PharmEasy Blog

Ajwain: Uses, Benefits, Side Effects, and More!

Introduction

Ajwain (Carum copticum), also called bishop’s weed, is a herb that is used as a spice and a major ingredient in different types of medicines. It is thought to have originated in Egypt and the eastern Mediterranean region. Ajwain is extensively cultivated in black soil, especially along the riverbanks in Egypt and several other countries like Iran, Afghanistan, and India. The seeds are small yet have a hot, pungent, and bitter taste. Ajwain functions as a stomachic (helping promote appetite or helping in digestion) and laxative, and is used as an appetiser. It may be helpful for conditions like piles, abdominal tumours, abdominal pain, vomiting, mouth diseases, etc1.

Nutritional Value of Ajwain

The major constituent of ajwain is an essential oil called thymol, which constitutes about 35-60%. The seed also contains compounds like β-pinene, para-cymene, α-pinene, limonene, and γ- and β-terpinenes3. Ajwain seeds also comprise protein, fat, fibre, minerals, calcium, iron, phosphorus, carotene, riboflavin, niacin, thiamin, and carbohydrates. In 100 grams of ajwain, the nutrients found are1,2:

Properties of Ajwain

Ajwain is known to have many properties like3:

Potential Uses of Ajwain

1. Potential uses of ajwain for digestion

Ajwain may help reduce irregular intestinal and stomach pain in both adults and children. Taking ajwain with common salt and warm water may relieve colicky pain (sharp intestinal pain) caused by gas, indigestion, or intestinal infections. It can also be taken with buttermilk to ease digestion-related issues1. Consult your doctor before taking it for any condition.

2. Potential uses of ajwain for respiratory problems

A mixture of ajwain and ginger may be prescribed by your doctor in cases of chronic bronchitis and asthma. This mixture might help expel mucus and may improve the symptoms of chronic bronchitis and asthma. It may also be helpful for chronic colds and coughs. Consuming warm water after chewing ajwain might help reduce a cough. Chewing betel leaf with ajwain might help with a dry cough1. It is, however, essential to consult your doctor before taking it for these conditions.

3. Potential uses of ajwain for diabetes

Ajwain seeds may be helpful for diabetes4. Powdered neem leaves can be taken with warm milk along with powdered ajwain and cumin seeds. This combination might help reduce blood sugar levels. However, it’s essential to consult your doctor before taking this. Moreover, a condition like diabetes must be diagnosed and treated by a doctor.

4. Potential uses of ajwain for migraine

Smelling ajwain seeds wrapped in a tissue may help in dealing with migraines3. Ajwain seeds can also be burned, and the fumes inhaled, to address other head-related issues1. However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using ajwain for any apparent health benefits.

5. Potential uses of ajwain for arthritis

Ajwain seed oil may be helpful for pain related to arthritis3. This oil can be used regularly for massage on the affected joints to alleviate pain in rheumatic arthritis1. Kindly consult a doctor before using it.

6. Potential uses of ajwain for diarrhoea

Consuming ajwain seeds might be a natural way to help deal with diarrhoea or dysentery5. A handful of ajwain seeds can be boiled and added to a glass of water. This mixture can be cooled and consumed to help with diarrhoea. However, such effects need to be ascertained by further research.

Other Potential uses of ajwain

Ajwain seeds might also be used as an insecticide6. Moreover, they may also be used for poisonous insect bites.

Although studies showing the potential uses of ajwain in various conditions are limited, there is a need for further research to establish the true extent of ajwain’s benefits on human health. 

Also Read: Black Chana: Uses, Benefits, Side Effects By Dr. Rajeev Singh

How to Use Ajwain?

Ajwain seeds might be used as it is or they can be used in powder form. Your ayurvedic doctor will prescribe you the correct form and dosage for use for your condition. Kindly refer to your doctor for advice

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Also Read: Black Salt: Uses, Benefits, Side Effects, Precautions & More!

Side Effects of Ajwain

When consumed in moderation, ajwain seeds do not produce any harmful side effects. However, in people suffering from conditions like diverticulitis (pain and inflammation in small, bulging pouches that can form in the lining of the digestive tract), ulcerative colitis (inflammatory bowel disease), and liver diseases, excess intake of ajwain might lead to some side effects.

Precautions to Take with Ajwain

It is important to keep these points in mind when using ajwain seeds:

Also Read: Brahmi: Uses, Benefits, Side Effects, and more!

Interactions with Other Medicines

Ajwain might interact with unknown medicines. Therefore, you should consult a doctor before using ajwain for its potential health benefits.  

Frequently Asked Questions (FAQs)

What are the other names of ajwain?

The common names of ajwain include ajwain, jevain, oma, omam, yom, omu, vamu, yamini, oman, jain, yaminiki, yavan, and more9.

Can ajwain be used for dental problems?

Ajwain seeds might be helpful for tooth pain. Using clove oil, ajwain oil, and water might help to deal with toothache, tooth decay, and bad mouth odour. It may help maintain oral hygiene. However, please consult a dentist for dental problems and do not self-medicate.

Can ajwain be used for skin-related problems?

A paste can be prepared from ajwain seeds and may be applied on any affected part of the face or body to help with itching, boils, and eczema (a condition in which patches of skin become inflamed, itchy, cracked, and rough). In case of acne, powdered ajwain seeds might be taken with yoghurt and applied to the face. This remedy may help manage acne scars. However, more research is required to prove these effects.

Can ajwain be used to treat piles?

Consuming buttermilk with ajwain seeds and rock salt might help reduce the bleeding in piles9. However, please consult a doctor before using such a remedy.

References

  1. Rashmi Yadav, Chandan Kumar Pradhan, Deepika Gupta, Rahul Kaoshik; Health benefits of Indian aromatic plant ajwain (Tachychpermum Ammi). International Jounral of pharmacy and technology. 2011 3(3): 1356-1366. Available from: https://www.researchgate.net/publication/317041607_Health_benefits_of_Indian_aromatic_plant_Ajwain_Trachycpermum_ammi/link/592d01d50f7e9b9979b38e9c/download
  2. U.S Department of agriculture. Ajwain seed whole organic spices. [Internet] Available from: https://fdc.nal.usda.gov/fdc-app.html#/food-details/806341/nutrients
  3. Rajeshwari CU, Kumar AVV, Andallu B. Therapeutic Potential of Ajwain (Tracyspermum ammi L.) Seeds. Elsevier eBooks. 2011 [cited 2025 Apr 29]. Available from: https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/ajwain 
  4. Zarshenas MM, Moein M, Samani SM, Petramfar P. An Overview on Ajwain (Trachyspermum ammi) Pharmacological Effects; Modern and Traditional. Journal of Natural Remedies. 2013 [cited 2025 Apr 29]. Available from: https://www.researchgate.net/publication/262001210_An_Overview_on_Ajwain_Trachyspermum_ammi_Pharmacological_Effects_Modern_and_Traditional 
  5. Boskabady MH, Alitaneh S, Alavinezhad A. Carum copticum L.: A Herbal Medicine with Various Pharmacological Effects. BioMed Research International. 2014 [cited 2025 Apr 29]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4096002/ 
  6. Singla N. Chemistry and insecticidal activity of ajwain seed essential oil against rice weevil. ResearchGate. 2017 [cited 2025 Apr 29]. Available from: https://www.researchgate.net/publication/332383531_Chemistry_and_insecticidal_activity_of_ajwain_seed_essential_oil_against_rice_weevil 
  7. Mofleh IAA. Spices, herbal xenobiotics and the stomach: Friends or foes? World Journal of Gastroenterology. 2010 [cited 2025 Apr 29]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC2883126/ 
  8. Mohapatra S. An overview on Ajwain (Carom Seed) against COVID-19. www.alliedacademies.org. [cited 2025 Apr 29]. Available from: https://doi.org/10.35841/aaagim-7.5.192 
  9. Admin. Ethnobotanical, phytochemical and pharmacological science of Trachyspermum ammi (Ajwain): A systematic review. International Journal of Pharmaceutical Sciences and Research (IJPSR). 2021 [cited 2025 Apr 29]. Available from: https://ijpsr.com/bft-article/ethnobotanical-phytochemical-and-pharmacological-science-of-trachyspermum-ammi-ajwain-a-systematic-review/  

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Olive Oil: Uses, Benefits, Side Effects and More!

Introduction

Olive (Olea europaea L.) is a small tree native to tropical and mildly temperate regions of the world that belongs to the Oleaceae family. The tree, famous for the olive, is commercially important in the Mediterranean region as a primary supplier of olive oil1

The olive tree has long been used for possible medical and nutritional purposes. Olive leaf extracts might have been used to promote health. The high content of fatty acids and functional bioactive compounds such as tocopherols, carotenoids, phospholipids, and phenolics with diverse biological activities are primarily responsible for olive oil’s potential health benefits. These components also contribute to the distinct flavour and taste of olive oil. Similarly, they have been revered as a well-known folk remedy for fever and some tropical disorders such as malaria. Due to their bitterness, olives are rarely utilised in their natural form; nevertheless, they are ingested in one of two forms: oil or table olives1.

The olive oil is obtained from olives (the fruits of Olea europaea L. tree). It is a chief constituent of the Mediterranean diet and is currently gaining popularity as a component of a healthy diet among consumers in northern Europe, the USA, Canada, and other nations. Olive oil is produced almost entirely in Spain, Italy, Greece, Tunisia, Turkey, Morocco, and Portugal2.

Virgin olive oil is produced by mechanical procedures. Ordinary virgin olive oil, fine virgin olive oil, and extra virgin olive oil are the three edible grades of virgin olive oil2. Extra virgin olive oil comprises two chemical compounds: triglycerides (97 to 99 %) and minor components (1 to 3 %)3.

Did you know?

Nutritional Value of Olive Oil

The nutritional content of 100 g of olive oil is4:

Properties of Olive Oil

Various properties of olive oil are listed below.

Potential Uses of Olive Oil

1. Potential Use of Olive Oil for Infections

infections

Oleuropein, a phytoconstituent in olive, has antibacterial properties against bacteria, including mycoplasma. Furthermore, the phenolic chemicals in olive oil might degrade bacterial membranes, hence showing antibacterial actions. Several authors also claim that oleuropein might act against toxins produced by Staphylococcus aureus and might have an antiviral effect against herpes and hepatitis viruses. Oleuropein might also have an antiviral impact against the parainfluenza virus. Furthermore, the potential antiviral activity of olive leaf extract against the virus that causes acquired immunodeficiency syndrome has been proposed3.

The polyphenolic content of olive extract may be linked to a notable antibacterial action. Malaria infections may have been curbed with oral dosages of olive leaves. Studies have proven polyphenols may inhibit the development and reproduction of Bacillus cereus, Klebsiella pneumonia, Salmonella typhi and Escherichia coli. Olive oil has been demonstrated to have potential antibacterial properties for intestinal and respiratory infections5. However, its use needs to be confirmed by further research.

2. Potential Use of Olive Oil for the Liver

liver

Olive oil has long been the main ingredient of the Mediterranean diet. Oleic acid and polyphenols have been shown to protect the liver in various animal studies and cell culture studies. These olive oil components have also been demonstrated to be helpful for different hepatic diseases, such as liver ballooning (increased liver size) and liver steatosis (fat accumulation in the liver), and might aid against drug-induced liver damage5.

Through the potential antioxidant effect of its polyphenolic contents, extra virgin olive oil might decrease inflammation, may reduce the risk of liver damage, and might slow the advancement of steatohepatitis (fat deposition in the liver). Researchers found that consuming extra virgin olive oil might reduce liver tissue damage in animal models. Furthermore, the combined therapy of olive oil and camel milk in animal models demonstrated possible liver protective effects in drug-induced liver toxicity due to their potent antioxidant action5. However, liver diseases can be serious and need proper diagnosis and treatment by a professional.

3. Potential Use of Olive Oil for Cancer

cancer

Olive oil’s phenolic antioxidants might help against the damaging effects of free radicals and the consequent alterations in cellular structures. Scientists investigated the impact of olive oil on colon cancer. Their findings suggested that the presence of antioxidants, phenolic compounds, and fatty acids in olive oil might play an essential role in lowering the risk of colon cancer3.

Studies have investigated the effect of hydroxytyrosol (antioxidant present in virgin olive oil) on cancer cell growth, apoptosis (cell death), and cell cycle. The findings support that hydroxytyrosol might help against cancer and may help trigger cancer cell death and stop the cell cycle. Olive oil contains vitamin E, which might protect the skin from the sun. As a result, it might help against premature ageing and skin cancer3. However, cancer is a serious disease and must be diagnosed and treated by a doctor.

Studies8 say that extra virgin olive oil may help people living with rheumatoid arthritis. Extra virgin olive oil is known to be beneficial due to its anti-inflammatory properties. The long-term, progressive, multi-step, and complicated process of rheumatoid arthritis causes inflammation in a number of joints, causing severe swelling and stiffness in the joints as well as bone and cartilage degradation and joint degeneration and the use of this oil may help ease the inflammation and stiffness.

Dr. Rajeev Singh, BAMS

4. Potential Use of Olive Oil for the Kidney

kidney health

As dietary virgin olive oil and olive leaf extract might help protect kidneys from damage in animal models, it is well known that virgin olive oil is helpful against the progression of kidney damage generated by various chemical agents. It was found that a combination of olive oil and naringenin containing drugs might curb kidney damage in rats by potentially increasing renal function and lowering serum urea and creatinine concentrations5.

Another study5 found that extra virgin olive oil might help reduce the chances of kidney damage in drug-exposed animal models while also improving the antioxidant and health status of the animals. Furthermore, the administration of extra virgin olive oil significantly lowered inflammatory markers, uric acid, creatinine, and urea levels in the serum of an animal model. According to studies, the control of kidney damage by olive oil consumption was due to its phenolic components, which acted as potent lipid peroxidation inhibitors.

5. Potential Use of Olive Oil for Wounds

wound healing

Olive oil can act as a barrier between open wounds and the surroundings. Furthermore, olive oil might speed up wound healing by sterilising the wound surface and helping fight against infections3. However, the effects of olive oil need more scientific backup in the form of research.     

6. Potential Use of Olive Oil for the Heart

heart

Olive oil might have the following actions like increasing high-density lipoprotein, decreasing low-density lipoprotein, reducing cholesterol and triglycerides, and decreasing cholesterol to high-density lipoprotein ratio3.

