"MedicalWebPage", "FAQPage"

Get more insightful and

helpful tips to

treat Diabetes for FREE

Want an ad free reading experience?

Download PharmEasy App

Banner Image

Register to Avail the Offer

Send OTP

By continuing, you agree with our Privacy Policy and Terms and Conditions

Success Banner Image
Advertisement
Advertisement

Magnesium Deficiency: Understanding Causes, Signs, and Solutions

By Dr. Nayana Shetty +2 more

Key Highlights: 

  • Magnesium is an essential nutrient for various bodily functions. 
  • Deficiency can be caused by inadequate diet or health conditions. 
  • Symptoms include muscle cramps, anxiety, fatigue, and high blood pressure. 
  • Diagnosis typically involves assessment of dietary intake and blood tests. 
  • Approaches to addressing deficiency include dietary changes and supplements. 

Introduction 

Magnesium is a vital nutrient key to many body processes. But worldwide, a lack of magnesium is common. This deficiency can harm your health. It may also cause symptoms and serious outcomes if left unchecked. 

This article aims to shed light on magnesium deficiency. We want to help you know why it happens and spot the signs. Plus, we’ll share ways to tackle this often ignored problem. We’ll walk you through risk factors, food sources, ways to spot a deficiency, supplement options, and life changes that may help you reduce deficiency.  

magnesium deficiency

The Importance of Magnesium in the Human Body 

We need this important mineral, magnesium, for many functions which are as follows.  

  • Energy production 
  • Muscle and nerve functions 
  • Bone and teeth building 
  • Protein production 
  • DNA replication 
  • Regulation of other key nutrients like calcium and potassium 

Taking in enough magnesium is key to staying healthy. It may reduce health problems tied to a deficiency. 

Magnesium Deficiency Causes and Risk Factors 

Many factors can cause a lack of magnesium in your body. They are listed below.    

  • People who often eat a diet low in magnesium. 
  • Those suffering from gut disorders like Crohn’s disease, celiac disease, and regional enteritis. 
  • People who lose lots of magnesium in their urine and sweat owing to gene disorders or too much alcohol consumption. 
  • Women who are pregnant or nursing. 
  • Hospital patients 
  • People with parathyroid disorders and hyperaldosteronism. 
  • Those with type 2 diabetes 
  • Elderly people 
  • People who are on certain medications, such as proton pump inhibitors, diuretics, bisphosphonates, and antibiotics. 

Magnesium Deficiency Symptoms 

Symptoms of magnesium deficiency can show up in many ways. They can range from mild to severe symptoms. They are described below.  

1. Muscle Twitches and Cramps 

Common signs of magnesium shortage are muscle twitches and cramps. These discomforting feelings can appear in any muscle in your body. They can range from mild to disabling. 

Causes of Muscle Twitches Due to Magnesium Deficiency 

Having too little magnesium can lead to muscle twitches and cramps in the following ways described below. 

  • By disrupting the balance of electrolytes in your body. 
  • By affecting the handling of calcium in muscle cells. 
  • By affecting nerve signal sending and muscle clenching. 
     

How Magnesium Affects Muscle Function? 

Magnesium is vital in controlling muscle contraction and relaxation. It directs the flow of calcium ions in and out of cells, which causes muscle contractions to start. When you are short on magnesium, muscle cells may clash. This can cause painful spasms and cramps. 

2. Mental Health Conditions 

Magnesium shortage has been tied to many mental health troubles like depression, anxiety, and mood disorders. 

Magnesium Deficiency and Depression 

Lack of magnesium links to depression due to its key role in controlling neurotransmitter production and handling. Magnesium is vital for making serotonin. This is a neurotransmitter that affects our moods. If there’s not enough magnesium, serotonin production may falter. This could lead to a low mood.  

