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Chayote: Uses, Benefits, Side Effects & More  

Introduction

Chayote, scientifically known as Sechium edule, is a climbing plant belonging to the Cucurbitaceae family. Initially grown in Mexico and Guatemala, it was later introduced to the United States, Europe, Africa, China, and South-Asian countries. Nowadays, it is grown throughout the world in tropical and subtropical areas1

There are two major varieties of chayote plants, namely, the commercial variety and the wild type.1 Commonly chayote is known by different names such as vegetable pear, cho cho, chow-chow, sayote, pear squash, christophene, chuchu, guisquil, and iskus2

The plant’s edible parts are its fruits, stems, leaves, and roots. Chayote fruits are bright green and pear-shaped. There are many medicinal benefits of chayote owing to the bioactive compounds such as sterols, cucurbitacins and polyphenol compounds present in it1.  

Chayote Nutritional Value

Chayote has high nutrient value and is loaded with essential vitamins, minerals, fibers, and antioxidants. According to the US Department of Agriculture, the nutritional value of 100g of Chayote is as follows4:   

Potential Uses of Chayote for Overall Health

Existing studies suggest that chayote may offer the following potential benefits as a part of overall health:   

1. Potential Uses of Chayote for the Heart Health

Diets high in saturated fats can lead to fat build-up in the arteries, making it harder for the heart to pump blood efficiently. Chayote is low in fat and contains fibre and antioxidants, which may support heart health by helping to manage cholesterol levels as part of a balanced diet.  

A study8 found that extracts of Chayote help in the treatment of heart diseases by influencing the function of the smooth muscles of the arteries. Additionally, chayote is rich in fibres, and studies have shown that dietary fibres may prevent heart diseases9. However, if you have a heart condition, don’t replace your medications with chayote. It is best to consult a doctor and seek treatment accordingly.  

2. Potential Uses of Chayote for Diabetes

Diabetes is a medical condition in which blood has high levels of sugar. A review study found that the natural antioxidants in the vegetables like chayote may maintain glucose balance in the body and reduce sugar spikes after meals10. Additionally, the rich fibrous content of the chayote may help in managing blood sugar levels by slowing down the absorption of carbohydrates, resulting in reduced blood sugar levels after eating.  The chayote extracts may reduce blood sugar levels3. Consult a doctor to know if consuming chayote is right for you in supporting diabetes management.   

3. Potential Uses of Chayote in Pregnancy 

Women require specific nutrients like folate, iron, calcium, and essential vitamins to support a healthy pregnancy2. Chayote is a good source of folate, a vital nutrient during pregnancy that supports the healthy development of the baby’s brain and spinal cord. Research has shown that adequate folate intake may help reduce the risk of premature delivery and neural tube defects. Including chayote as part of a balanced diet may contribute to a healthy pregnancy. It can also help in lowering blood pressure in pregnant women; however, it is important to consult a healthcare professional rather than relying on self-medication11,12.  

4. Potential Uses of Chayote in Cancer 

Cancer is a medical condition where the body’s cells abnormally multiply, affecting its normal functioning. A study5 found that chayote may inhibit the multiplication of cancerous cells and promote cell death. Studies13 have also found that chayote fruits may help in the treatment of acute myeloid leukemia. Additionally, the chayote leaf extracts may inhibit the multiplication of breast cancer cells14. However, if you suspect cancer, instead of self-medicating, you should consult a doctor to understand chayote leaves’ health benefits and seek treatment accordingly.   

5. Potential Uses of Chayote for Anti-ageing  

Antioxidants may protect the body against cellular damage and reduce inflammation. A study has shown that free radicals may damage the body cells, reduce the body’s functioning over time, and accelerate ageing. Studies15 show that antioxidants from chayote can protect the cells from harmful effects of UV rays, reduce cell damage, and slow down the signs of ageing16. Chayote is rich in antioxidants and vitamin C and may benefit the skin by promoting collagen production that may reduce the visible signs of ageing such as wrinkles, fine lines, and pigmentations1. However, you should always consult a doctor instead of self-medicating to get chayote leaves benefits.   

6. Potential Uses of Chayote in Fatty Liver 

Fatty liver disease occurs when excessive fat accumulates in the liver, affecting its normal function. Some studies have indicated that extracts from chayote may help protect liver tissue by reducing fat deposition. While these findings are promising, further research is needed, and dietary changes should always be discussed with a healthcare professional7. More research is required to understand how chayote squash benefits liver functioning. If you have a fatty liver, you should consult a doctor instead of self-medicating. 

7. Other Potential Uses of Chayote

Other potential uses of chayote squash vegetable are as follows:   

In traditional medicine, decoctions made from the leaves or fruit of chayote have been used for their potential diuretic properties. They have been traditionally applied to help relieve burning sensations during urination, support kidney health, and manage certain respiratory discomforts. However, these uses are based on traditional practices, and scientific evidence is limited. Anyone considering such remedies should consult a qualified healthcare professional8

Chayote fruit is rich in vitamin A and E, both of which are essential for normal bodily functions. Vitamin A may support good vision, reproductive health, and the health of your blood, while vitamin E might be crucial for maintaining a healthy brain and glowing skin19.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Chayote?

Chayote can be used in the following ways:  

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.     

Side Effects of Chayote

No significant side effects have been scientifically documented in relation to the moderate consumption of chayote as part of a normal diet. It is well-tolerated by most people and is not known to cause adverse effects when properly prepared and consumed in typical amounts. 

Precautions to Take with Chayote

General precautions must be followed while consuming chayote. Here is a list of a few precautions.    

Also Read: Ber Fruit (Jujube): Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

There is not enough evidence on the interaction of the chayote extracts with other drugs. Further studies are required. Therefore, you must consult your doctor if you are on any other medication before consuming chayote.    

There is a traditional belief that chayote leaves may help in the natural elimination of kidney stones. They have been used in some cultures with the view that their properties might support the breakdown of kidney stones. However, scientific research on this specific use is currently limited19. It is important to consult a medical professional for proper diagnosis and treatment of kidney stones rather than relying solely on traditional remedies.

Dr. Rajeev Singh, BAMS

Chayote Recipes

Chayote recipes can be enjoyed in both savoury and sweet dishes. Here are a few chayote recipe ideas to inspire your culinary creativity: 

1. Chayote Salad

Make a refreshing salad by thinly slicing chayote and mixing it with your favourite vegetables, such as tomatoes, onions, and bell peppers. Toss the salad with a zesty vinaigrette dressing for a crisp and healthy side dish. 

2. Stuffed Chayote

Stuffed chayote is a flavourful and satisfying dish in which chayote halves are filled with a seasoned mixture, commonly containing ground meat, vegetables, and herbs. The filled chayotes are then baked or cooked until tender, allowing the mild flavour of the vegetable to blend beautifully with the savoury stuffing. This dish serves as a hearty, protein-rich main course and a wholesome addition to any meal. 

3. Chayote Fries

Cut chayote into strips, season with your preferred spices, and bake or air-fry for a nutritious alternative to traditional potato fries. Sliced chayote is seasoned and baked until it becomes crisp and golden brown, offering a delightful snack or side dish with a unique flavour and texture. These chayote fries are a healthier choice for those looking to enjoy a satisfying, low-calorie treat. 

4. Chayote Squash 

Chayote squash, also known as vegetable pear or mirliton, is a green, wrinkled fruit commonly used in culinary dishes. It has a mild, crisp texture and is versatile in both savoury and sweet chayote squash recipes. Chayote is known for its high fibre content and can be cooked or eaten raw, making it a nutritious addition to a balanced diet. Its subtle flavor allows it to absorb the tastes of the dishes it’s incorporated into, making it a popular choice in various cuisines around the world. 

5. Chayote Desserts

Chayote desserts offer a unique and healthy twist to sweet treats. From chayote pies to puddings, these creations incorporate the mild, crisp texture of chayote into delightful, low-calorie desserts. With their versatility, chayote desserts are gaining popularity among those looking for a nutritious alternative to traditional sweets. 

Experiment with these chayote recipes to make the most of chayote’s unique flavour and versatility. Whether you’re looking for a healthy side dish, a filling main course, or a sweet treat, chayote can be a delightful addition to your culinary repertoire. 

Also Read: Pudina (Mint): Uses, Benefits, Side Effects & More!

Conclusion 

Chayote is a nutrient-rich vegetable with potential health benefits, including heart support, blood sugar regulation, and antioxidant protection. It can be a healthy addition to your diet when consumed in moderation. However, consult a doctor before using it for medicinal purposes. 

Frequently Asked Questions (FAQs)

What part of the chayote plant is edible?

The fruit, including the seeds, rind, peel, and flesh are edible. You can also eat its tendrils, flowers, and roots. There are several health benefits of eating chayote raw or cooked.   

Is chayote good for diabetes?

Yes, chayote benefits people with diabetes by lowering their blood sugar levels.  Additionally, the nutritional benefits of chayote help in slowing the absorption of carbohydrates which further reduces food intake, weight and thereby, sugar intake. However, you should consult a doctor before using chayote for weight loss and diabetes.   

What are chayote juice benefits? 

There are many health benefits of chayote juice. The extract from chayote fruit may help in promoting healthy digestion, regulating blood pressure, and slowing down the ageing process. Many people prefer having chayote juice for weight loss after working out. However, you should consult a doctor before using chayote for skin, high blood pressure, and digestive issues.   

Is chayote good for the kidney?

Chayote may reduce the formation of kidney stones. However, you should consult a doctor before self-medicating chayote for kidney stones.  

What are the health benefits of chayote?

Chayote is widely used in the pharmaceutical and cosmetic industries. It promotes heart health, prevents cancer, lowers blood pressure, regulates blood sugar, prevents fat accumulation in the liver, fights inflammation, and slows the ageing process. However, you should consult a doctor before utilising chayote benefits for high blood pressure and overall health.  

What is chayote?

Chayote is a green, wrinkled vegetable, scientifically known as Sechium edule. It belongs to the Cucurbitaceae family and is often used in various culinary dishes. It’s also known as mirliton squash, chocho, or guisquil in different regions. 

How to eat chayote? 

To eat chayote, you can peel and slice it for use in salads, stir-fries, or as a raw snack. It can also be cooked by boiling, steaming, or roasting. Chayote is versatile and pairs well with various flavors and cuisines. 

Is chayote good for babies?

Chayote benefits for baby become evident as it can be a nutritious addition to a baby’s diet, offering essential vitamins and dietary fiber. However, it’s crucial to consult with a pediatrician before introducing new foods to ensure they are suitable for the baby’s age and specific dietary needs. 

Is chayote good for uric acid?

Chayote is considered a relatively safe choice for individuals with high uric acid levels, as it is low in purines that can contribute to uric acid production. However, individual responses may vary, so it’s advisable to monitor how your body reacts to chayote and consult a healthcare provider or dietitian for personalized dietary recommendations. 

Is chayote high in potassium? 

Chayote is relatively low in potassium compared to many other fruits and vegetables, making it a suitable choice for individuals who need to restrict their potassium intake, such as those with kidney issues. However, portion control and overall dietary considerations are still important for individuals with specific potassium restrictions. 

References

  1. Pu Y-T, Luo Q, Wen L-H, Li Y-R, Meng P-H, Wang X-J, et al. Origin, evolution, breeding, and omics of chayote, an important Cucurbitaceae vegetable crop [Internet]. Front Plant Sci [Internet]. 2021 [cited 2025 Jun 4];12:739091. Available from: https://www.frontiersin.org/articles/10.3389/fpls.2021.739091/full 
  2. Vieira EF, Pinho O, Ferreira IMPLVO, Delerue-Matos C. Chayote (Sechium edule): A review of nutritional composition, bioactivities and potential applications. Food Chem. 2019 Mar 1;275:557-568. doi: 10.1016/j.foodchem.2018.09.146. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0308814618317230?via%3Dihub    
  3. Gavia-García G, Hernández-Álvarez D, Arista-Ugalde TL, Aguiñiga-Sánchez I, Santiago-Osorio E, Mendoza-Núñez VM, Rosado-Pérez J. The Supplementation of Sechium edule var. nigrum spinosum (Chayote) Promotes Nrf2-Mediated Antioxidant Protection in Older Adults with Metabolic Syndrome. Nutrients. 2023 Sep 22;15(19):4106. doi: 10.3390/nu15194106. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10574595/ 
  4. U.S. Department of Agriculture, Agricultural Research Service. FoodData Central. Chayote, fruit, raw [Internet]. Beltsville (MD): USDA; 2019 Apr 1 [cited 2025 Jun 4]. Available from: https://fdc.nal.usda.gov/food-details/170402/nutrients  
  5. Salazar-Aguilar S, Ruiz-Posadas LDM, Cadena-Iñiguez J, Soto-Hernández M, Santiago-Osorio E, Aguiñiga-Sánchez I, et al. Sechium edule (Jacq.) Swartz, a new cultivar with antiproliferative potential in a human cervical cancer HeLa cell line [Internet]. Nutrients. U.S. National Library of Medicine; [cited 2022 Dec 16]. Available from: https://pubmed.ncbi.nlm.nih.gov/28757593/ 
  6. Ordoñez AAL, Gomez JD, Cudmani NM, Vattuone MA, Isla MI. Antimicrobial activity of nine extracts of Sechium edule (Jacq.) Swartz. Microb Ecol Health Dis. 2003;15:33–39. Available from: https://core.ac.uk/download/pdf/323211428.pdf  
  7. Yang MY, Chan KC, Lee YJ, Chang XZ, Wu CH, Wang CJ. Sechium edule Shoot Extracts and Active Components Improve Obesity and a Fatty Liver That Involved Reducing Hepatic Lipogenesis and Adipogenesis in High-Fat-Diet-Fed Rats. J Agric Food Chem. 2015 May 13;63(18):4587-96. doi: 10.1021/acs.jafc.5b00346. Available from: https://pubmed.ncbi.nlm.nih.gov/25912298/  
  8. Ibarra-Alvarado C, Rojas A, Mendoza S, Bah M, Gutiérrez DM, Hernández-Sandoval L, et al. Vasoactive and antioxidant activities of plants used in Mexican traditional medicine for the treatment of cardiovascular diseases [Internet]. Pharm Biol [Internet]. [cited 2022 Dec 16];48(5):468–75. Available from: https://pubmed.ncbi.nlm.nih.gov/20645769/  
  9. McRae MP. Dietary fiber is beneficial for the prevention of cardiovascular disease: an umbrella review of meta-analyses [Internet]. J Chiropr Med. 2017 Dec;16(4):289–99 [cited 2025 June 04]. Available from: https://pubmed.ncbi.nlm.nih.gov/29276461/ 
  10. Tiwari AK. Revisiting “Vegetables” to combat modern epidemic of imbalanced glucose homeostasis. Pharmacogn Mag. 2014;10(Suppl 2):S207–S213. Available from: https://phcog.com/article/view/2014/10/38s/s207-s213     
  11. Greenberg JA, Bell SJ, Guan Y, Yu YH. Folic Acid supplementation and pregnancy: more than just neural tube defect prevention. Rev Obstet Gynecol. 2011 Summer;4(2):52-9. Available from: https://pubmed.ncbi.nlm.nih.gov/22102928/ 
  12. Fauziah NA, Hidajati K, Soejoenoes A. The effect of chayote extract (Sechium edule) on blood pressure in pregnant women with hypertension. Indones J Med. 2019;4(3):266–77. doi:10.26911/theijmed.2019.04.03.10. Available from: https://www.cabidigitallibrary.org/doi/pdf/10.5555/20203262858  
  13. Aguiñiga-Sánchez I, Soto-Hernández M, Cadena-Iñiguez J, Ruíz-Posadas Ldel M, Cadena-Zamudio JD, González-Ugarte AK, Steider BW, Santiago-Osorio E. Fruit extract from a Sechium edule hybrid induce apoptosis in leukaemic cell lines but not in normal cells. Nutr Cancer. 2015;67(2):250-7. doi: 10.1080/01635581.2015.989370. Available from: https://pubmed.ncbi.nlm.nih.gov/25611564/ 
  14. Elavarasan, N., Kokila, K., Inbasekar, G., and Sujatha, V. (2016). Evaluation of photocatalytic activity, antibacterial and cytotoxic effects of green synthesized ZnO nanoparticles by Sechium edule leaf extract. Res. Chem. Intermediat. 43, 1–16. doi: 10.1007/s11164-016-2830-2. Available from: https://link.springer.com/article/10.1007/s11164-016-2830-2 
  15. Sergiev PV, Dontsova OA, Berezkin GV. Theories of aging: an ever-evolving field.   Acta Naturae. 2015 Jan-Mar;7(1):9-18. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4410392/  
  16. Metral E, Rachidi W, Damour O, Demarne F, Bechetoille N. Long-term Genoprotection Effect of Sechium edule Fruit Extract Against UVA Irradiation in Keratinocytes. Photochem Photobiol. 2018 Mar;94(2):343-350. doi: 10.1111/php.12854. Available from: https://pubmed.ncbi.nlm.nih.gov/29110298/  
  17. Fauziah, N. A., Hidajati, K., and Soejoenoes, A. (2019). The effect of chayote extract (Sechium edule) on blood pressure in pregnant women with hypertension. Indonesian J. Med. 4, 266–277. doi: 10.26911/theijmed.2019.04.03.10. Available from: https://onlinelibrary.wiley.com/doi/10.1155/2014/594326  
  18. Del Ángel Coronel OA, León-García E, Vela-Gutiérrez G, De la Cruz Medina J, García-Varela R, García HS. Chayote (Sechium edule (Jacq.) Swartz). In: Yahia EM, editor. Fruit and Vegetable Phytochemicals: Chemistry and Human Health. 2nd ed. Hoboken (NJ): Wiley-Blackwell; 2017. p. 1025–38. doi:10.1002/9781119158042.ch47. Available from: https://www.researchgate.net/publication/320428959_Chayote_Sechium_edule_Jacq_Swartz_Chemistry_and_Human_Health_2nd_Edition  
  19. Pu YT, Luo Q, Wen LH, Li YR, Meng PH, Wang XJ, Tan GF. Origin, evolution, breeding, and omics of chayote, an important Cucurbitaceae vegetable crop. Front Plant Sci. 2021 Sep 24;12:739091. doi: 10.3389/fpls.2021.739091. PMID: 34630492; PMCID: PMC8497889. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497889/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof. 