Nearly two-thirds of people with diabetes die as a result of heart disease. One of the significant risk factors for heart disease in diabetics is increased blood glucose and lipids levels. According to scientists, replacing solid vegetable oil with olive oil in the diet of diabetic patients might be more efficient than sunflower oil against heart diseases due to the favourable effect of olive oil on blood glucose and lipid parameters3. Their use for this purposes is not yet confirmed. Moreover, you should always consult a doctor for serious conditions such as heart diseases.

7. Potential Use of Olive Oil for the Brain

brain

Olive oil constituents like fatty acid and polyphenols may be absorbed through the gastrointestinal tract, and some penetrate specific brain areas. Polyphenols and vitamin E have considerable antioxidant effects on accumulated free radicals in the brain, neutralising them in the case of ischaemia (inadequate blood supply to an organ or tissue)3.

Ischaemia, hypoxia (low oxygen level), and free radicals can harm the brain. Consumption of olive oil following ischaemia can reduce brain cell death and protect the brain from toxic substances. According to the findings of one study, pre-treatment with virgin olive oil resulted in reduced levels of cell death and, as a result, lower levels of stroke in the studied animal model. This was most likely due to changes in the brain lipid composition3.

Olive oil might have a favorable effect on Parkinson’s disease (brain disorder) because the polyphenols in olive oil which can affect a cellular mechanism involved in the disease’s development and progression. According to laboratory experiments, oleuropein (a component of olive oil) might have the potential to diminish cell damage, apoptosis (cell death), and oxidative stress, suggesting the brain-protective effect of oleuropein5.

8. Potential Use of Olive Oil for Intestines

stomach

A protective effect of extra virgin olive oil’s polyphenols against ulcerative colitis (inflammatory bowel disease) progression has been studied. The extract of olive oil polyphenols was able to inhibit the production of hydrogen peroxide and nitric oxide triggered by oxysterols (a by-product of cholesterol synthesis) and preserve cellular antioxidant levels in the intestines. Furthermore, olive oil’s phenols may have blocked the key inflammatory processes driven by oxysterols6. However, more research is required to prove these claims and potential benefits of olive oil for human health.

Though there are studies that show the potential uses of olive oil in various conditions, but these are insufficient and there is a need of further studies to establish the true extent of benefits of olive oil on human health. 

From my knowledge, the components of extra virgin olive oil may help preserve the neurological system and may be helpful against sadness and anxiety, according to a 2013 research done on mice. Researchers recently discovered that people who ingested trans-fats, an unhealthy lipid prevalent in fast food and pre-packaged baked products, were more likely to experience sadness than persons who consumed unsaturated fats like olive oil9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Olive Oil?

Olive oil can be used as:

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Also Read: Castor Oil – Uses, Benefits, Precautions & More!

Side Effects of Olive Oil

There are no major side effects of olive oil reported by far. If you experience any side effects, seek immediate medical help from your doctor who has prescribed it to you. They will be the best guide for providing proper treatment to overcome side effects.

Precautions to Take with Olive Oil

The safety studies of olive oil on pregnant and breastfeeding women have not been documented. Likewise, there is no information available on the safety studies of olive oil in children. Therefore, it should only be taken under the supervision and advice of a physician.

Also Read: 6 Simple Health Benefits of Essential Oils!

Interactions with Other Drugs

There is not much information available on how olive oil interacts with other medications. Hence, patients should consult a doctor before taking olive oil if they take any other drug or supplement.

Also Read: Sunflower Oil: Uses, Benefits, Side Effects By Dr. Rajeev Singh

Frequently Asked Questions (FAQs)

What is olive oil?

It is an oil obtained from the Olea europaea L. tree fruits2.

Is olive oil good for hair?

Olive oil might be good for hair. According to a study6, the carotenoids in olive oil helps in treating the internal region (cortex) of the hair fibre, hence it might help strengthen hair. However, concrete evidence is needed in the form of more research.

Is olive oil good for the face?

Olive oil might be good for the face. The concomitant use of other oils such as buckthorn oil with olive oil might have positive effects on the skin7.

Is olive oil good for health?

Olive oil might have positive effects on health. The high content of fatty acids and functional bioactive compounds such as tocopherols, carotenoids, phospholipids, and phenolics with diverse biological activities are primarily responsible for olive oil’s potential health benefits. However, more research is required to ascertain these claims.

What are the types of olive oil?

Olive oil is of various types: virgin olive oil (edible), extra virgin olive oil (edible), refined olive oil (edible), olive-pomace oils (non-edible) and lampante olive oil (non-edible)4.

What is the use of olive oil?

It is a principal constituent of the Mediterranean diet2. Apart from its nutritional value, it might have potential use for its potential antioxidant, anti-inflammatory, anti-microbial, anti-tumour, anti-platelet aggregation, blood pressure-lowering, immunity enhancing, anti-allergic, hypolipidemic, wound healing, kidney-protective, heart-protective, liver-protective and brain-protective activities. However, more research is required to prove these possible effects of olive oil on human health.

Can olive oil be used for cooking?

Olive oil is used for cooking. It is commonly used in food preparations such as salad oil, cooking oil, frying and pasta sauces1.

Can extra virgin olive oil be used for cooking?

Yes, extra virgin olive oil is used for cooking. Extra virgin olive oil, fine virgin olive oil, and ordinary virgin olive oil are the three edible grades of virgin olive oil2.

Is olive oil good for cholesterol?

Olive oil might help lower blood cholesterol levels. Consuming olive oil might lead to a reduction in cholesterol levels3. However, more research is required to prove these effects.

Is olive oil good for ulcerative colitis?

Yes, olive oil might be helpful for ulcerative colitis. The polyphenols of the extract of olive oil might inhibit the production of hydrogen peroxide and nitric oxide and might preserve cellular antioxidant levels in the intestine6. However, more research is needed to ascertain such claims.

References

  1. Ghanbari R, Anwar F, Alkharfy KM, Gilani AH, Saari N. Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)-a review. Int J Mol Sci. 2012; 13(3): 3291-3340. Available from: https://pubmed.ncbi.nlm.nih.gov/22489153/
  2. Tsimidou M, Blekas G, Boskou D. OLIVE OIL. In: Encyclopedia of Food Sciences and Nutrition (2nd ed). Elsevier Science Ltd; 2003:4252–4260. doi:10.1016/B0-12-227055-X/01347-X. Available from: https://www.sciencedirect.com/science/chapter/referencework/abs/pii/B012227055X01347X
  3. Yousefi Z, Rezaeigolestani M, Hashemi M. Biological Properties of Olive Oil. J Hum Environ Health Promot. 2018; 4(2): 50-54. Available from: https://oaji.net/articles/2019/4672-1562994176.pdf
  4. Bilal R, Liu C, Zhao H, Wang Y, Farag M, Alagawany M et al. Olive Oil: Nutritional Applications, Beneficial Health Aspects and its Prospective Application in Poultry Production. Frontiers in Pharmacology. 2021;12. Available from: https://fdc.nal.usda.gov/fdc-app.html#/food-details/748608/nutrients
  5. Bilal RM, Liu C, Zhao H, Wang Y, Farag MR, Alagawany M, et al. Olive oil: nutritional applications, beneficial health aspects and its prospective application in poultry production. Front Pharmacol. 2021;12. Available from: https://www.frontiersin.org/articles/10.3389/fphar.2021.723040/full
  6. Leite MG, Campos PM. Development and efficacy evaluation of hair care formulations containing vegetable oils and silicone. Int J Phytocosmet Nat Ingre. 2018; 5(1):9. Available from: https://www.researchgate.net/publication/332582347_Development_and_efficacy_evaluation_of_hair_care_formulations_containing_vegetable_oils_and_silicone
  7. Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017; 19(1): 70. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796020/
  8. Tamburini B, Di Liberto D, Pratelli G, Rizzo C, Barbera L, Lauricella M, Carlisi D, Maggio A, Palumbo Piccionello A, D’Anneo A, Caccamo N, Guggino G. Extra Virgin Olive Oil Polyphenol-Enriched Extracts Exert Antioxidant and Anti-Inflammatory Effects on Peripheral Blood Mononuclear Cells from Rheumatoid Arthritis Patients. Antioxidants (Basel). 2025 Jan 31;14(2):171. doi: 10.3390/antiox14020171. PMID: 40002358; PMCID: PMC11851824. Available from: https://pubmed.ncbi.nlm.nih.gov/40002358/
  9. Perveen T, Hashmi BM, Haider S, Tabassum S, Saleem S, Siddiqui MA. Role of monoaminergic system in the etiology of olive oil induced antidepressant and anxiolytic effects in rats. ISRN Pharmacol. 2013 Jul 10;2013:615685. doi: 10.1155/2013/615685. PMID: 23936669; PMCID: PMC3725699. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3725699/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Onion (Pyaaz): Uses, Benefits, Side Effects and More!

Introduction

Onion is the most regularly used ingredient in Indian cooking and one of the most widely farmed and consumed vegetables worldwide1. Allium cepa (commonly known as onion) is a perennial (plant that lives for several years) herb with an underground bulb and a stem. Onions are members of the Liliaceae family. Most commercially grown onions are produced from the plant’s thin, black seeds. Because of their flavour and nutritional benefits, onions are highly valued and stored as pickles2. Onion is known by many other names, including basal, basl, cebolla, cebolla morada, cepa bulb, cepolla, cipolla, cuhanh, Spanish onion, tamanegi, Madras oignon, oignon, red globe onion, Zwiebel, yellow Bermuda onion, piyaj, piyaz, ralu lunu, sibuyas, loyon, and others3.

Onion grows in both warm and cold climates, in various soil types ranging from dry to moist and mineral-based soils, and is geographically widespread in South West Asia. Shoots, seeds, and bulbs are used to make medicine3.

Onions are the world’s oldest cultivated vegetable. The colour of red onions is mainly attributable to anthocyanins found in the cells of the bulb’s scale leaves. The onion is a multi-use vegetable that is eaten fresh as a salad or used in a variety of processed items. Onions might have various potential health uses in humans4.

Nutritional Value of Onion

The nutritional content of onion (per 100 g wet weight) is given below:

Onion (Pyaaz) bulbs and leaves contain a large number of phytoconstituents such as cyaniding glycosides, prostaglandins, quercetin, sterols, phenol compounds, catechol, protocatechuic acid (in the dried brown outer scale), and diosgenin (in the blossoms and bulbs). Onion oil has a higher concentration of mono, di, tri, tetra-sulphides, thiophene, and thiol compounds. Selenium, quercetin, flavanols, cysteine sulfoxides, flavonoids, allylsulfides, organosulfur compounds, thiosulfinates, cycloallin, fructose, sulphur and seleno compounds, sulfinates, xylose, galactose, glucose, and mannose are also found in onions3.

Potential Uses of Onion

Various properties of onion are listed below.

Though we have tears in our eyes while cutting it in our kitchens, onion is highly nutritious. It is rich in various vitamins like vitamins B1, B6, C, K. It is also rich in biotin and folic acid and minerals like calcium, and flavonoids that act as antioxidants. Additionally, it is also a good source of sulphur which might be beneficial for liver health12.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Onion

1. Potential Uses of Onion for Cancer

cancer

The potential antioxidant, cytotoxic (toxic to cells), and anti-inflammatory properties of onion peel extract are due to quercetin, which might aid in suppressing the production of reactive oxygen species and might help against oxidative cell damage1.

According to a study7, the potential antiproliferative action of onion peel extract on cancer cell lines (human colon cancer cell line, human osteosarcoma cell line) might be due to a synergistic effect of various bioactive compounds (phytochemicals and flavanols) present in the onion peel.

Another study7 found that onion peel extracts might have potential anticancer properties against breast cancer. Cancerous cells exhibit unregulated cell growth as well as abnormalities in apoptotic (cell death) processes. Red onion peel extract might lower cell proliferation and may improve cell cycle arrest in breast cancer cell lines apparently by suppressing a signalling system (which plays a critical role in cell cycle progression) in cancerous cells. But, all these claims need to be properly backed up by clear-cut evidence. Furthermore, serious conditions such as cancer must be properly diagnosed and treated by a qualified doctor. Kindly consult a doctor and do not self-medicate.

2. Potential Uses of Onion for Infections

skin infections

Many fungi, bacteria, and viruses have been reported to be affected by onion extracts. According to a study8, the essential oils of three onions (red, green, and yellow) have potential antibacterial activity against specific pathogens such as Salmonella enteritidis, Fusarium oxysporum, Penicillium cyclopium, Staphylococcus aureus, and Aspergillus Niger. In studies, red onion extract has been demonstrated the potential to have more antibacterial capabilities than yellow and white onion extracts2.

One study9 found that P. aeruginosa associated with urinary tract infections might be inhibited by onion extract, implying its potentiality for urinary tract infections. Furthermore their essential oils might help limit the growth of dermatophyte fungi (pathogenic fungi that grow on skin, hair, and nails). Onion extract might help reduce the growth of fungi like Fusarium oxysporum and Aspergillus Niger as well. Therefore, onion might be effective against various fungal, bacterial and viral infections. Further studies are needed to establish this ability of onion extracts.

3. Potential Uses of Onion for Obesity

obesity

According to a recent animal study1, quercetin from onion peel extracts was found to have potential anti-obesity properties. Onion peel extract might help suppress fat accumulation and triglyceride content maybe by inhibiting adipogenesis. One clinical trial investigation on obese healthy women who were administered quercetin rich-onion peel extract capsules might prove to be beneficial for weight management. However, these studies are limited and require wider studies to prove their true impact. Therefore, kindly consult a doctor for healthy weight management methods.

4. Benefits of Onion for the Brain

brain

Researchers1 have studied the brain-protective impact of onion husk extract. It might have a brain-protective effect by helping to raise the brain’s antioxidant levels. Onion solid waste extracts can certain enzymes which might be helpful for Alzheimer’s disease. This extract might also have a memory-enhancing effect which might be due to its antioxidant effect or due to the inhibition of certain enzymes and pathways.

Onion might also have an antidepressant potential. Various researchers have observed that the onion bulb might have anxiolytic, antidepressant, and memory-boosting capabilities. These activities need to be proved by more concrete research.

