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Atibala: Benefits, Side Effects, Precautions & More

Introduction

Atibala, scientifically called Abutilon Indicum (Linn.), belongs to the Malvaceae family. It is known as Country mallow in English, Kanghi in Hindi, and Atibala in Sanskrit. It’s a perennial shrub that grows up to 3 meters tall¹. 

The plant can be found in India, Sri Lanka, America’s tropical regions, and Malesia. It grows as a weed in sub-Himalayan areas, up to 1200 meters in elevation, and in hotter portions of India¹. 

Nutritional Benefits of Atibala

Abutilon Indicum (Linn) also known as atibala is a medicinal plant used in our Traditional System of Medicine to address various health problems¹.

Whole plant: Mucilaginous compounds, asparagines, saponins, flavonoids, and alkaloids are found throughout the plant. 

Atibala contains various essential oils like α-pinene, caryophyllene, caryophyllene oxide, endesmol, farnesol, borenol, geraniol, geranyl acetate, elemene, and α-cineole².  

Uses of Atibala

• Atibala acts as a demulcent, aphrodisiac, laxative, diuretic, and sedative.  
• It has been used to treat inflammation, piles, gonorrhoea, and boost immunity.  
• Aphrodisiac, anti-diabetic, antipyretic, anthelmintic, nerve tonic, and diuretic are properties of the root and bark. It may be useful in treating haematuria and leprosy. 
• Seeds: Urinary problems may be treated using seeds. The seeds are also used as a laxative in piles and as a remedy for cough. Puerperal sickness and chronic dysentery can also be treated with the seeds from this plant. 
• According to the Chinese in Hong Kong, the seeds are used as an emollient and demulcent.  
• The juice from its leaves has been used to make an ointment to help heal ulcers quickly.  
• Its extract is also used to treat bronchitis, diarrhoea, gonorrhoea, and bladder inflammation and reduce fever. 
• Atibala can also be used to clean wounds as well as to treat vaginal infections and as an enema³.

The Atibala plant has been used for its variety of medicinal properties since ancient times. It has shown positive effects on fever, allergy, bloody dysentery, etc. The Atibala tree’s bark is highly beneficial in tending to urinary complaints. Leaves of the Atibala tree work wonderfully on toothache, piles, and all kinds of inflammations.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Benefits of Atibala

1. Benefits of Atibala for Kidneys

• Atibala may aid in the prevention of diuresis.
• This is because it increases the amount of urine produced and excreted.
• This increases urine sodium loss while not affecting the intrinsic potassium-sparing action⁴.

2. Benefits of Atibala for Arthritis

• Atibala may help manage the symptoms of Rheumatoid Arthritis.
• It has analgesic and anti-inflammatory qualities.
• It also helps to minimize joint inflammation.
• Abutilon Indicum offers considerable protection against protein denaturation and RBC membrane damage caused by hypotonic saline⁴.

3. Benefits of Atibala for Diarrhoea

• Atibala may be beneficial for diarrhoea as it possesses anti-diarrheal properties.
• In addition, it reduces gastrointestinal motility and slows the contraction of intestinal muscles.
• This helps prevent stomach aches, pain, and loose or watery stools⁴.

4. Benefits of Atibala for Epilepsy and Seizures

• Atibala may be useful in the treatment of seizures.
• It contains linoleic acid and/or flavonoid components, which have anticonvulsant properties and prevent muscles from contracting involuntarily⁴.

5. Benefits of Atibala for Skin

• Atibala has antioxidant, anti-inflammatory, and antibacterial qualities that may aid wound healing.
• Atibala has ingredients that aid in wound contraction and closure, as well as skin cell regeneration.
• It also helps to promote wound healing by lowering the risk of infection at the wound site⁴. 

6. Benefits of Atibala for Diabetes

• Insulin sensitivity is improved by using Atibala.
• In addition, Atibala’s ability to regulate adipocyte development and increase glucose utilization may make it useful for lowering insulin resistance⁴.

7. Benefits of Atibala for Female Reproductive System

• The herb Abutilon Indicum has anti-oestrogenic properties.
• It was discovered that it suppressed enzyme activity and the uterotropic response induced by oestrogen⁴.

8. Benefits of Atibala for Immunity

• Atibala leaves may have immunomodulatory properties.
• It boosts antibody production in the blood and neutralizes infections.
• This aids in the improvement of the immune system⁴.

9. Benefits of Atibala for Infections

• In the case of Gram-positive bacteria, the extract of Abutilon Indicum was found to be most effective against Staphylococcus aureus, followed by Bacillus sublitis.
• In the case of Gram-negative bacteria, the extract was most effective against Escherichia coli, which showed the largest zone of inhibition, followed by Pseudomonas aeruginosa. In addition, the ethanolic extract had a lot of antifungal activity against Candida albicans⁴.

10. Benefits of Atibala for Respiratory System

• Dried aerial parts of Abutilon Indicum help alleviate the frequent bronchial asthma-like symptoms: dyspnea, cough, chest tightness and wheezing.
• It was also found to improve pulmonary function in patients with mild to severe bronchial asthma, as evaluated by forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and peak expiratory flow rate (PEFR)⁴.

In Unani medicine, the seeds of Atibala trees are used as a tonic and used for the management of bronchitis, chest troubles, piles, and gonorrhoea. The smoke of its seeds on charcoal is used to treat threadworms in children’s rectum. Similarly, its root has many health benefits and is used as a cooling medicine, laxative, pulmonary sedative, demulcent and diuretic.

Dr. Rajeev Singh, BAMS

How to Use Atibala?

• The leaves and seeds can be crushed with water to make a paste . 
• The leaves can be used as a paste, juice or as a whole as well. 
• A blend of leaf powder and wheat flour can also be used.  
• A fruit decoction combined with ammonium chloride can be taken orally with water. 
• Seed powder is taken orally with water. 
• The plant’s roots can be used in the form of powder.  
• Root infusion can also be used⁵.

Your doctor will prescribe you the appropriate form based on your individual needs.

Side Effects of Atibala

Atibala is safe to use and shows no side effects or toxicity in humans⁶.

Precautions to Take with Atibala

• Avoid using concomitantly with antidiabetic drugs as it may cause hypoglycemia. 
• Use with caution along with diuretic medicines⁴.
• No studies are available on usage of atibala in pregnant, or lactating mothers. 
• There is no study available on safety of atibala in use for children. 

Also Read: 6 Ayurvedic Science-Backed Benefits Of Moringa!

Frequently Asked Questions (FAQs)

Reference

1. Gautam V, Aslam P, Bharti K, Singhai AK. IJRPC 2013, 3(1) Vadnere Gautam et al ABUTILONS INDICUM LINN: A PHYTOPHARMACOLOGICAL REVIEW. Available from: https://ijrpc.com/files/24-331.pdf

2. Sharma, A. & Sharma, R.A. & Singh, H.. (2013). Phytochemical and pharmacological profile of Abutilon Indicum L. sweet: A review. International Journal of Pharmaceutical Sciences Review and Research. 20. 120-127. Available from: https://globalresearchonline.net/journalcontents/v20-1/20.pdf

3. Khadabadi, Somashekhar & Bhajipale, N.S.. (2010). A review on some important medicinal plants of Abutilon spp. Research Journal of Pharmaceutical, Biological, and Chemical Sciences. 1. 718-729. Available from: https://www.researchgate.net/publication/286712315_A_review_on_some_important_medicinal_plants_of_Abutilon_spp

4. Raja, Ramasubramania & Kailasam, Koumara. (2015). Abutilon indicum L (Malvaceae)-Medicinal Potential Review. Pharmacognosy Journal. 7. 330-332. 10.5530/pj.2015.6.2. Available from: https://www.researchgate.net/publication/281563912_Abutilon_indicum_L_Malvaceae-Medicinal_Potential_Review

5.  Mohite M S, Shelar P A, Raje V N., Babar S. J., Sapkal R. K.. Review on Pharmacological Properties of Abutilon indicum. Asian J. Pharm. Res. 2(4): Oct. – Dec. 2012; Page 156-160.  Available from: https://asianjpr.com/ShowPDF_Paper.aspx

6. Pingale, S.S. & Virkar, P.S.. (2011). Evaluation of acute toxicity for Abutilon indicum. 3. 37-42. Available from: https://www.scholarsresearchlibrary.com/articles/evaluation-of-acute-toxicity-for-abutilon-indicum.pdf

Disclaimer:The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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2

Ashwagandharishta: Uses, Benefits, Side Effects & More!

Introduction

Ashwagandharishta is an Ayurvedic polyherbal preparation known for its varied potential uses. Ashwagandharishta is widely used in the branch of Rasayana, which lengthens lifespan and rejuvenates the body. The name Ashwagandharishta comes from its chief ingredient Ashwagandha, a herb¹.

Ingredients of Ashwagandharishta

The list of ingredients of Ashwagandharishta are: 

• The roots of Ashwagandha (Withania somnifera)  
• Kali musali (Curculigo orchioides)  
• The roots of Manjistha (Rubia cordifolia) 
• Haritaki (Terminalia chebula)  
• Haridra (Curcuma longa)  
• Daruharidra (Berberis aristata)  
• The roots of Yasti (Glycyrrhiza glabra)  
• The roots of Rasna (Alpinia chinensis)  
• Vidari (Pueraria tuberosa)  
• The bark of Arjuna (Terminalia arjuna)  
• The rhizomes of Mustaka (Cyperus rotundus)  
• Trivrt (Ipomoea turpethum)  
• Svet Sariva (Hemidesmus indicus)  
• Krisna sariva (Ichnocarpus frutescens) 
• Svet Chandan (Santalum album)  
• Rakta Chandan (Pterocarpus santalinus)  
• Vacha (Acorus calamus)  
• Chitraka (Plumbago zeyleynica)  
• Dhataki (Woodfordia floribunda)  
• Sonth (Zingiber officinalis)  
• Marica (Piper nigrum) 
• Pippali (Piper longum)  
• The inner bark of Tvak (Cinnamomum zeyleynicum)  
• Tejpatra (Cinnamomum tamala)  
• Priyangu (Callicarpa microphylla) 
• Elaichi (Eletteria cardamomum)  
• stamens of Nagakesara (Mesua ferrea)  
• Madhu (Honey)  
• Water for decoction¹. 

Potential Uses of Ashwagandharishta

Ashwagandharishta is a well-known Ayurvedic remedy with immense potential uses. The roots of Ashwagandha are used as an adaptogen in both Ayurveda and Unani medicine². Some of the key medicinal qualities of Ashwagandharishta are: 

• Neuroprotective² 
• Memory-boosting² 
• Hematopoietic² 
• Sleep-stimulating² 
• Anxiolytic² 
• Antioxidant² 
• Cardioprotective³ 
• Anti-Hyperlipidaemic⁴ 
• Anti-inflammatory
• Collagenase inhibitor
• Antimicrobial
• Anticonvulsant
• Antidepressant
• Anti-epileptic 
• Removal of sodium and potassium in urine¹ 

Did you know that the fermentation process known as “Asava-Arishta” is used to make Ashwagandharishta. In this method, the herbs are soaked in water or a decoction with honey or jaggery, and then they are fermented for a predetermined amount of time. The medicinal qualities of the herbs are enhanced by this fermentation¹⁰.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Benefits of Ashwagandharishta

1. Benefits of Ashwagandharishta for Diuresis

• High Blood pressure (hypertension) and oedema associated with congestive heart failure, nephrotic syndrome (kidney disorder) and liver cirrhosis are generally handled by diuresis therapy⁸. 
• Ashwagandharishta is one of the excellent Ayurvedic remedies proven to help manage this disorder in laboratory settings.
• It is proven to be equivalent to the allopathic drug furosemide, a diuretic medication available in the market.
• Ashwagandharishta may be able to remove excess fluids by increasing the excretion of urine and removal of excess sodium, potassium, or chloride in such patients.
• Further studies are required to prove the efficacy in humans, but the studies so far have been promising¹.