Anxiety and Magnesium Deficiency 

Anxiety is another common sign of lacking magnesium. Similar to depression, anxiety can stem from an imbalance in neurotransmitters, including serotonin, affected by magnesium levels. Also, magnesium has a role in controlling our stress response system, and a shortage may make you more sensitive to stress, leading to increased anxiety symptoms. 

Magnesium’s Role in Brain Health 

Magnesium is central to proper brain working. It protects and maintains neuron health. It also supports cognitive functions like memory and learning. Being short on this nutrient may help trigger neurological and mental health disorders. This highlights why maintaining enough magnesium is key for good brain health.   

3. Osteoporosis 

Osteoporosis is a disease marked by weak bones. This increases the chance of fractures. Lack of magnesium is linked to getting osteoporosis. The mineral has a key role in keeping bones healthy. 

The Role of Magnesium in Bone Health 

Magnesium aids bone health in the following ways. 

  • Helping the uptake of calcium, a key nutrient for strong bones. 
  • Helping with bone remodeling, the process where new bone replaces old bone. 
  • Supporting hormone control, such as parathyroid hormones and vitamin D, which affect bone metabolism. 

Magnesium Deficiency and Bone Deterioration 

Too little magnesium can lead to bone breakdown by affecting the regulation of calcium and disrupting the balance of bone remodeling. This can fuel a higher risk of osteoporosis and bone fractures, especially in older adults and those suffering from extended magnesium deficiency. 

4. Fatigue and Muscle Weakness 

Tiredness and weak muscles are common signs of a lack of magnesium. These symptoms might block daily tasks and reduce your overall way of life. 

How Magnesium Affects Energy Production? 

Magnesium is vital for energy production. It helps change food into usable power. When magnesium levels are low, your body may not produce enough energy. This could lead to feeling tired and weak. 

Identifying Fatigue Linked to Magnesium Deficiency 

It’s key to note that there can be many causes of fatigue. The lack of magnesium is one. Meet a healthcare provider to investigate the cause and how to manage it.  

5. High Blood Pressure 

High blood pressure, or hypertension, is a serious issue. It can raise the chance of heart disease and stroke. Lack of magnesium is linked to a higher risk of getting high blood pressure. 

Magnesium’s Role in Blood Pressure Regulation 

Magnesium plays a key role in controlling blood pressure by impacting the release of vasodilatory hormones and modulating vessel tone. If there’s not enough magnesium, blood vessels might constrict. This could lead to higher blood pressure. 

Managing Blood Pressure with Magnesium 

Ensuring enough intake of magnesium along with other healthy life habits might help control and maintain healthy blood pressure levels. If you’re dealing with high blood pressure or at risk, talk with a healthcare provider about your magnesium intake and any needed steps. 

6. Asthma 

Asthma is a long-term lung disease marked by inflamed airways and trouble breathing. Lack of magnesium has been linked to a raised chance of getting asthma and worsening its symptoms. 

The Connection Between Magnesium and Asthma 

Magnesium has a key role in controlling bronchial smooth muscle tension, which affects airflow and breathing. When magnesium levels drop, airways may get more narrow, making it harder for people with asthma to breathe. 

Magnesium’s Impact on Respiratory Health 

Studies suggest that maintaining enough magnesium could help manage asthma symptoms and improve lung health. Getting enough magnesium, whether through diet or supplements, might help those with asthma or other breathing issues. 

Also Read: Magnesium Rich Fruits: A Research-Based Guide to Healthier Choices

Magnesium Deficiency Diagnosis and Recommended Daily Allowance (RDA) 

Detecting the lack of magnesium can be difficult due to the hard task of correctly measuring magnesium in the body. In the United States, healthcare providers often judge an individual’s magnesium status based on their diet. 

How to Test for Magnesium Deficiency? 

Although blood tests can yield some insights into magnesium amounts, they might not correctly show a person’s magnesium status. This is due to the body’s fast handling of this mineral. More specific tests might offer a clearer view of a person’s magnesium levels, but these are not commonly used in everyday medical practice. 

