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Licorice (Mulethi): Uses, Benefits, Side Effects, and More!

Introduction

Licorice, scientifically known as Glycyrrhiza glabra, is one of the most popular medicinal plants belonging to the Fabaceae family1. It is a perennial herb grown in temperate zones. The plant parts used are runners and roots, which are collected in the fall season. The medicinal use of licorice in western and eastern cultures dates back thousands of years, it is also one of the most common ingredients in Chinese medicine2. The name Glycyrrhiza is derived from the Greek terms ‘glykos’, meaning sweet, and ‘rhiza’, meaning root. It is native to the Mediterranean region and grown in India, China, Spain, Iran, Russia and Italy3. Licorice is also known as, Jothi-madh and Mulaithi (Hindi), Licorice, Liqourices, and Sweet wood (English), and Licorice, Liqourices, and Sweet wood (Sanskrit).

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Nutritional Value of Licorice

Licorice is the source of polysaccharides, simple sugars, proteins, amino acids, and mineral salts like calcium, sodium, potassium, iron, zinc, copper, phosphorous, magnesium, manganese, silicon, and selenium. It also contains vitamins like B1, B2, B3, B5, E and C. Pectins, starches, resins, and gums1.  

The chief constituent of the roots is glycyrrhizin, a triterpenoid saponins 50 times sweeter than sucrose1.

I have great news for those suffering from indigestion problems! A study6 found that the root extract of licorice might be a natural and effective remedy for indigestion. It may reduce symptoms, improves individual discomforts, and boosts quality of life.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Properties of Licorice

The properties of licorice are given as follows.

Potential Uses of Licorice

Due to its antibacterial and anti-inflammatory properties, there are many potential mulethi benefits and uses associated with licorice root extract4. Potential uses of licorice against some health conditions are given below.

1. Potential uses of licorice for cancer

cancer

The potential use of licorice in different cancers has been observed in lab-scale studies. However, more research is required to support the use of licorice against human cancer. Therefore, you are advised to strictly adhere to the doctor’s advice and treatment.

I would suggest licorice if you’re looking for a natural solution to keep your pearly whites healthy! It may have some incredible benefits for your oral and dental health. Yep, it’s true! Studies7 have shown that licorice and its powerful components are super effective against common oral problems such as cavities and gum diseases.

Dr. Rajeev Singh, BAMS

2. Potential uses of licorice for respiratory tract infection

respiratory disease

Oxidative stress and chronic inflammation are causes of chronic obstructive pulmonary disease. ISL has shown anti-inflammatory and antioxidant properties, due to which it was able to reduce the inflammatory cells in an animal study4. Licorice might be explored as a potential remedy for obstructive respiratory diseases. However, if you experience any respiratory problems, you must contact your healthcare provider immediately.

3. Potential uses of licorice for the liver

liver

Glycyrrhizin, found in licorice root has shown liver-protective potential in viral hepatitis. Japan and China have developed glycyrrhizin as a liver protective medicine. The anti-inflammatory and antiapoptotic properties of glycyrrhetinic acid, a compound found in licorice, may provide liver-protective benefits4. However, if you are suffering from liver problems, reach out to your healthcare provider immediately and get a proper diagnosis.

I came across a study8 that showed the protective effects of licorice extract in the kidneys of diabetic rats. It suggested that it may help improve blood glucose levels and reduce kidney damage. Although licorice extract may be a natural super-hero for diabetes and kidney health, its effects on humans still need to be investigated.

Dr. Smita Barode, B.A.M.S, M.S.

4. Potential uses of licorice against microbes

powdered licorice

Many laboratory studies4 suggest that licorice extract might be a potential agent against bacterial infection. During trials, licorice extract has shown promising results against Candida albicans and Staphylococcus aureus infections. However, infections require a medical diagnosis and treatment. If you experience any signs of infection, contact your healthcare provider before using licorice.

In my opinion, licorice root extract might just be your secret weapon against hot flashes. Licorice root extract shows promise for ladies going through menopause. It might act as a natural remedy for managing hot flashes9.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

5. Potential uses of licorice for inflammation

reduces inflammation

Inflammatory illnesses are becoming common and have a significant impact on daily life. Flavonoids found in licorice may be used as a potential medication for inflammation. Licorice extract has anti-inflammatory properties in managing various diseases, like acute kidney disease. ISL has shown anti-inflammatory activities in kidneys4. More research is needed to support the use of licorice in inflammatory conditions in humans. Therefore, talk to your healthcare provider and get a proper diagnosis.

6. Potential uses of licorice for skin

psoriasis

Though there are studies showing the benefits of licorice in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of licorice on human health. 

Also Read: Lemongrass: Uses, Benefits, Side Effects and More!

How to Use Licorice?

Roots and rhizomes of licorice can be used in the form of:

Your Ayurvedic physician will prescribe the form and dose as per your requirement.

You must consult a qualified doctor before taking licorice or any herbal supplements. Likewise, do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Also Read: Shilajit: Uses, Benefits & Side Effects

Side Effects of Licorice

Licorice is the word for mulethi in English. Potential mulethi side effects are shared below.

Before using licorice or any herbal remedy, you are advised to talk to your healthcare provider about the possible side effects associated with its use. It will help you avoid side effects.

Precautions to Take with Licorice

Here are some general precautions you need to take with licorice. 

Also, before using licorice for any health condition, you are advised to consult your doctor about the possible precautions associated with licorice.

Interaction with Other Drugs

Licorice root extract inhibits a major human drug-metabolising enzyme called the P450 enzyme. Therefore, it may increase the effects of drugs metabolised by the P450 enzyme2.