2. Benefits of Ashwagandharishta for Heart

• Heart attack is a fatal outcome of an imbalance between the coronary blood supply and demand.
• Ashwagandharishta can protect the heart muscles owing to its antioxidant properties.
• Ashwagandharishta can reduce serum cholesterol, LDL, and triglycerides, subsequently increasing the HDL.
• The accumulation of LDL and triglycerides on the arteries and aorta is the primary cause of heart attack, which may be prevented by using Ashwagandharishta³.                                                 

3. Benefits of Ashwagandharishta for Gastric Ulcer

• Ashwagandharishta may be effective in relieving the symptoms of gastric ulcers.
• It can significantly reduce the total secretion of acid and protect the gastric mucosa lining⁷.
• Ashwagandharishta is also used for enhancing the power of digestion and preventing fainting due to weakness⁶

4. Benefits of Ashwagandharishta for Cholesterol

• Ashwagandharishta consists of the roots of ashwagandha that are very efficient in reducing low-density lipoprotein (bad cholesterol), triglycerides and total cholesterol.
• In addition, it can also increase the levels of high-density lipoprotein (good cholesterol).
• Further investigations are necessary to prove the efficacy in humans⁵.

5. Benefits of Ashwagandharishta for Memory disorders

• Ashwagandharishta can be helpful in memory disorder therapies due to its use as an anti-depressant.
• In Ayurvedic therapy, Ashwagandharishta is used in psychiatric disorders like epilepsy, depression, anxiety, schizophrenia, sluggishness, dullness, and other memory-related disorders⁴.
• The roots of ashwagandha are very efficient in promoting memory, attention and concentration.
• Therefore, Ashwagandharishta may be used to manage the symptoms of neurodegenerative diseases like Parkinson’s disease and Alzheimer’s⁹.
• Ashwagandharishta works by boosting neurotransmission, synaptic flexibility, and acts as an anti-depressant.
• It may be used to prevent stress and anxiety⁶. 

6. Benefits of Ashwagandharishta for Longevity

• Ashwagandharishta is an Ayurvedic tonic known to stimulate health and long life.
• It can prevent the ageing process and rejuvenate the body.
• It helps the body preserve and maintain energy throughout the day and enables good sleep which helps one feel re-energized the next day.
• It can also improve the haemoglobin levels by increasing the red blood count in adults.
• In children, it is used to promote growth^6,9. 

7. Benefits of Ashwagandharishta for Stress and Anxiety

• The anti-stress property of the Ashwagandharishta makes it an excellent remedy to improve mental well-being in obese and overweight adults.
• It can reduce stress and improve eating behaviours while sustaining the endocrinological balance. 
• It is also found that the roots of Ashwagandha can significantly reduce the levels of stress hormone and improve the quality of sleep².

According to Ayurveda, Ashwagandharishta might help in reducing stress and anxiety by balancing the Vata and Pitta doshas. The Vata and Pitta are said to be involved in maintaining the energy flow and various bodily functions. Additionally, Ashwagandha, one of the major ingredients of Ashwagandharishta is said to have adaptogenic properties that can help in reducing stress and anxiety^11,12.

Dr. Rajeev Singh, BAMS

Also Read: Lavender – Uses, Benefits & Side Effects

How to Use Ashwagandharishta?

Ashwagandharishta is an ayurvedic tonic that is prescribed by the physician to be taken as directed⁶.

Your Ayurvedic physician will prescribe you the form and dosage as per your health condition. 

Also Read: Gokshura – Uses, Benefits, Side Effects & Precautions

Side Effects of Ashwagandharishta

 The most common side effects of Ashwagandha, which is the chief ingredient of Ashwagandharishta are: 

• Intestinal disorders in hyperthyroid patients and pregnant women⁹
• Hypnotic effect in high doses⁹
• Drowsiness or sleepiness⁹

Ashwagandharishta might help in increasing sperm count. According to a small-scale study, root extracts of ashwagandha, which is the main ingredient of Ashwagandharishta powder are believed to have spermatogenic activities which can stimulate sperm count^13,14.

Dr. Smita Barode, B.A.M.S, M.S.

Precautions to Take with Ashwagandharishta

Ashwagandha, which is one of the significant ingredients of Ashwagandharishta, must be used with caution in certain health conditions like 

• Pregnancy⁹ 
• Hyperthyroidism⁹
• Due to the risk of causing hypnotic effect, the dosage of Ashwagandha must be charted out thoughtfully⁹.
• Kidney patients should undergo a kidney function test before starting Ashwagandharishta and must be followed up regularly to keep a close watch on any complications⁶.

Also Read: Triphala – Uses, Benefits & Side Effects

Frequently Asked Questions (FAQs)

References

1. Salve J, Pate S, Debnath K, Langade D. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus [Internet]. 2019 Dec 26 [cited 2022 Feb 28];11(12). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979308/ 

2. Ingale Dhanashri, Koppikar Soumya, Kulkarni Padmakumar, Harsulkar Abhay Madhukar. Benefits of Ashwagandharishta and Balarishta in Osteoarthritis are through Reduction of Inflammation and Inhibition of Collagenase | Request PDF. In: 2nd International Conference on Biotechnology and Bioinformatics [Internet]. 2015 [cited 2022 Feb 28]. Available from: https://www.researchgate.net/publication/280066103_Benefits_of_Ashwagandharishta_and_Balarishta_in_Osteoarthritis_are_through_Reduction_of_Inflammation_and_Inhibition_of_Collagenase 

3. Tanna IR, Aghera HB, K AB, Chandola HM, of Roga Nidana D, Vijnana V. Protective role of Ashwagandharishta and flax seed oil against maximal electroshock induced seizures in albino rats. Pharmacological Research [Internet]. 2012 [cited 2022 Feb 28];33(1). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3456848/pdf/Ayu-33-114.pdf 

4. Munaweera RRKW, Pandithavidana DR. Molecular Docking Analysis to Elucidate the Potential Drug Action of Phytochemicals Present in Ashwagandharishta towards Memory Related Disorders. In: International Postgraduate Research Conference 2018– University of Kelaniya [Internet]. 2018 [cited 2022 Feb 28]. Available from: https://www.researchgate.net/publication/329415276_Molecular_docking_analysis_to_elucidate_the_potential_drug_action_of_phytochemicals_present_in_Ashwagandharishta_towards_memory_related_disorders

5. Rahman T, Salahuddin Bhuiya M, Hasan R, Choudhuri MSK. Effect of Ashwagandharishta on the lipid profile of male and female rats. Jahangirnagar University Journal of Biological Sciences [Internet]. 2020 Jun 1 [cited 2022 Feb 28];9(1–2):59–68. Available from: https://www.banglajol.info/index.php/JUJBS/article/view/53707

6. Rahman T, Rakib Hasan M, K Choudhuri MS. Effect of Ashwagandharista (Withania somnifera) on the kidney functions of male and female rats. Jahangirnagar University Journal of Biological Sciences [Internet]. 2019 Aug 3 [cited 2022 Feb 28];8(1):1–7. Available from: https://www.banglajol.info/index.php/JUJBS/article/view/42462

7. Somuvel Uma, Venugopalan Rajesh, Jayakumar Vinothkumar, Kavitha K.N.V, Vijaykumar P.R.P, Perumal Perumal. Effect of a polyherbal liquid formulation on pylorus ligated gastric mucosal damage in albino wistar rats. Journal of Pharmacy Research [Internet]. 2011 [cited 2022 Feb 28];1115–7. Available from: https://www.researchgate.net/publication/283268849_Effect_of_a_polyherbal_liquid_formulation_on_pylorus_ligated_gastric_mucosal_damage_in_albino_wistar_rats

8. Furosemide | C12H11ClN2O5S – PubChem [Internet]. PubChem – National Library of Medicine. [cited 2022 Feb 28]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/furosemide 

9. Kumar Meher S, Das B, Panda P, Bhuyan G, Rao M. Uses of Withania somnifera (Linn) Dunal (Ashwagandha) in Ayurveda and its Pharmacological Evidences INTRODUCTION. Research Journal of Pharmacology and Pharmacodynamics [Internet]. [cited 2022 Feb 28];8(1). Available from: https://rjppd.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacology%20and%20Pharmacodynamics;PID=2016-8-1-6

10. Kushwaha R, Karanjekar S. Standardization of Ashwagandharishta formulation by TLC method. Int J ChemTech Res. 2011 Jul–Sep;3(3):1033-1036. Available from: https://sphinxsai.com/Vol.3No.3/Chem/pdf/CT=04(1033-1036)JS11.pdf

11. The Art of Living. Knowing vata imbalance: its symptoms, causes and remedies [Internet]. [cited 2025 Oct 08]. Available from: https://www.artofliving.org/in-en/ayurveda/remedies/vata-imbalance-manage

12. Salve J, Pate lwe Rahul, Kanchan A, Abbasi AR, Selvakumar S, Mohan A. Adaptogenic and anxiolytic effects of Withania somnifera (Ashwagandha) root extract in healthy adults: A double-blind, randomized, placebo-controlled clinical study. Indian J Psychol Med. 2019 Mar-Apr;41(3):242-51. PMCID: PMC6979308. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6979308/

13. Singh N, Bhalla M, de Jager P, Gilca M. An overview on Withania somnifera: a Rasayana (rejuvenator) of Ayurveda. Afr J Tradit Complement Altern Med. 2011;8(5 Suppl):208-213. PMCID: PMC3252722. doi:10.4314/ajtcam.v8i5S.9. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3252722/

14. Ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Withania somnifera in Oligospermic Males: A Pilot Study. Evid Based Complement Alternat Med. 2013;2013:571420. doi:10.1155/2013/571420. PMCID: PMC3863556. PMID: 24371462. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3863556/

Disclaimer:The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

25

2

Akarkara (Pellitory): Uses, Benefits, Side Effects & More!

Introduction

Anacyclus pyrethrum, commonly known as Akarkara in Hindi and Pellitory in English, is an important medicinal plant belonging to the Asteraceae family. It is also called Akkirakaram in Marathi. The roots of the plant have good therapeutic value as per the traditional systems of medicine¹. It is also known as the African pyrethrum. The species is Indigenous to Morocco, Spain, and Algeria and has two varieties: Anacyclus pyrethrum var. pyrethrum (L.) and Anacyclus pyrethrum var. depressus (Ball) Maire². Some varieties can be found in Jammu Kashmir, and Bengal. It is imported to India from Algeria¹.  

Chemical Constituents

Phytochemicals like alkaloids, coumarins, flavonoids, and tannins are present in the Anacyclus pyrethrum variety. The root extract contains free fatty acids, sterols, and unsaturated amides. Pellitorin, anacyclin, phenylethylamine, inulin, polyacetylenic amides, and sesamin¹. 

Nutritional Benefits

Phytochemical screening of Akarkara shows the presence of carbohydrates, proteins, and amino acids³. 

Akarkara Uses

The therapeutic uses of Akarkara are due to the presence of phytochemicals like Flavonoids and terpenoids. The roots and leaves of the Akarkara have a therapeutic role in the traditional Unani and Ayurvedic systems of medicine as well as the herbal medicine of the East¹.    

The plant is used as an  

• anti-inflammatory  
• antibacterial  
• aphrodisiac  
• antiviral  
• carminative  
• diuretic  
• emmenagogue (stimulate menstrual flow)  
• vermifuge (anthelmintic)  
• febrifuge (reducing fever)  
• sialagogue (stimulate saliva)  
• analgesic (pain reliever)  
• antiarthritic  
• nerve tonic¹ 

Maintain your oral health by using a herbal formulation (dantkanti) containing Akarkara (Anacyclus pyrethrum). Akarkara might help in strengthening teeth and gums and relieves toothache as they possess antibacterial, analgesic, and anti-inflammatory properties⁶.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Benefits Of Akarkara

1. Benefits of Akarkara in Diabetes

• Oral administration of the root extract of Akarkara was beneficial in bringing down spiked blood glucose levels in diabetic animal models.
• Akarkara could show antidiabetic benefits in animal studies.
• Further trials on humans are awaited to make it available as mainstream anti-diabetes medication¹.  

2. Benefits of Akarkara on the Central Nervous System (CNS)

• Akarkara root extract produced significant antidepressant effects in animal studies.
• Akarkara also showed muscle relaxant benefits in animal models¹.
• Extract of Akarkara enhanced memory and showed improvement in cognitive processes by increasing the brain levels of the enzyme cholinesterase⁴. 
• Extract of Akarkara also showed anticonvulsant activity.
• The extract reduced seizures associated with cognitive impairment and reduced oxidative stress in an experimental model of seizures⁵. Animal studies have confirmed the CNS activities of Akarkara.
• However, the same activities are yet to be established in humans through trials.  

