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Triglycerides vs Cholesterol: Levels, Differences, and How to Reduce It 

By Dr. Vishesh Bharucha +2 more

Join Health Talk by PharmEasy on WhatsApp

Introduction

There is often a confusion between cholesterol and triglycerides, as both are types of lipids found in the blood. Elevated levels of either can significantly increase the risk of cardiovascular disease (CVD)1.

In 2022, an estimated 19.8 million people died from CVDs worldwide, accounting for approximately 32% of all global deaths, with heart attack and stroke responsible for 85% of these deaths2

triglycerides vs cholesterol

This blog explores what they are, how they differ, their ideal levels, and practical ways to keep them under control. 

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What Are Cholesterol and Triglycerides?

Cholesterol is a waxy, fat-like substance found in all cells of the body3. It plays an important role in building and maintaining cell walls and is needed to make hormones, vitamin D, and bile acids (substances that help to digest food). The liver makes most of the cholesterol the body needs, while the rest comes from foods such as meat, eggs, and dairy products. Although HDL cholesterol (good cholesterol) is essential for good health, too much LDL cholesterol (bad cholesterol) in the blood is a well-established cause of atherosclerotic cardiovascular disease (ASCVD)1,4. HDL participates in reverse cholesterol transport, but this mechanism is more complex than simply removing cholesterol from arteries.

Triglycerides are the most common type of fat in the body and are the body’s main way of storing energy5. After you eat, excess calories that the body does not need right away are converted into triglycerides and stored in fat cells for future energy use. When the body needs energy between meals or during physical activity, these stored triglycerides are broken down and used as fuel. Triglycerides also help keep the body warm and protect organs. However, high triglyceride levels are associated with an increased risk of heart disease. This risk is mainly linked to triglyceride-rich lipoproteins and remnant cholesterol (cholesterol carried in triglyceride-rich fat particles in your blood), rather than triglycerides directly causing the hardening and narrowing of the arteries5,6.

Note: Cholesterol helps build and maintain the body, while triglycerides store and provide energy. Both are necessary for normal functioning of the body; however, keeping their levels within a healthy range is important for protecting the heart. 

Triglycerides vs Cholesterol

The table below explains key details about triglycerides vs cholesterol to help you understand their roles better1,3,5,7:

Feature Cholesterol Triglycerides 
Main Function Helps build cell membranes and is used to produce hormones, vitamin D, and bile acids for digestion Stores excess calories and provides energy when the body needs it. 
Primary Source Produced mainly by the liver  Formed from excess calories consumed through food, especially carbohydrates, fats, and sugars 
How It Travels in Blood Carried by lipoproteins such as low-density lipoprotein (LDL) and high-density lipoprotein (HDL) Transported primarily by chylomicrons and VLDL (very-low-density lipoproteins) 
Normal Range Total cholesterol: <200 mg/dL 
LDL: <100 mg/dL 
HDL: ≥60 mg/dL 
<150 mg/dL 
Health Risk When Elevated High LDL cholesterol can accumulate on the inside of artery walls, increasing the risk of atherosclerosis, heart attack, and stroke High triglyceride levels are associated with an increased risk of ASCVD (due to triglyceride-rich lipoproteins and remnant cholesterol). Very high triglyceride levels (≥500 mg/dL), especially ≥1000 mg/dL, can also greatly increase the risk of acute pancreatitis. 

Diagnosis of Cholesterol and Triglycerides

The most common test used to measure cholesterol and triglycerides is lipid profile (lipid panel). This cholesterol and triglycerides test helps assess cardiovascular health and identify abnormalities in blood lipid levels8.

