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पीएसए टेस्ट (PSA Test in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

परिचय

प्रोस्टेट-विशिष्ट एंटीजन (पीएसए) परीक्षण एक खून परीक्षण है जो आपके खून में पीएसए के स्तर को मापता है। पीएसए पुरुषों में प्रोस्टेट ग्रंथि द्वारा उत्पादित एक पदार्थ है। प्रोस्टेट कैंसर की जांच के लिए पीएसए टेस्ट का इस्तेमाल किया जाता है। 

पीएसए परीक्षण के लिए नमूना प्रकार

पीएसए टेस्ट ब्लड सैंपल लेकर किया जाता है। यह टेस्ट अलग से किया जाता है या अन्य रूटीन ब्लड टेस्ट के साथ किया जा सकता है।

आपको पीएसए परीक्षण कितनी बार करना चाहिए?

पीएसए परीक्षण आपके लक्षणों और आपके डॉक्टर की सलाह के आधार पर दोहराया जाता है। यदि आपके पीएसए का स्तर अधिक है, तो प्रोस्टेट कैंसर की निगरानी के लिए आपको हर 6-8 सप्ताह में पीएसए परीक्षण दोहराने की आवश्यकता हो सकती है। यदि आपके पीएसए स्तर सामान्य सीमा के भीतर हैं, तो आप हर 2-4 साल में परीक्षण दोहरा सकते हैं।

पीएसए परीक्षण एक बहुत ही सटीक परीक्षण नहीं है क्योंकि यह आपको निम्नलिखित कारणों से गलत-सकारात्मक परिणाम दे सकता हैः

पीएसए परीक्षण के लाभ

पीएसए टेस्ट के नुकसान

पीएसए परीक्षण के अन्य नाम

टेस्ट समावेशन: पीएसए परीक्षण में कौन से पैरामीटर शामिल हैं?

पीएसए टेस्ट रिपोर्ट आपके शरीर में मौजूद प्रोस्टेट-विशिष्ट एंटीजन (PSA) का पता लगाती है।

पीएसए परीक्षण क्या मापता है और पीएसए परीक्षण किसके लिए निर्धारित है?

पीएसए परीक्षण आपके शरीर में प्रोस्टेट-विशिष्ट एंटीजन के स्तर को मापता है। पीएसए एक प्रोटीन है जो पुरुषों में प्रोस्टेट ग्रंथि में कोशिकाओं द्वारा उत्पादित होता है। आमतौर पर पुरुषों में पीएसए का स्तर कम होता है। पीएसए के उच्च स्तर प्रोस्टेट कैंसर, सौम्य प्रोस्टेटिक वृद्धि या प्रोस्टेट ग्रंथि (प्रोस्टेटाइटिस) के संक्रमण को इंगित करते हैं। 

पीएसए परीक्षण उन पुरुषों के लिए निर्धारित किया जाता है जिनमें  निम्नलिखित कारणों से  प्रोस्टेट कैंसर होने की संभावना ज्यादा होती है :

पीएसए परीक्षण उन लोगों को करवाया जाता है  जो निम्नलिखित लक्षणों का अनुभव करते हैंः

प्रोस्टेट कैंसर के उपचार की प्रभावशीलता की निगरानी के लिए पीएसए परीक्षण का भी उपयोग किया जाता है। एक बार जब आपको प्रोस्टेट कैंसर का पता चल जाता है, तो आपको बीमारी के पूर्वानुमान के लिए पीएसए परीक्षण करने की आवश्यकता होगी।

यह भी पढ़ें: खून यूरिया नाइट्रोजन परीक्षण (Blood Urea Nitrogen Test): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब करना चाहिए

अक्सर पूछे जाने वाले सवाल (FAQs)

उम्र के आधार पर एक सामान्य पीएसए क्या है?

सामान्य पीएसए स्तर  2.5 एनजी / एमएल फिर कम होना चाहिए।  उम्र के हिसाब से 60 या 70 वर्ष से अधिक पुरुषों में 4.0 एनजी / एमएल से ज्यादा पीएसए  असामान्य  माना जाता है।

क्या उच्च पीएसए का मतलब हमेशा कैंसर होता है?

नहीं, एक ऊंचा पीएसए स्तर का मतलब हमेशा कैंसर ही नहीं होता।। प्रोस्टेटाइटिस,  प्रोस्टेटिक हाइपरप्लासिया या बढ़ती उम्र के कारण आपका पीएसए उच्च हो सकता है। यदि निदान की पुष्टि करने के लिए आपका पीएसए स्तर उच्च है तो आपका डॉक्टर प्रोस्टेट बायोप्सी की सलाह देंगे। ।

क्या पीएसए परीक्षण कैंसर का पता लगाता है?

हां, पीएसए टेस्ट प्रोस्टेट कैंसर का पता लगाने में मदद करता है। हालांकि, यह हमेशा सटीक नहीं होता है और प्रोस्टेट कैंसर की पुष्टि करने के लिए अतिरिक्त रूप से अन्य परीक्षणों की आवश्यकता होगी।

क्या 6.5 का पीएसए खराब है?

आपकी उम्र और लक्षणों के आधार पर आपके पीएसए स्तर को उच्च या खराब माना जा सकता है। 6.5  पीएसए  आने पर आपको अपने चिकित्सक की सलाह लेनी चाहिए।

पीएसए स्तर पर बायोप्सी किस स्तर पर की जानी चाहिए?

यदि आपके पीएसए स्तर 10 एनजी / एमएल से अधिक हैं, तो आपको प्रोस्टेट कैंसर की पुष्टि करने के लिए प्रोस्टेट बायोप्सी की आवश्यकता हो सकती है। पीएसए 10 से कम भी हो पर लक्षणों के आधार पर अगर आपके डॉक्टर को जरूरी लगता है तो वह आपको बायोप्सी की सलाह दे सकते हैं।

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Vacha (Acorus calamus): Uses, Benefits and Side Effects By Dr. Rajeev Singh

Introduction

In the Ayurvedic medicine system, Vacha may be considered a well known medicinal herb used for over 100 years. Vacha, scientifically known as the Acorus calamus, belongs to the family Acoraceae. The Vacha plant is a grass like semi-aquatic herb that grows in moist, marshy lands like ponds, rivers and swamps. Vacha plant is an aromatic herb with creeping rhizomes which has a pleasant and sweet odour due to its essential oils. According to the Red Data Book, the Vacha plant has been considered one of the threatened species. It is native to India and grows in the marshy lands of Kashmir, Manipur and Nagaland. However, it is also found in other countries such as Europe, Russia, Asia, China, Sri Lanka, Japan, Burma, Indonesia, the USA and Canada. Other names of the Vacha plant are calamus, sweet calomel, sweet flag, sweet sedge, myrtle flag, Haimavati, Sadgrantha, Bach, Vekhand, etc1,3.​​ Let us read more about the Vacha plant benefits, nutritional facts, potential uses and more. 

Nutritional Value of Vacha

One hundred grams of Vacha may have 121.65 Kcal of energy4.​​ The nutritional value of the Vacha plant is as under: 

β-asarone is the major phytochemical constituent present in Vacha. Furthermore, other phytonutrients like tannins, β carotene, phytic acids, choline, flavones, ethanol methanol, camphor, eugenol and phenols may also be present in Vacha1,2,4.​

Properties of Vacha

Vacha medicinal plant may include the following properties1,5:

Potential Uses of Vacha

The following may be the potential uses of Vacha: 

1. Potential uses of Vacha for Diarrhoea

stomach pain

Vacha may have anti-diarrhoeal activity. An animal study1,2 by Kapadia et. al in 2012 reported that Vacha plant extract might contain phytochemicals like glycosides and saponins. These phytochemicals in the extract may help relieve symptoms of diarrhoea and dysentery. The experimental analysis showed that a single dose of Vacha extract significantly decreased the severity of diarrhoea and reduced the rate of excretion in animal models. However, this information is insufficient as this study is conducted on animals. More human research is needed to suggest the uses of the Vacha plant for diarrhoea. If you have diarrhoea, consult with doctors and do not self-medicate.

2. Potential uses of Vacha for Constipation

digestion

A diet low in fibre might cause complications like constipation. A study4 by Oyenuga and Fetuga in 1975 suggests that the crude fibre content of the Vacha plant rhizome is as high as about 6.5%. Adding fibre to a diet might help absorb essential minerals in the stomach, increase the digestion process and decrease cholesterol absorption. However, excess consumption should be avoided. Hence Vacha may possess beneficial effects on constipation. Furthermore, clinical studies are needed to continue using Vacha for constipation. To solve your constipation problems, consult a specialist. Avoid self-medication. 

3. Potential Uses of Vacha for Ulcers

Gastric Ulcers

The Vacha rhizome extract may have anti-ulcer activity. An animal testing experiment by Rafatullah et al. 1994 suggests that it may contain certain compounds that might stop the stomach’s acidic secretion and help defend the mucosal lining from ulcer causing agents2 . However, further research in humans is needed to use the Vacha plant for managing ulcers. If you have ulcers, kindly consult a qualified doctor and get proper treatment. 

4. Potential uses of Vacha for Mental Disorders

may trigger mental illness

The Vacha plant in Ayurveda may have been listed as a traditional plant used as a brainpower-enhancing agent that can act against mental disorders including depression. A study1,2 by Manikandan et al., 2005 suggested that Vacha extract may decrease the brain lipid peroxide (free radicles damage the brain cells). This might have a beneficial effect on memory disorder and learning performance. When combined with Polygala root, Vacha might help maintain the mental well-being and intellectual power of the elderly. It may also help with memory loss, confusion, consciousness loss and forgetfulness. Vacha plant may act as a rejuvenator, enhancing brain functions and building memory power. More human research is required to study the true scope of Vacha on mental health. Consult a qualified doctor for any mental health difficulties. 

5. Other Potential Uses of Vacha

vacha
Image Source: freepik.com

Though studies show the potential uses of Vacha in various conditions, these are insufficient and there is a necessity for further studies to develop the scope of the benefits of Vacha on human health.  

Based on what I have noticed, Vacha has been proven beneficial for various conditions in traditional medicine. It is known to possibly help reduce swelling and address skin conditions effectively.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Vacha?

You may use the Vacha plant as follows: 

You should consult a qualified doctor before having Vacha in large quantities. Do not discontinue or replace an ongoing modern medical treatment with an ayurvedic/herbal preparation of Vacha without consulting an ayurvedic physician. They will guide you with its form and dosage per your health condition. 

Judging from what I have seen, Vacha has a unique ability to control elevated body temperature caused by Glycopyrrolate (a medication). This might be helpful for patients who already have high body temperature, as it promotes sweating and helps regulate body heat6.

Dr. Rajeev Singh, BAMS

Side Effects of Vacha

Safety analyses of Vacha on animals have shown that Vacha extract may have toxic effects. Below may be some Vacha plant side effects: 

If you experience such side effects, immediately consult a doctor and get the proper treatment.  

Based on my experience, I can say that Vacha works wonders when it comes to easing uncomfortable cold in children. It’s like a wonder medicine for cough and sore throat! By simply sucking on a small piece of Vacha, children with difficult cold and cough might find relief from these uncomfortable conditions7.

Dr. Smita Barode, B.A.M.S, M.S.

Precautions to Take with Vacha

Having Vacha in small quantities might be safe. However, eating in more significant amounts may be harmful. Therefore, precautions are necessary: 

Also Read: Barley: Uses, Benefits & Side Effects

Interactions with Other Drugs

Vacha plants may interfere with certain drugs/medicines, leading to herb drug interaction. 

Therefore, you should avoid having Vacha preparations with any medicine and if any complications arise, take doctor’s consultations.  

Also Read: Nishigandha (Tuberose): Uses, Benefits and Side effects by Dr. Smita Barode

Frequently Asked Questions (FAQs)

What are the side effects/safety issues of the Vacha plant?

The Vacha plant side effects may include stomach irritation, disturbed digestion, persistent constipation, gastroenteritis, diarrhoea and passage of blood into the faeces2,4. If you experience such side effects after having Vacha preparations, immediately consult a doctor and get appropriate medication.  

What are the other names of Vacha?

Vacha plant in Hindi is called Bach in English is called Calamus, Sweet Calomel, Sweet Flag, Sweet Sedge, Myrtle Flag in Marathi is called Vekhand and in Sanskrit is called Haimavati and Sadgrantha1,3.​

What are the properties of the Vacha plant? 

