Tyramine Rich Foods: Understanding the Impact on Your Health
By Dr. Nayana Shetty +2 more
Medically reviewed by Dr. Nayana Shetty
Last updated: Apr 17, 2024Click to rate this article!
[Total: 4 Avg: 5]
Get more insightful and
helpful tips to
treat Diabetes for FREE
Register to Avail the Offer
Send OTPBy continuing, you agree with our Privacy Policy and Terms and Conditions
By Dr. Nayana Shetty +2 more
Medically reviewed by Dr. Nayana Shetty
Last updated: Apr 17, 2024Table of Contents
Certain food types can stir up health issues for some people. One’s diet can impact their health tremendously. One such component of the diet is tyramine. This stuff might impact your health, more so if you catch migraines easily or use certain pills. It’s key to learn about the task of tyramine-rich foods in your meals and how to bring about the right diet tweaks.
In this blog, we’ll look at tyramine uses, what tyramine does, its natural sources, tyramine rich foods and what it does to health. We’ll also delve into the tie between tyramine and monoamine oxidase inhibitors (MAOIs). We’ll examine the reach of tyramine rich foods on headaches and blood pressure balance. Lastly, we’ll talk about food types to keep away from or lessen to hold to a low-tyramine diet.
Tyramine is formed from the amino acid called tyrosine. This acid forms an important link for proteins. Tyramine does many tasks in the body, one being blood pressure control. Most of the time, tyramine is harmless, but it can lead to health issues in specific events.
Tyramine falls under the large family of compounds known as monoamines. Among them are brain chemicals like dopamine and serotonin. Its form is close to these brain chemicals and helps with signal passing within the nerves.
Certain food types, especially those that go through aging or brewing steps, house tyramine. It is seen often in aged cheeses, cured meats, soy items, wine, and some aged veggies.
As food ages and brews, proteins break down into smaller parts like tyramine. For some foods, tyramine amounts soar during the aging step. This causes high tyramine levels in the end product.
Did you know?
Tyramine is usually present in our bodies and it’s mostly harmless. But too much of it can spark health issues. This is more common in people who react intensely to its effects or are on certain pills.
Monoamine oxidase is an enzyme in the body that degrades monoamines like dopamine, noradrenaline, tyramine, serotonin, etc. Monoamine oxidase inhibitors (MAOIs) inhibit the monoamine oxidase thus increasing the levels of monoamines and were made to handle mental issues like depression and worry. These pills work well but can cross paths with tyramine. This can result in bad side effects that could be damaging.MAOIs prevent the enzyme from breaking tyramine down in the body. Thus, those on MAOIs risk high tyramine levels in their blood. This could result in unwanted effects like a sudden blood pressure rise, also known as a hypertensive crisis. Now if someone using an MAOI eats ftyramine rich foods, there can be a risky build-up of tyramine. High levels could then lead to serious health problems, such as a rise in blood pressure. This could result in a stroke, heart attack, or other life-threatening issues.
Tyramine has been tied to migraines and headaches for some people. We don’t fully understand why just yet. However, it may be that certain substances released in response to tyramine may lead to the expansion and shrinking of vessels in the brain that may set off migraines. Therefore, by following a diet low in tyramine, one can reduce the risk of getting migraines.
As noted before, tyramine helps keep blood pressure in check by pushing out chemicals that make blood vessels expand and contract. But, if tyramine levels in the body get too high, it could lead to sudden blood pressure spikes. This could be bad news, more so in people who already have high blood pressure issues. Thus, monitoring the intake of tyramine via diet is of paramount importance.
Some people might be more sensitive to tyramine than others. This sensitivity might be due to genes, existing health issues, or other causes we don’t fully understand as of now.
People who are sensitive to tyramine might feel a range of things, like headaches, migraines, fast heartbeat, and flushing. High tyramine levels in the body trigger these feelings. This could come from eating foods loaded with tyramine.
