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Ashwagandha: Uses, Benefits & Side Effects

By Dr Siddharth Gupta +2 more

Introduction

Ashwagandha (Withania somnifera) is a popular herb in the Ayurvedic system of medicine. It is a small shrub that belongs to the Solanaceae family. It might be useful for different diseases and mostly as a nervine tonic (has a soothing effect on nerves). Ashwagandha is commonly called Indian Ginseng or Indian winter cherry. Ashwagandha is known for its rasayana (tonic) property. Rasayana is a herbal or metallic formulation that stimulates a youthful physical and mental state of health as well as happiness1.

Ashwagandha is cultivated in dry regions of South Asia, Africa, and Central Asia. More than 50 chemical constituents have been isolated from different parts of the ashwagandha plant1.

ashwagandha benefits

Did you know?

  • Ashwagandha is rich in iron, providing approximately 17% of the recommended daily intake per serving. source: USDA FoodData Central
  • Ashwagandha may help improve sleep quality and reduce insomnia symptoms. source: NCCIH
  • Ashwagandha have potential benefits for male reproductive health, including increasing testosterone levels and improving sperm quality. source: NCCIH 
  • Ashwagandha contains a variety of beneficial compounds, including alkaloids, steroidal lactones, and withanolides. source: NCCIH 
  • Ashwagandha is also known for its adaptogenic and anti-stress properties, which may improve stamina and support adrenal health.  source: PMC

Nutritional Value of Ashwagandha

In 100 grams of ashwagandha, the nutrients found are:


  • Energy: 250 kcal
  • Total Dietary Fibre: 25 g
  • Carbohydrate: 75 g

Properties of Ashwagandha

The potential properties of ashwagandha are2:

  • It might help with pain relief and sleep
  • It may act as a diuretic (expelling urine from the body)
  • It may act as an astringent (constricting body tissues)
  • It may be an antihelminthic (acting against parasitic worms)
  • It may be thermogenic (heat-producing)1
  • It might have anti-inflammatory (reduces swelling) potential
  • It may be an antipyretic (reducing fever)
  • It may have depurative (detoxifying) properties1
  • It may be heart-protective
  • It might act as a sedative (inducing sleep)
  • It may be thyroprotective (protecting the thyroid gland)
  • It might have hypoglycaemic (blood sugar-lowering) properties3

Ashwagandha is also called an ‘adaptogenic’ herb or a ‘royal’ herb since it helps reduce stress and helps your body adapt to changes. It rejuvenates various body systems like the immune, reproductive and endocrine systems9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Ashwagandha

The potential uses of ashwagandha for human health are as follows:

1. Ashwagandha for Anxiety and Depression

Ashwagandha might have anxiolytic (anxiety-relieving) properties that are similar to that of the drug lorazepam. Both ashwagandha and lorazepam showed to help reduce anxiety in animal models. Ashwagandha might also exhibit potential antidepressant properties. This indicates that Ashwagandha might help with depression and anxiety1. However, more research is required. Anxiety and depression may need serious attention and one should seek medical help from a professional for it.


2. Ashwagandha for Arthritis

Ashwagandha might have potential anti-arthritic properties that may be widely accepted and reported. Ashwagandha might help relieve pain by soothing the nervous system. In an experimental study6, patients were given a formula containing ashwagandha. This herbal formulation showed the potential to reduce the severity of pain and disability1,4. However, arthritis is a serious condition and must be diagnosed and treated by a doctor.

3. Ashwagandha for Cognition (Learning and Memory)

Ashwagandha is a popular Ayurvedic rasayana and belongs to medhyarasayanas, a subgroup of rasayanas. Medhya means mental/intellectual ability. Ashwagandha might help enhance memory and intelligence. This potential of ashwagandha for cognition was seen in children with compromised memory and old age as anecdotal evidence1. However, such claims lack scientific backup. Therefore, more research is required.

4. Ashwagandha for Stress

The circulatory system and cardiovascular health are adversely affected due to mental stress. Stress also affects the body’s antioxidant defence system7. Ashwagandha might help the body adapt to stress. It may also be effective in improving mental and physical health5. However, more research is required to ascertain such claims.

5. Ashwagandha for Pain

In a study8, treatment with an aqueous extract of ashwagandha showed potential to increase the pain threshold (a point beyond which a trigger produces pain) compared to that of placebo, showing that ashwagandha might be an analgesic agent. However, further research is required to state these as concrete facts.


Other Potential Uses of Ashwagandha

Ashwagandha might help deal with problems related to sleep and may contain sleep-inducing properties. It might also help one fall asleep faster and have an improved sleep quality7.

Though there are studies that show the potential uses of ashwagandha in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of ashwagandha on human health. 