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Lipid Profile (Lipid Panel)  

1. Purpose

  • Evaluates cholesterol and triglyceride levels in the blood. 
  • Helps assess the risk of CVDs such as heart attack and stroke. 
  • Monitors the effectiveness of lipid-lowering medications8

2. What It Measures

  • Total Cholesterol: The total amount (overall) of cholesterol in the blood. 
  • LDL Cholesterol: Often called bad cholesterol because high levels can lead to plaque buildup in arteries. 
  • HDL Cholesterol: Known as good cholesterol, as it helps carry excess cholesterol away from the arteries and back to the liver. 
  • Triglycerides: The main form of stored fat in the body and an important marker of metabolic and cardiovascular health8.

3. Fasting Requirements 

  • A fasting period of 9 to 12 hours may be recommended before testing8. However, this may not be a routine requirement, so always check with your doctor. 
  • Water can generally be consumed during the fasting period. 

4. When to Get Tested

  • Adults aged 20 years and older should have their cholesterol checked periodically as recommended by their doctor based on individual cardiovascular risk3,7
  • More frequent testing (preferably once a year) may be needed for individuals with3,7
    • High cholesterol or triglycerides 
    • Diabetes 
    • High blood pressure 
    • Obesity 
    • A family history of heart disease 
    • Existing CVDs 

Note: Follow-up testing may be required to monitor response to treatment or lifestyle modifications. 

Foods That Can Help Lower Cholesterol and Triglycerides

Making healthy food choices may help improve cholesterol and triglyceride levels and reduce the risk of heart disease. Foods that can help lower cholesterol and triglyceride levels include9,10

  • Oats and whole grains (oatmeal, oat bran, whole-grain cereals): Contain soluble fibre that reduces the absorption of cholesterol in the gut.  
  • Fruits and vegetables (apples, oranges, pears, bananas, avocados, leafy greens): Provide fibre, vitamins, and antioxidants that support heart health.  
  • Beans, lentils, and chickpeas: Rich in soluble fibre and plant protein, which can help lower cholesterol levels.  
  • Nuts and seeds (almonds, walnuts, flaxseeds, chia seeds): Contain healthy fats, fibre, and omega-3 fatty acids that support healthy cholesterol and triglyceride levels.  
  • Fatty fish (salmon, tuna, sardines): Rich in omega-3 fatty acids, which can help lower triglycerides. However, they may not help reduce cholesterol levels very significantly (and may increase them if taken in large amounts). Therefore, they should be consumed in moderation. 
  • Healthy oils (olive oil and avocado oil): Provide unsaturated fats that can help improve cholesterol levels when used in place of saturated fats. 

Foods that may increase cholesterol or triglyceride levels should be limited. These include: 

  • Foods high in saturated fats, such as fatty cuts of meat, butter, cream, and full-fat dairy products. 
  • Foods containing trans fats, including some fried foods, baked goods, and processed snacks. 
  • Sugary foods and beverages, which can contribute to elevated triglyceride levels9,10.

How to Reduce Cholesterol and Triglycerides Naturally?

Healthy lifestyle changes may help lower cholesterol and triglyceride levels and improve overall heart health. Some options include: 

1. Stay Physically Active 

running
Image Source: Freepik.com
  • Strive for at least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity physical activity each week. 
  • Activities such as brisk walking, swimming, cycling, or jogging can help improve cholesterol levels and lower triglycerides11.
  • Regular aerobic exercise can help lower triglycerides and raise good cholesterol. It usually has a smaller effect on bad cholesterol, but it can still improve overall heart health. 

2. Maintain a Healthy Weight 

weight management
Image Source: Freepik.com
  • Excess body weight is commonly linked to high triglyceride levels, low good cholesterol, and insulin resistance. 
  • Losing even a modest amount of weight (5 to 10% of body weight) can help improve lipid levels and reduce cardiovascular risk10,12.

3. Quit Smoking 

smoking and addiction
Image Source: Freepik.com
  • Smoking damages blood vessels, increases the risk of heart disease, and can negatively affect cholesterol levels. 
  • Stopping smoking is one of the most effective ways to protect your heart and reduce the risk of CVDs. 
  • Seek support from professionals, smoking cessation programs, or nicotine replacement therapies if needed10,11.

