low platelet count. 

When to See a Doctor? 

Timing is key in handling thrombocytopenia.  

Symptoms that warrant medical attention 

If you notice any symptoms like easy bruising, petechiae, or prolonged bleeding, consult your doctor right away. 

Uncontrolled bleeding as a medical emergency 

If you can’t stop bleeding with basic first-aid like applying pressure to the injury, seek instant medical help. 

To my knowledge, severe internal bleeding may be more likely to occur in those with severe thrombocytopenia (or low platelet count). Bleeding in the brain or gastrointestinal tract might result from thrombocytopenia. Bleeding in the brain is a potentially fatal condition.

Dr. Siddharth Gupta, B.A.M.S, M.D

Causes of Low Platelet Count 

There are many causes of low platelet count which are as follows. 

1. Enlarged spleen (trapped platelets) 

An enlarged spleen, known as splenomegaly, can trap excess platelets. This then lowers their number in the bloodstream. 

2. Decreased production of platelets 

A decrease in platelet production can occur because of issues in the bone marrow, viral infections, or genetic disorders. 

  • Bone marrow problems 

Certain illnesses like leukaemia or aplastic anaemia can disrupt the bone marrow, leading to a fall in platelet production. 

  • Viral infections 

Certain viruses, like hepatitis C or HIV, can lower the production of platelets. 

  • Genetic causes 

Genetic conditions can also cause a drop in platelet production. An example is Wiskott-Aldrich syndrome or May-Hegglin anomaly. 

3. Increased breakdown of platelets 

Sometimes, our bodies might use up or destroy platelets faster than they’re produced. This can lead to thrombocytopenia. There are certain situations where this can happen which are as follows.  

  • Immune system disorders 

Autoimmune diseases like ITP, lupus, or rheumatoid arthritis can incite our immune system to wrongly destroy platelets. 

  • Medications and substances 

Certain drugs can foster platelet destruction or slow down their production. Excessive alcohol intake can have similar effects. 

Your doctor might advise against flossing until your platelet counts stabilise. You are advised to rinse and wash your teeth after every meal. To avoid bleeding gums, use an extra-soft toothbrush. Use hot water to make your toothbrush softer before each usage. Use extreme caution and gentleness when flossing. Steer clear of readily bled areas. Apply petroleum jelly or lip balm to keep lips hydrated and stop them from breaking. Consult your medical team before receiving any dental care.

Dr. Rajeev Singh, BAMS

Diagnosis of Low Platelet Count 

Diagnosis involves a series of tests. These are discussed below.  

1. Physical examination 

During a health check, the doctor checks your skin for bleeding signs. They’ll also feel your abdomen to check for an enlarged spleen. 

2. Medical history 

The doctor will ask you about past illnesses and medication use that may impact your platelet count. 

3. Blood tests 

A complete blood count (CBC) test helps find out the numbers of different blood cells, including platelets. 

4. Ultrasound 

In case an enlarged spleen is suspected, your doctor may perform an ultrasound. This lets them view the organ and gauge its size. 

5. Bone marrow aspiration and biopsy 

The doctor can take fluid (aspiration) or tissue (biopsy) samples from your bone marrow. This can provide extra clues on the cause of your low platelet count. 

Due to its antioxidant qualities, dragon fruit might help people with dengue increase their platelet counts. For this reason, doctors may advise dengue patients to eat dragon fruit. However, there is lack of enough large scale studies to back this up.

Dr. Smita barode, B.A.M.S, M.S.

Management of Low Platelet Count 

Management involves tackling the root cause while managing the symptoms. In many cases, managing the main cause of the low platelet count may help solve the issue. This might involve adjusting medications or treating infections. 

1. Medication adjustments 

If certain medicines are causing your low platelet count, your doctor might change them to limit their bad effects. 

2. Infections  

If a viral infection leads to a low platelet count, your healthcare provider will work on treating the viral infection. 

3. Immune system disorders 

If your body is wrongly attacking platelets due to an immune system disorder, your doctor may prescribe drugs to raise your platelet count and reduce the immune overactivity. 

4. Blood transfusions 

For very low platelet counts, blood transfusions might be needed. These transfusions replace lost blood parts with packed red blood cells or platelets. 

