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Phalsa fruit (Grewia asiatica): Uses, Benefits, and Side Effects By Dr. Smita Barode 

Introduction

“With the changing times, not only the country’s policymakers but the whole world is realising the importance of Ayurveda. Who would’ve thought that people in the upcoming generations would prefer a bottle of gooseberry or bottle gourd juices over carbonated drinks?” Despite this realization of the health benefits of plants and fruits, there are fruits like Phalsa which, although are high in nutrients but low in popularity. Phalsa is a plant that originates in Southeast Asian countries like India, Nepal, Sri Lanka and Bangladesh and is mainly grown for its fruit. The scientific name of the Phalsa fruit is Grewia asiatica, also known as the Indian Sherbet berry. It is a seasonal plant and the fruits are generally obtained in the summer. Phalsa fruit resembles grapes in its shape and size. They are purple in colour with a sour-sweet taste. The fruit is a powerhouse of vitamins and minerals and offers many health benefits; let us know more about those benefits1

Nutritional Value of Phalsa Fruit

Phalsa fruit is rich in carbohydrates, fibres, proteins, vitamins A, B3 and C and minerals like potassium, calcium, iron and phosphorus. The phytochemicals present in Phalsa fruit include anthocyanins, tannins, phenols and flavonoids. The nutritional chart of this fruit is given below.  

Properties of Phalsa Fruit

Phalsa fruit shows numerous scientifically proven properties; some of which are mentioned below1

I’ve discovered that Phalsa fruits have a cooling effect on the body. Phalsa fruit is rich in phenols. This property makes it a potential natural remedy for excessive body heat9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Phalsa Fruit for Overall Health

Some of the potential benefits of Phalsa fruit are described below. 

1. Potential Use of Phalsa Fruit in Diabetes

diabetes

Diabetes (Type I & II) is characterised by an increase in blood glucose due to a reduction or resistance to insulin (a hormone that regulates blood glucose). Literature shows that fruits rich in polyphenols may positively impact diabetes. Parveen et al. conducted a study2 on diabetic rabbits in 2013 to assess the effect of Phalsa fruit on blood glucose. This study showed a reduction in rabbits’ blood glucose after administering Phalsa fruit. Additionally, this fruit has a low glycemic index and the presence of polyphenols may help reduce blood glucose levels. This indicates that Phalsa fruit may help manage diabetes. However, to claim these results in humans, we need more studies. It is further advised not to self-medicate and consult your physician for proper management of diabetes3

2. Potential Uses of Phalsa Fruit in Dyslipidemia

cholesterol

Dyslipidemia is characterised by an increase in total cholesterol and triglycerides. Studies have shown that Phalsa fruit may potentially control the altered parameters in dyslipidemia. An animal study4 conducted by Parveen et al. in 2013 showed a positive relationship between the consumption of this fruit and lipid levels. Rabbits administered Phalsa fruit extract (200mg/kg) showed reduced total cholesterol and triglycerides. This may indicate that this fruit’s consumption may help manage dyslipidemia. However, more studies on humans are needed to support these claims. Additionally, it is advised not to rely on Phalsa fruit as a remedy for managing dyslipidemia and kindly consult your physician for the proper management of dyslipidemia. 

3. Potential Uses of Phalsa Fruit in Breast Cancer

breast cancer

Breast cancer is one of the most common cancers affecting women worldwide; different ayurvedic treatments are being tested for their effectiveness towards breast cancer. A review2 by Muhammed et al. in 2013 states that Phalsa fruit contains smart molecules called anthocyanins which help reduce the multiplication of abnormal cells and the risk of cancers. Thus, it may be concluded that Phalsa fruit may reduce breast cancer risk. However, we need more human studies to claim these results accurately. Also, it is advised not to consider Phalsa fruit as an alternative to modern medicine; you should always consult your doctor for proper management of breast cancer. 

4. Potential Uses of Phalsa Fruit as an Antibacterial Agent

phalsa fruit

Traditionally, herbs, spices, leaves and fruits obtained from plants were used for managing bacterial infections. Muhammed et al. conducted a review2 in 2013 to test the efficacy of Phalsa fruit on different bacteria. The presence of polyphenols in Phalsa fruit inhibited the growth of S.typhi bacteria; thus, it may have the potential to manage bacterial infections like Typhoid caused by S.typhi bacteria. However, we need more studies to confirm these results in humans. Additionally, you should not consider Phalsa fruit as a remedy for managing Typhoid; it is always advised to consult a physician for proper management of Typhoid. 

5. Potential Uses of Phalsa Fruit in Depression

stress

Depression is a mood disorder that results in sadness and loss of interest and may affect everyday activities. Previous studies have shown that healthy nutrition may help in managing various ailments. A study4 conducted by Imran et al. in 2021 stated that Phalsa fruit, due to the presence of antioxidants like phenols, anthocyanins, flavonoids, etc., may help in managing depression. Additionally, this fruit can potentially reduce anxiety (anxiolytic effect). Therefore, Phalsa fruit may have the potential to manage depression. To claim these results for humans, we need more studies. It is further advised not to consider Phalsa fruit as an alternative to modern medicine; kindly consider your doctor for proper management of depression5

6. Other Potential Uses of Phalsa Fruit

digestion problems

Though there are studies that show the benefits of Phalsa fruit in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of Phalsa fruit on human health.  

Let me give you a tip! Phalsa fruit might take care of your skin. Phalsa fruit is rich in antioxidants and numerous vitamins and minerals, which makes Phalsa a potential contributor to achieving flawless skin10.

Dr. Rajeev Singh, BAMS

How to Use Phalsa Fruit?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Phalsa Fruit

Phalsa fruit is considered safe when eaten in minimal amounts. A few side effects related to the consumption of Phalsa fruit include: 

However, if you experience any adverse reactions to Phalsa fruit, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Also Read: Mango (Aam): Uses, Benefits, Side Effects by Dr. Smita Barode

Precautions to Take with Phalsa Fruit

Consuming Phalsa fruit is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions1

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Phalsa fruit with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking. 

Also Read: 10 Health Benefits And Recipes Of Dragon Fruit (Pitaya)

Frequently Asked Questions (FAQs)

What does Phalsa fruit look like? 

Phalsa fruit resembles grapes in its shape and size. They are purple in colour and sour to sweet in taste1.

What is the scientific name of Phalsa fruit? 

Phalsa fruit is called Grewia asiatica1. 

What is Phalsa fruit in Hindi? 

In Hindi, Phalsa fruit is called Sherbet berry.

Does the Phalsa fruit benefits weight loss? 

No, there are no proven results on the efficacy of the Phalsa fruit for reducing weight.

Is it okay to eat Phalsa fruit during pregnancy? 

The safety of Phalsa fruit consumption in pregnancy is not well-established; it is therefore advised to consult your doctor if you plan to add Phalsa fruit to your diet. 

References

  1. Mehmood, Arshad et al. “Nutraceutical perspectives and value addition of phalsa (Grewia asiatica L.): A review.” Journal of food biochemistry vol. 44,7 (2020): e13228. doi:10.1111/jfbc.13228. available at: https://pubmed.ncbi.nlm.nih.gov/32320069/ 
  2. Muhammad et al. “Grewia asiatica L., a food plant with multiple uses.” Molecules (Basel, Switzerland) vol. 18,3 2663-82. 28 Feb. 2013, doi:10.3390/molecules18032663. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270019/ 
  3. Khattab, Hala A H et al. “Antihyperglycemic Potential of Grewia asiatica Fruit Extract against Streptozotocin-Induced Hyperglycemia in Rats: Anti-Inflammatory and Antioxidant Mechanisms.” Oxidative medicine and cellular longevity vol. 2015 (2015): 549743. doi:10.1155/2015/549743. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542021/ 
  4. Imran et al. “Grewia asiatica Berry Juice Diminishes Anxiety, Depression and Scopolamine-Induced Learning and Memory Impairment in Behavioral Experimental Animal Models.” Frontiers in nutrition vol. 7 587367. 15 Jan. 2021, doi:10.3389/fnut.2020.587367. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844311/ 
  5. Chand, Suma P. and Hasan Arif. “Depression.” StatPearls, StatPearls Publishing, 18 July 2022. Available at: https://pubmed.ncbi.nlm.nih.gov/28613597/ 
  6. Khan, Rao & Asghar, Waqas & Khalid, Nauman & Nazir, Wahab & Farooq, Muhammad & Ahmed, Iftikhar & Syed, Qamar Abbas. (2019). Phalsa (Grewia asiatica L) fruit berry a promising functional food ingredient: A comprehensive review. Journal of Berry Research. 9. 10.3233/JBR-180332. Available at: https://www.researchgate.net/publication/329936198_Phalsa_Grewia_asiatica_L_fruit_berry_a_promising_functional_food_ingredient_A_comprehensive_review 
  7. Chung, K T et al. “Tannins and human health: a review.” Critical reviews in food science and nutrition vol. 38,6 (1998): 421-64. doi:10.1080/10408699891274273. Available at: https://pubmed.ncbi.nlm.nih.gov/9759559/ 
  8. Skibola, C F and M T Smith. “Potential health impacts of excessive flavonoid intake.” Free radical biology & medicine vol. 29,3-4 (2000): 375-83. doi:10.1016/s0891-5849(00)00304-x. Available at: https://pubmed.ncbi.nlm.nih.gov/11035267/ 
  9. Sivakumar D, Sultanbawa Y, Netzel M, editors. Handbook of Phytonutrients in Indigenous Fruits and Vegetables. CABI; 2022. P. 390. Available from: https://books.google.co.in/books?hl=en&lr=&id=vFacEAAAQBAJ&oi=fnd&pg=PA390&dq=phalsa+fruit+medicinal+uses&ots=rVQOJWvYfP&sig=Vz0jO1LIB6RpAMcHA-VCfL6a-eY&redir_esc=y#v=onepage&q=phalsa%20fruit%20medicinal%20uses&f=false
  10. Hassan H, Amin M, Rajwana IA, Ullah S, Razzaq K, Faried HN, et al. Nutritional functions and antioxidative enzymes in juice extract from two different maturity stages of low temperature stored phalsa (Grewia subinaequalis D.C.) fruit. LWT – Food Science and Technology. 2022;153:112552. Available from: https://www.sciencedirect.com/science/article/pii/S0023643821017059

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Madhunashini (Gymnema Sylvestre): Uses, Benefits and Side Effects By Dr. Smita Barode

Introduction

“Ayurveda, a most sacred science of life, is beneficial to humans both in this world and the world beyond”. Ayurveda focuses on improving human health and well-being through herbs and spices. One such herb which is of great significance is Madhunashini. Madhunashini is also known as meshashringi (Sanskrit), gurmar and merasingi (Hindi), vakundi, kavuli and kalikardori (Marathi), dhuleti and mardashingi (Gujarathi), Podapatri (Telugu) and Cherukurinja (Tamil). The scientific or botanical name of Madhunashini is Gymnema sylvestre and it belongs to the Asclepiadaceae family. It is a medicinal woody climber native to western and Central India, Australia, and tropical Africa. In India, it is widely grown in Bihar, Chhattisgarh Andhra Pradesh, Kerala, Karnataka, Uttar Pradesh, Madhya Pradesh, and West Bengal. The leaves, flowers, and root extracts have medicinal properties. Let us know more about the health benefits of this wonder plant1,2.

Nutritional Value of Madhunashini

Madhunashini has nutrients like carbohydrates, proteins, and other phytochemical constituents like saponins, sterols, terpenoids, glycosides, alkaloids, resins, etc3.

Did you know?

  • A study showed that Madhunashini extract improved insulin sensitivity in patients with type 2 diabetes. source: ncbi
  • Research suggests that Madhunashini may help reduce the risk of diabetic complications such as neuropathy and nephropathy. source: diabetesjournals.org

Properties of Madhunashini

Scientifically proven properties of Madhunashini include1:

Based on my experience, I have found that the leaf extract of madhunashini might have antiarthritic effects. The extract contains certain compounds that could potentially inhibit inflammation and reduce the release of pain-causing substances, which may help in managing arthritic symptoms8.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Madhunashini for Overall Health

Some of the potential benefits of Madhunashini are described as under:  

1. Potential Uses of Madhunashini in Diabetes

Home Remedies For Diabetes
Image Source: freepik.com

We can’t deny that diabetes is one of the most common diseases, showing an increasing trend worldwide. Even in their 20s, youngsters have complaints of high blood glucose levels because of unhealthy dietary choices and a sedentary lifestyle. A review1 by Kanetkar et al. in 2007 stated that Madhunashini exerts anti-diabetic effects due to the presence of gymnemic acids. The possible mechanism attributed is an increase in insulin secretion, a hormone that regulates blood glucose. Additionally, gymnemic acids help inhibit glucose absorption from the intestine and increase glucose utilization. This indicates that Madhunashini may help manage diabetes. However, more studies are needed to support these claims with greater reliability1.

2. Potential Uses of Madhunashini for Lipid Profile

Cholesterol normal range
Image Source: freepik.com

A lipid profile is a blood test that measures the number of triglycerides and cholesterol in the blood. An altered lipid profile is a risk factor for diseases like atherosclerosis, pancreatitis, etc. Eisenberg et al. 2003 conducted a study8 in rats. This study showed that Madhunashini leaf extracts could reduce serum triglycerides, low-density lipoprotein, total cholesterol, etc. This indicates that Madhunashini has the potential to correct an abnormal lipid profile. However, these results are based on animal studies and more studies are needed to claim these effects in humans4.

3. Potential Uses of Madhunashini in Obesity

Image Source: freepik.com

Obesity is a complex disease characterized by excess body fat, which can negatively affect health. Studies have supported the fact that using food sources in the right quantity and the use of complementary and alternative medicine like yoga and ayurvedic herbs may help in weight loss. A review4 conducted by Fabio et al. in 2013 stated that Madhunashini has the potential to manage obesity. This effect is attributed to inhibiting taste perception by gymnemic acids present in Madhunashini leaf and root extracts which may limit your food intake. This indicates that the Madhunashini may aid weight loss by decreasing the intake of calories. However, we need more studies to support these claims with greater reliability4,5

4. Potential Uses of Madhunashini in Cancer

cancer
Image Source: freepik.com

Cancer is a disease in which cells of the body may multiply abnormally and form cancerous cells that may spread to other parts of the body. A review4 conducted by Fabio et al. in 2013 states that Madhunashini may help manage breast and lung cancer. The exact mechanism behind this effect is, however, still being determined. This indicates that Madhunashini may help with cancer. However, scientific evidence supporting these claims is limited. Therefore, we need more studies to support these claims4.

5. Potential Uses of Madhunashini as an Antibacterial Agent

infection
Image Source: freepik.com

Many antibacterial agents in Ayurveda have been used for managing bacterial infections; one such agent is Madhunashini. A review4 conducted by Fabio et al. in 2013 stated that Madhunashini leaf extract might have antibacterial activity against bacteria like E.coli and Salmonella species. By killing these bacteria, Madhunashini may help manage urinary tract infections, diarrhoea, typhoid, etc. This indicates that it may help manage a wide range of bacterial infections. Additionally, it may also help in managing dental caries, usually caused by bacteria, and thus may help improve dental hygiene. However, there is no scientific study done on humans to support these claims4.

