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Trayodashang Guggulu: Uses, Benefits and Side Effects By Dr. Smita Barode 

Introduction

Trayodashang guggulu is one of the primary Ayurvedic polyherbal formulations. It consists of Babula (the stem bark of Acacia nilotica), Hapusa (the fruits of Juniperus communis), Shatavari (the roots of Aspargus recemosus), Ashwagandha (the roots of Withania somnifera), Sunthi (the rhizome of Zingiber officinale), Satavha (the fruits of Anethum sowa), Vradadaru (the roots of Argyeria nervosa), Sati (the rhizome of Hidichium spicatum), Shuddha guggulu (exudates of Commiphera mukul), Rasana (the roots and leaves of Pluchea lanceolata), Guduchi (the stem of Tinospora cordifolia), Gokshuara (the fruits Tribulus terrestris), Yavani (Trachyspermum ammi fruits) and Goghrat (ghee). The ayurveda formulation trayodashang guggulu is mentioned in the Ayurveda classic Bhaishaja Ratnavali and the Ayurveda Formulary of India. Trayodashang guggulu may be used for various ailments. Let us look at some of the health benefits of trayodashang guggulu1

Nutritional Value of Trayodashang Guggulu

The composition of trayodashang guggulu is as follows: 

Properties of Trayodashang Guggulu

Several studies have shown that Trayodashang guggulu may have the following properties: 

Potential Uses of Trayodashang Guggulu for Overall Health

Some of the potential uses of trayodashang guggulu are: 

1. Potential Uses of Trayodashang Guggulu for Spondylosis

spondylosis

The worst diet habits with the western lifestyle and continuous work in front of laptops are the major reasons for spondylosis. Trayodashang guggulu may be used against spondylosis. A study2 by Sawant et al. in 2017 showed that Trayodashang guggulu might be beneficial for cervical spondylosis. Constituents like Shatavari, Ashwagandha and Guduchi are rejuvenators and may give stability to the muscles (dhatus). Whereas babbul acts on bones (asthidhatwagni) and may provide firmness. However, further studies are required to check if trayodashang guggulu may help in the case of cervical spondylosis. Therefore, you must consult your doctor if you experience any symptoms of cervical spondylosis. Do not self-medicate. 

2. Potential Use of Trayodashang Guggulu as an Antioxidant

trayodashang guggulu as an antioxidant

The phenols, alkaloids, flavonoids and other phenolic compounds present in trayodashang guggulu may show antioxidant activity. This was demonstrated by a study1 by Dadoriya et al. in 2018. It may deactivate the free radicals (harmful molecules present in the body) and protect them from various damages.  Further studies are required to check the antioxidant activity of trayodashang guggulu. 

From my experience, Trayodashang Guggulu may aid in gout. Studies1 suggest that Trayodashang Guggulu shows antioxidant and anti-inflammatory effects that make it a potential remedy in cases of inflammatory disease such as gout.

Dr. Siddharth Gupta, BAMS, MD (Ayu)

3. Potential Use of Trayodashang Guggulu for Inflammation

reduces inflammation

Trayodashang guggulu may be beneficial for several inflammatory conditions like the stiffness of the knee, bone marrow disorder, lockjaw, inflammation of ligaments, neurological and musculoskeletal diseases, pain in the arm and cardiac failure and bone fracture due to the presence of bioactive compounds like flavonoids and phenols. A study1 by Dadoriya et al. in 2018 showed that trayodashang guggulu might inhibit proteinase and lipoxygenase (enzymes that promote inflammation). However, further studies are required to check if trayodahsang guggulu may reduce inflammation. Therefore, you must consult your doctor if you suspect inflammation.  

4. Potential Use of Trayodashang Guggulu for Arthritis

Arthritis

Arthritis is a disease associated with inflammatory pain. Bioactive compounds like flavonoids and phenols present in trayodashang guggulu may be responsible for reducing inflammatory pain. A study3 by Gupta et al. in 2022 showed that trayodashang guggulu might inhibit inflammatory mediators like COX-2 and reduce inflammatory pain, which may be beneficial for arthritis. Inflammatory mediators are molecules in the body that cause inflammation. However. Further studies are required to check if trayodashang guggulu may be helpful in the case of arthritis. Therefore, you must consult your doctor if you experience any symptoms of arthritis.  

5. Potential Use of Trayodashang Guggulu for Sciatica

lower back

Sciatica refers to the pain radiating down one or both legs from the lower back along the sciatic nerve. According to the studies5 by Moharana et al. in 2018, trayodashang guggulu may be beneficial in the case of sciatica. Effects of trayodashang guggulu are particularly noticeable in vata dosha, the primary cause of joint and bone-related disorders3,7. However, further studies are required to check if trayodashang guggulu may be beneficial for sciatica. You must immediately consult your doctor if you suspect any symptoms of sciatica. 

6. Potential Use of Trayodashang Guggulu for Tennis Elbow

tennis elbow

The condition that causes pain in the forearm is known as the tennis elbow. Pain, tenderness, restricted movement, stiffness and diminished grip strength are the primary clinical signs of tennis elbow. The study6 by Rajurkar et al. in 2022 showed that the trayodashang guggulu tablet might reduce pain and functional disability related to the tennis elbow. However, further studies are required to check if trayodashang guggulu may be beneficial in the case of tennis elbow. Therefore, you must consult your doctor if you experience any symptoms of tennis elbow. 

7. Potential Use of Trayodashang Guggulu for Osteoporosis

bone health

Trayodashanga Guggulu may directly affect the Asthigata Vata (bone and soft tissue pain) and brings the vitiated Vata Dosha back into balance. An imbalance in vata dosha causes conditions related to joints and bones. The Ayurvedic mind-body element associated with air and space is called vata dosha. It governs all movement and processes in your mind and body, including blood flow, elimination, breathing and thought action. A Vata imbalance may lead to bone thinning, according to Ayurveda. Therefore, trayodashang guggulu may be beneficial in case of osteoporosis. This was shown by a study7 conducted by Sannakki et al. in 2020. However; further studies are required to check if trayodashang guggulu may be beneficial for osteoporosis. Therefore, you must consult your doctor if you experience any symptoms of osteoporosis. 

8. Potential Use of Trayodashang Guggulu for Enhancing the Immune System

Immunity

According to the study4 by Prasad et al. in 2016, trayodashang guggulu may help improve the immune system. It may have immune-modulating properties, which may stimulate the immune system. However, further studies are required to check if trayodashang guggulu may affect the immune system. 

Though studies show the benefits of trayodashang guggulu in various situations, these are insufficient and further studies are needed to establish the true extent of trayodashang guggulu on human health. 

How to Use Trayodashang Guggulu?

Trayodashang guggulu is a polyherbal ayurveda preparation that is available as a tablet. It can be given with gruel (thin porridge), warm water and milk of meat soup5

You must consult a doctor before taking large quantities of trayodashang guggulu or herbal supplements. Do not discontinue an ongoing modern medical treatment with an ayurvedic/herbal preparation without consulting a qualified doctor. 

Side Effects of Trayodashang Guggulu

A high dose of trayodashang guggulu may have the following side effects: 

You must consult your doctor if you experience any side effects after consuming trayodashang guggulu. 

Also Read: Nagkesar (Mesua Ferrea): Benefits, Uses, Side Effects & More!

Precautions to Take with Trayodashang Guggulu

As with any other general medicine, general precautions should be taken while having trayodashang guggulu. You must consult your doctor before having trayodashang guggulu. Pregnant women and lactating mothers should take special care. Precaution should be taken before giving trayodashang guggulu to the elderly or children. In such cases, you must have trayodashang guggulu only if your doctor prescribes it. 

Also Read: Licorice (Mulethi): Uses, Benefits, Side Effects, and More!

Interactions with Other Drugs

There is not enough evidence on the interaction of trayodashang guggulu with other drugs. Further studies on the interaction of trayodashang guggulu are required. Therefore, you must consult your doctor if you are on any other medication before consuming trayodashang guggulu. 

Also Read: Raisins (Kishmish): Uses, Benefits, Side Effects By Dr. Smita Barode

Frequently Asked Questions (FAQs)

What are the components of trayodashang guggulu?

Trayodashang guggulu is an essential Ayurvedic polyherbal formulation. It consists of Babula, Hapusa, Shatavari, Ashwagandha, Sunthi, Satavha, Vradadaru, Sati, Shuddha guggulu, Rasana, Guduchi, Gokshuara, Yavani and Goghrat (ghee)1

What are the health benefits of trayodashang guggulu? 

Trayodashang guggulu may be used to reduce pain and inflammation. It may act against the conditions like tennis elbow, arthritis, osteoporosis, sciatica and cervical spondylosis. It may have antioxidant properties and may enhance the immune system. However, further studies are required to check whether trayodashang guggulu may benefit the mentioned conditions. Therefore, you must consult your doctor if you experience symptoms of the mentioned conditions1,6

How can you consume trayodashang guggulu? 

Trayodashang guggulu is a polyherbal ayurveda preparation that is available as a tablet. It can be given with gruel (thin porridge), warm water and milk of meat soup4

What are the side effects of trayodashang guggulu? 

Trayodashang guggulu may cause stomach upset, belching, indigestion and loss of appetite. You must consult your doctor if you experience any side effects8

How is trayodashang guggulu beneficial for arthritis? 

Bioactive compounds like flavonoids and phenols present in trayodashang guggulu may be responsible for reducing inflammatory pain. They might inhibit inflammatory mediators (molecules in the body that cause inflammation) and reduce inflammatory pain, which may be beneficial for arthritis3. However, you must consult your doctor if you experience any symptoms of arthritis. 

References

  1. Dadoriya P, Dey YN, Sharma D, Yadav M, Wanjari MM, Gaidhani SN, Subhose V. In-vitro anti-inflammatory and antioxidant activities of an Ayurvedic formulation–Trayodashang guggulu. Journal of Herbal Medicine. 2020 Oct 1;23:100366. Available from: https://www.sciencedirect.com/science/article/pii/S2210803320300385 
  2. Rathod HS, Sawant RS. Evaluation of efficacy of Trayodashang guggulu in management of Cervical spondylosis (Manyagata vata). J Biol Sci Opin. 2013;1(2):65-9. Available from: https://www.researchgate.net/publication/315330757_EVALUATION_OF_EFFICACY_OF_TRAYODASHANG_GUGGULU_IN_MANAGEMENT_OF_CERVICAL_SPONDYLOSIS_MANYAGATA_VATA 
  3. Gupta S, Dey YN, Kannojia P, Halder AK, Sharma D, Wanjari MM, Chougule S, Pawar S, Kaushik A, Gaidhani SN, Gurav S. Analgesic and Anti-inflammatory Activities of Trayodashang Guggulu, an Ayurvedic Formulation. Phytomedicine Plus. 2022 Aug 1;2(3):100281. Available from: https://www.sciencedirect.com/science/article/pii/S2667031322000641
  4. Prasad R. Guggulu preparations: Gold standards in the management of Joint disorders. British Journal of Medical and Health Research. 2016 Jan. Available from: https://www.researchgate.net/publication/335716125_Guggulu_preparations_Gold_standards_in_the_management_of_Joint_disorders 
  5. Moharana PK, Patel A. Synergistic effect of Trayodashang Guggulu and yoga basti in the management of low back pain with special reference to Gridhrasi. Int J Health Sci Res. 2018;8:167-73. Available from: https://www.ijhsr.org/IJHSR_Vol.8_Issue.12_Dec2018/27.pdf 
  6. Rajurkar H, Misar S, Dandekar P, Kane S, Dawande P, Damahe LB. Assessment of comparative Efficacy of Nirgundipatra Upanaha and Trayodashang Guggulu with Diclofenac sodium Gel and Ibuprofen in the Management of Snayugata Vata Affecting Koorpara Sandhi (Tennis Elbow). Australasian Medical Journal. 2022 Feb 1;15(2). Available from: https://amj.net.au/index.php/AMJ/article/viewFile/3866/2018 
  7. Sannakki SY, Kalyani SS, MH M. Paryeshana International Journal of Ayurvedic Research. Available from: http://pijar.org/articles/Arch_Vol5_Issue5/13.Dr.Sumitkumar%20Y%20Sannakki.pdf 
  8. Sahiti M, Gurupadayya BM, Dinesh TK. Evaluation of in vitro anti-inflammatory activity of Trayodashang Guggulu: An ayurvedic formulation in comparison with allopathic drug. Int J Res Ayurveda Pharm. 2019;10(3):92-6. Available from: https://www.researchgate.net/publication/335188499_EVALUATION_OF_IN_VITRO_ANTI_INFLAMMATORY_ACTIVITY_OF_TRAYODASHANG_GUGGULU_-_AN_AYURVEDIC_FORMULATION_IN_COMPARISION_WITH_ALLOPATHIC_DRUGS 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any change

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Jackfruit Seed: Uses, Benefits and Side Effects By Dr. Rajeev Singh 

Introduction

Jackfruit is the largest tree fruit that gained popularity due to its sweet, fleshy and energy-rich pulp. The exterior of jackfruit is hard green or yellow initially and turns to yellowish brown after ripening. The inner edible flesh of the jackfruit consists of nutritious pulp coated around the seed, formed by the fusion of flowers. Jackfruit is a non-seasonal fruit that grows on evergreen trees in tropical areas. The biological name of the jackfruit tree is Artocarpus heterophyllus Lam, belonging to the family Moraceae. It is cultivated in Bangladesh, Sri Lanka, Malaysia and various parts of Southeast Asia, Africa and America. Jackfruit grows abundantly in India and is native to the Western Ghats of India1,2

Apart from the flesh, jackfruit seeds are also edible and are used in cooked dishes. The jackfruit seeds with a thin brown seed coat, known as spermoderm, are enclosed in a white layer. The brown spermoderm consists of white cotyledon rich in protein and starch. Jackfruit seed has a lot of potential benefits, especially in the cosmetics, paper, pharmaceutical and bio-nanotechnology industries2.

