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Potential Benefits of Beta Alanine: Understanding Its Role in Performance Enhancement

By Dr. Shubham Pandey +2 more

Key Highlights: 

  • Beta-alanine is a non-essential amino acid that increases muscle carnosine levels. 
  • It is proposed to improve athletic performance, particularly in high-intensity, short-duration exercises. 
  • May also aid in body composition and blood sugar management. 
  • Found in animal sources such as poultry and meat, as well as dietary supplements. 
  • Recommended daily intake is between 2 to 5 grams. 
  • Common side effects include tingling (paraesthesia), which can be managed by adjusting dosage. 

Introduction 

To boost your athletic abilities there are loads of athletic enhancers out there. Today, we’re focusing on one that’s grown popular over time. That’s beta-alanine. Numerous athletes and fitness enthusiasts believe it may help them perform better. It’s particularly handy for high-intensity, short-term workouts. But that’s not all. It has potential benefits related to the body shape, brain function, and blood sugar. In this article, we will be discussing beta-alanine in detail. Lastly, we will answer some frequently asked questions regarding this topic.

beta alanine benefits

Did you know?

  • Beta-alanine supplementation has been shown to increase muscle carnosine levels by up to 80%. source: PubMed
  • Beta-alanine supplementation has been shown to improve repeated sprint performance.source: PubMed
  • β-Alanine supplementation can delay the onset of neuromuscular fatigue during intense exercise. source: PubMed
  • β-Alanine supplementation can increase muscle buffering capacity during high-intensity exercise. source: PubMed
  • A study found that β-Alanine supplementation improved cycling performance in trained cyclists. source: NCBI

What is Beta-Alanine? 

Definition 

Beta-alanine is a non-essential amino acid, which means the body makes it naturally, so it’s not essential to your diet.  It is necessary to help make something called carnosine. That’s a molecule that gives your physical output a boost. 

Chemical Structure 

Beta-alanine has an interesting structure. It’s made up of an amino group (-NH2) and a carboxylic acid group (-COOH). Its special status as a beta-amino acid comes from where its amino group sits. It sets it apart from the other alpha-amino acids in proteins. 

Biological Function 

Beta-alanine helps make carnosine in your body when paired with another amino acid, histidine. This combination then gets stored in the muscles and brain. In simple terms, it helps manage muscle acidity during brief, high-intensity workouts.  

How Does Beta-Alanine Work? 

1. Role in Carnosine Synthesis 

As we already mentioned, beta-alanine helps make carnosine with histidine. This lets the body store carnosine in the muscles. The amount of beta-alanine in the muscles often limits carnosine production. You can raise muscle carnosine up to 80% by taking beta-alanine. 

2. Muscle Buffering Capacity 

When you do high-intensity workouts, your muscles produce hydrogen ions. This makes them more acidic. Acidic muscles make it harder for you to work out. They often lead to a feeling of tiredness. Carnosine acts as a buffer against this acidity. It helps you feel less tired and perform at peak levels for longer periods. 

3. Impact on Muscle Endurance 

If you take beta-alanine, your muscle carnosine is said to get a boost. This helps your muscles resist the effects of acidity during tough workouts. As a result, you may be able to push yourself harder for longer and get better results. 

Beta-Alanine and Athletic Performance 

1. Strength Training 

Beta-alanine may be a game-changer. It is proposed to help boost muscle growth and output during resistance training. 

  • Impact on Muscle Growth 

Research suggests that taking beta-alanine might lead to increased lean muscle mass. By boosting the volume of exercise and reducing tiredness, which stimulates the muscles to grow. 

  • Resistance Training Benefits 

Beta-alanine is supposed to provide better results in resistance training. This includes strength, training volume, and time to exhaustion.  

2. Endurance Training 

Beta-alanine is not just for high-intensity, short workouts. It’s proposed to also be useful for endurance training. 