6. Other Potential Uses of Madhunashini

constipation
Image Source: freepik.com

Though there are studies that show the benefits of Madhunashini in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of Madhunashini on human health.  

In my experience, madhunashini extract may have potential benefits in wound healing. The extract contains flavonoids, which are known for their antioxidant properties. While further studies are needed, incorporating its extract in wound care may support the healing process8.

Dr. Rajeev Singh, BAMS

How to Use Madhunashini?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Did you know that the root bark of Madhunashini has been historically used as an emetic, expectorant, and analgesic for body aches? It has also been utilized as a traditional remedy for snakebites, with the root juice playing a role in its treatment8.

Dr. Smita Barode, B.A.M.S, M.S.

Side Effects of Madhunashini

However, if you experience any adverse reactions to Madhunashini, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Also Read: Gokshuradi Guggulu: Uses, Benefits, Side Effects and more!

Precautions to Take with Madhunashini

Consuming Madhunashini is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions7

Also Read: Vasaka (Malabar Nut): Uses, Benefits and Side Effects by Dr. Rajeev Singh 

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Madhunashini with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking7.

Also Read: Triphala: Uses, Benefits, Side Effects & More!

Frequently Asked Questions (FAQs)

What is Madhunashini also known as? 

Madhunashini is also known as meshashringi (Sanskrit), gurmar and merasingi (Hindi), vakundi, kavuli and kalikardori (Marathi), dhuleti and mardashingi (Gujarathi), Podapatri (Telugu) and Cherukurinja (Tamil)1.

What is the scientific name of the Madhunashini plant? 

The scientific name of the Madhunashini plant is Gymnema sylvestre, which belongs to the Asclepiadaceae family1.

Does Madhunashini interact with food?  

No, there are no interactions of Madhunashini with food7.

Is Madhunashini available in the market? 

Yes, it is available in the market as Madhunashini tablet, capsules, extract, powder, paste, etc6.

What is Madhunashini called in Tamil? 

Madhunashini in Tamil is known as Cherukurinja1.

References

  1.  Kanetkar, Parijat et al. “Gymnema sylvestre: A Memoir.” Journal of Clinical Biochemistry and Nutrition vol. 41,2 (2007): 77-81. doi:10.3164/jcbn.2007010. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170951/
  1. Pandey, Ashok Kumar and Swati Yadav. “Variation in gymnemic acid content and non-destructive harvesting of Gymnema sylvestre (Gudmar).” Pharmacognosy research vol. 2,5 (2010): 309-12. doi:10.4103/0974-8490.72330. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093035/ 
  1. Khan, Farzana et al. “Comprehensive Review on Phytochemicals, Pharmacological and Clinical Potentials of Gymnema sylvestre.” Frontiers in pharmacology vol. 10 1223. 29 Oct. 2019, doi:10.3389/fphar.2019.01223. Available at: https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2019.01223/full
  1. Di Fabio G, Romanucci V, Zarrelli M, Giordano M, Zarrelli A. C-4 Gem-Dimethylated Oleanesof Gymnema sylvestre and Their Pharmacological Activities. Molecules. 2013; 18(12):14892-14919. Available at: https://www.mdpi.com/1420-3049/18/12/14892 
  1. Lin, Xihua and Hong Li. “Obesity: Epidemiology, Pathophysiology and Therapeutics.” Frontiers in endocrinology vol. 12 706978. 6 Sep. 2021, doi:10.3389/fendo.2021.706978. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450866/ 
  1. Saneja A, Sharma C. Gymnema sylvestre (Gurmar): a review. Der Pharmacia lettre [Internet]. 2010;2(1):275–84. Available from: https://www.scholarsresearchlibrary.com/articles/gymnema-sylvestre-gurmar-a-review.pdf 
  1. Medlineplus. Gymnema [Internet]. Vol. 2, MedlinePlus National Library of Medicine. 2021. Available from: https://medlineplus.gov/druginfo/natural/841.html 
  2. Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of *Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014;2014:830285. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3912882/
  3. Preuss, H. G., Jarrell, S. T., Scheckenbach, R., Lieberman, S., & Anderson, R. A. (1998). Comparative effects of chromium, vanadium and Gymnema sylvestre on sugar-induced blood pressure elevations in SHR. Journal of the American College of Nutrition, 17(2), 116–123. doi:10.1080/07315724.1998.10718736. PMID: 9550454. Available from: https://pubmed.ncbi.nlm.nih.gov/9550454/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Kutki: Uses, Benefits and Side Effects by Dr. Rajeev Singh  

Introduction

With rising health awareness, people around the world are exploring foods with wonderful nutrients and health benefits. A millet that has gained popularity recently is Kutki. It is scientifically known as Picrorhiza kurroa Royle ex. Benth. It belongs to the family Plantaginaceae. It is mainly grown at 3000-5000 m. above sea level in the Himalayan region of India, Nepal, Pakistan, western China, Tibet and Burma1

Kutki is a small annual herb with a long root, creeping stems and oval leaves. The plant is harvested from October to December1. It is known by different names in different languages and regions. Kutki in English is called hellebore, kutki in Hindi is called as tikta, kaurohini, kavi, tiktarohini, kauka, sutiktaka, and rohini, kutki in Tamil is katuka rohini, kadugurohini, and katuku rohini whereas kutki in Malayalam is katuka rohini and kaduk rohini2. 

In our article, we have described the roots of kutki. These are bitter to taste and their extract is used for medicinal purposes. Kutki herb benefits are recorded in the Ayurveda Samhitas1. Keep scrolling down to read about the kutki benefits and side effects! 

Friendly Reminder: The information shared here is for educational purposes only and the reader should consult a registered medical practitioner before implementing any changes to their health routine.

Did you know?

Nutritional Value of Kutki

Kutki has many phytochemicals. A few of the chemical constituents of kutki are as follows1

Although more research is required to understand the nutritional value of kutki, according to B & B organics, the nutritional value of kutki is as follows: 

According to my experience, to get maximum health benefits from Kutki, you must take them in certain dosages. For example, for fatty liver, you must take Kutki root powder (2 to 3 gms) with warm water two times every day, at least for three months to see the effects. However, you must avoid self-medication and always opt for medical advice before its use5.

Dr. Siddharth Gupta, B.A.M.S M.D (Ayu)

Properties of Kutki

Kutki might have the following properties1:  

Potential Uses of Kutki for Overall Health

The existing studies show the following kutki health benefits:  

1. Potential uses of kutki for diabetes

regulates blood sugar

Blood sugar levels in diabetes are high that cause damage to the eyes, bones, heart and other organs. A study2 by Joy et al. in 1999 on rats showed that extracts from kutki can lower blood sugar levels. It also showed that it could reduce the damage caused by a chemical called alloxan in diabetes, which may prevent further complications of diabetes. The study proves that kutki extracts might be helpful for people with diabetes. However, before taking it, you should consult a doctor and understand the benefits of kutki powder for diabetes.   

2. Potential use of kutki for obesity

reduce belly fat

Obesity is an inflammatory and metabolic disorder that occurs due to excess accumulation of fat in the body tissue that releases various inflammatory mediators that can cause cellular damage. A study1 by Almeleebia et al. in 2022 showed that the root extracts of kutki can reduce the levels of inflammatory mediators involved in inflammatory processes. Therefore, kutki might help with inflammation and inflammatory diseases, but you should always consult a doctor regarding kutki benefits.  

3. Potential uses of kutki for microbial infections

skin itchiness

Bacteria and fungi can enter the body and release toxins that can cause infection in the eyes, nose, skin, lungs and other body organs. A study1 by Almeleebia et al. in 2022 showed that the phytochemicals found in the kutki extracts could inhibit the growth of bacteria and fungi in the body and may help in managing bacterial and fungal infections. However, it is advised not to self-medicate. You should consult the doctor regarding kutki powder benefits and seek treatment accordingly. 

4. Potential uses of kutki in cancer

Cancer is the second leading cause of death worldwide. A study3 by Rajkumar et al. in 2011 found that kutki extracts are rich in flavonoids, phenolic acids, and antioxidants that can stimulate the cell death process in cancerous cells of the breast, liver, and prostate cancer. The study shows that kutki might help in slowing the progression of cancer. However, if you suspect cancer, do not self-medicate. Consult your doctor regarding the benefits of kutki and seek treatment accordingly.  

5. Potential uses of kutki for liver diseases

liver health

The liver is a major organ that plays a vital role in the absorption of fat, synthesis of hormones and detoxification of the body. A study1 by Almeleebia et al. in 2022 showed that kutki benefits in liver-related issues such as jaundice, recurrent fever and viral hepatitis. Its extracts have kutkin, which protects the liver by suppressing substances that can harm liver health. The phytochemicals in kutki extracts also help in reducing the liver toxicity caused by alcohol. Although more research is required to understand the benefits of kutki for liver cirrhosis, the study shows that kutki might help manage liver diseases. However, you should not self-medicate with it and consult the doctor regarding kutki benefits for the liver.  

6. Potential uses of kutki for stomach ulcers

digestion problems

When stomach or intestinal linings get damaged because of the acid present, it causes stomach or intestinal ulcers. A study1 by Almeleebia et al. in 2022 showed that kutki root extracts have a protective effect on the stomach. It can reduce ulcers caused by a medicine named Indomethacin. The extract promotes mucus formation, which protects the stomach and intestinal lining from ulcer formation. It also lowers the production of chemicals involved in ulcer formation. The study shows that kutki might help those struggling with ulcers1. However, you should consult with a doctor instead of self-medicating.  

Other potential uses of kutki

heart

Let’s see some more kutki medicinal uses1

Although with the advancement in knowledge and technology, new research methods are employed to study the health benefits of kutki, they still need to be improved, and further studies are required.   

I would suggest following the dosage of Kutki powder for its benefits for fever, high cholesterol, gastritis, and hepatitis. For fever, you must boil two gms of Kutki powder in 100 ml of water till it reduces to 1/4th of its initial quantity. Similarly, two gms of Katuki powder mixed with sugar after a meal two times a day can be beneficial in gastritis. For high cholesterol and hepatitis, Kutki powder should be mixed with Haridra powder and Bhumya Malaki, respectively.

Dr. Rajeev Singh, BAMS

How to Use Kutki?

Kutki can be used in the following ways:  

 
You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.     

Side Effects of Kutki

Consuming kutki formulations in healthy amounts is considered safe. However, a study by Almeleebia et al. in 2022 showed that the highest safe dose of kutki in a day is 2000mg/kg, any dose above it may have noticeable side effects.  

Although there are insufficient studies on humans to study the kutki powder side effects, it is best to consult a doctor if you notice any unusual symptoms.   

Precautions to Take with Kutki

A few of the important precautions that should be taken when using kutki are as follows:    

The important contraindications where the use of Kutki is not advised: 

Also Read: 8 Effective Herbs To Lower Blood Sugar Levels!

Interactions with Other Drugs

There is not enough evidence on the interaction of the kutki extracts with other drugs. Further studies are required. Therefore, you must consult your doctor before consuming kutki along with your prescribed medication.

Also Read: Ashoka Tree: Uses, Benefits, Side Effects and More!  

Frequently Asked Questions (FAQs)

What are the health benefits of kutki? 

Kutki churna benefits in constipation, skin problems, jaundice, heart problem, allergy, digestion, obesity, and breathing problems.

What are the other names of kutki?  

Kutki is also known as katuka, Katuki, Kuru, Kurri, Katuko, Katukarogani, Kadu, Kutka, HuHuang Lian, Hellbore and Picrorhiza.  

What are the benefits of kutki powder for liver disease? 

Although more research is required to understand the benefits of kutki for fatty liver, there are many kutki uses in ayurveda for managing liver diseases. Kutki benefits in managing viral hepatitis, recurrent fever, and alcohol-induced fatty liver. 

What precautions should be taken while consuming kutki formulations? 

 Kutki formulations should be stored at 50 degrees for three months. Additionally, it should not be consumed during pregnancy. It is advised that children, the elderly and breastfeeding mothers should consult a doctor regarding kutki side effects before consuming it.  

What are the contraindications of kutki powder?   

Kutki powder should not be consumed by pregnant women. It can cause serious side effects in the mother as well as the unborn baby. So, it is best avoided in any form.

References

  1. Almeleebia TM, Alsayari A, Wahab S. Pharmacological and clinical efficacy of picrorhiza kurroa and its secondary metabolites: A comprehensive review [Internet]. Molecules (Basel, Switzerland). U.S. National Library of Medicine; 2022 [cited 2022Dec22]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738980/  
  2. Kumari I, Kaurav H, Chaudhary G. Ethnobotanical Significance of Picrorhiza Kurroa (Kutki), a Threatened Species. International Journal of Research and Review. 2021 Apr 24;8(4):363–75. Available from: https://www.ijrrjournal.com/IJRR_Vol.8_Issue.4_April2021/IJRR043.pdf   
  3. R; JKLK. Anti-diabetic activity of Picrorrhiza Kurroa extract [Internet]. Journal of ethnopharmacology. U.S. National Library of Medicine; [cited 2022Dec22]. Available from: https://pubmed.ncbi.nlm.nih.gov/10619377/  
  4. RA; RVGGK. Antioxidant and anti-neoplastic activities of Picrorhiza Kurroa extracts [Internet]. Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association. U.S. National Library of Medicine; [cited 2022Dec22]. Available from: https://pubmed.ncbi.nlm.nih.gov/21081148/   
  5. Raut A, Dhami-Shah H, Phadke A, Shindikar A, Udipi S, Joshi J, Vaidya R, Vaidya ADB. Picrorhiza kurroa, Royle ex Benth:Traditional uses, phytopharmacology, and translational potential in therapy of fatty liver disease. J Ayurveda Integr Med. 2023 Jan-Feb;14(1):100558. doi: 10.1016/j.jaim.2022.100558. Epub 2022 Jun 2. PMID: 35659739; PMCID: PMC10105242. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10105242/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation of the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Chayote: Uses, Benefits, Side Effects & More  

Introduction

Chayote, scientifically known as Sechium edule, is a climbing plant belonging to the Cucurbitaceae family. Initially grown in Mexico and Guatemala, it was later introduced to the United States, Europe, Africa, China, and South-Asian countries. Nowadays, it is grown throughout the world in tropical and subtropical areas1

There are two major varieties of chayote plants, namely, the commercial variety and the wild type.1 Commonly chayote is known by different names such as vegetable pear, cho cho, chow-chow, sayote, pear squash, christophene, chuchu, guisquil, and iskus2

The plant’s edible parts are its fruits, stems, leaves, and roots. Chayote fruits are bright green and pear-shaped. There are many medicinal benefits of chayote owing to the bioactive compounds such as sterols, cucurbitacins and polyphenol compounds present in it1.  

Chayote Nutritional Value

Chayote has high nutrient value and is loaded with essential vitamins, minerals, fibers, and antioxidants. According to the US Department of Agriculture, the nutritional value of 100g of Chayote is as follows4:   

Potential Uses of Chayote for Overall Health

Existing studies suggest that chayote may offer the following potential benefits as a part of overall health:   

1. Potential Uses of Chayote for the Heart Health

Diets high in saturated fats can lead to fat build-up in the arteries, making it harder for the heart to pump blood efficiently. Chayote is low in fat and contains fibre and antioxidants, which may support heart health by helping to manage cholesterol levels as part of a balanced diet.  