Did you know?

Nutritional Value of Jackfruit Seed

The nutrient value of jackfruit seed is as under: 

Properties of Jackfruit Seed

Potential Uses of Jackfruit Seed for Overall Health

The potential health benefits of jackfruit seed are: 

1. Potential Uses of Jackfruit Seed for Strengthening Bones 

Magnesium is a mineral crucial for body functioning and keeps our bones strong by absorbing calcium in bones. Calcium makes our bones strong and rigid and allows normal body movement. Swami et al., 2012 presented an overview of the functional and medicinal value of Jackfruit. They mentioned that jackfruit seeds are rich in magnesium, which may help in the absorption of calcium in the bones. Magnesium, along with calcium, strengthens bones and relieves disorders related to bones, e.g. osteoporosis (weak and brittle bones). Thus, it is suggested that jackfruit seeds may have potential benefits in strengthening the bones. Further studies should be conducted to validate the efficacy of jackfruit seeds2.  

2. Potential Uses of Jackfruit Seed as an Antioxidant 

Antioxidants are agents that reduce the effects of free radicals responsible for chronic health problems. Ranasinghe et al. in 2019 mentioned that jackfruit seeds possess a good amount of ascorbic acid and gallic acid which may protect the body from the negative effects of excess free radical production thus promoting antioxidant activity. Therefore, it can be concluded that jackfruit seeds may help in contributing to the antioxidant activity. More data is required to establish the true extent of its benefit on human health1.

3. Potential Uses of Jackfruit Seed as an Antibacterial Agent 

Mahanta et al., 2015 and Ranasinghe et al., 2019 mention that the jackfruit seeds extract has shown efficacy against S.aureus, E. coli and B. megaterium revealing that jackfruit seed may have some antimicrobial effects. It may be used to formulate pharmaceutical agents for infectious diseases. Jackfruit seed powder may also help against food contamination. Thus, the seeds of jackfruit may have the potential as an antibacterial agent. Further research should be conducted to validate the efficacy of jackfruit seeds1,3.  

4. Potential Uses of Jackfruit Seed as an Antidiabetic Agent 

Dwitiyanti et al., 2019 conducted a study on pregnant female rats. The jackfruit seed extract was administered to diabetic pregnant female rats. The blood glucose levels of pregnant female rats decreased after the administration of jackfruit seed extracts. Therefore, it is suggested that the jackfruit seed extract possesses activities that may have the potential of decreasing blood sugar levels. Further clinical research is required to investigate the true benefit of jackfruit seed in human health5

5. Other Potential Uses

Though there are studies that show the benefits of jackfruit seed in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of jackfruit seed on human health.  

Due to their high fibre content, I’ve experienced that jackfruit seeds may help reduce the risk of heart disease, avoid constipation, and may aid in weight reduction. They are also a good source of B-complex vitamins. Additionally, resistant starch, which may regulate blood sugar and may maintain intestinal health, is included in jackfruit seeds6.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

How to Use Jackfruit Seed?

You must consult a qualified doctor before taking any jackfruit seed supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Additionally, the researchers have found that the seeds have an abundance of highly soluble protein that may aid in the management of anxiety and stress6.

Dr. Rajeev Singh, BAMS

Side Effects of Jackfruit Seed

The most common side effects related to jackfruit seed are: 

Also Read: Jackfruit (Kathal): Uses, Benefits, Side Effects and More!

Precautions to Take with Jackfruit Seed

Patients suffering from digestive disorders must consult their physician before consuming jackfruit seeds. Though, there is not much data available on the consumption of jackfruit seeds during pregnancy and breastfeeding. Thus, lactating and pregnant females should ask their gynaecologist before consuming jackfruit seeds. The elderly and children should also consume jackfruit seeds in moderation if necessary and consult a physician if suffering from any health-related disorders. 

In my experience, the seeds have a very poor capacity to absorb water and fat. Hence, it may aid in maintaining a healthy weight6.

Dr. Smita Barode, B.A.M.S, M.S.

Also Read: Lotus Seed: Uses, Benefits, Side Effects and More By Dr. Smita Barode

Interactions with Other Drugs

No interactions are reported in the literature reviewed. If you are on medication, consult an experienced and qualified doctor before taking any jackfruit seed supplements. This can possibly help in avoiding interaction with other medicines. 

Also Read: Hemp Seed: Uses, Benefits and Side Effects by Dr. Smita Barode

Frequently Asked Questions (FAQs)

Is jackfruit seed edible?  

The seed of jackfruit contains a high amount of protein and other vitamins and minerals, which adds to its nutritional value. Thus, jackfruit seed is edible and is used as a nutritious source of food.  

How are jackfruit seeds used? 

Jackfruit seeds are used after boiling, roasting or cooking. The seeds are boiled in sugar water to serve as a dessert. It may also be used as an ingredient in vegetables and curries in Asian dishes.  

What are the benefits of jackfruit seeds? 

The jackfruit seeds may serve a potential in human health and may benefit as an antimicrobial, antidiabetic and antioxidant. It may also provide benefits in strengthening the bones. It may also be used as a substitute to flour with an increase in protein and fibre content. 

Who should avoid eating jackfruit seeds? 

The patients suffering from digestive disorders must avoid consuming jackfruit seeds. Elderly, children and pregnant and lactating females should consult the doctor before taking jackfruit seeds in any form. 

How is jackfruit seed flour used? 

The flour of jackfruit seed may be used in various bakeries and biscuit factories to make cookies. It might also be used as binding and thickening agent in various food industries. 

References

  1. Ranasinghe RA, Maduwanthi SD, Marapana RA. Nutritional and health benefits of jackfruit (Artocarpus heterophyllus Lam.): a review. International journal of food science. 2019 Jan 6;2019. Available form: https://www.hindawi.com/journals/ijfs/2019/4327183/  
  1. Swami SB, Thakor NJ, Haldankar PM, Kalse SB. Jackfruit and its many functional components as related to human health: a review. Comprehensive Reviews in Food Science and Food Safety. 2012 Nov;11(6):565-76. Available form : https://ift.onlinelibrary.wiley.com/doi/abs/10.1111/j.1541-4337.2012.00210.x  
  1. Mahanta CL, Kalita D. Processing and utilization of jackfruit seeds. InProcessing and impact on active components in food 2015 Jan 1 (pp. 395-400). Academic Press. Available form: https://www.sciencedirect.com/science/article/pii/B9780124046993000470  
  1. Waghmare R, Memon N, Gat Y, Gandhi S, Kumar V, Panghal A. Jackfruit seed: an accompaniment to functional foods. Brazilian Journal of Food Technology. 2019 Jun 13;22. Available form: https://www.scielo.br/j/bjft/a/5yY7zY6RXVSQQFgnPyKtTqj/abstract/?lang=en  
  1. Dwitiyanti D, Rachmania RA, Efendi K, Septiani R, Jihadudin P. In Vivo Activities and In Silico Study of Jackfruit Seeds (Artocarpus heterophyllus L.am.) on the Reduction of Blood Sugar Levels of Gestational Diabetes Rate Induced by Streptozotocin. Open Access Macedonian Journal of Medical Sciences. 2019 Nov 30;7(22):3819. Available form: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048328/  
  2. Waghmare R, Memon N, Gat Y, Gandhi S, Kumar V, Panghal A. Jackfruit seed: an accompaniment to functional foods. Brazilian Journal of Food Technology [Internet]. 2019 [cited 2025 Oct 9];22:e2018207. Available from: https://www.scielo.br/j/bjft/a/5yY7zY6RXVSQQFgnPyKtTqj/?lang=en#:~:text=The%20seeds%20are%20rich%20in,and%20keeps%20the%20gut%20healthy.

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Phalsa fruit (Grewia asiatica): Uses, Benefits, and Side Effects By Dr. Smita Barode 

Introduction

“With the changing times, not only the country’s policymakers but the whole world is realising the importance of Ayurveda. Who would’ve thought that people in the upcoming generations would prefer a bottle of gooseberry or bottle gourd juices over carbonated drinks?” Despite this realization of the health benefits of plants and fruits, there are fruits like Phalsa which, although are high in nutrients but low in popularity. Phalsa is a plant that originates in Southeast Asian countries like India, Nepal, Sri Lanka and Bangladesh and is mainly grown for its fruit. The scientific name of the Phalsa fruit is Grewia asiatica, also known as the Indian Sherbet berry. It is a seasonal plant and the fruits are generally obtained in the summer. Phalsa fruit resembles grapes in its shape and size. They are purple in colour with a sour-sweet taste. The fruit is a powerhouse of vitamins and minerals and offers many health benefits; let us know more about those benefits1

Nutritional Value of Phalsa Fruit

Phalsa fruit is rich in carbohydrates, fibres, proteins, vitamins A, B3 and C and minerals like potassium, calcium, iron and phosphorus. The phytochemicals present in Phalsa fruit include anthocyanins, tannins, phenols and flavonoids. The nutritional chart of this fruit is given below.  

Properties of Phalsa Fruit

Phalsa fruit shows numerous scientifically proven properties; some of which are mentioned below1

I’ve discovered that Phalsa fruits have a cooling effect on the body. Phalsa fruit is rich in phenols. This property makes it a potential natural remedy for excessive body heat9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Phalsa Fruit for Overall Health

Some of the potential benefits of Phalsa fruit are described below. 

1. Potential Use of Phalsa Fruit in Diabetes

diabetes

Diabetes (Type I & II) is characterised by an increase in blood glucose due to a reduction or resistance to insulin (a hormone that regulates blood glucose). Literature shows that fruits rich in polyphenols may positively impact diabetes. Parveen et al. conducted a study2 on diabetic rabbits in 2013 to assess the effect of Phalsa fruit on blood glucose. This study showed a reduction in rabbits’ blood glucose after administering Phalsa fruit. Additionally, this fruit has a low glycemic index and the presence of polyphenols may help reduce blood glucose levels. This indicates that Phalsa fruit may help manage diabetes. However, to claim these results in humans, we need more studies. It is further advised not to self-medicate and consult your physician for proper management of diabetes3

2. Potential Uses of Phalsa Fruit in Dyslipidemia

cholesterol

Dyslipidemia is characterised by an increase in total cholesterol and triglycerides. Studies have shown that Phalsa fruit may potentially control the altered parameters in dyslipidemia. An animal study4 conducted by Parveen et al. in 2013 showed a positive relationship between the consumption of this fruit and lipid levels. Rabbits administered Phalsa fruit extract (200mg/kg) showed reduced total cholesterol and triglycerides. This may indicate that this fruit’s consumption may help manage dyslipidemia. However, more studies on humans are needed to support these claims. Additionally, it is advised not to rely on Phalsa fruit as a remedy for managing dyslipidemia and kindly consult your physician for the proper management of dyslipidemia. 