3. Benefits of Akarkara for Immunity

• Akarkara extract showed immunostimulatory activity in rat models.
• There was a huge improvement in the humoral as well as the cellular component of immunity.
• The results suggest the potential use of Akarkara as an immunomodulator in the Ayurvedic system of medicine¹.  

4. Benefits of Akarkara in Wound Healing

• Akarkara plant extract showed wound healing benefits in rats which were evident by the improvement in the wound diameter.
• The wound-healing activity of Akarkara could be attributed to its antibacterial properties.
• The wound healing benefit could also be attributed to the anti-inflammatory activity of Akarkara².  

Polysaccharides extracted from the root of Anacyclus pyrethrum may possess anti-inflammatory and antioxidant properties. These properties can help in reducing various allergy-causing respiratory ailments⁷.

Dr. Rajeev Singh, BAMS

5. Benefits of Akarkara as a Fertility Enhancer

• The root extract of the Anacyclus pyrethrum improved the sexual potential of rats in an animal trial.
• Extract of Anacyclus pyrethrum also showed a potent libido-enhancing ability, along with its fertility-enhancing effects in several animal trials.
• Akarkara extract has shown promising results as a fertility enhancer in animal trials, but these activities are yet to be confirmed in humans¹.  

Improve your digestive health with Akarkara. Akarkara roots might aid in increasing and stimulating the secretion of saliva and other digestive juices which help in improving digestive health. Additionally, they might facilitate gas flatulence due to their carminative property⁸.

Dr. Smita Barode, B.A.M.S, M.S.

How To Use Akarkara?

Akarkara can be used in powdered form. The powder can be taken with honey.

An Ayurvedic physician will better guide you on the dose and frequency of taking the powder.  

Also Read: Ashokarishta – Uses, Benefits, Side Effects & Precautions

Precautions To Take with Akarkara

• There are no safety studies about its usage in pregnant and breastfeeding women. Therefore, it should be used with the doctor’s advice and supervision.   
• There are no safety studies about its usage in children.  

Also Read: Triphala: Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

There is a lack of data regarding the interaction of Akarkara with other drugs. Therefore, patients are advised to talk to a doctor about its usage if using any other medication or supplement.  

Also Read: Kumaryasava – Uses, Benefits & Side Effects

Frequently Asked Questions (FAQs)

References

1. Estimation Of Total Phenolic, Total Flavonoids And Total Protein Content Of Hydroalcoholic Extract Of Anacyclus Pyrethrum | Request PDF [Internet]. [cited 2022 Feb 24]. Available from: https://www.researchgate.net/publication/333746572_ESTIMATION_OF_TOTAL_PHENOLIC_TOTAL_FLAVONOIDS_AND_TOTAL_PROTEIN_CONTENT_OF_HYDROALCOHOLIC_EXTRACT_OF_ANACYCLUS_PYRETHRUM  

2. Pandey S, Rani Kushwaha G, Singh A, Singh A. Chemical Composition And Medicinal Uses Of Anacyclus Pyrethrum. 2018; Available from: https://www.researchgate.net/publication/324042819  

3. Elazzouzi H, Fadili K, Cherrat A, Amalich S, Zekri N, Zerkani H, Tagnaout I, Hano C, Lorenzo JM, Zair T. Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review. Plants (Basel). 2022 Sep 30;11(19):2578. doi: 10.3390/plants11192578. PMID: 36235444; PMCID: PMC9573456. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9573456/

4. Ibrahim RM, Abdel-Baki PM, Elmasry GF, El-Rashedy AA, Mahdy NE. Combinative effects of akarkara root-derived metabolites on anti-inflammatory and anti-alzheimer key enzymes: integrating bioassay-guided fractionation, GC-MS analysis, and in silico studies. BMC Complement Med Ther. 2023 Nov 17;23(1):413. doi: 10.1186/s12906-023-04210-6. PMID: 37978514; PMCID: PMC10655324. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10655324/

5. Pahuja M, Mehla J, Reeta KH, Joshi S, Gupta YK. Root extract of Anacyclus pyrethrum ameliorates seizures, seizure-induced oxidative stress and cognitive impairment in experimental animals. Epilepsy Res. 2012 Feb;98(2-3):157-65. doi: 10.1016/j.eplepsyres.2011.09.006. Epub 2011 Oct 12. PMID: 21993359. Available from: https://pubmed.ncbi.nlm.nih.gov/21993359/

6. Singh K, Singh P, Oberoi G. Comparative studies between herbal toothpaste (Dantkanti) and non‑herbal toothpaste. Int J Dent Res. 2016;4(2):53‑56. DOI:10.14419/ijdr.v4i2.6633. Available from: https://www.researchgate.net/publication/328600529_Comparative_studies_between_herbal_toothpaste_dantkanti_and_non-herbal_tooth_paste

7. Alliouche K, Benosmane L, Namoune S, Ouled‑Diaf K, Ghaliaoui N, Bendjeddou D. Anti‑inflammatory and antioxidant activity of the hot water‑soluble polysaccharides from Anacyclus pyrethrum (L.) Lag. roots. J Ethnopharmacol. 2021 Dec 5;281:114491. DOI:10.1016/j.jep.2021.114491. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0378874121007200

8. Usmani A, Khushtar M, Arif M, Siddiqui MA, Sing SP, Mujahid M. Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight. J Appl Pharm Sci. 2016 Mar;6(3):144‑50. Available from: https://japsonline.com/admin/php/uploads/1818_pdf.pdf

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

9

2

Arjunarishta: Uses, Benefits, Side Effects & More!

Introduction

Arjunarishta, also known as Parthadyarishta, is a hydroalcoholic formulation of the herb Terminalia arjuna belonging to the Combretaceae family¹. It is consumed as a herbal decoction. Arjunarishta is made up of fresh stem bark of Arjuna (Terminalia arjuna), Madhuka (Madhuka indica), Draksha (Vitis vinifera), Dhataki (Woodfordia fruticosa), and Jaggery (Saccharum officinarum). Among these, Arjuna constitutes the highest proportion. It is formulated via a fermentation process that generates alcohol. This alcohol acts as a preservative as well as a solvent².  

Chemical Constituents of Arjunarishta

Arjuna bark contains many phytochemicals, triterpenoids, glycosides, flavonoids, tannins, beta-sitosterol, minerals, and trace elements⁶.  

• Triterpenoids: Arjunin, arjunic acid, arjunolic acid, arjungenin, terminic acid, ajunglucosides IV and V, arjunasides A–E, 2″α,3″β-dihydroxyurs-12,18-dien-28-oic acid 28-O-β-D-glucopyranosyl ester   
• Flavonoids: Arjunolone, arjunone, baicalein, luteolin, gallic acid, ethyl gallate, quercetin, kempferol, pelargonidin, oligomeric proanthocyanidins 
• Glycosides: Arjunetin, arjunoside I, arjunoside II, arjunaphthanoloside, terminoside A 
• Tannins: Pyrocatechols, punicallin, punicalagin, terchebulin, terflavin C, castalagin, casuariin, casuarinin 
• Minerals and trace elements: Calcium, aluminium, magnesium, silica, zinc, copper

Uses of Arjunarishta

• Arjunarishta may help regulate blood pressure⁵. 
• Arjunarishta contains many phytochemicals that may function as antioxidants. Phytochemicals like flavonoids, glycosides, phenolic acids, and triterpenoids show antioxidant effects and free radical scavenging ability⁶. This free radical scavenging activity may effectively prevent liver and kidney damage. 
• Arjunarishta is also traditionally used in:
  • Lung disorders
  • Heart diseases⁶
  • absence of motile sperm
  • Loss of strength and immunity

Also Read: Dashmularishta: Uses, Benefits, Side Effects & More!

Benefits of Arjunarishta

Various phytochemicals present in Arjunarishta may provide many health benefits. Phytochemicals like flavonoids, glycosides, phenolic acids, and triterpenoids possess antioxidant effects and free radical scavenging ability that can reduce inflammation. 

1. For Diabetes

• Arjunarishta may support blood sugar control and improve insulin sensitivity⁵.
• Arjunarishta may be helpful in managing hyperglycemia, potentially benefiting individuals with diabetes.

2. For Heart Diseases

• Arujunarishta nourishes and strengthens the muscles of the heart¹.
• It helps regulate blood cholesterol and blood pressure¹.
• The chief constituent of Arjunarishta, Arjuna may reduce angina pain and be beneficial in managing coronary artery disease and heart failure¹.

3. For Cancer

• The major ingredient of Arjunarishta, arjuna bark, was found to be effective in controlling tumour formation in animal studies³.
• Vitis vinifera has shown anticancer abilities too and was efficacious in killing cancer cells in in vitro studies⁴.

However, more research is needed to understand their efficacy in treating cancer in humans.  

Traditional uses of Arjunarishta are obtained mainly from its bark. The renowned ancient physician Chakradatta advised administering it as a bark decoction with milk or as a ghrita. It has been observed that consuming a decoction of bark might help in reducing headaches, earache and heart ailments. Dried bark powder mixed with rice water might help in reducing blood in the urine¹.

Dr. Rajeev Singh, BAMS

How to Use

 As per the Ayurvedic Pharmacopoeia of India, Arjunarishta is to be taken after meals with water¹.  Dosage should be prescribed by an Ayurvedic physician based on individual health needs.

Side Effects

• Consumption of arjuna is associated with mild side effects like body aches, headaches, gastritis, and nausea¹. 
• Consuming excess amounts of arjuna plant extract, which is the critical component of Arjunarishta, can lead to hepatotoxicity and hypothyroidism¹.

Also Read: Drumstick (Sahjan): Uses, Benefits, Side Effects and More!

Precautions to Take

• There are no safety studies about its usage in pregnant and breastfeeding women. Therefore, it should be used only with the doctor’s advice and supervision in pregnant and nursing women.   
• There are no safety studies about its usage in children.  
• Arjunarishta is known to contain alcohol, which is self-generated during the fermentation process.

Mentioned in ancient Indian medicinal texts like Charaka Samhita, Sushruta Samhita and Ashtanga Hridayam, Arjunarishta might hold ultimate medical value in managing cardiovascular diseases. Vagabhatta was the one who originally suggested using stem bark powder for heart conditions¹. 

Dr. Siddharth Gupta, B.A.M.S M.D (Ayu)

Also Read: Atibala: Benefits, Side Effects, Precautions & More

Interaction with Other Drugs

There is a lack of data regarding the interaction of Arjunarishta with other drugs. Therefore, patients are advised to talk to a doctor about its usage if they are already using any other medication or supplement. 

Frequently Asked Questions (FAQs)

References

1. Dwivedi S, Chopra D. Revisiting Terminalia arjuna – An Ancient Cardiovascular Drug. Journal of traditional and complementary medicine [Internet]. 2014 Oct 1 [cited 2022 Feb 17];4(4):224–31. Available from: https://pubmed.ncbi.nlm.nih.gov/25379463/ 

2. Effect of Terminalia arjuna stem bark on antioxidant status in liver and kidney of alloxan diabetic rats – PubMed [Internet]. [cited 2022 Feb 17]. Available from: https://pubmed.ncbi.nlm.nih.gov/17051732/  

3. Sivalokanathan S, Vijayababu MR, Balasubramanian MP. Effects of Terminalia arjuna bark extract on apoptosis of human hepatoma cell line HepG2. World J Gastroenterol. 2006 Feb 21;12(7):1018-24. doi:10.3748/wjg.v12.i7.1018. PMID: 16534840; PMCID: PMC4087891. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087891/

4. Grace Nirmala J, Evangeline Celsia S, Swaminathan A, Narendhirakannan RT, Chatterjee S. Cytotoxicity and apoptotic cell death induced by Vitis vinifera peel and seed extracts in A431 skin cancer cells. Cytotechnology [Internet]. 2018 Apr 1 [cited 2022 Feb 22];70(2):537–54. Available from: https://pubmed.ncbi.nlm.nih.gov/28983752/ 

5. Shengule SA, Mishra S, Joshi K, Apte K, Patil D, Kale P, et al. Anti-hyperglycemic and anti-hyperlipidaemic effect of Arjunarishta in high-fat fed animals. J Ayurveda Integr Med. 2018 Jan-Mar;9(1):45-52. doi:10.1016/j.jaim.2017.07.004. PMID: 29249636; PMCID: PMC5884182. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884182/

6. Amalraj A, Gopi S. Medicinal properties of Terminalia arjuna (Roxb.) Wight & Arn.: A review. J Tradit Complement Med. 2016 Mar 20;7(1):65-78. doi:10.1016/j.jtcme.2016.02.003. PMID: 28053890; PMCID: PMC5198828. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198828/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

33

1

Kumaryasava: Uses, Benefits, Side Effects & More!

