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What Is Meningitis? A Detailed Research-Based Overview

By Dr. Nayana Shetty +2 more

Key Highlights: 

  • Meningitis is an inflammation of the protective membranes around the brain and spinal cord. 
  • Viral, bacterial, fungal, parasitic, non-infectious, and chronic forms of meningitis are known. 
  • Symptoms may include fever, stiff neck, headache, rash, and in severe cases, seizures. 
  • Medical professionals diagnose meningitis through clinical examination, lab tests, and imaging. 
  • Management depends on the type and severity of meningitis and may include antibiotics, antiviral medications, or other supportive care. 
  • Vaccinations and certain general tips tip to reduce the chances of getting the infection may be helpful.  

Introduction 

Meningitis is a serious condition. It happens when the protective coverings called meninges, enveloping the brain and spinal cord get inflamed. Usually, various infections like viral, bacterial, fungal, or parasitic trigger it. However, it can also occur due to autoimmune diseases, certain drugs, or an injury. If left untreated, meningitis can lead to serious health problems and even death. 

In this article, we’ll talk about different kinds of meningitis, their signs, how they’re diagnosed, and how to deal with them. Moreover, we’ll discuss the various risk factors, possible complications, how to reduce the chances of getting meningitis, and what to expect for those affected by the condition. It’s very important to understand meningitis so you may spot its symptoms, seek necessary medical help on time, and take steps to keep yourself and your family safe. 

what is meningitis

Did you know?

  • Meningitis can cause symptoms such as fever, headache, stiff neck, nausea, and vomiting. source: cdc.gov
  • Meningitis can be spread through respiratory droplets or throat secretions from person to person. source: cdc.gov
  • Bacterial meningitis requires immediate antibiotic treatment, while viral meningitis usually resolves on its own with rest and fluids. source: healthdirect.gov.au
  • Meningitis can cause serious complications, including sepsis, hearing loss, and long-term neurological problems. source: healthdirect.gov.au
  • Meningitis can be caused by bacteria, viruses, fungi, and parasites. source: healthdirect.gov.au

Types of Meningitis 

It’s crucial to understand various types of meningitis. Each kind behaves differently and needs a particular kind of care. In this part, we’ll break down the six types of meningitis which are as follows.  

1. Bacterial Meningitis 

Bacterial meningitis is an urgent and life-threatening type of meningitis. It’s caused by different bacteria that invade the meninges and cause inflammation. 

Causes 

Bacteria often causing bacterial meningitis are: 

  • Neisseria meningitidis (meningococcus) 
  • Streptococcus pneumoniae (pneumococcus) 
  • Haemophilus influenzae Type B (Hib) 
  • Group B streptococcus 
  • Listeria monocytogenes 

High-Risk Groups 

People who are more prone to get bacterial meningitis are: 

  • Babies and small children 
  • College kids staying in dorms 
  • Soldiers in tight living spaces 
  • People with weak immune systems 
  • People without a spleen 

2. Viral Meningitis 

Viral meningitis is the most common type. It’s caused by viral infections. Generally, it’s less harmful than bacterial meningitis and often resolves on its own.  

Causes 

Viruses often causing this type include: 

  • Non-polio enteroviruses (like coxsackieviruses and echoviruses) 
  • Herpes viruses (Epstein-Barr virus, herpes simplex viruses, varicella-zoster virus) 
  • Influenza virus 
  • West Nile virus 
  • Mumps virus 
  • Measles virus 

High-Risk Groups 

Viral meningitis often affects: 

  • Small kids 
  • Individuals with weak immune systems 

3. Fungal Meningitis 

Fungal meningitis is rare but very serious. It’s caused by fungal infections that reach the meninges. People with poor immunity have a higher risk of getting this type. 

Causes 

Fungi that may cause fungal meningitis include: 

  • Cryptococcus 
  • Histoplasma 
  • Blastomyces 
  • Coccidioides 
  • Candida 

High-Risk Groups 

People vulnerable to fungal meningitis arethose with weak immune systems because of AIDS, cancer, or strong medicines 

4. Parasitic Meningitis 

This type is not common. Parasites infect the meninges causing inflammation. 

Causes 

Parasites often causing this meningitis include: 

  • Angiostrongylus cantonensis 
  • Baylisascaris procyonis 
  • Gnathostoma spinigerum 

High-Risk Groups 

Those at high risk include: 

  • Individuals who eat raw or poorly cooked foods with parasites in them 
  • People exposed to dirt or animal waste contaminated with parasites 

5. Non-infectious Meningitis 

Non-infectious meningitis involves the inflammation of the meninges. Unlike other kinds, infectious agents are not the cause behind them. 