3. Potential Uses of Phalsa Fruit in Breast Cancer

breast cancer

Breast cancer is one of the most common cancers affecting women worldwide; different ayurvedic treatments are being tested for their effectiveness towards breast cancer. A review2 by Muhammed et al. in 2013 states that Phalsa fruit contains smart molecules called anthocyanins which help reduce the multiplication of abnormal cells and the risk of cancers. Thus, it may be concluded that Phalsa fruit may reduce breast cancer risk. However, we need more human studies to claim these results accurately. Also, it is advised not to consider Phalsa fruit as an alternative to modern medicine; you should always consult your doctor for proper management of breast cancer. 

4. Potential Uses of Phalsa Fruit as an Antibacterial Agent

phalsa fruit

Traditionally, herbs, spices, leaves and fruits obtained from plants were used for managing bacterial infections. Muhammed et al. conducted a review2 in 2013 to test the efficacy of Phalsa fruit on different bacteria. The presence of polyphenols in Phalsa fruit inhibited the growth of S.typhi bacteria; thus, it may have the potential to manage bacterial infections like Typhoid caused by S.typhi bacteria. However, we need more studies to confirm these results in humans. Additionally, you should not consider Phalsa fruit as a remedy for managing Typhoid; it is always advised to consult a physician for proper management of Typhoid. 

5. Potential Uses of Phalsa Fruit in Depression

stress

Depression is a mood disorder that results in sadness and loss of interest and may affect everyday activities. Previous studies have shown that healthy nutrition may help in managing various ailments. A study4 conducted by Imran et al. in 2021 stated that Phalsa fruit, due to the presence of antioxidants like phenols, anthocyanins, flavonoids, etc., may help in managing depression. Additionally, this fruit can potentially reduce anxiety (anxiolytic effect). Therefore, Phalsa fruit may have the potential to manage depression. To claim these results for humans, we need more studies. It is further advised not to consider Phalsa fruit as an alternative to modern medicine; kindly consider your doctor for proper management of depression5

6. Other Potential Uses of Phalsa Fruit

digestion problems

Though there are studies that show the benefits of Phalsa fruit in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of Phalsa fruit on human health.  

Let me give you a tip! Phalsa fruit might take care of your skin. Phalsa fruit is rich in antioxidants and numerous vitamins and minerals, which makes Phalsa a potential contributor to achieving flawless skin10.

Dr. Rajeev Singh, BAMS

How to Use Phalsa Fruit?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Phalsa Fruit

Phalsa fruit is considered safe when eaten in minimal amounts. A few side effects related to the consumption of Phalsa fruit include: 

However, if you experience any adverse reactions to Phalsa fruit, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Also Read: Mango (Aam): Uses, Benefits, Side Effects by Dr. Smita Barode

Precautions to Take with Phalsa Fruit

Consuming Phalsa fruit is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions1

Also Read: Hadjod (Cissus Quadrangularis): Uses, Benefits, Side Effects & More!

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Phalsa fruit with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking. 

Also Read: Shallaki (Boswellia serrata): Uses, Benefits, Side Effects & More!

Frequently Asked Questions (FAQs)

What does Phalsa fruit look like? 

Phalsa fruit resembles grapes in its shape and size. They are purple in colour and sour to sweet in taste1.

What is the scientific name of Phalsa fruit? 

Phalsa fruit is called Grewia asiatica1. 

What is Phalsa fruit in Hindi? 

In Hindi, Phalsa fruit is called Sherbet berry.

Does the Phalsa fruit benefits weight loss? 

No, there are no proven results on the efficacy of the Phalsa fruit for reducing weight.

Is it okay to eat Phalsa fruit during pregnancy? 

The safety of Phalsa fruit consumption in pregnancy is not well-established; it is therefore advised to consult your doctor if you plan to add Phalsa fruit to your diet. 

References

  1. Mehmood, Arshad et al. “Nutraceutical perspectives and value addition of phalsa (Grewia asiatica L.): A review.” Journal of food biochemistry vol. 44,7 (2020): e13228. doi:10.1111/jfbc.13228. available at: https://pubmed.ncbi.nlm.nih.gov/32320069/ 
  2. Muhammad et al. “Grewia asiatica L., a food plant with multiple uses.” Molecules (Basel, Switzerland) vol. 18,3 2663-82. 28 Feb. 2013, doi:10.3390/molecules18032663. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270019/ 
  3. Khattab, Hala A H et al. “Antihyperglycemic Potential of Grewia asiatica Fruit Extract against Streptozotocin-Induced Hyperglycemia in Rats: Anti-Inflammatory and Antioxidant Mechanisms.” Oxidative medicine and cellular longevity vol. 2015 (2015): 549743. doi:10.1155/2015/549743. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542021/ 
  4. Imran et al. “Grewia asiatica Berry Juice Diminishes Anxiety, Depression and Scopolamine-Induced Learning and Memory Impairment in Behavioral Experimental Animal Models.” Frontiers in nutrition vol. 7 587367. 15 Jan. 2021, doi:10.3389/fnut.2020.587367. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844311/ 
  5. Chand, Suma P. and Hasan Arif. “Depression.” StatPearls, StatPearls Publishing, 18 July 2022. Available at: https://pubmed.ncbi.nlm.nih.gov/28613597/ 
  6. Khan, Rao & Asghar, Waqas & Khalid, Nauman & Nazir, Wahab & Farooq, Muhammad & Ahmed, Iftikhar & Syed, Qamar Abbas. (2019). Phalsa (Grewia asiatica L) fruit berry a promising functional food ingredient: A comprehensive review. Journal of Berry Research. 9. 10.3233/JBR-180332. Available at: https://www.researchgate.net/publication/329936198_Phalsa_Grewia_asiatica_L_fruit_berry_a_promising_functional_food_ingredient_A_comprehensive_review 
  7. Chung, K T et al. “Tannins and human health: a review.” Critical reviews in food science and nutrition vol. 38,6 (1998): 421-64. doi:10.1080/10408699891274273. Available at: https://pubmed.ncbi.nlm.nih.gov/9759559/ 
  8. Skibola, C F and M T Smith. “Potential health impacts of excessive flavonoid intake.” Free radical biology & medicine vol. 29,3-4 (2000): 375-83. doi:10.1016/s0891-5849(00)00304-x. Available at: https://pubmed.ncbi.nlm.nih.gov/11035267/ 
  9. Sivakumar D, Sultanbawa Y, Netzel M, editors. Handbook of Phytonutrients in Indigenous Fruits and Vegetables. CABI; 2022. P. 390. Available from: https://books.google.co.in/books?hl=en&lr=&id=vFacEAAAQBAJ&oi=fnd&pg=PA390&dq=phalsa+fruit+medicinal+uses&ots=rVQOJWvYfP&sig=Vz0jO1LIB6RpAMcHA-VCfL6a-eY&redir_esc=y#v=onepage&q=phalsa%20fruit%20medicinal%20uses&f=false
  10. Hassan H, Amin M, Rajwana IA, Ullah S, Razzaq K, Faried HN, et al. Nutritional functions and antioxidative enzymes in juice extract from two different maturity stages of low temperature stored phalsa (Grewia subinaequalis D.C.) fruit. LWT – Food Science and Technology. 2022;153:112552. Available from: https://www.sciencedirect.com/science/article/pii/S0023643821017059

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Gandhak Rasayan: Uses, Benefits, Side Effects and More!

Introduction

Gandhak Rasayan is a herbal medicine, known as Moringa ovalifolia in various botanical sources.  The formulations made from Gandhaka are referred to as Gandhaka Kalpas, where Gandhak in English refers to sulfur and Kalpas refers to medicinal preparation. It is used as a rejuvenator in Ayurveda, which promotes positive health and immunity. The increase in immunity helps the human body to resist various diseases. This property of Gandhak Rasayan also makes it a prophylactic agent (an agent that prevents disease) along with a therapeutic agent.  

According to ancient scholars, it is known as “Balivas”, as the king of Bali uses this very attractive sulfur internally to gain more power. Also, if Gandhak is combined with mercury, it transforms into a substance capable of eliminating diseases, known as murcchita state. Thus, gandhak based preparation has widespread clinical use and therefore, holds an important place in ayurvedic pharmaceutics1,3.

Nutritional Value of Gandhak Rasayan

Properties of Gandhak Rasayan

The properties of Gandhak Rasayan are: 

Potential Uses of Gandhak Rasayan for Overall Health

Gandhak Rasayan vati (tablet) and Gandhak Rasayan powder possess various health benefits. Some of its potential benefits are: 

1. Potential Uses of Gandhak Rasayan for Eczema

Clinical trials conducted by Sachin et al., 2017 to investigate the role of Gandhak Rasayan vati in Shushka Vicharchika (Eczema) exhibited good clinical improvement in terms of relieving individual symptoms as well as reducing the severity of the disease. Significant reduction in Daha, Kandu (itching), Ruja (sickness), and Sparshasahatva (burning sensation) was observed. Thus, it might be an effective solution for eczema6

2. Potential Uses of Gandhak Rasayan as an Antimicrobial Agent

infection

Gandhak Rasayan is considered a wide-spectrum antimicrobial agent with anti-fungal and anti-bacterial properties.  Various physicians recommend Gandhak Rasayan vati for the treatment of fungal or viral infection because of its bigger zone of inhibition with fewer side effects and comparatively low cost. The clinical efficacy of Gandhak Rasayan in non-infective post-operative cases was assessed by Kadam et al., 2022. This study2 revealed that various microorganisms that presented resistance to certain tested antibiotics showed good susceptibility to the Gandhak Rasayan. Therefore, Gandhak Rasayan is a versatile ayurvedic medicine that has a wide range of health-benefiting effects. 

3. Potential Uses of Gandhak Rasayan in Infections

skin infections

In a case study, the patient suffering from kushta (Tinea corporis) was treated with Gandhaka Rasayan along with exterior and interior applications of a combination of various oils and vati for 14 days. It has antifungal and antibacterial qualities. It mostly influences Rakta Dhatu and results in Rakta shodhan (purification of blood). Due to its antifungal qualities, it aids in decreasing infection. Additionally, it functions as a rasayan and aids in digestion and skin complexion improvement. Skin problems are treated with sulfur both orally and topically5

4. Potential Uses of Gandhak Rasayan in Vulvitis

Sulpher

Vulvitis is the inflammation of the vulva (soft folds of skin outside the vagina) which can result either from injuries, infection, allergy, or irritants. Verma and his colleague, 2021 evaluated the efficacy of Gandhak Rasayan lotion mixed with Gomutra arka, suddha Tankan in an effective and palatable management of vulvitis.  It was advised to apply lotion on the affected area after the bath for 10 minutes and wash with lukewarm Triphala. The treatment was continued for 15 days in two consecutive months. The results demonstrate a little reduction in the primary vulvitis symptoms and the patches of redness or swelling caused by vulvitis also effectively faded after therapy. Thus, concluding that Gandhak Rasayan may have some potential in the management of vulvitis7

5. Potential Uses of Gandhak Rasayan for Ulcerative Skin Lesions

skin itchiness

Gandhak Rasayan may also help in patients with complications such as ulcerative skin lesions over the legs, hands, and back. A similar case was treated with Gandhak Rasayan tablet (125mg), BD for 15 days, by Dr Dhodapkar in 2018. Patient with discharge and pruritis along with pedal oedema and ulcerative skin lesions. Gandhak Rasayan was prescribed for the reduction of infection and healing of skin lesions. It showed a significant reduction in oedema and partial healing of skin lesions in around 15 days8

I recently read an article which says the use of Gandhak Rasayana may aid in relieving the symptoms of arthritis. Gandhak Rasayana is known for its rejuvenating and anti-inflammatory properties9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

6. Other Potential Uses of Gandhak Rasayan Include

Sulpher

Though there are studies that show the benefits of the herb in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of Gandhak Rasayan on human health.  

How to Use Gandhak Rasayan?

Gandhak Rasayan is used in tablet form for the management and potential treatment of various diseases8. It may also be used in the form of topical agents like lotions mixed with other herbal medicines to treat skin disorders7. Gandhak Rasayan is also used as a powder with different herbal juices2.   

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Gandhak Rasayan

The most common Gandhak Rasayan side effects are loose stools, upset stomach, abdominal cramps, and bloating2. The histopathological analysis of rat models administered with repeated doses of Gandhak Rasayan showed mild hemorrhage in the Kidneys of rats along with mild fatty liver1

In my experience, Gandhak Rasayana may be used to delay the premature greying of hair. Gandhak Rasayana has a proven rejuvenator property10.