Vacha plant may have activities such as antifungal, antioxidant, antibacterial, anti-ulcer antispasmodic, analgesic, anti-inflammatory, anticonvulsant, blood sugar-lowering and lipid-lowering properties. It may also act as a rejuvenator, expectorant, calming and sleep-inducing agent. It may help relieve flatulence and help stop the abnormal growth of cancer cells1,5.​ 

Is the Vacha plant carcinogenic? 

Animal studies by Taylor et al., 1967 and Goggelmann et al., 1983 suggest that Vacha plant may contain a photochemical called β-asarone, which might be carcinogenic. It might have the potential to cause tumours in animals3. However, more information is needed to suggest the carcinogenic effects of Vacha on humans. Therefore, before having it consult a doctor and do not self-medicate. 

Does the Vacha plant interact with other drugs?

 Vacha plant extract may interact with particular anti-depressant medicines (MAO inhibitors)3. Therefore, you should avoid having Vacha extract and anti-depressant drugs simultaneously to avoid herb-drug interaction. 

References

  1. ​​KUMAR A. Medicinal Properties of Acorus calamus. J of Drug Deli and Therapy. 2013;3(3):143–4. Available from: http://jddtonline.info/index.php/jddt/article/view/528 
  2. Sharma V, Singh I, Chaudhary P. Acorus calamus (The Healing Plant): a review on its medicinal potential, micropropagation and conservation. Natu Prod Res. 2014;28(18):1454–66. Available from:- https://pubmed.ncbi.nlm.nih.gov/24824923/ 
  3. Yende S, Tuse T, Yende S, Harle U, Rajgure D, Tuse T, et al. Pharmacological profile of Acorus calamus: An Overview. Phcog Rev. 2008;2(4):22–6. Available from: https://www.researchgate.net/profile/Subhash-Yende/publication/207178406
  4. Chandran P, Nair A. Nutritional and Anti Nutritional Status of Acorus calamus L. Rhizome. Annals Food Sci and Techno. 2014;15(1):51–9. Available from: https://www.researchgate.net/publication/265599969
  5. Balakumbahan R, Rajamani K, Kumanan K. Acorus calamus: An overview. J of Med Plants Res. 2010;4(25):2740–5. Available from: https://academicjournals.org/article/article1380712717_Balakumbahan%20et%20al.pdf 
  6. AYU (An International Quarterly Journal of Research in Ayurveda) [Internet]. Wolters Kluwer – Medknow; [cited 2026 Jan 13]. Available from: https://journals.lww.com/AAYU/pages/default.aspx
  7. Kaushik P. Role of Vacha in neurological disorders in paediatrics- a review. World Journal of Pharmaceutical Research. 2022;11(4):2301–2308. Available from: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/be1e0cc61073ea97dc0b523c90161fc2.pdf

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any change

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Pancharishta: Uses, Benefits and Side Effects By Dr. Rajeev Singh

Introduction

Ayurveda has enlisted the importance of various Arishtas (herbal decoctions) and Asavas (herbal infusion) which are self-fermented polyherbal preparations. These may be well known for the management of digestive and metabolic disorders. One such preparation is Pancharishta. Pancharishta is a traditional Ayurvedic polyherbal syrup (different herbs) popularly used for centuries in India. It is a combination of Asavas and Arishtas. This polyherbal Pancharishta is made by combining and fermenting thirty-five different Ayurvedic herbal plants. Pancharishta may be considered a unique medicinal wine. It is a self-formed alcoholic preparation that may contain approximately 12% of alcohol. Pancharishta syrup formulations may have been used widely from the ancient period without knowing any side effects1,3.​​ Let us discuss the health benefits of Pancharishta, its nutritional ingredients, potential uses and more.

Nutritional Value of Pancharishta

Below listed are the ingredients of Pancharishta (Value in %): 

Pancharishta may also contain other ingredients such as ajwain, clove, sugar cane, cumin, coriander, aloe vera and Kunwa (Yeast). It may also contain bioactive phytochemicals like phenol, tannin, saponins, glycosides, carbohydrates, flavonoids, gingerol, piperine and alcohol1,3

Properties of Pancharishta

Pancharishta syrup may include the following biological properties: 

As Pancharishta is a polyherbal solution prepared by fermentation, it might have detoxification effects on the body due to the presence of various flavonoid and phenolic compounds.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Pancharishta

The following may be the potential uses of Pancharishta syrup: 

1. Potential Uses of Pancharishta for Hyperacidity

Hyperacidity

Hyperacidity is caused due to rise in digestive juices creating an acidic environment in the stomach. It may cause heartburn, indigestion, gas etc. An animal study3 by Adhikari et al. 2018 found that Pancharishta contains herbs that may reduce the secretion of stomach acid and increase the pH in the stomach. Thus, it may help in lowering stomach acids and relieving hyperacidity. However, human research is needed to conclude the use of Pancharishta for hyperacidity. If you experience frequent acidity, consult a specialist doctor. Avoid self medication.  

2. Potential Uses of Pancharishta for Digestion

improve digestion

Pancharishta syrup is a fermented decoction. It comprises several ‘good bacteria’ which may enhance the digestion process. It may be used as a digestive tonic which may help release digestive enzymes allowing proper digestion of food. It also contains ingredients like Tvak, Lavanga, Tvakpatra and Dhanyaka these are carminative herbs. These may contribute to carminative activity releasing flatulence, bloating, gas and indigestion. Adhikari et al. 2018 suggest Pancharishta may help with digestion in animals. Further human studies are expected to support the benefits of Pancharishta for digestion1,3. If you have digestion problems take the doctor’s advice. Do not self-medicate. 

Pancharishta is a polyherbal medicine made by ancient Ayurvedic methods known as Arishta and Asava. It is commonly used as a digestive and cardioprotective tonic.

Dr. Rajeev Singh, BAMS

3. Potential Uses of Pancharishta for Stomach Cramps/Pain

stomach pain

People might experience stomach pain and stomach cramping due to various digestion issues. An animal study3 by Adhikari et al. 2018 reported that Pancharishta may have anti-spasmodic activity. It may help contractions of stomach muscles. It may assist in relaxation and stop cramps in the stomach and intestine. This may help reduce stomach upsets and pain. Further studies are needed to completely understand the effects of Pancharishta on stomach cramps. Consult a qualified physician and take Pancharishta only if recommended.  

4. Potential Uses of Pancharishta for Gastric Ulcers

Gastric Ulcers

Gastric ulcers happen due to an imbalance in stomach acids and bacterial infection by Helicobacter pylori. A study3 by Adhikari et al. 2018 observed that gastric ulcers may be reduced with the polyherbal formulation of Pancharishta. It may have the action of safeguarding the stomach mucosal lining and maintaining its structure. Hence, Pancharishta may help preserve the cell lining of the stomach and defend against gastric ulcers. However, this is an animal study, more human studies are required to find the true Pancharishta uses for ulcers. Take medical help if you have gastric ulcers. Self-medication is not recommended. 

5. Potential Uses of Pancharishta for Stomach Emptying

Gastroparesis is a condition that may affect the regular movement of the muscles in the stomach. This might hamper the stomach emptying. An animal study3 by Adhikari et al., 2018 discovered that Pancharishta ingredients may help empty the stomach. This property has been confirmed in animals however, human studies are awaited to support the true use of Pancharishta for stomach emptying. Consult a doctor if you are experiencing stomach issues. 

6. Other Potential Uses of Pancharishta

Peptic Ulcer

Though studies show the potential uses of Pancharishta in various conditions, these are insufficient and there is a necessity for further studies to develop the scope of the benefits of Pancharishta on human health.  

How to Use Pancharishta?

You should consult a qualified doctor before having Pancharishta in large quantities. Do not discontinue or replace an ongoing modern medical treatment with an ayurvedic/herbal preparation of Pancharishta without consulting an ayurvedic physician. They will guide you with its form and dosage per your health condition. 

Side Effects of Pancharishta

However, more human research is needed to study the side effects of Pancharishta in humans. You must always consult your doctors and get the proper treatment if you come across side effects.

Also Read: Kumaryasava: Uses, Benefits, Side Effects & More!

Precautions to Take with Pancharishta

Pancharishta in the prescribed dose might be safe. However, having it in larger amounts may produce harmful effects. Therefore, a few precautions are essential:  

Also Read: Gulkand(Rose Petal Jam): Uses, Benefits, Side Effects By Dr. Smita Barode

Interactions with Other Drugs

Furthermore, clinical studies are required to suggest the herb-drug interaction between Pancharishta and other medicines. We direct that you consult with a doctor before taking Pancharishta preparation and only take it in the given dosage.  

Also Read: Guduchi (Giloy): Uses, Benefits, Side Effects and More!

Frequently Asked Questions (FAQs)

What is Pancharishta syrup? 

Pancharishta is an Ayurvedic decoction formulation of thirty-five different Ayurvedic herbs. It is a combination of Asava and Arishta. Pancharishta syrup is an alcoholic preparation that may contain 12% of self-generated alcohol. It has been widely used for all stomach-related disorders1,3.

What are the properties of Pancharishta? 

Pancharishta properties may include carminative, laxative, antioxidant, anti-ulcer, digestive, anti-inflammatory and anti-spasmodic. It may help enhance immunity, reduce stomach acidity and help maintain liver health1,3. If you have any such issues consult with your doctors and avoid self-medication. 

How many ingredients are there in Pancharishta? 

Pancharishta may contain thirty-five different plant ingredients. The major ingredient of Pancharishta may be a flower called Dhataki (Woodfordia fruticosa)1,2

What are the effects of Pancharishta overdose?

Overdosing on Pancharishta should be avoided. It contains a moderate amount of alcohol1. Therefore, excess consumption of Pancharishta might cause symptoms such as vomiting, mental confusion, dizziness, etc. It is best to avoid overdosing and if any complication appears immediately, seek medical help.  

Is Pancharishta safe during pregnancy? 

No studies have reported the safe use of Pancharishta during pregnancy. Pregnant women should always consult their doctors before using any Ayurvedic preparations such as Pancharishta. They will advise you on the best form and dosage. Do not self-medicate. 

References

  1. ​​Pandey D, Verma K, Dwivedi L. Phytochemical And in-Vitro Characterization of Pancharishta: A Classical Herbal Remedy. NeuroQuantology. 2022;20(17):740–3. Available from: https://www.researchgate.net/profile/Diksha-Pandey-15/publication/366005966_Nq88092_Diksha_Pandey_Kalpana_Verma_LK_Dwivedi_Phytochemical_And_in_Vitro_Characterization_of_Pancharishta_A_Classical_Herbal_Remedy_eISSN/links/638da2c62c563722f23c6749/Nq88092-Diksha-Pandey-Kalpana-Verma-LK-Dwivedi-Phytochemical-And-in-Vitro-Characterization-of-Pancharishta-A-Classical-Herbal-Remedy-eISSN.pdf 
  1. ​Khan W, Chester K, Anjum V, Ahmad W, Ahmad S, Narwaria A, et al. Chromatographic profiling of Pancharishta at different stages of its development using HPTLC, HPLC, GC–MS and UPLC–MS. Phytochem Lett. 2017; 20:391–400. Available from: https://www.sciencedirect.com/science/article/abs/pii/S1874390017302823?via%3Dihub 
  1. ​Adhikari A, Dey A, Kanjilal S, Biswas R, Gandhi D, Mondal K, et al. Gastroprotective and digestive potential of an Ayurvedic asava–arishta preparation. Ori Pharm and Exp Med. 2018;18(4):391–401. Available from: https://link.springer.com/article/10.1007/s13596-018-0325-y 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Chandanasava: Uses, Benefits and Side Effects by Dr. Smita Barode 

Introduction

Ayurvedic formulations may have emerged as a traditional alternative for a variety of health problems. Chandanasava is one such Ayurvedic formulation that may be considered a traditional medicine. Chandanasava is an Ayurvedic polyherbal formulation prepared using one or more medicinal herbs. The name Chandanasava is derived from one of the main ingredients, Chandan, known as sandalwood in English. Asava in Chandanasava refers to a fermented infusion that is produced by microbes. Chandanasava has a moderate alcohol content and is made with herbal juices from 24 different herbs. Chandanasava can be fermented with sugar, honey, or jaggery. For Chandanasava preparation, an equal amount of herb powder is mixed with water, as well as jaggery and sugar, and the mixture is boiled and chilled. This is then poured into large vessels and left to ferment for several days. It may belong to the alcohol-based category of drugs. Chandanasava could have been used as a valuable medicine to enhance health1,3​.​ Let us discuss the health benefits of Chandanasava, its nutritional value, potential uses, and more.  