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Kodo Millets: Uses, Benefits, Side Effects, And More

Introduction

Kodo millets, botanically known as Paspalum scrobiculatum, is a traditional grain belonging to the Poaceae family. It is often referred to in English as rice grass, ditch millet, or cow grass. Regionally, it is known as araka in Telugu and kodra in Marathi. The grains of kodo millet vary in colour from light red to dark grey and are cultivated annually.

The history of kodo millet cultivation in India dates back approximately 3,000 years. In addition to India, it is also grown in countries such as Russia, China, various parts of Africa, and Japan. Within India, it is primarily cultivated in the states of Madhya Pradesh, Tamil Nadu, Karnataka, Gujarat, and Chhattisgarh. 

Among all the millets available, Kodo millets are well known for its resilience to drought and its ability to produce a reasonable yield within a short period. As a result, it holds significant economic importance, particularly in regions where agriculture is challenged by water scarcity. India leads the world in the production of kodo millet

Kodo millets are cultivated in the kharif season (monsoon season) and are available in different varieties, namely Indira kodo, Jawahar kodo, and TNAU. Kodo millets are processed into value-added foods and drinks. While kodo millet is appreciated for its nutritional content and is a staple in many traditional diets, it is important to note that any health-related benefits should be interpreted with caution. The grain may form part of a balanced diet, but it is not intended to diagnose, treat, cure, or prevent any medical condition. Individuals with specific health concerns should consult a qualified healthcare professional before making dietary changes1,2.

Did you know?

Nutritional Value of Kodo Millets

Kodo millet is a nutritious grain containing carbohydrates, protein, and dietary fibre. It also provides B-vitamins such as niacin and riboflavin, along with minerals like calcium, iron, and phosphorus. Additionally, it contains natural phytochemicals, including antioxidants and phenolic compounds such as vanillic acid, gallic acid, tannins, and ferulic acid.

Here are the nutritional components of kodo millet per 100 grams2:

In my own viewpoint, this humble grain is not only delicious but also has some surprising health benefits. Kodo millet is believed to have properties that might help in asthma. Not only that it might be beneficial for people suffering from migraine.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Kodo Millets

Scientific studies have explored various characteristics of kodo millet. Some of the observed and researched properties are outlined below:

Let me tell you that these tiny grains might be heroes for your gallbladder! Kodo millets, thanks to their high fibre content, have the potential to avoid the formation of gallstones12.

Dr. Rajeev Singh, BAMS

Potential Uses of Kodo Millets for Overall Health

Some of the potential benefits of kodo millets are described as follows:  

1. Potential Uses of Kodo Millets on Lipid Profile

Hyperlipidemia is the elevation in lipid components like triglycerides, total cholesterol, and reduced levels of high-density lipoprotein. An animal study4 investigated the potential effects of kodo millet on lipid levels in rats. The findings suggested that kodo millet consumption was associated with reduced levels of total cholesterol, triglycerides, and low-density lipoprotein (LDL), while increasing HDL levels. However, we need more clinical studies to support these claims in humans.  

2. Potential Uses of Kodo Millets for Bacterial Infections

Literature shows that the consumption of kodo millets may have the potential to manage bacterial infections. A review5 conducted noted that kodo millets could inhibit the growth of bacteria like S.aureus, Bacillus cereus, Leuconostoc mesenteroides and Enterococcus faecalis which are organisms associated with infections such as urinary tract infections and diarrhoea. However, we need more studies to support these claims. 

3. Potential Uses of Kodo Millets for Type-2 Diabetes

Type-2 diabetes is a metabolic disorder characterised by an increase in blood glucose due to decreased production or resistance to a hormone called insulin which regulates blood glucose. A review6 conducted suggested that kodo millets may have the potential to decrease blood glucose levels. This effect is attributed to polyphenols, which inhibit enzymes that break down carbohydrates into simpler sugars and increase blood glucose. Additionally, kodo millets have a low glycaemic index. Certain phenolic compounds found in kodo millets have been studied for their potential to inhibit enzymes such as aldose reductase. This enzyme is involved in the conversion of glucose to sorbitol, an accumulation of which has been linked to diabetic complications, including cataract formation. However, there are not enough studies to support these claims and therefore should only be used under the supervision of a medical professional.

4. Potential Uses of Kodo Millets in Cancer

Literature studies have supported the use of kodo millets may possess properties to reduce the risk of cancers. A review study2 indicated that kodo millets may potentially reduce cancer initiation and progression. This anti-cancer effect is attributed to the presence of phenolic acids, phytic acids, and tannins in the grain. However, we need more scientific evidence to support these claims. 

5. Potential Uses of Kodo Millets in Malnutrition

Malnutrition is defined as the deficiency, excess, or imbalance in the intake of energy or nutrients. The term malnutrition addresses 3 broad groups of conditions as follows:

Kodo millets are highly nutritious due to the presence of carbohydrates, proteins, dietary fibres, vitamins (like niacin and riboflavin) and minerals (like calcium, iron, and phosphors). Kodo millets are also rich in antioxidants and phenolic compounds like vanillic acid, gallic acid, tannins, and ferulic acid. A review study6 suggested that kodo millets may help manage micronutrient-related malnutrition. Thus, the consumption of Kodo millet may positively impact malnutrition. Though scientific evidence to support these claims is limited, we need more studies to ascertain these claims with better results.

6. Other Potential Uses of Kodo Millets

Though there are studies that show the benefits of kodo millets in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kodo millets on human health.  

In my knowledge, kodo millets with their abundance of nutrients, have been found to have great benefits. They’re not just for filling your plate; they might actually help with inflammation, haemorrhages (excessive bleeding), and general weakness10.

Dr. Smita Barode, B.A.M.S, M.S.

How to Use Kodo Millets?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

I have read in a research paper that the dried ethanol extract of kodo millet husk, when consumed, may have interesting effects on both animals and humans. It has been observed that this extract might cause a calming effect, leading to tranquillity, in various animal species. Additionally, when a human volunteer took the extract, they also experienced possible drowsiness11.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

Side Effects of Kodo Millets

A few side effects related to the consumption of kodo millets include:  

However, if you experience any adverse reactions to Kodo millet, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Precautions to Take with Kodo Millets

Eating kodo millet is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions: 

Interactions with Other Drugs

Therefore, you must always seek the advice of your Ayurvedic physician before incorporating kodo millet into your routine, especially if you are on medication. They can provide personalised advice based on your medical history and current treatment plan, helping to avoid any potential interactions.

Conclusion 

Kodo millet stands out as a grain with a rich history, impressive nutritional profile, and potential health benefits. Its drought resistance and economic value make it a vital crop, particularly in water-scarce regions. While research continues to explore its medicinal properties, incorporating kodo millet into a balanced diet may support overall health, when used under proper guidance.

Frequently Asked Questions (FAQs)

What is the name of Kodo millet in Marathi?

Kodo millet is called “Kodra” in Marathi. 

What are the different varieties of Kodo millets available in the market?

The different kodo millet varieties available in the market include Indira kodo, Jawahar kodo, and TNAU.

Should kodo millets be soaked before use?

Yes, kodo millets contain certain naturally occurring compounds, known as anti-nutrients, such as phytic acid and polyphenols. These substances reduce the availability of nutritional components and processing methods like soaking will help decrease the level of these anti-nutrients.

Can we use Kodo millet for weight loss?  

Yes, as kodo millet is low in fat content and high in protein and fibre, it increases satiety and reduces overeating, and may help in weight loss.

What are the side effects of Kodo millets?

Contaminated or improperly stored kodo millet may cause kodo poisoning, potentially leading to elevated liver enzymes, nausea, vomiting, and, in severe cases, unconsciousness. The grain
also contains goitrogens, which may interfere with thyroid function and contribute to goitre if consumed excessively without adequate iodine intake.

References

  1. Bunkar et al. Nutritional, Functional Role of Kodo Millet and its Processing: A Review, International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 10 Number 01 (2021). Available at:  https://doi.org/10.20546/ijcmas.2021.1001.229 
  2. NUTRI CEREALS- IYoM 2023. Available at: https://nutricereals.dac.gov.in/
  3. Naturally Yours , Kodo Millet – nutrition, benefits and recipes, Naturally Yours. Available at: https://naturallyyours.in/blogs/blog/kodo-millet-nutrion-benefits-and-recipes
  4. Satish Narra, Bandenawaz Ramadurg, Saraswathi CD. Antihyperlipidemic Activity of Paspalum scrobiculatum L. Grains Extract in Albino Rats. Research J. Pharmacology and Pharmacodynamics. 2013; 5(6): 362-370. Available at: https://rjppd.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacology%20and%20Pharmacodynamics;PID=2013-5-6-20 
  5. Sharma S, Sharma N, Handa S, Pathania S. Evaluation of health potential of nutritionally enriched Kodo millet (Eleusine coracana) grown in Himachal Pradesh, India. Food Chem. 2017 Jan 1;214:162-168. doi: 10.1016/j.foodchem.2016.07.086. Epub 2016 Jul 12. PMID: 27507461. Available at: https://pubmed.ncbi.nlm.nih.gov/27507461/ 
  6. Wang, Han et al. “Effect of Different Processing Methods on the Millet Polyphenols and Their Anti-diabetic Potential.” Frontiers in nutrition vol. 9 780499. 11 Feb. 2022, doi:10.3389/fnut.2022.780499. Available at: https://www.researchgate.net/publication/358534642_Effect_of_Different_Processing_Methods_on_the_Millet_Polyphenols_and_Their_Anti-diabetic_Potential 
  7. Vinoth, A, and R Ravindhran. “Biofortification in Millets: A Sustainable Approach for Nutritional Security.” Frontiers in plant science vol. 8 29. 23 Jan. 2017, doi:10.3389/fpls.2017.00029. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253353/ 
  8. Antony, Mary et al. “Potential risk of acute hepatotoxicity of kodo poisoning due to exposure to cyclopiazonic acid.” Journal of ethnopharmacology vol. 87,2-3 (2003): 211-4. doi:10.1016/s0378-8741(03)00146-6. Available at: https://pubmed.ncbi.nlm.nih.gov/12860310/ 
  9. Sonali et al. “Millets – Miracle grain”. Rashtriya Krishi | Vol. 15 (1)| Jun., 2020. Available at: http://researchjournal.co.in/online/RKE/RKE-15(1)/15_57-60.pdf 
  10. Bhatia G, Joshi S, Barve A, Nema RK, Joshi A, Gehlot S. Phytochemical Studies of the Grains of Paspalum scrobiculatum. Int J Pharm Clin Res. 2010;2(2):66-67.Available at: https://www.researchgate.net/publication/312041797_Phytochemical_Studies_of_the_Grains_of_Paspalum_scrobiculatum
  11. Bhide NK. Pharmacological study and fractionation of Paspalum scrobiculatum extract. British Journal of Pharmacology and Chemotherapy. 1962 Feb;18(1):7-18.Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC1482178/pdf/bripharmchem00062-0013.pdf
  12. Deshpande S S, Mohapatra D, Tripathi M K, Sadvatha R H. Kodo millet-nutritional value and utilization in Indian foods [Internet]. Journal of Grain Processing and Storage. 2015 [cited 2025 Oct 9];2(2):16-23. Available from:https://www.academia.edu/72641412/Kodo_millet_nutritional_value_and_utilization_in_Indian_foods

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof. 

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Red Rice: Uses, Benefits, Side Effects & More

Introduction

According to Balinese mythology, a divine bird was sent to Earth carrying four seeds coloured red, white, black, and yellow. During its journey, the bird consumed the yellow seed, leaving only the red, white, and black ones. These are believed to represent the various types of rice grains known today. 

Among them, red rice stands out for its distinctive colour and traditional significance. Commonly referred to by different names such as Oryza longistaminata, Matta rice, Palakkadan Matta rice, and Rakthashali in Ayurveda, red rice owes its rich hue to the presence of anthocyanin, a natural antioxidant pigment. 

Red rice can appear in several forms, which include wild, weedy, or cultivated and may be partially or fully covered with husk. It has been traditionally cultivated in regions such as Sri Lanka, China, the United States, Korea, and India. Within India, red rice is grown in various states, including Karnataka, Tamil Nadu, Kerala, Odisha, and Madhya Pradesh. Notable varieties include Patni from Maharashtra, Matali and Jatu from Kullu, and Matta from Kerala1.  

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Nutritional Value of Red Rice

Red rice is a nutritional powerhouse. It contains proteins, carbohydrates, mono-unsaturated fatty acids, vitamins, and minerals like zinc and iron. Additionally, red rice is a source of polyphenols, including vanillic acid and ferulic acid, as well as antioxidants like anthocyanins, proanthocyanidins, and flavonoids, which are responsible for its characteristic colour. The nutritional components of red rice per 100 grams are given below2:   

Properties of Red Rice

Scientific studies have examined various aspects of red rice, and its consumption has been associated with several beneficial nutritional properties. Some of these observed characteristics are outlined below, based on available research and traditional dietary usage. 

Potential Uses of Red Rice for Overall Health

Some of the potential benefits of red rice are described as below:  

1. Potential Uses of Red Rice in Inflammation  

Inflammation is the body’s natural defence mechanism in response to infection, stress, or tissue injury. It can be acute, such as in the case of fever, or chronic, as seen in long-term conditions like arthritis. A systematic review12 has reported that red rice may exhibit anti-inflammatory and antioxidant properties in certain experimental settings. Antioxidants are known to help protect cells from oxidative stress and may assist in reducing inflammatory responses. These potential effects are attributed to the presence of naturally occurring compounds in red rice, such as gamma-oryzanol, flavonoids, and phenolic compounds3.   

While such findings are of interest, it is important to note that more robust scientific studies are needed to confirm these observations. At present, there is insufficient clinical evidence to support any definitive health claims regarding the management or treatment of inflammatory conditions through the consumption of red rice.  

2. Potential Uses of Red Rice in Breast Cancer

Breast cancer is one of the most commonly diagnosed cancers affecting women worldwide. Some preliminary research13 has investigated the potential effects of red rice on breast cancer cells in laboratory settings. Findings from these studies suggest that certain compounds present in red rice, such as polyphenols, particularly proanthocyanidins may influence cellular processes related to cancer progression. For example, red rice extracts have been observed to inhibit the activity of interleukin-6 (IL-6), a protein associated with cell growth and may also play a role in reducing cell migration in vitro4.  