Introduction

Kumaryasava is an Ayurvedic formulation, which has aloe vera as the main ingredient. Asavas are medicinal preparations prepared by soaking the drugs (decoction or powder) in a solution of jaggery or sugar for a definite period. It undergoes the fermentation process by producing alcohol, which facilitates the extraction of active constituents of drugs. Kumaryasava is composed of Aloe barbadensis, Terminalia chebula, Ricinus communis, Myristica fragrans, Syzygium aromaticum, Woodfordia fruticosa, Piper cubeba, Nardostachys jatamansi, jaggery and water². As per the Ayurvedic Pharmacopoeia of India, Kumaryasava should comprise not less than 5% v/v and not more than 10% v/v of self-generated alcohol³. Phytochemical analysis of Kumaryasava showed the presence of saponins, phenolic compounds, tannins, and anthraquinone glycosides¹.  

Nutritional Value of Kumaryasava

The phytochemical screening of Kumaryasava showed the presence of carbohydrates in addition to phytochemicals¹.   

Uses of Kumaryasava

• The phytochemicals present in Kumaryasava, such as saponins, phenolic compounds, tannins, and anthraquinone glycosides, contribute to its various therapeutic uses¹.
• Kumaryasava is one of the most widely used over-the-counter products.
• It is used as a health tonic for adults and children to treat weak digestion, urinary disorders, liver impairment, and cough¹.  

In my clinical experience, Kumaryasava may help provide relief and support in managing discomfort associated with urinary tract stones. It’s sometimes considered as part of a natural approach to urinary tract health¹¹.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Benefits of Kumaryasava

As per Ayurvedic Pharmacopoeia of India, Kumaryasava is beneficial in managing various conditions like digestive impairment, duodenal ulcers, urinary disorders, bleeding disorders, epilepsy, worm infestation, loss of memory, weakness, diseases of the abdomen, and tastelessness⁴. 

1. Benefits of Kumaryasava as a Liver Protective Agent

• Kumaryasava has been widely used because of its various benefits in managing liver disorders.
• Kumaryasava provides protection against hepatotoxicity.
• Its hepatoprotective activity is attributed to the many antioxidant phytochemicals present in it.
• It is a useful hepatoprotective formulation⁵.  

2. Benefits of Kumaryasava in Treating Gastric Disorders

• Kumaryasava has many benefits in managing gastric conditions.
• Kumaryasava helps in relieving discomfort due to gas and acidity.
• It also relieves constipation.
• Additionally, it helps by stimulating digestive enzymes⁶. 

In clinical practice, Kumaryasava is sometimes considered helpful in managing issues like reduced appetite and supporting patients with diabetes. It is believed to stimulate digestive enzymes, which may aid in improving digestion¹³.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

3. Benefits of Kumaryasava in Managing Painful Periods

• According to a study, the administration of Kumaryasava was found to be safe and effective in relieving the signs and symptoms associated with dysmenorrhoea (medical term for painful periods).
• Kumaryasava could reduce the overall pain associated with dysmenorrhoea⁷.  

From a clinical point of view, Kumaryasava may help patients who experience painful or difficult urination (dysuria). Its main ingredient, Aloe vera, is known for its anti-inflammatory properties, which might help reduce discomfort¹¹.

Dr. Rajeev Singh, BAMS

How to Use Kumaryasava?

As per the Ayurvedic Formulary of India, Kumaryasava should be taken after meals and with water⁸. It can be taken with water for managing indigestion and constipation^9,10. The Ayurvedic Physician will prescribe you the form and dosage as per your health condition.

Did you know Kumaryasava is believed to aid in menopausal problems? This effect can be attributed to aloe vera as the major ingredient that helps to soothe the pain and difficulties associated with menopause¹².

Dr. Smita Barode, B.A.M.S, M.S.

Also Read: Amaltas (Golden Shower Tree): Uses, Benefits, Side Effects & More!

Precautions to Take with Kumaryasava

Patients with ongoing medication for chronic diseases should consult a doctor before using Kumaryasava. Keep the following points in mind: 

• During Pregnancy: There is a lack of data related to the safe use of Kumaryasava in pregnant women. Therefore use this medicine only after consulting the physician.  
• During Breastfeeding: There is not enough data to support its safe usage during breastfeeding. Therefore kindly follow the doctor’s advice before using it.  

Also Read: Pippali (Long Pepper): Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

As per the Essential drug list of Ayurveda, there are no specific contraindications associated with Kumarysava⁸. However, notify your doctor regarding all the medicines and health supplements that you take before taking Kumaryasava.  

Also Read: Babool (Acacia Nilotica): Uses, Benefits, Side Effects and More!

Frequently Asked Questions (FAQs)

References

1. Elamthuruthy AT, Shah CR, Khan TA, Tatke PA, Gabhe SY. Standardization of marketed Kumariasava – An Ayurvedic Aloe vera product. Journal of Pharmaceutical and Biomedical Analysis [Internet]. 2005 Apr 29 [cited 2022 Feb 11];37(5):937–41. Available from: https://www.researchgate.net/publication/7874865_Standardization_of_marketed_Kumariasava_-_An_Ayurvedic_Aloe_vera_product
2. Selvan PS, Sanmuga Priya E. Determination of ethanol content in ayurvedic formulations kumaryasava and mustakarista by gas chromatography. Indian Journal of Pharmaceutical Sciences [Internet]. 2015 Jan 1 [cited 2022 Feb 11];77(1):120. Available from: https://www.ijpsonline.com/articles/determination-of-ethanol-content-in-ayurvedic-formulations-kumaryasava-and-mustakarista-by-gas-chromatography.html
3. Jagdish Manwar RM, Satish Padgilwar MV. Effect of Preparation Method on Antioxidant Activity of Ayurvedic Formulation Kumaryasava. Journal of Homeopathy & Ayurvedic Medicine. 2012;01(04). Available from: https://www.semanticscholar.org/paper/Effect-of-Preparation-Method-on-Antioxidant-of-Manmode-Manwar/306c7e970a553ce38c2a7932b4cf8fedd6acb07a
4. The ayurvedic formulary of India | Part 1. Second Edition. Ayurvedic Pharmacopoeia Committee. Government of India. Available from: https://pcimh.gov.in/show_content.php?lang=1&level=1&ls_id=56&lid=54
5. Khan MA, Gupta A, Sastry JLN, Ahmad S. Hepatoprotective potential of kumaryasava and its concentrate against CCl4-induced hepatic toxicity in Wistar rats. Journal of Pharmacy & Bioallied Sciences [Internet]. 2015 Oct 1 [cited 2022 Feb 15];7(4):297. Available from: https://pubmed.ncbi.nlm.nih.gov/26681887/
6. Motghare KP, Yeokar V. A Review on Traditional Ayurveda Formulations and their Therapeutic Importance. Journal of Drug Delivery and Therapeutics [Internet]. 2019 May 15 [cited 2022 Feb 15];9(3):650–3. Available from: http://www.jddtonline.info/index.php/jddt/article/view/2663
7. Lal P, Lal SK, Garg S. A CLINICAL COMPARATIVE EVALUATION OF EFFICACY AND SAFETY OF KUMARYASAVA AND RAJAHPRAVARTANI VATI IN THE MANAGEMENT OF PRATHMIK KASTARTAVA W.S.R. TO (PRIMARY DYSMENORRHOEA): A PROSPECTIVE OPEN LABEL SINGLE CENTER STUDY. undefined. 2017. Available from: https://www.jahm.co.in/index.php/jahm/article/view/1688
8. Essential Drugs List (EDL)_Ayurveda | Department of Ayush Ministry of Health and Family Welfare, Government of India. Available from: https://nischennai.org/main/wp-content/uploads/2021/10/siddha-essential-drugs-list-2013.pdf
9. Ajirna (Indigestion) | National Health Portal of India [Internet]. [cited 2022 Feb 11]. Available from: https://www.researchgate.net/publication/366808191_Indigestion-induced_hyperacidity_Vidagdhajirna_treated_with_Ayurveda_therapy_a_single_case_study
10. Constipation (Vibandha) | National Health Portal of India [Internet]. [cited 2022 Feb 11]. Available from: https://www.researchgate.net/publication/360642968_Constipation-A_major_health_disorder_Role_of_herbal_medicine_treatment
11. Singhal R, Barla MA, Roushan R. Ayurvedic management of renal cyst – a case study. J Ayurveda. 2022;16:263-6. doi:10.4103/joa.joa_48_22. Available from: https://www.researchgate.net/profile/Rakesh-Roushan-3/publication/364292657_Ayurvedic_Management_of_Renal_Cyst/links/6343c294ff870c55ce14741a/Ayurvedic-Management-of-Renal-Cyst.pdf
12. Dey A, Dhadhal S, Maharjan R, Nagar PS, Nampoothiri L. Partially purified non-polar phytocomponents from Aloe barbadensis Mill. gel restores metabolic and reproductive comorbidities in letrozole-induced polycystic ovary syndrome rodent model—an “in-vivo” study. J Ethnopharmacol. 2022;291:115161. doi:10.1016/j.jep.2022.115161. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0378874122001994
13. Alexandar S, Joy JM. Pharmacognostical Evaluation and HPTLC profiling of the root of Triumfetta rhomboidea Jacq. Research Journal of Pharmacy and Technology. 2022;15(3):1245-0. doi:10.52711/0974-360X.2022.00208. Available from: https://rjptonline.org/AbstractView.aspx?PID=2022-15-3-51

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

11

Pashanbhed (Bergenia Ligulata): Uses, Benefits, Side Effects & More!

Introduction

Pashanbhed or stone breaker is a popular Indian drug. It is also called stonebreaker as it can dissolve kidney stones. Pashanbhed is derived from the plant Bergenia ligulata and is used in the indigenous system of medicine. Bergenia ligulata is a climbing plant that is distributed in moist areas of the Himalayas, Bhutan, Afghanistan, Meghalaya, Arunachal Pradesh, Sikkim, and south Tibet. The flowers of Bergenia ligulata are pink, purple, or white. According to the Ayurvedic system of medicine, Pashanbhed is used for various medicinal purposes. The rhizome, root, and leaves of Bergenia ligulata are used to treat a variety of ailments¹. 

Chemical Constituents of Pashanbhed

The rhizome of Pashanbhed contains many chemical constituents like arbutin, paashaanolactone, afzelechin, bergenin, norbergenin, catechin, minerals, glucose, albumin, vitamins, mucilage, ash, starch, and gallic acid. The constituents present in seeds of pashanbhed include tannic acid, coumarin, minerals, wax, coumarin, and gallic acid. The root of pashanbhed showed the presence of tannins, alkaloids, flavonoids, steroids, terpenoids, carbohydrates, saponins, and glycosides¹. 

Uses of Pashanbhed

Pashanbhed is used in the management of kidney and bladder stones, urinary problems, and other diseases due to its medicinal properties like: 

• Anti-inflammatory activity 
• Antilithic activity (preventing the formation of stones) 
• Antiviral activity 
• Anti-bradykinin activity 
• Antibacterial activity 
• Diuretic activity
• Liver protective activity 
• Antipyretic activity 
• Laxative  
• Analgesic 
• Aphrodisiac  
• Abortifacient^1,2  

Benefits of Pashanbhed

1. Benefits of Pashanbhed for Preventing Stone Formation

• Antiurolithic is the property of preventing or dissolving stones in the ureters, bladders, or kidneys.
• Pashanbhed inhibits the growth of calcium oxalate monohydrate crystals, which is responsible for the formation of kidney or urinary stones.
• Hot water extract of the Pashanbhed plant is taken orally for treating urinary or renal stones. Pashanbhed powder is also recommended to manage painful urination². 

2. Benefits of Pashanbhed as an Antidiabetic Medicine

• The alcoholic extract of roots of Pashanbhed contains hypoglycemic (blood sugar lowering) properties.
• It might reduce elevated blood sugar levels in diabetic patients.
• The antidiabetic effect might be due to the stimulation of insulin release or the stimulation of cells of pancreatic islets.
• Due to its anti-diabetic properties, Pashanbhed can be used as a component of medicines or nutraceutical foods for managing diabetes and associated symptoms². 