Nutritional Value of Chandanasava

Below listed are the Chandanasava ingredients: 

Furthermore, phytochemical compounds like glucosides, alkaloids, phytosterols, stilbenes, terpenoids, phenols, flavonoids, glycosides, tannins, saponins and various alcohols and non‑volatile compounds may also be present in it1,2

Properties of Chandanasava

The benefits of Chandanasava may be due to the following properties:  

Potential Uses of Chandanasava

Chandanasava may be ideal for enhancing human health2. The following may be the potential uses of Chandanasava: 

1. Potential Uses of Chandanasava for Body Heat

hot flashes

Women in their forties and fifties may experience physiological changes that cause mild to severe symptoms such as hot flashes, body heat, night sweats, and a burning sensation. Certain phytochemicals in Chandanasava may have cooling properties. Regularly consuming Chandanasava (15-30 ml) with water may produce cooling effects within the body. These properties of Chandanasava may aid in the relief of symptoms such as hot flashes, body heat, night sweats, and a burning sensation5. More human research is required to suggest Chandanasava’s true use for body heat. Consult your doctor if you experience excessive body heat. Do not attempt to self-medicate. 

2. Potential Uses of Chandanasava for the Kidney

kidney health

A study4 by Vinothkanna et. al. in 2022 showed Chandanasava may be used against chronic kidney diseases (a long-term kidney failure). It may contain compounds such as piperine and melatonin which may have the potential to stop the bacterial layer (biofilm) formation of infectious diseases involved in kidney diseases. More clinical research is required to form the true scope of Chandanasava against chronic kidney diseases. If you have kidney dysfunction, seek medical attention. 

Chandanasava is a polyherbal Ayurvedic formulation. This formulation consists of many nutrients. Research suggests that there are some ten bioactive compounds. These bioactive compounds might be beneficial for managing various systemic diseases like chronic kidney diseases, cardiovascular diseases, etc4.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

3. Potential Uses of Chandanasava for Urinary Tract Infection (UTI)

urinary tract infections

The most common clinical condition among people may be urinary tract infection. Burning sensations and dysuria are possible side effects (difficulty in urination). Chandanasava may be used as a urinary antiseptic. It may have a diuretic effect that may increase urine production and help clear out the urine passage, providing relief from urinary tract infections. Goel and Singh (1991) discovered that the ingredients in Chandanasava may have antimicrobial and antiseptic activity in a clinical trial. This activity may aid in the relief of symptoms such as burning and dysuria6. More human trials are required to establish the efficacy of Chandanasava for UTI. However, if you have a UTI, please take proper medication and do not self-medicate. 

4. Potential Uses of Chandanasava for Peptic Ulcer

Peptic Ulcer

Dixit et al. (2012)3 discovered that Chandanasava has antiulcer activity in animals. A stomach juice imbalance can cause a peptic ulcer. Chandanasava may be used as a therapeutic agent to improve stomach conditions. It contains flavonoids, tannins, and terpenoids, all of which have antiulcer properties. As a result, Chandanasava may be beneficial in the healing of peptic ulcers in patients. However, more research is needed to determine Chandanasava’s antiulcer activity. Consult a doctor if you have ulcers. 

5. Other Potential Uses of Chandanasava

arthritis

Though studies show the potential uses of Chandanasava in various conditions, these are insufficient and there is a necessity for further studies to develop the scope of the benefits of Chandanasava on human health.  

How to Use Chandanasava?

You should consult a qualified doctor before having Chandanasava in large quantities. Do not discontinue or replace an ongoing modern medical treatment with an Ayurvedic/herbal preparation of Chandanasava without consulting an Ayurvedic physician. They will guide you with its form and dosage per your health condition. 

Side Effects of Chandanasava

However, more human research is needed to study the adverse effects of Chandanasava on humans. You must consult your doctors to get the proper treatment if you encounter side effects. 

Chandanasava is formulated using self-fermentation methods known as Arishtas and Asavas. Studies show that Chandanasava might have antibacterial and anthelmintic activities and might be useful against bacterial and parasitic infections7.

Dr. Rajeev Singh, BAMS

Also Read: Nagkesar (Mesua Ferrea): Benefits, Uses, Side Effects & More!

Precautions to Take with Chandanasava

Chandanasava in small and prescribed dosages might be safe. However, having it in larger amounts may harm the body. Therefore, a few precautions are essential:  

Also Read: Trikatu Churna: Uses, Benefits and Side Effects by Dr. Rajeev Singh

Interactions with Other Drugs

Chandanasava is a polyherbal Ayurvedic preparation. Its ingredients may or may not interact with other drugs. Further clinical studies are needed to suggest the herb-drug interaction between Chandanasava and other medicines. We advise that you consult with a doctor before taking Chandanasava and only take it in the prescribed dosage.  

Also Read: Vasaka (Malabar Nut): Uses, Benefits and Side Effects by Dr. Rajeev Singh 

Frequently Asked Questions (FAQs)

What is Chandanasava? 

Chandanasava is a polyherbal Ayurvedic formulation. Chandanasava is a fermented formulation made from 24 herbal ingredients. Chandanasava preparation is done using an equal amount of herbs powder in water, jaggery and sugar and boiled and cooled. Then this is poured into big vessels and allowed to ferment for days1

What are the ingredients of Chandanasava? 

The Chandanasava ingredients may include Chandan, Raktachandana, Hribera, Priyangu, Musta, Kashmari, Lodhra, Patola, Madhuka, Indivara, Parpata, Manjistha, Ashwattha, Patha, Vata, Priyangu, Bhunimba, Kanchanara, Shati, Rasna, Mocharasa Amra, Dhataki, Guda, Mridvika, water and sugar1.

What are the properties of Chandanasava? 

Chandanasava may have properties such as diuretic, antioxidant, antimicrobial, appetizer, antiseptic, anti-inflammatory, analgesic and anti-ulcer activity1,6. ​​More studies are needed to confirm the true properties of Chandanasava in humans. 

How to take Chandanasava?

Chandanasava may be taken with water5. However, consult with doctors, they will guide you with its better form and dosage according to your health condition. 

What are the advantages of Chandanasava for Urinary Tract Infection? 

In a clinical trial6 by Goel and Singh, 1991 found that the ingredients of Chandanasava may have antiseptic activity and antimicrobial activity. It may provide relief against urinary tract infections. This activity may help overcome symptoms like burning sensation and dysuria (burning urination).​ More human studies are necessary to state the uses of Chandanasava for UTI. However, if you suspect UTI, take proper medicine and do not self-medicate. 

References

1. ​​Vinothkanna A, Sekar S. Influence of intrinsic microbes on phytochemical changes and antioxidant activity of the Ayurvedic fermented medicines: Balarishta and Chandanasava. Pharmaco Study. 2018; 39:169–81. Available from: https://pubmed.ncbi.nlm.nih.gov/31000995/

​2. Vinothkanna A, Karthikeyan B, Vijayan R, Sekar S. Assessment of anti-arthritic potential of traditionally fermented ayurvedic polyherbal product chandanasava by molecular modelling, docking and dynamics approaches. Intern J of Comput Biol and Drug Design. 2018;11(4):346–68. Available from: https://www.researchgate.net/publication/328949445_Assessment_of_anti-arthritic_potential_of_traditionally_fermented_ayurvedic_polyherbal_product_chandanasava_by_molecular_modelling_docking_and_dynamics_approaches

​3. Dixit P, Sharma P, Jain DK, Jharia V. Systematic Evaluation of Antiulcer Activity of Herbal Formulation ‘Chandanasava’ in Rats. Asian Paci J of Trop Dis. 2012;2(SUPPL.1):192–6. Available from: https://www.researchgate.net/publication/257746795_Systematic_Evaluation_of_Antiulcer_Activity_of_Herbal_Formulation_’Chandanasava’_in_Rats

​4. Vinothkanna A, Prathiviraj R, Sivakumar R, Ma Y, Sekar S. GC–MS and Network Pharmacology Analysis of the Ayurvedic Fermented Medicine, Chandanasava, Against Chronic Kidney and Cardiovascular Diseases. Appl Biochem and Biotech. 2022;1–26. Available from: https://link.springer.com/article/10.1007/s12010-022-04242-7

5. Choudhary P, Smitha MV. The Prevalence of Menopausal Symptoms and its Association with Marital Relationship in Perimenopausal Women of Eastern India. J Midlife Health. 2025 Jul-Sep;16(3):285-294. doi: 10.4103/jmh.jmh_82_25. Epub 2025 Sep 5. PMID: 40951856; PMCID: PMC12431706. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC12431706/

​6. Goel K, Singh R. Clinical Trial of Candanasava, In the Treatment of Urinary Tract Infection. Vol. Anci Sci of Life.1991;X(4):248–52. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3331297/

7. Kumar SV, Sandeep M, Kamal D, et al. Antibacterial and anthelmintic activity of selected fermented Ayurvedic herbal formulations. Drug Invention Today. 2010 Jul;2(7):347-348. Available from: https://web.p.ebscohost.com/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability, or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation of the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Trayodashang Guggulu: Uses, Benefits and Side Effects By Dr. Smita Barode 

Introduction

Trayodashang guggulu is one of the primary Ayurvedic polyherbal formulations. It consists of Babula (the stem bark of Acacia nilotica), Hapusa (the fruits of Juniperus communis), Shatavari (the roots of Aspargus recemosus), Ashwagandha (the roots of Withania somnifera), Sunthi (the rhizome of Zingiber officinale), Satavha (the fruits of Anethum sowa), Vradadaru (the roots of Argyeria nervosa), Sati (the rhizome of Hidichium spicatum), Shuddha guggulu (exudates of Commiphera mukul), Rasana (the roots and leaves of Pluchea lanceolata), Guduchi (the stem of Tinospora cordifolia), Gokshuara (the fruits Tribulus terrestris), Yavani (Trachyspermum ammi fruits) and Goghrat (ghee). The ayurveda formulation trayodashang guggulu is mentioned in the Ayurveda classic Bhaishaja Ratnavali and the Ayurveda Formulary of India. Trayodashang guggulu may be used for various ailments. Let us look at some of the health benefits of trayodashang guggulu1

Nutritional Value of Trayodashang Guggulu

The composition of trayodashang guggulu is as follows: 

Properties of Trayodashang Guggulu

Several studies have shown that Trayodashang guggulu may have the following properties: 

Potential Uses of Trayodashang Guggulu for Overall Health

Some of the potential uses of trayodashang guggulu are: 

1. Potential Uses of Trayodashang Guggulu for Spondylosis

spondylosis

The worst diet habits with the western lifestyle and continuous work in front of laptops are the major reasons for spondylosis. Trayodashang guggulu may be used against spondylosis. A study2 by Sawant et al. in 2017 showed that Trayodashang guggulu might be beneficial for cervical spondylosis. Constituents like Shatavari, Ashwagandha and Guduchi are rejuvenators and may give stability to the muscles (dhatus). Whereas babbul acts on bones (asthidhatwagni) and may provide firmness. However, further studies are required to check if trayodashang guggulu may help in the case of cervical spondylosis. Therefore, you must consult your doctor if you experience any symptoms of cervical spondylosis. Do not self-medicate. 

2. Potential Use of Trayodashang Guggulu as an Antioxidant

trayodashang guggulu as an antioxidant

The phenols, alkaloids, flavonoids and other phenolic compounds present in trayodashang guggulu may show antioxidant activity. This was demonstrated by a study1 by Dadoriya et al. in 2018. It may deactivate the free radicals (harmful molecules present in the body) and protect them from various damages.  Further studies are required to check the antioxidant activity of trayodashang guggulu. 

From my experience, Trayodashang Guggulu may aid in gout. Studies1 suggest that Trayodashang Guggulu shows antioxidant and anti-inflammatory effects that make it a potential remedy in cases of inflammatory disease such as gout.

Dr. Siddharth Gupta, BAMS, MD (Ayu)

3. Potential Use of Trayodashang Guggulu for Inflammation

reduces inflammation

Trayodashang guggulu may be beneficial for several inflammatory conditions like the stiffness of the knee, bone marrow disorder, lockjaw, inflammation of ligaments, neurological and musculoskeletal diseases, pain in the arm and cardiac failure and bone fracture due to the presence of bioactive compounds like flavonoids and phenols. A study1 by Dadoriya et al. in 2018 showed that trayodashang guggulu might inhibit proteinase and lipoxygenase (enzymes that promote inflammation). However, further studies are required to check if trayodahsang guggulu may reduce inflammation. Therefore, you must consult your doctor if you suspect inflammation.  