Causes 

Potential causes of this type are: 

  • Cancer 
  • Systemic lupus erythematosus (SLE) 
  • Drugs 
  • Contact with chemicals 
  • Head  injuries 
  • Brain operations 

High-Risk Groups 

Risk factors differ based on the specific cause. They may include: 

  • People are on certain drugs or undergoing brain operations.  
  • Those with a past of autoimmune diseases or cancer 

6. Chronic Meningitis 

Chronic meningitis lasts for a long time. It can persist for weeks or months. 

Causes 

Causes include: 

  • Slow-growing organisms like fungi 
  • Mycobacterium tuberculosis (TB) 
  • Sarcoidosis 
  • Autoimmune conditions 

High-Risk Groups 

People at risk comprise of: 

  • Those with weak immunity 
  • Anyone with tuberculosis 
  • People with autoimmune conditions 

The information below summarizes the various types of meningitis, their causes, and those who are at risk of getting the infection. 

Type Causes High-Risk Groups 
Bacterial Bacteria like Neisseria meningitidis, Streptococcus pneumoniae, etc. Babies, college students, soldiers, those with weak immunity 
Viral Viruses like non-polio enteroviruses, herpesviruses, etc. Small kids, people with weak immune systems 
Fungal Fungi like ryptococcus, istoplasma, etc. People with weak immune systems 
Parasitic Parasites from food or nature like Angiostrongylus cantonensis, etc. People eating contaminated foods, exposed to dirty ground 
Non-infectious Autoimmune conditions, cancer, drugs, contact with chemicals, head harm, brain operation  People with a history of some cancers, autoimmune disorders, taking certain drugs, or exposure to certain chemicals. 
Chronic Slow-growing microbes, TB, autoimmune conditions, sarcoidosis Those with weak immunity, TB, autoimmune problems 

Seizure is a common and unwelcomed outcome of bacterial meningitis. Most seizures begin on the first or second day, and most stop within two days, often seen at the extremes of life.

Dr. Ashish Bajaj, M.B.B.S., M.D.

Symptoms of Meningitis 

Symptoms may vary based on age, infants, children, and adults. 

1. Meningitis in Infants 

Signs in babies are as follows. 

  • Fever 
  • Continuous crying 
  • Being very sleepy or touchy 
  • Difficulty waking up 
  • Poor eating 
  • Stiff neck or body, or jerky movements 
  • A bulging soft spot on the head (fontanel) 

2. Meningitis in Children 

  • In kids, signs may be as follows. Fever 
  • Head pain 
  • Vomiting 
  • Stiff neck 
  • Light sensitivity (photophobia) 
  • Tiredness or sleepiness 
  • Loss of appetite 

3. Meningitis in Adults 

Common signs in adults are as follows. 

  • Fever 
  • Stiff neck 
  • Head pain 
  • Nausea or vomiting 
  • Light sensitivity 
  • Confusion or trouble focusing 
  • Seizures 

Identifying and Differentiating Meningitis Symptoms 

If you or a friend have any of the above signs, you must get medical help right away. Early diagnosis and care are key to lowering the complications linked to meningitis. 

  • Meningitis Rash: The Glass Test 

A rash coming from meningococcal meningitis often signals a more serious illness. Press hard but clear glass on the rash. If the spots don’t disappear, seek immediate medical help, as this may point to serious blood poisoning i.e., overwhelming meningococcal infection in the blood. 

The first symptoms of meningitis are usually fever, vomiting, headache and feeling unwell. Limb pain, pale skin, and cold hands and feet often appear earlier than the rash, neck stiffness, dislike of bright lights and confusion.

Dr. M.G. Kartheeka, MBBS, MD

Risk Factors for Meningitis 

The risk factors for getting meningitis are as follows. 

1. Age 

Babies and small kids have a higher risk for viral and bacterial meningitis. As for teenagers and young adults, they’re more likely to get meningococcal meningitis. 

2. Compromised Immunity 

People with weak immunity due to HIV/AIDS, cancer, or autoimmune conditions, or on medications like chemotherapy, have a higher chance of suffering from meningitis. 

3. Community Living 

Living in crowded places such as college dorms, military bases, or long-term care facilities heightens the chance of developipng certain types of meningitis. That’s especially true for meningococcal meningitis. 

4. Pregnancy 

Pregnant women have an increased risk for listeriosis. It’s a bacterial infection that can lead to meningitis. 

5. Working with Animals 

Farm workers and others working with animals face a higher risk of exposure to Listeria bacteria.  

Diagnosis of Meningitis 

To assess if it’s meningitis, healthcare professionals use physical exams, lab tests, and imaging tests. 

1. Clinical Diagnosis 

The first step may involve: 

  • A physical exam (looking for fever, neck stiffness, rashes, or seizures) 
  • Medical history (looking at possible contact with sick people or risky areas) 

2. Laboratory Tests 

Lab tests useful to diagnose meningitis include: 

  • Blood cultures (to find out what is the causative agent) 
  • Testing cerebrospinal fluid (CSF) the clear liquid that flows in and around the brain and spinal cord. This is obtained via lumbar puncture or spinal tap. 