However, it is important to emphasise that these studies are experimental in nature, and the results have not been confirmed through large-scale clinical trials. At this stage, there is no conclusive evidence to support any preventive or therapeutic claims related to breast cancer, and further research is required. Individuals should consult with qualified healthcare professionals for medical advice or treatment..  

3. Potential Uses of Red Rice for Alopecia

Alopecia is the loss of hair or baldness. Red rice is naturally rich in protein and other nutrients, which are important for general health, including the maintenance of hair. Some experimental research5 has explored the potential impact of red rice on hair health. In one such study, red rice extract was found to inhibit the activity of the enzyme 5-alpha reductase, which is associated with hair loss in certain conditions. These findings suggest a possible link between compounds found in red rice and reduced hair shedding in laboratory models. However, these results are preliminary and have not been confirmed through extensive human studies. At present, there is insufficient scientific evidence to support the use of red rice in managing alopecia, and individuals experiencing hair loss are advised to seek guidance from a qualified medical professional.  

4. Potential Uses of Red Rice in Type-2-Diabetes

Type 2 diabetes is characterised by elevated blood glucose levels either due to a decreased insulin level or resistance of the body to insulin (a hormone that regulates blood glucose levels). A study6 in 2020 investigated the potential effects of red rice in a diabetic mouse model. The findings suggested that red rice consumption may be associated with improved insulin sensitivity and a lower glycaemic response in that experimental context. These observations were attributed to the naturally low glycaemic index of red rice and the presence of certain bioactive compounds. While these results are scientifically noteworthy, 

 it is important to recognise that the study was conducted on animals, and further well-designed clinical trials in humans are necessary to confirm these outcomes. At present, there is not enough evidence to support any definitive health claims regarding the management of Type 2 diabetes through red rice consumption. Individuals with diabetes should consult a qualified healthcare provider for appropriate dietary and medical guidance.  

5. Potential Uses of Red Rice on Dyslipidemia

Dyslipidemia is characterised by elevated cholesterol, including increased low-density lipoprotein, often referred to as ‘bad’ cholesterol, and decreased high-density lipoprotein (HDL), known as ‘good’ cholesterol. A review of existing research7 has noted that red yeast rice, which is a fermented form of red rice, may help reduce cholesterol levels by inhibiting its synthesis in the body. 

Additionally, the presence of naturally occurring phytosterols and monounsaturated fatty acids in red rice has been associated with potential benefits in managing lipid profiles. These findings suggest that red rice might have a positive effect on dyslipidemia8. However, further rigorous studies are required to establish these claims with greater scientific certainty.  

6. Potential Uses of Red Rice on Digestion

Literature indicates that diets rich in dietary fibre are generally associated with a reduced intake of fats and may contribute to improved digestive health. Traditional Chinese medicine has historically used red rice as a natural help for digestion8.  As a good source of dietary fibre, red rice may support regular bowel movements and provide relief from constipation. Furthermore, red rice is naturally low in fat while being relatively high in protein and fibre, which can promote feelings of fullness, potentially reducing overeating and supporting metabolic health. These characteristics suggest that consuming red rice could be beneficial for digestion, relief from constipation, and maintaining a healthy weight1. However, further scientific studies are needed to confirm these effects.  

7. Other Potential Uses of Red Rice

Though there are studies that show the benefits of red rice in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of red rice on human health.   

As red rice is a good source of many nutrients, including phytochemicals, which are believed to possess properties that may support skin health and potentially contribute to anti-ageing effects15.

Dr. Rajeev Singh, BAMS

How to Use Red Rice?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.    

Also Read: 14 Health Benefits of Amaranth Leaves That You Must Know

Side Effects of Red Rice

Few side effects related to the consumption of red rice include:  

However, if you experience any adverse reactions to red rice, it is advised to discontinue its use immediately and consult a doctor or the Ayurvedic physician who prescribed it. They can provide appropriate guidance based on your symptoms.” 

Certain studies14 have explored the potential of red yeast rice in supporting bone health. Preliminary findings from these studies suggest that red yeast rice may have a role in promoting bone formation.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Precautions to Take with Red Rice

Eating red rice is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions:  

Also Read: Plums (Aloo Bukhara): Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

Therefore, you must always seek the advice of your Ayurvedic physician about the possible interaction of red rice with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking.  

Also Read: Clove (Laung): Uses, Benefits, Side Effects and More!

Conclusion

Red rice is a nutrient-rich grain with potential health benefits supported by both traditional knowledge and preliminary scientific studies. While promising, its therapeutic claims require more clinical evidence for confirmation. As with any supplement, it should be consumed with caution and professional guidance. 

Frequently Asked Questions (FAQs)

Is red rice better than white rice?

Yes. In comparison with white rice, red rice is rich in zinc and iron which may offer several health benefits. 

What are the different red rice varieties?

Some famous red rice varieties include Patni of Maharashtra, Matali and Jatu of Kullu, and Matta of Kerala. 

Can red rice help in weight loss?  

Yes. Red rice is low in fat and high in protein and fibres, which increases satiety and reduces overeating, which may help in weight loss. 

What are the side effects of red rice consumption?

If red rice is fermented consumed improperly, it may be associated with a risk of liver injury. Excessive intake of red rice can lead to digestive discomfort, including indigestion, bloating, and stomach pain, primarily due to its high fibre and protein content. While red rice consumption is generally not known to cause allergic reactions, in some cases, it may be linked to symptoms such as itching, rashes, or swelling. The precise causes and mechanisms underlying these reactions are not yet fully understood. 

References

  1. Ahuja U, Ahuja S, Chaudhary N, Thakrar R. Red Rices – Past, Present, and Future. Asian Agri-History [Internet]. 2007 Oct 1 [cited 2025 May 27];11(4). Available from: https://www.researchgate.net/publication/237785312_Red_Rices_-_Past_Present_and_Future  
  2. US Department of Agriculture. FoodData Central [Internet]. Usda.gov. 2019 [cited 2025 May 27]. Available from: https://fdc.nal.usda.gov/food-details/2710838/nutrients  
  3. Agustin AT, Safitri A, Fatchiyah F. Java Red Rice (Oryza sativa L.) Nutritional Value and Anthocyanin Profiles and Its Potential Role as Antioxidant and Anti-Diabetic. Indonesian Journal of Chemistry [Internet]. 2021 Aug 3 [cited 2025 May 27];21(4):968. Available from: https://www.researchgate.net/publication/353975212_Java_Red_Rice_Oryza_sativa_L_Nutritional_Value_and_Anthocyanin_Profiles_and_Its_Potential_Role_as_Antioxidant_and_Anti-Diabetic  
  4. Pintha, Komsak et al. “Proanthocyanidin in red rice inhibits MDA-MB-231 breast cancer cell invasion via the expression control of invasive proteins.” Biological & pharmaceutical bulletin vol. 38,4 (2015): 571-81. doi:10.1248/bpb.b14-00719. Available at: https://pubmed.ncbi.nlm.nih.gov/25735761/  
  5. Jeng et al. (2012). Agronomic, molecular and antioxidative characterization of red- and purple-pericarp rice (Oryza sativa L.) mutants in Taiwan. Journal of Cereal Science. 56. 425–431. 10.1016/j.jcs.2012.05.015. Available at: https://www.mdpi.com/2079-9284/9/6/111  
  6. Yagi, Takakazu et al. “Red rice kojiextract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in skeletal muscle in two diabetic mouse models.” Food & nutrition research vol. 64 10.29219/fnr.v64.4226. 8 Oct. 2020, doi:10.29219/fnr.v64.4226. Available at: https://pubmed.ncbi.nlm.nih.gov/33240034/  
  7. Shamim, Shariq et al. “Red yeast rice for dysipidemia.” Missouri medicine vol. 110,4 (2013): 349-54. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179893/  
  8. Musselman ME, Pettit RS, Derenski KL. A Review and Update of Red Yeast Rice. Journal of Evidence-Based Complementary & Alternative Medicine [Internet]. 2011 Dec 4 [cited 2025 May 27];17(1):33–9. Available from: https://journals.sagepub.com/doi/full/10.1177/2156587211429703  
  9. Mazzanti, Gabriela et al. “Adverse reactions to dietary supplements containing red yeast rice: assessment of cases from the Italian surveillance system.” British journal of clinical pharmacology vol. 83,4 (2017): 894-908. doi:10.1111/bcp.13171. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346868/  
  10. Jeon, You Hoon et al. “Identification of major rice allergen and their clinical significance in children.” Korean journal of pediatrics vol. 54,10 (2011): 414-21. doi:10.3345/kjp.2011.54.10.414. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250595/  
  11. Twarużek, Magdalena et al. “Dietary Supplements Based on Red Yeast Rice-A Source of Citrinin?.” Toxins vol. 13,7 497. 17 Jul. 2021, doi:10.3390/toxins13070497. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310238/
  12. Limtrakul P, Yodkeeree S, Pitchakarn P, Punfa W. Anti‑inflammatory effects of proanthocyanidin‑rich red rice extract via suppression of MAPK, AP‑1 and NF‑κB pathways in Raw 264.7 macrophages. Nutr Res Pract. 2016 Jun;10(3):251–8. doi: 10.4162/nrp.2016.10.3.251. Epub 2016 Apr 1. PMID: 27247720; PMCID: PMC4880723. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880723/ 
  13. Chen Z, Theppawong A, Sangsawad P, Fang J, Ye H, Deng S, Yang M, Gao J, Kraithong S. Bioactive compounds in colored rice: exploring natural agents for cancer prevention in vitro and rodent model studies. J Funct Foods. 2025 May;129:106875. doi: 10.1016/j.jff.2025.106875. Available from: https://www.sciencedirect.com/science/article/pii/S1756464625002178
  14. Wu B, Huang JF, He BJ, Huang CW, Lu JH. Promotion of bone formation by red yeast rice in experimental animals: a systematic review and meta‐analysis. Biomed Res Int. 2020 Aug 8;2020:7231827. doi:10.1155/2020/7231827. PMID:32832555; PMCID:PMC7429765. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429765/
  15. Baptista E, Liberal Â, Cardoso RVC, Fernandes Â, Dias MI, Pires TCSP, Calhelha RC, García PA, Ferreira ICFR, Barreira JCM. Chemical and bioactive properties of red rice with potential pharmaceutical use. Molecules. 2024 May 11;29(10):2265. doi: 10.3390/molecules29102265. PMID: 38792127; PMCID: PMC11123668. Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC11123668/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof. 

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Halim Seeds: Uses, Benefits, Side Effects and More By Dr. Rajeev Singh

Introduction

Halim seeds, also known as garden cress seeds, are tiny reddish-brown seeds packed with nutrition and health benefits. Used for centuries in traditional medicine and cooking, they have been valued for their medicinal properties and rich nutrient profile.

These seeds come from Lepidium sativum, an edible herb belonging to the Brassicaceae family. Originally native to Egypt, the plant is now cultivated worldwide, including in India, where it is primarily grown in Madhya Pradesh, Gujarat, Rajasthan, and Uttar Pradesh. The plant produces light pink or white flowers and tiny seed pods, which are harvested for their seeds.


Halim seeds are also known by different names across regions, such as Holan, Chandrasura, Aliv seeds, and garden cress. With their impressive nutritional value, they have gained popularity as a superfood. Let’s explore the numerous health benefits these tiny seeds have to offer1.

Nutritional Value of Halim Seeds

Halim seeds are packed with the goodness of carbohydrates, proteins, fibers and minerals like calcium, phosphorus, zinc, etc. and phytochemicals like flavonoids, phenols, lectins, tannins, glycosides, etc. The nutritional components and bioactive components of Halim seeds are mentioned below: 

Properties of Halim Seeds

Scientifically proven properties of Halim seeds include: 

Based on my experience, I have found that the extract from halim seeds shows promising potential as an antifungal agent. It has been observed to effectively inhibit the growth of various fungal species. Halim seeds may possess strong antifungal properties, which could be beneficial in the management of fungal infections.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Halim Seeds for Overall Health

Some of the potential benefits of Halim seeds are described below:  

1. Potential Uses of Halim Seeds in Type 2 Diabetes 

Type 2 diabetes is a metabolic disorder characterised by hyperglycemia (an increase in blood glucose levels) with reduced or total loss of insulin (a hormone that regulates blood glucose in the body) function.

Qusti et al. conducted a study4 in 2016 to assess the effects of Halim seeds in diabetic rats. The study showed that Halim seeds showed a significant decrease in blood glucose levels. This effect was attributed to the inhibition of molecules which inhibit the insulin pathway. This indicates that Halim seeds may help in managing diabetes. However, we need more studies to support these claims in humans.

2. Potential Uses of Halim Seeds in Bone Health 

Strong bones reduce the risk of fractures and protect vital organs like the brain and heart from damage. To build strong bones and promote bone healing in fractures, calcium and Vitamin D play an important role.

Dixit et al. conducted a study1 on rats in 2020, stating that Halim seeds may positively impact bone health and help promote bone healing in case of fractures due to the presence of calcium and phosphorus in high amounts. This indicates that Halim seed consumption may have a positive impact on bone fractures, provided more human studies are done to support these claims.

3. Potential Uses of Halim Seeds on Obesity 

Obesity is defined as an excessive or abnormal accumulation of fat in the body. A Body Mass Index (BMI)>25 kg/m2 is defined as overweight, and >30 kg/m2 is considered obese. Reducing body weight may help in managing obesity.

Dixit et al. conducted a study4 in 2020 to assess the effect of Halim seeds on obese rats; the study findings supported the use of Halim seeds for weight loss. This indicates that Halim seed consumption may help manage obesity by reducing weight. However, we need more studies to support these claims in humans.

4. Potential Uses of Halim Seeds in Breast Cancer 

Breast cancer is one of the most common cancers affecting women worldwide. Literature reviews support the use of dietary agents and a reduced risk of breast cancer.

Mahassni et al. conducted a literature review5 in 2013, stating Halim seeds contain phytochemicals like organo-sulfur compounds and phytosterols, which have antioxidant and anti-inflammatory effects and may inhibit cell multiplication, arrest the cancer cell cycle and cause apoptosis (cell death of cancer cells). This indicates that Halim seeds may exert an anti-cancer effect on breast cancer. However, there is limited evidence, and we need more studies to support these claims in humans.

5. Potential Uses of Halim Seeds on Hyperlipidemia 

Hyperlipidemia or hyperlipoproteinemia is defined as an increase in total cholesterol, a reduction in low-density lipoprotein or bad cholesterol and an increase in high-density lipoprotein or good cholesterol.

Yousef et al. conducted a study6 in 2014 to assess the effects of Halim seeds on hyperlipidemia; this study states that Halim seeds positively impacted lipid profiles. This effect is attributed to the inhibition of an enzyme, which aids the formation of cholesterol. This indicates that the consumption of Halim seeds may help manage hyperlipidemia. However, more studies should be conducted to claim these effects with more reliability.

In my practice, I have observed that halim seeds may exhibit significant antidiarrheal properties. It is believed to achieve this by inhibiting gastrointestinal propulsion and fluid secretion, resulting in a decreased frequency of bowel movements and reduced fluid loss.

Dr. Rajeev Singh, BAMS

Other Potential Uses of Halim Seeds

Though there are studies that show the benefits of Halim seeds in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of Halim seeds on human health.  

How to Use Halim Seeds?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an Ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Halim Seeds

According to a study9, it is stated that in addition to the nutritional components, Halim seeds also contain anti-nutrients like phytates and oxalates, which may interfere with the absorption of nutrients.  

However, if you experience any adverse reactions to Halim seeds, it is advised to discontinue their intake and immediately contact a doctor or your Ayurvedic physician who has prescribed them. They will be able to guide you appropriately.

Also Read: Kayam Churna: Uses, Benefits, Side Effects and More

Precautions to Take with Halim Seeds

Consuming Halim seeds is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions8

The safety data regarding the use of Halim seeds in pregnant and breastfeeding women, the elderly and infants is limited; therefore, it is advised to take necessary cautions if you plan to add this herb to your dietary routine. It is advised to follow precautions and consume it in moderate amounts. 

Consuming Halim seeds is contraindicated in the following situations: 

Also Read: 14 Amazing Health Benefits of Pumpkin Seeds!

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Halim seeds with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking8.

Also Read: Chia Seeds: Uses, Benefits, Side Effects, and More!

