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Rambutan: Uses, Benefits, Side Effects, and More By Dr. Smita Barode

By Dr Smita Barode +2 more

Introduction

Rambutan is a fascinating looking red spiky fruit with soft thorns in red, yellow, and green shades. It is also known as a hairy fruit. It is a tropical, ovoid shaped fruit with a red or yellow fruit wall. The Rambutan tree is originally from Malaysia, and its name is derived from the Malay word ‘rambut’ which means hair. Rambutan is popularly grown in India, Malaysia, Indonesia, Thailand, and some humid parts of the United States. The scientific name of rambutan is Nephelium lappaceum, and it belongs to the family Sapindaceae. Rambutan pulp, seeds and peel have several bioactive compounds that may benefit food, pharmaceuticals, medicine, and cosmetics advances1. Let us glance through some of the benefits of eating rambutan and experience the unique rambutan taste, characterized by its sweet and juicy profile with hints of floral notes.

benefits of rambutan

Nutritional Value of Rambutan

Rambutan seeds, peel and pulp may contain several bioactive compounds like polyphenols, including ellagitannins, geraniin, corilagin, and ellagic acid. It may contain fatty acids like arachidonic acid, stearic acid, palmitic acid and many more1. Furthermore, Rambutan fruit may contain the following nutrients: 

  • Energy: 82 kcal 
  • Water: 78 g
  • Fats: 0.21 g 
  • Protein: 0.65 g 
  • Fibre: 0.9 g 
  • Carbohydrates: 20.9 g
  • Magnesium: 7 mg
  • Potassium: 42 mg 
  • Calcium: 22 mg
  • Phosphorous: 9 mg
  • Iron: 0.35 mg 
  • Manganese: 0.343 mg 
  • Copper: 0.066 mg
  • Sodium: 11 mg 
  • Zinc: 0.08 mg 
  • Vitamin A: 3 IU 
  • Vitamin B1 (thiamine): 0.013 mg 
  • Vitamin B2 (riboflavin): 0.022 mg 
  • Vitamin B3 (niacin): 1.35 mg 
  • Vitamin B5 (pantothenic acid): 0.018 mg 
  • Vitamin B6 (pyridoxine): 0.02 mg 
  • Vitamin B9 (folate): 8ug
  • Vitamin C (ascorbic acid): 4.9 mg 
  • Beta carotene: 2 µg 

Did you know?


Properties of Rambutan

Several studies have shown that rambutan may have the following properties: 

  • It may be an antioxidant 
  • It may act against microbial infections 
  • It may reduce inflammation 
  • It may reduce blood glucose levels 
  • It may act against cancer 
  • It may lower blood pressure 
  • It may relieve fever 
  • It may delete worms from the intestine1

Rambutan seeds are roasted and eaten as snacks in the Philippines. Munching on these seeds as a morning or evening snack not only satisfies your taste buds but also offers rambutan benefits for health and well-being14.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Benefits of Rambutan For Overall Health

Some of the potential rambutan benefits are: 

1. Potential Benefits of Rambutan as an Antioxidant

Rambutan

A study3 by Hernàndez et al. in 2017 showed that rambutan might be an antioxidant. The antioxidant potential of rambutan may be due to phytochemical compounds like phenols, flavonoids, corilagin, geraniin, and ellagic acid. These compounds may deactivate the free radicals (harmful molecules present in the body) and protect the body from various damages. 

2. Potential Benefits of Rambutan for Cancer

cancer

A study by Perumal et al. in 2020 showed that rambutan might act against breast, bone, cervical and liver cancer. The anticancer activity of rambutan may be due to bioactive compounds like flavonoids, alkaloids, tannins, terpenoids and other phenolic compounds like geraniin. Rambutan benefits may show apoptosis (kill the cancer cells) and inhibit their growth. However more studies are required to check if rambutan can be used against cancer. Cancer is a serious disease therefore, you must consult your doctor if you suspect cancer instead of self-medicating. 

3. Potential Benefits of Rambutan for Reducing Sugar Levels

regulates blood sugar

Rambutan is a delicious tropical fruit that might offer potential benefits for diabetes management. A study by Muhtadi et al. in 2016, conducted on rats, suggested that bioactive compounds found in rambutan, such as catechin, quercetin, polyphenols, geraniin, and tannins, could contribute to reducing blood sugar levels. These compounds may help inhibit glucose absorption by the cells and stimulate insulin secretion, potentially assisting in the maintenance of normal blood sugar levels. It’s important to note that this study was conducted on animals, and further research on humans is needed to confirm the potential rambutan benefits for diabetes. If you have diabetes it’s essential to monitor your blood sugar levels regularly and consult with your healthcare provider for appropriate guidance.