Magnesium RDA for Adults 

The National Institutes of Health advises these daily intake amounts of magnesium for adults: 

  • 19-30-year-old men: 400 mg 
  • Men over 30: 420 mg 
  • 19-30-year-old women: 310 mg 
  • Women over 30: 320 mg 

Pregnant women who are breastfeeding might need a bit more magnesium to support their higher requirements during these times. 

Magnesium-rich Foods and Absorption Tips 

Dietary sources of magnesium include a variety of whole foods, such as nuts, legumes, whole grains, and green leafy vegetables. Incorporating these magnesium-rich foods into your daily diet may help ensure that you meet your daily magnesium needs. 

Foods High in Magnesium 

Here are some examples of foods that are high in magnesium: 

  • Pumpkin seeds 
  • Chia seeds 
  • Nuts, especially almonds, cashews, peanuts 
  • Spinach 
  • Black beans 
  • Edamame 
  • Peanut butter 
  • Whole wheat bread 
  • Avocado 
  • Potato 
  • Rice 
  • Yogurt 

Tips for Improving Magnesium Absorption through Diet 

Several nutrients and conditions can affect magnesium absorption in your body. To optimize your intake, you may consider the following strategies. 

  • Limit or avoid calcium-rich foods, such as dairy products, within two hours of eating magnesium-rich foods. 
  • Avoid high-dose zinc supplements 
  • Manage any vitamin D deficiencies 
  • Eat raw vegetables whenever possible to maximize mineral intake 
  • Quit smoking, as it can interfere with nutrient absorption 

Magnesium Supplements 

Individuals having trouble getting their needed magnesium through diet might need to turn to supplements. Magnesium supplements come in various forms and dosages. They offer more benefits than just addressing a shortage. These are to be incorporated into your daily routine under your doctor’s guidance. 

Health Benefits of Magnesium Supplementation 

Along with managing deficiency, magnesium supplements are tied to several potential health benefits, which are as follows.  

  • Blood Pressure Management 

Magnesium supplements may help to lower blood pressure. 

  • Sleep Improvement 

Supplemental magnesium has links to better sleep quality. Some people also reported less insomnia. This was especially true for those with restless leg syndrome. 

  • Mood Enhancement 

Taking magnesium supplements is linked to better mood. Users reported fewer signs of feeling down and anxious. 

  • Blood Sugar Control 

Some research hints that taking magnesium supplements may better blood sugar control. It could also help with how sensitive to insulin people with type 2 diabetes or those on the verge of diabetes are. 

  • Heart Disease Risk Reduction 

Magnesium supplements might reduce the risk of heart disease and related problems. These include abnormal heart rates, though more research is needed to confirm this link. 

  • Migraine Alleviation 

Taking magnesium has helped some people reduce how often and strong the migraine headaches are. 

For all the above benefits more research is needed and always discuss with your doctor before incorporating them in your routine. 

Also Read: Magnesium Rich Foods: Your Ultimate Guide to Essential Nutrition

Side Effects and Risks of Magnesium Supplementation 

While generally safe within the advised doses, magnesium supplements can cause side effects in some people. Potential side effects include digestive issues such as diarrhea, cramping, and nausea. 

People with kidney or heart issues should talk to their healthcare provider before using magnesium supplements. Some steps may be needed to reduce possible risks. 

  • Choosing the Right Magnesium Supplement 

Different forms of magnesium supplements exist. Some get absorbed by the body more easily than others. Consider picking supplements that contain magnesium citrate, magnesium lactate, magnesium chloride, or magnesium malate. These forms tend to provide better absorption. 

Always consult with your healthcare service giver before starting to use any magnesium supplement. This ensures it’s safe and fits your unique needs. 

  • Recommended Magnesium Supplement Dosage 

Adult daily magnesium supplement dosage recommendations are generally between 200 and 400 mg, depending on individual factors and the specific supplement being used. Consult with your healthcare provider to determine the appropriate dosage for your circumstances. If you are pregnant or breastfeeding, consult with your healthcare provider for guidance on magnesium supplementation during these periods. Do not self-medicate. 