5. Potential Uses of Onion for the Heart

heart

According to an animal study10, blood lipid and glucose levels reduced dramatically in animals treated with quercetin-rich onion peel extract. There was, however, no effect on cholesterol. Prothrombin time and platelet aggregation were reduced by downregulating several pathways, ultimately reducing thrombosis (blood clotting), indicating that onion peel extract has antithrombotic (prevention of clot formation) effects that might be attributed primarily to quercetin and its derivatives found in onion peel1.

Scientists have discovered that onion peel extract might have the potential to help with hypercholesterolemia (an excess of cholesterol in the bloodstream) in an animal model. Thus, onion peel extract supplementation led to lower blood levels of low-density lipoprotein cholesterol and higher high-density lipoprotein cholesterol, which might ultimately be helpful for heart diseases1. Kindly consult a doctor for heart diseases. Do not self-medicate.

6. Potential Uses of Onion for Diabetes

diabetes

According to one study1, onion skin extracts might inhibit sucrase, α-glucosidase, maltase, and α-amylase enzymes. In an animal model, onion skin extracts significantly reduced blood glucose levels, implying that quercetin (phenolic phytochemicals) may have a sugar-lowering effect.

The administration of onion solid waste extracts may enhance insulin sensitivity and might reduce the oxidative stress in the liver and plasma-free fatty acids. Hence, the hypoglycemic (blood sugar lowering) effect of onion solid waste extracts might be due to lipid metabolism, reduced oxidative stress, and modulated proinflammatory cytokines. However, please consult a doctor for proper diagnosis and treatment of diabetes. Do not self-medicate.

7. Potential Uses of Onion as an Antioxidant

onion

According to studies2, onions may have antioxidant potential due to high levels of organosulfur compounds, polyphenols, and flavonoids, all of which are natural antioxidants. The study reports revealed that onion had higher antioxidant activity despite having lower organosulfur levels than garlic.

8. Potential Uses of Onion for the Bone

bone health

A study11 has investigated the effect of onion on osteoporosis, which is characterised by bone mineral density reduction. The cell line investigations revealed that onion extract might inhibit osteoclastogenesis (formation of bone-resorbing cells, osteoclasts) process. According to another study, postmenopausal women supplemented with onion juice had increased bone marrow density. Therefore, onion might be helpful for bone.

9. Potential Uses of Onion for Inflammation

reduces inflammation

In an animal study2, a red onion bulb extract might help reduce lymphocyte and eosinophil numbers (inflammatory cells) in the blood and bronchoalveolar lavage fluid (fluid collected from the lungs). Another study showed that onion extract reduced proinflammatory cytokines in microglia (brain) cells, and hence might help against brain inflammation.

The onion bulb extracts might reduce the overall counts of white blood cells and lung inflammatory cells, such as eosinophils, neutrophils, and monocytes, in animal models2. Therefore, it might be helpful for inflammation.

10. Potential Uses of Onion for the Liver

liver health

Researchers2 studied the effects of onion extract on liver damage in animal models. Onion apparently reduced alanine aminotransferase and total serum bilirubin levels but did not affect aspartate aminotransferase, alkaline phosphatase, or lactate dehydrogenase levels. This may indicate that onion extracts may have possible liver protective effects. However, more research is required to prove these possible effects.

Though there are studies that show the potential uses of onion in various conditions, but these are insufficient and there is a need of further studies to establish the true extent of the benefits of onion on human health.  

Studies12 imply that onion is a good source of a flavonoid called quercetin, a powerful antioxidant. It is mainly found in the skin of the onion and has various health benefits. It might be useful in reducing cholesterol, avoiding blood thinning and clotting, and fighting asthma, diabetes, and other infections. It might also exhibit antiviral, antibiotic, anti-inflammatory and sedative properties.

Dr. Rajeev Singh, BAMS

How to Use an Onion?

Onion can be used in the following ways:

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Also Read: Lady Finger: Uses, Benefits, Side effects and More!

Side Effects of Onion

There are no major side effects of onion reported by far. If you experience any side effects, seek immediate medical help from your doctor who has prescribed it to you. They will be the best guide for providing proper treatment to overcome side effects.

Also Read: Dhania (Cilantro): Uses, Benefits & Side Effects

Precautions to Take with Onions

Onion is a regular food item but if you plan to take onion for its health benefits you should follow general precautions. Safety studies of onion on pregnant and breastfeeding women have not been documented. Likewise, no research on the safe use of onion in children has been documented. Therefore, it should only be taken under the supervision and advice of a physician.

Also Read: Karela (Bitter Gourd): Uses, Benefits, Side Effects and More!

Interactions with Other Drugs

There is not much information available on how onion interacts with other medications. Hence, one should consult a doctor before taking onion if they take any other drug or supplement.

Frequently Asked Questions (FAQs)

What is onion (Pyaaz)?

Onion is a perennial herb with an underground bulb and a stem2.

Is onion a vegetable?

Yes, it isthe most widely farmed and consumed vegetable worldwide1.

Is onion good for weight loss?

Yes, onion might help in weight management . The presence of quercetin in onion exerted anti-adipogenetic (inhibition of formation of fat cells) activity in an animal study1. There is a requirement for more research to scientifically back up such claims.

Is onion good for diabetes?

Onion might be helpful for diabetes. Onion extracts might have a blood sugar lowering effect by potentially inhibiting α-amylase and α-glucosidase enzymes1. Kindly ensure that you consult a doctor for proper diagnosis and treatment of conditions like diabetes.

Is raw onion good for health?

Raw onion might be good for health.It might be helpful for diabetes, cardiovascular illness, and stomach cancer2. However, the potential uses of raw onion for health need to be ascertained by more research. Consult a doctor before using onion for its health benefits.

What is the chemical composition of onion bulbs?

Onion bulbs and leaves contain many phytoconstituents such as cyaniding glycosides, prostaglandins, quercetin, sterols, phenol compounds, catechol, protocatechuic acid (in the dried brown outer scale), and diosgenin (in the blossoms and bulbs) and nutrients like proteins, fats and carbohydrates3.

Is onion good for the liver?

Onion might be good for the liver. Onion extracts were found to have potential liver-protective effects by probably helping lower the levels of serum enzymes such as alkaline phosphates, aspartate aminotransferase and alanine aminotransferase in an animal model2. More research is needed to prove such claims. Therefore, kindly consult a doctor for liver disease and do not self-medicate.

Is onion oil good for hair growth?

Onion might be helpful for hair growth. According to a study6, the topical application of onion juice may be beneficial for patchy alopecia (hair loss) as it might help in the growth of coarse terminal hairs. However, such effects need to be proved by more.

References

  1. Kumar M, Barbhai MD, Hasan M, Punia S, Dhumal S, Rais N, et al. Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities. Biomed Pharmacother. 2022; 146: 112498. Available at: https://pubmed.ncbi.nlm.nih.gov/34953395/
  2. Chakraborty AJ, Uddin TM, Zidan M, Redwan BM, Mitra S, Das R, Nainu F, Dhama K, Roy A, Hossain M, Khusro A. Allium cepa: A Treasure of Bioactive Phytochemicals with Prospective Health Benefits. Evid-Based Complement Altern Med. 2022; 2022: 1-27. Available at: https://www.hindawi.com/journals/ecam/2022/4586318/ 
  3. Battagani D, Jada Naga L, Rayadurgam N. Review on Phytochemicals and Pharmacological Studies of Allium cepa (Onion). Int J Pharm Sci Rev Res. 2021; 68(1): 85-91. Available at: https://globalresearchonline.net/journalcontents/v68-1/15.pdf 
  4. Sidhu JS, Ali M, Al-Rashdan A, Ahmed N. Onion (Allium cepa L.) is potentially a good source of important antioxidants. J Food Sci Technol. 2019; 56(4): 1811-1819. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443770/
  5. Bora K, Sharma A. Phytoconstituents and therapeutic potential of Allium cepa Linn.-A Review. Pharmacog Rev. 2009; 3(5): 170-180. Available at: https://www.phcogrev.com/sites/default/files/PhcogRev-3-5-170.pdf
  6. Semalty M, Semalty A, Joshi GP, Rawat MS. Hair growth and rejuvenation: an overview. J Dermatol Treat. 2011; 22(3): 123-132. Available at: https://pubmed.ncbi.nlm.nih.gov/20536276/
  7. Uttarawichien T, Khumsri W, Suwannalert P, Sibmooh N, Payuhakrit W. Onion Peel Extract Inhibits Cancer Cell Growth and Progression through the Roles of L1CAM, NF-κB, and Angiogenesis in HT-29 Colorectal Cancer Cells. Prev Nutr Food Sci. 2021 Sep 30;26(3):330-337. doi: 10.3746/pnf.2021.26.3.330. PMID: 34737994; PMCID: PMC8531428. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8531428/
  8. Benkeblia N. Antimicrobial activity of essential oil extracts of various onions (Allium cepa) and garlic (Allium sativum). Lebensm-Wiss u-Technol (LWT – Food Sci Technol). 2004;37(2):263–268. doi:10.1016/j.lwt.2003.09.001. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0023643803001671
  9. Newman JN, Floyd RV, Fothergill JL. Invasion and diversity in Pseudomonas aeruginosa urinary tract infections. J Med Microbiol. 2022 Mar;71(3):001458. doi: 10.1099/jmm.0.001458. PMID: 35275806; PMCID: PMC9176269. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9176269/
  10. Brüll V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Müller C, Langguth P, Alteheld B, Fimmers R, Naaf S, Zimmermann BF, Stehle P, Egert S. Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial. Br J Nutr. 2015 Oct 28;114(8):1263-77. doi: 10.1017/S0007114515002950. Epub 2015 Sep 2. PMID: 26328470; PMCID: PMC4594049. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4594049/
  11. Zhang D, Wang X, Sun K, Guo J, Zhao J, Dong Y, Bao Y. Onion (Allium cepa L.) Flavonoid Extract Ameliorates Osteoporosis in Rats Facilitating Osteoblast Proliferation and Differentiation in MG-63 Cells and Inhibiting RANKL-Induced Osteoclastogenesis in RAW 264.7 Cells. Int J Mol Sci. 2024 Jun 19;25(12):6754. doi: 10.3390/ijms25126754. PMID: 38928460; PMCID: PMC11203775. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11203775/
  12. Sharma A. Nutritional benefits of onion. Facts for You [Internet]. April 2014 [cited 2026 Jan 5]. Available from: https://efy.efymag.com/admin/issuepdf/27-30_Onion_FFYApril-14.pdf

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Karela (Bitter Gourd): Uses, Benefits, Side Effects and More!

Introduction

Karela, also known as Momordica charantia L., belongs to the family Cucurbitaceae. It is commonly known as balsam pear, bitter gourd, bitter melon, karela, or kugua. Its fruit has been used as a vegetable for thousands of years. It is widely distributed in tropical and subtropical regions worldwide. It is called ‘bitter melon’ or ‘bitter gourd’ as the entire plant, including the fruit, tastes very bitter. Karela is widely cultivated in India, China, Japan, Malaya, Thailand, Vietnam, Singapore, Colombia, Brazil, Amazon, Cuba, East Africa, Haiti, Ghana, Mexico, Nicaragua, New Zealand, Panama, the Middle East, the Central and South America1.

The vernacular names of Karela are Karavelli in Sanskrit; Karelo in Gujrati; Karli in Marathi; Baramasiya in Bengali; Kaypa in Malayalam; Karali in Kannada; Kakara in Telugu; Pakar in Tamil.

Nutritional Value of Karela

Karela has the following nutritional value2:

Properties of Karela

The properties of karela include3:

Potential Uses of Karela

1. Potential Uses of Karela for Diabetes

The Karela extract is traditionally used as vegetable insulin as it might have antioxidant and antidiabetic properties. Its antidiabetic effect is tested in both animals and humans. When tested in an animal model4, the entire plant, including fruit pulp and seed, showed potential antidiabetic properties. Its fruit was found to have more potential effects on diabetes. It might either control the release of insulin or may change the metabolism of glucose5.

Karela contains a few chemicals, including glycoside, charantin, vicine, karavilosides, and polypeptide-p (plant insulin). These chemicals might improve blood sugar levels by raising the glucose uptake and synthesis of glycogen in the liver, fat, and muscle cells6. Kindly consult a doctor for the proper diagnosis and treatment of serious conditions such as diabetes. Please do not self-medicate.

2. Potential Uses of Karela for Antioxidant Properties

The phenolic compounds in karela are a potentially excellent natural source of food antioxidants. Phenolic compounds might have the ability to lower cholesterol, blood pressure, and the incidence of heart-related diseases and cancer7. However, more research is required.

3. Potential Uses of Karela for Cancer

The karela extract might help modify the signalling pathways involved in breast cancer. It might block the growth of breast cancer cells and may be used as a dietary supplement to help against breast cancer8. The fruits, green leaves, stems, and f karela seeds have several active proteins and steroids. These proteins might have potential anticancer activity. However, serious conditions such as cancer should be diagnosed and treated by a doctor. Therefore, consult a doctor and do not self-medicate.

I came across a fascinating study13 that revealed something amazing about karela. According to the study, karela extract may have the power to speed up the healing process of gastric ulcers in rats. However, it’s important to note that studies on humans are needed to confirm these exciting claims.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

4. Potential Uses of Karela for Malaria

Asians, Colombians, and Panamanians have traditionally known karela as a helpful plant against malaria. Various studies9 have confirmed that several species of karela may have antimalarial properties. However, please consult a doctor and do not self-medicate.

5. Potential Uses of Karela for Healing Wounds

A series of abnormalities linked with diabetes and delayed wound healing are lowered immune response, reduced formation of new blood vessels, deficiency of growth factors, and reduced collagen production. When karela fruit ointment was applied to the rat (diabetic rat), it showed a potential to improve wound closure and which may help enhance a gene that helps in cell growth. Therefore, it might be beneficial for the healing of the wound1. However, more research is required to prove such effects on humans.

Though some studies show the potential uses of karela in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of karela on human health.

In my opinion, karela with a bit of a tangy taste, might actually benefit the immune cells. It’s true! It may help calm down inflammation and act as an immunomodulator, which is like being a saviour for your immune response11.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Karela?

It is mostly used as:

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Also Read: Sabudana (Sago Pearls): Uses, Benefits, Side Effects & More!

Side Effects of Karela

If you experience any of these side effects, you must consult your doctor immediately.