  • Cardiovascular Improvements 

Carnosine, made from beta-alanine, improves nitric oxide production. Nitric oxide improves blood flow and oxygen delivery to muscles. This may enhance your heart health during long workouts. 

  • Time to Exhaustion 

Taking beta-alanine has been linked to more time before fatigue during endurance exercises, like running, cycling, and rowing. That means you might be able to work out for longer periods before feeling tired. 

3. Shorter-Duration Exercises 

Beta-alanine comes into its own during high-intensity, short-duration exercises. Especially when muscle acidosis is stopping you perform at your best. 

  • High-Intensity Interval Training (HIIT) 

Some studies have found that beta-alanine may improve performance and staying power during HIIT sessions. This is probably because it helps buffer muscle acidity during hard workouts. 

  • Sprinting Performance 

It is proposed that both trained and untrained people can sprint better after taking beta-alanine. The increased buffer capacity it offers may help maintain peak sprinting speed before getting tired. 

Other Beta-Alanine Benefits 

Beta-alanine isn’t just for athletes. It may also offer some benefits when it comes to general health and wellbeing. 

1. Body Composition 

As we’ve seen before, taking beta-alanine may increase lean muscle mass. That may also improve body shape. 

  • Fat Loss 

The effects of beta-alanine on fat loss are a little vague. Some studies found no big changes in body shape after taking it. We need more studies to see if beta-alanine impacts fat loss. 

  • Lean Muscle Mass 

Taking beta-alanine may indirectly lead to increased lean muscle mass. This is probably due to better performance and endurance in those taking beta-alanine. 

2. Blood Sugar Management 

Carnosine, made by pairing beta-alanine with histidine, may help control blood sugar. 

  • Insulin Sensitivity 

Carnosine may boost insulin sensitivity. This is proposed to lead to better blood sugar control and a lower risk of type 2 diabetes. However, we need more studies to look at beta-alanine and its impact on insulin sensitivity. 

  • Glucose Uptake 

Carnosine might also play a part in improving glucose uptake in muscle cells. This helps regulate blood sugar levels during and post workouts. We need more research to assess the role of beta-alanine in glucose uptake and confirm these findings. 

3. Brain Health 

Carnosine may have some properties that protect nerve cells.  

  • Cognitive Function 

Animal tests have found that carnosine might improve cognitive function. Memory and learning abilities, in particular. However, we need more studies on humans.  

  • Neuroprotection 

Carnosine has antioxidant properties. That might help protect nerve cells (or neurons) from  damage. By fighting oxidative stress and inflammation in the brain, carnosine might help keep cognitive function in check. It may also help avoid decline tied to aging.  

Top Food Sources of Beta-Alanine 

Your body naturally makes beta-alanine. But you can also get it from certain foods and pills. 

Animal Sources 

Animal-based foods are a good source of beta-alanine. Especially ones rich in carnosine. 

  • Poultry: Chicken and turkey are good sources if you want to get beta-alanine from your diet. 
  • Meat: Red meats, like beef and pork, also carry beta-alanine. 

Dietary Supplements 

If you don’t eat meat or want more beta-alanine, supplements are a good  option. 

  • Forms and Types: Beta-alanine supplements come in pill, tablet, or powder form. Just mix them with water or any other drink. 
  • Combination with Other Supplements: Lots of exercise supplements mix beta-alanine with other ingredients. Like creatine, caffeine, and BCAAs.  

Beta-Alanine Dosage Recommendations 

To get the most from your beta-alanine, consider the proper dosage and timing. 

1. Optimal Daily Intake 

The current evidence suggests you should aim for a daily intake of 2–5 grams. This is the ideal daily amount to enhance your performance and stamina. 

2. Pre-Workout Timing 

Looking to get the max from your beta-alanine for your workout? Try taking it 30 minutes to an hour before your high-intensity, short-term exercises. 