Ad* You May Also Explore: Pharmeasy Calcium Magnesium Vitamin D3 & Zinc Tablets

Tips for Reducing Magnesium Deficiency 

Approaches to addressing magnesium deficiency typically involve a combination of dietary changes, supplementation, and lifestyle modifications. 

1. Dietary Changes 

Adding foods high in magnesium to your daily diet may boost your magnesium levels and overall health. Whole grains, legumes, nuts, seeds, and green leafy vegetables are all rich in this must-have mineral. 

2. Magnesium Supplementation 

For people who keep having magnesium deficiencies or find it hard to get what they need from food alone, taking magnesium supplements may help. Meet with a healthcare provider to find the best form and dosage for your special needs. 

3. Increasing Magnesium Absorption through Lifestyle Changes 

Making some changes to your lifestyle may increase your body’s uptake of magnesium. Try eating fewer calcium-loaded foods near meals high in magnesium. Also, avoid taking too much zinc. Treat any vitamin D deficiencies and eat more raw veggies. Lastly, try to quit smoking. 

Conclusion 

Lack of magnesium is a common, yet often ignored, issue that can bring a wide range of symptoms and issues. When you know the causes and risk factors tied to being short on magnesium, you may be able to take the first steps to making sure you’re getting this much needed mineral. 

Eat more foods loaded with magnesium, consider supplements when needed, and make lifestyle changes to improve absorption of magnesium. This may help you keep optimal magnesium levels. It will also support overall health and well-being. 

Frequently Asked Questions (FAQs) 

How can I tell if I have a magnesium deficiency? 

Identifying if you lack magnesium can be tough, as signs can be slight or vague sometimes. If you suspect being deficient of magnesium, meet with a healthcare provider. They can check your diet, do a body checkup, and order the right tests. 

Why do we need magnesium in our body? 

Magnesium is an essential nutrient that plays a vital role in many processes inside us. These include producing energy and controlling muscle and nerve functions, bone and teeth growth, protein production, and DNA replication. Keeping enough magnesium levels is key for overall health and well-being. 

What are some common causes of magnesium deficiency? 

Common causes of a lack of magnesium include a poor diet, gut problems that affect absorption, urinating or sweating out too much magnesium, pregnancy, age, and certain medicines. 

Can magnesium deficiency be treated with just dietary changes? 

While changing your diet may help improve magnesium levels, some people might need supplements to manage the deficiency. Meet with a healthcare provider to find the best approach for you. 

How much magnesium should I take in a supplement? 

Daily doses of magnesium supplements are generally between 200 and 400 mg. It depends on a person’s factors and the supplement being used. Meet with your healthcare provider to find the right dose for you. 

References: 