4. Limit Alcohol Consumption 

limit alcohol
Image Source: Freepik.com
  • Alcohol adds extra calories and can significantly increase triglyceride levels. 
  • If you choose to drink alcohol, keep your intake moderate10
  • If you have high triglyceride levels, especially very high levels, it is often recommended to avoid alcohol completely because even small amounts can raise triglyceride levels significantly. 

5. Get adequate sleep 

sufficient sleep
Image Source: Freepik.com
  • Aim for 7 to 9 hours of restful sleep each night, as adequate sleep is important for cardiovascular health.  
  • Improve sleep quality by staying physically active during the day, following a regular bedtime routine, and limiting the use of electronic devices before bed12

6. Manage Other Health Conditions 

diabetes
Image Source: Freepik.com
  • Conditions such as diabetes and obesity can affect cholesterol levels by increasing triglycerides and lowering good cholesterol. High blood pressure is also an important risk factor for heart disease, but it does not directly affect cholesterol levels to the same extent1,3,5
  • Regular health check-ups and following your doctor’s advice can help keep these conditions under control. 

Also Read: High LDL (Bad) Cholesterol: Causes, Symptoms & How to Reduce It 

When to Consult a Doctor?

While mild changes in cholesterol and triglyceride levels can often be managed through lifestyle modifications, it is important to consult a doctor if you have concerns about your heart health or lipid levels. 

You should seek medical advice if: 

  • Your lipid profile shows high cholesterol or triglyceride levels. 
  • You have a family history of high cholesterol, high triglycerides, or CVDs. 
  • You have risk factors such as diabetes, high blood pressure, obesity, or smoking3,5,8.
  • You experience symptoms that may indicate CVDs, such as2
    • Chest pain or discomfort 
    • Shortness of breath 
    • Dizziness or unexplained fatigue 
    • Pain/numbness/weakness in the arms or legs 
  • Lifestyle changes have not improved your cholesterol or triglyceride levels. 
  • You are taking cholesterol-lowering medication and need regular follow-up tests to monitor your lipid levels. 

Also Read: Low HDL (Good) Cholesterol: Causes, Symptoms & How to Increase It

Conclusion

Cholesterol and triglycerides are both essential fats that play important roles in the body; however, elevated levels of both can increase the risk of heart disease, heart attack, and stroke. Therefore, understanding the differences between cholesterol and triglycerides, knowing the levels of both, and getting regular lipid profile tests can help you stay on top of your cardiovascular health.  

Healthy lifestyle habits (such as eating a balanced diet, staying physically active, maintaining a healthy weight, avoiding smoking, and limiting alcohol intake) can go a long way in improving cholesterol and triglyceride levels and reducing the risk of heart conditions.  

Frequently Asked Questions (FAQs)

Which is worse, cholesterol or triglycerides? 

Neither is necessarily ‘worse’ than the other. Both may increase the risk of CVDs when their levels are elevated. High LDL (bad) cholesterol is a well-established risk factor for atherosclerosis, while high triglycerides are also linked to heart disease and often occur alongside conditions such as obesity or diabetes3,5. However, your overall cardiovascular risk is determined by your complete lipid profile and other health conditions. 

Why are my triglycerides high but not my cholesterol? 

High triglycerides may occur even when cholesterol levels are normal. Common causes include consuming excess calories, diets high in sugar or refined carbohydrates, obesity, physical inactivity, excessive alcohol intake, uncontrolled diabetes, and certain medications5. Consulting a doctor can help identify the reason for elevated triglyceride levels and guide appropriate management. 

What is the relationship between cholesterol and triglycerides?

Cholesterol and triglycerides are both lipids (serving different functions) that circulate in the bloodstream. Cholesterol helps build cells and produce hormones, while triglycerides store energy1.1 Both are measured in the lipid profile test8

Can high triglycerides and cholesterol cause fatigue? 