3. Benefits of Pashanbhed for the Liver

• The alcoholic extract of Pashanbhed showed a reduction in the levels of serum glutamic pyruvic transaminase (SGPT), serum glutamic oxaloacetic transaminase (SGOT), alkaline phosphatase (ALP), and total bilirubin.
• This confirmed the hepatoprotective (liver protecting) effect of Pashanbhed.
• Pashanbhed powder is also helpful for managing liver and spleen diseases, particularly enlarged spleen². 

4. Benefits of Pashanbhed as an Diuretic

• Diuresis refers to an increased passage of urine.
• Alcoholic extracts of roots of Bergenia ligulata proved to increase urinary electrolyte concentration of sodium, potassium, and chloride, which shows that it has diuretic properties.
• The diuretic property of the roots of Bergenia ligulata might be due to the presence of compounds like saponins and flavonoids². 

5. Benefits of Pashanbhed for the Reproductive System

• Pashanbhed powder helps nourish and correct the functioning of the reproductive system.
• Pashanbhed is also used for treating gynaecological problems³. 

6. Benefits of Pashanbhed for the Skin

• In India, dried roots of Pashanbhed have been used topically for treating boils, wounds, cuts, and burns.
• The hot water extract of Pashanbhed has been used externally for the treatment of boils². 

Did you know that Pashanbhed (Bergenia ligulata) contains a significant phenolic compound called ‘bergenin’ comprising approximately 0.9% of its composition? Along with bergenin, it also contains other phenolic compounds in smaller quantities. These compounds contribute to the potential health benefits and therapeutic properties associated with Pashanbhed⁶.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Pashanbhed?

Pashanbhed is available in two forms: 

• Powder 
• Decoction 

Some important formulations of Pashanbhed include Asmarihara kasaya churna, Mutravircaniya kasaya churna. The main preparations of Pashanbhed include Pashanbhed ghrit and Pashanbhed kwath^4,5.  

Your Ayurvedic physician will prescribe you the dose and form according to your medical condition. 

In my experience, I have observed that Pashanbhed (Bergenia ligulata) has a distinctive aromatic odour and astringent taste. These sensory properties can be attributed to its chemical constituents, which interact with our taste receptors and olfactory receptors⁶.

Dr. Rajeev Singh, BAMS

Side Effects of Pashanbhed

Pashanbhed is an important constituent of many formulations used for managing kidney diseases. However, the acetone extract of rhizomes of Pashanbhed is known to be cardiotoxic in large doses and produces a depressing effect on the central nervous system. A large dose of Pashanbhed is known to produce antidiuretic effects too. However, it is unlikely that these effects will be observed with doses in the normal range².

Also Read: Lohasava: Uses, Benefits, Side Effects and More!

Frequently Asked Questions (FAQs)

References

1. KM Ruby, Jaya Dwivedi, Rajani Chauhan; Pashanbheda A golden herb of Himalaya: A review. International journal of pharmacy review and research. 2012;2(2):97-105 Available from: https://www.semanticscholar.org/paper/PASHANBHEDA-A-GOLDEN-HERB-OF-HIMALAYA%3A-A-REVIEW-Ruby-Dwivedi/1c589e6f7fd1b2ba2ade0c752ec2135276d91784?p2df 

2. S.S Gurav and N.S Gurav; A comprehensive review: Bergenia ligulata wall- A controversial clinical candidate. International journal of pharmaceutical sciences and research. 2014;5(5): 630-1642 Available from: https://ijpsr.com/bft-article/a-comprehensive-review-bergenia-ligulata-wall-a-controversial-clinical-candidate/ 

3. Preeti choudhary, Parshant Bakshi and Rafiq Ahmad; Prospects of Bergenia: A medicinal herb (Pashanbhed). 2016. Available from: https://www.biotecharticles.com/Healthcare-Article/Prospects-of-Bergenia-A-medicinal-herb-Pashanbhed-3627.html 

4. The Ayurvedic pharmacopoeia of India. Part-1 Volume-1. Page no: 90. Available from: http://www.ayurveda.hu/api/API-Vol-1.pdf 

5. Vikaspedia. Bergenia Ciliata [Internet]. Available from: https://vikaspedia.in/agriculture/crop-production/package-of-practices/medicinal-and-aromatic-plants/bergenia-ciliata 
6. Das C, Kumari B, Singh MP, Singh S. A Literary Review and Therapeutic Action of Pashanbheda (Bergenia ligulata Wall) described by Shamhita in Ashmari Roga. J Ayurveda Integr Med Sci [Internet]. 2022 Aug 13 [cited 2025 Nov 18];7(6):105–114. Available from: https://jaims.in/jaims/article/view/1861/2238

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

8

Triphala Guggulu: Uses, Benefits, Side Effects & More!

Introduction

Triphala Guggulu is a traditional polyherbal formulation as per the Ayurvedic system of medicine. It is composed of resin of guggul (Commiphora wightii), long pepper (Piper longum), and Triphala (fruits of Phyllanthus emblica L., Terminalia chebula Retz, and Terminalia bellirica)¹. Triphala is a well-recognized polyherbal medicine classified as the tridoshic rasayan.  

The Triphala formulation contains the fruits Amalaki or the Indian Gooseberry, Bibhitaki, and Haritaki of the three plants². Triphala Guggulu is one of the most widely used among the other Guggulu formulations³. Phytochemical screening of Triphala Guggulu shows the presence of glycosides, alkaloids, saponins, flavonoids, tannins, and steroids⁴.   

Nutritional Value of Triphala Guggulu

Apart from various phytochemicals, phytochemical screening showed the presence of carbohydrates, proteins, and amino acids in Triphala Guggulu⁴. 

Uses of Triphala Guggulu

The uses of Triphala Guggulu are as follows: 

• Triphala Guggulu is used in managing inflammatory conditions, hyperglycemia, oxidative stress, and hypolipidemia⁵.  
• Triphala Guggulu is widely used in managing Vatarakta (gout), Bhagandar (fistula), Kushtha (leprosy), Vranaropana (wound healing), Pakvavidradhi (abscess), Gandamala (goitre), and Asthibhagna (fracture)⁴.  

Did you know Triphala Guggulu might aid in dental problems as well? Due to its anti-bacterial nature, Triphala Guggulu may be used for dental diseases such as swollen gums, cavities, and bleeding gums⁹.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Benefits of Triphala Guggulu

1. Benefits of Triphala Guggulu in Wound Healing

• Oral administration of Triphala Guggulu helps to heal wounds fast.
• It also leads to a reduction in pain associated with the wound.
• It can be a potential drug for wound healing due to its safety and cost-effectiveness⁶.  

2. Benefits of Triphala Guggulu in Piles

• Guggulu has anti-inflammatory benefits.
• It helps in healing the inflammation of the fistula.
• Triphala is beneficial in relieving constipation, a problem associated with hemorrhoids.
• In addition, Piper longum aids in the digestion and assimilation of food nutrients⁷.
• Though there are benefits associated with the use of Triphala Guggulu, it should not be used as an alternative to conventional therapy.  

3. Benefits of Triphala Guggulu in Managing Constipation

Triphala found in Triphala Guggulu helps in facilitating bowel movements and relieving constipation⁷. 

4. Benefits of Triphala Guggulu in Managing Diabetic Macular Oedema

• Diabetic macular edema is a common cause of visual impairment in diabetic patients.
• Oral administration of Triphala Guggulu could show improvement in the thickness of the retina and visual acuity⁵. 

5. Benefits of Triphala Guggulu in Managing Arthritis

• Triphala Guggulu is a Guggulu-based formulation beneficial in acute arthritis.
• The anti-arthritic activity of Triphala Guggulu is attributed to its anti-inflammatory activity.
• A study found that it also acts by inhibiting the enzymes that get activated in arthritis, namely hyaluronidase and collagenase⁸. 

Triphala Guggulu might be used as an useful remedy of choice for cancer! This herbal medicine might offer a natural solution for cancer with its antioxidant nature¹⁰.

Dr. Rajeev Singh, BAMS

How to Use Triphala Guggulu?

Triphala Guggulu can be taken with warm water. However, it should be used on the advice of an Ayurvedic doctor. The Ayurvedic doctor will prescribe you the dose and form based on the diagnosis.   

Also Read: Ashwagandha – Uses, Benefits, Side Effects & Precautions

Precautions to Take with Triphala Guggulu

You should keep the following points in mind: 

• Triphala Guggulu should not be used during pregnancy.  
• Triphala Guggulu is contraindicated in chronic and recurrent diarrhoea.
• Triphala Guggulu should be avoided during the breastfeeding period as there is a lack of data to support its safety . Use it only after consulting with an Ayurvedic doctor.  

Other than its anti-inflammatory nature, Triphala Guggulu has anti-oxidant characteristics as well. This makes Triphala Guggulu a potential medicine of choice for diseases like Atherosclerosis, Alzheimer’s disease, stroke and diabetes¹⁰.

Dr. Smita Barode, B.A.M.S, M.S.

Interaction with Other Drugs

There is a lack of sufficient data regarding the interaction of Triphala Guggulu with other drugs. Therefore, you must talk to a doctor about its usage if you are using any other medication or supplement.  

Exploring  the Potential of Triphala Guggulu in ear discharge treatment. It is believed that due to its anti-inflammatory properties, Triphala Guggulu may aid in the treatment of ear discharge (medically known as Chronic Suppurative Otitis Media)¹¹.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

Also Read: Chitrakadi Vati – Benefits, Precautions & Side Effects

Frequently Asked Questions (FAQs)

References

1. Babu Ks, Muguli G, Rao Vadaparthi P, Ramesh B, Gowda V, Paramesh R, et al. A novel high-performance liquid chromatography-electron spray ionization-mass spectrometry method for simultaneous determination of guggulsterones, piperine and gallic acid in Triphala guggulu. Pharmacognosy magazine [Internet]. 2015 [cited 2022 Feb 17];11(Suppl 1):66. Available from: https://pubmed.ncbi.nlm.nih.gov/26109777/ 

2. Peterson CT, Denniston K, Chopra D. Therapeutic Uses of Triphala in Ayurvedic Medicine. Journal of alternative and complementary medicine (New York, NY) [Internet]. 2017 [cited 2022 Feb 17];23(8):607–14. Available from: https://pubmed.ncbi.nlm.nih.gov/28696777/ 

3. CLINICAL EFFECTS OF TRIPHALA GUGGULU ON DIABETIC MACULAR EDEMA | Semantic Scholar [Internet]. [cited 2022 Feb 21]. Available from: https://www.semanticscholar.org/paper/CLINICAL-EFFECTS-OF-TRIPHALA-GUGGULU-ON-DIABETIC-Gautam-Chaurasiya/ac7e53abe58490244727071328d8490a4e13ae01 

4. Bhushan D Mhaiskar BPCB. Management of non-healing infected wound by external application of and Hinsradya Taila Triphala Guggulu Case Report [Internet]. 2017 [cited 2022 Feb 21]. p. 132–4. Available from: https://www.researchgate.net/publication/320111273_Management_of_non-healing_infected_wound_by_external_application_of_and_Hinsradya_Taila_Triphala_Guggulu_Case_Report 

5. Mehra R, Vyas N, Makhija R. A clinical study on the role of Ksara Vasti and Triphala Guggulu in Raktarsha (Bleeding piles). Ayu [Internet]. 2011 [cited 2022 Feb 21];32(2):192. Available from: https://pubmed.ncbi.nlm.nih.gov/22408301/ 

6. Sumantran VN, Kulkarni AA, Harsulkar A, Wele A, Koppikar SJ, Chandwaskar R, et al. Hyaluronidase and collagenase inhibitory activities of the herbal formulation Triphala guggulu. Journal of Biosciences 2007 32:4 [Internet]. 2007 Jul 9 [cited 2022 Feb 21];32(4):755–61. Available from: https://link.springer.com/article/10.1007/s12038-007-0075-3 

7. Essential Drugs List(EDL)_Ayurveda. Department of Ayush Ministry of Health and Family Welfare. Government of India. Available from: https://namayush.gov.in/sites/all/themes/webcms/images/essential_drugs/Ayurveda_EDL_list_final.pdf

8. Sumantran VN, Kulkarni AA, Harsulkar A, Wele A, Koppikar SJ, Chandwaskar R, Gaire V, Dalvi M, Wagh UV. Hyaluronidase and collagenase inhibitory activities of the herbal formulation Triphala guggulu. J Biosci. 2007 Jun;32(4):755-61. doi: 10.1007/s12038-007-0075-3. PMID: 17762148. Available from: https://pubmed.ncbi.nlm.nih.gov/17762148/

9. Prakash S, Shelke AU. Role of Triphala in dentistry. J Indian Soc Periodontol. 2014 Mar;18(2):132-5. doi: 10.4103/0972-124X.131299. PMID: 24872616; PMCID: PMC4033874. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4033874/

10. Verma P, Singh B, Kumar A, Sharma R, Kumar V. In-vitro anti-inflammatory and antioxidant potential of Triphala guggul tablets. J Med Herbs Ethnomedicine. 2020;6:45–47. doi:10.25081/jmhe.2020.v6.6238. Available from: https://pdfs.semanticscholar.org/180b/2dd40e458eac41ebaaa155ee02ab51e7583d.pdf

11. Nath S, Jadhav S, Mulik S, Nangare N, Mulik S, Lathwal N. A conceptual study of Triphala Guggul in Karnasrava (C.S.O.M). J Pharm Negative Results. 2023;14(Suppl 01):367–370. doi:10.47750/pnr.2023.14.S01.40. Available from: https://www.pnrjournal.com/index.php/home/article/view/6469

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

22

Chitrakadi Vati: Uses, Benefits, Side Effects & More!