Dr. Rajeev Singh, BAMS

Precautions to Take with Gandhak Rasayan

Since there is insufficient information available on the safety and efficacy of Gandhak Rasayan during pregnancy and breastfeeding, it is best to avoid this rasayan in these groups2.  

Interactions with Other Drugs

Though there is no information on the interaction of gandhak rasayan with other drugs, some medications should never be combined.  If you’re using any other prescription or nonprescription (over-the-counter [OTC]) medication, consult your doctor before taking it. 

Also Read: Kalmegh: Uses, Benefits, Side Effects, Precautions & More!

Frequently Asked Questions (FAQs)

What are the side effects of Gandhak Rasayan? 

The side effects of Gandhak Rasayan include loose stool, abdominal cramps, upset stomach, and bloating. Fatty liver and kidney hemorrhage are also some other side effects reported in preclinical studies. 

What are the benefits of Gandhak Rasayan? 

Gandhak Rasayan may help in relieving pain, managing diabetes, respiratory and skin disorders along treating allergies. It may also act as an appetizer and rejuvenator. Gandhak Rasayan may also help in building immunity and positive health. 

Is Gandhak Rasayan safe during pregnancy? 

It is mostly advised to avoid Gandhak Rasayan during pregnancy and lactation. One should always consult a medical health practitioner before taking any herbal drugs. 

What does Gandhak Rasayan consist of? 

Gandhak Rasayan consists of sulfur, cow milk, cinnamon, amala, cardamom, patra, guduchi, vibhitaki, haritaki, shunto, and bringharaj along with sugar and water. 

What are the available forms of Gandhak Rasayan? 

It is available as Gandhak Rasayan powder, which can be formulated as Gandhak Rasayan vati (tablet) and as a topical lotion for skin disorders.  

References

  1. Mundugaru R, Ballal SR, Bhat S, Basavaiah R. Chronic toxicity studies of gandhaka rasayan-A herbo-mineral preparation used in Ayurvedic practice. Journal of Ayurveda and Integrative Medicine. 2021 Oct 1;12(4):673-81. Available from: https://www.sciencedirect.com/science/article/pii/S0975947621001054
  1. Kadam RV, Tajane SG. A clinical study of gandhak rasayan and triphala mashi with reference to anti-microbial agents. Available from:  https://www.researchgate.net/publication/362931598  
  1. Gandhaka, Gamdhaka: 20 definitions,Wisdom library. [Internet] Last updated: 31 December, 2022. [Cited: 2023 Jan 17] Available from: https://www.wisdomlib.org/definition/gandhaka  
  1. M.V.R.Wijayanthamala, Sanjay Kumar, Sarvesh Kumar Sing, B.R. Meena. Pharmaceutico-Analytical Study of Gandhaka Rasayan. International Journal of Ayurveda and Pharma Research. 2016;4(7):78-88. Available  form: https://www.researchgate.net/publication/341130665_PHARMACEUTICO-ANALYTICAL_STUDY_OF_GANDHAKA_RASAYAN?enrichId=rgreq-8cc9ef741fdc37f3ff109f27b2282e94-XXX&enrichSource=Y292ZXJQYWdlOzM0MTEzMDY2NTtBUzo4ODc0NjQzMDI1MDE4OTVAMTU4ODU5OTM4NjYwOQ%3D%3D&el=1_x_2&_esc=publicationCoverPdf   
  1. Chavhan MH, Wajpeyi SM. Management of Dadru Kushta (Tinea corporis) through Ayurveda–A Case Study. International Journal of Ayurvedic Medicine. 2020;11:120-23. Available from: https://www.researchgate.net/profile/Sadhana-Misar-Wajpeyi/publication/344645918_Management_of_Dadru_Kushta_Tinea_corporis_through_Ayurveda-_A_Case_Study/links/5fbb8056a6fdcc6cc65c98ca/Management-of-Dadru-Kushta-Tinea-corporis-through-Ayurveda-A-Case-Study.pdf  
  1. Sachin PK, Dattatray PV, Madhav PS. Role of Gandhak Rasayan in Shushka Vicharchika (eczema). AYUSHDHARA. 2016;4(3):1207-10.Available from: https://core.ac.uk/download/pdf/333809946.pdf  
  1. Anjali AV. A Pilot Study on Ayurveda Management of Vulvitis. Journal of Ayurveda and Holistic Medicine (JAHM). 2021 Sep 4;9(4). Available from:  http://www.jahm.co.in/index.php/jahm/article/view/449
  2. Dhodapkar SP, Kale AB. Composite dietary management with agni chikitsa in malnourished child-case study. Available from:  https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1526552586.pdf
  3. Mundugaru R, Ballal SR, Bhat S, Basavaiah R. Chronic toxicity studies of gandhaka rasayana – A herbo-mineral preparation used in Ayurvedic practice. J Ayurveda Integr Med. 2021 Oct-Dec;12(4):673-681. doi: 10.1016/j.jaim.2021.05.011. Epub 2021 Nov 1. PMID: 34736857; PMCID: PMC8642667. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8642667/
  4. Nair R. GANDHAKA RASAYAN — Benefits, Ingredients, Indications, Dosage, Usage, Preparation, Side Effects, Equivalent Medicines, Research Papers. Ayurveda Blogs, Services and Consultation [Internet]. 2022 Jul 6 [cited YEAR MONTH DAY]. Available from: https://ayurvedapc.blog/2022/07/06/gandhaka-rasayan-benefits-ingredients-indications-dosage-usage-preparation-side-effects-equivalent-medicines-research-papers/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Drumstick Tree (Moringa oleifera): Uses, Benefits and Side Effects By Dr. Rajeev Singh

Introduction

“As long as we are not living in harmony with nature, we cannot expect ourselves to heal.” Have you ever heard about the miracle tree? The drumstick tree or Moringa, is called the miracle tree as every part of it benefits humans and animals. Due to this reason, In Sanskrit, the drumstick tree is called Shobhanjana, meaning auspicious. Other names for the drumstick tree include the horseradish tree (English), Sainjna or Saguna (Hindi) and Akshiva or Haritashaaka (Ayurveda). The scientific name of drumstick tree is Moringa oleifera and it is a member of the Moringaceae family. It is a fast-growing evergreen tree cultivated worldwide from India to Africa and numerous other arid and other tropical countries. The leaves, flowers, seeds and roots of the drumstick trees are edible and are used to prepare a variety of delicious recipes. This “tree of life” has various benefits; let us know more about the uses and benefits of drumstick tree leaves1

Friendly Reminder: The information shared here is for educational purposes only and the reader should consult a registered medical practitioner before implementing any changes to their health routine.

Nutritional Value of Drumstick Tree

The leaves of the drumstick tree are packed with the goodness of carbohydrates, proteins, fats, carotenoids, vitamins A and E and minerals like potassium, calcium, iron, magnesium, etc. The phytochemicals in drumstick tree include flavonoids, phenolic compounds, glucosinolates and carotenoids. The nutritional value of the drumstick plant per 100 grams is given below: 

Based on my observations, I have found that different parts of the drumstick tree, including the leaves, pods, and roots, may possess pain-reducing properties. I recommend considering the use of drumstick as a natural remedy for pain relief7.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Drumstick Tree

Drumstick tree shows numerous scientifically proven properties; some of which are mentioned below1:  

Be careful when consuming Moringa leaves! They contain a high concentration of saponins, which can interfere with the absorption of important minerals like zinc and magnesium. It is important to be mindful of this potential risk and monitor your Moringa leaves intake8.

Dr. Smita Barode, B.A.M.S, M.S.

Potential Uses of Drumstick Tree for Overall Health

Some of the potential benefits of the Drumstick tree are described below: 

1. Potential Uses of Drumstick Tree in Colorectal Cancer

cancer

Cancers of the colon and rectum are the third most lethal cancers affecting both males and females equally. Asmari et al. conducted a review in 2015 stating that Drumstick tree halts the abnormal multiplication of colorectal cells and inhibits the formation and progression of cancer cells2. This effect is attributed due to the presence of eugenol, a polyphenol present in drumstick leaves. This indicates that the consumption of drumsticks may help manage colorectal cancers. Also, the presence of carotenoids and flavonoids may help in exerting a protective effect against cancers. However, to claim these results in humans, we need more studies. Additionally, it is advised to consult a physician for the proper management of colorectal cancer and not consider usage of drumstick trees as a remedy for cancers. 

2. Potential Uses of Drumstick Tree in Hypertension

blood pressure

High blood pressure or hypertension is a condition in which blood flows through the arteries at very high pressure. Direk et al. conducted an animal study3 in 2019 stating drumstick consumption helps in relaxing the arteries and thus helps reduce blood pressure. This states that drumsticks may have the potential to manage hypertension. However, we need more human trials to claim these effects with greater reliability. It is better to take a professional opinion if you suffer from high blood pressure instead of self-medicating. 

3. Potential Uses of Drumstick Tree in Colitis

stomach

Colitis is a condition characterised by inflammation and ulceration in the digestive tract. A review4 by Mohsen et al. done in 2014 states that drumsticks may have the potential to manage colitis by reducing inflammation and ulcers. This effect is attributed to the presence of polyphenols which exert anti-inflammatory and antioxidant properties. Thus, it may be concluded that drumsticks may have the potential to manage colitis. However, we need more human studies to claim these results with greater reliability. Additionally, it is always advised to consult a physician for the proper management of colitis and not rely on self-medication with the drumstick tree. 

4. Potential Uses of Drumstick Tree as an Antibacterial Agent

urinary tract infections

Medicinal plants like the drumstick tree are coming into the limelight as antibacterial agents. Abalaka et al. conducted a study5 in 2012 to test the efficacy of the drumstick trees on different bacteria like E.coli, H.pylori, S.typhi, K.pneumonia, etc. A plant-based chemical called glucosinolate present in the leaves of this tree inhibits the growth of these bacteria; thus drumstick leaves may have the potential to manage bacterial infections caused by the above-mentioned bacteria and help in managing infections like urinary tract infections, typhoid, pneumonia, etc. However, we need more studies to confirm these results in humans. It is recommended to avoid self-medication and consult your physician for the proper management of any bacterial infection. 

5. Potential Uses of Drumstick Tree for Diabetes

diabetes

Diabetes (Type I & II) is a metabolic disorder characterised by an increase in blood glucose due to decreased production or resistance of a hormone called insulin which regulates blood glucose. A review1 conducted by Piyush et al. in 2022 stated that the drumstick tree might have the potential to decrease blood glucose levels. This effect is attributed to polyphenols that inhibit enzymes that break down carbohydrates into simpler sugars and increase blood glucose. Additionally, the antioxidant effect plays an important role in reducing the increased blood glucose. Therefore, the leaves of drumstick tree may have the potential to manage diabetes. However, it is advised not to generalise these results in the management of diabetes. To claim these results and apply them in humans, we need more studies. In addition, you should consult your physician for the proper management of diabetes and not rely on self-medication. 

6. Other Potential Uses of Drumstick Tree

asthma

Though there are studies that show the benefits of Drumstick tree in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of drumstick tree on human health.  

I highly recommend incorporating drumstick tree extracts into your diet, as it might be an exceptional source of vitamin A. This essential nutrient has the potential to safeguard your eye health and stave off deficiencies. Including drumsticks in your meals, especially for your children, is a great step towards maintaining optimal vision and promoting eye health7.

Dr. Rajeev Singh, BAMS

How to Use Drumstick Tree?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Also Read: Pancharishta: Uses, Benefits and Side Effects By Dr. Rajeev Singh

Side Effects of Drumstick Tree

A review1 by George et al. in 2016 stated that drumstick contains high metallic content which can be toxic to humans. Therefore, excessive consumption of drumsticks should be avoided. 

However, if you experience any adverse reactions to the drumstick tree, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Also Read: Banana Leaf: Uses, Benefits, Side Effects By Dr. Smita Barode

Precautions to Take with Drumstick Tree

Consuming Drumstick tree is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions1:  

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Drumstick tree with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking. 

Frequently Asked Questions (FAQs)

What is Drumstick tree scientific name? 

The scientific name of the drumstick tree is Moringa oleifera and it is a member of the Moringaceae family1

Which tree is called the miracle tree? 

The drumstick tree is called the miracle tree1

What is Drumstick tree in Hindi?  

In Hindi, the drumstick tree is called as Sainjna or Saguna. 

Does the Drumstick tree benefit weight loss? 