A study8 found that extracts of Chayote help in the treatment of heart diseases by influencing the function of the smooth muscles of the arteries. Additionally, chayote is rich in fibres, and studies have shown that dietary fibres may prevent heart diseases9. However, if you have a heart condition, don’t replace your medications with chayote. It is best to consult a doctor and seek treatment accordingly.  

2. Potential Uses of Chayote for Diabetes

Diabetes is a medical condition in which blood has high levels of sugar. A review study found that the natural antioxidants in the vegetables like chayote may maintain glucose balance in the body and reduce sugar spikes after meals10. Additionally, the rich fibrous content of the chayote may help in managing blood sugar levels by slowing down the absorption of carbohydrates, resulting in reduced blood sugar levels after eating.  The chayote extracts may reduce blood sugar levels3. Consult a doctor to know if consuming chayote is right for you in supporting diabetes management.   

3. Potential Uses of Chayote in Pregnancy 

Women require specific nutrients like folate, iron, calcium, and essential vitamins to support a healthy pregnancy2. Chayote is a good source of folate, a vital nutrient during pregnancy that supports the healthy development of the baby’s brain and spinal cord. Research has shown that adequate folate intake may help reduce the risk of premature delivery and neural tube defects. Including chayote as part of a balanced diet may contribute to a healthy pregnancy. It can also help in lowering blood pressure in pregnant women; however, it is important to consult a healthcare professional rather than relying on self-medication11,12.  

4. Potential Uses of Chayote in Cancer 

Cancer is a medical condition where the body’s cells abnormally multiply, affecting its normal functioning. A study5 found that chayote may inhibit the multiplication of cancerous cells and promote cell death. Studies13 have also found that chayote fruits may help in the treatment of acute myeloid leukemia. Additionally, the chayote leaf extracts may inhibit the multiplication of breast cancer cells14. However, if you suspect cancer, instead of self-medicating, you should consult a doctor to understand chayote leaves’ health benefits and seek treatment accordingly.   

5. Potential Uses of Chayote for Anti-ageing  

Antioxidants may protect the body against cellular damage and reduce inflammation. A study has shown that free radicals may damage the body cells, reduce the body’s functioning over time, and accelerate ageing. Studies15 show that antioxidants from chayote can protect the cells from harmful effects of UV rays, reduce cell damage, and slow down the signs of ageing16. Chayote is rich in antioxidants and vitamin C and may benefit the skin by promoting collagen production that may reduce the visible signs of ageing such as wrinkles, fine lines, and pigmentations1. However, you should always consult a doctor instead of self-medicating to get chayote leaves benefits.   

6. Potential Uses of Chayote in Fatty Liver 

Fatty liver disease occurs when excessive fat accumulates in the liver, affecting its normal function. Some studies have indicated that extracts from chayote may help protect liver tissue by reducing fat deposition. While these findings are promising, further research is needed, and dietary changes should always be discussed with a healthcare professional7. More research is required to understand how chayote squash benefits liver functioning. If you have a fatty liver, you should consult a doctor instead of self-medicating. 

7. Other Potential Uses of Chayote

Other potential uses of chayote squash vegetable are as follows:   

In traditional medicine, decoctions made from the leaves or fruit of chayote have been used for their potential diuretic properties. They have been traditionally applied to help relieve burning sensations during urination, support kidney health, and manage certain respiratory discomforts. However, these uses are based on traditional practices, and scientific evidence is limited. Anyone considering such remedies should consult a qualified healthcare professional8

Chayote fruit is rich in vitamin A and E, both of which are essential for normal bodily functions. Vitamin A may support good vision, reproductive health, and the health of your blood, while vitamin E might be crucial for maintaining a healthy brain and glowing skin19.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Chayote?

Chayote can be used in the following ways:  

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.     

Side Effects of Chayote

No significant side effects have been scientifically documented in relation to the moderate consumption of chayote as part of a normal diet. It is well-tolerated by most people and is not known to cause adverse effects when properly prepared and consumed in typical amounts. 

Precautions to Take with Chayote

General precautions must be followed while consuming chayote. Here is a list of a few precautions.    

Also Read: Ber Fruit (Jujube): Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

There is not enough evidence on the interaction of the chayote extracts with other drugs. Further studies are required. Therefore, you must consult your doctor if you are on any other medication before consuming chayote.    

There is a traditional belief that chayote leaves may help in the natural elimination of kidney stones. They have been used in some cultures with the view that their properties might support the breakdown of kidney stones. However, scientific research on this specific use is currently limited19. It is important to consult a medical professional for proper diagnosis and treatment of kidney stones rather than relying solely on traditional remedies.

Dr. Rajeev Singh, BAMS

Chayote Recipes

Chayote recipes can be enjoyed in both savoury and sweet dishes. Here are a few chayote recipe ideas to inspire your culinary creativity: 

1. Chayote Salad

Make a refreshing salad by thinly slicing chayote and mixing it with your favourite vegetables, such as tomatoes, onions, and bell peppers. Toss the salad with a zesty vinaigrette dressing for a crisp and healthy side dish. 

2. Stuffed Chayote

Stuffed chayote is a flavourful and satisfying dish in which chayote halves are filled with a seasoned mixture, commonly containing ground meat, vegetables, and herbs. The filled chayotes are then baked or cooked until tender, allowing the mild flavour of the vegetable to blend beautifully with the savoury stuffing. This dish serves as a hearty, protein-rich main course and a wholesome addition to any meal. 

3. Chayote Fries

Cut chayote into strips, season with your preferred spices, and bake or air-fry for a nutritious alternative to traditional potato fries. Sliced chayote is seasoned and baked until it becomes crisp and golden brown, offering a delightful snack or side dish with a unique flavour and texture. These chayote fries are a healthier choice for those looking to enjoy a satisfying, low-calorie treat. 

4. Chayote Squash 

Chayote squash, also known as vegetable pear or mirliton, is a green, wrinkled fruit commonly used in culinary dishes. It has a mild, crisp texture and is versatile in both savoury and sweet chayote squash recipes. Chayote is known for its high fibre content and can be cooked or eaten raw, making it a nutritious addition to a balanced diet. Its subtle flavor allows it to absorb the tastes of the dishes it’s incorporated into, making it a popular choice in various cuisines around the world. 

5. Chayote Desserts

Chayote desserts offer a unique and healthy twist to sweet treats. From chayote pies to puddings, these creations incorporate the mild, crisp texture of chayote into delightful, low-calorie desserts. With their versatility, chayote desserts are gaining popularity among those looking for a nutritious alternative to traditional sweets. 

Experiment with these chayote recipes to make the most of chayote’s unique flavour and versatility. Whether you’re looking for a healthy side dish, a filling main course, or a sweet treat, chayote can be a delightful addition to your culinary repertoire. 

Also Read: Pudina (Mint): Uses, Benefits, Side Effects & More!

Conclusion 

Chayote is a nutrient-rich vegetable with potential health benefits, including heart support, blood sugar regulation, and antioxidant protection. It can be a healthy addition to your diet when consumed in moderation. However, consult a doctor before using it for medicinal purposes. 

Frequently Asked Questions (FAQs)

What part of the chayote plant is edible?

The fruit, including the seeds, rind, peel, and flesh are edible. You can also eat its tendrils, flowers, and roots. There are several health benefits of eating chayote raw or cooked.   

Is chayote good for diabetes?

Yes, chayote benefits people with diabetes by lowering their blood sugar levels.  Additionally, the nutritional benefits of chayote help in slowing the absorption of carbohydrates which further reduces food intake, weight and thereby, sugar intake. However, you should consult a doctor before using chayote for weight loss and diabetes.   

What are chayote juice benefits? 

There are many health benefits of chayote juice. The extract from chayote fruit may help in promoting healthy digestion, regulating blood pressure, and slowing down the ageing process. Many people prefer having chayote juice for weight loss after working out. However, you should consult a doctor before using chayote for skin, high blood pressure, and digestive issues.   

Is chayote good for the kidney?

Chayote may reduce the formation of kidney stones. However, you should consult a doctor before self-medicating chayote for kidney stones.  

What are the health benefits of chayote?

Chayote is widely used in the pharmaceutical and cosmetic industries. It promotes heart health, prevents cancer, lowers blood pressure, regulates blood sugar, prevents fat accumulation in the liver, fights inflammation, and slows the ageing process. However, you should consult a doctor before utilising chayote benefits for high blood pressure and overall health.  

What is chayote?

Chayote is a green, wrinkled vegetable, scientifically known as Sechium edule. It belongs to the Cucurbitaceae family and is often used in various culinary dishes. It’s also known as mirliton squash, chocho, or guisquil in different regions. 

How to eat chayote? 

To eat chayote, you can peel and slice it for use in salads, stir-fries, or as a raw snack. It can also be cooked by boiling, steaming, or roasting. Chayote is versatile and pairs well with various flavors and cuisines. 

Is chayote good for babies?

Chayote benefits for baby become evident as it can be a nutritious addition to a baby’s diet, offering essential vitamins and dietary fiber. However, it’s crucial to consult with a pediatrician before introducing new foods to ensure they are suitable for the baby’s age and specific dietary needs. 

Is chayote good for uric acid?

Chayote is considered a relatively safe choice for individuals with high uric acid levels, as it is low in purines that can contribute to uric acid production. However, individual responses may vary, so it’s advisable to monitor how your body reacts to chayote and consult a healthcare provider or dietitian for personalized dietary recommendations. 

Is chayote high in potassium? 

Chayote is relatively low in potassium compared to many other fruits and vegetables, making it a suitable choice for individuals who need to restrict their potassium intake, such as those with kidney issues. However, portion control and overall dietary considerations are still important for individuals with specific potassium restrictions. 

References

  1. Pu Y-T, Luo Q, Wen L-H, Li Y-R, Meng P-H, Wang X-J, et al. Origin, evolution, breeding, and omics of chayote, an important Cucurbitaceae vegetable crop [Internet]. Front Plant Sci [Internet]. 2021 [cited 2025 Jun 4];12:739091. Available from: https://www.frontiersin.org/articles/10.3389/fpls.2021.739091/full 
  2. Vieira EF, Pinho O, Ferreira IMPLVO, Delerue-Matos C. Chayote (Sechium edule): A review of nutritional composition, bioactivities and potential applications. Food Chem. 2019 Mar 1;275:557-568. doi: 10.1016/j.foodchem.2018.09.146. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0308814618317230?via%3Dihub    
  3. Gavia-García G, Hernández-Álvarez D, Arista-Ugalde TL, Aguiñiga-Sánchez I, Santiago-Osorio E, Mendoza-Núñez VM, Rosado-Pérez J. The Supplementation of Sechium edule var. nigrum spinosum (Chayote) Promotes Nrf2-Mediated Antioxidant Protection in Older Adults with Metabolic Syndrome. Nutrients. 2023 Sep 22;15(19):4106. doi: 10.3390/nu15194106. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10574595/ 
  4. U.S. Department of Agriculture, Agricultural Research Service. FoodData Central. Chayote, fruit, raw [Internet]. Beltsville (MD): USDA; 2019 Apr 1 [cited 2025 Jun 4]. Available from: https://fdc.nal.usda.gov/food-details/170402/nutrients  
  5. Salazar-Aguilar S, Ruiz-Posadas LDM, Cadena-Iñiguez J, Soto-Hernández M, Santiago-Osorio E, Aguiñiga-Sánchez I, et al. Sechium edule (Jacq.) Swartz, a new cultivar with antiproliferative potential in a human cervical cancer HeLa cell line [Internet]. Nutrients. U.S. National Library of Medicine; [cited 2022 Dec 16]. Available from: https://pubmed.ncbi.nlm.nih.gov/28757593/ 
  6. Ordoñez AAL, Gomez JD, Cudmani NM, Vattuone MA, Isla MI. Antimicrobial activity of nine extracts of Sechium edule (Jacq.) Swartz. Microb Ecol Health Dis. 2003;15:33–39. Available from: https://core.ac.uk/download/pdf/323211428.pdf  
  7. Yang MY, Chan KC, Lee YJ, Chang XZ, Wu CH, Wang CJ. Sechium edule Shoot Extracts and Active Components Improve Obesity and a Fatty Liver That Involved Reducing Hepatic Lipogenesis and Adipogenesis in High-Fat-Diet-Fed Rats. J Agric Food Chem. 2015 May 13;63(18):4587-96. doi: 10.1021/acs.jafc.5b00346. Available from: https://pubmed.ncbi.nlm.nih.gov/25912298/  
  8. Ibarra-Alvarado C, Rojas A, Mendoza S, Bah M, Gutiérrez DM, Hernández-Sandoval L, et al. Vasoactive and antioxidant activities of plants used in Mexican traditional medicine for the treatment of cardiovascular diseases [Internet]. Pharm Biol [Internet]. [cited 2022 Dec 16];48(5):468–75. Available from: https://pubmed.ncbi.nlm.nih.gov/20645769/  
  9. McRae MP. Dietary fiber is beneficial for the prevention of cardiovascular disease: an umbrella review of meta-analyses [Internet]. J Chiropr Med. 2017 Dec;16(4):289–99 [cited 2025 June 04]. Available from: https://pubmed.ncbi.nlm.nih.gov/29276461/ 
  10. Tiwari AK. Revisiting “Vegetables” to combat modern epidemic of imbalanced glucose homeostasis. Pharmacogn Mag. 2014;10(Suppl 2):S207–S213. Available from: https://phcog.com/article/view/2014/10/38s/s207-s213     
  11. Greenberg JA, Bell SJ, Guan Y, Yu YH. Folic Acid supplementation and pregnancy: more than just neural tube defect prevention. Rev Obstet Gynecol. 2011 Summer;4(2):52-9. Available from: https://pubmed.ncbi.nlm.nih.gov/22102928/ 
  12. Fauziah NA, Hidajati K, Soejoenoes A. The effect of chayote extract (Sechium edule) on blood pressure in pregnant women with hypertension. Indones J Med. 2019;4(3):266–77. doi:10.26911/theijmed.2019.04.03.10. Available from: https://www.cabidigitallibrary.org/doi/pdf/10.5555/20203262858  
  13. Aguiñiga-Sánchez I, Soto-Hernández M, Cadena-Iñiguez J, Ruíz-Posadas Ldel M, Cadena-Zamudio JD, González-Ugarte AK, Steider BW, Santiago-Osorio E. Fruit extract from a Sechium edule hybrid induce apoptosis in leukaemic cell lines but not in normal cells. Nutr Cancer. 2015;67(2):250-7. doi: 10.1080/01635581.2015.989370. Available from: https://pubmed.ncbi.nlm.nih.gov/25611564/ 
  14. Elavarasan, N., Kokila, K., Inbasekar, G., and Sujatha, V. (2016). Evaluation of photocatalytic activity, antibacterial and cytotoxic effects of green synthesized ZnO nanoparticles by Sechium edule leaf extract. Res. Chem. Intermediat. 43, 1–16. doi: 10.1007/s11164-016-2830-2. Available from: https://link.springer.com/article/10.1007/s11164-016-2830-2 
  15. Sergiev PV, Dontsova OA, Berezkin GV. Theories of aging: an ever-evolving field.   Acta Naturae. 2015 Jan-Mar;7(1):9-18. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4410392/  
  16. Metral E, Rachidi W, Damour O, Demarne F, Bechetoille N. Long-term Genoprotection Effect of Sechium edule Fruit Extract Against UVA Irradiation in Keratinocytes. Photochem Photobiol. 2018 Mar;94(2):343-350. doi: 10.1111/php.12854. Available from: https://pubmed.ncbi.nlm.nih.gov/29110298/  
  17. Fauziah, N. A., Hidajati, K., and Soejoenoes, A. (2019). The effect of chayote extract (Sechium edule) on blood pressure in pregnant women with hypertension. Indonesian J. Med. 4, 266–277. doi: 10.26911/theijmed.2019.04.03.10. Available from: https://onlinelibrary.wiley.com/doi/10.1155/2014/594326  
  18. Del Ángel Coronel OA, León-García E, Vela-Gutiérrez G, De la Cruz Medina J, García-Varela R, García HS. Chayote (Sechium edule (Jacq.) Swartz). In: Yahia EM, editor. Fruit and Vegetable Phytochemicals: Chemistry and Human Health. 2nd ed. Hoboken (NJ): Wiley-Blackwell; 2017. p. 1025–38. doi:10.1002/9781119158042.ch47. Available from: https://www.researchgate.net/publication/320428959_Chayote_Sechium_edule_Jacq_Swartz_Chemistry_and_Human_Health_2nd_Edition  
  19. Pu YT, Luo Q, Wen LH, Li YR, Meng PH, Wang XJ, Tan GF. Origin, evolution, breeding, and omics of chayote, an important Cucurbitaceae vegetable crop. Front Plant Sci. 2021 Sep 24;12:739091. doi: 10.3389/fpls.2021.739091. PMID: 34630492; PMCID: PMC8497889. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497889/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof. 

