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OMAD Diet: What It Is, How It Works, Benefits, and Side Effects

By Dr. Malavika Athavale +2 more

Join Health Talk by PharmEasy on WhatsApp

Introduction

Intermittent fasting has gained widespread attention in recent years, with various approaches being discussed across health platforms. Among these, OMAD, which stands for “One Meal a Day”, has emerged as a popular pattern of eating. It is often described as a time-efficient approach that limits eating to one single meal a day and appeals to individuals seeking a structured routine or simplified meal planning.

omad

But what exactly does this “OMAD diet” lifestyle involve, and is it as simple as it sounds? Let’s dive into the mechanics of the OMAD diet, how it differs from standard fasting, and why it has become such a hot topic in the health and wellness community.

What is the OMAD Diet?

The OMAD diet is a structured form of intermittent fasting in which food intake is limited to one main meal a day. Unlike other fasting approaches that involve skipping certain meals or eating within a certain time window, OMAD concentrates daily calorie and nutrient intake into one single meal.


The fundamental concept of the OMAD diet is that, by limiting your food intake to a single hour, you instinctively lower your calorie consumption while providing your digestive tract with a nearly 23-hour period of rest.

How Does the OMAD Diet Work?

The one meal a day diet follows a 23:1 ratio, which breaks down as below:

  • The 23-Hour Fast: For 23 hours of the day, you consume zero calories. You are typically allowed to stay hydrated.
  • The 1-Hour Window: You consume your entire days’ worth of calories, vitamins, and nutrients in a single, one-hour window1.

After approximately 10 to 16 hours without food, the body exhausts its immediate sugar (glucose) stores and begins to break down fat for energy. As fat stores are utilised, the liver releases fatty acids called ketones into the bloodstream that serve as an alternative fuel source for the body2.

An OMAD diet plan may lead to an overall decrease in food intake, thus helping contribute to weight and fat loss.

Benefits of OMAD Diet

While it is a rigorous regimen, some researchers highlight several physiological and lifestyle OMAD diet benefits, such as:

1. Cardiovascular Protection

heart health

It may help reduce several risk factors for heart disease, including:


  • Lowering blood pressure: Studies show significant reductions in both systolic and diastolic blood pressure.
  • Improving lipid profile: Intermittent fasting may lead to decreased levels of total cholesterol, triglycerides, and LDL cholesterol.
  • Reducing atherosclerosis risk: By improving lipid levels and reducing inflammation, it helps slow the progression of plaque build-up in arteries3.

2. Metabolic Improvement

regulates blood sugar
  • Blood sugar control: Fasting helps lower blood glucose levels and improve insulin sensitivity, which may be beneficial for managing type 2 diabetes.
  • Metabolic switching: It triggers a shift from using glucose to using ketones and fatty acids for energy, a process known as intermittent metabolic switching (IMS)3.

3. Helps in Weight Loss

weight

OMAD is popular for weight loss3 because it’s much harder to overeat in just one hour than it is when you’re snacking and eating meals throughout the entire day.

  • Caloric deficit: Many individuals find it difficult to eat more than 1500 calories in one sitting, leading to an effortless caloric deficit.

4. Brain Health and Stress Resistance

stress
Image Source: freepik.com

When you fast, your body’s chemical changes help your brain cells work better and become tougher, making them more resistant to stress, injury, and illness3.

5. Anti-Inflammatory Effects

inflammaation

Fasting is seen to help reduce pro-inflammatory markers (biological parameters that indicate inflammation) like C-reactive protein (CRP), homocysteine, and interleukin-63.

6. Better Digestive Health

digestive system

Animal research suggests that longer fasting windows help lower overall bacteria levels, which is associated with better digestive health and a longer life4.

While the discipline required for OMAD diet is high, the combined benefits of mental clarity, digestive health, and effortless weight management make OMAD a compelling strategy for optimising health.

Side Effects of OMAD Diet

Some individuals may experience side effects due to the long fasting window in the OMAD diet. OMAD side effects include:

  • Headache
  • Lethargy
  • Mood swings
  • Dizziness
  • Polyuria
  • Low blood sugar
  • Constipation
  • Dehydration
  • Insomnia (sleeplessness)
  • Digestive issues5

In one study6 on normal weight individuals, fasting was associated with increased hunger and reduced fullness, higher blood pressure, changes in cholesterol levels, and decreases in red blood cell count, haemoglobin, and haematocrit in some participants.

Consult a physician to determine if an OMAD regimen is appropriate for you and to mitigate potential health risks.

What to Eat on the OMAD Diet?