Frequently Asked Questions (FAQs)

Can you use halim seeds for weight loss? 

Yes, animal studies3 show that Halim seeds may help in weight loss. However, we need more studies to support these claims in humans. Therefore, it is advised to consult a doctor for proper treatment in case you have any weight-related issues.

Can Halim seeds be used during pregnancy? 

The safety data regarding the use of Halim seeds in pregnancy is limited; therefore, it is advised to take necessary cautions if you plan to add this herb to your dietary routine. It is advised to consult a doctor for proper advice. 

Can Halim seeds be used to manage anaemia? 

Yes, Halim seeds, due to their high iron content, may help in managing iron-deficiency anemia. 

References

  1. Dixit Jr Iii, Vinti et al. “Lepidium sativum: Bone healer in traditional medicine, an experimental validation study in rats.” Journal of family medicine and primary care vol. 9,2 812-818. 28 Feb. 2020, doi:10.4103/jfmpc.jfmpc_761_19. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113932/ 
  2. AL Sayed et al. Utilization of garden cress seeds (lepidium sativum L.) as natural source of protein ‎and dietary fiber in noodles – pharmaceutical research and Allied Sciences. Available at: https://ijpras.com/article/utilization-of-garden-cress-seeds-lepidium-sativum-l-as-natural-source-of-protein-and-dietary-fiber-in-noodles (Accessed: December 13, 2022).  
  3. Azene, M., Habte, K. & Tkuwab, H. Nutritional, health benefits and toxicity of underutilized garden cress seeds and its functional food products: a review. Food Prod Process and Nutr 4, 33 (2022). Available at: https://doi.org/10.1186/s43014-022-00114-z.  
  4. Qusti, Safaa et al. “The Hypoglycemic and Antioxidant Activity of Cress Seed and Cinnamon on Streptozotocin Induced Diabetes in Male Rats.” Evidence-based complementary and alternative medicine : eCAM vol. 2016 (2016): 5614564. doi:10.1155/2016/5614564. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972928/ 
  5. Mahassni, Sawsan Hassan, and Roaa Mahdi Al-Reemi. “Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seeds.” Saudi journal of biological sciences vol. 20,2 (2013): 131-9. doi:10.1016/j.sjbs.2012.12.002. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730895/ 
  6. El-Gindy, Yassmine M et al. “Reproductive performance and milk yield of rabbits fed diets supplemented with garden cress (Lepidium sativum) seed.” Scientific reports vol. 12,1 17083. 12 Oct. 2022, doi:10.1038/s41598-022-21449-0. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556594/ 
  7. Jain, T., Grover, K. A Comprehensive Review on the Nutritional and Nutraceutical Aspects of Garden Cress (Lepidium sativum Linn.). Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci. 88, 829–836 (2018). Available at: https://doi.org/10.1007/s40011-016-0775-2 
  8. Lippert A, Renner B. Herb-drug interaction in inflammatory diseases: review of phytomedicine and herbal supplements. J Clin Med. 2022 Mar 12;11(6):1567. doi: 10.3390/jcm11061567. PMID: 35329893; PMCID: PMC8951360. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8951360/
  9. Malhotra U, Sontakke M, Shams R, Pandey VK. Effects of pre-treatments on nutritional and mineral composition of garden cress seeds (Lepidium sativum). Food Chem Adv. 2023;3(4):100398. doi:10.1016/j.focha.2023.100398. Available from: https://www.researchgate.net/publication/372523403_Effects_of_pre-treatments_on_nutritional_and_mineral_composition_of_garden_cress_seeds_Lepidium_sativum

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Ashoka Tree: Uses, Benefits, Side Effects and More!

Introduction

You would come across an Ashoka tree while walking in your building compound or on the streets. The Ashoka tree is considered sacred and legendary in India. In Sanskrit, Asoka or Ashoka means ‘without sorrow’. Ashoka is associated with several traditional beliefs and is sacred to the Hindu God of love, Kamadeva. It is believed that Gautama Siddhartha, the founder of Buddhism, was born under the Ashoka tree. The scientific name of the Ashoka tree is Saraca asoca, which belongs to the Caesalpinaceae family. Ashoka tree is native to India and is found all over India, especially in the Himalayas, Kerala, Bengal and the southern regions. The Ashoka tree has been used extensively in Ayurveda1. Let us look at some of the health benefits of the Ashoka tree. 

Nutritional Value of Ashoka Tree

Ashoka plants may contain several bioactive compounds like saponins, steroids, proteins, carbohydrates, tannins, glycosides, flavonoids, and many more1. Ashoka tree leaves and flowers may contain the following components: 

Did you know that in Sri Lanka, the traditional medicine called Asokaristha is used to tackle menstrual disorders like menorrhagia? The key component of this medicinal preparation is the bark of the Ashoka tree. However, additional studies have been conducted to understand the scientific basis behind its effectiveness10.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Ashoka Tree

Several studies have shown that the Ashoka tree may have the following properties: 

Did you know that the bark of the Ashoka tree might aid various conditions like indigestion, dysentery, piles, irregular menstruation, and sores? And guess what? The dried flowers of the tree may be used in syphilis and haemorrhage11!

Dr. Rajeev Singh, BAMS

Potential Uses of Ashoka Tree for Overall Health

Some of the potential Ashoka tree uses are: 

1. Potential Use of Ashoka Tree for Cancer

A study3 by Cibin et al. in 2012 showed that flavonoids from Ashoka tree flowers might reduce the number of tumours in skin cancer. This is because it may destabilise the free radicals (harmful molecules in the body) and reduce oxidative degradation of lipids (fats). Additionally, flavonoids from the Ashoka tree may reduce the enzymes like glutathione peroxide, catalase and ornithine decarboxylase, which may be responsible for causing skin cancer. However, these studies were conducted on animals; therefore, further studies on humans are required to check if the Ashoka tree can act against cancer. You must immediately consult your doctor if you suspect any symptoms of cancer. 

2. Potential Use of Ashoka Tree for Bacterial Infections

A study2 by Shirolkar et al. in 2012 showed that catechins in Ashoka tree bark and leaves might show antimicrobial activity. The catechins may inhibit the growth of bacteria. It may act against infections caused by bacteria like E. coli, Pseudomonas aeruginosa, Staphylococcus aureas, and many more. However, further studies are required to check if the Ashoka tree may be beneficial for bacterial infections. Therefore, you must consult your doctor if you suspect any bacterial infection. 

3. Potential Use of Ashoka Tree for Heart Diseases

A study5 by Swamy et al. in 2013 showed that bioactive compounds like β-sitosterol and epicatechin in the Ashoka tree might reduce the risk of heart disease. Ashoka tree may reduce bad cholesterol levels by destabilizing the body’s free radicals (harmful molecules) and reduce oxidative degradation of lipids (fats). High cholesterol levels in the body may increase the risk of heart diseases; therefore, antioxidant activity may contribute to protecting the heart. However, further large-scale studies on humans are required to investigate if the Ashoka tree may be beneficial in reducing the risk of heart diseases. Therefore, you must immediately consult your doctor if you suspect any symptoms of heart disease. 

4. Potential Use of Ashoka Tree for Arthritis

A study4 by Gupta et al. in 2014 showed that the flavonoids like quercetin and gallic acid in the Ashoka tree may reduce inflammation caused in arthritis. The inflammation may be reduced by inhibiting the release of inflammatory cytokines (molecules in the body responsible for causing inflammation).  However, further studies are required to check if the Ashoka tree may be beneficial for arthritis. Therefore, you must consult your doctor if you suspect arthritis instead of self-medicating. 

5. Potential Use of Ashoka Tree for Stomach Ulcers

A study6 by Maruthappan et al. in 2009 showed that flowers of the Ashoka tree might help to reduce stomach ulcers. The results suggested that the Ashoka tree may reduce lesions, inflammation and acid secretion to reduce stomach ulcers. However, these studies were conducted on animals; therefore, further large-scale studies on humans are required to check if the Ashoka tree may be beneficial for stomach ulcers. You must consult your doctor if you suspect ulcers. 

6. Potential Use of Ashoka Tree for Diabetes

A study7 by Mishra et al. in 2014 showed that bioactive compounds like phytosterol, flavonoids and saponins in the Ashoka tree might be beneficial for type II diabetes. These bioactive compounds may increase the secretion of insulin (a hormone that regulates blood sugar levels). Additionally, it may reduce blood sugar levels. However, further large-scale studies on humans are required to check if the Ashoka tree may be beneficial for diabetes. You must consult your doctor if you have abnormal sugar levels. 

7. Potential Use of Ashoka Tree for Reducing Pain

A study by Verma et al. in 2010 showed that intake of leaf extracts of the Ashoka tree may help to relieve pain. The bioactive compounds like tannins, triterpenoids, saponin, flavonoids and glycosides in the Ashoka tree might help to reduce pain. However, further studies are required to check if the Ashoka tree may be beneficial in reducing pain. Therefore, you must consult your doctor if you experience pain for a prolonged period. 

8. Potential Use of Ashoka Tree for Depression

A study9 by Gill et al. in 2017 showed that flavonoids and phenols in the Ashoka tree might help to reduce depression. These bioactive compounds may increase the antioxidants in the brain and reduce oxidative stress by destabilizing harmful free radicals. This may reduce the symptoms of depression. However, further large-scale studies on humans are required to check if the Ashoka tree may be beneficial for depression. Therefore, you must consult a doctor if you suspect symptoms of depression. 

Though studies show the benefits of the Ashoka tree in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of the Ashoka tree on human health. 

It’s interesting to note that the Ashoka tree might be beneficial in detoxifying the body and naturally purifying the blood. This may help to keep skin allergies away. It’s amazing how this natural remedy offers multiple benefits for overall well-being11!

Dr. Smita barode, B.A.M.S, M.S.

How to Use Ashoka Tree?

Various parts of the Ashoka tree can be consumed in the following ways1

You must consult a qualified doctor before taking Ashoka tree in large quantities or any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor. 

Did you know that the Ashoka tree is like a superhero for your skin? Its root, bark, and seed extracts may have incredible powers to tackle a wide range of skin issues! From fighting off acne and eczema to reducing freckles and even enhancing skin complexion, this tree with its various parts might be a true skin saviour12.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

Side Effects of Ashoka Tree

Various natural preparations made from parts of the Ashoka tree has no specific side effects. However, if any reaction is noticed on using it, seek immediate medical attention. Consult your ayurvedic physician who has prescribed it to you; they will be able to identify the cause and treat it effectively. 

Also Read: Shilajit: Uses, Benefits & Side Effects By Dr. Anuja Bodhare

Precautions to Take with Ashoka Tree

The following precautions must be taken before consuming the Ashoka tree: 

It is advised to consult your doctor before consuming a preparation made from parts of the Ashoka tree if you have any pre-existing diseases. 

The Ashoka herb has special benefits for the endometrium (lining of the uterus) and uterine muscles. This might make it a helpful uterine tonic for addressing irregular menstrual cycles and avoiding miscarriages.

Dr. Ashok Pal, BAMS

Interactions with Other Drugs

There is not enough evidence on the interaction of the Ashoka tree with other drugs. Further studies on the interaction of the Ashoka tree are required. Therefore, you must consult your doctor if you are on any other medication before consuming Ashoka tree. 

Also Read: Atibala: Benefits, Side Effects, Precautions & More

Frequently Asked Questions (FAQs)

What are the Ashoka tree medicinal uses? 

There are several medicinal uses of Ashoka tree. Ashoka tree may act against cancer. It may be used for bacterial infections, arthritis, ulcers and depression. Ashoka tree may protect the heart and help to reduce blood sugar levels. Additionally, the Ashoka tree may help to relieve pain. However, you must consult your doctor if you experience symptoms of the mentioned conditions instead of self-medicating. 

How do you consume different parts of the Ashoka tree? 

Various parts of the Ashoka tree can be consumed. The bark of the Ashoka tree can be powdered and consumed with honey. The decoction of the bark of the Ashoka tree can be consumed with milk. Ashoka tree can be consumed as ayurvedic medicines in the form of Asokarishta and Asokaghrita. However, you must consult a qualified doctor before using such preparations. 

What precautions should be taken before consuming any part of the Ashoka tree? 

Pregnant and breastfeeding women should be careful before consuming any parts of the Ashoka tree. People with heart disease should also be careful before consuming any parts of the Ashoka tree. You should consult a doctor before consuming the leaf or flower of the Ashoka tree if you have any pre-existing diseases. 

What are the side effects of consuming a part of the Ashoka tree? 

Various natural preparations made from parts of the Ashoka tree have no specific side effects. However, if any reaction is noticed on using it, seek immediate medical attention. Consult your ayurvedic physician who has prescribed it to you; they will be able to identify the cause and treat it effectively. 

What is the nutritional value of the Ashoka tree?


Ashoka leaves and flowers may contain bioactive compounds like tannins, steroids, proteins, carbohydrates, saponins, glycosides, flavonoids and many more. 

References

  1. Athiralakshmy TR, Divyamol AS, Nisha P. Phytochemical screening of Saraca asoca and antimicrobial activity against bacterial species. Asian Journal of Plant Science and Research. 2016;6(2):30-6. Available from: https://www.imedpub.com/articles-pdfs/phytochemical-screening-of-saraca-asoca-and-antimicrobial-activity-against-bacterial-species.pdf 
  2. Shirolkar A, Gahlaut A, Chhillar AK, Dabur R. Quantitative analysis of catechins in Saraca asoca and correlation with antimicrobial activity. Journal of Pharmaceutical Analysis. 2013 Dec 1;3(6):421-8. Available from: https://www.sciencedirect.com/science/article/pii/S2095177913000117 
  3. Sharma M, Sharma A, Soni A, et al. Chemoprevention of skin cancer by the flavonoid fraction of Saraca asoka. J Dermatol Sci. 2009;55(3):226-34. Available from: https://www.researchgate.net/publication/26677759_Chemoprevention_of_Skin_Cancer_by_the_Flavonoid_Fraction_of_Saraca_asoka#:~:text=and%20fatty%20acids.-,…,6).%20…
  4. Ghatak A, Nair S, Vajpayee A. Evaluation of antioxidant activity, total phenolic content, total flavonoids, and LC-MS characterization of Saraca asoca (Roxb.) De.Wilde. Int J Adv Res. 2015;3(5):318-27. Available from: https://www.researchgate.net/publication/277477244_Evaluation_of_antioxidant_activity_total_phenolic_content_total_flavonoids_and_LC-MS_characterization_of_Saraca_asoca_Roxb_DeWilde
  5. Prasad S, Younis K, Yousuf O. Investigating potent cardioprotective compounds as ACE inhibitors in Saraca asoca. Toxicol Rep. 2024 Sep 10;13:101731. doi: 10.1016/j.toxrep.2024.101731. PMID: 39309635; PMCID: PMC11416659. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11416659/
  6. Mohan C, Kistamma S, Vani P, Reddy AN. Biological activities of different parts of Saraca asoca, an endangered valuable medicinal plant. Int J Curr Microbiol App Sci. 2016;5(3):269-276. Available from: https://www.ijcmas.com/5-3-2016/Ch.%20Mohan,%20et%20al.pdf
  7. Tran N, Pham B, Le L. Bioactive Compounds in Anti-Diabetic Plants: From Herbal Medicine to Modern Drug Discovery. Biology (Basel). 2020 Aug 28;9(9):252. doi: 10.3390/biology9090252. PMID: 32872226; PMCID: PMC7563488. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7563488/
  8. Ghosh A, Saha A, Ghosh D, et al. Analgesic activity of various leaf extracts of Saraca indica Linn. Pharmacognosy Res. 2014;6(2):107-10. Available from: https://www.researchgate.net/publication/256547569_Analgesic_Activity_of_Various_Leaf_Extracts_of_Saraca_indica_Linn#:~:text=Citations%20(14)-,References%20(15),%2C%202014).%20…
  9. Ahmad SR, Ghosh P. A systematic investigation on flavonoids, catechin, β‑sitosterol and lignin glycosides from Saraca asoca (ashoka) having anti‑cancer & antioxidant properties with no side effect. J Indian Chem Soc. 2021;99:100293. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0019452221002934#:~:text=Numerous%20antioxidant%20compounds%20like%20flavonoids%2C%20catechin%2C%20beta%2Dsitosterol%2C,associated%20with%20the%20development%20of%20cancer%20conditions.
  10. Middelkoop TB, Labadie RP. The action of Saraca asoca Roxb. de Wilde bark on the PGH2 synthetase enzyme complex of the sheep vesicular gland. Z Naturforsch C Biosci. 1985 Jul-Aug;40(7-8):523-6. doi: 10.1515/znc-1985-7-812. PMID: 3931371. Available from: https://pubmed.ncbi.nlm.nih.gov/3931371/
  11. Smitha GR, Thondaiman V. Reproductive biology and breeding system of Saraca asoca (Roxb.) De Wilde: a vulnerable medicinal plant. Springerplus. 2016 Nov 28;5(1):2025. doi: 10.1186/s40064-016-3709-9. PMID: 27995002; PMCID: PMC5125291. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5125291/
  12. Nyeem MA, Haque MS, Haq MO, Nuruzzaman M, Uddin H, Islam R. Ashoka (Saraca indica) as women friendly plant: A review. Natl J Adv Res. 2017;3(2):03‑07. Available from: https://www.researchgate.net/publication/355955294_Ashoka_Saraca_indica_as_women_friendly_plant_A_review

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Rambutan: Uses, Benefits, Side Effects, and More By Dr. Smita Barode

Introduction

Rambutan is a fascinating looking red spiky fruit with soft thorns in red, yellow, and green shades. It is also known as a hairy fruit. It is a tropical, ovoid shaped fruit with a red or yellow fruit wall. The Rambutan tree is originally from Malaysia, and its name is derived from the Malay word ‘rambut’ which means hair. Rambutan is popularly grown in India, Malaysia, Indonesia, Thailand, and some humid parts of the United States. The scientific name of rambutan is Nephelium lappaceum, and it belongs to the family Sapindaceae. Rambutan pulp, seeds and peel have several bioactive compounds that may benefit food, pharmaceuticals, medicine, and cosmetics advances1. Let us glance through some of the benefits of eating rambutan and experience the unique rambutan taste, characterized by its sweet and juicy profile with hints of floral notes.