3. Imaging Tests 

Picture tests can be used to find signs of inflammation or other potential causes: 

  • Computed Tomography (CT) scan of the brain 
  • Magnetic resonance imaging (MRI) scan of the brain 

4. Lumbar Puncture Procedure 

A lumbar puncture or a spinal tap is key to diagnosing meningitis. A needle is inserted into your spinal canal to collect a CSF sample. Doctors then assess this sample for signs of an infection. 

Management of Meningitis 

The way to manage meningitis varies based on the type and how serious the infection is. 

1. Bacterial Meningitis  Management 

Cases need prompt hospital stays and care with IV antibiotics. Other supportive care may be given to manage inflammation and other issues. 

Antibiotics 

Your doctor may prescribe antibiotics based on the specific bacteria causing the infection. These could include: 

  • Penicillin 
  • Ceftriaxone 
  • Vancomycin 
  • Ampicillin 

Adjunct Therapy 

Additional therapies that may be given along with antibiotics include: 

  • Corticosteroids (to reduce swelling) 
  • Anticonvulsants (to stop seizures) 
  • Painkillers (to control pain) 
  • Antipyretics (to reduce fever) 

2. Viral Meningitis  Management 

Viral meningitis often goes away on its own. Still, taking care during this time may help manage symptoms. 

Supportive Care 

Ways to care for viral meningitis include: 

  • Rest 
  • Drinking water 
  • Over-the-counter pain and fever-relieving medications 

3. Fungal Meningitis  Management 

 For fungal meningitis IV antifungal drugs may be given, often followed by oral medicines along with supportive care. 

Antifungal Medications 

Antifungal drugs that may be used for this form include: 

  • Amphotericin B 
  • Fluconazole 
  • Flucytosine 

Please note, before taking these drugs it is advisable to consult your doctor for accurate guidance 

4. Parasitic Meningitis  Management 

Care typically includes drugs that target certain parasites or managing the symptoms of the infection. 

Anthelmintic Medications 

Some drugs which target the parasites that cause this form include: 

  • Albendazole 
  • Mebendazole 
  • Praziquantel 

Please note, before taking these drugs it is advisable to consult your doctor for accurate guidance 

5. Non-infectious Meningitis  Management 

The management of non-infectious kind includes taking care of the root cause, like cancer or autoimmune conditions. These may include drugs or therapies related to the cause. 

Medications and Therapies 

Some ways to manage non-infectious meningitis include: 

  • Corticosteroids (for swelling) 
  • Addressing any root causes (like an autoimmune condition or cancer) 

6. Chronic Meningitis  Management 

The management of chronic meningitis revolves around taking care of the root cause of the  inflammation, like slow-growing organisms or autoimmune conditions. 

Medications and Therapies 

 Management  of chronic type may include: 

  • Long-term use of antifungal drugs (for slow-growing fungal infections) 
  • Managing the root autoimmune conditions 

Here is a summary of management methods of meningitis based on  type. 

Also Read: 18 Simple Home Remedies For Fungal Infections!

Type  Management 
Bacterial IV antibiotics, adjunct therapies (corticosteroids, anticonvulsants) 
Viral Supportive care (rest, hydration, over-the-counter remedies) 
Fungal IV and oral antifungal medications 
Parasitic Anthelmintic medications or symptomatic management 
Non-infectious Tackle root causes, corticosteroids 
Chronic Manage according to root cause (long-term antifungal medications, management of autoimmune disorders) 

Complications of Meningitis 

If not taken care of quickly and properly, meningitis can cause short-term and long-term problems. 

1. Short-Term Complications 

Some of the short-term problems that can arise from meningitis include: 

  • Seizures 
  • Swelling in the brain 
  • Blood clotting issues 
  • Sudden drop in blood pressure (shock) 

2. Long-Term Complications 

Long-term problems can occur, especially in cases of bacterial meningitis: 

  • Loss of hearing 
  • Memory issues 
  • Learning problems 
  • Damage to the brain 
  • Trouble walking or moving  
  • Seizures 

How to reduce chances of getting Meningitis 

Avoiding meningitis involves living healthy, staying clean, and getting vaccinated. 