4. Potential Use of Trayodashang Guggulu for Arthritis

Arthritis

Arthritis is a disease associated with inflammatory pain. Bioactive compounds like flavonoids and phenols present in trayodashang guggulu may be responsible for reducing inflammatory pain. A study3 by Gupta et al. in 2022 showed that trayodashang guggulu might inhibit inflammatory mediators like COX-2 and reduce inflammatory pain, which may be beneficial for arthritis. Inflammatory mediators are molecules in the body that cause inflammation. However. Further studies are required to check if trayodashang guggulu may be helpful in the case of arthritis. Therefore, you must consult your doctor if you experience any symptoms of arthritis.  

5. Potential Use of Trayodashang Guggulu for Sciatica

lower back

Sciatica refers to the pain radiating down one or both legs from the lower back along the sciatic nerve. According to the studies5 by Moharana et al. in 2018, trayodashang guggulu may be beneficial in the case of sciatica. Effects of trayodashang guggulu are particularly noticeable in vata dosha, the primary cause of joint and bone-related disorders3,7. However, further studies are required to check if trayodashang guggulu may be beneficial for sciatica. You must immediately consult your doctor if you suspect any symptoms of sciatica. 

6. Potential Use of Trayodashang Guggulu for Tennis Elbow

tennis elbow

The condition that causes pain in the forearm is known as the tennis elbow. Pain, tenderness, restricted movement, stiffness and diminished grip strength are the primary clinical signs of tennis elbow. The study6 by Rajurkar et al. in 2022 showed that the trayodashang guggulu tablet might reduce pain and functional disability related to the tennis elbow. However, further studies are required to check if trayodashang guggulu may be beneficial in the case of tennis elbow. Therefore, you must consult your doctor if you experience any symptoms of tennis elbow. 

7. Potential Use of Trayodashang Guggulu for Osteoporosis

bone health

Trayodashanga Guggulu may directly affect the Asthigata Vata (bone and soft tissue pain) and brings the vitiated Vata Dosha back into balance. An imbalance in vata dosha causes conditions related to joints and bones. The Ayurvedic mind-body element associated with air and space is called vata dosha. It governs all movement and processes in your mind and body, including blood flow, elimination, breathing and thought action. A Vata imbalance may lead to bone thinning, according to Ayurveda. Therefore, trayodashang guggulu may be beneficial in case of osteoporosis. This was shown by a study7 conducted by Sannakki et al. in 2020. However; further studies are required to check if trayodashang guggulu may be beneficial for osteoporosis. Therefore, you must consult your doctor if you experience any symptoms of osteoporosis. 

8. Potential Use of Trayodashang Guggulu for Enhancing the Immune System

Immunity

According to the study4 by Prasad et al. in 2016, trayodashang guggulu may help improve the immune system. It may have immune-modulating properties, which may stimulate the immune system. However, further studies are required to check if trayodashang guggulu may affect the immune system. 

Though studies show the benefits of trayodashang guggulu in various situations, these are insufficient and further studies are needed to establish the true extent of trayodashang guggulu on human health. 

How to Use Trayodashang Guggulu?

Trayodashang guggulu is a polyherbal ayurveda preparation that is available as a tablet. It can be given with gruel (thin porridge), warm water and milk of meat soup5

You must consult a doctor before taking large quantities of trayodashang guggulu or herbal supplements. Do not discontinue an ongoing modern medical treatment with an ayurvedic/herbal preparation without consulting a qualified doctor. 

Side Effects of Trayodashang Guggulu

A high dose of trayodashang guggulu may have the following side effects: 

You must consult your doctor if you experience any side effects after consuming trayodashang guggulu. 

Also Read: Nagkesar (Mesua Ferrea): Benefits, Uses, Side Effects & More!

Precautions to Take with Trayodashang Guggulu

As with any other general medicine, general precautions should be taken while having trayodashang guggulu. You must consult your doctor before having trayodashang guggulu. Pregnant women and lactating mothers should take special care. Precaution should be taken before giving trayodashang guggulu to the elderly or children. In such cases, you must have trayodashang guggulu only if your doctor prescribes it. 

Also Read: Licorice (Mulethi): Uses, Benefits, Side Effects, and More!

Interactions with Other Drugs

There is not enough evidence on the interaction of trayodashang guggulu with other drugs. Further studies on the interaction of trayodashang guggulu are required. Therefore, you must consult your doctor if you are on any other medication before consuming trayodashang guggulu. 

Also Read: Raisins (Kishmish): Uses, Benefits, Side Effects By Dr. Smita Barode

Frequently Asked Questions (FAQs)

What are the components of trayodashang guggulu?

Trayodashang guggulu is an essential Ayurvedic polyherbal formulation. It consists of Babula, Hapusa, Shatavari, Ashwagandha, Sunthi, Satavha, Vradadaru, Sati, Shuddha guggulu, Rasana, Guduchi, Gokshuara, Yavani and Goghrat (ghee)1

What are the health benefits of trayodashang guggulu? 

Trayodashang guggulu may be used to reduce pain and inflammation. It may act against the conditions like tennis elbow, arthritis, osteoporosis, sciatica and cervical spondylosis. It may have antioxidant properties and may enhance the immune system. However, further studies are required to check whether trayodashang guggulu may benefit the mentioned conditions. Therefore, you must consult your doctor if you experience symptoms of the mentioned conditions1,6

How can you consume trayodashang guggulu? 

Trayodashang guggulu is a polyherbal ayurveda preparation that is available as a tablet. It can be given with gruel (thin porridge), warm water and milk of meat soup4

What are the side effects of trayodashang guggulu? 

Trayodashang guggulu may cause stomach upset, belching, indigestion and loss of appetite. You must consult your doctor if you experience any side effects8

How is trayodashang guggulu beneficial for arthritis? 

Bioactive compounds like flavonoids and phenols present in trayodashang guggulu may be responsible for reducing inflammatory pain. They might inhibit inflammatory mediators (molecules in the body that cause inflammation) and reduce inflammatory pain, which may be beneficial for arthritis3. However, you must consult your doctor if you experience any symptoms of arthritis. 

References

  1. Dadoriya P, Dey YN, Sharma D, Yadav M, Wanjari MM, Gaidhani SN, Subhose V. In-vitro anti-inflammatory and antioxidant activities of an Ayurvedic formulation–Trayodashang guggulu. Journal of Herbal Medicine. 2020 Oct 1;23:100366. Available from: https://www.sciencedirect.com/science/article/pii/S2210803320300385 
  2. Rathod HS, Sawant RS. Evaluation of efficacy of Trayodashang guggulu in management of Cervical spondylosis (Manyagata vata). J Biol Sci Opin. 2013;1(2):65-9. Available from: https://www.researchgate.net/publication/315330757_EVALUATION_OF_EFFICACY_OF_TRAYODASHANG_GUGGULU_IN_MANAGEMENT_OF_CERVICAL_SPONDYLOSIS_MANYAGATA_VATA 
  3. Gupta S, Dey YN, Kannojia P, Halder AK, Sharma D, Wanjari MM, Chougule S, Pawar S, Kaushik A, Gaidhani SN, Gurav S. Analgesic and Anti-inflammatory Activities of Trayodashang Guggulu, an Ayurvedic Formulation. Phytomedicine Plus. 2022 Aug 1;2(3):100281. Available from: https://www.sciencedirect.com/science/article/pii/S2667031322000641
  4. Prasad R. Guggulu preparations: Gold standards in the management of Joint disorders. British Journal of Medical and Health Research. 2016 Jan. Available from: https://www.researchgate.net/publication/335716125_Guggulu_preparations_Gold_standards_in_the_management_of_Joint_disorders 
  5. Moharana PK, Patel A. Synergistic effect of Trayodashang Guggulu and yoga basti in the management of low back pain with special reference to Gridhrasi. Int J Health Sci Res. 2018;8:167-73. Available from: https://www.ijhsr.org/IJHSR_Vol.8_Issue.12_Dec2018/27.pdf 
  6. Rajurkar H, Misar S, Dandekar P, Kane S, Dawande P, Damahe LB. Assessment of comparative Efficacy of Nirgundipatra Upanaha and Trayodashang Guggulu with Diclofenac sodium Gel and Ibuprofen in the Management of Snayugata Vata Affecting Koorpara Sandhi (Tennis Elbow). Australasian Medical Journal. 2022 Feb 1;15(2). Available from: https://amj.net.au/index.php/AMJ/article/viewFile/3866/2018 
  7. Sannakki SY, Kalyani SS, MH M. Paryeshana International Journal of Ayurvedic Research. Available from: http://pijar.org/articles/Arch_Vol5_Issue5/13.Dr.Sumitkumar%20Y%20Sannakki.pdf 
  8. Sahiti M, Gurupadayya BM, Dinesh TK. Evaluation of in vitro anti-inflammatory activity of Trayodashang Guggulu: An ayurvedic formulation in comparison with allopathic drug. Int J Res Ayurveda Pharm. 2019;10(3):92-6. Available from: https://www.researchgate.net/publication/335188499_EVALUATION_OF_IN_VITRO_ANTI_INFLAMMATORY_ACTIVITY_OF_TRAYODASHANG_GUGGULU_-_AN_AYURVEDIC_FORMULATION_IN_COMPARISION_WITH_ALLOPATHIC_DRUGS 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any change

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Bilimbi: Uses, Benefits and Side Effects By Dr. Rajeev Singh

Introduction

Have you ever noticed a bright green flower-shaped segmented fruit growing on the trees? The fruit is called Bilimbi in English. The scientific name of bilimbi is Averrhoa bilimbi, which belongs to the Oxalidaceae family. It is known as blimblim in French, mimbro in Spanish, belimbing asam in Malay and kaling pring in Thai. Bililmbi fruits are often eaten raw, used to make wine, vinegar and pickles and substitute for tamarind in dishes and also be used as a flavouring agent. In Thailand, Malaya and Singapore, bilimbi is very common. It is frequently grown in gardens across the plains of India and thrives in all the country’s warmest regions. Bilimbi or Averrhoa bilimbi, is a folk remedy for many ailments1,2. Let us have a look at some of them. 

Did you know?

Nutritional Value of Bilimbi

Bilimbi may contain bioactive compounds like amino acids, citric acid, cyanidin–3–O–h–D–glucoside, phenolics and sugars2. Additionally, 100 gm ripened fruit of bilimbi may contain the following nutritional components: 

*unit is per 100g unless otherwise stated

Properties of Bilimbi

Several studies have shown that bilimbi may have the following properties3

Potential Uses of Bilimbi for Overall Health

Some of the potential uses of bilimbi are:

1. Potential Uses of Bilimbi for Liver Health 

liver

Bilimbi may help to improve liver health. The results of a study by Nagmoti et al. in 2010 suggested a significant increase in the activity of liver enzymes (SGOT, SGPT, ALP) and serum bilirubin levels. Increased levels of these enzymes may cause various liver diseases6. However, further studies are required to check if bilimbi can protect the liver. Therefore, you must consult your doctor if you have any symptoms of liver disease. 

2. Potential Uses of Bilimbi for Cancer 

cancer

Leaf extracts of bilimbi may have anticancer properties against breast cancer. Bioactive compounds like terpenoids, flavonoids, tannins and saponins may kill cancer-causing cells (apoptosis and programmed cell death) and inhibit the growth of cancer-causing cells (proliferation)7. However, further studies are required to check if bilimbi may help in the case of breast cancer. Cancer is a dangerous disease therefore, you must consult your doctor if you suspect any symptoms of cancer instead of self-medicating. 

3. Potential Uses of Bilimbi for Lowering Blood Sugar Levels 

diabeties

According to the study8 conducted in 2004 by Tan et al., bilimbi may be beneficial in the case of diabetes mellitus. Bilimbi may reduce blood glucose levels. However, further studies are required to check if bilimbi can be beneficial in the case of diabetes. Therefore, you must check your blood sugar levels regularly and consult your doctor in case of abnormal blood glucose levels instead of relying on bilimbi fruit. 

4. Potential Uses of Bilimbi for Lowering Cholesterol

cholesterol

Bilimbi may reduce bad cholesterol (LDL, VLDL) and increase good cholesterol levels (HDL) due to bioactive compounds like terpenoids, tannins, phenols and flavonoids. This was shown in a study9 conducted by Mohan et al. in 2016. However more studies are required to check if bilimbi can be beneficial for lowering cholesterol levels. Therefore, you must check your cholesterol levels regularly and consult your doctor in case of high cholesterol levels. Bilimbi is in no way a solution to high cholesterol. 