Based on my observations, karela has two tasty options: young shoots and not-quite-ripe fruits. The fruits are bitter, but you may make them less bitter by blanching or soaking them in salty water. Inside the yellow fruits, you find a treasure trove of good stuff like carotenoids, iron, phosphorous, and vitamin C12.

Dr. Rajeev Singh, BAMS

Precautions to Take with Karela

From what I have known and read, karela is a versatile plant that can be included in our diet for better health! It is not only tasty but also may have medicinal benefits. It might keep worms away, relieve pain, help with haemorrhoids, and even soothe rashes12.

Dr. Smita Barode, B.A.M.S, M.S. 

Also Read: Cashew Nuts: Uses, Benefits, Side Effects & More

Interactions with Other Drugs

Since karela lowers the blood sugar level, taking karela along with diabetes medicines might lower the blood sugar level too much. Therefore, monitor your blood sugar level carefully while taking karela. Discuss your ongoing treatments and medications with your doctor before taking karela for its benefits.

Also Read: Bottle Gourd (Lauki): Uses, Benefits, Side Effects and More!

Frequently Asked Questions (FAQs)

Can we eat karela during pregnancy?

No, please do not consume karela during pregnancy. It is unsafe during pregnancy as it contains certain chemicals that might be harmful to pregnancy.

Is karela good for the kidney?

Karela may be good for the kidneys. Traditionally, karela has been used in China, Cuba, and India for kidney problems and kidney stones10. However, more research is required.

Are there any side effects of karela?

Yes, there are some side effects of karela. In some people, karela might upset the stomach. Karela might cause a rash when applied to the skin. Some people may get headaches. Karela may also lower the blood sugar level. Visit your doctor if you experience any side effects.

Can karela cure malaria?

Karela might be helpful against malaria. It has been traditionally known by Asians, Colombians, and Panamanians as a helpful plant against malaria10. However, a study on the antimalarial effect of karela in humans is required.

Is karela good for health?

Yes, karela may be good for health and may be helpful for diabetes mellitus, anorexia (lack of appetite for food), blood impurities, diarrhoea, hangover, piles, pyorrhoea, skin infections, and respiratory problems. It also has antimicrobial, anticancer, wound healing, and antimalarial properties

How to use karela?

Karela can be used as a vegetable, karela juice, karela leaf tea, fried karela chips, dehydrated karela rings, and karela pickle.

Can karela be used during breastfeeding?

It is advised not to use karela during breastfeeding. Consult your doctor before using karela during breastfeeding.

Does karela cause allergies?

Yes, karela can cause allergy, and the signs of an allergy are itching, shortness of breath, or rash. Avoid karela if you have a known allergy to karela or any member of the family Cucurbitaceae, including honeydew, casaba, Persian melon, cantaloupe, and muskmelon.

References

  1. Jia S, Shen M, Zhang F, Xie J. Recent Advances in Momordica charantia: Functional Components and Biological Activities. International Journal of Molecular Sciences. 2017 [cited 2025 May 6]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5751158/
  2. Balsam-pear (bitter gourd), leafy tips, cooked, boiled, drained, without salt – Nutrients – SR Legacy. USDA FoodData Central. [cited 2025 May 6]. Available from: https://fdc.nal.usda.gov/food-details/168392/nutrients 
  3. Jia S, Shen M, Zhang F, Xie J. Recent advances in momordica charantia: Functional components and biological activities. Int J Mol Sci. 2017;18(12). Available at: https://pubmed.ncbi.nlm.nih.gov/29182587/
  4. Joseph B, Jini D. Antidiabetic effects of Momordica charantia (bitter melon) and its medicinal potency. Asian Pacific Journal of Tropical Disease [Internet]. 2013 Mar 16;3(2):93–102. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4027280/ 
  5. Gupta M, Sharma S, Gautam AK, Bhadauria R. Momordica charantia linn. (Karela): Nature’s silent healer. ResearchGate. 2011 [cited 2025 May 6]. Available from: https://www.researchgate.net/publication/285966662_Momordica_charantia_linn_Karela_Nature%27s_silent_healer 
  6. Nagarani G, Abirami A, Siddhuraju P. Food prospects and nutraceutical attributes of Momordica species: A potential tropical bioresources – A review. Food Science and Human Wellness. 2014 [cited 2025 May 6]. Available from: https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/momordica
  7. Najm WI. An overview on nutraceuticals and herbal supplements for diabetes and metabolic syndrome. In: Elsevier eBooks. 2012 [cited 2025 May 6]. p. 355–65. Available from: https://www.sciencedirect.com/topics/food-science/bitter-gourd
  8. Psilopatis I, Vrettou K, Giaginis C, Theocharis S. The role of bitter melon in breast and gynecological cancer prevention and therapy. International Journal of Molecular Sciences. 2023 [cited 2025 May 6]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10219438/#sec10-ijms-24-08918 
  9. Ahmad N, Hasan N, Ahmad Z, Zishan M, Zohrameena S. MOMORDICA CHARANTIA: FOR TRADITIONAL USES AND PHARMACOLOGICAL ACTIONS. Journal of Drug Delivery and Therapeutics. 2016 [cited 2025 May 6]. Available from: https://www.researchgate.net/publication/296988488_MOMORDICA_CHARANTIA_FOR_TRADITIONAL_USES_AND_PHARMACOLOGICAL_ACTIONS 
  10. Kumar KPS, Bhowmik D. Traditional medicinal uses and therapeutic benefits of Momordica charantia Linn. Int J Pharm Sci Rev Res. 2010;4(3):23–8. Available at: https://globalresearchonline.net/journalcontents/volume4issue3/Article%20004.pdf 
  11. Kwatra D, Dandawate P, Padhye S, Anant S. Bitter Melon as a Therapy for Diabetes, Inflammation, and Cancer: a Panacea? Current Pharmacology Reports. 2016 [cited 2025 May 6]. Available from: https://www.researchgate.net/publication/291419012_Bitter_Melon_as_a_Therapy_for_Diabetes_Inflammation_and_Cancer_a_Panacea 
  12. Momordica charantia (bitter gourd). CABI Compendium. [cited 2025 May 6]. Available from: https://www.cabidigitallibrary.org/doi/10.1079/cabicompendium.34678
  13. Goo KS, Ashari S, Basuki N, Sugiharto AN. The Bitter Gourd Momordica charantia L.: Morphological Aspects, Charantin and Vitamin C Contents. IOSR Journal of Agriculture and Veterinary Science. 2016 [cited 2025 May 6]. Available from: https://doi.org/10.9790/2380-0910017681

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Guggul: Uses, Benefits, Side Effects and More!

Introduction

Guggul is an oleo-gum resin obtained from the bark of Commiphora wightii and belongs to the family Burseraceae. It is obtained as an exudate from the tapping of branches and stems of the guggul tree. It is found in dry areas of India, Pakistan, and Bangladesh. In India, it is found in Gujarat, Assam, Rajasthan, Karnataka, and Madhya Pradesh1. The guggul tree is a small, bushy tree and has thorny branches. It makes yellowish gum resin in small ducts found all over its bark. The guggul tree is hit by making a cut on its bark, due to which the resins flow out and are allowed to harden before they are collected1. Guggul has been used in the Indian traditional system for thousands of years to manage inflammation, gout, rheumatism, arthritis, obesity, and lipid metabolism disorders. It is also known as Guggula, Gugar, Guggal, and Indian bdellium1.

Other vernacular names of guggul are:

Chemical Composition of Guggul

Guggul is an oleo gum resin and contains gum, resin and volatile oils (small quantity). It contains amino acids, sugars, essential oils, flavonoids, cembrene, camphorene, allycembrol, and ellagic acid3.

Uses of Guggul

Guggul has the following therapeutic properties4:

Potential Uses of Guggul

Guggul possesses many properties, which may show potential uses against many disease conditions.

1. Potential Uses of Guggul for Arthritis and Inflammation

Arthritis

Several studies1 have confirmed that guggul is beneficial for arthritis and inflammation and has anti-inflammatory and anti-arthritic activity. The guggul extract was evaluated for anti-arthritic activity in various animal models. It was found that it blocked the disease’s development and lowered the severity of the disease. Several studies have confirmed that guggul might be helpful for arthritis and inflammation and show anti-inflammatory and anti-arthritic properties. The guggul extract was also evaluated for anti-arthritic activity in various animal models. In studies it was found that it blocked the disease’s development and lowered the effect of arthritis1. However, do not use guggul as an alternative to medicinal treatment. Talk to a healthcare provider before using guggul for arthritis.

2. Potential Uses of Guggul for Skin Diseases

skin infections

In a study1 gugulipid (extract of guggul) was found to be effective in managing nodulocystic acne (a severe form of inflammatory acne that cauIn a study gugulipid (extract of guggul) was found to be effective in managing nodulocystic acne (a severe form of inflammatory acne that causes cysts and nodules on the face). In a human trial, too it was found to have some benefits for nodulocystic acne. The patients who had oily faces showed better results. However, talk to a skin doctor or specialist before using any herbal remedy on your face.

Over the years, I have observed that conditions like eczema and psoriasis, which involve inflammation of the skin, can be challenging to manage. However, I have found that Guggulu, a natural remedy, might offer some relief. Based on studies, using a cream containing Boswellia, an active component of Guggulu, can potentially reduce the reliance on corticosteroid creams and improve symptoms such as redness and superficial skin issues.

Dr. Rajeev Singh, BAMS

3. Potential Uses of Guggul for Obesity

Obesity

According to a study1 guggul showed a lipid-lowering effect in obesity and atherosclerosis (a condition where fat deposits in the arteries). The lipid-lowering effect of guggul was studied in animals as well as humans. Guggul contains bioactive compounds that might be responsible for hypolipidemic activity. You should talk to a healthcare provider before using any herb to manage weight. In addition talking to a dietician will help you make better dietary choices.

4. Potential Uses of Guggul for Heart Related Diseases

heart

Guggulsterone (plant steroid) found in guggul may show the heart-protective property. Guggulsterone was tested in an animal model for heart protective activity. It was found to lower cholesterol, phospholipid, and glycogen levels and protect the heart against damage1. However, if you are suffering from heart problems, talk to a doctor and get a proper diagnosis and treatment. 

In my experience, I have observed that Guggulu, a herbal remedy, may have potential effectiveness in managing asthma symptoms. It is believed that Guggulu’s anti-inflammatory properties could help reduce airway inflammation and improve respiratory function7.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Guggul?

Your Ayurvedic physician will prescribe the form and dose as per your requirement. Guggul can be used as:

You must consult a qualified doctor before taking guggul or any herbal supplements. Likewise do not discontinue or replace an ongoing modern medical treatment with an ayurvedic herbal preparation without consulting a qualified doctor. 

Side Effects of Guggul

Side effects associated with guggul use are:

Before using guggul or any herbal remedy, consult your doctor about the side effects associated with its use. It will help you make well-informed choices about your health.

Precautions to Take with Guggul

Even though guggul is generally considered relatively safe, it is better to use it with caution1:

Also, before taking guggul for its health benefits, consult your healthcare provider about the possible precautions associated with its use.   

Interactions with Other Drugs

Gugulipid (guggul extract) may interact with blood pressure medicines like diltiazem and propranolol. It reduces the absorption of these medicines. Taking guggul along with these medicines may lower the effectiveness of these drugs6. If you are taking any medicines, talk to your healthcare provider about the possible interactions of the treatment with other herbs and drugs. This will help you avoid unwanted side effects and interactions. 

Also Read: Kutajarishta: Uses, Benefits, Side Effects, and More!

Frequently Asked Questions (FAQs)

Is guggul helpful in obesity?

Guggul might help deal with obesity. It has been used in Ayurveda for several years for managing obesity1. However, talk to a healthcare provider before using herbal remedies to manage weight.

Is guggul good for the heart?

Yes, guggul might be good for the heart as it may show heart-protective activity3. If you are experiencing any heart problems, consult a doctor and get a proper diagnosis and treatment.

Can guggul be used during pregnancy?

There is no sufficient information about the safe usage of guggul during pregnancy. However, avoid taking guggul during this time to be safer. You must consult your doctor if you want to take guggul during pregnancy.

Is there any side effect of guggul?

It is mentioned in Ayurveda that when raw guggul is taken, it may sometimes cause diarrhoea, skin rashes, headache, mild nausea, irregular menstruation and liver damage (at high doses). In addition, a study found that some people had temporary side effects like fatigue and stomach-related issues1. Therefore, before using guggul or any herbal remedy, consult your doctor about the side effects associated with its use.

Does guggul interact with any medicine?

Guggul may interact with blood pressure medicines like diltiazem and propranolol and may lower the effectiveness of these drugs6. Therefore, If you are taking any medication, talk to your healthcare provider about the possible interactions of the treatment with other herbs and medicines.

Is guggul good for arthritis?

Guggul is good for arthritis. It showed anti-arthritic activity when tested in an animal model. However, its anti-arthritic activity in humans is yet to be tested1. You should talk to a doctor before using any herbal remedy for arthritis.

Does guggul lower cholesterol?

Guggul was found to lower cholesterol levels in an animal model1. However, its effect on humans is yet to be tested. Therefore, do not use it as an alternative to medicinal treatment. Talk to a doctor before you use guggul for managing cholesterol.

Is guggul safe?

Yes, guggul is considered safe in prescribed doses, but some studies found few side effects associated with its usage. Therefore, it is best to consult a doctor before taking guggul1.

In what forms is guggul available?

Guggul is available as powder, tablet, and capsules2,5. Consult a doctor before taking guggul for any health condition.