Also, if you are taking medicines for any health conditions, make sure you talk to your healthcare provider about the possible interactions of the drug with other herbs and medications.

Frequently Asked Questions (FAQs)

What is licorice?

The plant Glycyrrhiza glabra is commonly known as licorice. It belongs to the Fabaceae family. It is a medicinal plant3.

What is licorice called in Tamil?

Licorice is called Atimaduram in Tamil3.

Is it safe to consume licorice during pregnancy?

Licorice use should be avoided during pregnancy due to insufficient data available regarding its safe use5. Consult your healthcare provider before using any herbal remedy.

Is it safe to add licorice to food?

Licorice root is used as a flavouring agent for chewing gums, candies, baked goods, ice creams, and even soft drinks. The use of licorice extract and glycyrrhizin in foods has been approved by the United States Food and Drug Association, the Council of Europe, and the joint FAO/WHO Expert Committee on Food Additives1.

What are the benefits of licorice for skin?

Glycyrrhetinic acid may help manage eczema, contact and allergic dermatitis, and psoriasis. In addition, Glabrene and isoliquiritigenin found in licorice might be helpful in skin disorders like melasma and age spots that arise due to the accumulation of melanin. Glabrene and isoliquiritigenin may also be useful skin-lightening agents2.  However, before using any herb on your face or skin, you are advised to talk to your skin doctor.

How to use licorice for sore throat?

Licorice might be used as a demulcent for sore throat. Licorice powder, as well as extract, may be used for managing sore throat3. However, if your symptoms don’t improve, talk to your healthcare provider.

Can licorice be used as a sweetener?

Glycyrrhizin, the main constituent of licorice root, is 50 times sweeter than sucrose. Therefore, it can be used as a sweetener1.

References

1. Pastorino G, Cornara L, Soares S, Rodrigues F, Oliveira MBPP. Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. Phytotherapy Research [Internet]. 2018 Dec 1 [cited 2022 Mar 15];32(12):2323. Available from: https://pubmed.ncbi.nlm.nih.gov/30117204/

2. Murray MT. Glycyrrhiza glabra (Licorice). Textbook of Natural Medicine [Internet]. 2020 [cited 2022 Mar 15];641. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348626/

3. Sharma V, Katiyar A, Agrawal RC. Glycyrrhiza glabra: Chemistry and Pharmacological Activity. Sweeteners [Internet]. 2018 [cited 2022 Mar 15];87. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7124151/

4. Wahab S, Annadurai S, Abullais SS, Das G, Ahmad W, Ahmad MF, et al. Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology. Plants (Basel, Switzerland) [Internet]. 2021 Dec 1 [cited 2022 Mar 15];10(12). Available from: https://pubmed.ncbi.nlm.nih.gov/34961221/ 

5. Licorice Root – Health Encyclopedia – University of Rochester Medical Center [Internet]. [cited 2022 Mar 15]. Available from: https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=19&contentid=licorice

6. Raveendra KR, Jayachandra, Srinivasa V, Sushma KR, Allan JJ, Goudar KS, Shivaprasad HN, Venkateshwarlu K, Geetharani P, Sushma G, Agarwal A. An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study. Evid Based Complement Alternat Med. 2012;2012:216970. doi: 10.1155/2012/216970. Epub 2011 Jun 16. PMID: 21747893; PMCID: PMC3123991. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3123991/

7. Shaikh S, Kumar SM. Beneficial effects of specific natural substances on oral health. Saudi Med J. 2017 Dec;38(12):1181-1189. doi: 10.15537/smj.2017.12.20516. PMID: 29209665; PMCID: PMC5787627. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5787627/

8. Kataya HH, Hamza AA, Ramadan GA, Khasawneh MA. Effect of licorice extract on the complications of diabetes nephropathy in rats. Drug Chem Toxicol. 2011 Apr;34(2):101-8. doi: 10.3109/01480545.2010.510524. PMID: 21314459. Available from: https://pubmed.ncbi.nlm.nih.gov/21314459/

9. Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. Iran J Pharm Res. 2012 Spring;11(2):541-8. PMID: 24250477; PMCID: PMC3832176. Availlable from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3832176/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Sitopaladi Churna: Uses, Benefits, Side Effects & More!

Introduction

Sitopaladi churna is an Ayurvedic preparation used for digestive problems and various respiratory issues. Sitopaladi churna helps balance the kapha and pitta doshas. It is made from ingredients like cardamom (elaichi), cinnamon (twak), bamboo (vanshlochan), long pepper (pippali), and sugar candy (khandasharkara).

All these ingredients are cleaned and crushed to obtain a fine powder. The powder is then filtered to remove any coarse particles. Sitopaladi churna has a madhura (sweet) and katu rasa (bitter taste).   This churna may help to eliminate ama (harmful toxins) out of the body1

Ingredients of Sitopaladi Churna

The quantity of ingredients in sitopaladi churna is2

The inorganic elements present in sitopaladi churna are calcium, sodium, potassium, iron, magnesium, sulfate, phosphate, carbonate, nitrate, and chloride. The organic elements present in sitopaladi churna are carbohydrates, proteins, amino acids, steroids, flavonoids, alkaloids, tannins, and phenolic compounds2.  

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Properties of Sitopaladi Churna

The various beneficial properties of sitopaladi churna may include3

I would suggest sitopaladi churna in allergic disorders. There’s an important chemical called piperine found in the sitopaladi formulation. Owing to its capacity to stabilise mast cells, sitopaladi churna may be a justified treatment for allergic disorders13.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Sitopladi 

1. Potential Uses of Sitopaladi Churna for Cough

cough and cold

Sitopaladi churna contains expectorant properties that may help expel mucous from the airways. According to Ayurveda, cough is grouped into five categories: vata (dry cough that produces some mucous), pitta (cough that produces moderate and sticky mucous), ksataja (cough that occurs due to chest injury), and ksaya (cough that occurs due to tuberculosis-like chronic diseases).