5. Potential Uses of Bilimbi for Lowering Blood Pressure 

hypertension

Flavonoids present in bilimbi may be responsible for lowering blood pressure, according to the studies conducted by Rafida et al. in 2021. The flavonoids may dilate the blood vessels and decrease the resistance to blood flow10. However, further studies are required to check if bilimbi is beneficial for lowering blood pressure. Therefore, you must check your blood pressure regularly and consult your doctor in case of high blood pressure. 

6. Other Potential Uses of Bilimbi

Bilimbi
Image Source: freepik.com

Though studies show the benefits of bilimbi in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of bilimbi on human health. 

Of all the traditional uses of bilimbi that I have seen, one notable application is making infusions and decoctions of its leaves. These may be used as a protective medicine after childbirth16.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Bilimbi?

You can use bilimbi in the following ways: 

You must consult a qualified doctor before taking bilimbi in large quantities or any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor 

Based on what I have noticed, the fruit juice of bilimbi is believed to have beneficial effects in addressing many health concerns. It has potentially been used in traditional remedies to manage various conditions such as whooping cough, scurvy, and even obesity16.

Dr. Rajeev Singh, BAMS

Side Effects of Bilimbi

A case study of a 65 year-old woman by Chiang et al. in 2020 showed that bilimbi might hamper the nervous system and show the following symptoms12:  

If you notice any reaction to consuming bilimbi, seek immediate medical attention. Consult your ayurvedic physician who has prescribed it to you; they will be able to identify the cause and treat it effectively. 

According to some literature I came across, a syrup made from bilimbi fruit is believed to have medicinal properties. It is taken as a potential remedy for fever and inflammation, and it is also used to address rectal bleeding and provide relief from internal haemorrhoids17.

Dr. Smita Barode, B.A.M.S, M.S.

Precautions to Take with Bilimbi

The following precautions should be taken before eating bilimbi: 

It is advised to consult your doctor before consuming bilimbi if you have any pre-existing diseases. 

Let me share an interesting observation. In Malaysia, people use either fresh or fermented bilimbi leaves for the management of venereal diseases, which are infections or conditions transmitted through sexual contact. It is a traditional remedy believed to be effective in addressing these specific health concerns18.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

Interactions with Other Drugs

Since not much data is available on the drug interactions with Bilimbi, let us know about the drug interactions of the fruits belonging to the genus of Bilimbi (Averrhoa). 

You must consult your doctor before consuming bilimbi if you are on any other medication. 

Also Read: Zucchini (Courgette): Uses, Benefits, Side effects and More!

Frequently Asked Questions (FAQs)

What are the health benefits of bilimbi for high blood pressure?

Bilimbi may dilate the blood vessels and decrease the resistance to blood flow. However, you must check your blood pressure regularly and consult your doctor in case of high blood pressure10.  

What are the side effects of bilimbi? 

Billimbi may cause uncontrollable hiccups, mental confusion and seizures12. In case you notice a reaction after consuming bilimbi, seek immediate medical attention. 

What precautions should be taken before consuming bilimbi? 

People with chronic kidney disease should be careful before consuming bilimbi13. Due to high levels of oxalates, bilimbi may lead to kidney stones12. You should consult your doctor before consuming bilimbi if you have any pre-existing diseases like kidney disorders. 

How can you consume bilimbi? 

Fresh fruit of bilimbi can be eaten raw. Pounded fresh bilimbi leaves yield juice through squeezing, which is provided once daily11. You must consult a qualified doctor before taking bilimbi in large quantities and do not replace your ongoing treatment. 

What are the benefits of bilimbi for diabetes? 

Bilimbi may be beneficial in the case of diabetes mellitus as it may reduce blood glucose levels8. However, you must check your blood sugar levels regularly and consult your doctor in case of abnormal blood glucose levels. 

References

  1. Rymbai H, Deshmukh N, Anjani K, Patel RS & Paul, Debanjoy P, Patel V. BILIMBI (Averrhoa bilimbi L.). 2019 Aug. Available from: https://www.researchgate.net/publication/335240608_BILIMBI_Averrhoa_bilimbi_L 
  2. Kumar KA, Gousia SK, Anupama MA, Latha JN. A review on phytochemical constituents and biological assays of Averrhoa bilimbi. Int J Pharm Pharm Sci Res. 2013;3(4):136-9. Available from: https://www.researchgate.net/profile/Jeevigunta-Naveena-Lavanya-Latha/publication/322701172
  3. Alhassan AM, Ahmed QU. Averrhoa bilimbi Linn.: A review of its ethnomedicinal uses, phytochemistry and pharmacology. Journal of pharmacy & bioallied sciences. 2016 Oct;8(4):265. Available from: https://www.researchgate.net/publication/313223217_
  4. Mackeen MM, Ali AM, El-Sharkawy SH, Manap MY, Salleh KM, Lajis NH, Kawazu K. Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (ulam). International Journal of Pharmacognosy. 1997 Jan 1;35(3):174-8. Available from: researchgate.net/publication/250188196_Antimicrobial_and_Cytotoxic_Properties_of_Some_Malaysian_Traditional_Vegetables_Ulam?__cf_chl_tk=bV2oCPJAazeowOT1FSrtDh6gL54bmIUfuGuJkMplEBI-1769150960-1.0.1.1-KnoFVl.gs0OrYfC_eRS5y8GMo9y.U4CDmk4r9CSx2_8
  5. Iwansyah AC, Desnilasari D, Agustina W, Pramesti D, Indriati A, Mayasti NK andriana Y, Kormin FB. Evaluation on the physicochemical properties and mineral contents of Averrhoa bilimbi L. leaves dried extract and its antioxidant and antibacterial capacities. Food Science and Technology. 2021 Mar 8;41:987-92. Available from: https://www.researchgate.net/publication/349911890_Evaluation_on_the_physicochemical_properties_and_mineral_contents_of_Averrhoa_bilimbi_L_leaves_dried_extract_and_its_antioxidant_and_antibacterial_capacities/fulltext/6049c1a792851c1bd4df11f8/Evaluation-on-the-physicochemical-properties-and-mineral-contents-of-Averrhoa-bilimbi-L-leaves-dried-extract-and-its-antioxidant-and-antibacterial-capacities.pdf
  6. Nagmoti DM, Yeshwante SB, Wankhede SS, Juvekar AR. Hepatoprotective effect of Averrhoa bilimbi Linn. against carbon tetrachloride induced hepatic damage in rats. Pharmacologyonline. 2010;3:1-6. Available from: https://www.researchgate.net/profile/Shekhar-Yeshwante/publication/265401741
  7. Nair MS, Soren K, Singh V, Boro B. Anticancer activity of fruit and leaf extracts of Averrhoa bilimbi on mcf-7 human breast cancer cell lines: a preliminary study. Austin J Pharmacol Ther. 2016;4(2):1082. Available from: https://austinpublishinggroup.com/pharmacology-therapeutics/fulltext/ajpt-v4-id1082.php
  8. Tan BK, Tan CH, Pushparaj PN. Anti–diabetic activity of the semi–purified fractions of Averrhoa bilimbi in high fat diet fed–streptozotocin–induced diabetic rats. Life sciences. 2005 Apr 29;76(24):2827-39. Available from: https://www.sciencedirect.com/science/article/pii/S0024320505000743 
  9. Arya MK, Mohammed SP, Ganesan PS. In vitro hypolipidemic activity of Averrhoa bilimbi flower extract. The Pharma Innovation. 2016 Oct 1;5(10, Part A):23. Available from: https://www.thepharmajournal.com/archives/2016/vol5issue10/PartA/5-9-13-584.pdf 
  10. Rafida M, Safitri AH, Tyagita N. Effect of Averrhoa bilimbi Fruit Extract on Blood Pressure and Mean Arterial Pressure of NaCl Induced Hypertensive Rats. Bangladesh Journal of Medical Science. 2021 Apr 4;20(3):631-6. Available from: researchgate.net/publication/368023488_Effect_of_Averrhoa_bilimbi_Fruit_Extract_on_Blood_Pressure_and_Mean_Arterial_Pressure_of_NaCl_Induced_Hypertensive_Rats?_share=1
  11. Ediriweera ER, Ratnasooriya WD. A review on herbs used in treatment of diabetes mellitus by Sri Lankan ayurvedic and traditional physicians. Ayu. 2009 Oct 1;30(4):373-91. Available from: https://www.researchgate.net/publication/285706172_A_review_on_herbs_used_in_treatment_of_diabetes_mellitus_by_Sri_Lankan_Ayurvedic_and_traditional_physicians
  12. Chiang M, Yabut MR. Is Excessive Intake of Kamias Fruit (Averrhoa bilimbi) Bad for Your Heath? A Case Report and Review. International Journal of Clinical Case Reports and Reviews. 2020;3(5). Available from: https://pdfs.semanticscholar.org/bfe9/b281e69909ee69388cc93351ab48bee63e15.pdf 
  13. Wong KW, Lansing MG. Case of acute kidney injury due to bilimbi fruit ingestion. BMJ Case Reports CP. 2021 Jul 1;14(7):e242325. Available from: https://casereports.bmj.com/content/bmjcr/14/7/e242325.full.pdf 
  14. Product monograph – s3.pgkb.org [Internet]. [cited 2023Feb1]. Available from: https://s3.pgkb.org/attachment/Bosutinib_HCSC_07_29_15.pdf 
  15. Faridak panobinostat capsules, for oral use [Internet]. [cited 2023Feb1]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/205353s000lbl.pdf 
  16. Alhassan AM, Ahmed QU. Averrhoa bilimbi Linn.: A review of its ethnomedicinal uses, phytochemistry, and pharmacology. J Pharm Bioallied Sci. 2016 Oct-Dec;8(4):265-271. doi: 10.4103/0975-7406.199342. PMID: 28216948; PMCID: PMC5314823. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5314823/
  17. Roy A, RV G, Lakshmi T. Averrhoa bilimbi Linn–Nature’s drug store: a pharmacological review. Int J Drug Dev Res. 2011;3(3):101–106. Available from: https://www.ijddr.in/drug-development/averrhoa-bilimbi-linnnatures-drug-store-a-pharmacologicalreview.pdf
  18. Mehta R, Sharma P, Gupta J. A review on ethnopharmacology and methodology of cream: Averrhoa bilimbi. International Journal of Creative Research Thoughts (IJCRT). 2023 Mar;11(3):496–513. Available from: https://ijcrt.org/papers/IJCRT2303278.pdf

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Jackfruit Seed: Uses, Benefits and Side Effects By Dr. Rajeev Singh 

Introduction

Jackfruit is the largest tree fruit that gained popularity due to its sweet, fleshy and energy-rich pulp. The exterior of jackfruit is hard green or yellow initially and turns to yellowish brown after ripening. The inner edible flesh of the jackfruit consists of nutritious pulp coated around the seed, formed by the fusion of flowers. Jackfruit is a non-seasonal fruit that grows on evergreen trees in tropical areas. The biological name of the jackfruit tree is Artocarpus heterophyllus Lam, belonging to the family Moraceae. It is cultivated in Bangladesh, Sri Lanka, Malaysia and various parts of Southeast Asia, Africa and America. Jackfruit grows abundantly in India and is native to the Western Ghats of India1,2

Apart from the flesh, jackfruit seeds are also edible and are used in cooked dishes. The jackfruit seeds with a thin brown seed coat, known as spermoderm, are enclosed in a white layer. The brown spermoderm consists of white cotyledon rich in protein and starch. Jackfruit seed has a lot of potential benefits, especially in the cosmetics, paper, pharmaceutical and bio-nanotechnology industries2.

Did you know?

Nutritional Value of Jackfruit Seed

The nutrient value of jackfruit seed is as under: 

Properties of Jackfruit Seed

Potential Uses of Jackfruit Seed for Overall Health

The potential health benefits of jackfruit seed are: 

1. Potential Uses of Jackfruit Seed for Strengthening Bones 

Magnesium is a mineral crucial for body functioning and keeps our bones strong by absorbing calcium in bones. Calcium makes our bones strong and rigid and allows normal body movement. Swami et al., 2012 presented an overview of the functional and medicinal value of Jackfruit. They mentioned that jackfruit seeds are rich in magnesium, which may help in the absorption of calcium in the bones. Magnesium, along with calcium, strengthens bones and relieves disorders related to bones, e.g. osteoporosis (weak and brittle bones). Thus, it is suggested that jackfruit seeds may have potential benefits in strengthening the bones. Further studies should be conducted to validate the efficacy of jackfruit seeds2.  