Yes, intake of the leaves of the Drumstick tree may help in weight loss.

Does the usage of Drumstick tree leaves help in managing jaundice? 

There is no study stating benefits of drumstick leaves to manage jaundice.

References

  1. Al-Asmari, Abdulrahman Khazim et al. “Moringa oleifera as an Anti-Cancer Agent against Breast and Colorectal Cancer Cell Lines.” PloS one vol. 10,8 e0135814. 19 Aug. 2015, doi:10.1371/journal.pone.0135814. available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545797/ 
  2. Aekthammarat, Direk et al. “Moringa oleifera leaf extract lowers high blood pressure by alleviating vascular dysfunction and decreasing oxidative stress in L-NAME hypertensive rats.” Phytomedicine : international journal of phytotherapy and phytopharmacology vol. 54 (2019): 9-16. doi:10.1016/j.phymed.2018.10.023. Available at: https://pubmed.ncbi.nlm.nih.gov/30668387/ 
  3. Mohsen et al. “Anti-inflammatory effect of Moringa oleifera Lam. seeds on acetic acid-induced acute colitis in rats.” Avicenna journal of phytomedicinevol. 4,2 (2014): 127-36. Available at: https://pubmed.ncbi.nlm.nih.gov/25050310/ 
  4. Abalaka M.E., Daniyan S.Y., Oyeleke S.B., Adeyemo S.O. The Antibacterial Evaluation of Moringa oleifera Leaf Extracts on Selected Bacterial Pathogens. J. Microbiol. Res. 2012;2:1–4. doi: 10.5923/j.microbiology.20120202.01. available at: http://article.sapub.org/10.5923.j.microbiology.20120202.01.html 
  5. Suresh S., Chhipa A.S., Gupta M., Lalotra S., Sisodia S.S., Baksi R., Nivsarkar M. Phytochemical Analysis and Pharmacological Evaluation of Methanolic Leaf Extract of Moringa oleifera Lam. in Ovalbumin Induced Allergic Asthma. S. Afr. J. Bot. 2020;130:484–493. doi: 10.1016/j.sajb.2020.01.046. available at: https://www.sciencedirect.com/science/article/pii/S0254629919313572?via%3Dihub 
  6. Mabrouki, Lamia et al. “Cardiac Ameliorative Effect of Moringa oleifera Leaf Extract in High-Fat Diet-Induced Obesity in Rat Model.” BioMed research international vol. 2020 6583603. 27 Feb. 2020, doi:10.1155/2020/6583603. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064870/?report=reader 
  7. Islam Z, Islam SMR, Hossen F, Mahtab-ul-Islam K, Hasan MR, Karim R. Moringa oleifera is a Prominent Source of Nutrients with Potential Health Benefits. Int J Food Sci. 2021;2021:6627265. doi:10.1155/2021/6627265. Available from: https://onlinelibrary.wiley.com/doi/10.1155/2021/6627265
  8. García Milla P, Peñalver R, Nieto G. Health Benefits of Uses and Applications of Moringa oleifera in Bakery Products. Plants. 2021;10(2):318. doi:10.3390/plants10020318. Available from: https://www.mdpi.com/2223-7747/10/2/318

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Acai Berry: Uses, Benefits, Side Effects and More By Dr. Smita Barode

Introduction

“Let food be your first medicine and kitchen be your first pharmacy”. This saying acknowledges the importance of eating healthy and using fruits and vegetables for their health benefits. One fruit that has gained limelight due to its health benefits is the Acai berry. It is a small round berry (usually the size of a grape) obtained from the Acai palm Euterpe oleracea Martius. It is green when immature and ripens to a dark purple colour. This plant is native to south and Central America. In India, it is called ‘kallaa pazham’ and its cultivation is limited to Kerala. Mostly in other parts of India, freeze-dried powder or purées are available. Let us know more about the health benefits of this super berry1

Nutritional Value of Acai Berry

Acai berries are packed with the goodness of dietary fibres, proteins and minerals like potassium, calcium etc. They are rich in fatty acids, especially palmitic, oleic and linoleic acid. The phytochemicals in Acai berries include anthocyanins and proanthocyanidins. The nutritional Value of Acai berry is given below.  

Properties of Acai Berry

Acai berry shows numerous scientifically proven properties; some of which are mentioned below3

Based on some research10, the consumption of acai berries might help improve cognitive function in patients suffering from dementia.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Acai Berry for Overall Health

Some of the potential benefits of Acai berries are described below. 

1. Potential Use of Acai Berry in Non-alcoholic Fatty Liver Disease

liver

Non-alcoholic fatty liver disease (NAFLD) is one of the most predominant liver diseases worldwide. Phenolic compounds, especially those belonging to the anthocyanin class, may help manage NAFLD. Pirrozi et al. in 2020 conducted a review3 that stated that Acai berry, due to a high content of phenolic compounds, may help reduce fat accumulation in the liver and may potentially benefit NAFLD. However, these results are not proven in any animal or human study and should not be generalised for treating NAFLD in humans. 

2. Potential Uses of Acai Berry in Lung Cancer 

lung cancer

Over the past few years, the Indian system of medicine has been formulating different extracts from herbs and seeds for managing cancers of the lung, breast, etc. Martinez et al. conducted a study4 in 2018 that showed that extract from Acai berries showed a protective effect against lung cancer. Additionally, phytochemicals like anthocyanins reduce the spread of cancer to other parts of the body. This shows that Acai berries may have the potential to manage lung cancer. However, further research is needed to ascertain these claims as the scientific evidence available is insufficient to claim these results in human beings. 

3. Potential Uses of Acai Berry to Manage Cholesterol Levels

cholesterol

Hypercholesterolemia is elevated blood cholesterol levels and is considered a risk factor for heart disease. Melina et al. conducted a study5 in 2009 showing that Acai berry consumption potentially impacted cholesterol levels in an animal model. These astonishing results show the importance of Acai berry in lowering blood cholesterol and thus, its potential to exert a protective effect on the heart. However, we need human trials to support these claims. 

4. Potential Uses of Acai Berry in Inflammation

inflammaation

Inflammation is a part of the body’s defence mechanism, which helps remove harmful and foreign substances from the body and helps in the healing process. Ulcerative colitis and Crohn’s disease are two conditions characterised by inflammation of the intestines, which are clinically shown as symptoms like abdominal pain, diarrhoea, fatigue, weight loss, etc. A study6 by Kim et al. in 2011 assessed the potential of Acai berries in intestinal inflammation. The presence of anthocyanins in Acai berries helped in reducing inflammation. Thus, it can be concluded that Acai berries may potentially manage inflammation and can be used to manage intestinal inflammatory diseases. However, we need more scientific evidence to support these claims in humans. 

5. Potential Uses of Acai Berry for Blood Glucose

regulates blood sugar

Blood glucose is the main sugar found in the blood and is produced by the breakdown of food that we eat. Udani et al. conducted a study7 in 2011 showing that Acai berry helps reduce blood glucose and improve insulin (a hormone that regulates blood glucose) sensitivity. These astonishing results show the importance of Acai berry in lowering blood glucose levels and thus, its potential to manage diabetes. However, we need human trials to support these claims. 

6. Other Potential Uses of Acai Berry

wound healing

Though there are studies that show the benefits of Acai berry in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of acai berry on human health.  

According to some studies11, acai berry extracts might have some anti-oxidative effects due to the presence of some phenolic compounds, which might be beneficial in oral wound healing.

Dr. Rajeev Singh, BAMS

How to Use Acai Berry?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Acai Berry

Data from the Natural Medicines comprehensive database from 2020 states that raw Acai berry juice consumption can lead to a disease known as American trypanosomiasis or Chagas disease. This only happens when Acai berry is contaminated with the parasite Trypanosoma cruzi. Chagas disease is characterised by the issues of the heart and digestive system. 

However, if you experience any adverse reactions to Acai berries, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms9

Also Read: 8 Great Benefits of Sapota or Chikoo

Precautions to Take with Acai Berry

Consuming Acai berry is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions: 

Also Read: Strawberry: Uses, Benefits, Side Effects By Dr. Smita Barode

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Acai berry with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking. 

Frequently Asked Questions (FAQs)

What is Acai berry? 

Acai berry is a small round berry (usually the size of a grape) obtained from the Acai palm Euterpe oleracea Martius1

How is Acai berry available in the market? 

In the market, Acai berry freeze-dried powder or purées are available1

What is Acai berry in India called as?

In India, Acai berry is called ‘kallaa pazham’. 

Does Acai berry benefits weight loss? 

Yes, Acai berries may help in weight loss5

What are the side effects of Acai berry? 

The Natural Medicines comprehensive database, 2020 states that raw Acai berry juice consumption can lead to a disease known as American trypanosomiasis or Chagas disease. This only happens when Acai berry is contaminated with a parasite Trypanosoma cruzi, Chagas disease is characterised by heart and digestive issues9

References

  1. N Marcason W. What is the açaí berry and are there health benefits? J Am Diet Assoc. 2009 Nov;109(11):1968. doi: 10.1016/j.jada.2009.09.017. PMID: 19857637. Available at: https://www.jandonline.org/article/S0002-8223(09)01606-X/fulltext 
  2. Acai Berry Powder by Health Matters America Inc. Acai berry powder by HEALTH MATTERS AMERICA INC. nutrition facts and analysis. Available at: https://www.nutritionvalue.org/Acai_berry_powder_by_HEALTH_MATTERS_AMERICA_INC._1064123_nutritional_value.html?size=100%2Bg (Accessed: January 19, 2023).  
  3. Pirozzi, Anna Virginia Adriana et al. “Antioxidant and Hypolipidemic Activity of Açai Fruit Makes It a Valuable Functional Food.” Antioxidants (Basel, Switzerland) vol. 10,1 40. 31 Dec. 2020, doi:10.3390/antiox10010040. Available at: https://www.mdpi.com/2076-3921/10/1/40 
  4. Martinez, Raquel Martins et al. “Açai (Euterpe oleracea Mart.) Seed Extract Induces Cell Cycle Arrest and Apoptosis in Human Lung Carcinoma Cells.” Foods (Basel, Switzerland) vol. 7,11 178. 26 Oct. 2018, doi:10.3390/foods7110178. Available at: https://pubmed.ncbi.nlm.nih.gov/30373103/ 
  5. Melina Oliveira et al. “Diet supplementation with acai (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress and the serum lipid profile in rats.” Nutrition (Burbank, Los Angeles County, Calif.) vol. 26,7-8 (2010): 804-10. doi:10.1016/j.nut.2009.09.007. available at: https://pubmed.ncbi.nlm.nih.gov/20022468/ 
  6. Kim, Kyeong Jin et al. “Acai berry extract as a regulator of intestinal inflammation pathways in a Caco-2 and RAW 264.7 co-culture model.” Journal of food biochemistry, e13848. 5 Jul. 2021, doi:10.1111/jfbc.13848. available at: https://pubmed.ncbi.nlm.nih.gov/34227129/ 
  7. Udani, Jay K et al. “Effects of Açai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study.” Nutrition journal vol. 10 45. 12 May. 2011, doi:10.1186/1475-2891-10-45. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118329/ 
  8. ALNasser, Maryam N et al. “A Preliminary Assessment of the Nutraceutical Potential of Acai Berry (Euterpe sp.) as a Potential Natural Treatment for Alzheimer’s Disease.” Molecules (Basel, Switzerland) vol. 27,15 4891. 30 Jul. 2022, doi:10.3390/molecules27154891. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370152/ 
  9. Acai: Overview, uses, side effects, precautions, interactions, dosing and reviews (no date) WebMD. WebMD. (Accessed: January 19, 2023).  Available at: https://www.webmd.com/vitamins/ai/ingredientmono-1109/acai 
  10. Alzheimer’s Drug Discovery Foundation. Açaí Berries. Cognitive Vitality. Updated June 2, 2021. Available from: https://www.alzdiscovery.org/cognitive-vitality/ratings/acai-berries
  11. Kang MH, Kim BH. Oral wound healing effects of acai berry water extracts in rat oral mucosa. Toxicological Research. 2018;34(2):97–102. doi:10.5487/TR.2018.34.2.097. Available from: https://link.springer.com/article/10.5487/TR.2018.34.2.097

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Madhunashini (Gymnema Sylvestre): Uses, Benefits and Side Effects By Dr. Smita Barode

Introduction

“Ayurveda, a most sacred science of life, is beneficial to humans both in this world and the world beyond”. Ayurveda focuses on improving human health and well-being through herbs and spices. One such herb which is of great significance is Madhunashini. Madhunashini is also known as meshashringi (Sanskrit), gurmar and merasingi (Hindi), vakundi, kavuli and kalikardori (Marathi), dhuleti and mardashingi (Gujarathi), Podapatri (Telugu) and Cherukurinja (Tamil). The scientific or botanical name of Madhunashini is Gymnema sylvestre and it belongs to the Asclepiadaceae family. It is a medicinal woody climber native to western and Central India, Australia, and tropical Africa. In India, it is widely grown in Bihar, Chhattisgarh Andhra Pradesh, Kerala, Karnataka, Uttar Pradesh, Madhya Pradesh, and West Bengal. The leaves, flowers, and root extracts have medicinal properties. Let us know more about the health benefits of this wonder plant1,2.

