Khadiradi Vati: Uses, Benefits, Side Effects & More

Introduction

Khadiradi Vati is an ayurvedic formulation made from multiple herbs. Khadira (Acacia catechu) is the major ingredient in the formulation, along with Bhimseni kapoor (Cinnamomum camphora), Kankol (Piper cubeba), Supari (Areca nut), and Javitri (Myristica fragrans)¹. The main ingredient Khadira is responsible for most of its therapeutic benefits. Acacia catechu is an important medicinal plant and an economically significant forest tree².  

There are various phytochemicals present in Khadiradi Vati like flavonoids, glycosides, saponins, tannins, alkaloids, and volatile oils¹. 

Nutritional Value of Khadiradi Vati

Phytochemical screening of Khadiradi Vati shows the presence of carbohydrates and proteins aside from phytochemicals¹. 

Potential Uses of Khadiradi Vati

Khadiradi Vati is used for pharyngitis (sore throat), mouth ulcers, and other diseases of teeth, gums, tongue, and sore throat¹. It has the following activities that make it a potentially beneficial medicinal formulation:  

• antiseptic¹  
• astringent¹  
• anti-inflammatory¹ 
• expectorant¹ 

The major ingredient of Khadiradi Vati, Acacia catechu, is helpful in cough, eruptions on the body and ulcers².

Benefits of Khadiradi Vati

Khadiradi Vati is beneficial in sore throat, tonsillitis, and pharyngitis.  

1. Benefit of Khadiradi Vati in Oral Health

As per the Ayurvedic Formulary of India¹¹, Khaidradi Vati is useful in Mukha daurgandhya (Halitosis), Mukha Paka (Stomatitis), Danta Roga (Disease of the tooth), Dantasausirya (Dental caries), Gala Roga (Diseases of the throat), Aruci (Tastelessness), Caladanta (Loose tooth), Mukhajadya (Restricted movement of the jaw), and Asya Roga (Diseases of the buccal cavity)³ and cough with expectoration⁴. 

2. Benefit of Khadiradi Vati for Gum Diseases

• The chief ingredient of Khadiradi Vati, Acacia catechu, is an excellent antimicrobial and anti-inflammatory agent.
• It increases the concentration of vitamin C in the cells, along with the elimination of free radicals.
• It inhibits collagen destruction.
• These effects of Khadiradi Vati help in relieving periodontitis.
• Khadiradi vati was found to be superior to chlorhexidine and comparable to Dashansanskar churana in the treatment of chronic periodontitis⁵.  

Over the years, I have learned that Khadiradi Vati, along with other Ayurvedic medicines, may potentially provide relief in cases of Lichen Planus. Khadiradi Vati is known for its anti-inflammatory and immunomodulatory properties, which can help alleviate the symptoms associated with Lichen Planus, such as skin lesions and itching¹⁰.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Also Read: Nirgundi: Benefits, Uses, Side Effects & More! 

3. Benefit of Khadiradi Vati for Mouth Sores

• Mukhapaka or stomatitis is a commonly occurring disease of the oral cavity.
• It can affect the gums, lips, palate and inside of the cheeks.
• Khadiradi Vati can help relieve symptoms of stomatitis ulcers as it has anti-inflammatory, antiseptic and astringent properties.
• Khadiradi Vati was found to be highly effective in the management of Mukhpak (stomatitis) in studies⁶. 

4. Benefit of Khadiradi Vati in Sore Throat

• Pharyngitis or sore throat is a disorder that affects adults as well as children.
• Chronic pharyngitis is the inflammation of the food pipe in the throat region for an extended period of time.
• Ayurvedic treatment with Khadiradi vati might be effective alternative management of chronic pharyngitis when combined with a proper diet and regimen⁷.  

5. Benefit of Khadiradi Vati in Cough with Sputum

As per the National Health Portal of India, sucking on Khadiradi Vati might be beneficial in cough with bringing up and spitting out sputum⁴. 

I would advise considering the use of Khadiradi Vati, an Ayurvedic herbal formulation that contains Acacia as a major ingredient, for its potential hepatoprotective activity. Acacia is believed to possess properties that can protect the liver from damage and promote its well-being⁹.

Dr. Rajeev Singh, BAMS

How to Use Khadiradi Vati?

Khadiradi Vati is available as pills.  

The dose of khadiradi Vati pills, to be sucked or swallowed, with water or honey⁸ should be decided by a qualified ayurvedic doctor. The ayurvedic doctor will prescribe you the dose, based on your diagnosis.   

Also Read: Sesame Seeds: Benefits, Uses, Side Effects and More!

Side Effects of Khadiradi Vati

Khadiradi Vati has no reported side effects⁵.  