3. Phased Approach 

Are you new to beta-alanine? It might be good to start with a “loading phase”. High daily amounts for several weeks. After that, switch to a “maintenance phase”. A lower daily amount to keep a high level of carnosine in your muscles. 

4. Integrating into a Training Program 

Alongside smart dosage and timing, add beta-alanine to a balanced training program. Cover your bases with proper methods, solid nutrition, and ample recovery time. 

It is to be noted that if you are planning on taking beta-alanine supplements for any of the above-mentioned potential health benefits, do so after consulting your healthcare professional. Never self-administrate.  

Safety and Side Effects of Beta-Alanine 

Beta-alanine isn’t without its drawbacks. As with any supplement, it’s crucial to consider the possible risks and side effects tied to its use. 

Common Side Effects 

Some people may feel tingling or flushed after taking beta-alanine supplements. Larger doses tend to cause this more often. 

  • Paraesthesia 

Paraesthesia, or tingling sensation, is a common side effect of taking beta-alanine. This tends to happen to the face, neck, and back of the hands. You can manage it by adjusting your dosage and how often you take it. 

  • Managing Side Effects 

Reducing side effects is as simple as altering the dosage and how often you take it. Begin with smaller doses and slowly build up as you get used to it. 

Potential Risks 

Despite its potential benefits, it’s always important to play it safe. Always consult a healthcare provider before starting any supplement regimen especially if you’re on medication, pregnant, breastfeeding, or have a pre-existing condition. Never self-administrate.  

  • Long-Term Use Implications 

At the moment, the long-term implications of beta-alanine are a question mark. It’s seen as safe for short-term use based on current evidence. However, further research is needed to confirm its safety for long-term use. 

  • Contraindications 

Beta-alanine needs more safety data for specific groups. For now, it’s not recommended for children, pregnant or breastfeeding individuals, or those with pre-existing medical conditions. Always ask a healthcare professional first.  

Interaction with Other Sports Supplements 

Beta-alanine may be mixed with other sports supplements like sodium bicarbonate and creatine to increase its benefits. 

1. Sodium Bicarbonate 

Like beta-alanine, sodium bicarbonate helps beat down acid build-up in muscles during high-intensity exercise. Research shows that teaming these two may boost workout performance even more. Especially when muscle acidosis is affecting performance. 

2. Creatine 

Creatine helps increase energy in muscles and improve exercise performance. When combined with beta-alanine, these two is said to work together to boost performance, strength, and lean muscle mass. 

3. Branched-Chain Amino Acids (BCAAs) 

Beta-alanine and BCAAs have different roles in the body — with beta-alanine focusing on muscle carnosine levels and BCAAs promoting muscle repair and growth — but combining them may optimise overall athletic performance and recovery. 

Again, always run it with your doctor before combing or trying out any new supplements and never self-administrate.  

Conclusion 

Beta-alanine is a supplement that holds a promise of potential benefits. These benefits are particularly pronounced in athletic performance and high-intensity exercise. Carnosine synthesis from beta-alanine may improve muscle buffering capacity. This leads to improved performance, increased endurance, and reduced muscle fatigue. 

However, keep in mind that any form of supplementation should be done with care and under the advice of a healthcare professional. Maximising the benefits while minimising potential risks requires good knowledge of correct dosages, timing, and integration with other training practices. 

In the end, beta-alanine has great potential for those looking to raise their game in athletics or fitness. Always keep your healthcare professionals in the loop before incorporating any supplement into your daily routine.  

Frequently Asked Questions (FAQs) 

Is beta-alanine safe for everyone? 

While it’s generally safe for healthy people, certain people are advised against taking beta-alanine. These include children, pregnant or breastfeeding women, and those with pre-existing health conditions. A healthcare professional should always be consulted first. 

How long does it take to see the benefits of beta-alanine supplementation? 

The time it takes to see improvements varies based on the person and the nature of the exercise. As a general rule, it’s suggested to supplement with beta-alanine for at least two weeks before expecting improvements in athletic performance. 