2. Potential Uses of Jackfruit Seed as an Antioxidant 

Antioxidants are agents that reduce the effects of free radicals responsible for chronic health problems. Ranasinghe et al. in 2019 mentioned that jackfruit seeds possess a good amount of ascorbic acid and gallic acid which may protect the body from the negative effects of excess free radical production thus promoting antioxidant activity. Therefore, it can be concluded that jackfruit seeds may help in contributing to the antioxidant activity. More data is required to establish the true extent of its benefit on human health1.

3. Potential Uses of Jackfruit Seed as an Antibacterial Agent 

Mahanta et al., 2015 and Ranasinghe et al., 2019 mention that the jackfruit seeds extract has shown efficacy against S.aureus, E. coli and B. megaterium revealing that jackfruit seed may have some antimicrobial effects. It may be used to formulate pharmaceutical agents for infectious diseases. Jackfruit seed powder may also help against food contamination. Thus, the seeds of jackfruit may have the potential as an antibacterial agent. Further research should be conducted to validate the efficacy of jackfruit seeds1,3.  

4. Potential Uses of Jackfruit Seed as an Antidiabetic Agent 

Dwitiyanti et al., 2019 conducted a study on pregnant female rats. The jackfruit seed extract was administered to diabetic pregnant female rats. The blood glucose levels of pregnant female rats decreased after the administration of jackfruit seed extracts. Therefore, it is suggested that the jackfruit seed extract possesses activities that may have the potential of decreasing blood sugar levels. Further clinical research is required to investigate the true benefit of jackfruit seed in human health5

5. Other Potential Uses

Though there are studies that show the benefits of jackfruit seed in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of jackfruit seed on human health.  

Due to their high fibre content, I’ve experienced that jackfruit seeds may help reduce the risk of heart disease, avoid constipation, and may aid in weight reduction. They are also a good source of B-complex vitamins. Additionally, resistant starch, which may regulate blood sugar and may maintain intestinal health, is included in jackfruit seeds6.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Jackfruit Seed?

You must consult a qualified doctor before taking any jackfruit seed supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Additionally, the researchers have found that the seeds have an abundance of highly soluble protein that may aid in the management of anxiety and stress6.

Dr. Rajeev Singh, BAMS

Side Effects of Jackfruit Seed

The most common side effects related to jackfruit seed are: 

Also Read: Jackfruit (Kathal): Uses, Benefits, Side Effects and More!

Precautions to Take with Jackfruit Seed

Patients suffering from digestive disorders must consult their physician before consuming jackfruit seeds. Though, there is not much data available on the consumption of jackfruit seeds during pregnancy and breastfeeding. Thus, lactating and pregnant females should ask their gynaecologist before consuming jackfruit seeds. The elderly and children should also consume jackfruit seeds in moderation if necessary and consult a physician if suffering from any health-related disorders. 

In my experience, the seeds have a very poor capacity to absorb water and fat. Hence, it may aid in maintaining a healthy weight6.

Dr. Smita Barode, B.A.M.S, M.S.

Also Read: Lotus Seed: Uses, Benefits, Side Effects and More By Dr. Smita Barode

Interactions with Other Drugs

No interactions are reported in the literature reviewed. If you are on medication, consult an experienced and qualified doctor before taking any jackfruit seed supplements. This can possibly help in avoiding interaction with other medicines. 

Also Read: Hemp Seed: Uses, Benefits and Side Effects by Dr. Smita Barode

Frequently Asked Questions (FAQs)

Is jackfruit seed edible?  

The seed of jackfruit contains a high amount of protein and other vitamins and minerals, which adds to its nutritional value. Thus, jackfruit seed is edible and is used as a nutritious source of food.  

How are jackfruit seeds used? 

Jackfruit seeds are used after boiling, roasting or cooking. The seeds are boiled in sugar water to serve as a dessert. It may also be used as an ingredient in vegetables and curries in Asian dishes.  

What are the benefits of jackfruit seeds? 

The jackfruit seeds may serve a potential in human health and may benefit as an antimicrobial, antidiabetic and antioxidant. It may also provide benefits in strengthening the bones. It may also be used as a substitute to flour with an increase in protein and fibre content. 

Who should avoid eating jackfruit seeds? 

The patients suffering from digestive disorders must avoid consuming jackfruit seeds. Elderly, children and pregnant and lactating females should consult the doctor before taking jackfruit seeds in any form. 

How is jackfruit seed flour used? 

The flour of jackfruit seed may be used in various bakeries and biscuit factories to make cookies. It might also be used as binding and thickening agent in various food industries. 

References

  1. Ranasinghe RA, Maduwanthi SD, Marapana RA. Nutritional and health benefits of jackfruit (Artocarpus heterophyllus Lam.): a review. International journal of food science. 2019 Jan 6;2019. Available form: https://www.hindawi.com/journals/ijfs/2019/4327183/  
  1. Swami SB, Thakor NJ, Haldankar PM, Kalse SB. Jackfruit and its many functional components as related to human health: a review. Comprehensive Reviews in Food Science and Food Safety. 2012 Nov;11(6):565-76. Available form : https://ift.onlinelibrary.wiley.com/doi/abs/10.1111/j.1541-4337.2012.00210.x  
  1. Mahanta CL, Kalita D. Processing and utilization of jackfruit seeds. InProcessing and impact on active components in food 2015 Jan 1 (pp. 395-400). Academic Press. Available form: https://www.sciencedirect.com/science/article/pii/B9780124046993000470  
  1. Waghmare R, Memon N, Gat Y, Gandhi S, Kumar V, Panghal A. Jackfruit seed: an accompaniment to functional foods. Brazilian Journal of Food Technology. 2019 Jun 13;22. Available form: https://www.scielo.br/j/bjft/a/5yY7zY6RXVSQQFgnPyKtTqj/abstract/?lang=en  
  1. Dwitiyanti D, Rachmania RA, Efendi K, Septiani R, Jihadudin P. In Vivo Activities and In Silico Study of Jackfruit Seeds (Artocarpus heterophyllus L.am.) on the Reduction of Blood Sugar Levels of Gestational Diabetes Rate Induced by Streptozotocin. Open Access Macedonian Journal of Medical Sciences. 2019 Nov 30;7(22):3819. Available form: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048328/  
  2. Waghmare R, Memon N, Gat Y, Gandhi S, Kumar V, Panghal A. Jackfruit seed: an accompaniment to functional foods. Brazilian Journal of Food Technology [Internet]. 2019 [cited 2025 Oct 9];22:e2018207. Available from: https://www.scielo.br/j/bjft/a/5yY7zY6RXVSQQFgnPyKtTqj/?lang=en#:~:text=The%20seeds%20are%20rich%20in,and%20keeps%20the%20gut%20healthy.

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Phalsa fruit (Grewia asiatica): Uses, Benefits, and Side Effects By Dr. Smita Barode 

Introduction

“With the changing times, not only the country’s policymakers but the whole world is realising the importance of Ayurveda. Who would’ve thought that people in the upcoming generations would prefer a bottle of gooseberry or bottle gourd juices over carbonated drinks?” Despite this realization of the health benefits of plants and fruits, there are fruits like Phalsa which, although are high in nutrients but low in popularity. Phalsa is a plant that originates in Southeast Asian countries like India, Nepal, Sri Lanka and Bangladesh and is mainly grown for its fruit. The scientific name of the Phalsa fruit is Grewia asiatica, also known as the Indian Sherbet berry. It is a seasonal plant and the fruits are generally obtained in the summer. Phalsa fruit resembles grapes in its shape and size. They are purple in colour with a sour-sweet taste. The fruit is a powerhouse of vitamins and minerals and offers many health benefits; let us know more about those benefits1

Nutritional Value of Phalsa Fruit

Phalsa fruit is rich in carbohydrates, fibres, proteins, vitamins A, B3 and C and minerals like potassium, calcium, iron and phosphorus. The phytochemicals present in Phalsa fruit include anthocyanins, tannins, phenols and flavonoids. The nutritional chart of this fruit is given below.  

Properties of Phalsa Fruit

Phalsa fruit shows numerous scientifically proven properties; some of which are mentioned below1

I’ve discovered that Phalsa fruits have a cooling effect on the body. Phalsa fruit is rich in phenols. This property makes it a potential natural remedy for excessive body heat9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Phalsa Fruit for Overall Health

Some of the potential benefits of Phalsa fruit are described below. 

1. Potential Use of Phalsa Fruit in Diabetes

diabetes

Diabetes (Type I & II) is characterised by an increase in blood glucose due to a reduction or resistance to insulin (a hormone that regulates blood glucose). Literature shows that fruits rich in polyphenols may positively impact diabetes. Parveen et al. conducted a study2 on diabetic rabbits in 2013 to assess the effect of Phalsa fruit on blood glucose. This study showed a reduction in rabbits’ blood glucose after administering Phalsa fruit. Additionally, this fruit has a low glycemic index and the presence of polyphenols may help reduce blood glucose levels. This indicates that Phalsa fruit may help manage diabetes. However, to claim these results in humans, we need more studies. It is further advised not to self-medicate and consult your physician for proper management of diabetes3

2. Potential Uses of Phalsa Fruit in Dyslipidemia

cholesterol

Dyslipidemia is characterised by an increase in total cholesterol and triglycerides. Studies have shown that Phalsa fruit may potentially control the altered parameters in dyslipidemia. An animal study4 conducted by Parveen et al. in 2013 showed a positive relationship between the consumption of this fruit and lipid levels. Rabbits administered Phalsa fruit extract (200mg/kg) showed reduced total cholesterol and triglycerides. This may indicate that this fruit’s consumption may help manage dyslipidemia. However, more studies on humans are needed to support these claims. Additionally, it is advised not to rely on Phalsa fruit as a remedy for managing dyslipidemia and kindly consult your physician for the proper management of dyslipidemia. 

3. Potential Uses of Phalsa Fruit in Breast Cancer

breast cancer

Breast cancer is one of the most common cancers affecting women worldwide; different ayurvedic treatments are being tested for their effectiveness towards breast cancer. A review2 by Muhammed et al. in 2013 states that Phalsa fruit contains smart molecules called anthocyanins which help reduce the multiplication of abnormal cells and the risk of cancers. Thus, it may be concluded that Phalsa fruit may reduce breast cancer risk. However, we need more human studies to claim these results accurately. Also, it is advised not to consider Phalsa fruit as an alternative to modern medicine; you should always consult your doctor for proper management of breast cancer. 

4. Potential Uses of Phalsa Fruit as an Antibacterial Agent

phalsa fruit

Traditionally, herbs, spices, leaves and fruits obtained from plants were used for managing bacterial infections. Muhammed et al. conducted a review2 in 2013 to test the efficacy of Phalsa fruit on different bacteria. The presence of polyphenols in Phalsa fruit inhibited the growth of S.typhi bacteria; thus, it may have the potential to manage bacterial infections like Typhoid caused by S.typhi bacteria. However, we need more studies to confirm these results in humans. Additionally, you should not consider Phalsa fruit as a remedy for managing Typhoid; it is always advised to consult a physician for proper management of Typhoid. 

5. Potential Uses of Phalsa Fruit in Depression

stress

Depression is a mood disorder that results in sadness and loss of interest and may affect everyday activities. Previous studies have shown that healthy nutrition may help in managing various ailments. A study4 conducted by Imran et al. in 2021 stated that Phalsa fruit, due to the presence of antioxidants like phenols, anthocyanins, flavonoids, etc., may help in managing depression. Additionally, this fruit can potentially reduce anxiety (anxiolytic effect). Therefore, Phalsa fruit may have the potential to manage depression. To claim these results for humans, we need more studies. It is further advised not to consider Phalsa fruit as an alternative to modern medicine; kindly consider your doctor for proper management of depression5

6. Other Potential Uses of Phalsa Fruit

digestion problems

Though there are studies that show the benefits of Phalsa fruit in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of Phalsa fruit on human health.  

Let me give you a tip! Phalsa fruit might take care of your skin. Phalsa fruit is rich in antioxidants and numerous vitamins and minerals, which makes Phalsa a potential contributor to achieving flawless skin10.

Dr. Rajeev Singh, BAMS

How to Use Phalsa Fruit?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Phalsa Fruit

Phalsa fruit is considered safe when eaten in minimal amounts. A few side effects related to the consumption of Phalsa fruit include: 

However, if you experience any adverse reactions to Phalsa fruit, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Also Read: Mango (Aam): Uses, Benefits, Side Effects by Dr. Smita Barode

Precautions to Take with Phalsa Fruit

Consuming Phalsa fruit is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions1

Also Read: Hadjod (Cissus Quadrangularis): Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Phalsa fruit with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking. 