1. Vaccinations 

Shots may help guard against some forms of meningitis. Some common meningitis vaccines include: 

  • Haemophilus influenzae type b (Hib) vaccine 
  • Pneumococcal conjugate vaccine 
  • Meningococcal vaccines 

2. General Infection Avoidance Measures 

General ways to reduce the spread of infections that may cause meningitis include: 

  • Washing hands often 
  • Staying away from sick people 
  • Good hygiene practices (like not sharing personal items) 

3. Pregnancy and Listeriosis   

During pregnancy, it’s key to avoid foods that may put you at risk for listeria infection. These foods can cause meningitis. Some tips for reducing possible listeriosis during pregnancy include: 

  • Cooking meat thoroughly 
  • Avoiding dairy items not pasteurized 
  • Washing fruits and vegetables well 
  • Safe storage and handling of food 
     

Conclusion 

Meningitis is a life-threatening health problem. It happens due to inflammation of the protective layers around the brain and spinal cord. Depending on the cause, symptoms, and the overall health of the person, it may range from mild to deadly. Fast and suitable help is key to limit problems and help ensure better outcomes. By understanding the different forms, risks, and  management methods, people may take needed steps to  reduce infection, detect disease early, and get appropriate medical care. Always  be aware of meningitis risks. Also, be up to date with the vaccine shots to keep yourself and your loved ones safe.  

Frequently Asked Questions (FAQs) 

How contagious is meningitis? 

Viral and bacterial meningitis can spread through tiny germs spreading into the air from the mouth or nose of an infected person or close contact. Other kinds, such as fungal, parasitic, and non-infectious meningitis, won’t spread. 

Can a person survive meningitis? 

Yes, many may recover from meningitis with suitable care ,but bacterial meningitis can be fatal if not treated promptly. Early medical intervention is crucial. 

How long can you have meningitis without knowing? 

Viral and bacterial meningitis symptoms can appear over several hours or several days. It’s critical to seek medical help once symptoms appear for the best possible outcome. 

What is the difference between bacterial and viral meningitis? 

Bacterial meningitis is caused by bacteria and is usually more severe than viral meningitis. Viral meningitis generally resolves on its own, whereas bacterial meningitis requires swift hospital admission and management with IV antibiotics. 

Can you get meningitis more than once? 

Indeed, one can get meningitis more than once. While after recovering, some people might fight off a specific organism in the future, they could still get infected by other organisms. Proper vaccine shots and avoidance steps are critical to lower the risk of a second attack. 

References: 

  1. National Center for Biotechnology Information (NCBI). Pathogenesis of Meningococcemia [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662350 
  1. Centers for Disease Control and Prevention (CDC). Non-Polio Enterovirus [Internet]. [cited 2023 Sep 19]. Available from: http://www.cdc.gov/non-polio-enterovirus/index.html 
  1. World Health Organization (WHO). Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.who.int/news-room/fact-sheets/detail/meningitis 
  1. Centers for Disease Control and Prevention (CDC). Meningococcal Vaccination [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningococcal/vaccine-info.html 
  1. Centers for Disease Control and Prevention (CDC). Meningococcal Vaccination [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/vaccines/vpd/mening/index.html 
  1. Centers for Disease Control and Prevention (CDC). Prevent <em>Listeria</em> [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/listeria/prevention.html 
  1. Centers for Disease Control and Prevention (CDC). Amebic Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningitis/amebic.html 
  1. Centers for Disease Control and Prevention (CDC). Bacterial Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningitis/bacterial.html 
  1. National Center for Biotechnology Information (NCBI). Corticosteroids for acute bacterial meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23733364 
  1. Centers for Disease Control and Prevention (CDC). Fungal Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningitis/fungal.html 
  1. National Health Service (NHS). Overview – Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.nhs.uk/conditions/meningitis 
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  1. Centers for Disease Control and Prevention (CDC). What is Sepsis? [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/sepsis/what-is-sepsis.html 
  1. National Center for Biotechnology Information (NCBI). Neuroanatomy, Cranial Meninges [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539882 
  1. National Center for Biotechnology Information (NCBI). Bacterial Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470351 
  1. Centers for Disease Control and Prevention (CDC). Meningococcal Vaccination: What Everyone Should Know [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/vaccines/vpd/mening/public/index.html 
  1. Centers for Disease Control and Prevention (CDC). Pneumococcal Vaccination [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/vaccines/vpd/pneumo/index.html 
  1. Centers for Disease Control and Prevention (CDC). <em>Haemophilus Influenzae</em> Type b (Hib) VIS [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/vaccines/hcp/vis/vis-statements/hib.html 
  1. Centers for Disease Control and Prevention (CDC). Signs and Symptoms [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningococcal/about/symptoms.html 
  1. Centers for Disease Control and Prevention (CDC). Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningitis/index.html 
  1. Centers for Disease Control and Prevention (CDC). Viral Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningitis/viral.html 
  1. Centers for Disease Control and Prevention (CDC). Parasitic Meningitis [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningitis/parasitic.html 
  1. Centers for Disease Control and Prevention (CDC). Meningococcal Disease in Other Countries [Internet]. [cited 2023 Sep 19]. Available from: https://www.cdc.gov/meningococcal/global.htm 

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