Introduction

Chitrakadi vati is well recognised as an Ayurvedic preparation¹. It is a polyherbal formulation containing nine ingredients of herbal origin: Chitraka (Plumbago zeylanica), maricha (Piper nigrum), pippali (Piper longum fruit), pippalimoola (Piper longum root), Chavya (Piper chaba), ginger (Zingiber officinale), hing (Ferula foetida/Ferula asafoetida), ajmoda (Apium leptophyllum), yava ksara (Hordeum vulgare) and panchalavana (Samudra, Sauvarchala, Saindhava, Vida, Audbhida)².

Uses of Chitrakadi Vati

The uses of Chitrakadi Vati are as follows: 

• It is commonly used to manage irritable bowel syndrome, abdominal tumours, rheumatoid arthritis, and appetite loss.  
• It is also used as a digestive tonic and carminative. Chitrak stimulates digestion and appetite and aids in dealing with leprosy, fever, oedema, and scabies^1,2.  
• Long pepper is an anti-asthmatic, laxative, anti-infective agent in urinary tract infections, aphrodisiac, carminative, and analgesic¹. 
• Black pepper is used as a diuretic and analgesic and for managing constipation, piles, and colic¹.  
• Ginger is used to deal with heart problems and acts as a carminative¹. 

According to Ayurveda, Chitrakadi vati might be useful in decreasing mouth dryness caused due to increased levels of vatta and pitta levels and decreased kapha levels in the body. Chitrakadi vati might stimulate saliva secretion¹³.

Dr. Siddharth Gupta, MD, B.A.M.S, M.D (Ayu)

Benefits of Chitrakadi Vati

1. Benefits of Chitrakadi Vati Due to Laxative Activity

• The laxative efficacy of extract of Chitrakadi vati at various doses was studied¹ in rats.
• The extract of Chitrakadi vati showed significant laxative action by increasing the stool output weight.
• The presence of long pepper and black pepper in Chitrakadi vati contribute to the laxative properties. 

2. Benefits of Chitrakadi Vati for Ovulation

• According to a study³, Chitrakadi vati was one of the best medications for follicular rupturing tests.
• As a result, Chitrakadi vati was selected as a replacement for the human chorionic gonadotropin hormone for follicular rupture. 

3. Benefits of Chitrakadi Vati for Liver

• Consumption of Chitrakadi gutika formulation (tablet of various herbs) and buttermilk was found to be effective in dealing with non-alcoholic fatty liver disease by reversing the fatty infiltration of the liver⁴. 
• The liver-protective efficacy of extract of Chitraka roots was investigated in rats.
• The extract administration to rats dramatically reduced the serum marker levels, demonstrating that extract has a liver protective impact in restoring the hepatocytes’ normal function⁵. 

4. Benefits of Chitrakadi Vati for Managing Inflammation

• The anti-inflammatory activities of Chitraka leaf extract were studied⁵ in experimental animal models.
• The extract exhibits anti-inflammatory activity by reducing the prostaglandin synthesis and release. 

5. Benefits of Chitrakadi Vati for Managing Diabetes

• The antidiabetic effect of Chitraka roots extract was studied in rats.
• The root extract exhibited antidiabetic activity by increasing the hepatic hexokinase activity while decreasing serum acid phosphatase, hepatic glucose-6-phosphate, alkaline phosphatase and lactate dehydrogenase levels.
• The active constituent of the extract, plumbagin, significantly reduced the blood glucose levels in diabetic rats⁵. 

6. Benefits of Chitrakadi Vati for Digestion

• Dietary maricha stimulates pancreatic enzymes that improve digestion and reduce food transit time in the gastrointestinal tract.
• It also increases saliva production and gastric secretions and activates the salivary amylase enzyme.
• Maricha or piperine present in Chitrakadi vati on oral administration stimulates the release of bile acids from the liver, which are important in the digestion and absorption of lipids⁶. 

7. Benefits of Chitrakadi Vati for Managing Cholesterol

• Maricha inhibits cholesterol absorption while increasing cholesterol transporter protein translocation.
• It also improves digestion by assisting in the breakdown of bigger fat molecules into more easily digestible simple molecules and preventing fat storage in the body⁶. 

8. Benefits of Chitrakadi Vati Due to Anti-diarrhoeal Activity

• The antidiarrhoeal effects of maricha extract were studied⁶ in rats at various doses.
• The extract was shown to have considerable anti-diarrhoeal, anti-motility, and anti-secretory activity due to the presence of alkaloids in maricha. 

9. Benefits of Chitrakadi Vati in Managing Blood Clotting

• The effect of ginger extract on platelet thromboxane-B₂ and prostaglandin-E₂ synthesis was studied in rats.
• Oral administration of ginger at high doses is significantly effective in reducing serum prostaglandin-E₂ and thromboxane-B₂ levels.
• According to the findings, ginger can be employed as an anti-thrombotic and anti-inflammatory agent⁷. 

10. Benefits of Chitrakadi Vati for Gastrointestinal Tract

• Traditional medicine has long employed the powdered rhizome of ginger to relieve the symptoms of gastrointestinal tract ailments.
• According to a study⁷ in mice, the extract of ginger and its components improved the gastrointestinal emptying of the charcoal meal.
• In humans, ginger has been shown to help prevent postoperative nausea and vomiting while not affecting stomach emptying. 

11. Benefits of Chitrakadi Vati as an Antioxidant

• Several studies have revealed that ginger has potent antioxidant effects.
• The antioxidant effect of ginger has been proposed as one of the key probable reasons for the plant’s protective properties against radiation toxicity and lethality, as well as a variety of poisonous substances and potential as an anti-ulcer drug⁷. 
• The extracts of the Asafoetida plant showed antioxidant activity in experimental animals.
• Results of the study showed a reduction of lipid peroxidation levels in the liver of rats⁸. 

12. Benefits of Chitrakadi Vati for Managing Obesity

• The effects of F. asafoetida on weight gain and fat build-up in diabetic patients were researched.
• It was shown to reduce body weight, abnormal fat, and adipocyte cell size.
• As a result, it will be regarded a viable therapy option for diabetes-induced obesity⁸. 

13. Benefits of Chitrakadi Vati Due to Immunomodulatory Activity

The extracts of chavya considerably boost lymphocyte proliferation, implying an immunomodulatory action, mainly through lymphocyte proliferation and natural killer cell activity activation⁹. 

In Ayurveda, Chitrakadi vati might help in reducing oedema in the legs and hands (extremities) caused due to ama dosha¹³.

Dr. Rajeev Singh, BAMS

How to Use Chitrakadi Vati?

Chitrakadi vati can be used as: 

• Chitrakadi vati extract¹ 
• Chitrakadi dutika (pills)¹⁰ 

Side Effects of Chitrakadi Vati

Some side effects are observed due to the following constituents of Chitrakadi vati: 

• Chitraka: Excessive use of the chitraka plant has toxic effects. Irritation burning of the tongue, throat, stomach and other body regions can be seen. It can also cause nausea, vomiting, dysuria, diarrhoea, burning sensation while urinating, a weak pulse, wrinkled skin, and cold skin¹¹. 
• Ginger: It may cause heartburn, mild diarrhoea, gastric irritation and allergy⁷. 
• Hing: Its extracts have been investigated and proven safe for everyday usage. Large doses of asafoetida can cause mouth swelling, digestive problems such as flatulence and diarrhoea, nervousness, and headaches⁸.  

Generally, according to Ayurveda, ama and vatta doshas can create joint pain. In such cases, Chitrakadi vati might be useful in reducing joint pain¹³.

Dr. Smita Barode, BAMS

Also Read: Green Chilli: Uses, Benefits, Side Effects and More!

Precautions to Take with Chitrakadi Vati

You should keep the following points in mind: 

• In pregnancy, the utilisation of chitraka plants can irritate pelvic organs and ultimately cause abortion¹¹. 
• The gum of closely related species of Hing may irritate the skin and stomach, resulting in dermatosis¹². 
• Because it affects the menstrual cycle and is an abortifacient, Hing should not be used during pregnancy or lactation^8,12. 
• Foetal haemoglobin is oxidised with asafoetida use, whereas adult haemoglobin is not. Children should not be given this medication since it may cause methaemoglobinemia¹². 

Also Read: Abhayarishta: Uses, Benefits & How to Use It

Frequently Asked Questions (FAQs)

References

1. Kumar A, Deepa L, Lakshman K, Satish KV, Chandra Shekar KB, Narayan Swamy VB, et al. Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats. Pharmacologyonline [Internet]. 2007 [cited 2022 Feb 28];1:420-3. Available from: https://pharmacologyonline.silae.it/files/archives/2007/vol1/44_Kumar.pdf
2. Khanvilkar V, Patil L, Kadam V. Standardization of Chitrakadi Vati: An Ayurvedic Polyherbal Formulation. Int J Pharm Sci Drug Res [Internet]. 2014 [cited 2022 Feb 28];6(4):303-9. Available from: https://www.ijpsdr.com/index.php/ijpsdr/article/view/359/323
3. Shukla K, Karunagoda K, Sata N, Pandya MA. Evaluation of the role of Chitrakadi Vati in the management of Bandhyatva w.s.r to anovulation (as a consequence of unruptured follicle). AYU [Internet]. 2009 [cited 2022 Feb 28];30(4):392-6. Available from: https://www.ayujournal.org/temp/Ayu304392-5572047_152840.pdf
4. Chandran A, Mahadevan L, Nisha MG. Clinical Efficacy of Chitrakadi Gutika in Non Alcoholic Fatty Liver Disease-A Case Study. Int J AYUSH Case Reports [Internet]. 2021 [cited 2022 Feb28];5(4):237-41. Available from: https://www.ijacare.in/index.php/ijacare/article/view/250/203
5. Shukla B, Saxena S, Usmani S, Kushwaha P. Phytochemistry and pharmacological studies of Plumbago zeylanica L.: a medicinal plant review. Clin Phytosci [Internet]. 2021 [cited 2022 Feb28];7(1):34. Available from: https://clinphytoscience.springeropen.com/track/pdf/10.1186/s40816-021-00271-7.pdd
6. Saleem A, Naureen I, Naeem M, Tasleem G, Ahmed H, Farooq U. Therapeutic Role of Piper Nigrum L (Black Pepper) and Pharmacological Activities. Sch Int J Biochem [Internet]. 2022 [cited 2022 Feb 28];5(1):15-21. Available from: https://saudijournals.com/media/articles/SIJB_51_15-21.pdd
7. Ali BH, Blunden G, Tanira MO, Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chem Toxicol [Internet]. 2008 [cited 2022 Feb 28];46(2):409-20. Available from: https://sci-hub.st/10.1016/j.fct.2007.09.085
8. Amalraj A, Gopi S. Biological activities and medicinal properties of Asafoetida: A review. J Trad Complementary Med [Internet]. 2017 [cited 2022 Feb 28];7(3):347-59. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506628/
9. ) Islam MT, Hasan J, Snigdha HS, Ali ES, Sharifi-Rad J, Martorell M, et al. Chemical profile, traditional uses, and biological activities of Piper chaba Hunter: A review. J Ethnopharmacol [Internet]. 2020 [cited 2022 Feb 28];257:112853. Available from: https://pubmed.ncbi.nlm.nih.gov/32283191/
10. Chetty KM. Pharmaceutical studies and therapeutic uses of Plumbago zeylanica L. roots (Chitraka, Chitramulamu). Ethnobotanical Leaflets [Internet]. 2006 [cited 2022 Feb28];10:294-304. Available from: https://www.researchgate.net/publication/215649528_Pharmaceutical_Studies_and_Therapeutic_Uses_of_Plumbago_Zeylanica_L_Roots_Chitraka_Chitramulamu
11. ) Choudhary S, Kaurav H, Chaudhary G. Citraka (Plumbago zeylanica): A Potential Rejuvenator.Int J Res Appl Sci Biotechnol [Internet]. 2021 [cited 2022 Feb 28];8(2):202-12. Available from: https://www.researchgate.net/publication/350798692_Citraka_Plumbago_zeylanica_A_Potential_Rejuvenator
12. Duke JA. Handbook of medicinal herbs. CRC press; 2002 Jun 27 [cited 2022 Feb 28]; Page No: Available from: https://www.enpab.it/images/2018/James_A.Duke-_Handbook_of_Medicinal_Herbs.pd
13. Parihar BK, Kadibagil VR, Ganti BY. Role of Chitrakadi Vati in Grahani Roga. Int Ayurvedic Medical J. 2016;4(2):121–124. Available from: https://www.researchgate.net/publication/348704184_ROLE_OF_CHITRAKADI_VATI_IN_GRAHANI_ROGA

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

14

0

Nirgundi: Benefits, Uses, Side Effects & More!