Sitopaladi churna may be an helpful for all these types of coughs. It may be taken with honey, ghee, water, or other herbal medications. Sitopaladi churna may help with cough by acting on the central nervous system3. However these effects of sitopaladi churna may need further studies.

2. Potential Uses of Sitopaladi Churna for Digestive Health

Sitopaladi churna contains deepan (appetizing) and pachan (digestive) properties that may help to enhance digestion. It also contains carminative properties that might be helpful in gas accumulation and bloating3. The studies seem insufficient to validate these claims, therfore consult an ayurvedic physician before taking sitopaladi churna for its effect on digestion.

3. Potential Uses of Sitopaladi Churna for Allergies 

Allergy

The immune system in people with allergies responds to allergens like dust, pollen, dander, etc. by releasing a substance called histamine. Due to this, the person might experience symptoms like watery eyes or a running nose. Sitopaladi churna contains antihistaminic properties and might protect you from allergies4. You must visit a doctor immediately for relief in case of any allergic reactions.

4. Potential Uses of Sitopaladi Churna for Diabetes 

regulates blood sugar

The digestive enzyme amylase has to break down complex carbohydrates before they are absorbed. Carbohydrates are broken down into simple sugars and enter the blood leading to an increase in blood sugar levels. Sitopaladi churna may show α-amylase inhibition properties. This property might help prevent the body from absorbing these carbohydrates and prevents a spike in blood sugar after meals3. Diabetes is a major health condition and requires appropriate diagnosis and treatment from a professional doctor. Therefore, human trials of Sitopaladi churna are necessary to provide its potential usage for managing blood sugar levels in humans.

5. Potential Uses of Sitopaladi Churna for Anaemia 

stress

Anaemia can lead to shortness of breath, dizziness, tiredness, and irritability. The most common cause of anaemia is iron deficiency. Sitopaladi churna may help increase iron absorption by the body and thus helps in nutritional anaemia3. Further studies are needed to establish the claim of effect of sitopaladi churna for anaemia.

6. Potential Uses of Sitopaladi Churna for Migraine 

Migrane

Sitopaladi churna combined with other herbal medications, along with modified diet and lifestyle modifications like 8 hours of proper sleep, 30-60 min of morning or evening walk, and abstaining from smoking and drinking proved to be effective in the management of migraine5. However these claims need further studies, you must consult a doctor for proper advice on migraines.

7. Potential Uses of Sitopaladi Churna for Cough and Respiratory Problems

Respiratory

Sitopaladi churna may be helpful in conditions like fever related to flu, cold, chest congestion, pneumonia, tuberculosis, bronchitis, and other respiratory illnesses. This herbal preparation may help control respiratory infections due to its anti-inflammatory and antioxidant properties2. However, respiratory conditions may need medical supervision and diagnosis. Consult a qualified doctor for treatment of any respiratory condition.

8. Potential Uses of Sitopaladi Churna for Vocal Cord Nodules

voice and throat

Vocal nodules occur due to abuse or misuse of the vocal cords. Some professions require high-volume speech. This might lead to the formation of vocal nodules. Sitopaladi churna along with other herbal formulations may be used for managing vocal nodules. Studies show that it may give some relief from the symptoms and the person can regain their original voice6.  But consult a doctor for advice before consuming sitopaladi churna on your own.

Though there are studies showing the benefits of sitopaladi churna in various conditions, these are insufficient. There is a need for further studies to establish the true extent of the benefits of sitopaladi churna on human health. Furthermore, every person may respond differently to these herbs. Therefore, it is important to consult a doctor before using sitopaladi churna for any medical condition.

In my opinion, when we combine the herbal product from Bambusa arundinacea found in sitopaldi churna with other medicines, it might create a powerful anti-inflammatory drug. It’s like a dream team for treating chronic inflammatory conditions like rheumatoid arthritis with peptic ulcers, which are quite common. This combination may also offer hope for long-term treatment and relief in the said conditions14.

Dr. Rajeev Singh, BAMS

How to Take Sitopaladi Churna

Sitopaladi churna is available in two forms: 

Sitopaladi churna can either be taken with honey, water or ghee10. One should always take the advice of an Ayurvedic physician before having sitopaladi churna. In addition, we recommend you do not replace or discontinue your ongoing medications with any ayurvedic or herbal preparations without seeking the medical advice of a qualified doctor. They will guide you with the best form and dosage in which the herb can be used per your health condition.

Also Read: Avipattikar Churna: Uses, Benefits, Side Effects and More!

Side Effects of Sitopaladi Churna

There is not sufficient evidence for sideeffects of Sitopaladi churna and it may be safe when used by children and pregnant women. It is essential to consult an Ayurvedic physician and take only take prescribed doses3.

Also Read: Multani Mitti: Uses, Benefits, Side Effects & More!

Precautions to Take with Sitopaladi Churna

Also Read: Ragi (Finger Millet): Health Benefits and Tasty Recipes for Losing Weight

Frequently Asked Questions (FAQs)

Can sitopaladi churna be used for asthma? 

Due to its kapha and vata dosha balancing qualities, sitopaladi churna might be helpful in the management of asthma symptoms. It helps to breathe easily by clearing the air pathways7,8.  Every person may respond differently to these herbs. Therefore, it is important to consult a doctor before using sitopaladi churna for any medical condition.   

Can sitopaladi churna be used for intercostal neuralgia? 