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Kodo Millets: Uses, Benefits, Side Effects, And More

Introduction

Kodo millets, botanically known as Paspalum scrobiculatum, is a traditional grain belonging to the Poaceae family. It is often referred to in English as rice grass, ditch millet, or cow grass. Regionally, it is known as araka in Telugu and kodra in Marathi. The grains of kodo millet vary in colour from light red to dark grey and are cultivated annually.

The history of kodo millet cultivation in India dates back approximately 3,000 years. In addition to India, it is also grown in countries such as Russia, China, various parts of Africa, and Japan. Within India, it is primarily cultivated in the states of Madhya Pradesh, Tamil Nadu, Karnataka, Gujarat, and Chhattisgarh. 

Among all the millets available, Kodo millets are well known for its resilience to drought and its ability to produce a reasonable yield within a short period. As a result, it holds significant economic importance, particularly in regions where agriculture is challenged by water scarcity. India leads the world in the production of kodo millet

Kodo millets are cultivated in the kharif season (monsoon season) and are available in different varieties, namely Indira kodo, Jawahar kodo, and TNAU. Kodo millets are processed into value-added foods and drinks. While kodo millet is appreciated for its nutritional content and is a staple in many traditional diets, it is important to note that any health-related benefits should be interpreted with caution. The grain may form part of a balanced diet, but it is not intended to diagnose, treat, cure, or prevent any medical condition. Individuals with specific health concerns should consult a qualified healthcare professional before making dietary changes1,2.

Did you know?

Nutritional Value of Kodo Millets

Kodo millet is a nutritious grain containing carbohydrates, protein, and dietary fibre. It also provides B-vitamins such as niacin and riboflavin, along with minerals like calcium, iron, and phosphorus. Additionally, it contains natural phytochemicals, including antioxidants and phenolic compounds such as vanillic acid, gallic acid, tannins, and ferulic acid.

Here are the nutritional components of kodo millet per 100 grams2:

In my own viewpoint, this humble grain is not only delicious but also has some surprising health benefits. Kodo millet is believed to have properties that might help in asthma. Not only that it might be beneficial for people suffering from migraine.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Kodo Millets

Scientific studies have explored various characteristics of kodo millet. Some of the observed and researched properties are outlined below:

Let me tell you that these tiny grains might be heroes for your gallbladder! Kodo millets, thanks to their high fibre content, have the potential to avoid the formation of gallstones12.

Dr. Rajeev Singh, BAMS

Potential Uses of Kodo Millets for Overall Health

Some of the potential benefits of kodo millets are described as follows:  

1. Potential Uses of Kodo Millets on Lipid Profile

Hyperlipidemia is the elevation in lipid components like triglycerides, total cholesterol, and reduced levels of high-density lipoprotein. An animal study4 investigated the potential effects of kodo millet on lipid levels in rats. The findings suggested that kodo millet consumption was associated with reduced levels of total cholesterol, triglycerides, and low-density lipoprotein (LDL), while increasing HDL levels. However, we need more clinical studies to support these claims in humans.  

2. Potential Uses of Kodo Millets for Bacterial Infections

Literature shows that the consumption of kodo millets may have the potential to manage bacterial infections. A review5 conducted noted that kodo millets could inhibit the growth of bacteria like S.aureus, Bacillus cereus, Leuconostoc mesenteroides and Enterococcus faecalis which are organisms associated with infections such as urinary tract infections and diarrhoea. However, we need more studies to support these claims. 

3. Potential Uses of Kodo Millets for Type-2 Diabetes

Type-2 diabetes is a metabolic disorder characterised by an increase in blood glucose due to decreased production or resistance to a hormone called insulin which regulates blood glucose. A review6 conducted suggested that kodo millets may have the potential to decrease blood glucose levels. This effect is attributed to polyphenols, which inhibit enzymes that break down carbohydrates into simpler sugars and increase blood glucose. Additionally, kodo millets have a low glycaemic index. Certain phenolic compounds found in kodo millets have been studied for their potential to inhibit enzymes such as aldose reductase. This enzyme is involved in the conversion of glucose to sorbitol, an accumulation of which has been linked to diabetic complications, including cataract formation. However, there are not enough studies to support these claims and therefore should only be used under the supervision of a medical professional.

4. Potential Uses of Kodo Millets in Cancer

Literature studies have supported the use of kodo millets may possess properties to reduce the risk of cancers. A review study2 indicated that kodo millets may potentially reduce cancer initiation and progression. This anti-cancer effect is attributed to the presence of phenolic acids, phytic acids, and tannins in the grain. However, we need more scientific evidence to support these claims. 

5. Potential Uses of Kodo Millets in Malnutrition

Malnutrition is defined as the deficiency, excess, or imbalance in the intake of energy or nutrients. The term malnutrition addresses 3 broad groups of conditions as follows:

Kodo millets are highly nutritious due to the presence of carbohydrates, proteins, dietary fibres, vitamins (like niacin and riboflavin) and minerals (like calcium, iron, and phosphors). Kodo millets are also rich in antioxidants and phenolic compounds like vanillic acid, gallic acid, tannins, and ferulic acid. A review study6 suggested that kodo millets may help manage micronutrient-related malnutrition. Thus, the consumption of Kodo millet may positively impact malnutrition. Though scientific evidence to support these claims is limited, we need more studies to ascertain these claims with better results.

6. Other Potential Uses of Kodo Millets

Though there are studies that show the benefits of kodo millets in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kodo millets on human health.  

In my knowledge, kodo millets with their abundance of nutrients, have been found to have great benefits. They’re not just for filling your plate; they might actually help with inflammation, haemorrhages (excessive bleeding), and general weakness10.

Dr. Smita Barode, B.A.M.S, M.S.

How to Use Kodo Millets?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

I have read in a research paper that the dried ethanol extract of kodo millet husk, when consumed, may have interesting effects on both animals and humans. It has been observed that this extract might cause a calming effect, leading to tranquillity, in various animal species. Additionally, when a human volunteer took the extract, they also experienced possible drowsiness11.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

Side Effects of Kodo Millets

A few side effects related to the consumption of kodo millets include:  

However, if you experience any adverse reactions to Kodo millet, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Precautions to Take with Kodo Millets

Eating kodo millet is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions: 

Interactions with Other Drugs

Therefore, you must always seek the advice of your Ayurvedic physician before incorporating kodo millet into your routine, especially if you are on medication. They can provide personalised advice based on your medical history and current treatment plan, helping to avoid any potential interactions.

Conclusion 

Kodo millet stands out as a grain with a rich history, impressive nutritional profile, and potential health benefits. Its drought resistance and economic value make it a vital crop, particularly in water-scarce regions. While research continues to explore its medicinal properties, incorporating kodo millet into a balanced diet may support overall health, when used under proper guidance.

Frequently Asked Questions (FAQs)

What is the name of Kodo millet in Marathi?

Kodo millet is called “Kodra” in Marathi. 

What are the different varieties of Kodo millets available in the market?

The different kodo millet varieties available in the market include Indira kodo, Jawahar kodo, and TNAU.

Should kodo millets be soaked before use?

Yes, kodo millets contain certain naturally occurring compounds, known as anti-nutrients, such as phytic acid and polyphenols. These substances reduce the availability of nutritional components and processing methods like soaking will help decrease the level of these anti-nutrients.

Can we use Kodo millet for weight loss?  

Yes, as kodo millet is low in fat content and high in protein and fibre, it increases satiety and reduces overeating, and may help in weight loss.

What are the side effects of Kodo millets?

Contaminated or improperly stored kodo millet may cause kodo poisoning, potentially leading to elevated liver enzymes, nausea, vomiting, and, in severe cases, unconsciousness. The grain
also contains goitrogens, which may interfere with thyroid function and contribute to goitre if consumed excessively without adequate iodine intake.

References

  1. Bunkar et al. Nutritional, Functional Role of Kodo Millet and its Processing: A Review, International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 10 Number 01 (2021). Available at:  https://doi.org/10.20546/ijcmas.2021.1001.229 
  2. NUTRI CEREALS- IYoM 2023. Available at: https://nutricereals.dac.gov.in/
  3. Naturally Yours , Kodo Millet – nutrition, benefits and recipes, Naturally Yours. Available at: https://naturallyyours.in/blogs/blog/kodo-millet-nutrion-benefits-and-recipes
  4. Satish Narra, Bandenawaz Ramadurg, Saraswathi CD. Antihyperlipidemic Activity of Paspalum scrobiculatum L. Grains Extract in Albino Rats. Research J. Pharmacology and Pharmacodynamics. 2013; 5(6): 362-370. Available at: https://rjppd.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacology%20and%20Pharmacodynamics;PID=2013-5-6-20 
  5. Sharma S, Sharma N, Handa S, Pathania S. Evaluation of health potential of nutritionally enriched Kodo millet (Eleusine coracana) grown in Himachal Pradesh, India. Food Chem. 2017 Jan 1;214:162-168. doi: 10.1016/j.foodchem.2016.07.086. Epub 2016 Jul 12. PMID: 27507461. Available at: https://pubmed.ncbi.nlm.nih.gov/27507461/ 
  6. Wang, Han et al. “Effect of Different Processing Methods on the Millet Polyphenols and Their Anti-diabetic Potential.” Frontiers in nutrition vol. 9 780499. 11 Feb. 2022, doi:10.3389/fnut.2022.780499. Available at: https://www.researchgate.net/publication/358534642_Effect_of_Different_Processing_Methods_on_the_Millet_Polyphenols_and_Their_Anti-diabetic_Potential 
  7. Vinoth, A, and R Ravindhran. “Biofortification in Millets: A Sustainable Approach for Nutritional Security.” Frontiers in plant science vol. 8 29. 23 Jan. 2017, doi:10.3389/fpls.2017.00029. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253353/ 
  8. Antony, Mary et al. “Potential risk of acute hepatotoxicity of kodo poisoning due to exposure to cyclopiazonic acid.” Journal of ethnopharmacology vol. 87,2-3 (2003): 211-4. doi:10.1016/s0378-8741(03)00146-6. Available at: https://pubmed.ncbi.nlm.nih.gov/12860310/ 
  9. Sonali et al. “Millets – Miracle grain”. Rashtriya Krishi | Vol. 15 (1)| Jun., 2020. Available at: http://researchjournal.co.in/online/RKE/RKE-15(1)/15_57-60.pdf 
  10. Bhatia G, Joshi S, Barve A, Nema RK, Joshi A, Gehlot S. Phytochemical Studies of the Grains of Paspalum scrobiculatum. Int J Pharm Clin Res. 2010;2(2):66-67.Available at: https://www.researchgate.net/publication/312041797_Phytochemical_Studies_of_the_Grains_of_Paspalum_scrobiculatum
  11. Bhide NK. Pharmacological study and fractionation of Paspalum scrobiculatum extract. British Journal of Pharmacology and Chemotherapy. 1962 Feb;18(1):7-18.Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC1482178/pdf/bripharmchem00062-0013.pdf
  12. Deshpande S S, Mohapatra D, Tripathi M K, Sadvatha R H. Kodo millet-nutritional value and utilization in Indian foods [Internet]. Journal of Grain Processing and Storage. 2015 [cited 2025 Oct 9];2(2):16-23. Available from:https://www.academia.edu/72641412/Kodo_millet_nutritional_value_and_utilization_in_Indian_foods

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof. 

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Red Rice: Uses, Benefits, Side Effects & More

Introduction

According to Balinese mythology, a divine bird was sent to Earth carrying four seeds coloured red, white, black, and yellow. During its journey, the bird consumed the yellow seed, leaving only the red, white, and black ones. These are believed to represent the various types of rice grains known today. 

Among them, red rice stands out for its distinctive colour and traditional significance. Commonly referred to by different names such as Oryza longistaminata, Matta rice, Palakkadan Matta rice, and Rakthashali in Ayurveda, red rice owes its rich hue to the presence of anthocyanin, a natural antioxidant pigment. 

Red rice can appear in several forms, which include wild, weedy, or cultivated and may be partially or fully covered with husk. It has been traditionally cultivated in regions such as Sri Lanka, China, the United States, Korea, and India. Within India, red rice is grown in various states, including Karnataka, Tamil Nadu, Kerala, Odisha, and Madhya Pradesh. Notable varieties include Patni from Maharashtra, Matali and Jatu from Kullu, and Matta from Kerala1.  

Did You know? 

Nutritional Value of Red Rice

Red rice is a nutritional powerhouse. It contains proteins, carbohydrates, mono-unsaturated fatty acids, vitamins, and minerals like zinc and iron. Additionally, red rice is a source of polyphenols, including vanillic acid and ferulic acid, as well as antioxidants like anthocyanins, proanthocyanidins, and flavonoids, which are responsible for its characteristic colour. The nutritional components of red rice per 100 grams are given below2:   

Properties of Red Rice

Scientific studies have examined various aspects of red rice, and its consumption has been associated with several beneficial nutritional properties. Some of these observed characteristics are outlined below, based on available research and traditional dietary usage. 