Nutritional Value of Madhunashini

Madhunashini has nutrients like carbohydrates, proteins, and other phytochemical constituents like saponins, sterols, terpenoids, glycosides, alkaloids, resins, etc3.

Did you know?

  • A study showed that Madhunashini extract improved insulin sensitivity in patients with type 2 diabetes. source: ncbi
  • Research suggests that Madhunashini may help reduce the risk of diabetic complications such as neuropathy and nephropathy. source: diabetesjournals.org

Properties of Madhunashini

Scientifically proven properties of Madhunashini include1:

Based on my experience, I have found that the leaf extract of madhunashini might have antiarthritic effects. The extract contains certain compounds that could potentially inhibit inflammation and reduce the release of pain-causing substances, which may help in managing arthritic symptoms8.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Madhunashini for Overall Health

Some of the potential benefits of Madhunashini are described as under:  

1. Potential Uses of Madhunashini in Diabetes

Home Remedies For Diabetes
Image Source: freepik.com

We can’t deny that diabetes is one of the most common diseases, showing an increasing trend worldwide. Even in their 20s, youngsters have complaints of high blood glucose levels because of unhealthy dietary choices and a sedentary lifestyle. A review1 by Kanetkar et al. in 2007 stated that Madhunashini exerts anti-diabetic effects due to the presence of gymnemic acids. The possible mechanism attributed is an increase in insulin secretion, a hormone that regulates blood glucose. Additionally, gymnemic acids help inhibit glucose absorption from the intestine and increase glucose utilization. This indicates that Madhunashini may help manage diabetes. However, more studies are needed to support these claims with greater reliability1.

2. Potential Uses of Madhunashini for Lipid Profile

Cholesterol normal range
Image Source: freepik.com

A lipid profile is a blood test that measures the number of triglycerides and cholesterol in the blood. An altered lipid profile is a risk factor for diseases like atherosclerosis, pancreatitis, etc. Eisenberg et al. 2003 conducted a study8 in rats. This study showed that Madhunashini leaf extracts could reduce serum triglycerides, low-density lipoprotein, total cholesterol, etc. This indicates that Madhunashini has the potential to correct an abnormal lipid profile. However, these results are based on animal studies and more studies are needed to claim these effects in humans4.

3. Potential Uses of Madhunashini in Obesity

Image Source: freepik.com

Obesity is a complex disease characterized by excess body fat, which can negatively affect health. Studies have supported the fact that using food sources in the right quantity and the use of complementary and alternative medicine like yoga and ayurvedic herbs may help in weight loss. A review4 conducted by Fabio et al. in 2013 stated that Madhunashini has the potential to manage obesity. This effect is attributed to inhibiting taste perception by gymnemic acids present in Madhunashini leaf and root extracts which may limit your food intake. This indicates that the Madhunashini may aid weight loss by decreasing the intake of calories. However, we need more studies to support these claims with greater reliability4,5

4. Potential Uses of Madhunashini in Cancer

cancer
Image Source: freepik.com

Cancer is a disease in which cells of the body may multiply abnormally and form cancerous cells that may spread to other parts of the body. A review4 conducted by Fabio et al. in 2013 states that Madhunashini may help manage breast and lung cancer. The exact mechanism behind this effect is, however, still being determined. This indicates that Madhunashini may help with cancer. However, scientific evidence supporting these claims is limited. Therefore, we need more studies to support these claims4.

5. Potential Uses of Madhunashini as an Antibacterial Agent

infection
Image Source: freepik.com

Many antibacterial agents in Ayurveda have been used for managing bacterial infections; one such agent is Madhunashini. A review4 conducted by Fabio et al. in 2013 stated that Madhunashini leaf extract might have antibacterial activity against bacteria like E.coli and Salmonella species. By killing these bacteria, Madhunashini may help manage urinary tract infections, diarrhoea, typhoid, etc. This indicates that it may help manage a wide range of bacterial infections. Additionally, it may also help in managing dental caries, usually caused by bacteria, and thus may help improve dental hygiene. However, there is no scientific study done on humans to support these claims4.

6. Other Potential Uses of Madhunashini

constipation
Image Source: freepik.com

Though there are studies that show the benefits of Madhunashini in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of Madhunashini on human health.  

In my experience, madhunashini extract may have potential benefits in wound healing. The extract contains flavonoids, which are known for their antioxidant properties. While further studies are needed, incorporating its extract in wound care may support the healing process8.

Dr. Rajeev Singh, BAMS

How to Use Madhunashini?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Did you know that the root bark of Madhunashini has been historically used as an emetic, expectorant, and analgesic for body aches? It has also been utilized as a traditional remedy for snakebites, with the root juice playing a role in its treatment8.

Dr. Smita Barode, B.A.M.S, M.S.

Side Effects of Madhunashini

However, if you experience any adverse reactions to Madhunashini, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Also Read: Gokshuradi Guggulu: Uses, Benefits, Side Effects and more!

Precautions to Take with Madhunashini

Consuming Madhunashini is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions7

Also Read: Vasaka (Malabar Nut): Uses, Benefits and Side Effects by Dr. Rajeev Singh 

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of Madhunashini with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking7.

Also Read: Triphala: Uses, Benefits, Side Effects & More!

Frequently Asked Questions (FAQs)

What is Madhunashini also known as? 

Madhunashini is also known as meshashringi (Sanskrit), gurmar and merasingi (Hindi), vakundi, kavuli and kalikardori (Marathi), dhuleti and mardashingi (Gujarathi), Podapatri (Telugu) and Cherukurinja (Tamil)1.

What is the scientific name of the Madhunashini plant? 

The scientific name of the Madhunashini plant is Gymnema sylvestre, which belongs to the Asclepiadaceae family1.

Does Madhunashini interact with food?  

No, there are no interactions of Madhunashini with food7.

Is Madhunashini available in the market? 

Yes, it is available in the market as Madhunashini tablet, capsules, extract, powder, paste, etc6.

What is Madhunashini called in Tamil? 

Madhunashini in Tamil is known as Cherukurinja1.

References

  1.  Kanetkar, Parijat et al. “Gymnema sylvestre: A Memoir.” Journal of Clinical Biochemistry and Nutrition vol. 41,2 (2007): 77-81. doi:10.3164/jcbn.2007010. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170951/
  1. Pandey, Ashok Kumar and Swati Yadav. “Variation in gymnemic acid content and non-destructive harvesting of Gymnema sylvestre (Gudmar).” Pharmacognosy research vol. 2,5 (2010): 309-12. doi:10.4103/0974-8490.72330. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093035/ 
  1. Khan, Farzana et al. “Comprehensive Review on Phytochemicals, Pharmacological and Clinical Potentials of Gymnema sylvestre.” Frontiers in pharmacology vol. 10 1223. 29 Oct. 2019, doi:10.3389/fphar.2019.01223. Available at: https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2019.01223/full
  1. Di Fabio G, Romanucci V, Zarrelli M, Giordano M, Zarrelli A. C-4 Gem-Dimethylated Oleanesof Gymnema sylvestre and Their Pharmacological Activities. Molecules. 2013; 18(12):14892-14919. Available at: https://www.mdpi.com/1420-3049/18/12/14892 
  1. Lin, Xihua and Hong Li. “Obesity: Epidemiology, Pathophysiology and Therapeutics.” Frontiers in endocrinology vol. 12 706978. 6 Sep. 2021, doi:10.3389/fendo.2021.706978. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450866/ 
  1. Saneja A, Sharma C. Gymnema sylvestre (Gurmar): a review. Der Pharmacia lettre [Internet]. 2010;2(1):275–84. Available from: https://www.scholarsresearchlibrary.com/articles/gymnema-sylvestre-gurmar-a-review.pdf 
  1. Medlineplus. Gymnema [Internet]. Vol. 2, MedlinePlus National Library of Medicine. 2021. Available from: https://medlineplus.gov/druginfo/natural/841.html 
  2. Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of *Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014;2014:830285. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3912882/
  3. Preuss, H. G., Jarrell, S. T., Scheckenbach, R., Lieberman, S., & Anderson, R. A. (1998). Comparative effects of chromium, vanadium and Gymnema sylvestre on sugar-induced blood pressure elevations in SHR. Journal of the American College of Nutrition, 17(2), 116–123. doi:10.1080/07315724.1998.10718736. PMID: 9550454. Available from: https://pubmed.ncbi.nlm.nih.gov/9550454/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Talmakhana: Uses, Benefits and Side Effects by Dr. Smita Barode 

Introduction

The Indian system of medicine, i.e. Ayurveda, teaches us how to cherish mother nature. Ayurvedic herbs and spices play an important part in promoting health and wellness. One such herb which has gained limelight during these years is talmakhana, a special category of drugs classified under Rasayana. Talmakhana finds mention in ancient books like “Charak Samhita” and “Sushruta Samhita.” Talmakhana is the bitter seed obtained from the Asteracantha longifolia (L.) Nees. In the Unani system of medicine, these seeds are called talmakhana, whereas in Ayurvedic medicine, they are called kokilaksha (having eyes like kokila or Indian cuckoo). The other vernacular names of Talmakhana include Iksura (Sanskrit), Golmidi (Tamil), Ekharo (Gujarati) and Nirmuli (Malayalam). This plant is widely cultivated in India, Sri Lanka, Malaysia and Nepal. Let’s read more about the health benefits of talmakhana and some common considerations which you need to keep in mind before adding talmakhana to your diet1

Nutritional Value of Talmakhana

Talmakhana is packed with the goodness of minerals like sodium, magnesium, potassium, calcium, iron, chromium, copper, zinc, nickel, cadmium, etc. The nutritional chart of talmakhana is given below2.  

Studies8 have revealed that Talmakhana may be used to tackle symptoms of gout. In my experience, Talmakhana is known for its caustic, bitter, aphrodisiac, tonic, sedative and anti-inflammatory nature that is used to manage blood disorders.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Talmakhana

Talmakhana show numerous scientifically proven properties; some of which are mentioned below1

Potential Uses of Talmakhana for Overall Health

Some of the potential benefits of talmakhana are described below: 

1. Potential Uses of Talmakhana for the Liver

liver

Ever wondered what happens to the medicines like paracetamol once we eat it or what our body does with medicines? The liver is the organ responsible for converting these medicines into a non-toxic form that can be removed from the body. If the liver fails in its function, these drugs, like paracetamol, may accumulate in the body and can result in toxicity. Handa et al. conducted a study2 in 1999 to assess the effect of talmakhana on the liver. The findings of this study showed that talmakhana seeds had a hepato-protective effect against paracetamol poisoning in rats. The results of this study indicate that talmakhana may protect the liver against paracetamol poisoning. However, we need more scientific evidence to support these claims in humans. 

2. Potential Uses of Talmakhana in Liver Cancer

liver cancer

Carcinogenesis is the abnormal and uncontrolled growth of cells, resulting in the formation of cancer. Over the past few years, the Indian system of medicine has been formulating different extracts from herbs and seeds like talmakhana for managing cancers. Ahmed et al. conducted an animal study3 in 2010 which showed that talmakhana seeds helped inhibit liver carcinogenesis in rats. This shows that talmakhana may have the potential to manage liver cancer. However, further research is needed to ascertain these claims as the scientific evidence available is insufficient to claim these results in human beings.

3. Potential Uses of Talmakhana for Blood Glucose Level

regulates blood sugar

Blood glucose is the main sugar that is found in your blood. It comes from the food you eat and is the main energy source for the body. Fernando et al. conducted an animal study4 in 1991, showing that talmakhana stimulates the liver and muscles to take up glucose from the blood and store it as glycogen. These astonishing results show the importance of talmakhana in lowering blood glucose levels and thus, its potential to manage diabetes. However, we need human trials to support these claims. 