Also Read: Shallaki (Boswellia serrata): Uses, Benefits, Side Effects & More!

Frequently Asked Questions (FAQs)

What does Phalsa fruit look like? 

Phalsa fruit resembles grapes in its shape and size. They are purple in colour and sour to sweet in taste1.

What is the scientific name of Phalsa fruit? 

Phalsa fruit is called Grewia asiatica1. 

What is Phalsa fruit in Hindi? 

In Hindi, Phalsa fruit is called Sherbet berry.

Does the Phalsa fruit benefits weight loss? 

No, there are no proven results on the efficacy of the Phalsa fruit for reducing weight.

Is it okay to eat Phalsa fruit during pregnancy? 

The safety of Phalsa fruit consumption in pregnancy is not well-established; it is therefore advised to consult your doctor if you plan to add Phalsa fruit to your diet. 

References

  1. Mehmood, Arshad et al. “Nutraceutical perspectives and value addition of phalsa (Grewia asiatica L.): A review.” Journal of food biochemistry vol. 44,7 (2020): e13228. doi:10.1111/jfbc.13228. available at: https://pubmed.ncbi.nlm.nih.gov/32320069/ 
  2. Muhammad et al. “Grewia asiatica L., a food plant with multiple uses.” Molecules (Basel, Switzerland) vol. 18,3 2663-82. 28 Feb. 2013, doi:10.3390/molecules18032663. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270019/ 
  3. Khattab, Hala A H et al. “Antihyperglycemic Potential of Grewia asiatica Fruit Extract against Streptozotocin-Induced Hyperglycemia in Rats: Anti-Inflammatory and Antioxidant Mechanisms.” Oxidative medicine and cellular longevity vol. 2015 (2015): 549743. doi:10.1155/2015/549743. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542021/ 
  4. Imran et al. “Grewia asiatica Berry Juice Diminishes Anxiety, Depression and Scopolamine-Induced Learning and Memory Impairment in Behavioral Experimental Animal Models.” Frontiers in nutrition vol. 7 587367. 15 Jan. 2021, doi:10.3389/fnut.2020.587367. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844311/ 
  5. Chand, Suma P. and Hasan Arif. “Depression.” StatPearls, StatPearls Publishing, 18 July 2022. Available at: https://pubmed.ncbi.nlm.nih.gov/28613597/ 
  6. Khan, Rao & Asghar, Waqas & Khalid, Nauman & Nazir, Wahab & Farooq, Muhammad & Ahmed, Iftikhar & Syed, Qamar Abbas. (2019). Phalsa (Grewia asiatica L) fruit berry a promising functional food ingredient: A comprehensive review. Journal of Berry Research. 9. 10.3233/JBR-180332. Available at: https://www.researchgate.net/publication/329936198_Phalsa_Grewia_asiatica_L_fruit_berry_a_promising_functional_food_ingredient_A_comprehensive_review 
  7. Chung, K T et al. “Tannins and human health: a review.” Critical reviews in food science and nutrition vol. 38,6 (1998): 421-64. doi:10.1080/10408699891274273. Available at: https://pubmed.ncbi.nlm.nih.gov/9759559/ 
  8. Skibola, C F and M T Smith. “Potential health impacts of excessive flavonoid intake.” Free radical biology & medicine vol. 29,3-4 (2000): 375-83. doi:10.1016/s0891-5849(00)00304-x. Available at: https://pubmed.ncbi.nlm.nih.gov/11035267/ 
  9. Sivakumar D, Sultanbawa Y, Netzel M, editors. Handbook of Phytonutrients in Indigenous Fruits and Vegetables. CABI; 2022. P. 390. Available from: https://books.google.co.in/books?hl=en&lr=&id=vFacEAAAQBAJ&oi=fnd&pg=PA390&dq=phalsa+fruit+medicinal+uses&ots=rVQOJWvYfP&sig=Vz0jO1LIB6RpAMcHA-VCfL6a-eY&redir_esc=y#v=onepage&q=phalsa%20fruit%20medicinal%20uses&f=false
  10. Hassan H, Amin M, Rajwana IA, Ullah S, Razzaq K, Faried HN, et al. Nutritional functions and antioxidative enzymes in juice extract from two different maturity stages of low temperature stored phalsa (Grewia subinaequalis D.C.) fruit. LWT – Food Science and Technology. 2022;153:112552. Available from: https://www.sciencedirect.com/science/article/pii/S0023643821017059

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Gandhak Rasayan: Uses, Benefits, Side Effects and More!

Introduction

Gandhak Rasayan is a herbal medicine, known as Moringa ovalifolia in various botanical sources.  The formulations made from Gandhaka are referred to as Gandhaka Kalpas, where Gandhak in English refers to sulfur and Kalpas refers to medicinal preparation. It is used as a rejuvenator in Ayurveda, which promotes positive health and immunity. The increase in immunity helps the human body to resist various diseases. This property of Gandhak Rasayan also makes it a prophylactic agent (an agent that prevents disease) along with a therapeutic agent.  

According to ancient scholars, it is known as “Balivas”, as the king of Bali uses this very attractive sulfur internally to gain more power. Also, if Gandhak is combined with mercury, it transforms into a substance capable of eliminating diseases, known as murcchita state. Thus, gandhak based preparation has widespread clinical use and therefore, holds an important place in ayurvedic pharmaceutics1,3.

Nutritional Value of Gandhak Rasayan

Properties of Gandhak Rasayan

The properties of Gandhak Rasayan are: 

Potential Uses of Gandhak Rasayan for Overall Health

Gandhak Rasayan vati (tablet) and Gandhak Rasayan powder possess various health benefits. Some of its potential benefits are: 

1. Potential Uses of Gandhak Rasayan for Eczema

Clinical trials conducted by Sachin et al., 2017 to investigate the role of Gandhak Rasayan vati in Shushka Vicharchika (Eczema) exhibited good clinical improvement in terms of relieving individual symptoms as well as reducing the severity of the disease. Significant reduction in Daha, Kandu (itching), Ruja (sickness), and Sparshasahatva (burning sensation) was observed. Thus, it might be an effective solution for eczema6

2. Potential Uses of Gandhak Rasayan as an Antimicrobial Agent

infection

Gandhak Rasayan is considered a wide-spectrum antimicrobial agent with anti-fungal and anti-bacterial properties.  Various physicians recommend Gandhak Rasayan vati for the treatment of fungal or viral infection because of its bigger zone of inhibition with fewer side effects and comparatively low cost. The clinical efficacy of Gandhak Rasayan in non-infective post-operative cases was assessed by Kadam et al., 2022. This study2 revealed that various microorganisms that presented resistance to certain tested antibiotics showed good susceptibility to the Gandhak Rasayan. Therefore, Gandhak Rasayan is a versatile ayurvedic medicine that has a wide range of health-benefiting effects. 

3. Potential Uses of Gandhak Rasayan in Infections

skin infections

In a case study, the patient suffering from kushta (Tinea corporis) was treated with Gandhaka Rasayan along with exterior and interior applications of a combination of various oils and vati for 14 days. It has antifungal and antibacterial qualities. It mostly influences Rakta Dhatu and results in Rakta shodhan (purification of blood). Due to its antifungal qualities, it aids in decreasing infection. Additionally, it functions as a rasayan and aids in digestion and skin complexion improvement. Skin problems are treated with sulfur both orally and topically5

4. Potential Uses of Gandhak Rasayan in Vulvitis

Sulpher

Vulvitis is the inflammation of the vulva (soft folds of skin outside the vagina) which can result either from injuries, infection, allergy, or irritants. Verma and his colleague, 2021 evaluated the efficacy of Gandhak Rasayan lotion mixed with Gomutra arka, suddha Tankan in an effective and palatable management of vulvitis.  It was advised to apply lotion on the affected area after the bath for 10 minutes and wash with lukewarm Triphala. The treatment was continued for 15 days in two consecutive months. The results demonstrate a little reduction in the primary vulvitis symptoms and the patches of redness or swelling caused by vulvitis also effectively faded after therapy. Thus, concluding that Gandhak Rasayan may have some potential in the management of vulvitis7

5. Potential Uses of Gandhak Rasayan for Ulcerative Skin Lesions

skin itchiness

Gandhak Rasayan may also help in patients with complications such as ulcerative skin lesions over the legs, hands, and back. A similar case was treated with Gandhak Rasayan tablet (125mg), BD for 15 days, by Dr Dhodapkar in 2018. Patient with discharge and pruritis along with pedal oedema and ulcerative skin lesions. Gandhak Rasayan was prescribed for the reduction of infection and healing of skin lesions. It showed a significant reduction in oedema and partial healing of skin lesions in around 15 days8

I recently read an article which says the use of Gandhak Rasayana may aid in relieving the symptoms of arthritis. Gandhak Rasayana is known for its rejuvenating and anti-inflammatory properties9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

6. Other Potential Uses of Gandhak Rasayan Include

Sulpher

Though there are studies that show the benefits of the herb in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of Gandhak Rasayan on human health.  

How to Use Gandhak Rasayan?

Gandhak Rasayan is used in tablet form for the management and potential treatment of various diseases8. It may also be used in the form of topical agents like lotions mixed with other herbal medicines to treat skin disorders7. Gandhak Rasayan is also used as a powder with different herbal juices2.   

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Gandhak Rasayan

The most common Gandhak Rasayan side effects are loose stools, upset stomach, abdominal cramps, and bloating2. The histopathological analysis of rat models administered with repeated doses of Gandhak Rasayan showed mild hemorrhage in the Kidneys of rats along with mild fatty liver1

In my experience, Gandhak Rasayana may be used to delay the premature greying of hair. Gandhak Rasayana has a proven rejuvenator property10.

Dr. Rajeev Singh, BAMS

Precautions to Take with Gandhak Rasayan

Since there is insufficient information available on the safety and efficacy of Gandhak Rasayan during pregnancy and breastfeeding, it is best to avoid this rasayan in these groups2.  

Interactions with Other Drugs

Though there is no information on the interaction of gandhak rasayan with other drugs, some medications should never be combined.  If you’re using any other prescription or nonprescription (over-the-counter [OTC]) medication, consult your doctor before taking it. 

Also Read: Kalmegh: Uses, Benefits, Side Effects, Precautions & More!

Frequently Asked Questions (FAQs)

What are the side effects of Gandhak Rasayan? 

The side effects of Gandhak Rasayan include loose stool, abdominal cramps, upset stomach, and bloating. Fatty liver and kidney hemorrhage are also some other side effects reported in preclinical studies. 

What are the benefits of Gandhak Rasayan? 

Gandhak Rasayan may help in relieving pain, managing diabetes, respiratory and skin disorders along treating allergies. It may also act as an appetizer and rejuvenator. Gandhak Rasayan may also help in building immunity and positive health. 

Is Gandhak Rasayan safe during pregnancy? 

It is mostly advised to avoid Gandhak Rasayan during pregnancy and lactation. One should always consult a medical health practitioner before taking any herbal drugs. 

What does Gandhak Rasayan consist of? 

Gandhak Rasayan consists of sulfur, cow milk, cinnamon, amala, cardamom, patra, guduchi, vibhitaki, haritaki, shunto, and bringharaj along with sugar and water. 

What are the available forms of Gandhak Rasayan? 

It is available as Gandhak Rasayan powder, which can be formulated as Gandhak Rasayan vati (tablet) and as a topical lotion for skin disorders.  