Potential Uses of Red Rice for Overall Health

Some of the potential benefits of red rice are described as below:  

1. Potential Uses of Red Rice in Inflammation  

Inflammation is the body’s natural defence mechanism in response to infection, stress, or tissue injury. It can be acute, such as in the case of fever, or chronic, as seen in long-term conditions like arthritis. A systematic review12 has reported that red rice may exhibit anti-inflammatory and antioxidant properties in certain experimental settings. Antioxidants are known to help protect cells from oxidative stress and may assist in reducing inflammatory responses. These potential effects are attributed to the presence of naturally occurring compounds in red rice, such as gamma-oryzanol, flavonoids, and phenolic compounds3.   

While such findings are of interest, it is important to note that more robust scientific studies are needed to confirm these observations. At present, there is insufficient clinical evidence to support any definitive health claims regarding the management or treatment of inflammatory conditions through the consumption of red rice.  

2. Potential Uses of Red Rice in Breast Cancer

Breast cancer is one of the most commonly diagnosed cancers affecting women worldwide. Some preliminary research13 has investigated the potential effects of red rice on breast cancer cells in laboratory settings. Findings from these studies suggest that certain compounds present in red rice, such as polyphenols, particularly proanthocyanidins may influence cellular processes related to cancer progression. For example, red rice extracts have been observed to inhibit the activity of interleukin-6 (IL-6), a protein associated with cell growth and may also play a role in reducing cell migration in vitro4.  

However, it is important to emphasise that these studies are experimental in nature, and the results have not been confirmed through large-scale clinical trials. At this stage, there is no conclusive evidence to support any preventive or therapeutic claims related to breast cancer, and further research is required. Individuals should consult with qualified healthcare professionals for medical advice or treatment..  

3. Potential Uses of Red Rice for Alopecia

Alopecia is the loss of hair or baldness. Red rice is naturally rich in protein and other nutrients, which are important for general health, including the maintenance of hair. Some experimental research5 has explored the potential impact of red rice on hair health. In one such study, red rice extract was found to inhibit the activity of the enzyme 5-alpha reductase, which is associated with hair loss in certain conditions. These findings suggest a possible link between compounds found in red rice and reduced hair shedding in laboratory models. However, these results are preliminary and have not been confirmed through extensive human studies. At present, there is insufficient scientific evidence to support the use of red rice in managing alopecia, and individuals experiencing hair loss are advised to seek guidance from a qualified medical professional.  

4. Potential Uses of Red Rice in Type-2-Diabetes

Type 2 diabetes is characterised by elevated blood glucose levels either due to a decreased insulin level or resistance of the body to insulin (a hormone that regulates blood glucose levels). A study6 in 2020 investigated the potential effects of red rice in a diabetic mouse model. The findings suggested that red rice consumption may be associated with improved insulin sensitivity and a lower glycaemic response in that experimental context. These observations were attributed to the naturally low glycaemic index of red rice and the presence of certain bioactive compounds. While these results are scientifically noteworthy, 

 it is important to recognise that the study was conducted on animals, and further well-designed clinical trials in humans are necessary to confirm these outcomes. At present, there is not enough evidence to support any definitive health claims regarding the management of Type 2 diabetes through red rice consumption. Individuals with diabetes should consult a qualified healthcare provider for appropriate dietary and medical guidance.  

5. Potential Uses of Red Rice on Dyslipidemia

Dyslipidemia is characterised by elevated cholesterol, including increased low-density lipoprotein, often referred to as ‘bad’ cholesterol, and decreased high-density lipoprotein (HDL), known as ‘good’ cholesterol. A review of existing research7 has noted that red yeast rice, which is a fermented form of red rice, may help reduce cholesterol levels by inhibiting its synthesis in the body. 

Additionally, the presence of naturally occurring phytosterols and monounsaturated fatty acids in red rice has been associated with potential benefits in managing lipid profiles. These findings suggest that red rice might have a positive effect on dyslipidemia8. However, further rigorous studies are required to establish these claims with greater scientific certainty.  

6. Potential Uses of Red Rice on Digestion

Literature indicates that diets rich in dietary fibre are generally associated with a reduced intake of fats and may contribute to improved digestive health. Traditional Chinese medicine has historically used red rice as a natural help for digestion8.  As a good source of dietary fibre, red rice may support regular bowel movements and provide relief from constipation. Furthermore, red rice is naturally low in fat while being relatively high in protein and fibre, which can promote feelings of fullness, potentially reducing overeating and supporting metabolic health. These characteristics suggest that consuming red rice could be beneficial for digestion, relief from constipation, and maintaining a healthy weight1. However, further scientific studies are needed to confirm these effects.  

7. Other Potential Uses of Red Rice

Though there are studies that show the benefits of red rice in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of red rice on human health.   

As red rice is a good source of many nutrients, including phytochemicals, which are believed to possess properties that may support skin health and potentially contribute to anti-ageing effects15.

Dr. Rajeev Singh, BAMS

How to Use Red Rice?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.    

Also Read: 14 Health Benefits of Amaranth Leaves That You Must Know

Side Effects of Red Rice

Few side effects related to the consumption of red rice include:  

However, if you experience any adverse reactions to red rice, it is advised to discontinue its use immediately and consult a doctor or the Ayurvedic physician who prescribed it. They can provide appropriate guidance based on your symptoms.” 

Certain studies14 have explored the potential of red yeast rice in supporting bone health. Preliminary findings from these studies suggest that red yeast rice may have a role in promoting bone formation.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Precautions to Take with Red Rice

Eating red rice is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions:  

Also Read: Plums (Aloo Bukhara): Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

Therefore, you must always seek the advice of your Ayurvedic physician about the possible interaction of red rice with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking.  

Also Read: Clove (Laung): Uses, Benefits, Side Effects and More!

Conclusion

Red rice is a nutrient-rich grain with potential health benefits supported by both traditional knowledge and preliminary scientific studies. While promising, its therapeutic claims require more clinical evidence for confirmation. As with any supplement, it should be consumed with caution and professional guidance. 

Frequently Asked Questions (FAQs)

Is red rice better than white rice?

Yes. In comparison with white rice, red rice is rich in zinc and iron which may offer several health benefits. 

What are the different red rice varieties?

Some famous red rice varieties include Patni of Maharashtra, Matali and Jatu of Kullu, and Matta of Kerala. 

Can red rice help in weight loss?  

Yes. Red rice is low in fat and high in protein and fibres, which increases satiety and reduces overeating, which may help in weight loss. 

What are the side effects of red rice consumption?

If red rice is fermented consumed improperly, it may be associated with a risk of liver injury. Excessive intake of red rice can lead to digestive discomfort, including indigestion, bloating, and stomach pain, primarily due to its high fibre and protein content. While red rice consumption is generally not known to cause allergic reactions, in some cases, it may be linked to symptoms such as itching, rashes, or swelling. The precise causes and mechanisms underlying these reactions are not yet fully understood. 

References

  1. Ahuja U, Ahuja S, Chaudhary N, Thakrar R. Red Rices – Past, Present, and Future. Asian Agri-History [Internet]. 2007 Oct 1 [cited 2025 May 27];11(4). Available from: https://www.researchgate.net/publication/237785312_Red_Rices_-_Past_Present_and_Future  
  2. US Department of Agriculture. FoodData Central [Internet]. Usda.gov. 2019 [cited 2025 May 27]. Available from: https://fdc.nal.usda.gov/food-details/2710838/nutrients  
  3. Agustin AT, Safitri A, Fatchiyah F. Java Red Rice (Oryza sativa L.) Nutritional Value and Anthocyanin Profiles and Its Potential Role as Antioxidant and Anti-Diabetic. Indonesian Journal of Chemistry [Internet]. 2021 Aug 3 [cited 2025 May 27];21(4):968. Available from: https://www.researchgate.net/publication/353975212_Java_Red_Rice_Oryza_sativa_L_Nutritional_Value_and_Anthocyanin_Profiles_and_Its_Potential_Role_as_Antioxidant_and_Anti-Diabetic  
  4. Pintha, Komsak et al. “Proanthocyanidin in red rice inhibits MDA-MB-231 breast cancer cell invasion via the expression control of invasive proteins.” Biological & pharmaceutical bulletin vol. 38,4 (2015): 571-81. doi:10.1248/bpb.b14-00719. Available at: https://pubmed.ncbi.nlm.nih.gov/25735761/  
  5. Jeng et al. (2012). Agronomic, molecular and antioxidative characterization of red- and purple-pericarp rice (Oryza sativa L.) mutants in Taiwan. Journal of Cereal Science. 56. 425–431. 10.1016/j.jcs.2012.05.015. Available at: https://www.mdpi.com/2079-9284/9/6/111  
  6. Yagi, Takakazu et al. “Red rice kojiextract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in skeletal muscle in two diabetic mouse models.” Food & nutrition research vol. 64 10.29219/fnr.v64.4226. 8 Oct. 2020, doi:10.29219/fnr.v64.4226. Available at: https://pubmed.ncbi.nlm.nih.gov/33240034/  
  7. Shamim, Shariq et al. “Red yeast rice for dysipidemia.” Missouri medicine vol. 110,4 (2013): 349-54. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179893/  
  8. Musselman ME, Pettit RS, Derenski KL. A Review and Update of Red Yeast Rice. Journal of Evidence-Based Complementary & Alternative Medicine [Internet]. 2011 Dec 4 [cited 2025 May 27];17(1):33–9. Available from: https://journals.sagepub.com/doi/full/10.1177/2156587211429703  
  9. Mazzanti, Gabriela et al. “Adverse reactions to dietary supplements containing red yeast rice: assessment of cases from the Italian surveillance system.” British journal of clinical pharmacology vol. 83,4 (2017): 894-908. doi:10.1111/bcp.13171. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346868/  
  10. Jeon, You Hoon et al. “Identification of major rice allergen and their clinical significance in children.” Korean journal of pediatrics vol. 54,10 (2011): 414-21. doi:10.3345/kjp.2011.54.10.414. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250595/  
  11. Twarużek, Magdalena et al. “Dietary Supplements Based on Red Yeast Rice-A Source of Citrinin?.” Toxins vol. 13,7 497. 17 Jul. 2021, doi:10.3390/toxins13070497. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310238/
  12. Limtrakul P, Yodkeeree S, Pitchakarn P, Punfa W. Anti‑inflammatory effects of proanthocyanidin‑rich red rice extract via suppression of MAPK, AP‑1 and NF‑κB pathways in Raw 264.7 macrophages. Nutr Res Pract. 2016 Jun;10(3):251–8. doi: 10.4162/nrp.2016.10.3.251. Epub 2016 Apr 1. PMID: 27247720; PMCID: PMC4880723. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880723/ 
  13. Chen Z, Theppawong A, Sangsawad P, Fang J, Ye H, Deng S, Yang M, Gao J, Kraithong S. Bioactive compounds in colored rice: exploring natural agents for cancer prevention in vitro and rodent model studies. J Funct Foods. 2025 May;129:106875. doi: 10.1016/j.jff.2025.106875. Available from: https://www.sciencedirect.com/science/article/pii/S1756464625002178
  14. Wu B, Huang JF, He BJ, Huang CW, Lu JH. Promotion of bone formation by red yeast rice in experimental animals: a systematic review and meta‐analysis. Biomed Res Int. 2020 Aug 8;2020:7231827. doi:10.1155/2020/7231827. PMID:32832555; PMCID:PMC7429765. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429765/
  15. Baptista E, Liberal Â, Cardoso RVC, Fernandes Â, Dias MI, Pires TCSP, Calhelha RC, García PA, Ferreira ICFR, Barreira JCM. Chemical and bioactive properties of red rice with potential pharmaceutical use. Molecules. 2024 May 11;29(10):2265. doi: 10.3390/molecules29102265. PMID: 38792127; PMCID: PMC11123668. Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC11123668/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof. 

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Halim Seeds: Uses, Benefits, Side Effects and More By Dr. Rajeev Singh

Introduction

Halim seeds, also known as garden cress seeds, are tiny reddish-brown seeds packed with nutrition and health benefits. Used for centuries in traditional medicine and cooking, they have been valued for their medicinal properties and rich nutrient profile.

These seeds come from Lepidium sativum, an edible herb belonging to the Brassicaceae family. Originally native to Egypt, the plant is now cultivated worldwide, including in India, where it is primarily grown in Madhya Pradesh, Gujarat, Rajasthan, and Uttar Pradesh. The plant produces light pink or white flowers and tiny seed pods, which are harvested for their seeds.


Halim seeds are also known by different names across regions, such as Holan, Chandrasura, Aliv seeds, and garden cress. With their impressive nutritional value, they have gained popularity as a superfood. Let’s explore the numerous health benefits these tiny seeds have to offer1.

Nutritional Value of Halim Seeds

Halim seeds are packed with the goodness of carbohydrates, proteins, fibers and minerals like calcium, phosphorus, zinc, etc. and phytochemicals like flavonoids, phenols, lectins, tannins, glycosides, etc. The nutritional components and bioactive components of Halim seeds are mentioned below: 

Properties of Halim Seeds

Scientifically proven properties of Halim seeds include: 

Based on my experience, I have found that the extract from halim seeds shows promising potential as an antifungal agent. It has been observed to effectively inhibit the growth of various fungal species. Halim seeds may possess strong antifungal properties, which could be beneficial in the management of fungal infections.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Halim Seeds for Overall Health

Some of the potential benefits of Halim seeds are described below:  

1. Potential Uses of Halim Seeds in Type 2 Diabetes 

Type 2 diabetes is a metabolic disorder characterised by hyperglycemia (an increase in blood glucose levels) with reduced or total loss of insulin (a hormone that regulates blood glucose in the body) function.

Qusti et al. conducted a study4 in 2016 to assess the effects of Halim seeds in diabetic rats. The study showed that Halim seeds showed a significant decrease in blood glucose levels. This effect was attributed to the inhibition of molecules which inhibit the insulin pathway. This indicates that Halim seeds may help in managing diabetes. However, we need more studies to support these claims in humans.

2. Potential Uses of Halim Seeds in Bone Health 

Strong bones reduce the risk of fractures and protect vital organs like the brain and heart from damage. To build strong bones and promote bone healing in fractures, calcium and Vitamin D play an important role.

Dixit et al. conducted a study1 on rats in 2020, stating that Halim seeds may positively impact bone health and help promote bone healing in case of fractures due to the presence of calcium and phosphorus in high amounts. This indicates that Halim seed consumption may have a positive impact on bone fractures, provided more human studies are done to support these claims.

3. Potential Uses of Halim Seeds on Obesity 

Obesity is defined as an excessive or abnormal accumulation of fat in the body. A Body Mass Index (BMI)>25 kg/m2 is defined as overweight, and >30 kg/m2 is considered obese. Reducing body weight may help in managing obesity.

Dixit et al. conducted a study4 in 2020 to assess the effect of Halim seeds on obese rats; the study findings supported the use of Halim seeds for weight loss. This indicates that Halim seed consumption may help manage obesity by reducing weight. However, we need more studies to support these claims in humans.

4. Potential Uses of Halim Seeds in Breast Cancer 

Breast cancer is one of the most common cancers affecting women worldwide. Literature reviews support the use of dietary agents and a reduced risk of breast cancer.