Introduction

Nirgundi is an Ayurvedic medicine made from the dried leaves of Vitex negundo (Family Verbenaceae), a large aromatic shrub or small tree up to 4.5 m in height, common throughout the country to an altitude of 1500 m in the outer Himalayas¹. It is commonly known as Five-leaved chaste trees, which is a large family of herbs, shrubs, and trees, comprising about 75 genera and nearly 2500 species².

Common names of Vitex Negundo include Nirgundi and Sindhuvara in Sanskrit. Nirgundi is already in clinical use in traditional systems of medicine including Ayurveda, Unani, and Siddha for the management of pain, headache, inflammation, leukoderma, enlargement of spleen, rheumatoid arthritis, gonorrhoea, bronchitis, fever, cold and cough². The leaves of V.negundo have been reported to possess pesticidal and antifungal properties².

The Sanskrit word for Vitex negundo, a plant commonly known as nirgundi, carries a meaningful translation. ‘Nirgundi’ literally translates to ‘that which protects the body from diseases.’ This herb holds significance in Ayurvedic medicine, as it is mentioned in all of the Ayurvedic Samhitas, which are ancient texts that form the foundation of Ayurveda⁵.

Dr. Siddharth Gupta, B.A.M.S M.D (Ayu)

Chemical Constituents of Nirgundi Plant

Nirgundi contains at least 0.25 percent of negundoside and 1.0 percent of agnuside when assayed¹. The following table contains the chemical components present in the Nirgundi plant: 

• Leaves-  Vitamin-C, artemetin, terpinen-4-ol, α-terpineol, sabenine, globulol, spathulenol, β-farnesene, farnesol, carotene, casticin, 5-hydroxy-6,7,8, 4′-tetramethoxy (gardenin B), linalool, stearic acid, 5-hydroxy-3,6,7,3′, 4′-pentamethoxy flavone, 5-hydroxy-3,7,3′, 4′-tetramethoxy flavones, betulinic acid, ursolic acid. 
• Seeds- β-sitosterol, p-hydroxybenzoic acid, 5-oxyisophthalic acid, artemetin, vitedoin A, vitedoamine A, vitedoin B, 2β,3α-diacetoxyoleana-5, 12-dien-28-oic acid, 3β-acetoxyolean-12-en-27-oic acid, n-tritriacontane, n-hentriacontane, n-pentatriacontane, ß- sitosterol 
• Stem and bark- 3,6,7,3′,4′-Pentamethoxy-5-Oglucopyranosylrhamnoside, vitexin cafeate, 4′-O-methyl myricetin- 3-O-[4′-O-β-D-galactosyl]-β-Dgalactopyranoside, Î²-amyrin, epifriedelinol, oleanolic acid, p-hydroxybenzoic acid, β-sitosterol. 
• Roots- Vitexin and isovitexi, vitexoside, negundin A, negundin B, 6-hydroxy-4-(4-hydroxy-3-methoxy)-3-hydroxymethyl-7-methoxy-3,4-dihydro-2-naphthaledehyde, 2β,3α-diacetoxyoleana-5,12-dien-28-oic acid. 

Potential Uses of Nirgundi

The leaves of nirgundi have antibacterial, laxative, antioxidant, anticonvulsant, hypoglycaemic, and anti-inflammatory properties². The roots, barks, and fruits too have medicinal properties. Roots of nirgundi are one of the ingredients of the herbal formulation called ‘Dashamularishta’, used in the management of colitis, dysentery, diarrhoea, flatulence, fever, vomiting, and colic². The leaves contain alkaloid nisindine, flavonoids like flavones, luteolin-7-glycoside an essential oil, and constituents like vitamin C,  and carotene that account for different biological actions².

Benefits of Nirgundi

1. Benefits of Nirgundi for Infections

•  Nirgundi essential oil showed  antibacterial activity against B. subtilis, S. aureus, E. coli, and P. aeruginosa².
• The phytoconstituents d-guaiene, germacrene D, and hexadecenoic acid found in nirgundi are responsible for this anti-bacterial activity².  
• The leavd extracts possesses a new flavone glycoside, which has antifungal activity against Cryptococcus neoformans and Trichophyton mentagrophytes^2,3.

2. Benefits of Nirgundi for Pain

• The anti-inflammatory and pain suppressing activities of fresh leaves of nirgundi are attributed to prostaglandin synthesis inhibition².
• When tested in an animal model, the pain relieving activity of extract of V. negundo was compared with that of aspirin and meperidine.
• The study concluded that the Nirgundi leaves showed strong analgesic activity and may be used as an adjuvant therapy with standard analgesics³.

3. Benefits of Nirgundi for Liver

• The extracts of V. negundo seeds decreased the serum levels of aspartate transaminase and alanine transaminase³.
• The alcoholic seed extract also showed protective action on the liver against Carbon-tetrachloride(CCL4)-induced liver toxicity³.

4. Benefits of Nirgundi for Arthritis

• The heated leaf is used for managing rheumatoid arthritis-related pain and sprains.
• The oil prepared from the leaves can also be used³. 

5. Benefits of Nirgundi for Lungs

Nirgundi root decoction can be used for managing bronchitis and asthma^2,3. 

6. Benefits of Nirgundi for Diabetes

The leaf extracts of Vitex Negundo were reported for their anti-hyperglycemic activity in animals^2,3.

7. Benefits of Nirgundi for Wounds

Washing the wounds with nirgundi leaves extract can aid in cleaning infected ulcers³.

8. Benefits of Nirgundi for Skin

• Nirgundi leaf juice may be beneficial in managing bacterial and parasitic skin infections.
• Nirgundi seeds are used to deal with skin diseases and leprosy⁴.

9. Benefits of Nirgundi as an Antioxidant

• The water-soluble constituents of Vitex negundo possess potent antioxidant activities.
• Human studies might demonstrate its efficacy in humans^2,3.

Nirgundi, a versatile plant, has an amazing mosquito-repellent quality! During the rainy season, the leaves of nirgundi are burned in a fire, that may create a smoky shield that keeps mosquitoes and insects away from both animals and humans⁵.

Dr. Rajeev Singh, BAMS

Also Read: Nutmeg (Jaiphal): Uses, Benefits, Precautions & More!

How to Use Nirgundi Plant?

The following parts of the Nirgundi plant can be used: 

• Leaves: Nirgundi leaves can be boiled with water and the vapors can be inhaled. Nirgundi leaves can be ground to a paste and applied to the forehead to relieve headaches³.

• Flowers: Flower extracts of Nirgundi may be used in the management of fever, diarrhoea, and liver complaints³.

• Seeds: The seeds can be used with sugarcane or vinegar for the management of swellings. Powdered seeds can be used in the management of spermatorrhea and serve as an aphrodisiac when used along with dry ginger and milk⁴. The seeds can be made into a paste and used with salt and pepper for applying on fractures³. 

• Roots: Root powder, the tincture can be used for managing dysentery. The powdered root is used for anthelmintic properties. Root extract can be dissolved in tender coconut water for a week to suppress kidney problems³.

• Fruit: The dried fruit powder can be taken orally with roasted common salt and warm water for dealing with menstrual disorders, urinary disorders, and indigestion³.

Your Ayurvedic physician will prescribe you the form and dose as per your needs. 

Dry nirgundi leaves have a traditional use of being placed with stored woollen garments. This is because the leaves have properties that repel insects and worms, which may help protect the woollen items from damage⁵.

Dr. Smita Barode, B.A.M.S, M.S.

Also Read: Suhaga: Uses, Benefits, Precautions & More!

Precautions to Take With Nirgundi

Keep the following points in mind: 

• People with hormone-dependent conditions such as endometriosis, fibroids, or cancers of the breast, uterus, and prostate should not take Nirgundi.  
• It is not recommended during pregnancy and breastfeeding mothers for lack of safety studies.⁴ 

Also Read: Kaunch Beej – Uses, Benefits & Side Effects

Frequently Asked Questions (FAQs)

References

1. The Ayurvedic Pharmacopoeia of India, 1st edition, Part I, Volume IX. Delhi (IN): Government of India, Ministry of Health and Family Welfare, Department of Indian Systems of Medicine & Homoeopathy. Monographs (Extracts). Nirgundi. Available from: https://www.ayurveda.hu/api/API-Vol-1.pdf

2. Kantesh M Basalingappa, Vinutha T, Gopenath TS, et.al. Medicinal Values and Pharmacological Activities of Vitex Negundo LInn.  Journal of Global Trends in Pharmaceutical Sciences. 2020. II (1) 7579-7589. ISSN –2230-7346. Available from: https://www.jgtps.com/admin/uploads/ksM8L5.pdf

3. Harikesh Mourya, Vikas Rao. The Favorable Role of Alkaloids from Vitex negundo in the Management of Human Ailments. Annals of Clinical Pharmacology and Toxicology. 2019, Volume 1. Article 1007. Available from https://www.researchgate.net/publication/301516186_Vitex_negundo_Medicinal_Values_Biological_Activities_Toxicity_Studies_Phytopharmacological_Actions [PDF]  

4. SC Ahuja, Siddharth Ahuja, Uma Ahuja. Nirgundi (VItex negundo) – Nature’s GIft to Mankind. Asian Agri-History Vol.19. No 1. 2015 (5-32). [Internet] [Available from – https://www.asianagrihistory.org/pdf/volume19/nirgundi-natures-gift-to-mankind.pdf  
5. Ahuja SC, Ahuja S, Ahuja U. Nirgundi (Vitex negundo) – Nature’s Gift to Mankind. Asian Agri-History. 2015 Jan-Mar;19(1):5-32. Available from: https://www.asianagrihistory.org/pdf/volume19/nirgundi-natures-gift-to-mankind.pdf

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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8 Powerful Ayurvedic Herbs With Their Great Benefits

Introduction

Ayurveda is an ancient Indian medical system. Ayurveda means the science or knowledge of life, where ‘Ayur’ means life and ‘Veda’ means knowledge.  

The Ancient and Traditional practice of Ayurvedic is 5,000 years old and works on three basic three principles or doshas (Vata, Pitta, and Kapha) and ayurveda practice is based on three classical texts – the Charaka Samhita, the Sushruta Samhita, and the Ashtanga Hridaya which were written in Sanskrit over 2,000 years ago and are collectively known as the Great Trilogy. 

Ayurveda takes a holistic approach to health, focusing on lifestyle, diet, and natural substances. It is important to note that while Ayurveda is a recognised traditional system of healthcare in India, its treatments should be approached responsibly and under the guidance of qualified practitioners. Individuals are encouraged to consult registered medical professionals for the diagnosis and management of any medical condition¹. 