Nutritional Value of Rambutan

Rambutan seeds, peel and pulp may contain several bioactive compounds like polyphenols, including ellagitannins, geraniin, corilagin, and ellagic acid. It may contain fatty acids like arachidonic acid, stearic acid, palmitic acid and many more1. Furthermore, Rambutan fruit may contain the following nutrients: 

Did you know?

Properties of Rambutan

Several studies have shown that rambutan may have the following properties: 

Rambutan seeds are roasted and eaten as snacks in the Philippines. Munching on these seeds as a morning or evening snack not only satisfies your taste buds but also offers rambutan benefits for health and well-being14.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Benefits of Rambutan For Overall Health

Some of the potential rambutan benefits are: 

1. Potential Benefits of Rambutan as an Antioxidant

Rambutan

A study3 by Hernàndez et al. in 2017 showed that rambutan might be an antioxidant. The antioxidant potential of rambutan may be due to phytochemical compounds like phenols, flavonoids, corilagin, geraniin, and ellagic acid. These compounds may deactivate the free radicals (harmful molecules present in the body) and protect the body from various damages. 

2. Potential Benefits of Rambutan for Cancer

cancer

A study by Perumal et al. in 2020 showed that rambutan might act against breast, bone, cervical and liver cancer. The anticancer activity of rambutan may be due to bioactive compounds like flavonoids, alkaloids, tannins, terpenoids and other phenolic compounds like geraniin. Rambutan benefits may show apoptosis (kill the cancer cells) and inhibit their growth. However more studies are required to check if rambutan can be used against cancer. Cancer is a serious disease therefore, you must consult your doctor if you suspect cancer instead of self-medicating. 

3. Potential Benefits of Rambutan for Reducing Sugar Levels

regulates blood sugar

Rambutan is a delicious tropical fruit that might offer potential benefits for diabetes management. A study by Muhtadi et al. in 2016, conducted on rats, suggested that bioactive compounds found in rambutan, such as catechin, quercetin, polyphenols, geraniin, and tannins, could contribute to reducing blood sugar levels. These compounds may help inhibit glucose absorption by the cells and stimulate insulin secretion, potentially assisting in the maintenance of normal blood sugar levels. It’s important to note that this study was conducted on animals, and further research on humans is needed to confirm the potential rambutan benefits for diabetes. If you have diabetes it’s essential to monitor your blood sugar levels regularly and consult with your healthcare provider for appropriate guidance.

4. Potential Benefits of Rambutan for Dengue

mosquito

A study6 by Ahmad et al. in 2015 showed that geraniin in rambutan might have anti-viral activity and act against DENV-2 (dengue virus type-2). Geraniin may inhibit the attachment of the dengue virus to the body cells and may also interfere with a viral protein (E protein) to disrupt the infection process. However, further studies are required to check if rambutan may act against the dengue virus. Therefore you must immediately consult your doctor if you suspect any symptoms of dengue. 

5. Potential Benefits of Rambutan to Reduce Inflammation

reduces inflammation

A study7 by Chingsuwanrote et al. in 2015 showed that the polyphenols in rambutan might reduce inflammation. The polyphenols may inhibit the secretion of TNFα, an inflammatory cytokine (molecules in the body responsible for inflammation). However, more studies are required to check if rambutan has anti-inflammatory properties. 

6. Potential Benefits of Rambutan for Bacterial Infections

infection

A study8 by Phuong et al. in 2020 showed that bioactive compounds in rambutan, like tannins, corilagin, geraniins, and ellagic acid, may possess antibacterial activity. Various bioactive compounds have different ways of showing their antibacterial activity. Tannins may change the structure of the cell wall and cell membrane. Ellagic acid may attach to the cell wall and destabilize it. Corilagin may inhibit the growth of bacteria by disrupting cell permeability. However, more large scale studies are required to check the antibacterial effect of rambutan. Therefore you must consult your doctor if you suspect a microbial infection. 

7. Potential Benefits of Rambutan for Controlling Blood Pressure

A study9 by Fang et al in 2018 suggested that rambutan fruit benefits might extend to lowering blood pressure. Specifically, geraniin found in rambutan may play a role in reducing blood pressure by decreasing the release of noradrenaline (a hormone that increases blood pressure) and relaxing tension in the blood vessels. Further research involving human subjects is needed to confirm these effects. It’s essential to consult your doctor if you have abnormal blood pressure instead of attempting self-medication.

Though studies show the benefits of rambutan in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of rambutan on human health. 

Researchers are evaluating the anti-HIV, anti-dengue and anti-allergic properties of Rambutan. These activities have been observed during lab trials more research is needed to support these claims14.

Dr. Rajeev Singh, BAMS

How to Use Rambutan?

Rambutan can be consumed in the following way: 

You must consult a qualified doctor before taking large quantities of Rambutan or other herbal supplements. Likewise, do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor. 

Side Effects of Rambutan

Rambutan side effects are reported as follows: 

If you notice any reaction by consuming rambutan, seek immediate medical attention. First, consult your ayurvedic physician who has prescribed it to you; they will be able to identify the cause and treat it. 

Precautions to Take with Rambutan

The following precautions can be taken before consuming rambutan: 

It is advised to consult your doctor before consuming if you have any pre-existing diseases. 

Conclusion

There is not enough evidence on the interaction of rambutan with other drugs. Further studies on the interaction of rambutan are required. Therefore you must consult your doctor if you are on any other medication before consuming rambutan. 

Frequently Asked Questions (FAQs)

What are Rambutan fruit side effects? 

Rambutan may cause nausea and vomiting, angioedema (swelling of the lower layer of skin), urticaria (swollen, reddened, and itchy skin), flushing of the skin (sudden redness of the skin), chest tightness, and wheezing11

Is Rambutan good for diabetes? 

Bioactive compounds in rambutan, like catechin, quercetin, polyphenols, geraniin, and tannins, may help to reduce blood sugar5. However, you must check your blood sugar levels regularly and consult your doctor in case of abnormal blood sugar levels

What precautions must be taken with Rambutan?

Rambutan is considered safe, but pregnant and breastfeeding mothers shall take precautions before consuming rambutan12. Saponins and tannins are phytochemicals, and they are biologically active compounds. But in a few cases, saponins and tannins may be toxic to a few people. In addition, rambutan seeds may be narcotic (causes sleepiness and affects mood)13. It is advised to consult your doctor if you have any pre-existing diseases before consuming. 

Can Rambutan seeds be eaten?

Rambutan seeds are generally not recommended for consumption as they can be bitter and potentially toxic. It’s advisable to consult with a healthcare professional for personalized guidance regarding your dietary choices and potential risks associated with consuming rambutan seeds.

Can Rambutan cause sore throat?

While rambutan consumption is not commonly associated with sore throat, individual reactions may vary. If you experience a sore throat after consuming rambutan or suspect any adverse reactions, it’s advisable to consult with a healthcare professional for a personalized assessment and guidance.

Can Rambutan make you sick?

Consuming rambutan is generally safe for most individuals. However, if you experience digestive discomfort, allergies, or any adverse reactions after consuming rambutan, it’s advisable to consult with a healthcare professional for a proper assessment and personalized guidance to determine the cause of the illness.

Can Rambutan increase uric acid?

Rambutan is not a known food source that significantly increases uric acid levels. However, individual reactions can vary, and those with gout or uric acid concerns should consume it in moderation and monitor their own body’s response. If you have specific health concerns, consulting a healthcare professional is advisable for personalized guidance.

Are Rambutans good for dogs?

Rambutan should be avoided for dogs as it can pose a choking hazard due to its large seed and may not provide significant nutritional benefits for them. It’s best to consult with a veterinarian for guidance on safe and appropriate treats for your pet.

Can Rambutan cause stomach pain?

Rambutan is typically safe to eat, but for some individuals, overconsumption or sensitivity to certain compounds in the fruit might lead to stomach discomfort or pain. If you experience stomach pain after consuming rambutan, consult a healthcare professional to rule out any allergies or sensitivities and to ensure it aligns with your dietary choices.

Can Rambutan cause constipation?

While rambutan is generally not associated with causing constipation, excessive consumption or dietary factors could potentially lead to this issue in some individuals. If you encounter constipation after eating rambutan, consult a healthcare professional to assess your dietary choices and address any underlying causes.

Can Rambutan cause acne?

Rambutan is not commonly linked to causing acne. However, an individual’s skin reactions can vary, and it’s possible that consuming rambutan, especially in excessive amounts, might lead to skin issues for some people. Consulting a healthcare professional or dermatologist can help identify any specific triggers and address potential skin concerns.

Can Rambutan cause cough?

Rambutan is not a known cause of cough. Coughing can result from various factors such as infections, allergies, or irritants. If you experience persistent coughing after consuming rambutan, consult a healthcare professional to rule out any allergies or underlying respiratory issues.

Can Rambutan cause miscarriage?

There is no scientific evidence to suggest that rambutan can cause a miscarriage. However, during pregnancy, it’s crucial to be cautious about your dietary choices and consult a healthcare professional for guidance on safe and healthy eating practices to support a healthy pregnancy.

Can Rambutan cause diarrhea?

Rambutan consumption is generally safe, but excessive intake may lead to diarrhea in some individuals due to its natural sugars and dietary fiber. If you experience persistent or severe diarrhea after eating rambutan, consult a healthcare professional to assess any underlying issues and ensure proper hydration and dietary choices.

How to eat Rambutan?

To eat rambutan, start by making a shallow cut around the circumference of the fruit’s skin, being careful not to cut too deep. Then, gently twist the fruit open, revealing the juicy flesh inside. Remove the seed and enjoy the sweet and slightly tangy fruit.

Is Rambutan a tree nut?

No, rambutan is not a tree nut. It is a tropical fruit belonging to the Sapindaceae family and is botanically related to lychee and longan. While it may trigger allergies in some individuals, it is not classified as a tree nut allergen.

References

  1. Hernández-Hernández C, Aguilar CN, Rodríguez-Herrera R, Flores-Gallegos AC, Morlett-Chávez J, Govea-Salas M, Ascacio-Valdés JA. Rambutan (Nephelium lappaceum L.): Nutritional and functional properties. Trends in food science & technology. 2019 Mar 1;85:201-10. Available from: https://www.researchgate.net/publication/391314241_Antiviral_Activity_of_Rambutan_Peel_Polyphenols_Obtained_Using_Green_Extraction_Technology_and_Solvents
  2. Rambutan, canned, syrup pack [Internet]. FoodData Central. [cited 2022Dec1]. Available from: https://fdc.nal.usda.gov/fdc-app.html#/food-details/168167/nutrients 
  3. Hernández C, Ascacio-Valdés J, De la Garza H, Wong-Paz J, Aguilar CN, Martínez-Ávila GC, Castro-López C, Aguilera-Carbó A. Polyphenolic content, in vitro antioxidant activity and chemical composition of extract from Nephelium lappaceum L.(Mexican rambutan) husk. Asian Pacific Journal of Tropical Medicine. 2017 Dec 1;10(12):1201-5. Available from: https://www.sciencedirect.com/science/article/pii/S1995764517311641 
  4. Perumal A, AlSalhi MS, Kanakarajan S, Devanesan S, Selvaraj R, Tamizhazhagan V. Phytochemical evaluation and anticancer activity of rambutan (Nephelium lappaceum) fruit endocarp extracts against human hepatocellular carcinoma (HepG-2) cells. Saudi Journal of Biological Sciences. 2021 Mar 1;28(3):1816-25. Available from: https://www.sciencedirect.com/science/article/pii/S1319562X2030680X 
  5. Muhtadi M, Haryoto H, Sujono TA, Suhendi A. Antidiabetic and antihypercholesterolemia activities of rambutan (Nephelium lappaceum L.) and durian (Durio zibethinus Murr.) fruit peel extracts. Journal of Applied Pharmaceutical Science. 2016 Apr 30;6(4):190-4. Available from: https://japsonline.com/admin/php/uploads/1848_pdf.pdf 
  6. Ahmad SA, Palanisamy U, Tejo BA, Hassan SS. Geraniin extracted from the Nephelium lappaceum (rambutan) rind inhibits dengue virus type-2. International conference and expo on drug discovery and designing, Frankfurt 2015. Available from: https://www.longdom.org/conference-abstracts-files/2169-0138.S1.008-024.pdf 
  7. Chingsuwanrote P, Muangnoi C, Parengam K, Tuntipopipat S. Antioxidant and anti-inflammatory activities of durian and rambutan pulp extract. International Food Research Journal. 2016 Aug 1;23(3). Available from: http://www.ifrj.upm.edu.my/23%20(03)%202016/(5).pdf 
  8. Phuong NN, Le TT, Van Camp J, Raes K. Evaluation of antimicrobial activity of rambutan (Nephelium lappaceum L.) peel extracts. International journal of food microbiology. 2020 May 16;321:108539. Available from: https://www.sciencedirect.com/science/article/pii/S0168160520300337 
  9. Phang SC, Palanisamy UD, Kadir KA. Effects of geraniin (rambutan rind extract) on blood pressure and metabolic parameters in rats fed high-fat diet. Journal of integrative medicine. 2019 Mar 1;17(2):100-6. Available from: https://www.sciencedirect.com/science/article/pii/S2095496419300081 
  10. Thulaja NR. Rambutan [Internet]. Infopedia. [cited 2022Dec1]. Available from: https://www.nlb.gov.sg/main/article-detail?cmsuuid=f5af61c8-6be6-4ec3-bc4e-d6a4c08c55b8
  11. Jirapongsananuruk O, Jirarattanasopa N, Pongpruksa S, Vichyanond P, Piboonpocanun S. Glyceraldehyde-3-phosphate dehydrogenase as a major allergen in rambutan-induced anaphylaxis. Annals of Allergy, Asthma & Immunology. 2011 Jun 1;106(6):545-7. Available from: https://www.annallergy.org/article/S1081-1206(11)00188-8/abstract 
  12. Diana R, Rachmayanti RD, Anwar F, Khomsan A, Christianti DF, Kusuma R. Food taboos and suggestions among Madurese pregnant women: a qualitative study. Journal of Ethnic Foods. 2018 Dec 1;5(4):246-53. Available from: https://www.sciencedirect.com/science/article/pii/S2352618118301446 
  13. Rambutan Nephelium lappaceum L. Euphoria nephelium DC. Dimocarpus crinita Lour. [Internet]. Rambutan. [cited 2022Dec2]. Available from: https://www.hort.purdue.edu/newcrop/morton/rambutan.html
  14. Afzaal M, Saeed F, Bibi M, Ejaz A, Shah YA, Faisal Z, Ateeq H, Akram N, Asghar A, Shah MA. Nutritional, pharmaceutical, and functional aspects of rambutan in industrial perspective: An updated review. Food Sci Nutr. 2023 Apr 19;11(7):3675-3685. doi: 10.1002/fsn3.3379. PMID: 37457167; PMCID: PMC10345721. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10345721/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Mango (Aam): Uses, Benefits, Side Effects by Dr. Smita Barode

Introduction

Mangoes and summer seasons are a match made in heaven! The sweet and juicy taste coupled with countless health benefits justify why mango is called the “king of fruits”. Mangifera indica, mango or aam, is an important fruit in Ayurveda. It belongs to the genus Mangifera, and family Anacardiaceae which contains 30 different species. India ranks first among the major mango-producing countries. India is famous for its wide range of mango varieties, like Alphonso variety of Ratnagiri, Badami variety of Karnataka, Dasheri variety of Lucknow and Kesar variety of Gujarat to name a few. Mangoes are good for our taste buds and our health. They are also a rich source of fibre, vitamins, minerals and antioxidants like mangiferin and glucosyl xanthone. Let us read more about some mango benefits1

Nutritional Value of Mango

Mango (Aam) is packed with various nutritional components that are given as follows. They are a good source of vitamins, minerals and antioxidants like mangiferin and glucosyl xanthone, and carotenes. 