References

  1. Mundugaru R, Ballal SR, Bhat S, Basavaiah R. Chronic toxicity studies of gandhaka rasayan-A herbo-mineral preparation used in Ayurvedic practice. Journal of Ayurveda and Integrative Medicine. 2021 Oct 1;12(4):673-81. Available from: https://www.sciencedirect.com/science/article/pii/S0975947621001054
  1. Kadam RV, Tajane SG. A clinical study of gandhak rasayan and triphala mashi with reference to anti-microbial agents. Available from:  https://www.researchgate.net/publication/362931598  
  1. Gandhaka, Gamdhaka: 20 definitions,Wisdom library. [Internet] Last updated: 31 December, 2022. [Cited: 2023 Jan 17] Available from: https://www.wisdomlib.org/definition/gandhaka  
  1. M.V.R.Wijayanthamala, Sanjay Kumar, Sarvesh Kumar Sing, B.R. Meena. Pharmaceutico-Analytical Study of Gandhaka Rasayan. International Journal of Ayurveda and Pharma Research. 2016;4(7):78-88. Available  form: https://www.researchgate.net/publication/341130665_PHARMACEUTICO-ANALYTICAL_STUDY_OF_GANDHAKA_RASAYAN?enrichId=rgreq-8cc9ef741fdc37f3ff109f27b2282e94-XXX&enrichSource=Y292ZXJQYWdlOzM0MTEzMDY2NTtBUzo4ODc0NjQzMDI1MDE4OTVAMTU4ODU5OTM4NjYwOQ%3D%3D&el=1_x_2&_esc=publicationCoverPdf   
  1. Chavhan MH, Wajpeyi SM. Management of Dadru Kushta (Tinea corporis) through Ayurveda–A Case Study. International Journal of Ayurvedic Medicine. 2020;11:120-23. Available from: https://www.researchgate.net/profile/Sadhana-Misar-Wajpeyi/publication/344645918_Management_of_Dadru_Kushta_Tinea_corporis_through_Ayurveda-_A_Case_Study/links/5fbb8056a6fdcc6cc65c98ca/Management-of-Dadru-Kushta-Tinea-corporis-through-Ayurveda-A-Case-Study.pdf  
  1. Sachin PK, Dattatray PV, Madhav PS. Role of Gandhak Rasayan in Shushka Vicharchika (eczema). AYUSHDHARA. 2016;4(3):1207-10.Available from: https://core.ac.uk/download/pdf/333809946.pdf  
  1. Anjali AV. A Pilot Study on Ayurveda Management of Vulvitis. Journal of Ayurveda and Holistic Medicine (JAHM). 2021 Sep 4;9(4). Available from:  http://www.jahm.co.in/index.php/jahm/article/view/449
  2. Dhodapkar SP, Kale AB. Composite dietary management with agni chikitsa in malnourished child-case study. Available from:  https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1526552586.pdf
  3. Mundugaru R, Ballal SR, Bhat S, Basavaiah R. Chronic toxicity studies of gandhaka rasayana – A herbo-mineral preparation used in Ayurvedic practice. J Ayurveda Integr Med. 2021 Oct-Dec;12(4):673-681. doi: 10.1016/j.jaim.2021.05.011. Epub 2021 Nov 1. PMID: 34736857; PMCID: PMC8642667. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8642667/
  4. Nair R. GANDHAKA RASAYAN — Benefits, Ingredients, Indications, Dosage, Usage, Preparation, Side Effects, Equivalent Medicines, Research Papers. Ayurveda Blogs, Services and Consultation [Internet]. 2022 Jul 6 [cited YEAR MONTH DAY]. Available from: https://ayurvedapc.blog/2022/07/06/gandhaka-rasayan-benefits-ingredients-indications-dosage-usage-preparation-side-effects-equivalent-medicines-research-papers/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Drumstick Tree (Moringa oleifera): Uses, Benefits and Side Effects By Dr. Rajeev Singh

Introduction

“As long as we are not living in harmony with nature, we cannot expect ourselves to heal.” Have you ever heard about the miracle tree? The drumstick tree or Moringa, is called the miracle tree as every part of it benefits humans and animals. Due to this reason, In Sanskrit, the drumstick tree is called Shobhanjana, meaning auspicious. Other names for the drumstick tree include the horseradish tree (English), Sainjna or Saguna (Hindi) and Akshiva or Haritashaaka (Ayurveda). The scientific name of drumstick tree is Moringa oleifera and it is a member of the Moringaceae family. It is a fast-growing evergreen tree cultivated worldwide from India to Africa and numerous other arid and other tropical countries. The leaves, flowers, seeds and roots of the drumstick trees are edible and are used to prepare a variety of delicious recipes. This “tree of life” has various benefits; let us know more about the uses and benefits of drumstick tree leaves1

Friendly Reminder: The information shared here is for educational purposes only and the reader should consult a registered medical practitioner before implementing any changes to their health routine.

Nutritional Value of Drumstick Tree

The leaves of the drumstick tree are packed with the goodness of carbohydrates, proteins, fats, carotenoids, vitamins A and E and minerals like potassium, calcium, iron, magnesium, etc. The phytochemicals in drumstick tree include flavonoids, phenolic compounds, glucosinolates and carotenoids. The nutritional value of the drumstick plant per 100 grams is given below: 

Based on my observations, I have found that different parts of the drumstick tree, including the leaves, pods, and roots, may possess pain-reducing properties. I recommend considering the use of drumstick as a natural remedy for pain relief7.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Drumstick Tree

Drumstick tree shows numerous scientifically proven properties; some of which are mentioned below1:  

Be careful when consuming Moringa leaves! They contain a high concentration of saponins, which can interfere with the absorption of important minerals like zinc and magnesium. It is important to be mindful of this potential risk and monitor your Moringa leaves intake8.

Dr. Smita Barode, B.A.M.S, M.S.

Potential Uses of Drumstick Tree for Overall Health

Some of the potential benefits of the Drumstick tree are described below: 

1. Potential Uses of Drumstick Tree in Colorectal Cancer

cancer

Cancers of the colon and rectum are the third most lethal cancers affecting both males and females equally. Asmari et al. conducted a review in 2015 stating that Drumstick tree halts the abnormal multiplication of colorectal cells and inhibits the formation and progression of cancer cells2. This effect is attributed due to the presence of eugenol, a polyphenol present in drumstick leaves. This indicates that the consumption of drumsticks may help manage colorectal cancers. Also, the presence of carotenoids and flavonoids may help in exerting a protective effect against cancers. However, to claim these results in humans, we need more studies. Additionally, it is advised to consult a physician for the proper management of colorectal cancer and not consider usage of drumstick trees as a remedy for cancers. 

2. Potential Uses of Drumstick Tree in Hypertension

blood pressure

High blood pressure or hypertension is a condition in which blood flows through the arteries at very high pressure. Direk et al. conducted an animal study3 in 2019 stating drumstick consumption helps in relaxing the arteries and thus helps reduce blood pressure. This states that drumsticks may have the potential to manage hypertension. However, we need more human trials to claim these effects with greater reliability. It is better to take a professional opinion if you suffer from high blood pressure instead of self-medicating. 

3. Potential Uses of Drumstick Tree in Colitis

stomach

Colitis is a condition characterised by inflammation and ulceration in the digestive tract. A review4 by Mohsen et al. done in 2014 states that drumsticks may have the potential to manage colitis by reducing inflammation and ulcers. This effect is attributed to the presence of polyphenols which exert anti-inflammatory and antioxidant properties. Thus, it may be concluded that drumsticks may have the potential to manage colitis. However, we need more human studies to claim these results with greater reliability. Additionally, it is always advised to consult a physician for the proper management of colitis and not rely on self-medication with the drumstick tree. 

4. Potential Uses of Drumstick Tree as an Antibacterial Agent

urinary tract infections

Medicinal plants like the drumstick tree are coming into the limelight as antibacterial agents. Abalaka et al. conducted a study5 in 2012 to test the efficacy of the drumstick trees on different bacteria like E.coli, H.pylori, S.typhi, K.pneumonia, etc. A plant-based chemical called glucosinolate present in the leaves of this tree inhibits the growth of these bacteria; thus drumstick leaves may have the potential to manage bacterial infections caused by the above-mentioned bacteria and help in managing infections like urinary tract infections, typhoid, pneumonia, etc. However, we need more studies to confirm these results in humans. It is recommended to avoid self-medication and consult your physician for the proper management of any bacterial infection. 

5. Potential Uses of Drumstick Tree for Diabetes

diabetes

Diabetes (Type I & II) is a metabolic disorder characterised by an increase in blood glucose due to decreased production or resistance of a hormone called insulin which regulates blood glucose. A review1 conducted by Piyush et al. in 2022 stated that the drumstick tree might have the potential to decrease blood glucose levels. This effect is attributed to polyphenols that inhibit enzymes that break down carbohydrates into simpler sugars and increase blood glucose. Additionally, the antioxidant effect plays an important role in reducing the increased blood glucose. Therefore, the leaves of drumstick tree may have the potential to manage diabetes. However, it is advised not to generalise these results in the management of diabetes. To claim these results and apply them in humans, we need more studies. In addition, you should consult your physician for the proper management of diabetes and not rely on self-medication. 

6. Other Potential Uses of Drumstick Tree

asthma

Though there are studies that show the benefits of Drumstick tree in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of drumstick tree on human health.  

I highly recommend incorporating drumstick tree extracts into your diet, as it might be an exceptional source of vitamin A. This essential nutrient has the potential to safeguard your eye health and stave off deficiencies. Including drumsticks in your meals, especially for your children, is a great step towards maintaining optimal vision and promoting eye health7.

Dr. Rajeev Singh, BAMS

How to Use Drumstick Tree?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Also Read: Pancharishta: Uses, Benefits and Side Effects By Dr. Rajeev Singh

Side Effects of Drumstick Tree

A review1 by George et al. in 2016 stated that drumstick contains high metallic content which can be toxic to humans. Therefore, excessive consumption of drumsticks should be avoided. 

However, if you experience any adverse reactions to the drumstick tree, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Also Read: Banana Leaf: Uses, Benefits, Side Effects By Dr. Smita Barode

Precautions to Take with Drumstick Tree

Consuming Drumstick tree is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions1:  

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Drumstick tree with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking. 

Frequently Asked Questions (FAQs)

What is Drumstick tree scientific name? 

The scientific name of the drumstick tree is Moringa oleifera and it is a member of the Moringaceae family1

Which tree is called the miracle tree? 

The drumstick tree is called the miracle tree1

What is Drumstick tree in Hindi?  

In Hindi, the drumstick tree is called as Sainjna or Saguna. 

Does the Drumstick tree benefit weight loss? 

Yes, intake of the leaves of the Drumstick tree may help in weight loss.

Does the usage of Drumstick tree leaves help in managing jaundice? 

There is no study stating benefits of drumstick leaves to manage jaundice.

References

  1. Al-Asmari, Abdulrahman Khazim et al. “Moringa oleifera as an Anti-Cancer Agent against Breast and Colorectal Cancer Cell Lines.” PloS one vol. 10,8 e0135814. 19 Aug. 2015, doi:10.1371/journal.pone.0135814. available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545797/ 
  2. Aekthammarat, Direk et al. “Moringa oleifera leaf extract lowers high blood pressure by alleviating vascular dysfunction and decreasing oxidative stress in L-NAME hypertensive rats.” Phytomedicine : international journal of phytotherapy and phytopharmacology vol. 54 (2019): 9-16. doi:10.1016/j.phymed.2018.10.023. Available at: https://pubmed.ncbi.nlm.nih.gov/30668387/ 
  3. Mohsen et al. “Anti-inflammatory effect of Moringa oleifera Lam. seeds on acetic acid-induced acute colitis in rats.” Avicenna journal of phytomedicinevol. 4,2 (2014): 127-36. Available at: https://pubmed.ncbi.nlm.nih.gov/25050310/ 
  4. Abalaka M.E., Daniyan S.Y., Oyeleke S.B., Adeyemo S.O. The Antibacterial Evaluation of Moringa oleifera Leaf Extracts on Selected Bacterial Pathogens. J. Microbiol. Res. 2012;2:1–4. doi: 10.5923/j.microbiology.20120202.01. available at: http://article.sapub.org/10.5923.j.microbiology.20120202.01.html 
  5. Suresh S., Chhipa A.S., Gupta M., Lalotra S., Sisodia S.S., Baksi R., Nivsarkar M. Phytochemical Analysis and Pharmacological Evaluation of Methanolic Leaf Extract of Moringa oleifera Lam. in Ovalbumin Induced Allergic Asthma. S. Afr. J. Bot. 2020;130:484–493. doi: 10.1016/j.sajb.2020.01.046. available at: https://www.sciencedirect.com/science/article/pii/S0254629919313572?via%3Dihub 
  6. Mabrouki, Lamia et al. “Cardiac Ameliorative Effect of Moringa oleifera Leaf Extract in High-Fat Diet-Induced Obesity in Rat Model.” BioMed research international vol. 2020 6583603. 27 Feb. 2020, doi:10.1155/2020/6583603. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064870/?report=reader 
  7. Islam Z, Islam SMR, Hossen F, Mahtab-ul-Islam K, Hasan MR, Karim R. Moringa oleifera is a Prominent Source of Nutrients with Potential Health Benefits. Int J Food Sci. 2021;2021:6627265. doi:10.1155/2021/6627265. Available from: https://onlinelibrary.wiley.com/doi/10.1155/2021/6627265
  8. García Milla P, Peñalver R, Nieto G. Health Benefits of Uses and Applications of Moringa oleifera in Bakery Products. Plants. 2021;10(2):318. doi:10.3390/plants10020318. Available from: https://www.mdpi.com/2223-7747/10/2/318

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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