If you think you might be sensitive to tyramine, it’s crucial to talk to a healthcare expert. They can help figure out why you have those symptoms. They might suggest sticking to a low-tyramine diet to cut down the risk of a reaction. They can guide you on food choices and other options that are right for your specific needs and likes.
Here’s a quick summary of the above-mentioned points:
| Risk Factor | Symptoms | Management |
| MAOI treatment | Sudden blood pressure rise | Watch and limit tyramine intake |
| Excess dietary intake | Migraines raise blood pressure | Low-tyramine diet |
| Tyramine sensitivity | Rapid heartbeat, flushing | Guidance from healthcare experts |
Based on my observations, aged, matured, and fermented foods such as pickles are a great source of tyramine. Though your body can produce tyramine, there are no side effects if you indulge in external sources of tyramine.
Dr. Siddharth Gupta, B.A.M.S, M.D
Knowing foods high intyramine will help people pick which ones to stay away from or limit in their diet. Below, we’ll show you a list of high, moderate, and low or no tyramine foods.
Food can be divided into three big groups based on their tyramine levels: high, moderate, and low or no.
These include:
These include:
These include:
Based on my observations, people who are on Monoamine Oxidase Inhibitors (MAOI) medications must avoid foods that are rich in tyramine. These medications might be useful in symptomatic relief of diseases like depression, infections, etc. Your body may not be able to process tyramine in a good way while on these medications. Therefore, you must avoid tyramine-rich foods while on MAOI medications.
Dr. Rajeev Singh, BAMS
To better track your tyramine intake, take note of the following foods to steer clear of or limit:
Tyramine rich foods contain protein that include aged cheeses like cheddar or blue cheese, cured meats, salami, and smoked fish. It’s key to eat these sparingly or not at all if you’re trying to limit your tyramine intake.
Overripe bananas and avocados, along with some veggies like eggplant and raspberries can also carry lots of tyramine. Aim for fresh produce to keep tyramine levels low.
Alcoholic drinks, like beer and red wine, can have different tyramine levels. Some coffee or tea drinks may also carry tyramine. It’s best to drink alcohol sparingly and opt for decaf versions of your favorite drinks if you’re concerned about tyramine intake.
Here’s a quick heads-up on the next box:
| Tyramine Content | Food Examples |
| High tyramine | Aged cheeses, cured meats |
| Moderate tyramine | Dairy, chocolate, fruits/veggies |
| Low or no tyramine | Fresh meats, fruits, veggies |
Also Read: Is Brie Cheese Healthy? A Comprehensive Nutritional Analysis
If a healthcare provider has suggested you stick to a low-tyramine diet, follow these steps to make the change smoother:
Here’s a meal plan sample including low-tyramine foods:
Breakfast, lunch, and dinner ideas
If you think a low-tyramine diet might be good for you, talk about it with a dietitian or a healthcare provider. They can help you build a food plan that fits you.
Have a look at the next box:
| Tips for a Low-Tyramine Diet |
| Limit intake by picking fresh and non-aged foods |
| Choose low tyramine meal plans |
| Seek professional support before initiating anything on your own. |
Knowing the role of tyramine in health and where high-tyramine foods come from can help people make smart food choices. For those who react strongly to tyramine or are on MAOIs now, following a low-tyramine diet is key to avoiding the risk of harmful side effects of tyramine.
It’s important to keep in mind how tyramine can affect health. Also, know which foods to cut down on or skip. Talking with a dietitian or a healthcare provider can go a long way in dealing with tyramine issues and boost overall health.
Symptoms might be headaches, migraines, fast heartbeat, and flushing.
Talk with a healthcare pro or dietitian to check your tyramine level. You can do it through personal food tracking or medical checks.
Yes, other pills like selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) may be given for depression or worry if MAOIs don’t work well.
Yes, once you stop using MAOIs, you can slowly bring back high-tyramine foods to your food plan. But remember, always talk to your healthcare pro before making any diet changes.
Yes, coffee typically contains minimal amounts of tyramine. While it is not entirely devoid of tyramine, the levels are generally considered low, making coffee a relatively safe choice for individuals sensitive to this compound.