References

  1. Sarup P, Bala S, Kamboj S. Pharmacology and Phytochemistry of Oleo-Gum Resin of Commiphora wightii (Guggulu) . Scientifica (Cairo). 2015;2015:1–14. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637499/
  2. Health MOF, Welfare F. The Ayurvedic Pharmacopoeia of India, Part 1. 2001;3:129–30. Available at: http://www.ayurveda.hu/api/API-Vol-1.pdf
  3. Priyanka P, Sanjeev MK, Kumar GV, Jitender S, Sweety. Gum guggul: An ayurvedic boom. Int J Pharmacogn Phytochem Res. 2014;6(2):347–54. Available from: https://impactfactor.org/PDF/IJPPR/6/IJPPR,Vol6,Issue2,Article37.pdf
  4. Vikaspedia. Commiphora wightii [Internet]. Available from: https://vikaspedia.in/agriculture/crop-production/package-of-practices/medicinal-and-aromatic-plants/commiphora-wightii
  5. Ahmed R, Wang YH, Ali Z, Smillie TJ, Khan IA. HPLC Method for Chemical Fingerprinting of Guggul (Commiphora wightii)-Quantification of E- and Z-Guggulsterones and Detection of Possible Adulterants. Planta Med. 2016;82(4):356–61. Available from: https://www.semanticscholar.org/paper/HPLC-Method-for-Chemical-Fingerprinting-of-Guggul-E-Ahmed-Wang/4f3ca400664e5173813aa679c80d5e1685daf3a4
  6. Dalvi SS, Nayak VK, Pohujani SM, Desai NK, Kshirsagar NA, Gupta KC. Effect of gugulipid on bioavailability of diltiazem and propranolol. J Assoc Physicians India. 1994;42(6):454–5. Available from: https://pubmed.ncbi.nlm.nih.gov/7852226/
  7. Dadoriya P, Dey YN, Sharma D, Yadav M, Wanjari MM, Gaidhani SN, Subhose V. In-vitro anti-inflammatory and antioxidant activities of an Ayurvedic formulation – Trayodashang Guggulu. J Herb Med. 2020;23:100366. Available from: https://www.sciencedirect.com/science/article/abs/pii/S2210803320300385

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Lemongrass: Uses, Benefits, Side Effects and More!

Introduction

Lemongrass, also called Cymbopogon citratus, is a plant that belongs to the family Gramineae or Poaceae. In Greek, ‘Cymbopogon’ means boat-beard. It is a fragrant, long-living plant that is native to Sri Lanka and South India. Today, it widely grows throughout Asia and tropical America. Freshly cut and slightly dried lemongrass leaves are used to extract essential oils that are further used for medicinal purposes1.

The common names of lemongrass are Sera, Verveine in Hindi; Citronella, Squinant in English; Cimbopogone in Italian; Citongrass in Swedish; Sereh in Indonesian; Zacate Limon in Mexican; Sakumau in Malaysia; Tej-sar in Ethiopia; Capim-cidrao, Capim-Santo in Brazil; Citronella in the USA; Limon out in Turkish; Ta-khrai in Thailand2.

Nutritional Value of Lemongrass

The nutritional composition in 100g of lemongrass is3:

Properties of Lemongrass

The many properties of lemongrass are as follows2, 4:

Potential Uses of Lemongrass

Lemongrass has many properties, because of which it shows potential uses in many disease conditions.

1. For Infection

The antimicrobial potential of lemongrass has been observed in lab-scale studies. However, more large-scale trials are needed to support the use of lemongrass for infections in humans. Therefore, you are advised to follow the advice of a doctor in case of infectious diseases.

2. For Heart Health and Obesity

Several studies6 have tested lemongrass as a hypoglycaemic (lowering blood sugar level) and hypolipidemic (lowering lipid in the blood) agent to reduce the risk of obesity and hypertension. It was found to lower high cholesterol levels in humans, thus showing heart-protecting activity. It was also found to help lose excess weight in overweight patients. However, if you experience any heart problems or want to lose weight, contact your doctor and follow the doctor’s advice.

3. For Inflammation

Tissue inflammation is considered one of the leading causes of serious health problems. It is found to be linked with diseases like diabetes, cancer, neurodegenerative disorders, cardiovascular (related to heart and blood vessels) disorders and rheumatoid arthritis. Several researchers reported that lemongrass contains polyphenols that may show anti-inflammatory properties and reduce inflammation7. However, before using lemongrass or other herbal remedies for health benefits, you should talk to a doctor or doctor.

4. For Anxiety

Many researchers have studied the anti-anxiety effects of lemongrass tea. An experiment6 found that the lemongrass decoction (concentrated solution) and lemongrass tea could show anti-anxiety effects when given to animals. However, if you struggle with anxiety, talk to a psychiatrist about your symptoms.  

5. For Stomach Health

The boiled and concentrated solution of lemongrass leaf stalk may be used to manage diarrhoea4. Lemongrass tea might be used to manage indigestion, stomach pain, and gastric ulcers by protecting the linings of the stomach4. If you experience stomach problems, consult your doctor before using lemongrass to aid your symptoms. Using herbal remedies without a doctor’s consultation can worsen the situation.

6. For Liver Health

The leaf extract of lemongrass was tested for its liver activity. It was found to be helpful for managing disorders or diseases of the liver8. However, if you are suffering from liver diseases, using any herb without consulting a doctor can damage the liver. Therefore, talk to your doctor before using lemongrass.

Though there are studies showing the benefits of lemongrass in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of lemongrass on human health. 

Based on my experience, I have observed that fresh leaves of lemongrass might have activity against Setaria digitata, a filarial parasite. Lemongrass may possess antifilarial properties, which could help in combating filarial infections11.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Lemongrass

Lemongrass can be used:

You must consult a qualified doctor before taking lemongrass or any herbal supplements. Likewise, do not discontinue or replace an ongoing modern medical treatment with an ayurvedic/herbal preparation without consulting a qualified doctor.

Over the years, I have observed that the fresh leaf of lemongrass essential oil may have larvicidal activity, which means it can potentially kill mosquito larvae. This activity could be beneficial in controlling mosquito populations and reducing the risk of mosquito-borne diseases11.

Dr. Smita Barode, B.A.M.S, M.S.

Side Effects of Lemongrass

Usually, lemongrass is considered safe for cooking, but if consumed in an excessive amount, it can cause side effects like:

Before using lemongrass or other herbs for their health benefits, talk to your doctor about the possible side effects. This will help you make well-informed choices.

Precautions to Take with Lemongrass

Lemongrass should be avoided during pregnancy, as there is a chance that it may start menstrual flow9. Also, an animal study10 was found to affect the embryo. Therefore, lemongrass should be avoided during pregnancy and breastfeeding.

Also, before taking lemongrass against any disease conditions, consult your doctor about the possible precautions and limitations of using lemongrass.

In my experience, lemongrass essential oil may have promising antinociceptive effects, meaning it may help reduce pain sensation. While it appears to work both locally and internally through the central nervous system, it’s important to note that individual responses may differ in each person11.

Dr. Rajeev Singh, BAMS

Interactions with Other Drugs

There is no sufficient information available. However, if you are taking medicines for a health condition, talk to your doctor about the possible interactions of the drug with other medications and herbs. It will help you avoid unwanted herb-drug interactions.

Frequently Asked Questions (FAQs)

Can lemongrass cure dandruff?

Lemongrass oil has anti-inflammatory and antimicrobial properties and is used in hair tonics to reduce dandruff. It might be useful in blocking the growth of fungi M. furfur, which is linked to dandruff.

Does lemongrass cure malaria?

In an animal study4, lemongrass was found to show anti-malarial effects. However, its anti-malarial effect in humans is yet unknown. Therefore, stick to the doctor’s advice and treatment to manage malaria. Do not use herbal remedies to cure malaria unless a doctor recommends it.

How to use lemongrass?

Lemongrass is used as lemongrass tea, oil, aromatic water, and in food for its lemon flavour. However, talk to a doctor about using lemongrass for its health benefits.

Can I use lemongrass during pregnancy?

No, lemongrass should not be used in pregnancy. There are chances that it can cause menstrual flow.

Is it safer to use lemongrass during breastfeeding?

No, lemongrass should be avoided during breastfeeding.

Are there any side effects of lemongrass?

Lemongrass should be used in moderation. Consuming in excess may cause side effects like dry mouth, tiredness, dizziness, frequent urination, increased appetite, and allergic reactions like rash and itching.Therefore, you are advised to consult a doctor before using lemongrass for its health benefits.

Is lemongrass good for cholesterol?

Lemongrass was beneficial for managing cholesterol levels in lab studies5. The lemongrass extract was found to lower high cholesterol levels in human trials. However, more studies are required to support the use of lemongrass in high blood cholesterol in humans. If you have high cholesterol, you need to follow the doctor’s advice on treatment.  

References

  1. Gurjar ES, Gowda KV, Gs N, Mishra S. Lemongrass: a traditional ethno-medicinal plant of India. ResearchGate. 2024 [cited 2025 May 15]. Available from: https://doi.org/10.5281/zenodo.10725291
  2. Shah G, Shri R, Panchal V, Sharma N, Singh B, Mann A. Scientific basis for the therapeutic use of Cymbopogon citratus, Stapf (Lemon grass). Journal of Advanced Pharmaceutical Technology & Research. 2011 [cited 2025 May 15]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3217679/
  3. Lemon grass (citronella), raw nutrition facts and analysis. NutritionValue.org. [Internet]. [cited 2025 May 15]. Available from: https://www.nutritionvalue.org/Lemon_grass_%28citronella%29%2C_raw_nutritional_value.html?size=100+g 
  4. Manvitha K, Bidya B. Review on pharmacological activity of Cymbopogon citratus. International Journal of Herbal Medicine. 2014 [cited 2025 May 15]. Available from: https://www.florajournal.com/archives/2014/vol1issue6/PartA/3.1.1.pdf 
  5. Ekpenyong CE, Akpan EE, Daniel NE. Phytochemical Constituents, Therapeutic Applications and Toxicological Profile of Cymbopogon citratus Stapf (DC) Leaf Extract. J Pharmacogn Phytochem. 2014;3(1):133–41. Available at: https://www.phytojournal.com/vol3Issue1/Issue_may_2014/32.1.pdf
  6. Olorunnisola SK, Asiyanbi -H. T., Hammed, A. M., Simsek S. Mini Review Biological properties of lemongrass : An overview. Int Food Res J. 2014;21(2):455–62. Available at: http://www.ifrj.upm.edu.my/21%20(02)%202014/4%20IFRJ%2021%20(02)%202014%20043.pdf 
  7. Silva H, Bárbara R. Exploring the anti-hypertensive potential of lemongrass—A comprehensive review. Biology. 2022 [cited 2025 May 15]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9598547/ 
  8. Rahim S, Taha E, Al-Janabi, Al-Douri B, Simon K, Mazlan A. Hepatoprotective effect of Cymbopogon citratus aqueous extract against hydrogen peroxide-induced liver injury in male rats. African Journal of Traditional, Complementary and Alternative Medicines. 2014 [cited 2025 May 15]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4202655/ 
  9. Santiago F, Peixoto M, Oliveira J, Coutinho M, Araújo C. Use of medicinal plants with teratogenic and abortive effects by pregnant women in a city in Northeastern Brazil. Revista Brasileira de Ginecologia e Obstetrícia. 2016 [cited 2025 May 15]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10309309/ 
  10. Da Silva II, Da Silva NPC, Marrs JA, Cadena PG. Essential oils produce developmental toxicity in zebrafish embryos and cause behavior changes in zebrafish larvae. Biomedicines. 2023 [cited 2025 May 15]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10603861/#sec5-biomedicines-11-02821
  11. Shah G, Shri R, Panchal V, Sharma N, Singh B, Mann A. Scientific basis for the therapeutic use of Cymbopogon citratus, Stapf (Lemon grass). Journal of Advanced Pharmaceutical Technology & Research. 2011 [cited 2025 May 15]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3217679/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Grapefruit (Chakotra): Uses, Benefits, Side Effects and More!

Introduction

Grapefruit is a citrus fruit which is scientifically known as Citrus paradisi. Grapefruits are medium sized fruits belonging to the Rutaceae (Citrus) family. It is a good source of vitamin C and other healthy nutrients. Grapefruits are hybrid fruits made of sweet oranges and pomelos. People often consume grapefruit for its various properties, but there is not enough evidence to support its use. Also, drug interactions with grapefruit are very well documented. Therefore, make sure to talk to a doctor or healthcare provider if you are taking certain medications1

You may want to enjoy grapefruits because of their pleasing flavour and desirable taste, but they can offer more. If you want to learn about this nutrient packed fruit, continue reading! 

Nutritional Value of Grapefruit

Grapefruit contains many nutrients, such as vitamins, minerals, carbohydrates, proteins, fats and fibres. The nutritional value of grapefruit per 100 grams of serving is given below: 

Nutritional value of grapefruit per 100 g of serving2  

Properties of Grapefruit

Grapefruits (Chakotra) are valuable due to the following properties: 

Potential Uses of Grapefruit for Overall Health

The potential advantages of grapefruit have been observed in many animal studies. However, some of these benefits have yet to be observed in humans, and there is a lack of research justifying the same. Therefore, if you are suffering from any disease or health condition, it is best to reach out to a healthcare professional and get a proper diagnosis and treatment.   

1. Potential Uses of Grapefruit for Oxidative Stress

stress

Free radicals are molecules generated in the body, causing oxidative damage to proteins, lipids, and deoxyribonucleic acid (DNA). Oxidative stress or damage in the body leads to the onset of many long-term diseases. Chemicals that destroy these free radicals help reduce the overall oxidative stress in the body and help avoid long term diseases. Grapefruits might possess good antioxidant activity. Consuming grapefruits may help in reducing oxidative stress in the body3.

2. Potential Uses of Grapefruit for Inflammation

inflammation

Inflammation is the body’s response to external stress, chemicals, pathogens, and injury. The process of inflammation is often associated with many severe illnesses of the heart, cancer, and diabetes. Grapefruit might possess anti-inflammatory properties, which may help reduce inflammation in the body3.

3. Potential Uses of Grapefruit for Bone Health

bone health

Structural deterioration of bones due to an imbalance between bone formation and resorption can lead to osteoporosis. Grapefruit might help maintain bone health. Grapefruit could positively affect bone health and promote bone formation, as per an animal study. Several other studies have shown that consuming grapefruit modulated bone strength in animal studies3. If you are suffering from any bone-related conditions, it is important that you follow your doctor’s advice and avoid using any herb or vegetable before consulting with your doctor.  

4. Potential Uses of Grapefruit for Cancer

cancer

Grapefruits are rich in many nutrients like vitamins and minerals, and phytochemicals. Consuming these nutrients from fresh fruits might have reinforcing effects on overall health. The antioxidant and anti-inflammatory properties of grapefruit may help avoid long term diseases like cancer3. Cancer is a severe illness and requires people to adhere to doctors’ advice thoroughly. Make sure to consult with your doctor before you use grapefruit for any health conditions.  

5. Potential Uses of Grapefruit for Weight Loss

In a trial conducted on obese patients, consuming grapefruits before meals were associated with significant weight management. Therefore, consuming grapefruits may help people who want to lose weight4. However, you need to get in touch with your healthcare provider or nutritionist before making any changes to your diet.   