Ashwagandha may be helpful in combating hair loss and promoting hair growth. Hair loss usually occurs due to stress. The lactones present in ashwagandha can reduce the levels of cortisol hormone in the body, which relieves stress10.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

PharmEasy Recommends: EverHerb Ashwagandha


How to Use Ashwagandha

The important formulations of ashwagandha include:

  • Asvagandhadyarishta (syrup form)
  • Asvagandhadi leha (powder form)
  • Balasvagandha lakshadi taila (oil form)

It is also available in the form of tea, pills, gummies, or tincture. The roots, seeds, leaves, and flowers of ashwagandha can be used for medicinal purposes.

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Did you know ashwagandha contains high levels of polyphenols, mainly catechin, which is responsible for its antioxidant actions? All the parts of ashwagandha, including the roots, leaves and fruits, are rich in catechin, which provides potential health benefits12.

Dr. Smita Barode, B.A.M.S, M.S.

Side Effects of Ashwagandha

The safety of the long-term use of ashwagandha has not been fully documented. However, the most common side effects of ashwagandha are:

  • Nausea
  • Diarrhoea
  • Vomiting
  • Stomach upset7

The less common side effects are:

  • Drowsiness
  • Vertigo (dizziness)
  • Cough and congestion
  • Rashes
  • Blurred vision
  • Dry mouth
  • Weight gain
  • Hallucinations7

Ashwagandha might also cause liver damage. It is essential to call your healthcare provider when you experience any side effects, particularly those consistent with liver damage like itchy skin or jaundice7. Therefore, kindly consult an Ayurvedic physician before using ashwagandha. They will tailor the prescription according to your health needs.

Ashwagandha may be helpful in improving the performance of swimmers as it boosts stamina. It is possible that the duration that can be covered by swimmers taking ashwagandha is longer than those not taking it1.

Dr. Ashok Pal, B.A.M.S.

Precautions to Take with Ashwagandha

Ashwagandha must be avoided in some conditions like:

  • Pregnancy
  • Breastfeeding
  • Autoimmune diseases (conditions where the immune system attacks the body’s own tissues)
  • Recent surgery or an upcoming surgical procedure
  • Thyroid disorders7

Kindly do not self-medicate, alter, replace, or discontinue any ongoing treatment. Please consult a doctor.

Ashwagandha is derived from two words: ashwa, meaning ‘horse’ and gandha, meaning ‘smell’. It is named so because the fresh roots of ashwagandha emit the smell of a horse. It is believed to boost vitality and strength in your body, comparable to a horse11.

Dr. Rajeev Singh, BAMS

Interactions With Other Drugs

It is essential to take precautions when using ashwagandha with:

  • Barbiturates (a group of drugs that cause relaxation or sleepiness): Ashwagandha might aggravate the effect of barbiturates. Hence, caution must be taken while taking this combination.
  • Alcohol: It is not advisable to take ashwagandha with alcohol.
  • Sedatives: Ashwagandha should not be taken with health products with sedative properties.

To make sure that ashwagandha does not interfere with other medications, it is essential to consult your physician4.

Frequently Asked Questions (FAQs)

What is ashwagandha?

Ashwagandha is a well-known herb used in Ayurvedic medicine. Its common names include winter cherry and Indian ginseng. It is obtained from a small evergreen shrub known as Withania somnifera. Ashwagandha might be helpful for a wide variety of ailments7.

Where is ashwagandha commonly cultivated?

In India, ashwagandha is cultivated in Uttar Pradesh, Gujarat, Rajasthan, Punjab and Madhya Pradesh4.

Can ashwagandha be used for the common cold?

The decoction of the roots of ashwagandha might be helpful for colds and chills. The root bark might be helpful for asthma4. Kindly do not self-medicate. Consult a doctor before taking ashwagandha for the common cold.

Can ashwagandha be used as an anti-inflammatory agent?

In Ayurvedic medicine, the root of ashwagandha is used as an anti-inflammatory agent by an Ayurvedic physician for dealing with tumours, swellings, scrofula (a type of tuberculosis), and rheumatoid arthritis (a condition affecting joints and bones)4. However, you are advised not to use ashwagandha for the above-mentioned conditions by yourself. Kindly consult an Ayurvedic physician for the same.

What are the indications of ashwagandha in Ayurvedic medicine?

Ashwagandha is indicated in conditions like syncope (temporary loss of consciousness associated with insufficient blood flow to the brain), piles, tumours, cervical lymphadenitis (enlargement of neck lymph nodes), gout (a type of arthritis), diseases of the skin, vitiligo (a disorder that causes the skin to lose color), lockjaw, heart failure, abscesses (a painful collection of pus), stiffness of the knee, cachexia (muscle and weight loss), bone fracture and diabetic carbuncle (cluster of painful boils)4. Kindly consult a doctor. Do not self-medicate.