Precautions to Take with Khadiradi Vati

• There are no safety studies about its usage in pregnant and breastfeeding women. Therefore, it should be used with the doctor’s advice and supervision.   
• There are no safety studies about its usage in children.  

Also Read: Sarpagandha (Indian Snakeroot): Uses, Benefits, Side Effects, Precautions & More!

Conclusion

Khadiradi Vati is a trusted Ayurvedic polyherbal formulation with a wide range of benefits for oral and respiratory health. Its antiseptic, anti-inflammatory, astringent, and expectorant properties make it effective in managing conditions like periodontitis, stomatitis, sore throat, and cough. With no reported side effects and recognition in the Ayurvedic Formulary of India, it remains a reliable traditional remedy. However, it is always advisable to consult a qualified Ayurvedic doctor before use, particularly for pregnant women, breastfeeding mothers, and children.

Also Read: Chironji (Charoli): Uses, Benefits, Precautions, Side Effects & More!

Frequently Asked Questions (FAQs)

References

1. BP A, MC R, SM P, Murthy Dr N. Formulation and standardization of khadiradi vati and comparative study with marketed formulation. Journal of Pharmacognosy and Phytochemistry [Internet]. 2019 [cited 2022 Feb 18];8(3):2299–301. Available from: https://www.phytojournal.com/archives/2019.v8.i3.8353/formulation-and-standardization-of-khadiradi-vati-and-comparative-study-with-marketed-formulation 

2. Negi BS, Dave BP. In Vitro Antimicrobial Activity of Acacia catechu and Its Phytochemical Analysis. Indian Journal of Microbiology 2011 50:4 [Internet]. 2011 Feb 2 [cited 2022 Feb 18];50(4):369–74. Available from: https://link.springer.com/article/10.1007/s12088-011-0061-1 

3. Pharmacopoeia Commission For Indian Medicine & Homoeopathy. The Ayurvedic Pharmacopoeia Of India Part-I Volume-Ix Government Of India Ministry Of Ayush 2016. 2016.  https://www.ayurveda.hu/api/API-Vol-1.pdf

4. Ardra-Kasa(Cough with expectoration) | National Health Portal of India [Internet]. [cited 2022 Feb 18]. Available from: https://jaims.in/jaims/article/view/4207 

5. Mittal N, Joshi V, Srivastava R, Singh S. Efficacy of Ayurvedic drugs as compared to chlorhexidine in management of chronic periodontitis: A randomized controlled clinical study. Journal of Indian Society of Periodontology [Internet]. 2018 Jan 1 [cited 2022 Feb 18];22(1):28. Available from: https://pubmed.ncbi.nlm.nih.gov/29568169/

6. Deshmukh R D, Dhakate VG, Pawar N S, Ingle A M, Barde R R. A CLINICAL CASE STUDY-ROLE OF TRIPHALA CHURNA PRATISARANA AND KHADIRADI VATI IN THE MANAGMENT OF MUKHAPAKA WITH SPECIAL REFERENCE TO STOMATITIS. Deshmukh et al World Journal of Pharmaceutical Research [Internet]. 2020;9:1201. https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1599122413.pdf

7. N V Vidya BEVD. Ayurveda Treatment Protocol in the Management of Galagraha (Pharyngitis)-A Case Study. Journal of Ayurvedic and Herbal Medicine [Internet]. 2020;6(2):63–5. Available from:  https://www.researchgate.net/publication/352410387_Ayurveda_Treatment_Protocol_in_the_Management_of_Galagraha_Pharyngitis-A_Case_Study

8. Department of Ayush M of H and FWG of I. Essential Drugs List(EDL)_Ayurveda. http://namayush.gov.in/sites/all/themes/webcms/images/essential_drugs/Ayurveda_EDL_list_final.pdf

9. Lakshmi T, Sri Renukadevi B, Senthilkumar S, Haribalan P, Parameshwari R, Vijayaraghavan R, Rajeshkumar S. Seed and bark extracts of Acacia catechu protects liver from acetaminophen induced hepatotoxicity by modulating oxidative stress, antioxidant enzymes and liver function enzymes in Wistar rat model. Biomed Pharmacother. 2018;108:838-844. doi:10.1016/j.biopha.2018.08.077. https://www.sciencedirect.com/science/article/pii/S0753332218345773

10. Srinivas T, Rashmika K, Rani GS, Rao SB, Laxmi V. A critical review on Khadiradi Vati – an Ayurvedic formulation. J Ayurveda Integr Med Sci. 2024;9(8):146-156. doi:10.21760/jaims.9.8.22. https://jaims.in/index.php/jaims/article/view/3737

11. India. Ayurvedic Pharmacopoeia Committee. The Ayurvedic Formulary of India. 2nd rev ed. New Delhi: Controller of Publications; 2003 https://openlibrary.org/works/OL6053604W/The_Ayurvedic_formulary_of_India

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