Intercostal neuralgia is nerve pain right under you’re the ribs. There can be pain in the chest and upper back region. Sitopaladi churna may be helpful in the management of intercostal neuralgia9.  It is however, important to consult a doctor before using sitopaladi churna for any medical condition.   

How is sitopaladi churna prepared? 

The ingredients of sitopaladi churna are taken separately, crushed well to form a powder, and filtered through a clean cotton cloth. The ingredients are then mixed together to form a uniform mixture and then stored in an air-tight container10

Can sitopaladi churna be used in covid infections? 

According to a case report Sitopaladi churna might be helpful in post-covid lung complications due to its affinity towards the respiratory system11. This may be followed under supervision and guidance of a qualified doctor.

What are the other names of sitopaladi churna? 

Sitopaladi churna is also known by the names- sitopaladi choorna, sitopaladi choornam, sitopaladi chooran, etc12

Can Sitopaladi Churna be used for sore throat?

Yes, Sitopaladi Churna’s soothing properties can help ease the discomfort of a sore throat by reducing inflammation and providing relief from irritation. Mixing it with honey and consuming it may be beneficial for a sore throat.

How to take Sitopaladi Churna?

Sitopaladi Churna is typically taken orally with honey or warm water. The dosage and frequency may vary depending on the individual’s age, condition and the Ayurvedic practitioner’s recommendation.

Is Sitopaladi Churna suitable for individuals with diabetes?

Sitopaladi Churna contains sugar candy, which may impact blood sugar levels. Individuals with diabetes should consult their healthcare provider or an Ayurvedic practitioner before using it and consider alternatives without sugar candy.

Does Sitopaladi Churna have a pleasant taste?

Sitopaladi Churna generally has a pleasant taste due to the combination of sweet and aromatic herbs like sugar candy and cardamom. Mixing it with honey or warm water can enhance its taste.

Can Sitopaladi Churna be taken on an empty stomach?

Ayurvedic practitioners often recommend taking Sitopaladi Churna after meals for better absorption and to avoid any potential discomfort on an empty stomach.

References

  1. Planet Ayurveda. Sitopaladi churna. [Internet] Available from: https://www.planetayurveda.com/library/sitopaladi-churna/ 
  2. Dr. Anshuman Rajnala, Dr. RR Hiremath; Study of sitopaladi churna with reference to its physic-chemical, phytochemical and microbial analysis. Global journal for research analysis. 2017 Nov 6(11). Available from: https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/fileview/November_2017_1509787129__86.pdf 
  3. Jyoti Negi, Bharat Prashar, Jyoti Gupta; Sitopaladi churna as Anti-tussive: A review. International Journal of Health and Clinical Research. 2019 2(6): 1-5 Available from: https://www.ijhcr.com/index.php/ijhcr/article/download/43/37/117#:~:text=The%20percentage%20inhibition%20of%20bouts,%2C%20anti%2Dtussive%2C%20Review
  4. Bharti Ahirwar, Dheeraj Ahirwar, Alpana Ram; Antihistaminic effect of sitopaladi churna. Research journal of pharmacy and technology. 2008 1(2) Available from: https://rjptonline.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacy%20and%20Technology;PID=2008-1-2-19 
  5. Pub med. Response to Ayurvedic therapy in the management of migraine without era. [Internet] Available from: https://pubmed.ncbi.nlm.nih.gov/20532095/ 
  6. Rozina Ashrafali Khoja, Sarika M Makwana, DB Vanghela; A rare case report: Ayurvedic management of vocal cord nodules. International journal of health and allied sciences. 2019 8(4): 282-284 Available from: https://www.ijhas.in/article.asp?issn=2278-344X;year=2019;volume=8;issue=4;spage=282;epage=284;aulast=Khoja 
  7. Nikunj D patel, Prajesh N Prajapati, Niranjan S kanaki; Quality assessment of sitopaladi churna using high performance liquid chromatography coupled with multivariate analysis. Journal of chromatographic science. 2020 Nov-Dec 58(10): 961-968 Available from: https://academic.oup.com/chromsci/article/58/10/961/5917699 
  8. Central council for research in Ayurvedic sciences. Bronchial asthma. [Internet] Available from: http://www.ccras.nic.in/sites/default/files/viewpdf/faq/Bronchial%20Asthma%20article%20and%20FAQs%20for%20web%20site.pdf 
  9. National centre for biotechnology information. Physico-chemical standardization of sitopaladi churna. [Internet] Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530334/ 
  10. Kashimalai Nadaf, Mahantesh B. Rudrapuri, and G. Vinay Mohan; Development of sitopaladi khanda (granules) from sitopaladi churna and its analytical study. European journal of biomedical and pharmaceutical sciences. 2020 7(7): 503-506 Available from: https://storage.googleapis.com/journal-uploads/ejbps/article_issue/volume_7_september_issue_9/1601173224.pdf 
  11. Science direct. Ayurvedic evaluation and treatment of Covid 19: A case report. [Internet] Available from: https://www.sciencedirect.com/science/article/pii/S0975947621001364 
  12. Sai Chinmayee T, Geetha B. Markande, Subrahmanya Padyana; Pharmaceutico analytical study of sitopaladi choorna and its lehya. International Ayurvedic medical journal. 2020 May. Available from: http://www.iamj.in/prposts/2020/images/upload/02281_2284.pdf 
  13. Makhija IK, Shreedhara CS, Ram HN. Mast cell stabilization potential of Sitopaladi churna: An ayurvedic formulation. Pharmacognosy Res. 2013 Oct;5(4):306-8. doi: 10.4103/0974-8490.118824. PMID: 24174826; PMCID: PMC3807997. Available from:https://pmc.ncbi.nlm.nih.gov/articles/PMC3807997/
  14. Muniappan M, Sundararaj T. Antiinflammatory and antiulcer activities of Bambusa arundinacea. J Ethnopharmacol. 2003 Oct;88(2-3):161-7. doi: 10.1016/s0378-8741(03)00183-1. PMID: 12963137.Available from: https://pubmed.ncbi.nlm.nih.gov/12963137/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Babool (Acacia Nilotica): Uses, Benefits, Side Effects and More!