When following a One Meal a Day diet, the goal is to pack an entire day’s worth of nutrients into a single sitting. Because you only have one opportunity to eat, the best foods to include in your meal are nutrient-dense, high-fibre foods that are rich in healthy fats and protein to keep you full and sustain your energy for the next 23 hours. Here are some foods you can include in the OMAD meal:

  • Whole Grains: To get the most nutritional value, at least half of your daily grain intake should be from whole grains. Unlike refined grains, whole grains retain the entire kernel, preserving the natural fibre and essential nutrients that are often stripped away during processing7.
  • Vegetables (e.g., Beans, Spinach and Kale): Plant-based foods, whether harvested from farms, gardens, or trees are packed with the essential nutrients (e.g., iron and zinc) and fibre your body needs. These natural sources provide lasting satiety and a consistent energy boost throughout the day7.
  • Dairy Foods: Low-fat and non-fat dairy such as milk, yogurt, and cottage cheese are excellent sources of vital nutrients like calcium, vitamin D, and potassium. While sugary beverages provide extra calories, these dairy products offer nutrient density that helps keep you feeling satisfied7.
  • Nuts: Nuts provide a powerful combination of protein, fibre, and healthy fats. However, because they are calorie-dense and easy to overeat, it is best to pre-portion your servings instead of eating directly from the bag. They can be served as a topper for salads and main courses7.
  • Fish and Meat: Prioritising lean protein sources like seafood (aiming for 225 g weekly), skinless poultry, and lean cuts of red meat significantly reduces your intake of saturated fats and calories while providing essential nutrients7.
  • Eggs: They contain almost every nutrient you need. They are an affordable, complete protein source and contain choline, which is important for liver function and metabolism8.

Ultimately, the key to a successful OMAD journey is prioritising quality over quantity. By choosing nutrient-dense whole foods, you ensure that your one meal provides the sustained energy and nourishment your body needs to thrive during the fasting hours.

Note: After ending the OMAD plan, a gradual return to normal diet can help you avoid symptoms like nausea, vomiting, heaviness in the abdomen, and bloating. During this transition period, you should consume nutrient-dense foods that are high in vegetables and proteins and low in carbohydrates1.

OMAD Sample Diet Plan

When following the One Meal a Day protocol, your single meal must be a “powerhouse” of nutrition. Because you aren’t eating for the other 23 hours, this meal needs to cover your daily requirements for protein, healthy fats, fibre, and micronutrients. Make sure you drink at least 2 litres of water per day. You may also drink herbal/calorie-free infusions (e.g., chamomile or mint tea), unsweetened tea or black coffee, and sugar-free electrolytes or supplements.

To maintain their current weight, an average woman typically requires 2,000 calories daily, while an average man needs 2,500. For those looking to lose approximately one pound per week, these targets should be reduced to 1,500 calories for women and 2,000 calories for men1,9.

Diet Plan for Non-Vegetarians

Menu Dessert Drink 
Grilled chicken breast (200g), roasted sweet potato (1 medium), mixed vegetables (broccoli, carrots, bell peppers), side salad with olive oil and lemon dressing Some mango slices Water or herbal tea 

Diet Plan for Vegetarians 

Menu Dessert Drink 
Quinoa (1 cup cooked), stir-fried tofu (150g), spinach, mushrooms, bell peppers, soy sauce and olive oil Fresh figs with honey and almonds Water or lemon tea 

Diet Plan for Vegans 

Menu Dessert Drink 
200 g tofu, Stir-fried vegetables of your choice (beans, mushroom etc.) in olive oil 0.5 cups white/brown rice Dark chocolate and mixed nuts Water or lemon tea 

This is a sample OMAD diet plan that you can customise to your preference. Feel free to add or remove items, but for the best results, ensure your total calorie intake remains within your target range.

Note: While you can schedule your daily meal at your convenience, some research suggests that an evening mealtime may yield the best outcomes.10 Regardless of when you eat, prioritise a balanced, nutrient-dense diet. Be sure to track your intake by checking food labels or using a reliable online calorie calculator.

Who Should Avoid the OMAD Diet?

While fasting can offer health benefits, it isn’t safe for everyone. It is essential to consult your doctor before starting, particularly if you:

  • Are under 25 years old.
  • Are currently pregnant or breastfeeding.
  • Use insulin or other medications to manage blood sugar.
  • Take prescriptions that must be consumed with food.
  • Have a history of seizure disorders.
  • Work night shifts or operate heavy machinery11.

Fasting significantly alters your body’s metabolic state. For those on medication, particularly for diabetes, fasting can lead to dangerous drops in blood sugar (hypoglycaemia).

When to Consult a Doctor?

It is normal to feel a little different when you change what you eat, but your body shouldn’t feel like it’s failing. Some symptoms, such as the following, are “warning signs” telling you that your diet is too stressful or missing the fuel you need to stay healthy.

  • Feeling weak or completely drained of energy.
  • Feeling lightheaded or unsteady on your feet.
  • Losing more weight than expected.
  • Getting sick often.
  • Developing very dry skin or hair and nails that break easily12,13.

If you notice any of these symptoms, please schedule an appointment with your doctor. They can help you adjust your plan to make sure you are reaching your goals safely and getting the nutrition your body needs to thrive.