4. Potential Benefits of Rambutan for Dengue

mosquito

A study6 by Ahmad et al. in 2015 showed that geraniin in rambutan might have anti-viral activity and act against DENV-2 (dengue virus type-2). Geraniin may inhibit the attachment of the dengue virus to the body cells and may also interfere with a viral protein (E protein) to disrupt the infection process. However, further studies are required to check if rambutan may act against the dengue virus. Therefore you must immediately consult your doctor if you suspect any symptoms of dengue. 

5. Potential Benefits of Rambutan to Reduce Inflammation

reduces inflammation

A study7 by Chingsuwanrote et al. in 2015 showed that the polyphenols in rambutan might reduce inflammation. The polyphenols may inhibit the secretion of TNFα, an inflammatory cytokine (molecules in the body responsible for inflammation). However, more studies are required to check if rambutan has anti-inflammatory properties. 

6. Potential Benefits of Rambutan for Bacterial Infections

infection

A study8 by Phuong et al. in 2020 showed that bioactive compounds in rambutan, like tannins, corilagin, geraniins, and ellagic acid, may possess antibacterial activity. Various bioactive compounds have different ways of showing their antibacterial activity. Tannins may change the structure of the cell wall and cell membrane. Ellagic acid may attach to the cell wall and destabilize it. Corilagin may inhibit the growth of bacteria by disrupting cell permeability. However, more large scale studies are required to check the antibacterial effect of rambutan. Therefore you must consult your doctor if you suspect a microbial infection. 

7. Potential Benefits of Rambutan for Controlling Blood Pressure

A study9 by Fang et al in 2018 suggested that rambutan fruit benefits might extend to lowering blood pressure. Specifically, geraniin found in rambutan may play a role in reducing blood pressure by decreasing the release of noradrenaline (a hormone that increases blood pressure) and relaxing tension in the blood vessels. Further research involving human subjects is needed to confirm these effects. It’s essential to consult your doctor if you have abnormal blood pressure instead of attempting self-medication.

Though studies show the benefits of rambutan in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of rambutan on human health. 

Researchers are evaluating the anti-HIV, anti-dengue and anti-allergic properties of Rambutan. These activities have been observed during lab trials more research is needed to support these claims14.

Dr. Rajeev Singh, BAMS

How to Use Rambutan?

Rambutan can be consumed in the following way: 

  • The fruit can be eaten fresh or canned. 
  • In addition, Rambutan fruit benefits in the preparation of fruit salads. 
  • Rambutan seeds can be roasted and eaten10.

You must consult a qualified doctor before taking large quantities of Rambutan or other herbal supplements. Likewise, do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor. 

Side Effects of Rambutan

Rambutan side effects are reported as follows: 

  • It may cause nausea and vomiting 
  • It may cause angioedema (swelling of the lower layer of skin) 
  • It may cause urticaria (swollen, reddened, and itchy skin) 
  • It may cause flushing of the skin (sudden redness of the skin) 
  • It may cause chest tightness and wheezing11 

If you notice any reaction by consuming rambutan, seek immediate medical attention. First, consult your ayurvedic physician who has prescribed it to you; they will be able to identify the cause and treat it. 

Precautions to Take with Rambutan

The following precautions can be taken before consuming rambutan: 

  • Rambutan is considered safe, but pregnant and breastfeeding mothers should take precautions before consuming rambutan12
  • Saponins and tannins are phytochemicals, and they are biologically active compounds. In a few cases, it may be toxic to a few people. The seeds of rambutan may be narcotic (causes sleepiness and affects mood)13

It is advised to consult your doctor before consuming if you have any pre-existing diseases. 

Conclusion

There is not enough evidence on the interaction of rambutan with other drugs. Further studies on the interaction of rambutan are required. Therefore you must consult your doctor if you are on any other medication before consuming rambutan. 

Frequently Asked Questions (FAQs)

What are Rambutan fruit side effects? 

Rambutan may cause nausea and vomiting, angioedema (swelling of the lower layer of skin), urticaria (swollen, reddened, and itchy skin), flushing of the skin (sudden redness of the skin), chest tightness, and wheezing11

Is Rambutan good for diabetes? 

Bioactive compounds in rambutan, like catechin, quercetin, polyphenols, geraniin, and tannins, may help to reduce blood sugar5. However, you must check your blood sugar levels regularly and consult your doctor in case of abnormal blood sugar levels

What precautions must be taken with Rambutan?