4. Potential Uses of Talmakhana as an Antibacterial Agent

bhadrasana for management of stress urinary incontinence in women

Burkholderia pseudomallei are bacteria known to cause melioidosis or Whitmore’s disease. It is known to affect both humans and animals. This bacterium is found in contaminated food and water. The symptoms of melioidosis include fever, stomach, chest and joint pain, headache and weight loss. A review by Samy et al. in 2005 stated5 that talmakhana might help inhibit the growth of Burkholderia pseudomallei and reduce the infections caused by them. Thus, talmakhana is a potential antibacterial agent against Burkholderia pseudomallei. Traditionally, it has been used as a potent antibacterial agent against urinary tract infections. However, we need more scientific evidence to support these claims in humans.

5. Potential Uses of Talmakhana for the Heart and Kidney

heart

Excessive fluid accumulation in the body or oedema can result in high blood pressure and heart problems like heart failure. A review carried out by Nagendra et al. in 2010 suggested that talmakhana can exert a diuretic effect1. This effect causes the kidneys to increase urine formation by removing excess fluid and salt from the body. This helps in reducing blood pressure and fluid overload leading to heart failure. Thus, talmakhana may help in managing high blood pressure and heart failure. Additionally, talmakhana may also help treat urinary stones. However, to support these claims in humans, more studies are required. 

6. Other Potential Uses of Talmakhana

jaundice

Though there are studies that show the benefits of talmakhana in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of talmakhana on human health.  

I read an article that suggests that Talmakhana may be used to relieve gallstones and kidney stones. The ‘ashmari’ property of Talmakhana is well known and makes Talmakhana a potential aid for managing gallstones8.

Dr. Rajeev Singh, BAMS

How to Use Talmakhana?

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.   

Side Effects of Talmakhana

The side effects of talmakhana are minimal. Ajana et al. conducted a review6 in 2013 which stated that depending on the prakriti (human constitution), few individuals can be allergic to talmakhana and can show allergic reactions characterised by a runny nose, wheezing, rashes, etc. 

However, if you experience any adverse reactions to talmakhana, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Precautions to Take with Talmakhana

Consuming talmakhana is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions: 

Interactions with Other Drugs

However, you must always seek the advice of your Ayurvedic physician about the possible interaction of talmakhana with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking. 

Also Read: Psyllium Husk (Isabgol): Uses, Benefits & Side Effects

Frequently Asked Questions (FAQs)

What is the talmakhana plant? 

Talmakhana is the bitter seed obtained from the plant Asteracantha longifolia (L.) Nees.

Is talmakhana and kokilaksha same? 

Yes, In the Unani system of medicine, the seeds of the plant Asteracantha longifolia are called talmakhana, whereas, in Ayurvedic medicine, they are called kokilaksha.

Does talmakhana benefit hair growth?  

No, there are no benefits of talmakhana for hair growth. 

What precautions must be taken when consuming talmakhana? 

It is advised to always purchase ayurvedic medicines which are assessed for their quality and efficacy. Check for the labels of these products and do not buy talmakhana seeds in loose, as these are adulterated with seeds of R.tuberosa, which is poisonous. The safety of talmakhana in elderly, children, pregnant and lactating women is not well-established. Therefore, necessary cautions must be taken. It is always advised to consult a physician if you plan to consume talmakhana.

What are the side effects of talmakhana? 

The side effects of talmakhana are minimal. Ajana et al. conducted a review7 in 2013 which stated that depending on the prakriti (human constitution), few individuals can be allergic to talmakhana and can show allergic reactions characterised by a runny nose, wheezing, rashes, etc. 

References

  1. Nagendra et al. Asteracantha longifolia (L.) Nees, Acanthaceae: chemistry, traditional, medicinal uses and its pharmacological activities – a review, Rev. Bras. Farmacogn. Braz. J. Pharmacogn. 20(5): Out./ Nov. 2010. Available at: https://www.readcube.com/articles/10.1590/s0102-695×2010005000022 
  2. Nigam V, Mishra RK, Gupta A, Bhati MK. Pharmacognostic study, characterization of marker compounds and pharmacological review of aerial parts of Hygrophila auriculata (Schumach.) Heine. World J Pharm Pharm Sci. 2015;4(12):1127–1143. Available from: https://www.researchgate.net/publication/335715529_PHARMACOGNOSTIC_STUDY_CHARACTERIZATION_OF_MARKER_COMPOUNDS_AND_PHARMACOLOGICAL_REVIEW_OF_AERIAL_PARTS_OF_HYGROPHILA_AURICULATA_SCHUMACH_HEINE
  3. Malpotra M, Garg M, Singh N, Dey Sadhu S, Chopra R, Sharma B. An overview of bioactive components and phytopharmaceutical potentials of Hygrophila auriculata – A herbaceous medicinal plant. Phytomedicine Plus. 2025;5(1):100737. doi:10.1016/j.phyplu.2025.100737. Available from: https://www.sciencedirect.com/science/article/pii/S2667031325000107
  4. Nawaz A, Zhang P, Li E, Gilbert RG, Sullivan MA. The importance of glycogen molecular structure for blood glucose control. iScience. 2020 Dec 16;24(1):101953. doi: 10.1016/j.isci.2020.101953. PMID: 33458612; PMCID: PMC7797522. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7797522/
  5. Ross BN, Myers JN, Muruato LA, Tapia D, Torres AG. Evaluating New Compounds to Treat Burkholderia pseudomallei Infections. Front Cell Infect Microbiol. 2018 Jun 25;8:210. doi: 10.3389/fcimb.2018.00210. PMID: 30013953; PMCID: PMC6036294. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6036294/
  6. Kshirsagar AD, Ingale KG, Vyawahare NS, Thorve VS. Hygrophila spinosa: A comprehensive review. Pharmacogn Rev. 2010 Jul;4(8):167-71. doi: 10.4103/0973-7847.70912. PMID: 22228957; PMCID: PMC3249917. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3249917/
  7. Karthik KP, Dileep A, Rajagopala S, Arun Kumar M, Dharmarajan P, Vellela J. Ayurvedic clinical decision‑making methods to predict, prevent and manage childhood allergic disorders. J Ayurveda Integr Med. 2024;15(1):100857. doi:10.1016/j.jaim.2023.100857.https://pubmed.ncbi.nlm.nih.gov/38237455/
  8. Sharma U, Singh S, Rani S, Mitra S, Sharma KC. Review on spermatogenic activity of Gokshuradi Churna. Sch Int J Tradit Complement Med. 2023;6(5):75–79. doi:10.36348/sijtcm.2023.v06i05.001. Available from: https://saudijournals.com/media/articles/SIJTCM_65_75-79.pdf
  9. Prashanth BK. Kokilaksha Asteracantha longifolia: uses, research, side effects, remedies [Internet]. Easy Ayurveda; 2017 Mar 7 [cited 2026 Jan 8]. Available from: https://www.easyayurveda.com/2017/03/07/kokilaksha-asteracantha-longifolia/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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What Happens To Your Lungs From Smoking? Things You Should Know

Introduction

You’ve probably heard of this disclaimer on multiple occasions – ‘smoking is injurious to health’. What you may not immediately realise is the extent of the damage smoking can cause to your health and, most directly, your lungs.

Smoking is known to be the leading cause of preventable diseases and deaths globally. Nearly all forms of lung cancer, the top cause of cancer death in both men and women, can be attributed to smoking. Tobacco and tobacco-related products can damage the lungs’ ability to supply oxygen to the body. Other substances commonly found in cigarette smoke can cause permanent lung damage, even in small amounts.

How Smoking Changes Your Lungs

A single puff of cigarette smoke contains upwards of 7,000 chemicals. Tobacco smoke contains over 70 known cancer-causing chemicals2. When you breathe these in, these toxins go deep into your lungs and can cause swelling, resulting in a host of other respiratory diseases.

Both tobacco and chemical substances found in cigarettes can change the cellular structure of the lungs. They can cause the elastic walls within the airways to break down – resulting in less functioning surface area in the lungs. Cigarettes can damage lung tissue, preventing them from functioning correctly. This can increase the risk of diseases caused by smoking, such as chronic bronchitis, emphysema, respiratory diseases, asthma and COPD (Chronic Obstructive Pulmonary Disease)1.

Nicotine in tobacco can also damage the ability of the respiratory system to filter out dust and dirt. This can lead to toxic substances passing through, resulting in lung congestion and the ‘smoker’s cough’.

Repercussions of Long-term Smoking

A person who smokes throughout life is at high risk of developing a range of potentially fatal diseases owing to impaired lung function and breathlessness due to swelling and narrowing of the lung airways and excess mucus build-up. They are also prone to weakening the lungs’ clearance system, leading to the accumulation of toxic substances and causing lung irritation and damage. Further, they are also at an increased risk of lung infection, chronic bronchitis and heightened risk of asthma, along with permanent damage to air sacs3.

In the longer term, smoking is known to induce heart disease and stroke, in certain cases, it can cause ulcers of the digestive system and put smokers at increased risk of type 2 diabetes.

Most smokers are also likely to develop emphysema. The number of cigarettes you smoke and other lifestyle factors may impact the extent of the damage. If you’re diagnosed with either of these respiratory diseases – emphysema or chronic bronchitis, you run the risk of being diagnosed with chronic obstructive pulmonary disease (COPD).

Also Read: Does Smoking Really Affect Your Brain?

Beyond Lung Damage: Diseases Caused by Smoking

Smoking can affect a person’s health in other ways, too, harming almost every organ in the body. In most cases, it can result in a compromised immune system function, making you susceptible to many other illnesses. It can also lead to lower bone density (brittle bones), which increases the risk of broken bones and fractures. Smoking also leaves you at a higher risk of rheumatoid arthritis, heart disease and stroke, along with an increased risk for cataracts (clouding of the eye lenses).

Apart from respiratory diseases, other visible disorders include an increased risk of oral cancers, gum disease and tooth loss, premature ageing of the skin, bad breath and stained teeth and an increased risk for age-related macular degeneration, which can lead to blindness. Moreover, even your wounds may take longer to heal!

Also Read: 6 Simple Exercises to Improve Your Lung Health

How Quitting Can Benefit Your Lungs

It’s never too late to quit smoking. Within days of quitting smoking, lungs begin to repair themselves. In fact, just 12 hours after you quit, the amount of carbon monoxide in your blood drops to a much healthier level. More oxygen flows to your vital organs and you will be able to breathe better. In about 10 to 15 years, your risk of developing lung cancer reduces and may even become the same as a non-smoker4.

Also Read: How to Avoid Asthma Attacks During Winter

References

1. Centers for Disease Control and Prevention (US); National Center for Chronic Disease Prevention and Health Promotion (US); Office on Smoking and Health (US). How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General. Atlanta (GA): Centers for Disease Control and Prevention (US); 2010. 7, Pulmonary Diseases. Available from: https://www.ncbi.nlm.nih.gov/books/NBK53021/

2. National Cancer Institute. Harms of Cigarette Smoking and Health Benefits of Quitting [Internet]. Bethesda (MD): National Cancer Institute; reviewed 19 December 2017 [cited 2025 Sep 19]. Available from: https://www.cancer.gov/about-cancer/causes-prevention/risk/tobacco/cessation-fact-sheet

3. Varghese J, Muntode Gharde P. A Comprehensive Review on the Impacts of Smoking on the Health of an Individual. Cureus. 2023 Oct 5;15(10):e46532. doi: 10.7759/cureus.46532. PMID: 37927763; PMCID: PMC10625450. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10625450/

4. Centers for Disease Control and Prevention. Benefits of Quitting Smoking [Internet]. Atlanta (GA): CDC; updated May 15, 2024 [cited 2025 Sep 19]. Available from: https://www.cdc.gov/tobacco/about/benefits-of-quitting.html

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Eucalyptus Oil: Uses, Benefits, Side Effects By Dr. Smita Barode

Introduction

Aromatic herbs are being widely used, especially in rural areas. Eucalyptus is one such aromatic oil that has seen an increase in its use in developing countries. 