5. Platelet transfusions 

Sometimes, platelet transfusions may help raise very low platelet levels and improve blood clotting. 

6. Medications to increase platelet production 

Medicines that boost platelet production might be prescribed by your healthcare provider to improve blood clotting. 

Lifestyle and Home Remedies 

Some everyday steps may help lower your risks linked to low platelet count and may help boost your overall health. 

Avoiding injuries 

Skip activities that may lead to injury. These include contact sports. Make sure to take all safety precautions. 

Adjusting medications 

Discuss with your doctor about any medicines or supplements that might harm your platelet count. 

Maintaining a healthy lifestyle 

Eat well, exercise regularly, and get enough sleep. This may help keep your immune system strong and your blood cells working well. 

Avoiding alcohol 

Excessive alcohol interferes with bone marrow function and platelet creation. So, cut back or avoid alcohol. 

Complications of Low Platelet Count 

Ignoring a low platelet count can lead to various issues, some of which can be life-threatening. 

Severe bleeding 

A very low platelet count increases your risk of heavy bleeding. This may require urgent medical care. 

Bleeding in the brain 

In severe cases, low platelet counts can cause brain bleeding. If not treated, this can be fatal. 

Prolonged bleeding during surgery 

If you need surgery but have a low platelet count, you might bleed for longer. This can make repair after surgery difficult. 

Screening 

Routine tests and checks may help detect and handle low platelet counts early, which may reduce possible complications. 

Routine blood tests 

Regular blood tests, like CBCs, can detect a low platelet count before it becomes a serious health issue. 

Regular monitoring of high-risk individuals 

If your risk of low platelet count is high because of ongoing health issues, family history, or certain medications, keep taking regular medical tests to track your platelet levels. 

Also Read: How To Increase Platelet Count Naturally

Conclusion 

Knowing how vital platelets are and being aware of the signs, triggers, and management options of a low platelet count can empower you to take charge of your health. Keeping regular check-ups, getting routine tests, and taking steps to reduce the risk will help your healthcare provider and you stay alert to any health issues. If you detect signs of low platelet count or have a family history of clotting problems, discuss with your healthcare provider.  

Frequently Asked Questions (FAQs) 

How can you fix low platelets? 

There are many causes for low platelet count. The management then depends on what’s causing it. Talk to your healthcare provider to find the right solution, be it changing medications, treating infections, or managing immune system issues. 

What is the most common cause of low platelet count? 

There’s no typical cause for a low platelet count. It varies and can be from an enlarged spleen, issues with the bone marrow, viral infections, or genetic causes. 

Should I worry if my platelets are low? 

A slightly low platelet count that’s not causing any signs may not be a big worry. If you do see symptoms or your count is very low, go to your healthcare provider.. 

Is 81 a low platelet count? 

Yes, a platelet level of 81 is considered critically low. The normal range is between 150,000 and 450,000 platelets per microliter in your blood. Talk to your healthcare provider if you have worries about your platelet count. 

How to boost platelet count naturally? 

Foods high in vitamin K, vitamin B-12, iron, and folate may boost platelets. Still, do discuss with your healthcare provider for personalized advice based on your specific needs. 

References: 

  1. National Center for Biotechnology Information (NCBI). Thrombocytopenia [Internet]. [cited 2024 Feb 13]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK542208 
  1. National Center for Biotechnology Information (NCBI). Mechanism Action of Platelets and Crucial Blood Coagulation Pathways in Hemostasis – PMC [Internet]. [cited 2024 Feb 13]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767294 
  1. ScienceDirect. Your Browser is out of date. [Internet]. [cited 2024 Feb 13]. Available from: https://www.sciencedirect.com/science/article/pii/B9780702051012000662 
  1. ScienceDirect. Your Browser is out of date. [Internet]. [cited 2024 Feb 13]. Available from: https://www.sciencedirect.com/science/article/pii/B9781437717389000177 
  1. PubMed. Laboratory testing for platelet antibodies [Internet]. [cited 2024 Feb 13]. Available from: https://pubmed.ncbi.nlm.nih.gov/23757218 

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