Introduction

Babool also called Acacia arabica, belongs to the family Leguminosae. Babool is a spiny, medium-sized, perennial tree commonly found throughout India1. The bark of the tree is known as Babur or Babul in Hindi. Today it is widely known as Gum Arabic as it was imported in large quantities in Arab. In India, babool is very commonly found in Maharashtra, Uttar Pradesh, Madhya Pradesh, Chhattisgarh, Jharkhand, Rajasthan and other dry regions of the country. Also, the thorny babool tree is seen in the neighboring Asian countries of Bangladesh, Sri Lanka, and Burma. It is native to North Africa and commonly seen in Egypt. It is more common in the western states of the peninsula. The vernacular names of babool are Babura, Kikar, Babula in Hindi Kaloabaval, Baval in Gujarati Babala, Babula in Oriya Babhula, Babhul in Marathi Babla in Bengali Babala in Assamese Indian gum Arabic tree, babula tree in English Kari Jail, Kari gobli, Sharmeeruka, Pulai Jali in Kannada Kikkar in Punjabi Sak in Kashmiri Thumma, Nallatumma in Telugu Karuvel, Karuvelan in Tamil Velutha Karuvelan in Malayalam Bavari, Kinkirata in Sanskrit1.

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Nutritional Value of Babool

The seeds of babool contain rich amounts of fiber and proteins. Its pods contain more fiber and have a lesser amount of protein as compared to the leaves3. There are many nutritional benefits of babool, including tannin, alkaloids, a polyphenolic compound, terpenoids, glycosides, and saponins2.

Properties of Babool

The  properties of babool include:

Recent studies suggest that the bark of Babool might be used as a natural dye for clothes. It is believed to bind dyes to the fabrics. This is fantastic news for those who love and enjoy wearing natural fabrics7.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Babool

Babool might have some potential uses in various conditions. However more studies are required. Some potential uses of babool are described as follows:

1. Potential Uses of Babool for Alzheimer’s Disease

brain

In a study, conducted by Crowch and Okello 2009 stated that babool had inhibitory activity on acetylcholinesterase enzyme. Acetylcholinesterase, an enzyme that breaks down the neurotransmitter acetylcholine, may be helpful in managing Alzheimer’s disease2. However, human studies are required to confirm its effectiveness on Alzheimer’s disease. Therefore it is essential first to consult a doctor and only use babool as a herb for Alzheimer’s.

2. Potential Uses of Babool for Malaria

mosquito

The water extract and ethyl acetate extract of babool was evaluated for antimalarial activity in an animal model by Malviya et al. 2011 and both exhibited antimalarial activity4. The extract of babool was found to have the highest anti-malarial activity against the malaria parasite Plasmodium falciparum. However, these studies are done on animals and not on humans. Therefore, we require more information on its safe usage on humans.

3. Potential Uses of Babool for Digestion

improve digestion

Babool may have shown anti-ulcer potential when tested on different animal models. The phenolic compounds present in babool might be responsible for the antiulcer activity2. In another study by Agunua et al. 2005, babool was tested for anti-diarrhoeal activity in animals. Initially, babool showed a relaxation effect followed by a contraction effect in the jejunum (middle part of the small intestine) of the animals. It also showed a 100% reduction from diarrhoeal infection in another animal model5. Therefore, it might indicate that babool may be beneficial for managing symptoms of diarrhoea. However, this research is insufficient as these studies are not done on humans. Hence, more studies on humans are required to suggest the potential use of babool for digestion. Therefore it is essential to first speak with your doctors and only use babool as a medicine.

4. Potential Uses of Babool for Diabetes

fpg, ppg & Hba1c numbers in diabetes

Studies have seen the blood glucose-lowering activity of babool extract, in an animal model studied2 by Kharya et al. 2010. The results showed that the babool extract might have a blood glucose-lowering effect. It exhibited a reduction in blood glucose, triglycerides, and cholesterol. This means it may help lower the risk of heart disease as well. Diabetes is a major health condition and requires appropriate diagnosis and treatment from a professional doctor. Therefore, human trials of babool are necessary to provide its potential usage for managing blood sugar levels in humans.

5. Potential Uses of Babool for Heart

heart

The antihypertensive activity of babool was tested in an animal model and humans (Gilani et al. 1999). The extract of babool was found to lower arterial blood pressure and give antihypertensive activity. In human studies2 conducted by Omaima et al. 2016, a drop in systolic and diastolic blood pressure was observed in participants with type 2 diabetes. This suggests that babool may be a potentially useful agent to lower blood pressure, especially in persons with diabetes5. However, these studies are insufficient and more new studies are required. Therefore, people should take advice from a doctor to stay updated about the latest benefits related to any herb.

6. Potential Uses of Babool as an Antioxidant

babool

A study2 by Kalaivani and Mathew 2010 reported that babool is a highly accessible source of natural antioxidants. It may be used in inflammation, cancer, and diabetes. The high antioxidant property of babool might be due to the phenolic compounds present in it. These antioxidants may fight the free radicals that are produced in the body. However, this information is insufficient and requires extensive research to support this claim.