The Role of Ayurvedic Herbs

Ayurvedic herbs are an integral part of the Ayurvedic medicine system. Since ancient times, these herbs have been used to help manage different diseases, promote mental clarity, boost immunity, and support healthy skin. In Ayurvedic practice, attention is given to the person as a whole, addressing the mind, body, and lifestyle rather than focusing solely on the symptoms of a condition. A wide range of herbs are used in Ayurveda to treat illnesses, with active ingredients derived from leaves, roots, flowers, and bark. These herbs are selected with the intention of promoting internal balance and supporting the body’s natural functions².  

Manjistha, for instance, may be beneficial in managing bone-related conditions. A 2020 study found that the root of Manjistha contains a compound that may be effective as a phytomedicine in the treatment of bone disorders¹⁶.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Benefits of Ayurvedic Herbs

The Ayurvedic system offers a traditional, holistic approach to wellness, focusing on balance and overall health rather than isolated symptoms. Some of the benefits of ayurvedic herbs are as follows: 

• Supports the balance among the doshas (Vata, Pitta, and Kapha), which is considered important for overall well-being in traditional Ayurvedic understanding³.   
• Considers the individual as a whole, and any supportive measures used are selected with the aim of promoting general health, not solely addressing isolated symptoms³.   
• Centres around lifestyle, diet, and plant-based preparations, and is considered by some to be gentler in its approach⁴.   
• Improves vitality and provides strength, in line with the system’s holistic philosophy⁴.   
• Emphasises maintaining internal balance, which is believed to help support the body’s natural defences⁴. 

Some of the Best Ayurvedic Herbs

The following ayurvedic herbs have been traditionally valued for their various properties and uses over many years. Below is an overview of some commonly known herbs and their traditionally associated benefits: 

1. Ashwagandha

Ashwagandha is a well-known herb in traditional Ayurvedic practice, used for various purposes over many centuries. The name ‘Ashwagandha’ is derived from Sanskrit, where ‘Ashva’ means horse and ‘Gandha’ means smell, suggesting, in traditional texts, the vitality and strength associated with a horse. 

It is sometimes referred to as ‘Winter Cherry’ or ‘Indian Ginseng’, and is particularly noted in Ayurveda for its traditional association with supporting the body’s resilience and overall vitality. The roots of the Ashwagandha plant are commonly used in Ayurvedic preparations⁵. The benefits of Ashwagandha are as follows: 

• Boosts immune system⁵ 
• Decreases stress⁶ 
• Helps with memory and cognition⁶ 
• Improve sleep patterns⁶
• Helps to maintain normal testosterone levels in males⁶ 
• May improve fertility⁶
• Helps improve heart health⁶
• Helps improve thyroid health⁶

Ashwagandha is a versatile herb and is traditionally available in various forms, including powders, tablets, and liquid extracts. It may be taken with or without food, depending on individual preference and practitioner guidance. 

Caution: The use of Ashwagandha during pregnancy is not generally recommended unless under the supervision of a qualified medical professional. Individuals with thyroid-related conditions, particularly hyperthyroidism, should seek advice from a healthcare practitioner before using Ashwagandha or related preparations. 

2. Brahmi

Brahmi, also known as Bacopa monnieri, is a well-regarded herb in traditional Ayurvedic practice. It has been traditionally used for its association with supporting cognitive health and mental clarity. The plant’s leaves are considered particularly valued in Ayurvedic literature and are often used in various preparations  

Brahmi is also noted in traditional sources for its natural antioxidant and soothing properties, which have contributed to its continued use over generations. 

Below are some traditionally associated uses of Brahmi⁷: 

• Supports mental health and cognitive well-being   
• Helps improve memory, concentration, and learning 
• Helps with nervous system function 
• Helps reduce stress and depression 
• Can help calm the mind 
• May reduce the symptoms of attention deficit hyperactivity disorder (like hyperactivity). 
• Recognised for its antioxidant content, it may support general cellular health 
• Traditionally used in formulations aimed at promoting healthy skin and hair by supporting internal balance 

3. Shatavari

Shatavari also known as ‘queen of herbs’. is a medicinal herb with many health benefits. The presence of saponins contributes to its antioxidant properties. Shatavari is traditionally associated with supporting immune function and female reproductive health, as described in classical Ayurvedic texts.  

Here are some benefits of Shatavari⁸: 

• May improve immunity  
• May reduce inflammation 
• May be effective in alleviating respiratory symptoms 
• Helps relieve acidity symptoms 
• Helps with stomach and intestinal ulcers 
• Helps manage blood sugar levels 
• Helps with anti-aging changes in the skin 

4. Liquorice

Liquorice has been used since ancient times in various traditional systems of medicine, including those of India, Greece, and Egypt. Owing to its naturally sweet flavour, it continues to be used in a range of preparations such as herbal teas, confectionery, capsules, and liquid extracts. 

The benefits of Liquorice are as follows^9,10: 

• Helps provide relief from acidity, stomach ulcers, and food poisoning 
• Helps with cold and cough 
• Helps reduce stress 
• Acts as an anti-inflammatory, anti-spasmodic, and anti-microbial agent 
• Helps reduce hair fall and to prevent dandruff 
• Beneficial in prostate gland problems

Also Read: Dashmularishta: Uses, Benefits, Side Effects & More!

5. Neem

Neem has been mentioned extensively in classical Ayurvedic texts and is included in a large number of traditional formulations. It is often associated with supporting general hygiene, skin care, and internal balance in Ayurvedic practice¹¹.  

The benefits of neem are as follows: 

• Neem has antiseptic, anti-microbial, and antifungal properties¹¹.   
• Potent blood purifier and detoxifier¹¹.
• Treat eczema, and skin diseases¹¹.
• Helps to reduce fever, especially malarial fever¹¹.
• Helps maintain oral hygiene and prevent dental caries and infections 
• Beneficial for the hair and helps to control dandruff.   

Licorice root has been traditionally studied for its potential benefits in supporting oral hygiene. Some research¹⁷ suggests that compounds found in licorice may help in maintaining dental cleanliness and overall oral health. However, its use should be approached with caution and under the supervision of a qualified healthcare professional.

Dr. Rajeev Singh, BAMS

6. Manjistha

Manjistha is particularly noted for its long-standing use in Ayurvedic practices related to circulatory and skin wellness¹². The benefits of Manjistha are as follows; 

• Helps boost immunity 
• Helps improve complexion and clear acne¹²   
• Helps improve memory and learning ability   
• Helps with allergic conditions  

7. Amla

Amala is highly regarded in Ayurvedic tradition as a nourishing and revitalising fruit. It has naturally occurring antioxidants and helps support the body’s internal balance. The benefits of amala are as follows¹³: 

• Supports immunity 
• May strengthen the heart 
• Beneficial for hair, skin, and eyes 
• May help reduce high blood sugar levels 
• May provide relief from acidity  

Some studies¹⁸ suggest that Amla contains antioxidants and phytonutrients that may help support cognitive health. Its naturally high Vitamin C content is also believed to play a role in maintaining normal brain function.

Dr. Smita Barode, B.A.M.S, M.S.

8. Haritaki

Haritaki is known as the ‘king of herbs’ in Ayurveda. In traditional Ayurvedic belief, Haritaki is associated with promoting internal balance and supporting clarity of mind, vitality, and overall well-being. The benefits of Haritaki are as follows: 

• Strengthens the vital functions of the body, such as strong digestion¹⁴, nutrient absorption, and elimination. 
• May reduce cholesterol levels¹⁵  
• Helps prevent lung infections¹⁵
• May support eye health¹⁵

Also Read: Black Salt: Uses, Benefits, Side Effects, Precautions & More!

Conclusion

Ayurveda offers a time-tested, holistic approach to health, rooted in balance and natural practices. When used under the guidance of qualified professionals, Ayurvedic herbs may support general well-being as part of a balanced lifestyle. 

Also Read: Tamarind (Imli): Uses, Benefits, Side Effects and More!

References

1. Sharma H. Ayurveda: Science of life, genetics, and epigenetics. Ayu. 2016 Apr-Jun;37(2):87-91. doi: 10.4103/ayu.AYU_220_16. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5688840/  
2. Shukla SD, Bhatnagar M, Khurana S. Critical evaluation of ayurvedic plants for stimulating intrinsic antioxidant response. Front Neurosci. 2012 Jul 26;6:112. doi: 10.3389/fnins.2012.00112. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3405414/  
3. Mills PJ, Peterson CT, Wilson KL, Pung MA, Patel S, Weiss L, Kshirsagar SG, Tanzi RE, Chopra D. Relationships among classifications of ayurvedic medicine diagnostics for imbalances and western measures of psychological states: An exploratory study. J Ayurveda Integr Med. 2019 Jul-Sep;10(3):198-202. doi: 10.1016/j.jaim.2018.02.001. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6822152/  
4. Patibandla S, Gallagher JJ, Patibandla L, Ansari AZ, Qazi S, Brown SF. Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health. Cureus. 2024 Feb 29;16(2):e55240. doi: 10.7759/cureus.55240. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10981444/  
5. Mikulska P, Malinowska M, Ignacyk M, Szustowski P, Nowak J, Pesta K, et al. Ashwagandha (Withania somnifera)-Current Research on the Health-Promoting Activities: A Narrative Review. Pharmaceutics. 2023 Mar 24;15(4):1057. doi: 10.3390/pharmaceutics15041057. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10147008/  
6. Guo S and Rezaei MJ (2024) The benefits of ashwagandha (Withania somnifera) supplements on brain function and sports performance. Front. Nutr. 11:1439294. doi: 10.3389/fnut.2024.1439294. Available from: https://www.researchgate.net/publication/382845577_The_benefits_of_ashwagandha_Withania_somnifera_supplements_on_brain_function_and_sports_performance  
7. Mathur D, Goyal K, Koul V, Anand A. The Molecular Links of Re-Emerging Therapy: A Review of Evidence of Brahmi (Bacopa monniera). Front Pharmacol. 2016 Mar 4;7:44. doi: 10.3389/fphar.2016.00044. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4778428/  
8. Alok S, Jain SK, Verma A, Kumar M, Mahor A, Sabharwal M. Plant profile, phytochemistry and pharmacology of Asparagus racemosus (Shatavari): A review. Asian Pac J Trop Dis. 2013 Jun;3(3):242–51. doi: 10.1016/S2222-1808(13)60049-3. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4027291/  
9. Wahab S, Annadurai S, Abullais SS, Das G, Ahmad W, Ahmad MF, et al. Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology. Plants (Basel). 2021 Dec 14;10(12):2751. doi: 10.3390/plants10122751. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8703329/  
10. Lai S, Shi L, Jiang Z, Lin Z. Glycyrrhizin treatment ameliorates post-traumatic stress disorder-like behaviours and restores circadian oscillation of intracranial serotonin. Clin Exp Pharmacol Physiol. 2020 Jan;47(1):95-101. doi: 10.1111/1440-1681.13173. Available from: https://pubmed.ncbi.nlm.nih.gov/31494960/  
11. Reddy IVS, Palagani N. Neem (Azadirachta indica): A review on medicinal Kalpavriksha. Int J Econ Plants. 2022;9(1):59–63. Available from: https://www.researchgate.net/publication/358875244_Neem_Azadirachta_indica_A_Review_on_Medicinal_Kalpavriksha 
12. Meena V, Chaudhary AK. Manjistha (Rubia cordifolia) – A helping herb in cure of acne. J Ayurveda Holist Med [Internet]. 2015 Jun [cited 2025 Jun 2];3(2):11–17. Available from: https://www.researchgate.net/publication/302902410_ManjisthaRubia_Cordifolia-_A_helping_herb_in_cure_of_acne 
13. Shrivastava S, Kaur J, Mehraj M, Feroz F, Chawla J, Kumari S. Emblica officinalis (Amla): A comprehensive review of the miracle berry. Pharma Innov J. 2022;11(6):6–16. Available from: https://www.thepharmajournal.com/archives/2022/vol11issue6/PartA/11-6-187-801.pdf 
14. Babar TP, Gokhale V. Haritaki—An Ayurvedic literature review. Int J Sci Res. 2021;10(7):22. Available from: https://www.researchgate.net/publication/362504395_HARITAKI-AN_AYURVEDIC_LITERATURE_REVIEW 
15. Ram TS, Srinivasulu B, Narayana A. Pragmatic usage of Haritaki (Terminalia chebula Retz): an Ayurvedic perspective vis-à-vis current practice. Int J Ayur Pharma Res. 2013;1(3):72–82. Available from: https://ijapr.in/index.php/ijapr/article/view/50

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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