Mahassni et al. conducted a literature review5 in 2013, stating Halim seeds contain phytochemicals like organo-sulfur compounds and phytosterols, which have antioxidant and anti-inflammatory effects and may inhibit cell multiplication, arrest the cancer cell cycle and cause apoptosis (cell death of cancer cells). This indicates that Halim seeds may exert an anti-cancer effect on breast cancer. However, there is limited evidence, and we need more studies to support these claims in humans.

5. Potential Uses of Halim Seeds on Hyperlipidemia 

Hyperlipidemia or hyperlipoproteinemia is defined as an increase in total cholesterol, a reduction in low-density lipoprotein or bad cholesterol and an increase in high-density lipoprotein or good cholesterol.

Yousef et al. conducted a study6 in 2014 to assess the effects of Halim seeds on hyperlipidemia; this study states that Halim seeds positively impacted lipid profiles. This effect is attributed to the inhibition of an enzyme, which aids the formation of cholesterol. This indicates that the consumption of Halim seeds may help manage hyperlipidemia. However, more studies should be conducted to claim these effects with more reliability.

In my practice, I have observed that halim seeds may exhibit significant antidiarrheal properties. It is believed to achieve this by inhibiting gastrointestinal propulsion and fluid secretion, resulting in a decreased frequency of bowel movements and reduced fluid loss.

Dr. Rajeev Singh, BAMS

Other Potential Uses of Halim Seeds

Though there are studies that show the benefits of Halim seeds in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of Halim seeds on human health.  

How to Use Halim Seeds?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an Ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Halim Seeds

According to a study9, it is stated that in addition to the nutritional components, Halim seeds also contain anti-nutrients like phytates and oxalates, which may interfere with the absorption of nutrients.  

However, if you experience any adverse reactions to Halim seeds, it is advised to discontinue their intake and immediately contact a doctor or your Ayurvedic physician who has prescribed them. They will be able to guide you appropriately.

Also Read: Kayam Churna: Uses, Benefits, Side Effects and More

Precautions to Take with Halim Seeds

Consuming Halim seeds is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions8

The safety data regarding the use of Halim seeds in pregnant and breastfeeding women, the elderly and infants is limited; therefore, it is advised to take necessary cautions if you plan to add this herb to your dietary routine. It is advised to follow precautions and consume it in moderate amounts. 

Consuming Halim seeds is contraindicated in the following situations: 

Also Read: 14 Amazing Health Benefits of Pumpkin Seeds!

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Halim seeds with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking8.

Also Read: Chia Seeds: Uses, Benefits, Side Effects, and More!

Frequently Asked Questions (FAQs)

Can you use halim seeds for weight loss? 

Yes, animal studies3 show that Halim seeds may help in weight loss. However, we need more studies to support these claims in humans. Therefore, it is advised to consult a doctor for proper treatment in case you have any weight-related issues.

Can Halim seeds be used during pregnancy? 

The safety data regarding the use of Halim seeds in pregnancy is limited; therefore, it is advised to take necessary cautions if you plan to add this herb to your dietary routine. It is advised to consult a doctor for proper advice. 

Can Halim seeds be used to manage anaemia? 

Yes, Halim seeds, due to their high iron content, may help in managing iron-deficiency anemia. 

References

  1. Dixit Jr Iii, Vinti et al. “Lepidium sativum: Bone healer in traditional medicine, an experimental validation study in rats.” Journal of family medicine and primary care vol. 9,2 812-818. 28 Feb. 2020, doi:10.4103/jfmpc.jfmpc_761_19. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113932/ 
  2. AL Sayed et al. Utilization of garden cress seeds (lepidium sativum L.) as natural source of protein ‎and dietary fiber in noodles – pharmaceutical research and Allied Sciences. Available at: https://ijpras.com/article/utilization-of-garden-cress-seeds-lepidium-sativum-l-as-natural-source-of-protein-and-dietary-fiber-in-noodles (Accessed: December 13, 2022).  
  3. Azene, M., Habte, K. & Tkuwab, H. Nutritional, health benefits and toxicity of underutilized garden cress seeds and its functional food products: a review. Food Prod Process and Nutr 4, 33 (2022). Available at: https://doi.org/10.1186/s43014-022-00114-z.  
  4. Qusti, Safaa et al. “The Hypoglycemic and Antioxidant Activity of Cress Seed and Cinnamon on Streptozotocin Induced Diabetes in Male Rats.” Evidence-based complementary and alternative medicine : eCAM vol. 2016 (2016): 5614564. doi:10.1155/2016/5614564. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972928/ 
  5. Mahassni, Sawsan Hassan, and Roaa Mahdi Al-Reemi. “Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seeds.” Saudi journal of biological sciences vol. 20,2 (2013): 131-9. doi:10.1016/j.sjbs.2012.12.002. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730895/ 
  6. El-Gindy, Yassmine M et al. “Reproductive performance and milk yield of rabbits fed diets supplemented with garden cress (Lepidium sativum) seed.” Scientific reports vol. 12,1 17083. 12 Oct. 2022, doi:10.1038/s41598-022-21449-0. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556594/ 
  7. Jain, T., Grover, K. A Comprehensive Review on the Nutritional and Nutraceutical Aspects of Garden Cress (Lepidium sativum Linn.). Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci. 88, 829–836 (2018). Available at: https://doi.org/10.1007/s40011-016-0775-2 
  8. Lippert A, Renner B. Herb-drug interaction in inflammatory diseases: review of phytomedicine and herbal supplements. J Clin Med. 2022 Mar 12;11(6):1567. doi: 10.3390/jcm11061567. PMID: 35329893; PMCID: PMC8951360. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8951360/
  9. Malhotra U, Sontakke M, Shams R, Pandey VK. Effects of pre-treatments on nutritional and mineral composition of garden cress seeds (Lepidium sativum). Food Chem Adv. 2023;3(4):100398. doi:10.1016/j.focha.2023.100398. Available from: https://www.researchgate.net/publication/372523403_Effects_of_pre-treatments_on_nutritional_and_mineral_composition_of_garden_cress_seeds_Lepidium_sativum

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Sadabahar (Periwinkle): Uses, Benefits, Side Effects and More By Dr. Rajeev Singh

Introduction

Sadabahar or sadaphuli is a small shrub bearing purple, pink, or white flowers throughout the year and hence called “Sadabahar”. Natively called “periwinkle” in English Catharanthus roseus originated in Madagascar. This ornamental plant is cultivated throughout tropical and subtropical areas. Nearly 12 species are identified, out of which two are popular ground covers (a plant that grows over an area of ground). All the species bear single flowers and have opposite leaves. When the flowers are plucked, they exude a milky juice. The flowers bloom in March or April. Alba variety has white flowers, Atropurpurea has purple flowers, and Alboplena bears white flowers. Periwinkle is a rich source of medicinal compounds, and you need to know how nature has encapsulated love and care for all of us with this amazingly beautiful plant. Let us read more about the various health benefits Sadabahar leaves has to offer1

Did you know?

Nutritional Value of Sadabahar

Sadabahar leaves and flower petals are rich in flavonoids, alkaloids, carbohydrates and phytochemicals like vincristine, vinblastine, vincardine, etc. The nutritional components of Sadabahar leaves are mentioned below: 

Nutritional value of Sadabahar leaves2 

The Sadabahar plant might act as a “diuretic.” Taking Sadabahar might make the body less effective at eliminating lithium. Lithium levels may rise as a result, which may have various side effects. I suggest if you are on lithium, see your doctor before consuming Sadabahar in any form. You might need to adjust your lithium dosage.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Sadabahar

Scientifically proven properties of Sadabahar include1

Potential Uses of Sadabahar for Overall Health

Some of the potential benefits of Sadabahar are described as under:  

1. Potential Uses of Sadabahar on Type-2 Diabetes

diabetes

Type-2 diabetes is a metabolic disorder characterized by derangements (abnormalities) in blood glucose levels, due to decreased insulin (a hormone that regulates blood glucose) response or insulin resistance. Nammi et al. conducted a study in 2003 to assess the effects of sadabahar leaf juice on diabetic rats. The findings of this study stated that sadabahar had an anti-diabetic effect, attributed to increased secretion of insulin from beta cells of the pancreas. This indicates that sadabahar leaves may help in managing diabetes. However, we need more studies to support these claims in humans3

2. Potential Uses of Sadabahar on Hypertension

hypertension

Hypertension is defined as systolic blood pressure >130 mm Hg and diastolic blood pressure>80 mm Hg. Sadabahar as an anti-hypertensive (causing a decrease in blood pressure) agent has been used in folklore medicine. Ara et al. conducted a study in 2009 in hypertensive rats fed sadabahar leaves extract. The results of this study supported the use of sadabahar to manage high blood pressure, indicating that it may positively impact blood pressure. However, we need more studies to ascertain these claims in humans4

3. Potential Uses of Sadabahar on Cognitive Function

brain

A literature review by Medina et al. In 2010 stated that sadabahar contains chemical compounds called alkaloids which are known to enhance cognitive function. This effect is attributed to the inhibition of an enzyme called phosphodiesterase enzyme. The inhibition of this enzyme increases the levels of bio-molecules known to regulate memory, learning, etc. This indicates that sadabahar can positively impact cognitive function5

4. Potential Uses of Sadabahar on Male Pattern Hair Loss

hair loss

Androgenic Alopecia, or male pattern hair loss in men and female pattern hair loss in women, is a patterned and progressive hair loss. A review by Justin et al. was conducted in 2017, stating sadabahar may help manage androgenic alopecia. However, the exact mechanism behind this is unknown, and we need more scientific studies to claim these effects in humans6

5. Potential Uses of Sadabahar on Cancer

cancer

Vinca alkaloids are medicinal compounds obtained from the Madagascar periwinkle plant or sadabahar. Vinblastine, an important Vinca alkaloid, has anti-tumour activity and is widely used to manage testicular cancers. Vinorelbine, another alkaloid from sadabahar, finds use for managing breast cancers and osteosarcoma (bone cancer cells). This indicates that sadabahar may help manage cancers. However, the potent anticancer Vinca alkaloids are fully processed, and safety and toxicity are tested before use. We do not promote the use of sadabahar flowers or leaves for managing cancers7

6. Other Potential Uses of Sadabahar

periwinkle

Though there are studies that show the benefits of Sadabahar in various conditions, but these are insufficient and there is a need for further studies to establish the true extent of the benefits of Sadabahar on human health.  

Alzheimer’s disease (AD), a neurodegenerative illness of the central nervous system, affects 50–60% of people with dementia. It is distinguished by significant memory loss, emotional instability, and personality changes in later life. Studies have shown that the extracts of Sadabahar may aid in Alzheimer’s Disease as it has the potential to stimulate the nervous system. I suggest the consumption of Sadabahar with a doctor’s guidance and avoiding self-medication at all costs.

Dr. Rajeev Singh, BAMS

How to Use Sadabahar?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Sadabahar

A few side effects related to the consumption of sadabahar include: 

However, if you experience any adverse reactions to Sadabahar, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Also Read: Shankhpushpi: Benefits, Side Effects, Precautions & More!

Precautions to Take with Sadabahar

Consuming Sadabahar is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions: 

Also Read: Sandalwood: Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of sadabahar with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking3,9

Also Read: Chitrakadi Vati: Uses, Benefits, Side Effects & More!

Frequently Asked Questions (FAQs)

What is the scientific name of sadabahar? 

The scientific name of sadabahar is Catharanthus roseus1

What are the varieties of sadabahar available in the market? 

Depending on the colour of the flower, two-three varieties are known, these include Alba variety which has white flowers, Atropurpurea which has purple flowers and Alboplena bears white flowers1

Can sadabahar help manage diabetes?  

Yes, animal studies show that sadabahar has an anti-diabetic effect, attributed to increased secretion of insulin (a hormone that regulates blood glucose) from beta cells of the pancreas.  However, we need more studies to support these claims in humans. Therefore, it is advised to consult a doctor for a proper treatment in case you suffer from diabetes3

Can sadabahar be used in pregnancy? 

The safety data regarding the use of sadabahar in pregnancy and during breastfeeding is limited; therefore it is advised to take necessary cautions if you plan to add this herb to your dietary routine. It is advised to consult a doctor for proper advice11

What are the side effects of sadabahar? 

Loh et al. in 2008 stated that vincristine, an alkaloid derived from sadabahar can cause hair loss, constipation, hyponatremia (low sodium levels in the body) and peripheral neuropathy (nerve damage resulting in pain, weakness, etc). Additionally, the consumption of sadabahar petals or leaves in excess can result in unwanted effects like nausea, vomiting, headache and fever10

References

  1. Dr. Anita Kale. (2021). A scientific review on Sadaphuli in Ayurveda. Journal of Ayurveda and Integrated Medical Sciences, 6(3), 94 – 99. Retrieved from https://www.jaims.in/jaims/article/view/1309 
  1. Radali, Duarah & Gupta, Alka. (2018). Periwinkle (Catharanthus roseus) Leaves and Lemongrass (Cympoogon citratus): An Analysis of Their Nutritional Composition, Anti-Nutritional Factors and Antioxidant Content. International Journal of Current Microbiology and Applied Sciences. 7. 2130-2135. 10.20546/ijcmas.2018.706.253. Available at: https://www.researchgate.net/publication/326643359_Periwinkle_Catharanthus_roseus_Leaves_and_Lemongrass_Cympoogon_citratus_An_Analysis_of_Their_Nutritional_Composition_Anti-Nutritional_Factors_and_Antioxidant_Content 
  1. Nammi, Srinivas et al. “The juice of fresh leaves of Catharanthus roseus Linn. reduces blood glucose in normal and alloxan diabetic rabbits.” BMC complementary and alternative medicine vol. 3 (2003): 4. doi:10.1186/1472-6882-3-4. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194756/pdf/1472-6882-3-4.pdf 
  1. Ara, Naznin et al. “Comparison of hypotensive and hypolipidemic effects of Catharanthus roseus leaves extract with atenolol on adrenaline induced hypertensive rats.” Pakistan journal of pharmaceutical sciencesvol. 22,3 (2009): 267-71. Available at: https://pubmed.ncbi.nlm.nih.gov/19553172/ 
  1. Medina, Alexandre E. “Vinpocetine as a potent antiinflammatory agent.” Proceedings of the National Academy of Sciences of the United States of Americavol. 107, 22 (2010): 9921-2. doi:10.1073/pnas.1005138107. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890434/ 
  1. Tan, Justin J Y et al. “Bioactives in Chinese Proprietary Medicine Modulates 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia.” Frontiers in pharmacology vol. 8 194. 13 Apr. 2017, doi:10.3389/fphar.2017.00194. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5390023/
  1. Moudi, Maryam et al. “Vinca alkaloids.” International journal of preventive medicine vol. 4,11 (2013): 1231-5. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883245/ 
  2. Periwinkle. Available at: https://www.organicindiausa.com/blog/benefits-of-madagascar-periwinkle/
  3. Dey, S. (2017) Periwinkle: A herbal powerhouse, Side Effects & DosageHealthXP. Available at: https://healthxp.in/periwinkle-a-herbal-powerhouse-side-effects-dosage/ (Accessed: December 12, 2022).  
  4. Nejat, Naghmeh et al. “Ornamental exterior versus therapeutic interior of Madagascar periwinkle (Catharanthus roseus): the two faces of a versatile herb.” TheScientificWorldJournal vol. 2015 (2015): 982412. doi:10.1155/2015/982412. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312627/ 
  5. Loh, Ky. “Know the Medicinal Herb: Catharanthus roseus (Vinca rosea).” Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia vol. 3,2 123. 31 Aug. 2008. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170313/ 
  6. Periwinkle (pink or white) (catharanthus roseus): Queensland Poisons Information Centre (2017) Children’s Health Queensland. Available at: https://www.childrens.health.qld.gov.au/poisonous-plant-pink-white-periwinkle-catharanthus-roseus/ (Accessed: December 16, 2022).  