Rambutan is considered safe, but pregnant and breastfeeding mothers shall take precautions before consuming rambutan12. Saponins and tannins are phytochemicals, and they are biologically active compounds. But in a few cases, saponins and tannins may be toxic to a few people. In addition, rambutan seeds may be narcotic (causes sleepiness and affects mood)13. It is advised to consult your doctor if you have any pre-existing diseases before consuming. 

Can Rambutan seeds be eaten?

Rambutan seeds are generally not recommended for consumption as they can be bitter and potentially toxic. It’s advisable to consult with a healthcare professional for personalized guidance regarding your dietary choices and potential risks associated with consuming rambutan seeds.

Can Rambutan cause sore throat?

While rambutan consumption is not commonly associated with sore throat, individual reactions may vary. If you experience a sore throat after consuming rambutan or suspect any adverse reactions, it’s advisable to consult with a healthcare professional for a personalized assessment and guidance.

Can Rambutan make you sick?

Consuming rambutan is generally safe for most individuals. However, if you experience digestive discomfort, allergies, or any adverse reactions after consuming rambutan, it’s advisable to consult with a healthcare professional for a proper assessment and personalized guidance to determine the cause of the illness.

Can Rambutan increase uric acid?

Rambutan is not a known food source that significantly increases uric acid levels. However, individual reactions can vary, and those with gout or uric acid concerns should consume it in moderation and monitor their own body’s response. If you have specific health concerns, consulting a healthcare professional is advisable for personalized guidance.

Are Rambutans good for dogs?

Rambutan should be avoided for dogs as it can pose a choking hazard due to its large seed and may not provide significant nutritional benefits for them. It’s best to consult with a veterinarian for guidance on safe and appropriate treats for your pet.

Can Rambutan cause stomach pain?

Rambutan is typically safe to eat, but for some individuals, overconsumption or sensitivity to certain compounds in the fruit might lead to stomach discomfort or pain. If you experience stomach pain after consuming rambutan, consult a healthcare professional to rule out any allergies or sensitivities and to ensure it aligns with your dietary choices.

Can Rambutan cause constipation?

While rambutan is generally not associated with causing constipation, excessive consumption or dietary factors could potentially lead to this issue in some individuals. If you encounter constipation after eating rambutan, consult a healthcare professional to assess your dietary choices and address any underlying causes.

Can Rambutan cause acne?

Rambutan is not commonly linked to causing acne. However, an individual’s skin reactions can vary, and it’s possible that consuming rambutan, especially in excessive amounts, might lead to skin issues for some people. Consulting a healthcare professional or dermatologist can help identify any specific triggers and address potential skin concerns.

Can Rambutan cause cough?

Rambutan is not a known cause of cough. Coughing can result from various factors such as infections, allergies, or irritants. If you experience persistent coughing after consuming rambutan, consult a healthcare professional to rule out any allergies or underlying respiratory issues.

Can Rambutan cause miscarriage?

There is no scientific evidence to suggest that rambutan can cause a miscarriage. However, during pregnancy, it’s crucial to be cautious about your dietary choices and consult a healthcare professional for guidance on safe and healthy eating practices to support a healthy pregnancy.

Can Rambutan cause diarrhea?

Rambutan consumption is generally safe, but excessive intake may lead to diarrhea in some individuals due to its natural sugars and dietary fiber. If you experience persistent or severe diarrhea after eating rambutan, consult a healthcare professional to assess any underlying issues and ensure proper hydration and dietary choices.

How to eat Rambutan?

To eat rambutan, start by making a shallow cut around the circumference of the fruit’s skin, being careful not to cut too deep. Then, gently twist the fruit open, revealing the juicy flesh inside. Remove the seed and enjoy the sweet and slightly tangy fruit.

Is Rambutan a tree nut?

No, rambutan is not a tree nut. It is a tropical fruit belonging to the Sapindaceae family and is botanically related to lychee and longan. While it may trigger allergies in some individuals, it is not classified as a tree nut allergen.