What does ashwagandha do?


Ashwagandha, an adaptogenic herb, is known to reduce stress, boost immunity, improve cognitive function, and enhance overall vitality. Its active compounds may help regulate cortisol levels, promote relaxation, and support physical endurance, making it a popular choice in traditional medicine and wellness practices.

How much ashwagandha needs to be consumed per day?

The recommended dosage of ashwagandha typically ranges from 300 mg to 600 mg per day for most adults, divided into two or three doses. However, it’s crucial to consult with a healthcare professional to determine the appropriate dosage based on individual health factors and specific needs.

Can ashwagandha increase weight?

While ashwagandha is generally not associated with weight gain, some studies suggest it may support weight management by reducing stress-related overeating and regulating cortisol levels. However, individual responses may vary, and it’s advisable to consult with a healthcare provider before incorporating ashwagandha into a weight management regimen.

Can ashwagandha increase testosterone?

Ashwagandha has been studied for its potential to increase testosterone levels in men with low levels or infertility issues, attributed to its ability to reduce stress and improve overall hormonal balance. While research shows promising results, individual responses may vary, and consulting with a healthcare professional is advisable before using ashwagandha for this purpose.

References

  1. Narendra Singh, Mohit Bhalla, Prashanti de Jager, Marilena Gilca; An overview on ashwagandha: A rasayana (rejuvenator) of Ayurveda. African journal of traditional, complementary and alternative medicines. 2011 June 3 8(5): 208-213 Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/
  2. Kruthika Joshi, Swagata D Tavhare, Kalpesh Pandra, Praveen Kumar; Studies of Ashwagandha (withania Somifera Dunal). International journal of pharmaceutical and biological archives. 2016 7(1): 1-11. Available from: https://www.researchgate.net/publication/303343480_Studies_of_Ashwagandha_Withania_somnifera_Dunal/link/573dbb3908ae9ace84111bb9/download
  3. Swati Dongre, Deepak Langade, And Sauvik Bhattacharyya; Efficacy and safety of ashwagandha (withania somnifera) root extract in improving sexual function in women: A pilot study. BioMed Research International. 2015 Oct. Available from: https://www.hindawi.com/journals/bmri/2015/284154/
  4. Sleep foundation. Ashwagandha for sleep. [Internet] Available from: https://www.sleepfoundation.org/naturalsleepaids/ashwagandha#:~:text=unknown%20side%20effects.,Ashwagandha%20as%20a%20Sleep%20Aid,%25%20better14%2C%20on%20average
  5. The Ayurvedic Pharmacopoeia of India. Part-1 Volume-1. Available from: http://www.ayurveda.hu/api/API-Vol-1.pdf
  6. Ramakanth GS, Uday Kumar C, Kishan PV, Usharani P. A randomized, double blind, controlled study of efficacy and tolerability of Withaina somnifera extracts in knee joint pain. J Ayurveda Integr Med. 2016 Jul-Sep;7(3):151-157. doi: 10.1016/j.jaim.2016.05.003. Epub 2016 Sep 16. PMID: 27647541; PMCID: PMC5052364. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5052364/
  7. Office of Dietary Supplements (ODS), National Institutes of Health. Ashwagandha: Is it helpful for stress, anxiety, or sleep? [Internet]. Bethesda (MD): NIH; [updated 2 May 2025; cited YYYY Mon DD]. Available from: https://ods.od.nih.gov/factsheets/Ashwagandha-HealthProfessional/
  8. Bonilla DA, Moreno Y, Gho C, Petro JL, Odriozola-Martínez A, Kreider RB. Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis. J Funct Morphol Kinesiol. 2021 Feb 11;6(1):20. doi: 10.3390/jfmk6010020. PMID: 33670194; PMCID: PMC8006238. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8006238/
  9. Salve J, Pate S, Debnath K, Langade D. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus. 2019 Dec 25;11(12):e6466. doi: 10.7759/cureus.6466. PMID: 32021735; PMCID: PMC6979308. Available from: https://pubmed.ncbi.nlm.nih.gov/32021735/
  10. Ring C, Heitmiller K, Correia E, Gabriel Z, Saedi N. Nutraceuticals for Androgenetic Alopecia. J Clin Aesthet Dermatol. 2022 Mar;15(3):26-29. PMID: 35342503; PMCID: PMC8944288. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8944288/
  11. Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022. PMID: 23439798; PMCID: PMC3573577. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3573577/
  12. Alam N, Hossain M, Khalil MI, Moniruzzaman M, Sulaiman SA, Gan SH. High catechin concentrations detected in Withania somnifera (ashwagandha) by high performance liquid chromatography analysis. BMC Complement Alternat Med. 2011 Aug 19;11:65. doi:10.1186/1472‑6882‑11‑65. Available from: https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/1472-6882-11-65

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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