Conclusion

The OMAD diet can be considered an effective tool for weight loss and metabolic discipline, particularly for healthy adults who prefer a simplified eating schedule and can manage long periods of hunger. It may work best for individuals looking to break through weight loss stalls or improve insulin sensitivity under medical supervision. However, because of its extreme nature, it is not a fit for all solution; its success depends entirely on the quality of nutrients consumed during that single hour and the individual’s ability to sustain the regimen without experiencing severe side effects.

Also Read: Calorie Deficit Diet: What Is It, How to Follow, Strategies and More!

Frequently Asked Questions (FAQs)

What are the 4 rules of OMAD Diet?

Here are the 4 rules to be followed when on a OMAD diet
Consume a single daily meal.
Consume at least 2 litres of water a day.
Prioritise nutrient-rich foods.
Refrain from unscheduled snacking1.

What is the best time of day for OMAD?

OMAD diet is flexible and depends upon your specific lifestyle demands but evidence indicates that timing your single meal in the evening may optimise metabolic outcomes10.

How to start OMAD diet for beginners?

Rather than jumping straight into a strict 23:1 schedule, beginners should ease into the process. Start with more flexible methods like 16:8 or the 5:2 approach to give your body time to adapt. This will help your body get used to the diet pattern14.

Do doctors recommend OMAD?

Doctors generally don’t recommend the OMAD diet because it’s very hard to get all your daily nutrients in just one sitting. If you aren’t strictly focused on nutrition, this eating pattern can cause health issues rather than solving them.

References

  1. Ciastek B, Kapłon K, Domaszewski P. A Comprehensive Perspective on the Biological Effects of Intermittent Fasting and Periodic Short-Term Fasting: A Promising Strategy for Optimizing Metabolic Health. Nutrients. 2025 Jun 20;17(13):2061. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC12250775/
  2. Collier R. Intermittent fasting: the science of going without. CMAJ. 2013 Jun 11;185(9):E363-4. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3680567/
  3. Malinowski B, Zalewska K, Węsierska A, Sokołowska MM, Socha M, Liczner G, Pawlak-Osińska K, Wiciński M. Intermittent Fasting in Cardiovascular Disorders-An Overview. Nutrients. 2019 Mar 20;11(3):673. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6471315/
  4. Catterson JH, Khericha M, Dyson MC, Vincent AJ, Callard R, Haveron SM, Rajasingam A, Ahmad M, Partridge L. Short-Term, Intermittent Fasting Induces Long-Lasting Gut Health and TOR-Independent Lifespan Extension. Curr Biol. 2018 Jun 4;28(11):1714-1724.e4. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5988561/
  5. Shalabi H, Hassan AS 4th, Al-Zahrani FA, Alarbeidi AH, Mesawa M, Rizk H, Aljubayri AA. Intermittent Fasting: Benefits, Side Effects, Quality of Life, and Knowledge of the Saudi Population. Cureus. 2023 Feb 7;15(2):e34722. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9998115/
  6. Stote KS, Baer DJ, Spears K, Paul DR, Harris GK, Rumpler WV, Strycula P, Najjar SS, Ferrucci L, Ingram DK, Longo DL, Mattson MP. A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults. Am J Clin Nutr. 2007 Apr;85(4):981-8. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC2645638/
  7. Diet-boosting foods [Internet]. Medlineplus. 2024 [cited 2026 Jan 20]. Available from: https://medlineplus.gov/ency/patientinstructions/000810.htm
  8. Myers M, Ruxton CHS. Eggs: Healthy or Risky? A Review of Evidence from High Quality Studies on Hen’s Eggs. Nutrients. 2023 Jun 7;15(12):2657. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10304460/
  9. Osilla EV, Safadi AO, Sharma S. Calories. [Updated 2022 Sep 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK499909/
  10. Meessen ECE, Andresen H, van Barneveld T, van Riel A, Johansen EI, Kolnes AJ, Kemper EM, Olde Damink SWM, Schaap FG, Romijn JA, Jensen J, Soeters MR. Differential Effects of One Meal per Day in the Evening on Metabolic Health and Physical Performance in Lean Individuals. Front Physiol. 2022 Jan 11;12:771944. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8787212/
  11. To fast or not to fast [Internet]. NIH News in Health. [cited 2026 Jan 20]. Available from: https://newsinhealth.nih.gov/2019/12/fast-or-not-fast
  12. Malnutrition. Food and Nutrition [Internet]. Medlineplus. 2025 [cited 2026 Jan 20]; Available from: https://medlineplus.gov/malnutrition.html
  13. Weight loss – unintentional [Internet]. Medlineplus.gov. 2025 [cited 2026 Jan 20]. Available from: https://medlineplus.gov/ency/article/003107.htm
  14. A beginner guide to Intermitted fasting [Internet]. Umich.edu. [cited 2026 Jan 20]. Available from: https://sph.umich.edu/pursuit/2019posts/beginners-guide-to-intermittent-fasting.html

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information and disclaims any liability arising thereof.

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