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Ashoka Tree: Uses, Benefits, Side Effects and More!

Introduction

You would come across an Ashoka tree while walking in your building compound or on the streets. The Ashoka tree is considered sacred and legendary in India. In Sanskrit, Asoka or Ashoka means ‘without sorrow’. Ashoka is associated with several traditional beliefs and is sacred to the Hindu God of love, Kamadeva. It is believed that Gautama Siddhartha, the founder of Buddhism, was born under the Ashoka tree. The scientific name of the Ashoka tree is Saraca asoca, which belongs to the Caesalpinaceae family. Ashoka tree is native to India and is found all over India, especially in the Himalayas, Kerala, Bengal and the southern regions. The Ashoka tree has been used extensively in Ayurveda1. Let us look at some of the health benefits of the Ashoka tree. 

Nutritional Value of Ashoka Tree

Ashoka plants may contain several bioactive compounds like saponins, steroids, proteins, carbohydrates, tannins, glycosides, flavonoids, and many more1. Ashoka tree leaves and flowers may contain the following components: 

Did you know that in Sri Lanka, the traditional medicine called Asokaristha is used to tackle menstrual disorders like menorrhagia? The key component of this medicinal preparation is the bark of the Ashoka tree. However, additional studies have been conducted to understand the scientific basis behind its effectiveness10.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Ashoka Tree

Several studies have shown that the Ashoka tree may have the following properties: 

Did you know that the bark of the Ashoka tree might aid various conditions like indigestion, dysentery, piles, irregular menstruation, and sores? And guess what? The dried flowers of the tree may be used in syphilis and haemorrhage11!

Dr. Rajeev Singh, BAMS

Potential Uses of Ashoka Tree for Overall Health

Some of the potential Ashoka tree uses are: 

1. Potential Use of Ashoka Tree for Cancer

A study3 by Cibin et al. in 2012 showed that flavonoids from Ashoka tree flowers might reduce the number of tumours in skin cancer. This is because it may destabilise the free radicals (harmful molecules in the body) and reduce oxidative degradation of lipids (fats). Additionally, flavonoids from the Ashoka tree may reduce the enzymes like glutathione peroxide, catalase and ornithine decarboxylase, which may be responsible for causing skin cancer. However, these studies were conducted on animals; therefore, further studies on humans are required to check if the Ashoka tree can act against cancer. You must immediately consult your doctor if you suspect any symptoms of cancer. 

2. Potential Use of Ashoka Tree for Bacterial Infections

A study2 by Shirolkar et al. in 2012 showed that catechins in Ashoka tree bark and leaves might show antimicrobial activity. The catechins may inhibit the growth of bacteria. It may act against infections caused by bacteria like E. coli, Pseudomonas aeruginosa, Staphylococcus aureas, and many more. However, further studies are required to check if the Ashoka tree may be beneficial for bacterial infections. Therefore, you must consult your doctor if you suspect any bacterial infection. 

3. Potential Use of Ashoka Tree for Heart Diseases

A study5 by Swamy et al. in 2013 showed that bioactive compounds like β-sitosterol and epicatechin in the Ashoka tree might reduce the risk of heart disease. Ashoka tree may reduce bad cholesterol levels by destabilizing the body’s free radicals (harmful molecules) and reduce oxidative degradation of lipids (fats). High cholesterol levels in the body may increase the risk of heart diseases; therefore, antioxidant activity may contribute to protecting the heart. However, further large-scale studies on humans are required to investigate if the Ashoka tree may be beneficial in reducing the risk of heart diseases. Therefore, you must immediately consult your doctor if you suspect any symptoms of heart disease. 

4. Potential Use of Ashoka Tree for Arthritis

A study4 by Gupta et al. in 2014 showed that the flavonoids like quercetin and gallic acid in the Ashoka tree may reduce inflammation caused in arthritis. The inflammation may be reduced by inhibiting the release of inflammatory cytokines (molecules in the body responsible for causing inflammation).  However, further studies are required to check if the Ashoka tree may be beneficial for arthritis. Therefore, you must consult your doctor if you suspect arthritis instead of self-medicating. 

5. Potential Use of Ashoka Tree for Stomach Ulcers

A study6 by Maruthappan et al. in 2009 showed that flowers of the Ashoka tree might help to reduce stomach ulcers. The results suggested that the Ashoka tree may reduce lesions, inflammation and acid secretion to reduce stomach ulcers. However, these studies were conducted on animals; therefore, further large-scale studies on humans are required to check if the Ashoka tree may be beneficial for stomach ulcers. You must consult your doctor if you suspect ulcers. 

6. Potential Use of Ashoka Tree for Diabetes

A study7 by Mishra et al. in 2014 showed that bioactive compounds like phytosterol, flavonoids and saponins in the Ashoka tree might be beneficial for type II diabetes. These bioactive compounds may increase the secretion of insulin (a hormone that regulates blood sugar levels). Additionally, it may reduce blood sugar levels. However, further large-scale studies on humans are required to check if the Ashoka tree may be beneficial for diabetes. You must consult your doctor if you have abnormal sugar levels. 

7. Potential Use of Ashoka Tree for Reducing Pain

A study by Verma et al. in 2010 showed that intake of leaf extracts of the Ashoka tree may help to relieve pain. The bioactive compounds like tannins, triterpenoids, saponin, flavonoids and glycosides in the Ashoka tree might help to reduce pain. However, further studies are required to check if the Ashoka tree may be beneficial in reducing pain. Therefore, you must consult your doctor if you experience pain for a prolonged period. 

8. Potential Use of Ashoka Tree for Depression

A study9 by Gill et al. in 2017 showed that flavonoids and phenols in the Ashoka tree might help to reduce depression. These bioactive compounds may increase the antioxidants in the brain and reduce oxidative stress by destabilizing harmful free radicals. This may reduce the symptoms of depression. However, further large-scale studies on humans are required to check if the Ashoka tree may be beneficial for depression. Therefore, you must consult a doctor if you suspect symptoms of depression. 

Though studies show the benefits of the Ashoka tree in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of the Ashoka tree on human health. 

It’s interesting to note that the Ashoka tree might be beneficial in detoxifying the body and naturally purifying the blood. This may help to keep skin allergies away. It’s amazing how this natural remedy offers multiple benefits for overall well-being11!

Dr. Smita barode, B.A.M.S, M.S.

How to Use Ashoka Tree?

Various parts of the Ashoka tree can be consumed in the following ways1

You must consult a qualified doctor before taking Ashoka tree in large quantities or any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor. 

Did you know that the Ashoka tree is like a superhero for your skin? Its root, bark, and seed extracts may have incredible powers to tackle a wide range of skin issues! From fighting off acne and eczema to reducing freckles and even enhancing skin complexion, this tree with its various parts might be a true skin saviour12.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

Side Effects of Ashoka Tree

Various natural preparations made from parts of the Ashoka tree has no specific side effects. However, if any reaction is noticed on using it, seek immediate medical attention. Consult your ayurvedic physician who has prescribed it to you; they will be able to identify the cause and treat it effectively. 

Also Read: Shilajit: Uses, Benefits & Side Effects By Dr. Anuja Bodhare

Precautions to Take with Ashoka Tree

The following precautions must be taken before consuming the Ashoka tree: 

It is advised to consult your doctor before consuming a preparation made from parts of the Ashoka tree if you have any pre-existing diseases. 

The Ashoka herb has special benefits for the endometrium (lining of the uterus) and uterine muscles. This might make it a helpful uterine tonic for addressing irregular menstrual cycles and avoiding miscarriages.

Dr. Ashok Pal, BAMS

Interactions with Other Drugs

There is not enough evidence on the interaction of the Ashoka tree with other drugs. Further studies on the interaction of the Ashoka tree are required. Therefore, you must consult your doctor if you are on any other medication before consuming Ashoka tree. 

Also Read: Atibala: Benefits, Side Effects, Precautions & More

Frequently Asked Questions (FAQs)

What are the Ashoka tree medicinal uses? 

There are several medicinal uses of Ashoka tree. Ashoka tree may act against cancer. It may be used for bacterial infections, arthritis, ulcers and depression. Ashoka tree may protect the heart and help to reduce blood sugar levels. Additionally, the Ashoka tree may help to relieve pain. However, you must consult your doctor if you experience symptoms of the mentioned conditions instead of self-medicating. 

How do you consume different parts of the Ashoka tree? 

Various parts of the Ashoka tree can be consumed. The bark of the Ashoka tree can be powdered and consumed with honey. The decoction of the bark of the Ashoka tree can be consumed with milk. Ashoka tree can be consumed as ayurvedic medicines in the form of Asokarishta and Asokaghrita. However, you must consult a qualified doctor before using such preparations. 

What precautions should be taken before consuming any part of the Ashoka tree? 

Pregnant and breastfeeding women should be careful before consuming any parts of the Ashoka tree. People with heart disease should also be careful before consuming any parts of the Ashoka tree. You should consult a doctor before consuming the leaf or flower of the Ashoka tree if you have any pre-existing diseases. 

What are the side effects of consuming a part of the Ashoka tree? 

Various natural preparations made from parts of the Ashoka tree have no specific side effects. However, if any reaction is noticed on using it, seek immediate medical attention. Consult your ayurvedic physician who has prescribed it to you; they will be able to identify the cause and treat it effectively. 

What is the nutritional value of the Ashoka tree?


Ashoka leaves and flowers may contain bioactive compounds like tannins, steroids, proteins, carbohydrates, saponins, glycosides, flavonoids and many more. 

References

  1. Athiralakshmy TR, Divyamol AS, Nisha P. Phytochemical screening of Saraca asoca and antimicrobial activity against bacterial species. Asian Journal of Plant Science and Research. 2016;6(2):30-6. Available from: https://www.imedpub.com/articles-pdfs/phytochemical-screening-of-saraca-asoca-and-antimicrobial-activity-against-bacterial-species.pdf 
  2. Shirolkar A, Gahlaut A, Chhillar AK, Dabur R. Quantitative analysis of catechins in Saraca asoca and correlation with antimicrobial activity. Journal of Pharmaceutical Analysis. 2013 Dec 1;3(6):421-8. Available from: https://www.sciencedirect.com/science/article/pii/S2095177913000117 
  3. Sharma M, Sharma A, Soni A, et al. Chemoprevention of skin cancer by the flavonoid fraction of Saraca asoka. J Dermatol Sci. 2009;55(3):226-34. Available from: https://www.researchgate.net/publication/26677759_Chemoprevention_of_Skin_Cancer_by_the_Flavonoid_Fraction_of_Saraca_asoka#:~:text=and%20fatty%20acids.-,…,6).%20…
  4. Ghatak A, Nair S, Vajpayee A. Evaluation of antioxidant activity, total phenolic content, total flavonoids, and LC-MS characterization of Saraca asoca (Roxb.) De.Wilde. Int J Adv Res. 2015;3(5):318-27. Available from: https://www.researchgate.net/publication/277477244_Evaluation_of_antioxidant_activity_total_phenolic_content_total_flavonoids_and_LC-MS_characterization_of_Saraca_asoca_Roxb_DeWilde
  5. Prasad S, Younis K, Yousuf O. Investigating potent cardioprotective compounds as ACE inhibitors in Saraca asoca. Toxicol Rep. 2024 Sep 10;13:101731. doi: 10.1016/j.toxrep.2024.101731. PMID: 39309635; PMCID: PMC11416659. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11416659/
  6. Mohan C, Kistamma S, Vani P, Reddy AN. Biological activities of different parts of Saraca asoca, an endangered valuable medicinal plant. Int J Curr Microbiol App Sci. 2016;5(3):269-276. Available from: https://www.ijcmas.com/5-3-2016/Ch.%20Mohan,%20et%20al.pdf
  7. Tran N, Pham B, Le L. Bioactive Compounds in Anti-Diabetic Plants: From Herbal Medicine to Modern Drug Discovery. Biology (Basel). 2020 Aug 28;9(9):252. doi: 10.3390/biology9090252. PMID: 32872226; PMCID: PMC7563488. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7563488/
  8. Ghosh A, Saha A, Ghosh D, et al. Analgesic activity of various leaf extracts of Saraca indica Linn. Pharmacognosy Res. 2014;6(2):107-10. Available from: https://www.researchgate.net/publication/256547569_Analgesic_Activity_of_Various_Leaf_Extracts_of_Saraca_indica_Linn#:~:text=Citations%20(14)-,References%20(15),%2C%202014).%20…
  9. Ahmad SR, Ghosh P. A systematic investigation on flavonoids, catechin, β‑sitosterol and lignin glycosides from Saraca asoca (ashoka) having anti‑cancer & antioxidant properties with no side effect. J Indian Chem Soc. 2021;99:100293. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0019452221002934#:~:text=Numerous%20antioxidant%20compounds%20like%20flavonoids%2C%20catechin%2C%20beta%2Dsitosterol%2C,associated%20with%20the%20development%20of%20cancer%20conditions.
  10. Middelkoop TB, Labadie RP. The action of Saraca asoca Roxb. de Wilde bark on the PGH2 synthetase enzyme complex of the sheep vesicular gland. Z Naturforsch C Biosci. 1985 Jul-Aug;40(7-8):523-6. doi: 10.1515/znc-1985-7-812. PMID: 3931371. Available from: https://pubmed.ncbi.nlm.nih.gov/3931371/
  11. Smitha GR, Thondaiman V. Reproductive biology and breeding system of Saraca asoca (Roxb.) De Wilde: a vulnerable medicinal plant. Springerplus. 2016 Nov 28;5(1):2025. doi: 10.1186/s40064-016-3709-9. PMID: 27995002; PMCID: PMC5125291. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5125291/
  12. Nyeem MA, Haque MS, Haq MO, Nuruzzaman M, Uddin H, Islam R. Ashoka (Saraca indica) as women friendly plant: A review. Natl J Adv Res. 2017;3(2):03‑07. Available from: https://www.researchgate.net/publication/355955294_Ashoka_Saraca_indica_as_women_friendly_plant_A_review

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Rambutan: Uses, Benefits, Side Effects, and More By Dr. Smita Barode

Introduction

Rambutan is a fascinating looking red spiky fruit with soft thorns in red, yellow, and green shades. It is also known as a hairy fruit. It is a tropical, ovoid shaped fruit with a red or yellow fruit wall. The Rambutan tree is originally from Malaysia, and its name is derived from the Malay word ‘rambut’ which means hair. Rambutan is popularly grown in India, Malaysia, Indonesia, Thailand, and some humid parts of the United States. The scientific name of rambutan is Nephelium lappaceum, and it belongs to the family Sapindaceae. Rambutan pulp, seeds and peel have several bioactive compounds that may benefit food, pharmaceuticals, medicine, and cosmetics advances1. Let us glance through some of the benefits of eating rambutan and experience the unique rambutan taste, characterized by its sweet and juicy profile with hints of floral notes.