High cholesterol and triglycerides usually do not cause noticeable symptoms, including fatigue. However, they can contribute to CVDs that may result in fatigue, shortness of breath, or difficulty performing physical activities13. If you experience persistent fatigue, you should consult a doctor for further evaluation. 

Can triglycerides cause high cholesterol?

Triglycerides do not directly cause high cholesterol. However, both can be elevated due to similar factors such as an unhealthy diet, obesity, lack of physical activity, diabetes, or genetic conditions. As a result, high triglycerides and high cholesterol often occur together3,5

Can stress raise cholesterol and triglycerides? 

Long-term stress may contribute to higher cholesterol and triglyceride levels. Stress triggers the release of hormones, which may affect how the body processes fats and can lead to increased triglyceride levels14. In addition, stress may lead to unhealthy lifestyle habits such as overeating, smoking, excessive alcohol consumption, and physical inactivity, which could contribute to elevated cholesterol and triglyceride levels12.  

References

1. Cox RA, García-Palmieri MR. Cholesterol, Triglycerides, and Associated Lipoproteins. In: Walker HK, Hall WD, Hurst JW, eds. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd ed. Butterworths; 1990. Accessed June 2, 2026. http://www.ncbi.nlm.nih.gov/books/NBK351/ 

2. Cardiovascular diseases (CVDs). Accessed June 2, 2026. https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds) 

3. Cholesterol. Accessed June 2, 2026. https://medlineplus.gov/cholesterol.html 

4. Huff T, Boyd B, Jialal I. Physiology, Cholesterol. In: StatPearls. StatPearls Publishing; 2026. Accessed June 2, 2026. http://www.ncbi.nlm.nih.gov/books/NBK470561/ 

5. Triglycerides. Accessed June 2, 2026. https://medlineplus.gov/triglycerides.html 

6. Services D of H& H. Triglycerides. Accessed June 2, 2026. http://www.betterhealth.vic.gov.au/health/conditionsandtreatments/triglycerides 

7. Cholesterol Levels: What You Need to Know. Accessed June 2, 2026. https://medlineplus.gov/cholesterollevelswhatyouneedtoknow.html 

8. Lipid profile test: MedlinePlus Medical Encyclopedia. Accessed June 2, 2026. https://medlineplus.gov/ency/article/007812.htm 

9. How to Lower Cholesterol with Diet. Accessed June 2, 2026. https://medlineplus.gov/howtolowercholesterolwithdiet.html 

10. Services D of H& H. Cholesterol – healthy eating tips. Accessed June 2, 2026. http://www.betterhealth.vic.gov.au/health/conditionsandtreatments/cholesterol-healthy-eating-tips 

11. High cholesterol – How to lower your cholesterol. nhs.uk. May 28, 2019. Accessed June 2, 2026. https://www.nhs.uk/conditions/high-cholesterol/how-to-lower-your-cholesterol/ 

12. Jan 2 LR, 2025. Lifestyle Changes to Prevent a Heart Attack. www.heart.org. Accessed June 2, 2026. https://www.heart.org/en/health-topics/heart-attack/life-after-a-heart-attack/lifestyle-changes-for-heart-attack-prevention 

13. Khan MR, Haider ZM, Hussain J, Malik FH, Talib I, Abdullah S. Comprehensive Analysis of Cardiovascular Diseases: Symptoms, Diagnosis, and AI Innovations. Bioengineering. 2024;11(12):1239. doi:10.3390/bioengineering11121239 https://pubmed.ncbi.nlm.nih.gov/39768057/

14. Anni NS, Jung SJ, Shim JS, Jeon YW, Lee GB, Kim HC. Stressful life events and serum triglyceride levels: the Cardiovascular and Metabolic Diseases Etiology Research Center cohort in Korea. Epidemiol Health. 2021;43:e2021042. doi:10.4178/epih.e2021042 https://pubmed.ncbi.nlm.nih.gov/34126706/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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