Can I take beta-alanine with other supplements? 

You can combine beta-alanine safely with sodium bicarbonate, creatine, or BCAAs as part of a well-rounded athletic performance and recovery plan. Just remember to consult with a healthcare professional before adding any new supplements to your regime. Never self-administrate.  

Are there any natural ways to increase beta-alanine levels? 

Yes, you can naturally increase your beta-alanine levels by eating foods high in carnosine like poultry and meat. However, to significantly bring up the levels of carnosine in muscles and maximise athletic performance, taking supplements might be necessary. Always consult your doctor before taking a supplement.  

Does beta-alanine cause muscle growth similar to creatine? 

While beta-alanine doesn’t directly result in muscle growth like creatine does, it does increase workout performance, endurance, and delayed muscle fatigue. This indirect boost may potentially lead to increased muscle mass and strength, thanks to consistent training. 

References:  

  1. National Center for Biotechnology Information (NCBI). Acid-base balance during exercise [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/7016549 
  1. National Center for Biotechnology Information (NCBI). Effect of beta-alanine supplementation on muscle carnosine concentrations and exercise performance [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/20091069 
  1. National Center for Biotechnology Information (NCBI). Effect of beta-alanine, with and without sodium bicarbonate, on 2000-m rowing performance [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23535873 
  1. National Center for Biotechnology Information (NCBI). Effect of carnosine and anserine on action of isolated frog muscles [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/13095299 
  1. National Center for Biotechnology Information (NCBI). Effect of β-alanine plus sodium bicarbonate on high-intensity cycling capacity [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/21407127 
  1. National Center for Biotechnology Information (NCBI). Effect of β-alanine supplementation on muscle carnosine concentrations and exercise performance [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/20479615 
  1. National Center for Biotechnology Information (NCBI). Effects of β-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/19210788 
  1. National Center for Biotechnology Information (NCBI). Effects of beta-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/19210788 
  1. National Center for Biotechnology Information (NCBI). Effects of beta-alanine supplementation on performance and body composition in collegiate wrestlers and football players [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/21659893 
  1. National Center for Biotechnology Information (NCBI). Effects of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/16868650 
  1. National Center for Biotechnology Information (NCBI). Effects of beta-alanine supplementation on performance and body composition in collegiate wrestlers and football players [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/21659893 
  1. National Center for Biotechnology Information (NCBI). Effects of Six Weeks of β-alanine Administration on VO(2) max, Time to Exhaustion and Lactate Concentrations in Physical Education Students [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/22973486 
  1. National Center for Biotechnology Information (NCBI). Glycation, ageing and carnosine: are carnivorous diets beneficial? [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/15955546 
  1. National Center for Biotechnology Information (NCBI). International society of sports nutrition position stand: Beta-Alanine – PMC [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501114 
  1. National Center for Biotechnology Information (NCBI). Muscle carnosine metabolism and beta-alanine supplementation in relation to exercise and training [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/20199122 
  1. National Center for Biotechnology Information (NCBI). Oral nutritional supplement fortified with beta-alanine improves physical working capacity in older adults: a randomized, placebo-controlled study [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23832078 
  1. National Center for Biotechnology Information (NCBI). Short-duration beta-alanine supplementation increases training volume and reduces subjective feelings of fatigue in college football players [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/19083385 
  1. National Center for Biotechnology Information (NCBI). Systematic review of compression following treatment for varicose veins [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25833417 
  1. National Center for Biotechnology Information (NCBI). The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/16554972 
  1. National Center for Biotechnology Information (NCBI). Timing, optimal dose and intake duration of dietary supplements with evidence-based use in sports nutrition – PMC [Internet]. [cited 2024 Jun 20]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545206 
  1. National Health Service (NHS). Treatment – Varicose veins [Internet]. [cited 2024 Jun 20]. Available from: https://www.nhs.uk/chq/pages/2610.aspx?categoryid=72 

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