In my opinion, eating mangoes might be a way of giving your body a natural defence against certain diseases. Mangoes might have superpowers against certain types of cancers. Yes, it’s true! Thanks to the magical combination of beta-carotene and other special substances, mangoes might help against leukaemia and even slow down the progression of prostate and colon cancers11.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Mango

The mango shows numerous scientifically proven properties; some of these properties are mentioned below: 

Potential Uses of Mango for Overall Health

Some of the potential benefits of mango are described as follows: 

1. Potential Uses of Mango for Breast Cancer

breast cancer

Breast cancer is one of the most common cancers, leading to pre-mature death of females globally. Natural products are now becoming important sources for the discovery of anti-cancer agents. Mangifera indica may have the potential for the management of breast cancers. Banerjee et al. conducted a study in 2015 to assess the effect of mangoes on breast cancer xenografts in mice. This study3 showed that polyphenols like gallic acid, galloyl glycosides and gallotannins in mangoes might have a chemotherapeutic potential against breast cancer. This indicates that mangoes may help in managing breast cancer. However, more studies are required to support these claims. 

2. Potential Uses of Mango in Ulcerative Colitis 

mango

Ulcerative colitis is a chronic inflammatory condition affecting the colon and rectum. Mangoes may help in reducing inflammation because of the presence of polyphenols like gallotannins and gallic acid. Kim et al. conducted a study4 in 2016 to assess mango’s anti-inflammatory effects in a preclinical colitis model. The results of this study4 showed that mango consumption might help in managing ulcerative colitis. However, more human studies are required to ascertain these claims. 

From my perspective, eating mangoes can be a tasty solution to help with constipation. In a study12, it was found that munching on mangoes might actually improve the symptoms of constipation. Thus, mangoes may be a delicious way to keep things flowing smoothly in your digestive system.

Dr. Smita Barode, B.A.M.S, M.S.

3. Potential Uses of Mango for Managing Blood Glucose 

regulates blood sugar

Fruits and vegetables are a rich source of bioactive compounds which may help in managing the blood glucose level. The study conducted by Evans et al. 2014 showed that mangoes may reduce blood glucose levels in both females and males. The mango contains tocopherols, carotenoids, dietary fibre, ascorbic acid, gallic acid, quercetin and mangiferin. These biologically active compounds may help in normalising blood glucose levels. However, to claim all these benefits further research and confirmation are needed. If you suspect high blood glucose levels, consult your doctor and do not self-medicate5

4. Potential Uses of Mango for Skin and Hair 

Mangoes, if consumed in moderate amounts, may help achieve healthy hair and nourished skin due to its high Vitamin A content. Additionally, mangoes may act as a natural sunblock by protecting our skin and hair from damage caused due to ultraviolet rays. Therefore, there is a possibility that the consumption of mango can benefit skin and hair, but we need more human studies6 to support these claims. If you have any skin and hair related problems, consult a doctor and do not self-medicate. 

5. Potential Uses of Mango for Managing Macular Degeneration 

eye

Macular degeneration is a common eye disorder which causes vision loss. Mangoes are rich in antioxidants like lutein, zeaxanthin and Vitamin A, which may help deal with macular degeneration. Mango is also rich in carotene which may help in vision. Thus, it may indicate that consuming mango may help manage macular degeneration. However, there is a lack of studies6 to support these claims. 

6. Potential Uses of Mango on Nutrient Intake 

Mango

Mangoes are a good source of nutrients in the diet. The nutrient intake of mango consumers vs. non-consumers was obtained from the NHANES database. It was observed that people who consumed mangoes had a higher intake of magnesium, potassium, folate, Vitamin A, C and E and dietary fibre compared to the non-consumers. This may indicate that the consumption of mangoes can help improve nutrient intake and diet quality. However, more studies7 need to be conducted to support these claims. 

7. Other Potential Uses of Mango

weight loss

Though there are studies that show the benefits of Mango in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of Mango on human health.  

Let me tell you a secret. Mangoes are not just delicious; they’re also packed with a special ingredient called mangiferin! This fancy-sounding compound can be found in various parts of the mango fruit, like the peel, stalks, leaves, barks, kernel, and even the stone. Mangiferin might be just the secret weapon as it is high in antioxidants13.

Dr. Rajeev Singh, BAMS

How to Use Mango?

This super versatile fruit can be used in the following ways: 

You must consult a qualified doctor before taking any herbal supplements or mangoes in large quantities. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Also Read: Jackfruit (Kathal): Uses, Benefits, Side Effects and More!

Side Effects of Mango

A few side effects related to the consumption of mango include: 

However, if you experience any adverse reactions to mango, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it to you. They will be able to guide you appropriately for your symptoms. 

Precautions to Take with Mango

Eating mango is beneficial if taken in moderate amounts. However, general precautions must be followed in the given conditions: 

Also Read: Water Apple: Uses, Benefits, Side Effects, And More!

Interactions with Other Drugs

Mangoes inhibit the cytochrome P450 enzymes, which are known to metabolize certain drugs like warfarin, propranolol, theophylline, etc. Inhibition of these enzymes can alter the blood concentration of drugs metabolized by this pathway. Therefore, you must always seek the advice of your Ayurvedic physician about the possible interaction of raw mangoes with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking10

Frequently Asked Questions (FAQs)

What is the scientific name of mango (Aam)? 

The scientific name of mango is Mangifera Indica and it belongs to the family Anacardiaceae1

Can mango help in breast cancer? 

Animal cell line studies support the use of mangoes for managing breast cancers. However, more studies are needed to claim these effects. Thus, it is recommended to consult a doctor for proper treatment3

Which fruit is known as the king of fruits?  

Mango is also known as the “king of fruits”1

Can mango help improve vision? 

Yes. As mango is a rich source of Vitamin A, it may improve vision. However, it is advised to consult a doctor for proper diagnosis for vision-related problems and not consider the consumption of mango as an alternative to modern medicine6

What are the side effects of mango consumption? 

Consumption of mangoes in excess can cause short-term gastrointestinal disorders like stomach pain and diarrhoea and allergies in allergy-prone individuals10

References

  1. Shah KA, Patel MB, Patel RJ, Parmar PK. Mangifera indica (mango). Pharmacogn Rev. 2010 Jan;4(7):42-8. doi: 10.4103/0973-7847.65325. PMID: 22228940; PMCID: PMC3249901. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249901/ 
  1. Lauricella, Marianna et al. “Multifaceted Health Benefits of Mangifera indica L. (Mango): The Inestimable Value of Orchards Recently Planted in Sicilian Rural Areas.” Nutrients vol. 9,5 525. 20 May. 2017, doi:10.3390/nu9050525. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452255/ 
  1. Banerjee Nivedita, Kim Hyemee, Krenek Kimberly, Talcott Stephen T., Mertens-Talcott Susanne U., Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: Role of the PI3K/AKT pathway and associated microRNAs, Nutrition Research (2015), doi: 10.1016/j.nutres.2015.06.00. Available at: https://www.sciencedirect.com/science/article/abs/pii/S0271531715001360 
  1. Kim, Hyemee et al. “Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis.” Molecular nutrition & food research vol. 60,9 (2016): 1912-23. doi:10.1002/mnfr.201501008. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026564/ 
  1. Evans, Shirley F et al. “Mango supplementation improves blood glucose in obese individuals.” Nutrition and metabolic insights vol. 7 77-84. 28 Aug. 2014, doi:10.4137/NMI.S17028. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155986/  
  1. Garg, D.P. (2022) 9 health benefits of mangoes – weight loss, immunity, good for skin & more – pharmeasy, PharmEasy Blog. Available at: https://pharmeasy.in/blog/health-benefits-of-mangoes/ (Accessed: November 25, 2022). 
  1. Papanikolaou, Yanni, and Victor L Fulgoni 3rd. “Mango Consumption Is Associated with Improved Nutrient Intakes, Diet Quality, and Weight-Related Health Outcomes.” Nutrients vol. 14,1 59. 24 Dec. 2021, doi:10.3390/nu14010059. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746860/ 
  1. O’Hara, Crystal et al. “Acute Freeze-Dried Mango Consumption With a High-Fat Meal has Minimal Effects on Postprandial Metabolism, Inflammation and Antioxidant Enzymes.” Nutrition and metabolic insights vol. 12 1178638819869946. 19 Aug. 2019, doi:10.1177/1178638819869946. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700848/ 
  1.  Singh, S. (2022) Mango benefits: 25 healthy reasons to eat mangoes – fitelo, Mango Benefits 25 Healthy Reasons To Eat Mangoes Comments. Available at: https://fitelo.co/mango-benefits/ (Accessed: November 25, 2022).   
  1. Rodríguez-Fragoso, L., Martínez-Arismendi, J.L., Orozco-Bustos, D., Reyes-Esparza, J., Torres, E. and Burchiel, S.W. (2011), Potential Risks Resulting from Fruit/Vegetable–Drug Interactions: Effects on Drug-Metabolizing Enzymes and Drug Transporters. Journal of Food Science, 76: R112-R124. Available at: https://ift.onlinelibrary.wiley.com/doi/10.1111/j.1750-3841.2011.02155.x 
  2. Lebaka VR, Wee YJ, Ye W, Korivi M. Nutritional Composition and Bioactive Compounds in Three Different Parts of Mango Fruit. Int J Environ Res Public Health. 2021 Jan 16;18(2):741. doi: 10.3390/ijerph18020741. PMID: 33467139; PMCID: PMC7830918. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7830918/
  3. Venancio VP, Kim H, Sirven MA, Tekwe CD, Honvoh G, Talcott ST, Mertens-Talcott SU. Polyphenol-rich Mango (Mangifera indica L.) Ameliorate Functional Constipation Symptoms in Humans beyond Equivalent Amount of Fiber. Mol Nutr Food Res. 2018 Jun;62(12):e1701034. doi: 10.1002/mnfr.201701034. Epub 2018 May 29. PMID: 29733520. Available at: https://pubmed.ncbi.nlm.nih.gov/29733520/
  4. Imran M, Arshad MS, Butt MS, Kwon JH, Arshad MU, Sultan MT. Mangiferin: a natural miracle bioactive compound against lifestyle related disorders. Lipids Health Dis. 2017 May 2;16(1):84. doi: 10.1186/s12944-017-0449-y. PMID: 28464819; PMCID: PMC5414237. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5414237/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Hibiscus Tea: Uses, Benefits, Side Effects By Dr. Smita Barode

Introduction

Ruby red-coloured hibiscus tea is often consumed as an alternative to regular tea and coffee. It is refreshing and has a tangy flavour. Hibiscus is found in several warm countries like India, Thailand, Vietnam, Mexico, Saudi Arabia, Malaysia, Sudan, Egypt, Philippines, and Indonesia. The scientific name of the hibiscus is Hibiscus sabdariffa, and it belongs to the family Malvaceae. Hibiscus is commonly known as ‘roselle’ or ‘red sorrel.’ The fleshy red calyx of hibiscus is often used to make hibiscus tea. Hibiscus is a caffeine-free herbal tea that tastes like berries1. Let us look at some hibiscus tea health benefits.

Nutritional Value of Hibiscus Tea

Brewed hibiscus tea nutrition is as follows2:  

Furthermore, hibiscus has several bioactive compounds like anthocyanin, organic acids, triterpenoids, flavonoids, alkaloids, steroids, carotene, and many more1

Properties of Hibiscus Tea

Several studies have shown that hibiscus tea properties may be as follows1:  

Potential Uses of Hibiscus Tea for Overall Health

Some of the potential hibiscus tea uses are: 

1. Potential Use of Hibiscus Tea for Lowering Blood Sugar Levels 

regulates blood sugar
Image Source: freepik.com

A study3  by Jamrozik et al. in 2022 showed that the polyphenols in hibiscus tea might lower blood sugar levels by inhibiting enzymes like α-glucosidase and α-amylase. These enzymes are responsible for digesting carbohydrates and increasing glucose levels after consuming food.However, further studies on humans are required to check if hibiscus tea may help to lower blood sugar levels. Therefore, you must check your blood sugar levels regularly and immediately consult the doctor in case of abnormal sugar levels. 

2. Potential Use of Hibiscus Tea for Lowering Blood Pressure 

high blood pressure
Image Source: freepik.com

A study4 by McKay et al. in 2009 showed that flavonoids like delphinidin-3-sambubioside and cyanidin-3-sambubioside present in hibiscus tea might reduce blood pressure. Hibiscus is a vasorelaxant as it relaxes the tension on the walls of blood vessels; therefore, it may lower blood pressure. However, more studies on humans are required to check if hibiscus tea may lower blood pressure. Therefore, you must check your blood pressure and consult your doctor in case of abnormal blood pressure. 

3. Potential Use of Hibiscus Tea for Lowering Cholesterol 

Cholesterol normal range
Image Source: freepik.com

A study5 by Sanadheera et al. in 2021 showed that hibiscus tea might reduce bad cholesterol levels (total cholesterol, low-density lipoprotein, and very low-density lipoprotein). Additionally, it may elevate good cholesterol levels (high-density lipoprotein). This may be due to the antioxidant properties of hibiscus tea. However, more studies on humans are yet to be done to check if hibiscus tea may affect cholesterol levels. Therefore, you must check your cholesterol levels and consult your doctor if you have abnormal cholesterol levels. 

4. Potential Use of Hibiscus Tea for Reducing Inflammation 

reduces inflammation
Image Source: freepik.com

A study6 by Raduan et al. in 2013 showed that saponins, flavonoids, and plant sterols might reduce inflammation. Hibiscus tea may inhibit cyclooxygenase. Cyclooxygenase is an enzyme that elevates the levels of prostaglandins (lipids responsible for inflammation). However, more studies on humans are yet to be done to check if hibiscus tea may reduce inflammation. You must consult your doctor if you suspect inflammation in your body. 

5. Potential Use of Hibiscus Tea for Weight Management 

weight loss
Image Source: freepik.com

A study7 by F.J. Alarcon-Aguilar et al. in 2007 on mice showed that anthocyanin, cyanidin, and delphinidin in hibiscus tea might reduce weight. Hibiscus tea may reduce weight by reducing the levels of cholesterol and by inhibiting the gastric and pancreatic lipases responsible for increasing the fat levels in the body.7 However, this is the result of animal studies; more studies on humans are required. You must consult your dietitian before making any essential changes to your diet. 

6. Potential Use of Hibiscus Tea for Microbial Infections 

infection
Image Source: freepik.com

A study10 showed that hibiscus tea might possess antibacterial and antifungal activity. Hibiscus tea may possess activity against Streptococcus mutans, a bacterium from the oral cavity, Schistosoma mansoni, and Campylobacter species. In addition, hibiscus tea may reduce the formation of aflatoxin, a toxin produced by fungi. However, more studies on humans are required to check if hibiscus tea may be beneficial for microbial infections. Therefore, you must consult your doctor if you suspect a microbial infection. 