Eucalyptus oil, also known as nilgiri oil, is an essential oil derived from the distillation of fresh leaves of Eucalyptus globulus and other species like E. polybractea, E. smithii, and E. viminalis, belonging to the family Myrtaceae. This tall evergreen tree is native to Tasmania and Australia. Further, it is found in Spain, the United States, Brazil, Portugal, North and South Africa, France, Southern Europe, and India. In India, it is majorly cultivated in Punjab and Haryana. 

It is a straw-coloured or colourless fluid with a characteristic smell that may be described as camphor-like and pungent, and its taste is also said to be camphoraceous, followed by a cooling sensation. Let’s read about eucalyptus oil’s benefits and side effects1.

Did you know?

Nutritional Value of Eucalyptus Oil

Eucalyptus oil is known for its wide variety of bioactive compounds. They are enlisted below: 

Chemical constituents of Eucalyptus oil1.

A total of 0.26% of eucalyptus oil constituents are unknown.  

Based on my experience, I have observed that eucalyptus oil might possess hepatoprotective properties. This means that it could potentially protect the liver from damage caused by certain toxins. It is believed to involve the presence of ursolic acid, a compound found in the leaves of Eucalyptus hybrid E. tereticomis. Ursolic acid is known to have antioxidant and anti-inflammatory properties, which may contribute to its ability to protect the liver cells from damage and promote their regeneration12.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Eucalyptus Oil

Eucalyptus oil has many treasures hidden within it. Some of the properties of eucalyptus essential oil are1

In my experience, I have observed that eucalyptus oil might be beneficial for relieving spasmodic throat troubles, such as in croup. When applied externally, it may help alleviate the spasms and provide relief12.

Dr. Rajeev Singh, BAMS

Potential Uses of Eucalyptus Oil for Overall Health

The potential benefits of eucalyptus oil for your health are: 

1. Potential Uses of Eucalyptus Oil for Urinary Tract Infection

urinary tract infections
Image Source: freepik.com

In a study14 done by Moreira in 2001, eucalyptus oil may help in treating urinary tract infections. It may be used in an emulsion mixture with powdered gum arabic and water. This mixture may be given as urethral injections. However, a doctor should be consulted before using nilgiri oil1.

2. Potential Uses of Eucalyptus Oil for Diabetics

Home Remedies For Diabetes
Image Source: freepik.com

Eucalyptus essential oil has shown potential anti-diabetic properties. In a comparative study8 in 1998 by Gray, they observed the effects of eucalyptus for management of diabetes by partial restoration of pancreatic cells in rats. Further, Dey observed that eucalyptus citriodora showed potential anti-diabetic activity that was analogous to the standard diabetes drug Glibenclamide. Although, this won’t replace the medication prescribed by your doctor, you should consult a doctor before using eucalyptus oil for diabetes1,2.

3. Potential Uses of Eucalyptus Oil for Respiratory Diseases

respiratory disease
Image Source: freepik.com

Sonker et. al in a study9 in 2017 observed that eucalyptus oil may potentially relieve symptoms of respiratory diseases. It was reported in a study that major constituents of this essential oil may relieve coughing, stimulate breathing, relax the respiratory muscles and remove mucus. Further, it may help in sore throat, runny nose, cough, cold, asthma, bronchitis, sinusitis, and nasal congestion. Nilgiri oil can help in reducing the symptoms but should not be replaced with conventional treatment without consulting your doctor1.

4. Potential Uses of Eucalyptus Oil for Wound Healing

wound healing
Image Source: freepik.com

In a study10 in 1994, Sarkar found sores, cuts, scrapes, abrasions, burns and wounds may be benefitted using eucalyptus leaf essential oil. It can be used in the form of an ointment or salve to potentially use on bug bites and stings. In a study by Sabo in 2019, extracts of eucalyptus species showed a probable reduction in the size of acetic acid-induced ulcers in rats. Therefore, it may be a possibility that eucalyptus oil can be used for wound healing. You should consult a doctor before using eucalyptus oil on your wounds1.

5. Potential Uses of Eucalyptus Oil in Pain Relief

osteoarthritis
Image Source: freepik.com

Maruyama11 in 2005 observed that aromatherapy massage potentially suppresses the inflammatory symptoms of oedema and neutrophil accumulation. This is because eucalyptus oil is volatile and hence, gets easily absorbed into the muscle and nerve. It has a property to reduce pain (analgesic). Eucalyptus may help in case of chronic pain along with conventional medication. Eucalyptus oil should not be traded for your medication without consulting your doctor1,2.

6. Other Potential Uses

Image Source: freepik.com

Other than the above-noted uses of eucalyptus, they are also some other eucalyptus oil uses and benefits, such as: 

Though there are studies that show the benefits of the eucalyptus oil in various conditions, these are insufficient and there is a need for further studies to establish the true extent of benefits of eucalyptus oil on human health.  

For both chemical and natural techniques, the chosen eucalyptus oil is a unique kind. An ingredient in the oil of lemon eucalyptus (OLE) is known to repel mosquitoes and other insects. I recommend the use of eucalyptus oil under the doctor’s supervision13.

Dr. Smita Barode, B.A.M.S, M.S.

How to Use Eucalyptus Oil?

Eucalyptus oil may be used in a number of ways to treat different conditions. Some ways to use eucalyptus oil are:  

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor. 

One essential component of various topical analgesics is eucalyptus. These include creams, salves, sprays, and other topical painkillers that you may apply straight to your skin. From my knowledge, eucalyptus oil works by creating a cool or warm sensation that may distract you from the pain, even if it is not the primary painkiller13.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

Side Effects of Eucalyptus Oil

Like most essential oils, eucalyptus oil also has many side effects. The most common eucalyptus oil side effects are:  

Also Read: The Truth about Sunflower Oil: Is it Really Bad for You?

Precautions to Take with Eucalyptus Oil

You now know that eucalyptus oil should not be consumed by itself. Some other precautions to be taken with eucalyptus oil include: 

Also Read: 6 Simple Health Benefits of Essential Oils!

Interactions with Other Drugs

Eucalyptus is generally considered safe for topical use. However, it should never be consumed orally, especially without dilution with some other ingredients. It is considered toxic when consumed orally and may interact with your medications. Eucalyptus oil may affect the metabolic activity of the liver and thus, may disrupt the metabolism of certain drugs6

If you are consuming any drug that may be metabolized by the liver, contact your general physician before using eucalyptus oil. For instance, 5-fluorouracil (5-FU) is a medication used to treat cancer. It was observed in an animal study that when eucalyptus oil is used on the skin caused an increase in the absorption of topical 5-FU. Further, some diabetic medication also interacts with eucalyptus oil3,6.

Also Read: Tea Tree: Uses, Benefits, Side Effects, and More!

Frequently Asked Questions (FAQs)

Can you use eucalyptus oil to treat colds? 

Yes, the benefits of eucalyptus oil for cold are widely reported. It can be used via inhalation and cough drops. It has expectorant, antispasmodic and antiviral properties.  

Can eucalyptus oil be consumed orally? 

No, eucalyptus oil cannot be consumed orally, especially in large doses. It is usually consumed as a pharmaceutical product or can be used as a topical medication.  

Is eucalyptus oil safe for wound healing? 

Yes, eucalyptus oil can be used for wounds like abrasions, burns, scrapes, cuts and sores. It can be applied as a salve.

Does eucalyptus interact with other drugs? 

Yes, eucalyptus oil can interact with other drugs that get metabolized by the liver as it affects the metabolism rate in the liver. For example, 5-fluorouracil sees an increase in absorption when used topically with eucalyptus oil.  

Can children use eucalyptus oil? 

No, children under the age of one should not be administered eucalyptus oil. Children may be administered eucalyptus oil only after referring to a general physician.  

References

1. Rathva D, Parmar D, Upadhyay S, Upadhyay U. A Basic Review on Eucalyptus Oil. International Journal of Pharmaceutical Research and Applications [Internet]. [cited 2022 Nov 29];5(2):771–81. Available from: https://ijprajournal.com/issue_dcp/A%20Basic%20Review%20on%20Eucalyptus%20Oil.pdf?

2. Dhakad AK, Pandey V v., Beg S, Rawat JM, Singh A. Biological, medicinal and toxicological significance of Eucalyptus leaf essential oil: a review. J Sci Food Agric. 2018 Feb 1;98(3):833–48. Available from: https://pubmed.ncbi.nlm.nih.gov/28758221/ 

3. Dey B, De J, Ghatak S, Maiti K. Chemo-profiling of eucalyptus and study of its hypoglycemic potential. Integr Med Res. 2013;2(3):101-107. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3797882/

4. Sanches Abelan U, Savassa Pinto Cacoci RPh É, Elyan Azevedo Martins T, Mansanares Giacon V, Valéria Robles Velasco M, Rosana Ribeiro de Castro Lima C, et al. Potential use of essential oils in cosmetic and dermatological hair products: A review. J Cosmet Dermatol. 2021;00:1–12. Available from: https://pubmed.ncbi.nlm.nih.gov/34129742/ 

5. Chandorkar N, Tambe S, Amin P, Madankar C. A systematic and comprehensive review on current understanding of the pharmacological actions, molecular mechanisms, and clinical implications of the genus Eucalyptus. Phytomedicine Plus. 2021 Nov 1;1(4):100089. Available from: https://www.sciencedirect.com/science/article/pii/S2667031321000713#:~:text=It%20can%20be%20concluded%20that,the%20treatment%20of%20respiratory%20disorders

6. Wang X, Zheng J, Shen Y, Ma H, Xie D. Efficacy and safety of inhaled essential oil for postoperative nausea and vomiting: a systematic review and meta-analysis. Pharmacol Res Perspect. 2023;11(4):e01198. doi:10.1002/prp2.1198. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10322318/

7.  Eucalyptus Oil: Important information about eucalyptus oil [Internet]. Available from: https://www.medicines.org.uk/emc/files/pil.4843.pdf 

8. Gray AM, Flatt PR. Antihyperglycemic actions of Eucalyptus globulus (Eucalyptus) are associated with pancreatic and extra-pancreatic effects in mice. J Nutr. 1998 Dec;128(12):2319–2323. doi: 10.1093/jn/128.12.2319. Available from: https://academic.oup.com/jn/article-abstract/128/12/2319/4724260?redirectedFrom=fulltext

9. Sonker P, Verma S, Gupta P. To study the pharmacological effect and beneficial effect of Eucalyptus globulus in different types of diseases. Int J Res Pharmacol Pharmacother. 2017;6(1):81–88. doi:10.61096/ijrpp.v6.iss1.2017.81-88. Available from: https://www.researchgate.net/publication/320979770_81_To_Study_the_Pharmacological_Effect_and_Beneficial_Effect_of_Eucalyptus_Globulus_in_Different_types_of_Diseases

10. Sarkar S N. Capillary permeability-increasing effect of Eucalyptus hybrid leaf and Seseli indicum seed oils in rabbit. Indian J Pharmacol. 1994;26(1):55–56. Available from: https://journals.lww.com/iphr/abstract/1994/26010/capillary_permeability_increasing_effect_of.12.aspx

11. Maruyama N, Sekimoto Y, Ishibashi H, Inouye S, Oshima H, Yamaguchi H, et al. Suppression of neutrophil accumulation in mice by cutaneous application of geranium essential oil. J Inflamm (Lond). 2005;2:1. doi: 10.1186/1476-9255-2-1. Available from: https://journal-inflammation.biomedcentral.com/articles/10.1186/1476-9255-2-1

12. Kesharwani V, Gupta S, Kushwaha N, Kesharwani R, Patel DKM. A review on therapeutics application of eucalyptus oil. Int J Herb Med. 2018;6(6):110–115. Available from: https://www.researchgate.net/publication/332370890_A_review_on_therapeutics_application_of_eucalyptus_oil

13. WebMD. 12 Ways to Use Eucalyptus Oil [Internet]. WebMD; 2025 [cited 2025 Nov 17]. Available from: https://www.webmd.com/vitamins-and-supplements/ss/slideshow-eucalyptus-oil-benefits-and-uses

14. Moreira MR, Cruz GMP, Lopes MS, Albuquerque AAC, Leal-Cardoso JH. Effects of terpineol on the compound action potential of the rat sciatic nerve. Braz J Med Biol Res. 2001 Oct;34(10):1337-1340. doi:10.1590/s0100-879×2001001000015. Available from: https://pubmed.ncbi.nlm.nih.gov/11593310/

15. Kumar KJ, Sreenivasan T, Vinayak N, Sreenivasan U. Eucalyptus oil poisoning. Indian J Crit Care Med. 2015;19(6):376-378. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4721170/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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