Though there are studies that show the benefits of grapefruit in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of grapefruit on human health.   

I chanced upon research where I learnt that eating half of a fresh grapefruit before meals might actually help reduce high insulin levels and improve insulin resistance. So, if you want to manage your insulin and improve your overall health, consider adding grapefruit to your meals6.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Grapefruit?

Grapefruit is commonly consumed as food or in the form of juice1.

You must consult a qualified doctor before taking any herbal supplements. Likewise, do not discontinue or replace an ongoing medical treatment with an Ayurvedic/herbal preparation without consulting a qualified doctor.   

As per my observations, grapefruits might be an excellent choice for staying hydrated because they are more than 90% water. Not only does hydration support overall well being, but it may also play a crucial role in maintaining digestive health.

Dr. Smita Barode, B.A.M.S, M.S.

Side Effects of Grapefruit

Consuming grapefruits or grapefruit juice is possibly safe when taken in moderate amount by mouth, however

I may suggest grapefruit if you are looking for a natural way to manage blood pressure and cholesterol. During a study, individuals who consumed grapefruit three times a day for six weeks noticed a significant decrease in blood pressure and observed an improvement in their total cholesterol and LDL (bad) cholesterol levels. However, more research is needed to understand the full benefits of grapefruit for managing cardiovascular diseases7.

Dr. Rajeev Singh, BAMS

Precautions to Take with Grapefruit

Here are some general precautions you need to take when using grapefruits. 

NOTE: If you are suffering from any health condition, you need to consult a doctor about the herbs and fruits you should avoid. Also, avoid using grapefruit juice or any other juices for disease conditions without consulting with your healthcare provider.    

Interactions with Other Drugs

Major Interaction (Do not take this combination)

Drinking grapefruit juice with these medications might increase the effect and side effects of the medications: 

Drinking grapefruit juice with these medications might decrease the effect and side effects of these medications: 

Also Read: Durian: Uses, Benefits, Side Effects By Dr. Rajeev Singh

Moderate Interactions (Be cautious with this combination)

Be cautious while drinking grapefruit juice with these medications: 

Also Read: Goji Berry: Uses, Benefits, Side Effects By Dr. Rajeev Singh

Minor Interactions (Be watchful of such combinations)

If you are taking medications for any health condition, you need to consult your doctor about the fruits and vegetables to avoid. Also, before using grapefruit juice or any herb for its benefits, talk to your healthcare provider about potential precautions and interactions.  

Also Read: Onion (Pyaaz): Uses, Benefits, Side Effects and More!

Frequently Asked Questions (FAQs)

What are the benefits of grapefruit (Chakotra) juice for weight loss? 

Eating grapefruit may help with weight management. The weight management benefits were observed during a clinical trial conducted on obese patients4. However, you need to contact your healthcare provider before making any diet changes, as any changes can affect your overall health.  

What are the health benefits of grapefruit?  

Grapefruits are packed with essential nutrients and phytochemicals that might have antioxidant and anti-inflammatory properties. These properties help avoid many severe diseases. Also, eating grapefruits may help in maintaining bone health2,3. However, before using any fruit or vegetable for any health issue, reach out to your healthcare provider or doctor to get a diagnosis and proper treatment.   

What are the benefits of grapefruit for the skin?  

Grapefruit’s skin peel may have potent antioxidant and anti-inflammatory properties, which are suitable for overall health5. However, if you are suffering from any skin-related conditions, it is best to consult your skin doctor before using any herb or vegetable on your own.    

Does grapefruit have side effects?  

Grapefruit is commonly consumed as fresh fruit and juices and may be safe when used in moderate amounts. However, it should not be consumed in excess because it may cause side effects. Also, if you are taking any medication, talk to your healthcare provider about foods you should avoid. Grapefruit can interact with many drugs and change their activities1.

Is grapefruit safe during pregnancy?  

There is a lack of scientific resources supporting the safe use of grapefruit during pregnancy. You are advised to exercise precaution and use it in moderate amounts1. Also, you need to contact your physician before using any fruit juices during pregnancy.  

References

  1. MedlinePlus Supplements. Grapefruit [Internet]. [cited 2022 Jun 24]. Available from: https://medlineplus.gov/druginfo/natural/946.html 
  2. FoodData Central [Internet]. [cited 2022 Jun 24]. Available from: https://fdc.nal.usda.gov/fdc-app.html#/food-details/174673/nutrients 
  3. Hung WL, Suh JH, Wang Y. Chemistry and health effects of furanocoumarins in grapefruit. Journal of Food and Drug Analysis. 2017 Jan 1;25(1):71–83. Available from: https://www.sciencedirect.com/science/article/pii/S1021949816301843 
  4. Fujioka K, Greenway F, Sheard J, Ying Y. The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome. J Med Food [Internet]. 2006 Mar [cited 2022 Jun 26];9(1):49–54. Available from: https://pubmed.ncbi.nlm.nih.gov/16579728/ 
  5. Castro-Vazquez L, Alañón ME, Rodríguez-Robledo V, Pérez-Coello MS, Hermosín-Gutierrez I, Díaz-Maroto MC, et al. Bioactive Flavonoids, Antioxidant Behaviour, and Cytoprotective Effects of Dried Grapefruit Peels (Citrus paradisi Macf.). Oxidative Medicine and Cellular Longevity [Internet]. 2016 [cited 2022 Jun 26];2016. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745316/
  6. Fujioka K, Greenway F, Sheard J, Ying Y. The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome. J Med Food. 2006 Spring;9(1):49-54. doi: 10.1089/jmf.2006.9.49. PMID: 16579728. Available from: https://pubmed.ncbi.nlm.nih.gov/16579728/
  7. Dow CA, Going SB, Chow HH, Patil BS, Thomson CA. The effects of daily consumption of grapefruit on body weight, lipids, and blood pressure in healthy, overweight adults. Metabolism. 2012 Jul;61(7):1026-35. doi: 10.1016/j.metabol.2011.12.004. Epub 2012 Feb 2. PMID: 22304836. Available from: https://pubmed.ncbi.nlm.nih.gov/22304836/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Green Apple: Uses, Benefits, Side Effects and More!

Introduction

The green apple is a hybrid fruit. It is developed by combining two different species of apple, namely, Malus slyvesterus and Malus domesticus. It contains bioactive compounds and flavonoids in a very good amount as compared to other varieties of apples. Green apples were first cultivated by an Australian woman named Maria Smith; hence, they are also known as Granny Smith apples1.

This fruit appears light green with tart, juicy and crisp flavours and hard skin with a long shelf-life as compared with other apple types. Green apples are considered a healthy fruit and are used in weight management regimens due to their low calorie content and high dietary potassium and fibre content1

Nutritional Value of Green Apple (per 100g)

Green apple has a very high amount of nutrients2

Macronutrient Composition

Vitamin and Mineral Content

Properties of Green Apple

Apples are considered traditional fruits and consumed due to their nutritional properties, which are contributed by their bioactive compounds and dietary fibres3. The beneficial properties of green apples includes: 

Potential Uses of Green Apple

For many years, the traditional systems of medicine have been using apples in the management of various conditions3. Some of the potential uses of the green apple can be described as follows. 

1. For Cancer  

The green apple is rich in flavonoids that may help to reduce the risk of developing lung, pancreatic and colon cancer. Studies3 have also shown that green apples may have the potential to help with the growth of cancer cells in the breast, colon and skin. In clinical studies4, it has been shown that both males and females who consumed green apples in their diet had a reduced risk of developing lung cancer. However, cancer is a serious condition and would need a specialised doctor to diagnose and decide on treatment. It is important that you consult your healthcare provider before proceeding with any herbal remedy for health conditions.    

2. For Brain  

The extract of green apple juice may help prevent damage to the brain. An animal study5 showed that the animals fed with a green apple diet had increased levels of neurotransmitters, which act as signalling molecules of the brain. Research has confirmed that eating green apples, which are a high-fibre food, may help fight against brain diseases. Green apples also help in preventing the symptoms of Alzheimer’s and Parkinson’s diseases3. If you are suffering from any conditions or observe any symptoms related to brain function, make sure you talk to your healthcare provider about the risks and benefits of any herbal remedies.  

In my experience, consuming green apple juice, which is a potential source of Vitamin K, might have a positive impact on wound healing and repair. Vitamin K plays a crucial role in blood clotting and coagulation, which are essential processes for proper wound healing7.

Dr. Smita Barode, B.A.M.S, M.S.

3. For Asthma  

Consumption of green apples has been associated with managing many lung issues, including asthma. It has been shown that the intake of green apples reduces the incidence of asthma. A recent study6 in Australia showed that green apple intake decreases the risk of asthma and lung hypersensitivity. Another study with middle-aged men also showed a beneficial effect of apple consumption on lung functioning6. Asthma is a serious medical condition that requires you to follow your doctor’s advice and adhere to your treatment plan. It is advised that you consult your doctor before using green apples for its benefits for asthma.  

4. For Diabetes  

Eating apples daily may help overcome the risk of developing type 2 diabetes. Apples are full of soluble fibre and may play a key role in reducing blood sugar levels. A primary bioactive compound present in apple peels may also help to decrease the risk of diabetes. In clinical studies, it has been observed that consuming at least one green apple a day helps lower the risk of type 2 diabetes3. If you are suffering from diabetes, make sure you consult your doctor before making any changes to your diet.    

5. For Weight Management  

Doctors often recommend a high-fibre diet to improve and manage overall health. Apples are considered to be a high fibre food. Green apple has a high amount of dietary fibre, which is helpful for losing weight3. In a human study3, it has been shown that the consumption of green apples is associated with weight loss in middle-aged obese women. In a study4, people who consumed this fruit showed weight loss with reduced levels of blood glucose. If you want to lose weight, you can consult your doctor or nutritionist as they can guide you better about diet changes. Also, it is advised that you avoid making any major changes to your diet before consulting your doctor.  

6. Other Potential Uses of Green Apple  

Based on my experience, I have observed that consuming green apple juice might have positive effects on vision. The presence of Vitamin A in the juice has been known to support and improve eyesight. Incorporating green apple juice into your routine may help enhance your vision and contribute to overall eye health7.

Dr. Rajeev Singh, BAMS

How to Use Green Apple

Green apple can be used in the following ways: 

You should always consult your Ayurvedic physician before consuming green apples for therapeutic use. They will be the best person to prescribe you the correct form and dosage as per your health condition. Also, do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Did you know that apples are not only delicious but also packed with beneficial phenolic compounds? In fact, they rank second in total concentration of these compounds among fruits. What’s even more interesting is that apples have the highest portion of free phenolics compared to other fruits, making them a great choice for promoting health and well-being7.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Side Effects of Green Apple

There are some side effects of green apples related to teeth. The green apple is acidic and can cause demineralisation of the different portions of the tooth. The excess consumption of green apples may cause dental erosion (a chemical process that causes loss of mineralised tooth substance)8. Therefore, if you experience any dental problems, you must immediately contact your dentist. They will inform you about the various factors that cause erosion of the tooth.5 

Natural herbs may have some allergic reactions and may react differently in different people. Always consult your doctor before including any fruit or vegetable in your diet for its benefits.  

Also Read: Mango (Aam): Uses, Benefits, Side Effects by Dr. Smita Barode

Precautions to Take with Green Apple

Green apple is generally considered to be safe if it is taken in the recommended dosages. However, general precautions have to be followed while consuming a green apple. 

You must never self medicate, even with natural fruits, vegetables and herbs. It is advisable to consult your Ayurvedic physician for best advice.  

Interactions with Other Drugs

In clinical studies, it was shown that there is an interaction of the juice of apples with warfarin. Due to excess consumption of green apple juice, there is increased blood thinning that may result in an emergency situation9. Always disclose the ongoing treatments to your doctor, so that he can tailor a suitable prescription as per your ongoing treatment and conditions.  

Also Read: Lemongrass: Uses, Benefits, Side Effects and More!

Conclusion

From digestion to supporting weight management and potentially helping with conditions like diabetes and asthma, green apples pack in a surprising amount of goodness for such a simple fruit. While they aren’t a cure or a substitute for treatment, including them as part of your daily diet may offer gentle, long-term health benefits. As always, it’s best to speak to your doctor before making any dietary changes, especially if you’re managing a health condition.

Frequently Asked Questions (FAQs)

Which vitamins are present in a green apple?  

Green apple contains vitamin A, vitamin B3, vitamin E, vitamin B1, folate (vitamin B9), vitamin B6, vitamin B2 and vitamin K. 

Do green apples help with irritable bowel syndrome?  

Yes, green apples are rich in soluble dietary fibres that are used in the management of irritable bowel syndrome, which is a digestive system disorder that causes stomach cramps, stomach pain, constipation, diarrhoea, etc. Doctors also recommend green apples on a regular basis to prevent irritable bowel syndrome3.If you are suffering from irritable bowel syndrome or any other condition of the digestive tract, make sure you adhere to your doctor’s advice and make diet changes accordingly.  

What is pectin?  

All varieties of apples contain a soluble fibre known as pectin. It is a viscous, soluble and fermentable fibre that contributes to the beneficial properties of apples3.

What is the role of vitamin C in green apples?  

Vitamin C shows potent antioxidant activity. It also helps in fighting cancers of the lung and colon4

What are the advantages of green apples for oral health?  

If you bite and chew a green apple, it stimulates the production of saliva in the mouth and helps in reducing tooth decay by lowering the levels of bacteria in the mouth3.

Are green apples good for your cholesterol?  

Yes, green apples are good for health. The soluble fibre of apples binds with fats in the intestine, which results in lower cholesterol levels and helps you to remain healthier3.If you are suffering from high cholesterol, contact your doctor or healthcare provider before using green apples or any herb as a remedy. They can help you make better and well-informed choices as per your condition.  

