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Covaxin vs Covishield – A Detailed Comparison – Efficacy, Side effects

Introduction

The COVID-19 vaccination drive has already begun in India and many people are still unaware of how the two vaccines – Covaxin and Covishield – are different from each other.

The third phase began on April 1, in which people over the age of 18 can take life-saving shots.

Currently, the government hasn’t allowed people to decide which vaccine they want to get, but the result of the first phase clearly suggests that both the vaccines being inoculated in India are safe and effective. As of now, 41.2 crore doses have been administered. 8.55 crore people of 6.3% of the total population are fully vaccinated.

Did you know?

Covaxin vs Covishield – Which One is Better?

Well, we have compiled all the information to give you a better understanding of the formulation and every other detail about covishield vs covaxin you are going to getto stay safe from the Coronavirus. Have a look:

1. Developer

Covaxin has been developed by Hyderabad-based Bharat Biotech International Ltd in association with the Indian Council of Medical Research (ICMR) and the National Institute of Virology (NIV). Covaxin is currently trying to procure WHO approval to ease international travelwoes for people who have opted for this vaccine. All the relevant documents have urgently been submitted to the officials of WHO. 

Because the Delta variant is proving to be more infectious than the other COVID variants, the makers of Covaxin have started a new study to determine the effectiveness of the third dose of Covaxin (the booster dose). The results are expected to be made public in November 2021.

Covishield has been developed by the Oxford-AstraZeneca and is being manufactured by the Serum Institute of India (SII). 

Doctors are mulling over the need for a booster dose for Covishield as well, considering the fact that the elderly and people with comorbidities may not be producing the desired immunity response to the Delta variant. 

2. Type of Vaccine

Covaxin is an inactivated viral vaccine. This vaccine is developed with Whole-Virion Inactivated Vero Cell-derived technology. They contain inactivated viruses, which can not infect a person but still can teach the immune system to prepare a defence mechanism against the active virus.

These conventional vaccines have been in use for decades now. There are vaccines for some other diseases as well which are made using the same technology. These diseases are:

If you are wondering Covishield is which type of vaccine, it has been prepared using the viral vector platform, a totally different technology.

A chimpanzee adenovirus – ChAdOx1 – has been modified to enable it to carry the COVID-19 spike protein into the cells of humans. Well, this cold virus is basically incapable of infecting the receiver but can very well teach the immune system to prepare a mechanism against such viruses.

The exact technology was used to prepare vaccines for viruses like Ebola.

3. Doses

There is no difference between the two vaccines in terms of dosage. Both of them are administered as 0.5ml in the upper arm region.

But, the dosing schedule for both vaccines however varies. The second dose of Covaxin is scheduled after 4-6 weeks after the first dose, while for Covishield vaccines it is 84 days or 12-16 weeks after the first dose.

4. Storage Guidelines

Both Covishield and Covaxin can be stored at 2-8 ° Centigrade, which is a household refrigerator temperature. This makes both the vaccines most suited for Indian conditions as most of the vaccines here are kept at the same temperature range. This also makes the transportation and storage of both vaccines easier.

5. Efficacy

Both vaccines have shown more than satisfactory results ever since the inoculation started in India.

The effectiveness of the Covishield vaccine is nearly 90% as per the global reports and the Covaxin vaccine’s is 81% according to interim 3rd phase trial results.

6. Side Effects

After getting vaccinated, you may experience pain at the site of injection. Some people may also experience side effects such as headaches, joint pain and may feel feverish. These side effects do not persist for long and generally go within a day or two.

7. Approvals

Covaxin has currently been granted approval for emergency restricted use, while Covishield has been allowed for restricted use in emergency situations that can potentially prevent coronavirus infection in people aged 18 years and above.

The Covaxin vaccine has begun its clinical trial in children aged above 2 years of age.

However, the Drugs Controller General of India (DGCI) has not given a market use authorization clearance to any of the vaccines till now.

8. Price of the Vaccines

Both the vaccines are being inoculated free of cost at government health set-ups. However, the cost of vaccines at the private hospital varies. Thus, you should always contact the hospitals for the exact cost of the vaccine.

9. Mode of Administration

Both Covaxin and Covishield are intramuscular vaccines.

10. Age of Beneficiaries

Covishield and Covaxin have been approved for people aged 18 years and above.

At PharmEasy, we wanted to extend our support to the Government of India in its COVID vaccination drive. And thus, with our ‘Go Corona Go Initiative’, we are offering a token of appreciation to every user who has got vaccinated. Basically, we’re on the lookout for SUPERHEROES who will help make India COVID-free. For every vaccine taken by a citizen, we would be giving a flat ₹150 PharmEasy cash in the wallet to the users that can be used on their next medicine order.

Summing up the Differences Between Covishield and Covaxin

Covishield

Covaxin

The Latest Updates on the COVID-19 Vaccine

Difference Between Sputnik V and the Other Two Vaccines

Sputnik V

Covishield and Covaxin

Also Read: What Are Intranasal Vaccines All About?

Click Here to Know More About Different COVID Vaccines

The Newest Vaccine to Arrive in India

In June, Drug Controller General of India gave Cipla the permission to procure the Moderna vaccine from the US. It is the first US vaccine to arrive in India. 7.5 million doses of the Moderna vaccine have been offered to India. 

This vaccine uses the mRNA technology and tests have found it to be 94.1% effective. 

Are you keeping a tab on your health? Let’s find out.

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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What Are Intranasal Vaccines All About?

Introduction

India has been vaccinating lakhs of people since March. Very soon, vaccines will be available for everyone above 18 years, irrespective of age groups or comorbidities. This brings us to hope at a time when COVID-19 has reared its ugly head again.

What comes as a piece of even more interesting news is that a new kind of medication may soon hit the markets. It’s called the intranasal vaccine for COVID-19.

So what is the intranasal COVID-19 vaccine, can it be trusted and should you opt for it? Let us answer all your questions.

What is the Intranasal COVID-19 Vaccine?

Intranasal vaccine for COVID-19 is a type of nasal spray/drop like the kind you use when you have a clogged nose. The formulation, of course, is different.

The nasal mucous is the first line of defence and hence very immuno efficient. Viruses have to breach this wall to enter your body and that is why this membrane is always on high alert. Studies have found that a small dose of antigen delivered into the nasal mucosa can trigger a rapid and powerful immune response. 

So, scientists have formulated the intranasal COVID vaccine. You have to pour a drop or spray into each nostril to help generate antibodies to fight the coronavirus.

What are the advantages of intranasal COVID spray?

First of all, it can be administered by the individual. Secondly, the intranasal vaccine is noninvasive and is not meant to be injected. Also, the intranasal vaccine can boost broad immune response. It is essential to stop both the infection as well as transmission of COVID-19. It is suitable and safe for children and eliminates the risk of needle-related infections and pain. Intranasal vaccines can also be produced in larger batches than other forms of COVID vaccines.

Also Read: Covaxin vs Covishield – A Detailed Comparison – Efficacy, Side effects

Are intranasal vaccines effective?

The intranasal vaccine can neutralize and generate a quick immune response at the mucosal membrane and stop the further spread of the virus. 

Until the intranasal vaccine is made available, continue to maintain all possible COVID precautions. Wear masks, sanitize your hands and try to maintain social distancing. If you are a senior citizen or have comorbidities, consider getting vaccinated as early as possible.  

Take a shot and stay fit.

Disclaimer: The information included at this site is for educational purposes only and is not intended to be a substitute for medical treatment by a healthcare professional. Because of unique individual needs, the reader should consult their physician to determine the appropriateness of the information for the reader’s situation.

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