Nutritional Value of Rambutan

Rambutan seeds, peel and pulp may contain several bioactive compounds like polyphenols, including ellagitannins, geraniin, corilagin, and ellagic acid. It may contain fatty acids like arachidonic acid, stearic acid, palmitic acid and many more1. Furthermore, Rambutan fruit may contain the following nutrients: 

Did you know?

Properties of Rambutan

Several studies have shown that rambutan may have the following properties: 

Rambutan seeds are roasted and eaten as snacks in the Philippines. Munching on these seeds as a morning or evening snack not only satisfies your taste buds but also offers rambutan benefits for health and well-being14.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Benefits of Rambutan For Overall Health

Some of the potential rambutan benefits are: 

1. Potential Benefits of Rambutan as an Antioxidant

Rambutan

A study3 by Hernàndez et al. in 2017 showed that rambutan might be an antioxidant. The antioxidant potential of rambutan may be due to phytochemical compounds like phenols, flavonoids, corilagin, geraniin, and ellagic acid. These compounds may deactivate the free radicals (harmful molecules present in the body) and protect the body from various damages. 

2. Potential Benefits of Rambutan for Cancer

cancer

A study by Perumal et al. in 2020 showed that rambutan might act against breast, bone, cervical and liver cancer. The anticancer activity of rambutan may be due to bioactive compounds like flavonoids, alkaloids, tannins, terpenoids and other phenolic compounds like geraniin. Rambutan benefits may show apoptosis (kill the cancer cells) and inhibit their growth. However more studies are required to check if rambutan can be used against cancer. Cancer is a serious disease therefore, you must consult your doctor if you suspect cancer instead of self-medicating. 

3. Potential Benefits of Rambutan for Reducing Sugar Levels

regulates blood sugar

Rambutan is a delicious tropical fruit that might offer potential benefits for diabetes management. A study by Muhtadi et al. in 2016, conducted on rats, suggested that bioactive compounds found in rambutan, such as catechin, quercetin, polyphenols, geraniin, and tannins, could contribute to reducing blood sugar levels. These compounds may help inhibit glucose absorption by the cells and stimulate insulin secretion, potentially assisting in the maintenance of normal blood sugar levels. It’s important to note that this study was conducted on animals, and further research on humans is needed to confirm the potential rambutan benefits for diabetes. If you have diabetes it’s essential to monitor your blood sugar levels regularly and consult with your healthcare provider for appropriate guidance.

4. Potential Benefits of Rambutan for Dengue

mosquito

A study6 by Ahmad et al. in 2015 showed that geraniin in rambutan might have anti-viral activity and act against DENV-2 (dengue virus type-2). Geraniin may inhibit the attachment of the dengue virus to the body cells and may also interfere with a viral protein (E protein) to disrupt the infection process. However, further studies are required to check if rambutan may act against the dengue virus. Therefore you must immediately consult your doctor if you suspect any symptoms of dengue. 

5. Potential Benefits of Rambutan to Reduce Inflammation

reduces inflammation

A study7 by Chingsuwanrote et al. in 2015 showed that the polyphenols in rambutan might reduce inflammation. The polyphenols may inhibit the secretion of TNFα, an inflammatory cytokine (molecules in the body responsible for inflammation). However, more studies are required to check if rambutan has anti-inflammatory properties. 

6. Potential Benefits of Rambutan for Bacterial Infections

infection

A study8 by Phuong et al. in 2020 showed that bioactive compounds in rambutan, like tannins, corilagin, geraniins, and ellagic acid, may possess antibacterial activity. Various bioactive compounds have different ways of showing their antibacterial activity. Tannins may change the structure of the cell wall and cell membrane. Ellagic acid may attach to the cell wall and destabilize it. Corilagin may inhibit the growth of bacteria by disrupting cell permeability. However, more large scale studies are required to check the antibacterial effect of rambutan. Therefore you must consult your doctor if you suspect a microbial infection. 

7. Potential Benefits of Rambutan for Controlling Blood Pressure

A study9 by Fang et al in 2018 suggested that rambutan fruit benefits might extend to lowering blood pressure. Specifically, geraniin found in rambutan may play a role in reducing blood pressure by decreasing the release of noradrenaline (a hormone that increases blood pressure) and relaxing tension in the blood vessels. Further research involving human subjects is needed to confirm these effects. It’s essential to consult your doctor if you have abnormal blood pressure instead of attempting self-medication.

Though studies show the benefits of rambutan in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of rambutan on human health. 

Researchers are evaluating the anti-HIV, anti-dengue and anti-allergic properties of Rambutan. These activities have been observed during lab trials more research is needed to support these claims14.

Dr. Rajeev Singh, BAMS

How to Use Rambutan?

Rambutan can be consumed in the following way: 

You must consult a qualified doctor before taking large quantities of Rambutan or other herbal supplements. Likewise, do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor. 

Side Effects of Rambutan

Rambutan side effects are reported as follows: 

If you notice any reaction by consuming rambutan, seek immediate medical attention. First, consult your ayurvedic physician who has prescribed it to you; they will be able to identify the cause and treat it. 

Precautions to Take with Rambutan

The following precautions can be taken before consuming rambutan: 

It is advised to consult your doctor before consuming if you have any pre-existing diseases. 

Conclusion

There is not enough evidence on the interaction of rambutan with other drugs. Further studies on the interaction of rambutan are required. Therefore you must consult your doctor if you are on any other medication before consuming rambutan. 

Also Read: Nirgundi: Benefits, Uses, Side Effects & More!

Frequently Asked Questions (FAQs)

What are Rambutan fruit side effects? 

Rambutan may cause nausea and vomiting, angioedema (swelling of the lower layer of skin), urticaria (swollen, reddened, and itchy skin), flushing of the skin (sudden redness of the skin), chest tightness, and wheezing11

Is Rambutan good for diabetes? 

Bioactive compounds in rambutan, like catechin, quercetin, polyphenols, geraniin, and tannins, may help to reduce blood sugar5. However, you must check your blood sugar levels regularly and consult your doctor in case of abnormal blood sugar levels

What precautions must be taken with Rambutan?

Rambutan is considered safe, but pregnant and breastfeeding mothers shall take precautions before consuming rambutan12. Saponins and tannins are phytochemicals, and they are biologically active compounds. But in a few cases, saponins and tannins may be toxic to a few people. In addition, rambutan seeds may be narcotic (causes sleepiness and affects mood)13. It is advised to consult your doctor if you have any pre-existing diseases before consuming. 

Can Rambutan seeds be eaten?

Rambutan seeds are generally not recommended for consumption as they can be bitter and potentially toxic. It’s advisable to consult with a healthcare professional for personalized guidance regarding your dietary choices and potential risks associated with consuming rambutan seeds.

Can Rambutan cause sore throat?

While rambutan consumption is not commonly associated with sore throat, individual reactions may vary. If you experience a sore throat after consuming rambutan or suspect any adverse reactions, it’s advisable to consult with a healthcare professional for a personalized assessment and guidance.

Can Rambutan make you sick?

Consuming rambutan is generally safe for most individuals. However, if you experience digestive discomfort, allergies, or any adverse reactions after consuming rambutan, it’s advisable to consult with a healthcare professional for a proper assessment and personalized guidance to determine the cause of the illness.

Can Rambutan increase uric acid?

Rambutan is not a known food source that significantly increases uric acid levels. However, individual reactions can vary, and those with gout or uric acid concerns should consume it in moderation and monitor their own body’s response. If you have specific health concerns, consulting a healthcare professional is advisable for personalized guidance.

Are Rambutans good for dogs?

Rambutan should be avoided for dogs as it can pose a choking hazard due to its large seed and may not provide significant nutritional benefits for them. It’s best to consult with a veterinarian for guidance on safe and appropriate treats for your pet.

Can Rambutan cause stomach pain?

Rambutan is typically safe to eat, but for some individuals, overconsumption or sensitivity to certain compounds in the fruit might lead to stomach discomfort or pain. If you experience stomach pain after consuming rambutan, consult a healthcare professional to rule out any allergies or sensitivities and to ensure it aligns with your dietary choices.

Can Rambutan cause constipation?

While rambutan is generally not associated with causing constipation, excessive consumption or dietary factors could potentially lead to this issue in some individuals. If you encounter constipation after eating rambutan, consult a healthcare professional to assess your dietary choices and address any underlying causes.

Can Rambutan cause acne?

Rambutan is not commonly linked to causing acne. However, an individual’s skin reactions can vary, and it’s possible that consuming rambutan, especially in excessive amounts, might lead to skin issues for some people. Consulting a healthcare professional or dermatologist can help identify any specific triggers and address potential skin concerns.

Can Rambutan cause cough?

Rambutan is not a known cause of cough. Coughing can result from various factors such as infections, allergies, or irritants. If you experience persistent coughing after consuming rambutan, consult a healthcare professional to rule out any allergies or underlying respiratory issues.

Can Rambutan cause miscarriage?

There is no scientific evidence to suggest that rambutan can cause a miscarriage. However, during pregnancy, it’s crucial to be cautious about your dietary choices and consult a healthcare professional for guidance on safe and healthy eating practices to support a healthy pregnancy.

Can Rambutan cause diarrhea?

Rambutan consumption is generally safe, but excessive intake may lead to diarrhea in some individuals due to its natural sugars and dietary fiber. If you experience persistent or severe diarrhea after eating rambutan, consult a healthcare professional to assess any underlying issues and ensure proper hydration and dietary choices.

How to eat Rambutan?

To eat rambutan, start by making a shallow cut around the circumference of the fruit’s skin, being careful not to cut too deep. Then, gently twist the fruit open, revealing the juicy flesh inside. Remove the seed and enjoy the sweet and slightly tangy fruit.

Is Rambutan a tree nut?

No, rambutan is not a tree nut. It is a tropical fruit belonging to the Sapindaceae family and is botanically related to lychee and longan. While it may trigger allergies in some individuals, it is not classified as a tree nut allergen.

References

  1. Hernández-Hernández C, Aguilar CN, Rodríguez-Herrera R, Flores-Gallegos AC, Morlett-Chávez J, Govea-Salas M, Ascacio-Valdés JA. Rambutan (Nephelium lappaceum L.): Nutritional and functional properties. Trends in food science & technology. 2019 Mar 1;85:201-10. Available from: https://www.researchgate.net/publication/391314241_Antiviral_Activity_of_Rambutan_Peel_Polyphenols_Obtained_Using_Green_Extraction_Technology_and_Solvents
  2. Rambutan, canned, syrup pack [Internet]. FoodData Central. [cited 2022Dec1]. Available from: https://fdc.nal.usda.gov/fdc-app.html#/food-details/168167/nutrients 
  3. Hernández C, Ascacio-Valdés J, De la Garza H, Wong-Paz J, Aguilar CN, Martínez-Ávila GC, Castro-López C, Aguilera-Carbó A. Polyphenolic content, in vitro antioxidant activity and chemical composition of extract from Nephelium lappaceum L.(Mexican rambutan) husk. Asian Pacific Journal of Tropical Medicine. 2017 Dec 1;10(12):1201-5. Available from: https://www.sciencedirect.com/science/article/pii/S1995764517311641 
  4. Perumal A, AlSalhi MS, Kanakarajan S, Devanesan S, Selvaraj R, Tamizhazhagan V. Phytochemical evaluation and anticancer activity of rambutan (Nephelium lappaceum) fruit endocarp extracts against human hepatocellular carcinoma (HepG-2) cells. Saudi Journal of Biological Sciences. 2021 Mar 1;28(3):1816-25. Available from: https://www.sciencedirect.com/science/article/pii/S1319562X2030680X 
  5. Muhtadi M, Haryoto H, Sujono TA, Suhendi A. Antidiabetic and antihypercholesterolemia activities of rambutan (Nephelium lappaceum L.) and durian (Durio zibethinus Murr.) fruit peel extracts. Journal of Applied Pharmaceutical Science. 2016 Apr 30;6(4):190-4. Available from: https://japsonline.com/admin/php/uploads/1848_pdf.pdf 
  6. Ahmad SA, Palanisamy U, Tejo BA, Hassan SS. Geraniin extracted from the Nephelium lappaceum (rambutan) rind inhibits dengue virus type-2. International conference and expo on drug discovery and designing, Frankfurt 2015. Available from: https://www.longdom.org/conference-abstracts-files/2169-0138.S1.008-024.pdf 
  7. Chingsuwanrote P, Muangnoi C, Parengam K, Tuntipopipat S. Antioxidant and anti-inflammatory activities of durian and rambutan pulp extract. International Food Research Journal. 2016 Aug 1;23(3). Available from: http://www.ifrj.upm.edu.my/23%20(03)%202016/(5).pdf 
  8. Phuong NN, Le TT, Van Camp J, Raes K. Evaluation of antimicrobial activity of rambutan (Nephelium lappaceum L.) peel extracts. International journal of food microbiology. 2020 May 16;321:108539. Available from: https://www.sciencedirect.com/science/article/pii/S0168160520300337 
  9. Phang SC, Palanisamy UD, Kadir KA. Effects of geraniin (rambutan rind extract) on blood pressure and metabolic parameters in rats fed high-fat diet. Journal of integrative medicine. 2019 Mar 1;17(2):100-6. Available from: https://www.sciencedirect.com/science/article/pii/S2095496419300081 
  10. Thulaja NR. Rambutan [Internet]. Infopedia. [cited 2022Dec1]. Available from: https://www.nlb.gov.sg/main/article-detail?cmsuuid=f5af61c8-6be6-4ec3-bc4e-d6a4c08c55b8
  11. Jirapongsananuruk O, Jirarattanasopa N, Pongpruksa S, Vichyanond P, Piboonpocanun S. Glyceraldehyde-3-phosphate dehydrogenase as a major allergen in rambutan-induced anaphylaxis. Annals of Allergy, Asthma & Immunology. 2011 Jun 1;106(6):545-7. Available from: https://www.annallergy.org/article/S1081-1206(11)00188-8/abstract 
  12. Diana R, Rachmayanti RD, Anwar F, Khomsan A, Christianti DF, Kusuma R. Food taboos and suggestions among Madurese pregnant women: a qualitative study. Journal of Ethnic Foods. 2018 Dec 1;5(4):246-53. Available from: https://www.sciencedirect.com/science/article/pii/S2352618118301446 
  13. Rambutan Nephelium lappaceum L. Euphoria nephelium DC. Dimocarpus crinita Lour. [Internet]. Rambutan. [cited 2022Dec2]. Available from: https://www.hort.purdue.edu/newcrop/morton/rambutan.html
  14. Afzaal M, Saeed F, Bibi M, Ejaz A, Shah YA, Faisal Z, Ateeq H, Akram N, Asghar A, Shah MA. Nutritional, pharmaceutical, and functional aspects of rambutan in industrial perspective: An updated review. Food Sci Nutr. 2023 Apr 19;11(7):3675-3685. doi: 10.1002/fsn3.3379. PMID: 37457167; PMCID: PMC10345721. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10345721/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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