Tyramine has been associated with triggering heart palpitations in some individuals. High levels of tyramine, particularly in certain foods, may contribute to increased blood pressure, potentially leading to heart palpitations in sensitive individuals.
Potatoes are generally considered low in tyramine, making them a suitable choice for individuals on a low-tyramine diet. However, individual tolerance may vary, and it’s advisable for those with sensitivities to monitor their reactions to specific foods.
Chickpeas are typically low in tyramine, making them a safe choice for individuals following a low-tyramine diet. However, it’s important for individuals with specific sensitivities to monitor their own responses to foods.
Eggs are generally low in tyramine, making them a suitable option for individuals on a low-tyramine diet. However, individual sensitivities may vary, so it’s advisable for those with specific concerns to monitor their reactions to different foods.
Mushrooms are considered moderate to high in tyramine, and individuals sensitive to this compound may want to exercise caution. Monitoring one’s response to mushrooms is advisable for those on a low-tyramine diet or with known sensitivities.
Bananas are generally low in tyramine, making them a safe choice for individuals following a low-tyramine diet. However, individual tolerances may vary, and it’s advisable for those with sensitivities to monitor their own responses to specific foods.
Tomatoes are considered moderate in tyramine content, and individuals sensitive to this compound may need to exercise caution. Monitoring personal reactions is advisable for those on a low-tyramine diet or with specific sensitivities.
Nuts, including almonds and walnuts, are generally considered to have moderate to high tyramine levels. Individuals with sensitivities may need to monitor their intake, especially if following a low-tyramine diet.
Apples are typically low in tyramine, making them a safe choice for individuals on a low-tyramine diet. However, individual sensitivities can vary, and monitoring personal reactions to different foods is advisable.
Popcorn is generally considered low in tyramine, making it a suitable option for individuals on a low-tyramine diet. However, personal sensitivities may vary, and those with specific concerns should monitor their reactions to different foods.
Milk is typically low in tyramine, making it a safe choice for individuals on a low-tyramine diet. However, individual tolerances may vary, and it’s advisable for those with sensitivities to monitor their responses to specific foods.
Broccoli is generally considered low in tyramine, making it a suitable choice for individuals on a low-tyramine diet. However, individual sensitivities may vary, and monitoring personal reactions to different foods is advisable.
Tea, especially black and green tea, is generally low in tyramine, making it a safe choice for individuals on a low-tyramine diet. However, it’s essential to be aware of individual sensitivities and monitor responses to specific foods and beverages.
Yes, chocolate contains tyramine, and for individuals sensitive to this compound, it can potentially trigger adverse effects such as headaches. Monitoring chocolate intake may be advisable for those on a low-tyramine diet or with specific sensitivities.
Peanut butter is generally considered to have moderate to high tyramine levels. Individuals with sensitivities may need to monitor their intake, especially if following a low-tyramine diet.
Yes, tyramine has the potential to increase blood pressure. In individuals sensitive to tyramine or those taking certain medications, consuming high-tyramine foods may lead to a rise in blood pressure, posing a risk of hypertensive crises.
Tyramine typically stays in your system for a few hours, with an elimination half-life of around 20 minutes. However, individual differences and metabolism can affect how long it lingers in the body.
Butter typically contains low levels of tyramine, making it generally safe for consumption for those sensitive to tyramine or on MAOIs. However, individuals with specific concerns should consult with a healthcare professional for personalized advice.
Tyramine intolerance refers to an individual’s sensitivity or inability to properly metabolize tyramine, a compound found in certain foods. Symptoms may include headaches, elevated blood pressure, and other adverse reactions, particularly in those with conditions such as migraines or taking MAOIs.
A low tyramine diet restricts foods high in tyramine, a compound linked to adverse reactions in some individuals, particularly those on MAOIs or with tyramine sensitivity. It typically involves avoiding aged, fermented, and processed foods, opting instead for fresh options like fruits, vegetables, and lean proteins.
Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.
Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.
Comments