References

  1. Veena G, Challa SR, Palatheeya S, Prudhivi R, Kadari A. Granny Smith Apple Extract Lowers Inflammation and Improves Antioxidant Status in L-arginine-induced Exocrine Pancreatic Dysfunction in Rats. Turk J Pharm Sci. 2021 May 30;18(3):262-70. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231327/pdf/TJPS-18-262.pdf
  2. Ahmad S, Mahmood T, Kumar R, Bagga P, Ahsan F, Shamim A, et al. A contrastive phytopharmacological analysis of gala and fuji apple. Res J Pharm Tech. 2020 Jun 15;13(3):1527-37. Available from: https://rjptonline.org/HTML_Papers/Research%20Journal%20of%20Pharmacy%20and%20Technology__PID__2020-13-3-83.html 
  3. Boyer J, Liu RH. Apple phytochemicals and their health benefits. Nutr J. 2004 May 12;3:5. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442131/pdf/1475-2891-3-5.pdf
  4. Boyer J, Liu RH. Apple phytochemicals and their health benefits. Nutrition Journal. 2004 [cited 2025 Jun 30]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC442131/
  5. Research shows benefits of apple juice on neurotransmitter affecting memory [Internet]. ScienceDaily. 2006 [cited 2025 Jun 30]. Available from: https://www.sciencedaily.com/releases/2006/08/060801225922.htm 
  6. Boyer J, Liu RH. Apple phytochemicals and their health benefits. Nutrition Journal. 2004 [cited 2025 Jun 30]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC442131/ 
  7. S S, Shabaraya AR. A review on pharmacological activities of (hybrid percentage) – Malus domestica M. sylvestris (green apple). ResearchGate. 2019 [cited 2025 Jun 30]. Available from: https://www.researchgate.net/publication/332979875_A_REVIEW_ON_PHARMACOLOGICAL_ACTIVITIES_OF_HYBRID_PERENTAGE_-_MALUS_DOMESTICA_M_SYLVESTRIS_GREEN_APPLE 
  8. Al Anazi EZ. Dental erosion caused by Granny Smith apples: An evidence”based case report and 1”year follow”up. Clin Case Rep. 2018 June 12;6(1):1689-96. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132154/pdf/CCR3-6-1689.pdf
  9. Choi M, Mintz M, Bates D. Interaction between Warfarin and Apple Juice. Canadian J Hosp Pharm. 2016 Feb 15;69(1):42-4. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777580/pdf/cjhp-69-42.pdf 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Plums (Aloo Bukhara): Uses, Benefits, Side Effects & More!

Introduction

Plum (Prunus domestica L.) belongs to the Rosaceae family and includes approximately 40 different species. It is a small, shrubby, deciduous tree that typically grows between 6 and 15 metres in height. Plums are widely cultivated across tropical and temperate regions, including parts of West Asia, India, Australia, South America, Pakistan, Europe, and Africa. In India, plums are primarily grown in the states of Uttarakhand, Himachal Pradesh, Jammu & Kashmir, and Punjab1.  

The plum tree is used for its beneficial properties and for managing various conditions. The fruits of the plum come in various colours, including, green, red, purple, and yellow and and are typically round in shape. It is rich in antioxidants, polyphenols, and carotenoid compounds. The Santa Rosa, Black Amber, Red Beauty, African Rose and Black Beauty are some major varieties of plum fruit1,3.  

Nutritional Value of Plum

The nutritional value of plum per 100 gm is given as follows2:  

Properties Of Plum

Plum is regarded in traditional practices as a plant with potential wellness-supporting properties. Research1 and preliminary studies suggest that it may exhibit certain biological activities. These include: 

Potential Uses of Plum

Plums are not just delicious seasonal fruits but are also known for their potential nutritional and wellness-supporting properties. Traditionally, they have been used in various cultures as part of a balanced diet to support general health and wellbeing1.  

1. Potential Uses of Plum for Diabetes

Diabetes is a metabolic condition that occurs when the body produces insufficient insulin or is unable to use it effectively. Preliminary animal studies have explored the potential effects of plum extracts on blood glucose levels. In these studies11, plum extract was associated with a reduction in blood sugar levels in diabetic rats. Additionally, some findings suggest that plum purée may have a role in moderating post-meal blood glucose spikes in experimental settings.    

Foods with a low glycaemic (glucose) index (GI) are digested more slowly and may help to support stable blood sugar and insulin levels after meals. As such, they are often recommended as part of a balanced diet for individuals managing blood glucose levels. In a small human study12, consumption of dried plums while fasting was associated with a reduction in insulin and plasma glucose levels3,4

While these findings are promising, more research is needed. Individuals with diabetes should consult a qualified healthcare professional before incorporating dried plums or any new food items into their diet, particularly when managing a medical condition. 

2. Potential Uses of Plum for Constipation

Plums, particularly in their dried form, have traditionally been used to support digestive health. They are a source of dietary fibre, sorbitol, and isatin, compounds which may contribute to maintaining regular bowel movements. Some studies4 suggest that dried plums could help in softening stools and promoting gut motility, potentially offering relief in cases of occasional constipation.  

In addition, plums contain phenolic compounds and serotonin, which may support intestinal function, as well as prebiotic properties that help maintain a healthy balance of gut bacteria. However, individuals experiencing digestive discomfort or diagnosed conditions such as irritable bowel syndrome should consult a qualified healthcare professional before making any dietary changes or using plums for symptom management3.  

3. Potential Uses of Plum for Cancer

Laboratory studies have suggested that plum extracts may exhibit antioxidant activity, particularly in the flesh, peel, and pit of the fruit, where antioxidant levels are reported to be highest. Some experimental research5 has explored the potential of these antioxidants to interact with cellular pathways, including those involved in cancer cell resistance. However, these observations are based on preliminary findings in laboratory settings and have not been confirmed in human clinical trials. 

While plums are a natural source of vitamin A, which supports general immune and cellular health, there is currently no conclusive evidence to suggest that consuming plums can prevent or treat cancer. Individuals should not use plums or any other natural product as a substitute for professional medical advice or treatment. 

4. Potential Uses of Plum for Bones

Plum contains vitamin K, copper, potassium and boron. Vitamin K may help with the mineralisation of bone and potassium helps to maintain bone mineral density. The alcohol extracts of plum have been shown to inhibit the resorption of bone and increase the formation of bone during a lab trial4.  

In animal studies6, it has been shown that plum was very effective on the pre-existing loss of bone. The powder of plum resulted in an increased bone mineral density and restored the vertebrae (spine) of rats. These benefits have been proven in animal studies and are yet to be observed in human trials. Therefore, avoid using plums for any disease condition of bones without consulting your healthcare provider.  

In addition to being delicious and nutritious, plums are known to aid in bone quality improvement. They are a great source of vitamin K, which is essential for bone health, as vitamin K helps in the absorption of calcium14.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

5. Potential Uses of Plum for Pregnancy

Animal studies4 have noted that oral administration of extract of plum in pregnant animals resulted in increased development and formation of bone (osteogenesis) in the baby. The extract of plum also helps increase the amount of serum calcium, resulting in a higher ratio of new bone formation compared to the existing length of a long bone. The benefits have been observed in animal studies, and are yet to be confirmed in humans. You need to exercise precautions before using plums during pregnancy.     

6. Potential Uses of Plum for Weight Loss

Plum contains polyphenols and bioactive compounds,that have been studied for their potential role in energy metabolism. Some preliminary research4 suggests that these compounds may influence appetite regulation and support metabolic functions. Plum juice is relatively low in calories, and when consumed as part of a balanced, calorie-controlled diet, it may contribute to maintaining a healthy weight.  

In a preclinical study7, the consumption of plum juice was useful for the loss of body weight. The low calories in plum juice and higher content of polyphenols may also help to reduce body weight.  

7. Other Health Benefits of Plum

Although some studies have suggested potential health benefits of plum juice (and beetroot juice) in various conditions, the current evidence is limited. Further well-designed clinical research is required to establish the extent and reliability of these effects in humans. 

Plums contain naturally occurring compounds that have been studied for their antioxidant and anti-inflammatory properties. Preliminary research suggests these properties may help support overall brain health by protecting cells from oxidative stress14.

Dr. Rajeev Singh, BAMS

How to Use Plum

Plum can be used in the following ways:  

You should always consult your Ayurvedic physician before consuming plums for regular use. They will be the best person to prescribe you the correct form and dosage as per your health condition. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.

Also Read: Blueberries: Uses, Benefits, Side Effects, and More!

Side Effects of Plum

While plums are generally safe when consumed in moderation as part of a balanced diet, some individuals may experience side effects. These are mostly related to digestive sensitivity or allergic reactions. Commonly reported effects include: 

However, if you experience any adverse reactions to plum, immediately contact your Ayurvedic physician who has prescribed it to you. They will be able to treat you appropriately. 

Plums are a rich source of natural antioxidants and essential nutrients, which may help protect the body’s cells from oxidative stress, a factor associated with the natural ageing process. Including antioxidant-rich fruits like plums as part of a balanced diet may contribute to overall skin and cellular health1.

Dr. Smita Barode, BAMS, M.S.

Precautions to Take with Plum

Plum is generally considered to be safe for most individuals when consumed in moderation as part of a balanced diet. However, certain precautions should be observed: 

Also Read: Chirata: Benefits, Side Effects, Precautions and More!

Interactions with Other Drugs

Various fruit juices contain an unknown amount of phytochemicals and when combined with other medicines, they can lead to food–drug interactions resulting in side effects. Similarly, plum juice also has multiple phytochemicals that can lead to increased exposure to the system, resulting in high blood pressure (hypertension)10. This food–drug interaction needs to be considered by your Ayurvedic physician to avoid developing serious health issues. Therefore, follow the advice of your Ayurvedic physician who has prescribed you this supplement.   

Conclusion

Plums are nutrient-dense fruits with potential health benefits ranging from helping with digestion to supporting bone and heart health. Rich in antioxidants and essential vitamins, they may help in managing various conditions. However, further human studies are needed, and medical advice is essential before therapeutic use.

Also Read: Papaya (Papita): Uses, Benefits, Side Effects and More!

Frequently Asked Questions (FAQs)

Is plum good for diabetes?   

Yes, plums have a low glycaemic index and also contains sorbitol which helps in lowering the levels of glucose in the blood.  If you or someone you know has diabetes, avoid using any herb or fruit without consulting your healthcare provider.   

What are the different advantages of plum?   

Plum fruit contains nutrients and antioxidants that may support overall health, including immune function and eye health. Some laboratory and animal studies have explored its potential role in managing conditions such as arthritis, asthma, anaemia, elevated cholesterol, and cognitive decline. However, more robust clinical research is needed to confirm these effects in humans.  However, avoid using plum for any health condition without consulting with a doctor first.   

What vitamins are present in plum and what are the benefits?   

Plum contains vitamin A, vitamin B, vitamin C, vitamin K and vitamin E.
Vitamin A protects against oral and lung cancers. Vitamin B helps to metabolise carbohydrates, proteins, and fats in the body. Vitamin C contributes to the body’s natural defence mechanisms and acts as an antioxidant by neutralising free radicals. Vitamin K plays a vital role in blood clotting and is important for bone metabolism. Some studies have also investigated its potential association with cognitive health in older adults. 

Is plum good for weight loss?   

Yes, studies13 have shown that replacing sugary drinks with polyphenol-rich juices like plum juice may support weight management and help prevent obesity. However, it is important to consult your healthcare provider or nutritionist before making any significant changes to your diet, as these changes can affect your overall health. 

Can we use plum as mosquito repellent? 

Yes, the extract has demonstrated activity against mosquito larvae and may be used as a natural mosquito repellent when applied to the skin. 

What are the benefits of plum skin?   

Plum skin contains a high amount of phenolic compounds, which exhibit strong antioxidant activity. These antioxidants may help in preventing the spread of cancer cells. However, for any serious medical condition, it is essential to consult a qualified doctor.  

References

  1. Shukla RK, Kishan. A Review on European Plum (Prunus domestica) for its Pharmacological Activities and Phytochemicals. Res J Pharm Tech. 2021 Feb 1;14(2). Available from: https://rjptonline.org/AbstractView.aspx?PID=2021-14-2-103  
  2. United States Department of Agriculture [Internet]. Plums, raw; 2019 Apr 1 [cited 2022 June 2]. Available from https://fdc.nal.usda.gov/fdc-app.html#/food-details/169949/nutrients  
  3. Stacewicz-Sapuntzakis M. Dried Plums and Their Products: Composition and Health Effects-An Updated Review. Crit Rev Food Sci Nutr. 2013 Oct 3;53(12):1277-302. Available from: https://doi.org/10.1080/10408398.2011.563880  
  4. Igwe EO, Charlton KE. A Systematic Review on the Health Effects of Plums (Prunus domestica and Prunus salicina). Phytother Res. 2016 Mar 1;1:5581. Available from: https://www.researchgate.net/profile/Ezinne-Igwe/publication/298899398_A_Systematic_Review_on_the_Health_Effects_of_Plums_Prunus_domestica_and_Prunus_salicina/links/59e936adaca272bc4278504c/A-Systematic-Review-on-the-Health-Effects-of-Plums-Prunus-domestica-and-Prunus-salicina.pdf   
  5. Bahrin AA, Moshawih S, Dhaliwal JS, Kanakal MM, Khan A, Lee KS, et al. Cancer protective effects of plums: A systematic review. Biomed Pharmacother. 2021 Dec 25;146:1-17. Available from: https://doi.org/10.1016/j.biopha.2021.112568  
  6. Graef JL, Ouyang P, Wang Y, Rendina-Ruedy E, Lerner MR, Marlow D, et al. Dried plum polyphenolic extract combined with vitamin K and potassium restores trabecular and cortical bone in osteopenic model of postmenopausal bone loss. Journal of Functional Foods [Internet]. 2018 Mar [cited 2025 May 27];42:262–70. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6176741/  
  7. Noratto G, Martino HSD, Simbo S, Byrne D, Mertens-Talcott SU. Consumption of polyphenol-rich peach and plum juice prevents risk factors for obesity-related metabolic disorders and cardiovascular disease in Zucker rats. J Nutr Biochem. 2015 Jun 1;26(6):633-41. Available from: https://sci-hub.hkvisa.net/10.1016/j.jnutbio.2014.12.014 
  8. Birwal P, Deshmukh G, Saurabh SP, Pragati S. Plums: A Brief Introduction. J Food Nutr Popul Health. 2017 Mar 16;1(1):8. Available from: https://www.researchgate.net/profile/Pragati-Singham/publication/316476857_Plums_A_brief_introduction/links/5a9e65a40f7e9bc35fd01e88/Plums-A-brief-introduction.pdf  
  9. Pastorello EA, Ortolani C, Farioli L, Pravettoni V, Ispano M, Borga A, et al. Allergenic cross-reactivity among peach, apricot, plum, and cherry in patients with oral allergy syndrome: An in vivo and in vitro study. J Allergy Clin Immunol.1994 Oct 20;1:699-707. Available from: https://www.jacionline.org/article/0091-6749(94)90177-5/pdf  
  10. Petric Z, Žuntar I, Putnik P, KovaÄević DB. Food–Drug Interactions with Fruit Juices. Foods. 2020 Dec 24;10(1):33. Available from: https://www.mdpi.com/2304-8158/10/1/33/htm  
  11. Utsunomiya H, Yamakawa T, Kamei J, Kadonosono K, Tanaka S. Anti-hyperglycemic effects of plum in a rat model of obesity and type 2 diabetes, Wistar fatty rat. Biomed Res. 2005 Oct;26(5):193-200. doi: 10.2220/biomedres.. 26.193. PMID: 16295695. Available from: https://pubmed.ncbi.nlm.nih.gov/16295695/
  12. Damani JJ, Rogers CJ, Lee H, Strock NC, Koltun KJ, Williams NI, Weaver C, Ferruzzi MG, Nakatsu CH, De Souza MJ. Effects of prune (dried plum) supplementation on cardiometabolic health in postmenopausal women: an ancillary analysis of a 12‑month randomized controlled trial, The Prune Study. J Nutr. 2024 May;154(5):1604–18. doi: 10.1016/j.tjnut.2024.03.012. Epub 2024 Mar 13. PMID: 38490532; PMCID: PMC11347804. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347804/
  13. Noratto GD, Martino HS, Simbo S, Byrne D, Mertens‑Talcott SU. Consumption of polyphenol-rich peach and plum juice prevents risk factors for obesity-related metabolic disorders and cardiovascular disease in Zucker rats. J Nutr Biochem. 2015 Jun;26(6):633–41. doi:10.1016/j.jnutbio.2014.12.014. PMID:25801980. Available from: https://pubmed.ncbi.nlm.nih.gov/25801980
  14. Wallace TC. Dried Plums, Prunes and Bone Health: A Comprehensive Review. Nutrients. 2017 Apr 19;9(4):401. doi: 10.3390/nu9040401. PMID: 28422064; PMCID: PMC5409740. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5409740/
  15. Keservani RK, Sharma AK, Kesharwani RK. Medicinal effect of nutraceutical fruits for the cognition and brain health. Scientifica (Cairo). 2016;2016:3109254. doi: 10.1155/2016/3109254. PMID: 26966612; PMCID: PMC4757744. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757744/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof. 