7. Potential Uses of Babool for Cancer

cancer

The gum, flower, and leaf extract of babool were evaluated for anticancer activity in an animal model by Meena et al. 2006. Babool was found to affect tumor growth and showed a cytotoxic effect on cancer cells obtained from a human. In an animal study4, the use of babool was found to reduce tumor development. However, cancer is a serious health condition that might require proper treatment and diagnosis. So it is better first to have a consultation with a doctor. And more research is required to develop an accurate scope of babool for cancer-related problems in humans.

8. Potential Uses of Babool for Weight Management

weight management

Babool was investigated for its weight management activity in a human study by Omaima et al. 20165. A highly significant decrease in BMI (body mass index) was seen in prediabetic and diabetic groups, implying that babool might benefit weight management. However, this study is insufficient we require more human studies to provide the true extent of babool for weight management in humans.

9. Potential Uses of Babool for Infections

infection

A study2 conducted by Banso et al. 2009 was done to evaluate the antimicrobial activity of babool. The study showed that the bark extract might have antimicrobial activity against bacteria like Staphylococcus aureus, Streptococcus viridans, Escherichia coli, Shigella sonnei, and Bacillus subtillis. This study suggested that babool extract might be a potential antimicrobial agent. In another study by Kalaivani et al. 2010, babool showed the highest activity against 2 fungi strains (Aspergillus niger and Candida albicans) and 3 bacterial strains (Salmonella typhi, S. aureus, and E. coli). Babool may also be known for its antiviral activity against the virus Hepatitis C in infected liver cells. However, this information is insufficient because these studies are not done on humans and require more studies to be done on humans to support the use of babool for managing infections in humans.

10. Potential Uses of Babool on Galactogogue (increases milk production)

babool

In a study5 by Eline et al. 2004, the extract of babool was found to enhance the production of milk in rats and was shown to increase the production by 59% in an hour. However, human studies are required to confirm its activity on humans to stimulate higher milk production in nursing mothers. Therefore lactating mothers need to be aware of the safe usage of babool during these times. Also a doctor’s consultation is essential.

11. Potential Uses of Babool on Rectal Prolapse

babool

Prolapse means a displacement of an organ from its normal position. The decoction of babool bark may be used in rectal prolapse. The decoction of root bark may be used for stomach pain. The leave decoction is used in the form of nutool (a method of pouring the solution from a height over the specific part) in prolapse4. However, its effectiveness on humans requires more testing. However, more studies on humans are required to support the potential uses of babool for rectal prolapse. Therefore, a doctor’s advice is necessary.

12. Potential Uses of Babool on Mouth Ulcers

ulcer

The tender leaves of babool might be beneficial for treating mouth ulcers. It may be useful to clean the mouth, relieve pain, stop the bleeding of the gums, and might also help tighten the teeth5. However, its effectiveness requires confirmation via human studies. Therefore, people should consult their doctors and only use them to overcome the above-mentioned issue. Though there are studies showing the benefits of babool in various conditions, these are insufficient. And there is a need for further studies to establish the true extent of the benefits of babool on human health. Furthermore, every person may respond differently to these herbs. Therefore it is important to consult a doctor before using babool for any medical condition.

Spice up your life with your partner using Babool! Other than medicinal uses, Babool might be used as an aphrodisiac to enhance sexual life.

Dr. Rajeev Singh, BAMS

How to Use Babool?

Babool can be used as: 

One should always take the advice of an Ayurvedic physician before having babool. In addition, we recommend you do not replace or discontinue your ongoing medications with any ayurvedic or herbal preparations without seeking the medical advice of a qualified doctor. They will guide you with the best form and dosage in which the herb can be used per your health condition.

Did you know Babool might act as an expectorant as well? Researchers suggest that Babool might have the property to expel cough from the airways that might help to relieve the congestion.

Dr. Smita Barode, B.A.M.S, M.S.

Side Effects of Babool

Regular consumption of babool might have some side effects associated with stomach.

Precautions to Take with Babool

Having babool in moderation might be safe. However one must follow general precautions.

Also Read: Lemongrass: Uses, Benefits, Side Effects and More!

Interactions with Other Drugs

A review report (Ulbricht et al. 2008) suggested that babool was found to interact with amoxicillin (antibacterial medicine). It might affect the absorption of amoxicillin6. Therefore, avoid babool when you are taking amoxicillin. Thus, if you are taking antibacterial/antibiotic medicine, you must consult an Ayurvedic physician before consuming babool products. They will direct you to the better way to have it.

Frequently Asked Questions (FAQs)

What is babool in English called?

Babool in English is called an Indian gum Arabic tree1.

How to use babool?

Babool can be used as powder or decoction1. Small bark, juice of babool leaves, and tender leaves can be used. The powder form of flower, leaves, bark, pod, and wood may be used for leucorrhoea. Chewing babool bark and a decoction of the bark may be useful in cough. The paste or juice of babool leaves may be applied to lower the swelling and redness of the eye4. However, babool should not be used as self-medication. It is essential to take the doctor’s advice; they will recommend you the best form and dosage based on your health condition.

Is babool safe?

Babool is considered safe but has a few side effects. It might cause constipation and maybe harmful to the rectum, intestine, and chest5. Therefore, before using babool, please consult with your doctors.

Is babool good for teeth?

The small branches of babool may be beneficial for strengthening the teeth as they are used for brushing the teeth4. This fact is insufficient and requires a doctor’s advice to back this claim.

Can babool be taken during pregnancy?

There is not much data on its usage during pregnancy. Therefore, be on the safer side and avoid babool during pregnancy or consult your doctor before taking babool during pregnancy.

Is babool good for diabetes?

Babool was found to be beneficial for diabetes in various animal models2. However, its study in humans is not reported. Therefore, more studies on humans are required. Diabetes is a severe health problem that must be accurately diagnosed and treated by a qualified doctor.

Is babool good for cough?