  1. ScienceDirect. Special Focus Issue: Cardiovascular Health Promotion [Internet]. [cited 2024 Jan 10]. Available from: https://www.sciencedirect.com/science/article/pii/S0735109718345601 
  1. ScienceDirect. The Use of Multivitamin/Multimineral Supplements: A Modified Delphi Consensus Panel Report [Internet]. [cited 2024 Jan 10]. Available from: https://www.sciencedirect.com/science/article/pii/S0149291818300894 
  1. National Center for Biotechnology Information (NCBI). Hypomagnesemia [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK500003 
  1. National Center for Biotechnology Information (NCBI). Magnesium Status and Stress: The Vicious Circle Concept Revisited [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761127 
  1. National Center for Biotechnology Information (NCBI). The Effects of Magnesium Supplementation on Subjective Anxiety and Stress—A Systematic Review [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452159 
  1. National Center for Biotechnology Information (NCBI). An update on magnesium and bone health [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313472 
  1. National Center for Biotechnology Information (NCBI). Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/27402922 
  1. National Center for Biotechnology Information (NCBI). Serum Magnesium and Vitamin D Levels as Indicators of Asthma Severity [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080508 
  1. National Center for Biotechnology Information (NCBI). The Role of Hypomagnesemia in Cardiac Arrhythmias: A Clinical Perspective [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598104 
  1. PubMed. Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials [Internet]. [cited 2024 Jan 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/27402922 
  1. National Center for Biotechnology Information (NCBI). Magnesium in Prevention and Therapy [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26404370 
  1. National Center for Biotechnology Information (NCBI). Magnesium in man: implications for health and disease [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25540137 
  1. National Center for Biotechnology Information (NCBI). Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786912 
  1. National Center for Biotechnology Information (NCBI). Beneficial Role of Mg 2+ in Prevention and Treatment of Hypertension [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016150 
  1. PubMed. Changes of Blood Pressure and Hemodynamic Parameters after Oral Magnesium Supplementation in Patients with Essential Hypertension-An Intervention Study [Internet]. [cited 2024 Jan 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/29738504 
  1. PubMed. The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials [Internet]. [cited 2024 Jan 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/28724644 
  1. PubMed. The Effects of Magnesium Supplementation on Blood Pressure and Obesity Measure Among Type 2 Diabetes Patient: a Systematic Review and Meta-analysis of Randomized Controlled Trials [Internet]. [cited 2024 Jan 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/32385715 
  1. PubMed. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis [Internet]. [cited 2024 Jan 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/33865376 
  1. National Center for Biotechnology Information (NCBI). Association of Magnesium Intake With Sleep Duration and Sleep Quality: Findings From the CARDIA Study [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180951 
  1. National Center for Biotechnology Information (NCBI). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703169 
  1. National Center for Biotechnology Information (NCBI). Magnesium and depression [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/27910808 
  1. National Center for Biotechnology Information (NCBI). Efficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: a randomized, equivalent trial [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/19271419 
  1. National Center for Biotechnology Information (NCBI). Role of magnesium supplementation in the treatment of depression: A randomized clinical trial [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28654669 
  1. National Center for Biotechnology Information (NCBI). Magnesium and type 2 diabetes [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549665 
  1. National Center for Biotechnology Information (NCBI). Oral magnesium supplementation in type II diabetic patients [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25405132 
  1. National Center for Biotechnology Information (NCBI). A systematic review and meta-analysis of randomized controlled trials on the effects of magnesium supplementation on insulin sensitivity and glucose control [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/27329332 
  1. National Center for Biotechnology Information (NCBI). Circulating magnesium levels and incidence of coronary heart diseases, hypertension, and type 2 diabetes mellitus: a meta-analysis of prospective cohort studies [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606028 
  1. National Center for Biotechnology Information (NCBI). Dietary Magnesium and Cardiovascular Disease: A Review with Emphasis in Epidemiological Studies [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852744 
  1. National Center for Biotechnology Information (NCBI). Effect of magnesium supplementation on type 2 diabetes associated cardiovascular risk factors: a systematic review and meta-analysis [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28150351 
  1. PubMed. Magnesium and Cardiovascular Disease [Internet]. [cited 2024 Jan 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/29793664 
  1. PubMed. Magnesium in Prevention and Therapy [Internet]. [cited 2024 Jan 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/26404370 
  1. National Center for Biotechnology Information (NCBI). Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25916335 
  1. National Center for Biotechnology Information (NCBI). Magnesium in Migraine Prophylaxis-Is There an Evidence-Based Rationale? A Systematic Review [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29131326 
  1. National Center for Biotechnology Information (NCBI). The Importance of Magnesium in Clinical Healthcare [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637834 
  1. National Center for Biotechnology Information (NCBI). Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best? [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29679349 
  1. National Center for Biotechnology Information (NCBI). Intestinal Absorption and Factors Influencing Bioavailability of Magnesium-An Update [Internet]. [cited 2024 Jan 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652077 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

You may also like

Subscribe
Notify of
guest
0 Comments
Inline Feedbacks
View all comments