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Munakka: Benefits, Side Effects, Precautions and More!

Introduction

Munakka, also called black grape raisins in English, is a fruit with immense value due to its several potential benefits. The leaves, seed, skin of Munakka and the whole fruit contain helpful properties. Munakka is effective in balancing Vata and pitta doshas in the body. Dry grapes or Munakka are packed with nutrients and calories. Munakka (raisins) are initially green in color and darken as they are dried, resulting in a dried, dark-colored fruit having small seeds1

Nutritional Value of Munakka

Munakka is rich in sugars (glucose and fructose), vitamins (ascorbic acid, riboflavin, thiamin, pyridoxine), dietary fibers, and minerals (zinc, phosphorous, iron, magnesium, calcium, potassium). Munakka also contains different types of phytochemicals (plant-derived compounds) like flavonoids, resveratrol, epicatechins, phytoestrogens, and hydrocinnamic acids2. In 100 grams, the below are the nutrients found in munakka3:

I came across a study that shows some awesome anti-ageing wonders of munakka. Compounds called polyphenolics found in foods like munakka might help reverse the effects of ageing on the brain and behaviour. These compounds are like superheroes with antioxidant powers, protecting the organs and tissues from damage caused by oxidative stress. However, studies on humans are needed to validate these claims21.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Munakka

Munakka may show a variety of properties such as4

Potential Uses of Munakka

Due to its beneficial properties, munakka may have potential use in several health conditions such as:

1. Potential Uses of Munakka for Gastrointestinal Health

stomach

Munakka contains dietary fiber which helps absorb natural fluids in the body. This adds volume to the food moving down the intestinal tract this may result in regular bowel movements and relief from constipation. The fibers may also help in eliminating harmful toxins from the body3

Munakka might also be beneficial in improving colon function. Munakka might also have some effect on reducing the risk of colorectal cancer.  However, there is a need for further research on humans to suggest the potential uses of Munakka that might benefit in these conditions.

I would recommend munakka for proper digestion and colon health. It was observed that eating raisins may have some positive effects on our digestion and colon health. It might make digested food move through the intestines faster. What’s even cooler is that the levels of bile acids in the faeces, which may be a sign of colon cancer risk, reduced22.

Dr. Rajeev Singh, BAMS

2. Potential Uses of Munakka for Anemia

blood toxicity

Due to its iron content, munakka could help in anemia. Munakka might also contain vitamin B complex which is required for producing red blood cells5. This information is insufficient; hence more research is required to study the effects of Munakka in managing blood related problems in humans. You must consult your doctor for better advice.

3. Potential Uses of Munakka for Dental Health

dental issues

Munakka contains calcium which might help strengthen and remineralize tooth enamel. They might help decrease dental decay. This is due to certain compounds present in munakka that help inhibit oral pathogens. The anti-oxidant nature of munakka can help in eliminating bacteria that are responsible for dental caries and cavities. Munakka also contains antibacterial properties that help prevent dental caries6. Since there are insufficient studies to establish this claim, you must consult a dentist for oral health.

4. Potential Uses of Munakka for Bone Health

strengthen bones

Calcium is the main constituent of bones and is present in munakka. Boron is also a nutrient that is essential for proper bone formation and enhanced calcium absorption. Munakka also contains potassium which may help enhance bone growth, thus potassium, boron and calcium present in munakka, might be helpful in osteoporosis in women5,7. Consult an Ayurvedic doctor before using ginger and only use it if prescribed.

5. Potential Uses of Munakka for Skin

moisturizing skin

Munakka contains vitamin C and antioxidants that might help to maintain glowing and healthy skin. It also contains antioxidant properties that are helpful in bacterial infections and may also prevent psoriasis and acne8. A dermatologist will be able to guide you better for skin conditions.

6. Potential Uses of Munakka for Hair

Having munakka daily can help you have a head full of lustrous, thick hair due to its vitamin C content. Munakka may also contain anti-inflammatory properties that might be effective against dandruff and irritation9. You can consider to consult a doctor before using it.

7. Potential Uses of Munakka for the Heart

Munakka may help lower blood pressure and blood sugar levels resulting in a lower risk of heart disease. The fiber content in munakka might reduce low density or bad cholesterol. Low potassium levels in the body may cause high blood pressure, stroke, and heart disease. Munakka is a good source of potassium and can help improve heart health and prevent these heart conditions10,11. However, any heart condition can be serious and must be properly diagnosed and treated by a doctor.

8. Potential Uses of Munakka for Weight Loss

weight loss

Due to its composition, munakka ensures a better diet quality, and having it before a meal could help regulate appetite in healthy individuals who have an average weight.  Munakka might modulate hormones influencing satiety resulting in reduced hunger and dietary intake which can be useful to maintain a healthy body mass12. However, more research is required to prove such claims. You must contact a nutritionist for advice.

9. Other Potential Uses of Munakka

munakka

Though there are studies that show the potential uses of dhania in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of dhania on human health.  

How to Use Munakka

Munakka is available in three forms16

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Also Read: Phalsa fruit (Grewia asiatica): Uses, Benefits, and Side Effects By Dr. Smita Barode 

Side Effects of Munakka

When taken in large amounts, munakka can result in side effects due to its rich nutrient content17.  

Herbs may react differently with everyone we must exercise caution while using munakka.

Also Read: Neem: Uses, Benefits, Side Effects, and More!

Precautions to be Taken with Munakka

Also Read: Camphor: Uses, Benefits, Precautions, Side Effects & More!

Frequently Asked Questions (FAQs)

Is Munakka and Kishmish the Same? 

Munakka and kishmish contain different nutritional values. Kishmish is yellow in color and Munakka is brown in color. Kishmish does not contain any seeds while Munakka has seeds19.  

Can Munakka be Used for Acidity? 

A diet low in potassium and magnesium might result in acidity. Munakka is a great source of magnesium and potassium. Hence, adding Munakka to your daily diet might help prevent acidity1. However, more research is required to confirm such potential effects of munakka.

Can Munakka be used to boost energy? 

Munakka contains a lot of amino acids, vitamins, and minerals like phosphorous which might help in the uptake of other nutrients in the body. Hence, adding Munakka to your diet could enhance your energy and boost your immunity18. More research is needed to validate this fact.

Can Munakka be used for restoring liver function? 

Munakka contains liver protective and regenerative properties. This may be due to its phenolic content20. However, more research is required to confirm such potential effects and consult a doctor for better advice.

How many raisins can you consume in a day? 

The ideal portion of raisins that can be taken for a healthy, balanced like is 40g. This can protect you from type 2 diabetes, hypertension, and cardiovascular diseases21

When can babies start eating Munakka? 

Babies can start having Munakka after 18 months. Munakka and other dried fruits are a choking hazard for babies below 12 months of age. It is best to consult a doctor before introducing anything into children’s diet22.

Can Munakka be used for cough? 

Yes, Munakka could help treat cough due to its cough suppressant activity. It might also help relieve any irritation in the throat. However, more research is required to confirm such potential effects of munakka.

References

  1. Journal of nutrition and health. A comprehensive review of raisins and raisin components and their relationship to human health. [Internet] Available from: https://www.koreascience.or.kr/article/JAKO201720861241372.page 
  1. National center for biotechnology information. Association of raisin consumption with nutrient intake, diet quality, and health risk factors in US adults: National health and nutrition examination survey 2001-2012 [Internet] Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642187/#:~:text=Raisins%20are%20low%E2%80%93medium%20energy,0.8%20mg%20iron%20%5B5%5D 
  1. National centre for biotechnology information. Is eating raisins healthy? [Internet] Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019280/ 
  1. Journal of pharmaceutical research international. Black raisins improved experimentally induced iron deficiency anemia. Biochemical and histological evidence. [Internet] Available from: https://www.journaljpri.com/index.php/JPRI/article/view/31839 
  1. Science direct. Antimicrobial constituents of thompson seedless raisins (vitis vinifera) against selected oral pathogens. [Internet] Available from: https://www.sciencedirect.com/science/article/abs/pii/S1874390008000542 
  1. National center for biotechnology information. The association of potassium intake with bone mineral density and the prevalence of osteoporosis among older Korean adults. [Internet] Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997142/ 
  1. National center for biotechnology information. Vitamin C in dermatology. [Internet] Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673383/ 
  1. Research gate. The role of vitamins and minerals in hair loss: A review. [Internet] Available from: https://www.researchgate.net/publication/329628006_The_Role_of_Vitamins_and_Minerals_in_Hair_Loss_A_Review 
  1. National institutes of health. How too little potassium may contribute to cardiovascular disease. [Internet] Available from: https://www.nih.gov/news-events/nih-research-matters/how-too-little-potassium-may-contribute-cardiovascular-disease 
  1. American college of Cardiology. Snacking on raisins may offer a heart-healthy way to lower blood pressure. [Internet] Available from: https://www.acc.org/about-acc/press-releases/2012/03/25/15/51/raisins_bp 
  1. 39th World congress of vine and wine. Raisins in human health: a review. [Internet] Available from: https://www.bio-conferences.org/articles/bioconf/pdf/2016/02/bioconf-oiv2016_04005.pdf 
  1. DNGO care. Munakka for piles: Effective home remedy for hemorrhoids. [Internet] Available from: https://dengo.in/munakka-for-piles-effective-home-remedy-for-hemorrhoids/ 
  1. Organic facts. Raisins: Benefits, side effects and how to eat [Internet] Available from: https://www.organicfacts.net/health-benefits/fruit/health-benefits-of-raisins.html 
  1. Planet Ayurveda. Grapes (vitis vinifera)- Properties, benefits, uses, dosage. [Internet] Available from: https://www.planetayurveda.com/library/grapes-vitis-vinifera/ 
  1. Prajna Paramita Panda, Dr. Shiva Kumar Harti and Dr. Mangalagowri V. Rao; Analytical study on grapes and its therapeutic uses. European journal of biomedical and pharmaceutical sciences. 2018 5 (4): 150-154 Available from: https://storage.googleapis.com/journal-uploads/ejbps/article_issue/volume_5_april_issue_4/1522484418.pdf 
  1. Pub med. Progressive motility increase caused by L-arginine and polyamines in sperm from patients with idiopathic and diabetic asthenozoospermia. [Internet] Available from: https://pubmed.ncbi.nlm.nih.gov/14515660/ 
  1. Research gate. Raisins: A kitchen cabinet item that can restore the liver function and structure. [Internet] Available from: https://www.researchgate.net/publication/343821161_Raisins_A_kitchen_cabinet_item_can_restores_the_liver_function_and_structure 
  1. The New England Journal of medicine. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. [Internet] Available from: https://www.nejm.org/doi/full/10.1056/nejm200005113421903 
  1. Centers for disease control and prevention. Choking hazards. [Internet] Available from: https://www.cdc.gov/nutrition/infantandtoddlernutrition/foods-and-drinks/choking-hazards.html 
  1. Shahnaz Sultana, Andleeb Khan, Mohammed M Safhi And Hassan A.Alhazmi; Cough suppressant herbal drugs: a review. International journal of pharmaceutical science invention. 2016 Aug 5(5): 2319-6718 Available from: http://www.ijpsi.org/Papers/Vol5(5)/D0505015028.pdf 
  2. Xia EQ, Deng GF, Guo YJ, Li HB. Biological activities of polyphenols from grapes. Int J Mol Sci. 2010 Feb 4;11(2):622-46. doi: 10.3390/ijms11020622. PMID: 20386657; PMCID: PMC2852857. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC2852857/
  3. Olmo-Cunillera A, Escobar-Avello D, Pérez AJ, Marhuenda-Muñoz M, Lamuela-Raventós RM, Vallverdú-Queralt A. Is Eating Raisins Healthy? Nutrients. 2019 Dec 24;12(1):54. doi: 10.3390/nu12010054. PMID: 31878160; PMCID: PMC7019280. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7019280/#B43-nutrients-12-00054

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