7. Potential Use of Hibiscus Tea for Cancer 

Image Source: freepik.com

A study8 by Lin et al. in 2011 showed that hibiscus tea might act against cancer. The polyphenols, like catechin, may be an antioxidants and act against free radicals. Additionally, the polyphenols may inhibit prostate tumours and deactivate the cancerous cells. However, more studies on humans are required to check the anti-cancer effect of hibiscus tea. Therefore, you must immediately consult your doctor if you suspect it instead of self-medicating. 

Though studies show the benefits of hibiscus tea in various conditions, these are insufficient, and further studies are to establish the true extent of the benefits of hibiscus tea on human health. 

How to Use Hibiscus Tea

Here’s a quick and easy hibiscus tea recipe to follow:

You must visit a doctor before taking hibiscus tea in large quantities or any herbal products. Do not discontinue or replace an ongoing treatment of modern medicine or herbal preparation without consulting a doctor. 

Also Read: Instant Home Remedies for Digestive Problems

Side Effects of Hibiscus Tea

Studies1 have shown that hibiscus tea is considered safe when consumed adequately. A few hibiscus tea side effects may be gas, upset stomach, and constipation9. If you notice any reaction to consuming hibiscus tea, seek immediate medical attention. Consult your ayurvedic physician who has prescribed it to you. 

1. Estrogen Levels

2. Effects on Kidneys

3. Gas, Upset Stomach, and Constipation

4. General Recommendations

Also Read: Natural Home Remedies For Grey Hair

Precautions to Take with Hibiscus Tea

The following precautions shall be taken before consuming hibiscus tea: 

It is advised to consult your doctor before consuming hibiscus tea if you have any pre-existing diseases. 

Interactions with Other Medicines

Hibiscus tea may interact with the following medicines

You must consult a doctor before taking hibiscus tea if you are undergoing medical treatment.

Also Read: Everyday Benefits of Jeera Water That You Should Know!

Frequently Asked Questions (FAQs)

What are the uses of hibiscus tea? 

Hibiscus tea helps lower blood sugar levels, cholesterol, and blood pressure. It may reduce inflammation, help manage weight, and act against microbial infections. In addition, it may act as an antioxidant and reduce cancer risk. However, you must visit your doctor if you have any of the mentioned conditions instead of self-medicating. 

What vitamins are present in hibiscus tea?

Hibiscus tea contains various vitamins, including vitamin C, which contributes to immune support and skin health. Additionally, it provides traces of vitamin A and vitamin B, enhancing its nutritional profile.

What antioxidants are in hibiscus tea?

Hibiscus tea boasts a rich antioxidant profile, featuring anthocyanins that contribute to its vibrant colour and help combat oxidative stress. These antioxidants may provide potential health benefits, such as supporting heart health and reducing inflammation.

Is hibiscus tea acidic?

Yes, hibiscus tea is slightly acidic due to its natural compounds. However, it’s generally considered safe for most people, but individuals with acid sensitivity may want to consume it in moderation.

Is hibiscus tea good for the kidneys?

Hibiscus tea benefits may include supporting kidney health, as it has been associated with lowering blood pressure and reducing oxidative stress. However, individuals with pre-existing kidney conditions should consult with a healthcare professional before incorporating it into their diet.

Is hibiscus tea good for periods?

While some believe hibiscus tea may help relieve menstrual cramps and promote a healthy menstrual cycle due to its reported anti-inflammatory properties, scientific evidence is limited. Individuals seeking relief for period-related discomfort should consult with a healthcare professional for personalised advice.

Is hibiscus tea good for gastritis?

Hibiscus tea might aggravate gastritis symptoms for some individuals due to its natural acidity. It’s advisable for those with gastritis to consult with a healthcare professional to determine whether hibiscus tea is suitable for their specific condition.

Is hibiscus tea contain caffeine?

Hibiscus tea is caffeine-free, making it a suitable choice for individuals looking to avoid or limit caffeine intake. It offers a refreshing option for those seeking a beverage without the stimulating effects of caffeine.

Is hibiscus tea good for PCOS?

Hibiscus tea may be beneficial for individuals with Polycystic Ovary Syndrome (PCOS) as it could potentially help regulate blood pressure and manage insulin resistance. However, individual responses vary, and consulting with a healthcare professional for personalised advice is recommended for those with PCOS.

Is hibiscus tea good for hair growth?

While hibiscus tea is rich in antioxidants that may promote scalp health, scientific evidence on its direct impact on hair growth is limited. For optimal hair growth, it’s crucial to maintain a well-balanced diet and consider consulting with a healthcare professional for personalized advice.

Can I drink hibiscus tea in the morning?

Absolutely, you can enjoy hibiscus tea in the morning. Its caffeine-free nature makes it a refreshing and suitable beverage to start your day, offering a burst of flavour without the stimulating effects of caffeine.

Can I drink hibiscus tea while breastfeeding?

While hibiscus tea is generally considered safe, breastfeeding individuals should consume it in moderation due to limited research on its effects during lactation. It’s advisable to consult with a healthcare professional before including hibiscus tea in your diet while breastfeeding.

Can I drink hibiscus tea on an empty stomach?

Certainly, drinking hibiscus tea on an empty stomach is generally fine for most people. However, individual reactions vary, so it’s wise to monitor how your body responds. If you experience any discomfort, consider consulting with a healthcare professional for personalised advice.

Can you eat hibiscus tea leaves?

Consuming hibiscus tea leaves is generally not recommended, as they can be tough and have a strong, concentrated flavour. If you’re considering incorporating hibiscus into your diet, it’s advisable to seek guidance from a healthcare professional to ensure safe and suitable consumption.

Can I drink hibiscus tea while fasting?

Yes, you can drink hibiscus tea while fasting. Its lack of calories and potential health benefits make it a suitable beverage during fasting periods. However, individual responses vary, so it’s advisable to consult with a healthcare professional, especially if you have specific health concerns or conditions.

Is hibiscus tea good for gut health?

Hibiscus tea may support gut health due to its anti-inflammatory and antioxidant properties. However, individual reactions vary, and it’s advisable to consult with a healthcare professional for personalised advice on incorporating hibiscus tea for gut health.

What does hibiscus tea taste like?

Hibiscus tea boasts a unique flavour profile characterised by its tart and slightly fruity notes. Its vibrant crimson hue complements its refreshing taste, offering a delightful balance of sweetness and acidity.

Is hibiscus tea good for skin?

Hibiscus tea is considered beneficial for the skin due to its antioxidant-rich composition, potentially supporting a healthy complexion and combating free radicals. However, it’s essential to consult with a healthcare professional for personalised advice on integrating hibiscus tea into your skincare routine.

Is hibiscus tea good for fatty liver?

Hibiscus tea benefits may include supporting a fatty liver as it has been linked to liver health support and lipid metabolism. Nevertheless, it’s crucial to seek guidance from a healthcare professional for personalised advice tailored to individual health conditions and needs.

 Is hibiscus tea good for the thyroid?

While hibiscus tea is generally considered safe, excessive consumption may interfere with thyroid function due to its iodine content. It’s crucial to consult with a healthcare professional for personalised advice, especially if you have thyroid issues, to ensure it aligns with your specific health needs.

Can hibiscus tea be taken at night?

Yes, hibiscus tea can be consumed at night. It is caffeine-free and may promote relaxation, making it a suitable choice before bedtime. However, individual responses may vary, so it’s advisable to monitor how your body reacts to it.

Can hibiscus tea irritate the bladder?

Hibiscus tea is mildly acidic and may potentially irritate the bladder in some individuals. If you have a history of bladder issues, it’s recommended to monitor your body’s response and consult with a healthcare professional for personalised advice.

Can hibiscus tea make you sleepy?

Hibiscus tea is caffeine-free and contains compounds that may have a mild sedative effect, potentially promoting relaxation and aiding in sleep. However, individual responses vary, so it’s advisable to observe how your body reacts and consider consulting with a healthcare professional for personalised guidance.

Can hibiscus tea cause bleeding?

While hibiscus tea is generally safe, it contains compounds that may have mild anticoagulant effects. Consuming large amounts could potentially contribute to bleeding issues, so individuals on blood-thinning medications or with bleeding disorders should consult with a healthcare professional before incorporating it into their diet.

How to make hibiscus tea at home?

To make hibiscus tea, take 2 teaspoons of dried hibiscus petals (or 2–3 fresh petals) in 1 cup of hot water for 5–10 minutes. Strain and enjoy warm or chilled.

References

  1. Singh P, Khan M, Hailemariam H. Nutritional and health importance of Hibiscus sabdariffa: a review and indication for research needs. J. Nutr. Health Food Eng. 2017;6(5):00212. Available from: https://www.researchgate.net/profile/Pragya-Singh-24/publication/319999247_Nutritional_and_Health_Importance_of_Hibiscus_Sabdariffa_A_Review_and_Indication_for_Research_Needs/links/59c64a92458515548f326de6/Nutritional-and-Health-Importance-of-Hibiscus-Sabdariffa-A-Review-and-Indication-for-Research-Needs.pdf 
  2. Beverages, tea, hibiscus, brewed [Internet]. FoodData Central. [cited 2022Nov28]. Available from: https://fdc.nal.usda.gov/fdc-app.html#/food-details/171946/nutrients 
  3. Jamrozik D, Borymska W, Kaczmarczyk-Żebrowska I. Hibiscus sabdariffa in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review. Foods. 2022 Jul 19;11(14):2134. Available from: https://www.mdpi.com/2304-8158/11/14/2134/pdf 
  4. McKay DL, Chen CY-O, Saltzman E, Blumberg JB. Hibiscus Sabdariffa L. tea (Tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. Journal of Nutrition. 2009 [cited 2025 May 19]. Available from: https://pubmed.ncbi.nlm.nih.gov/20018807/ 
  5. Sanadheera S, Subasinghe D, Solangaarachchi MN, Suraweera M, Suraweera NY, Tharangika N. Hibiscus rosa-sinensis L.(red Hibiscus) Tea, Can It Be Used as A Home-Remedy to Control Diabetes and Hypercholesterolemia?. Biology, Medicine, & Natural Product Chemistry. 2021 Jul 27;10(1):59-65. Available from: https://www.sciencebiology.org/index.php/BIOMEDICH/article/view/126 
  6. Raduan SZ, Abdul Aziz MW, Roslida AH, Zakaria ZA, Zuraini A, Hakim MN. Anti-inflammatory effects of Hibiscus rosa-sinensis L. and Hibiscus rosa-sinensis var. alba ethanol extracts. International journal of pharmacy and pharmaceutical sciences. 2013;5(4):754-62. Available from: https://ir.unimas.my/11330/1/7844.pdf 
  7. Alarcon-Aguilar FJ, Zamilpa A, Perez-Garcia MD, Almanza-Perez JC, Romero-Nunez E, Campos-Sepulveda EA, Vazquez-Carrillo LI, Roman-Ramos R. Effect of Hibiscus sabdariffa on obesity in MSG mice. Journal of ethnopharmacology. 2007 Oct 8;114(1):66-71. Available from: https://www.sciencedirect.com/science/article/pii/S0378874107003637 
  8. Lin HH, Chan KC, Sheu JY, Hsuan SW, Wang CJ, Chen JH. Hibiscus sabdariffa leaf induces apoptosis of human prostate cancer cells in vitro and in vivo. Food Chemistry. 2012 May 15;132(2):880-91. Available from: https://www.sciencedirect.com/science/article/pii/S0308814611016396 
  1. Hibiscus Sabdariffa: Medlineplus supplements [Internet]. MedlinePlus. U.S. National Library of Medicine; [cited 2022Nov28]. Available from: https://medlineplus.gov/druginfo/natural/211.html 
  2. Alharbi AE, AlHussaini AM, Alshami I. A comprehensive review of the antimicrobial effects of hibiscus species. Cureus. 2024 [cited 2025 May 19]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11619808/ 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh

Introduction

Noni fruit juice is a tropical beverage derived from a fruit called Morinda citrifolia. The noni fruit tree grows in Southeast Asian countries, especially in French Polynesia. Noni fruit is a small-sized edible fruit with a bitter flavour, smells like bad cheese, and appears like a grenade. Although noni fruit juice originated in tropical regions, it has become popular globally. The Burmese used noni fruit to prepare curries; the Australians ate it during the cool-dry seasons. Noni fruit juice was the first whole food approved under the novel food regulations of the European Union in 1997. Noni juice can be prepared both by homemade and commercial methods. The homemade method provides 100% pure noni juice. Today, noni fruit juice is considered a safe, functional food that may enhance the body’s immunity. In addition, Noni fruit juice may be a perfect blend packed with potent antioxidants that may help provide several health benefits1,2.​​ Let us discuss the noni fruit juice benefits, its nutritional value, potential uses, and much more. 

Did you know?

Nutritional Value of Noni Fruit Juice

A 15 ml pure noni fruit juice serving may provide 3.5 kcal of energy3.​​ Nutritional value of Noni Fruit Juice per 15 ml is as follows:

In addition, other bioactive compounds like quercetin, gallic acid, ursolic acid, limonene, xeronine, alizarin, beta-carotene, citifolinoside, scopoletin, damnacanthal, and monoterpene may be present in noni fruit juice. 

Properties of Noni Fruit Juice

Noni Fruit Juice may have the following health-benefitting properties: 

Potential Uses of Noni Fruit Juice

The following are the potential health benefits of noni fruit juice: 

1. For Cancer

Noni fruit juice may have anti-cancer activity. Gastric cancer patients regularly took homemade noni fruit juice, and their condition improved. The effect of cancer reduction may be due to the Noni fruit juice2. However, despite several claims about noni juice being cancer-effective, no human trials exist to back this claim. Therefore, it is essential to consult doctors for cancer treatment and not use it for self-medication.  

2. For Arthritis

Noni fruit juice may have anti-inflammatory properties. In addition, it may help improve joint pain and aid in the flexibility and mobility of the joints. One of the traditional names of noni in the Caribbean was “pain killer.” However, in a clinical trial1, participants were given noni fruit juice. At the end of the trials, the patient’s pain intensity was significantly decreased, with complete relief of neck pain. Hence, noni juice may show certain benefits against arthritis. However, if you experience severe joint pain, consult your doctor and take appropriate treatment. 

3. For Weight Loss

In multiple animal studies1, noni fruit juice has shown significant weight loss with a decrease in body fat. In a clinical study5 by Palu et al. 2011, it was found that when obese adults were given noni fruit juice, every participant experienced weight loss. This may help in managing body fat. However, the study could not determine how much noni juice contributed to weight loss. Hence, more clinical studies are needed to propose a firm conclusion about the uses of noni juice for weight loss. 

4. For Diabetes

The benefits of noni juice may include a lowering of blood sugar levels. In an animal study6 by Umezawa et al., 1992 was found that fermented noni fruit juice may significantly decrease fasting glucose levels. They suggested that noni fruit juice may act as insulin directly or increase peripheral tissue sensitivity to the storage of more insulin. However, this is an animal study; therefore, more human research is needed to suggest the potential uses of noni fruit juice for managing diabetes4.​​ 

5. For Skin Health

Noni juice benefits the skin and may be associated with enhancing skin health. In a clinical trial7, West et al. 2012, found that a noni juice-based skin care regimen in women effectively reduced fine lines, facial wrinkles, and firmness when applied on the face. In addition, there was no report of any skin irritation during or after the trial. Hence, drinking noni fruit juice may help to increase skin health. However, if you have any skin-related issues, consult your doctor and do not self-medicate. 

6. Other Potential Uses of Noni Fruit Juice

Though studies show the potential uses of noni-fruit juice in several conditions, these studies are insufficient, and there is a need for further research to develop the true scope of the benefits of noni-fruit juice on human health. Additionally, it is essential to consult a doctor before using noni fruit juice for any medical condition. 

I would suggest noni juice if you’re looking for a natural way to support your bones and potentially protect your hearing. Noni juice might have some unexpected perks! In a study done among post-menopausal women, those who drank noni juice showed a possible increase in bone resorption (which can help with osteoporosis) and also experienced less hearing loss. Plus, their mental health and overall quality of life improved1.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Noni Fruit Juice

Different types of Noni fruit juice are commercially available based on extraction techniques, such as traditional and non-traditional4. These include: 

You should consult a qualified doctor before using noni fruit juice in large quantities. Do not discontinue or replace an ongoing modern medical treatment with an ayurvedic/herbal preparation of noni fruit juice without consulting an ayurvedic physician. They will guide you with its form and dosage based on your health condition. 