Chewing of bark and decoction of babool might be helpful in relieving cough4. But we require more information to suggest the usage of babool for managing cough. People should not use it to self-medicate on their own prior to consulting a doctor.

Is babool good for mouth ulcers?

The tender leaves of babool might be helpful for mouth ulcers. It might also be used to clean  the mouth, relieve  pain, tighten  the teeth, and reduce gum bleeding4. However, this information is insufficient to say the potential benefit of babool for mouth ulcers. You can consult a doctor before using it.

Can I use babool during breastfeeding?

There is not much data on its safe usage during breastfeeding. Therefore, avoid babool during breastfeeding or consult your doctor before taking babool.

Is babool beneficial in malaria?

Babool was found to be beneficial for malaria in an animal model4. However, its effect on humans is still not studied. Therefore, more human trials are required to suggest the potential uses of babool in managing malarial infection.

Is there any interaction of babool with other drugs?

Babool was found to interact with amoxicillin, as suggested in the review report (Ulbricht et al. 2008). Therefore, avoid babool if you are taking amoxicillin6. However, if any harmful effect is observed, please get in touch with your doctors.

Is babool good for ulcers?

Babool was found to have anti-ulcer properties when tested in an animal model (Bansal et al. 2012)2. However its study in humans is still not reported. Therefore, we require more studies on humans to confirm the beneficial effect of babool for ulcers.

Is babool good for weight loss?

A human study5 (Omaima et al. 2016) found babool to lower the BMI (body mass index) of prediabetic and diabetic patients. Therefore, it might be helpful to lose weight. However, this information is insufficient and requires more studies to back this claim. We recommend you should consult a doctor before using babool for weight management.

References

  1. Health MOF, Welfare F. THE AYURVEDIC PHARMACOPOEIA Part-I [Internet]. 21–22 p. Available from: https://www.ayurveda.hu/api/API-Vol-1.pdf
  2. Zaman R, Shamsi S, Zaman R, Itrat M. Bark of Acacia Arabica -A Nature’s Gift: An Overview. Int Res J Med Sci [Internet]. 2014;2(5):20–4. Available from: https://www.researchgate.net/publication/332858395_Bark_of_Acacia_Arabica_-A_Nature’s_Gift_An_Overview
  3. Heuze V, Tran G, Eugene M, Bastianelli D, Lebas F. Babul (Acacia nilotica) [Internet]. Feedipedia, a programme by INRAE, CIRAD, AFZ and FAO. 2016. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9396638/
  4. Roqaiya M, Begum W, Jahufer R. Acacia arabica (Babool) – A Review on Ethnobotanical and Unani Traditional Uses as well as Phytochemical and Pharmacological Properties. J Pharm Phytopharm Res [Internet]. 2015;4(6):315–21. Available from: https://eijppr.com/storage/models/article/iKzp3TU9UBM4Qft8Zv8j96YD0xaT6F3YuIxKPFaFGtd0xjAn9q3ZVGl7nExU/acacia-arabica-babool-a-review-on-ethnobotanical-and-unani-traditional-uses-as-well-as-phytochemic.pdf
  5. Alam S, Anjum N, Akhtar J, Bashir F, Parveen S, Delhi N, et al. PHARMACOLOGICAL INVESTIGATIONS ON AQAQIA – Acacia arabica ( Lam .) Willd . 2018;6(1):3–6. Available at: https://ijcrt.org/papers/IJCRT1892006.pdf 
  6. Ulbricht C, Chao W, Costa D, Rusie-Seamon E, Weissner W, Woods J. Clinical Evidence of Herb-Drug Interactions: A Systematic Review by the Natural Standard Research Collaboration. Curr Drug Metab [Internet]. 2008 Dec 1;9(10):1063–120. Available from: http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1389-2002&volume=9&issue=10&spage=1063
  7. Rather LJ, Khan MA, Mohammad F. Biomordanting potential of Acacia nilotica (Babul) in conjunction with Kerria lacca and Rheum emodi natural dyes. Journal of Natural Fibers. 2019;16(2):275-286. doi:10.1080/15440478.2017.1414657. Available from: https://www.tandfonline.com/doi/abs/10.1080/15440478.2017.1414657

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Ashwagandha: Uses, Benefits & Side Effects

Introduction

Ashwagandha (Withania somnifera) is a popular herb in the Ayurvedic system of medicine. It is a small shrub that belongs to the Solanaceae family. It might be useful for different diseases and mostly as a nervine tonic (has a soothing effect on nerves). Ashwagandha is commonly called Indian Ginseng or Indian winter cherry. Ashwagandha is known for its rasayana (tonic) property. Rasayana is a herbal or metallic formulation that stimulates a youthful physical and mental state of health as well as happiness1.

Ashwagandha is cultivated in dry regions of South Asia, Africa, and Central Asia. More than 50 chemical constituents have been isolated from different parts of the ashwagandha plant1.

Did you know?

Nutritional Value of Ashwagandha

In 100 grams of ashwagandha, the nutrients found are:

Properties of Ashwagandha

The potential properties of ashwagandha are2:

Ashwagandha is also called an ‘adaptogenic’ herb or a ‘royal’ herb since it helps reduce stress and helps your body adapt to changes. It rejuvenates various body systems like the immune, reproductive and endocrine systems9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Potential Uses of Ashwagandha

The potential uses of ashwagandha for human health are as follows:

1. Ashwagandha for Anxiety and Depression

Ashwagandha might have anxiolytic (anxiety-relieving) properties that are similar to that of the drug lorazepam. Both ashwagandha and lorazepam showed to help reduce anxiety in animal models. Ashwagandha might also exhibit potential antidepressant properties. This indicates that Ashwagandha might help with depression and anxiety1. However, more research is required. Anxiety and depression may need serious attention and one should seek medical help from a professional for it.