References

  1. Hernández-Hernández C, Aguilar CN, Rodríguez-Herrera R, Flores-Gallegos AC, Morlett-Chávez J, Govea-Salas M, Ascacio-Valdés JA. Rambutan (Nephelium lappaceum L.): Nutritional and functional properties. Trends in food science & technology. 2019 Mar 1;85:201-10. Available from: https://www.researchgate.net/publication/391314241_Antiviral_Activity_of_Rambutan_Peel_Polyphenols_Obtained_Using_Green_Extraction_Technology_and_Solvents
  2. Rambutan, canned, syrup pack [Internet]. FoodData Central. [cited 2022Dec1]. Available from: https://fdc.nal.usda.gov/fdc-app.html#/food-details/168167/nutrients 
  3. Hernández C, Ascacio-Valdés J, De la Garza H, Wong-Paz J, Aguilar CN, Martínez-Ávila GC, Castro-López C, Aguilera-Carbó A. Polyphenolic content, in vitro antioxidant activity and chemical composition of extract from Nephelium lappaceum L.(Mexican rambutan) husk. Asian Pacific Journal of Tropical Medicine. 2017 Dec 1;10(12):1201-5. Available from: https://www.sciencedirect.com/science/article/pii/S1995764517311641 
  4. Perumal A, AlSalhi MS, Kanakarajan S, Devanesan S, Selvaraj R, Tamizhazhagan V. Phytochemical evaluation and anticancer activity of rambutan (Nephelium lappaceum) fruit endocarp extracts against human hepatocellular carcinoma (HepG-2) cells. Saudi Journal of Biological Sciences. 2021 Mar 1;28(3):1816-25. Available from: https://www.sciencedirect.com/science/article/pii/S1319562X2030680X 
  5. Muhtadi M, Haryoto H, Sujono TA, Suhendi A. Antidiabetic and antihypercholesterolemia activities of rambutan (Nephelium lappaceum L.) and durian (Durio zibethinus Murr.) fruit peel extracts. Journal of Applied Pharmaceutical Science. 2016 Apr 30;6(4):190-4. Available from: https://japsonline.com/admin/php/uploads/1848_pdf.pdf 
  6. Ahmad SA, Palanisamy U, Tejo BA, Hassan SS. Geraniin extracted from the Nephelium lappaceum (rambutan) rind inhibits dengue virus type-2. International conference and expo on drug discovery and designing, Frankfurt 2015. Available from: https://www.longdom.org/conference-abstracts-files/2169-0138.S1.008-024.pdf 
  7. Chingsuwanrote P, Muangnoi C, Parengam K, Tuntipopipat S. Antioxidant and anti-inflammatory activities of durian and rambutan pulp extract. International Food Research Journal. 2016 Aug 1;23(3). Available from: http://www.ifrj.upm.edu.my/23%20(03)%202016/(5).pdf 
  8. Phuong NN, Le TT, Van Camp J, Raes K. Evaluation of antimicrobial activity of rambutan (Nephelium lappaceum L.) peel extracts. International journal of food microbiology. 2020 May 16;321:108539. Available from: https://www.sciencedirect.com/science/article/pii/S0168160520300337 
  9. Phang SC, Palanisamy UD, Kadir KA. Effects of geraniin (rambutan rind extract) on blood pressure and metabolic parameters in rats fed high-fat diet. Journal of integrative medicine. 2019 Mar 1;17(2):100-6. Available from: https://www.sciencedirect.com/science/article/pii/S2095496419300081 
  10. Thulaja NR. Rambutan [Internet]. Infopedia. [cited 2022Dec1]. Available from: https://www.nlb.gov.sg/main/article-detail?cmsuuid=f5af61c8-6be6-4ec3-bc4e-d6a4c08c55b8
  11. Jirapongsananuruk O, Jirarattanasopa N, Pongpruksa S, Vichyanond P, Piboonpocanun S. Glyceraldehyde-3-phosphate dehydrogenase as a major allergen in rambutan-induced anaphylaxis. Annals of Allergy, Asthma & Immunology. 2011 Jun 1;106(6):545-7. Available from: https://www.annallergy.org/article/S1081-1206(11)00188-8/abstract 
  12. Diana R, Rachmayanti RD, Anwar F, Khomsan A, Christianti DF, Kusuma R. Food taboos and suggestions among Madurese pregnant women: a qualitative study. Journal of Ethnic Foods. 2018 Dec 1;5(4):246-53. Available from: https://www.sciencedirect.com/science/article/pii/S2352618118301446 
  13. Rambutan Nephelium lappaceum L. Euphoria nephelium DC. Dimocarpus crinita Lour. [Internet]. Rambutan. [cited 2022Dec2]. Available from: https://www.hort.purdue.edu/newcrop/morton/rambutan.html
  14. Afzaal M, Saeed F, Bibi M, Ejaz A, Shah YA, Faisal Z, Ateeq H, Akram N, Asghar A, Shah MA. Nutritional, pharmaceutical, and functional aspects of rambutan in industrial perspective: An updated review. Food Sci Nutr. 2023 Apr 19;11(7):3675-3685. doi: 10.1002/fsn3.3379. PMID: 37457167; PMCID: PMC10345721. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10345721/

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