In my opinion, sipping on some noni juice might help you go that extra mile or power through your workout with more energy. Human intervention studies have shown that noni juice may have a surprising benefit—it could boost physical endurance1!

Dr. Smita Barode, B.A.M.S, M.S.

Side Effects of Noni Fruit Juice

Noni juice side effects may include: 

Therefore, it is advised to limit the consumption of noni-fruit juice to avoid such side effects. If such side effects appear, consult your doctor and get proper treatment.

Also Read: Lauki Juice: Uses, Benefits, Side Effects and More!

Precautions to Take with Noni Fruit Juice

Despite the various advantages of noni juice for good health, it is essential to follow certain precautions:  

I recently came across a fascinating study involving heavy smokers and noni juice. After 30 days of consumption, participants who drank noni juice experienced a significant decrease in levels of superoxide anion radicals and lipid hydroperoxide, which are indicators of oxidative stress. This suggests that noni juice may have antioxidant benefits that are good for individuals exposed to tobacco smoke8.

Dr. Rajeev Singh, BAMS

Also Read: 13 Health Benefits of Watermelon and Recipes

Interactions with Other Drugs

More human research and scientific evidence must be conducted to study the possible interaction between noni fruit juice and other drugs. Therefore, people should not assume that there are no interactions at all. Therefore, medical consultations with Ayurvedic doctors are recommended before including noni juice in a diet.

Also Read: Top Health Benefits of Buttermilk

Frequently Asked Questions (FAQs)

Is noni fruit juice suitable for pregnant women? 

No, noni fruit juice is not suitable for pregnant women. It may interfere with foetal development and may create further complications. Therefore, pregnant women should take precautions and avoid having noni juice

What are the side effects of noni fruit juice? 

The noni juice side effects may include nausea, irregular heartbeats, muscle weakness, and hyperkalemia (high amount of potassium in the blood). Therefore, if you observe such side effects, take proper treatment from your doctor. 

What are the vitamins in noni fruit juice? 

Noni fruit juice contains vitamin C, vitamin B3, and vitamin B9.

What are the benefits of noni juice for blood pressure? 

The advantage of noni fruit juice for blood pressure is that it may help to lower systolic high blood pressure. However, consult your doctors if you have a high blood pressure problem, and do not self-medicate. 

Does noni fruit juice interact with other drugs? 

No major report has recorded the interaction of noni juice with other drugs. However, take medical consultations from your doctors and do not use noni juice to self-medicate unless advised.

References

  1. ​​West B, Deng S, Isami F, Uwaya A, Jensen C. The Potential Health Benefits of Noni Juice: A Review of Human Intervention Studies. MDPI | Foods. 2018;7(58):1–22. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920423/pdf/foods-07-00058.pdf 
  2. ​Brown A. Anticancer activity of Morinda citrifolia (Noni) fruit: a review. Phytotherapy research. 2012;26(10):1427–40. Available from: https://pubmed.ncbi.nlm.nih.gov/22344842/ 
  3. ​Chemical Constituents of Pure Noni Juice [Internet]. [cited 2022 Nov 27]. Available from: https://www.ctahr.hawaii.edu/noni/nutritional_analysis_juice.asp 
  4. ​​Ali M, Kenganora M, Santhepete M. Health Benefits of Morinda citrifolia (Noni): A Review. Pharmacognosy Journal. 2016;8(4):321–34. Available from: https://www.phcogj.com/sites/default/files/10.5530pj.2016.4.4.pdf 
  5. Palu AK, West BJ, Jensen J. Noni-based nutritional supplementation and exercise interventions influence body composition. N Am J Med Sci. 2011 Dec;3(12):552–6. doi: 10.4297/najms.2011.3552. PMID: 22363077; PMCID: PMC3271418. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3271418/
  6. Nayak BS, Marshall JR, Isitor G, Adogwa A. Hypoglycemic and hepatoprotective activity of fermented fruit juice of Morinda citrifolia (Noni) in diabetic rats. Evid Based Complement Alternat Med. 2011;2011:875293. doi: 10.1155/2011/875293. Epub 2010 Oct 14. PMID: 20981320; PMCID: PMC2958566. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC2958566/
  7. West BJ, Sabin RA. Efficacy of a Morinda citrifolia based skin care regimen. Curr Res J Biol Sci. 2012;4(3):310–14. Available from: https://www.researchgate.net/publication/267201851_Efficacy_of_a_Morinda_citrifolia_Based_Skin_Care_Regimen#:~:text=Digital%20images%20were%20analyzed%20with,baseline%20of%20both%20the%20semi%2D
  8. Wang MY, Lutfiyya MN, Weidenbacher-Hoper V, Anderson G, Su CX, West BJ. Antioxidant activity of noni juice in heavy smokers. Chem Cent J. 2009 Oct 6;3:13. doi: 10.1186/1752-153X-3-13. PMID: 19807926; PMCID: PMC2765950. Available from: https://pubmed.ncbi.nlm.nih.gov/19807926/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Dark Chocolate: Uses, Benefits, Side Effects By Dr. Smita Barode

Introduction

Chocolates are the most commonly available food item; everyone likes them and desires to eat them. It is hard to find a single person who does not like chocolates. Dark chocolates are semisweet, with extra dark having a sweet and bitter taste. It is prepared from cocoa seeds. It is also called black chocolate and is prepared by adding fat and sugar to the roasted and ground cocoa with less milk. It has the highest percentage of cocoa, about 70% to 99%. Chocolate originated in Mexico. Where the Mayans and Aztecs cultivated the cacao tree, which is native to the American tropical rainforest. Due to its health benefits, chocolate drinks were considered “the drink of Gods.” The scientific name of the cocoa tree is Theobroma cacao1,3.​ Let us discuss the health benefits of dark chocolate, its nutritional value, potential uses, and many more.  

Nutritional Value of Dark Chocolate

One hundred grams of dark chocolate may have 598 kcal energy4​. The nutrients of dark chocolate include: 

Nutritional value of Dark Chocolate per 100 grams4.

Furthermore, other biologically active compounds like theobromine, phenylethylamine, N-acyl ethanolamines, tyramine, epicatechin, catechin, procyanidins, alkaloids, polyphenols, and theophylline may be present in it1,2

When it comes to dark chocolate, remember that a little goes a long way. While it offers enticing flavours and potential health benefits, it’s important to be mindful of its calorie content. Dark chocolate can be quite calorie-dense, with around 150-170 calories per ounce8.

Dr. Siddharth Gupta, B.A.M.S M.D (Ayu)

Properties of Dark Chocolate

The benefits of eating dark chocolate may include the following properties: 

Regular consumption of dark chocolates might reduce inflammation by reducing the levels of C-reactive protein in the body. Additionally, the anti-inflammatory action of dark chocolates is due to the antioxidants and flavonoids in them10.

Dr. Anuja Bodhare, B.A.M.S M.D (Ayu)

Potential Uses of Dark Chocolate

Dark chocolate may be ideal for enhancing human health2. The following may be the potential uses of eating dark chocolate: 

1. Potential Uses of Dark Chocolate for Cancer

Dark chocolate contains antioxidants like flavonoids and cocoa-derived pentameric procyanidin, which might act against free radicals. These free radicals cause oxidative cell damage and may also lead to cancer. A study5 by Keen CL et al., 2005 suggested that eating dark chocolate may help defend the body from various types of cancer and slow down the signs of ageing. However, new studies are needed to suggest the potential uses of dark chocolate for fighting cancer. Cancer is a serious health condition. Therefore, proper diagnosis and treatment are needed, and do not self-medicate. 

2. Potential Uses of Dark Chocolate for Oral Health

Dark chocolate has a theobromine compound, which might help harden the tooth enamel. It may help maintain proper dental hygiene and lower the risk of dental cavities. In addition, theobromine may suppress the function of the vagus nerve (a nerve that causes coughing) and may help reduce coughs1,2. However, if you have oral health issues, visit your dentist and get a proper check-up. 

3. Potential Uses of Dark Chocolate for Diabetes

Dark chocolate contains magnesium and flavonoids that may potentially function against Type-2 diabetes. A study6 by Grassi D et al., 2005, suggests that it contains flavonoids which may help reduce insulin resistance. Flavonoids may help the cells work normally and restore the ability to use the body’s insulin. Dark chocolate may also have a low glycaemic index and may not cause huge spikes in blood sugar levels2. However, more human studies are required to suggest that dark chocolate acts against diabetes. Diabetes is a serious disease, and it is essential to have a doctor’s consultation.  

4. Potential Uses of Dark Chocolate for Blood Pressure

Dark chocolate may have an antioxidant capacity. Additionally, it contains an epicatechin compound, which may help lower blood pressure and enhance endothelial functions. A study7 by Lakshmana Rao et al., 2014, suggested that epicatechin may reduce high blood pressure and end-organ damage in animal models. Furthermore, dark chocolate also contains flavanol, which might release nitric oxide and plays a key role in high blood pressure1. However, more human research is needed to suggest the use of dark chocolate against high blood pressure. Therefore, take the doctor’s advice and do not use dark chocolate to self-medicate. 

5. Potential Uses of Dark Chocolate for Heart

The advantages of dark chocolate may be associated with reducing heart disorders. It contains minerals such as copper and potassium, which may help against stroke. Dark chocolate also has flavanols that may reduce the chances of atherosclerosis (hardening of arteries). Additionally, it may help the flexibility of arteries and reduce the white blood cells from sticking to the blood vessels2. However, there is a requirement for further studies to conclude the use of dark chocolate for heart diseases. If you have any issues related to the heart, consult your doctor and do not self-medicate. 

6. Potential Uses of Dark Chocolate for Brain

Various data analyses have reported that eating dark chocolate may benefit blood flow to the brain and heart, enhancing cognitive (brain) functions. In addition, its chemical components, which have stimulant activity, may positively affect our mood and brain health. For example, dark chocolate may contain phenylethylamine, which may help release endorphins and increase alertness. It also contains caffeine, a mild stimulant, and may help with mood disorders 1,2. We need more research to develop its uses for human health. Suppose you have any problems related to the brain; consult your doctor and do not self-medicate. 

7. Other Potential Uses of Dark Chocolate

Though studies show the potential uses of dark chocolate in various conditions, these are insufficient, and there is a necessity for further studies to develop the scope of the benefits of dark chocolate on human health.  

When it comes to chocolate, opt for the dark side! Dark chocolate contains significantly higher amounts of flavanol-rich cocoa solids compared to milk chocolate, packing a powerful punch of health benefits. These flavanols work their magic by supporting the production of nitric oxide in the inner lining of our blood vessels, called the endothelium8.

Dr. Rajeev Singh, BAMS

How to Use Dark Chocolate?

Dark chocolate is in the form of liquid, paste, or block1,2. You may use dark chocolate as 

You should consult a qualified doctor before eating dark chocolate in large quantities. Do not discontinue or replace an ongoing modern medical treatment with an Ayurvedic/herbal preparation of dark chocolate without consulting an Ayurvedic physician. They will guide you with their form and dosage based on your health condition. 

When it comes to dark chocolate, aim for a minimum of 70% cocoa content or higher to maximize your intake of beneficial flavanols. These flavanols are key players in providing potential health advantages. However, do keep in mind that as the cocoa percentage increases, the flavour tends to become more bitter8.

Dr. Ashok Pal, BAMS

Side Effects of Dark Chocolate

There are many advantages of dark chocolate. It may also cause caffeine-related side effects. However, below are a few dark chocolate side effects: 

You must consult your doctors to get the proper treatment if you encounter such side effects. 

Here’s a delightful secret to safeguarding your skin from the sun’s harmful rays: dark chocolate! The antioxidants found in dark chocolate, known as flavonols, come to the rescue by boosting blood flow to your skin and acting as a protective shield against damaging ultraviolet (UV) radiation9.

Dr. Smita Barode, B.A.M.S M.S.

Precautions to Take with Dark Chocolate

Eating dark chocolate in small quantities might be safe. However, eating in larger amounts may be harmful. Therefore, a few precautions are necessary:  

Also Read: Corn Flour: Uses, Benefits, Side Effects By Dr. Rajeev Singh

Interactions with Other Drugs

It may interfere with certain drugs/medicines, leading to drug interaction3​. 

Therefore, you should avoid eating dark chocolate with any medicine, and if any complications arise, consult with doctors.  

Frequently Asked Questions (FAQs)

What is dark chocolate? 

Dark chocolate is a sweet, extra-dark food item with a bittersweet taste. Dark chocolate is made from Theobroma cacao seeds by adding cocoa butter (fat) and sugar to the roasted and ground cocoa with less or no milk1,2.

What are the disadvantages of dark chocolate for pregnant women? 

Dark chocolate contains caffeine which may affect pregnant women and the baby in the womb. Therefore, pregnant women are not recommended to have dark chocolate3.

What are the side effects of eating dark chocolate? 

The dark chocolate side effects may be associated with caffeine. It may cause sleeplessness, nervousness, increased urination, fast heartbeat, skin allergies, migraine and headache, nausea, and stomach problems like gas and constipation3.

What are the vitamins of dark chocolate? 

Dark chocolate vitamins may include vitamins like A, K, E, B12, B6, B5, B3, B2 and B4.

What is the percentage of cocoa present in dark chocolate? 

Dark chocolate contains around 70-99% pure cocoa solids, butter, and sugar1.

References

​​1. “Dark chocolate: An overview of its biological activity, processing, and fortification approaches.” Current Research in Food Science. 2022 Oct 15;5:1916-1943. PMCID: PMC9589144. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9589144/

​2. Patel N, Jayswal S, Maitreya B, Nirali Patel. Dark chocolate: Consumption for human health. Journal of Pharmacognosy and Phytochemistry. 2019;8(3):2887–90. Available from: https://www.phytojournal.com/archives/2019/vol8issue3/PartAO/8-2-565-157.pdf 

​3. Arakelyan H. Chocolate and Drugs Dangerous Interactions [Internet]. 2014 [cited 2022 Nov 26]. Available from: https://www.researchgate.net/publication/275584061_Chocolate_and_Drugs_Dangerous_Interactions 

​4. FoodData Central | Chocolate, dark, 70-85% cacao solids [Internet]. U.S. DEPARTMENT OF AGRICULTURE. 2019 [cited 2022 Nov 26]. Available from: https://fdc.nal.usda.gov/fdc-app.html#/food-details/170273/nutrients 

5. Keen CL, Holt RR, Oteiza PI, Zeng H, Wang H, Gruber HE, et al. Cocoa antioxidants and cardiovascular health. Physiol Behav. 2006 Jul;88(3):189-97. PMID: 15640494. Available from: https://pubmed.ncbi.nlm.nih.gov/15640494/

6. Grassi D, Lippi C, Necozione S, Desideri G, Ferri C. Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons. Am J Clin Nutr. 2005 Mar;81(3):611-4. doi:10.1093/ajcn/81.3.611. Available from: https://pubmed.ncbi.nlm.nih.gov/15755830/

7. Haritha K, Kalyani L, Lakshmana Rao A. Health Benefits of Dark Chocolate. J Adv Drug Deliv. 2014;1(4):184-95. Available from: https://www.scribd.com/document/733636778/1

8. Harvard T.H. Chan School of Public Health. Dark Chocolate [Internet]. The Nutrition Source; [cited 2025 Sep 18]. Available from: https://nutritionsource.hsph.harvard.edu/food-features/dark-chocolate/

9. Cleveland Clinic. Is dark chocolate good for you? 6 benefits [Internet]. Cleveland: Cleveland Clinic; 2025 Jul 30 [cited 2025 Sep 20]. Available from: https://health.clevelandclinic.org/dark-chocolate-health-benefits

10. Di Giuseppe R, Di Castelnuovo A, Centritto F, Zito F, De Curtis A, Costanzo S, Vohnout B, Sieri S, Krogh V, Donati MB, de Gaetano G, Iacoviello L. Regular consumption of dark chocolate is associated with low serum concentrations of C-reactive protein in a healthy Italian population. J Nutr. 2008 Oct;138(10):1939-45. PMID: 18806104. Available from: https://pubmed.ncbi.nlm.nih.gov/18806104/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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