2. Ashwagandha for Arthritis

Ashwagandha might have potential anti-arthritic properties that may be widely accepted and reported. Ashwagandha might help relieve pain by soothing the nervous system. In an experimental study6, patients were given a formula containing ashwagandha. This herbal formulation showed the potential to reduce the severity of pain and disability1,4. However, arthritis is a serious condition and must be diagnosed and treated by a doctor.

3. Ashwagandha for Cognition (Learning and Memory)

Ashwagandha is a popular Ayurvedic rasayana and belongs to medhyarasayanas, a subgroup of rasayanas. Medhya means mental/intellectual ability. Ashwagandha might help enhance memory and intelligence. This potential of ashwagandha for cognition was seen in children with compromised memory and old age as anecdotal evidence1. However, such claims lack scientific backup. Therefore, more research is required.

4. Ashwagandha for Stress

The circulatory system and cardiovascular health are adversely affected due to mental stress. Stress also affects the body’s antioxidant defence system7. Ashwagandha might help the body adapt to stress. It may also be effective in improving mental and physical health5. However, more research is required to ascertain such claims.

5. Ashwagandha for Pain

In a study8, treatment with an aqueous extract of ashwagandha showed potential to increase the pain threshold (a point beyond which a trigger produces pain) compared to that of placebo, showing that ashwagandha might be an analgesic agent. However, further research is required to state these as concrete facts.

Other Potential Uses of Ashwagandha

Ashwagandha might help deal with problems related to sleep and may contain sleep-inducing properties. It might also help one fall asleep faster and have an improved sleep quality7.

Though there are studies that show the potential uses of ashwagandha in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of ashwagandha on human health. 

Ashwagandha may be helpful in combating hair loss and promoting hair growth. Hair loss usually occurs due to stress. The lactones present in ashwagandha can reduce the levels of cortisol hormone in the body, which relieves stress10.

Dr. Anuja Bodhare, B.A.M.S, M.D (Ayu)

How to Use Ashwagandha

The important formulations of ashwagandha include:

It is also available in the form of tea, pills, gummies, or tincture. The roots, seeds, leaves, and flowers of ashwagandha can be used for medicinal purposes.

You must consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic/herbal preparation without consulting a qualified doctor.  

Did you know ashwagandha contains high levels of polyphenols, mainly catechin, which is responsible for its antioxidant actions? All the parts of ashwagandha, including the roots, leaves and fruits, are rich in catechin, which provides potential health benefits12.

Dr. Smita Barode, B.A.M.S, M.S.

Side Effects of Ashwagandha

The safety of the long-term use of ashwagandha has not been fully documented. However, the most common side effects of ashwagandha are:

The less common side effects are:

Also Read: Shilajit: Uses, Benefits & Side Effects By Dr. Anuja Bodhare

Ashwagandha might also cause liver damage. It is essential to call your healthcare provider when you experience any side effects, particularly those consistent with liver damage like itchy skin or jaundice7. Therefore, kindly consult an Ayurvedic physician before using ashwagandha. They will tailor the prescription according to your health needs.

Ashwagandha may be helpful in improving the performance of swimmers as it boosts stamina. It is possible that the duration that can be covered by swimmers taking ashwagandha is longer than those not taking it1.

Dr. Ashok Pal, B.A.M.S.

Precautions to Take with Ashwagandha

Ashwagandha must be avoided in some conditions like:

Kindly do not self-medicate, alter, replace, or discontinue any ongoing treatment. Please consult a doctor.

Ashwagandha is derived from two words: ashwa, meaning ‘horse’ and gandha, meaning ‘smell’. It is named so because the fresh roots of ashwagandha emit the smell of a horse. It is believed to boost vitality and strength in your body, comparable to a horse11.

Dr. Rajeev Singh, BAMS

Interactions With Other Drugs

It is essential to take precautions when using ashwagandha with:

To make sure that ashwagandha does not interfere with other medications, it is essential to consult your physician4.

Also Read: Arrowroot Powder: Uses, Benefits, Side Effects By Dr. Smita Barode

Frequently Asked Questions (FAQs)

What is ashwagandha?

Ashwagandha is a well-known herb used in Ayurvedic medicine. Its common names include winter cherry and Indian ginseng. It is obtained from a small evergreen shrub known as Withania somnifera. Ashwagandha might be helpful for a wide variety of ailments7.

Where is ashwagandha commonly cultivated?

In India, ashwagandha is cultivated in Uttar Pradesh, Gujarat, Rajasthan, Punjab and Madhya Pradesh4.

Can ashwagandha be used for the common cold?

The decoction of the roots of ashwagandha might be helpful for colds and chills. The root bark might be helpful for asthma4. Kindly do not self-medicate. Consult a doctor before taking ashwagandha for the common cold.

Can ashwagandha be used as an anti-inflammatory agent?

In Ayurvedic medicine, the root of ashwagandha is used as an anti-inflammatory agent by an Ayurvedic physician for dealing with tumours, swellings, scrofula (a type of tuberculosis), and rheumatoid arthritis (a condition affecting joints and bones)4. However, you are advised not to use ashwagandha for the above-mentioned conditions by yourself. Kindly consult an Ayurvedic physician for the same.

What are the indications of ashwagandha in Ayurvedic medicine?

Ashwagandha is indicated in conditions like syncope (temporary loss of consciousness associated with insufficient blood flow to the brain), piles, tumours, cervical lymphadenitis (enlargement of neck lymph nodes), gout (a type of arthritis), diseases of the skin, vitiligo (a disorder that causes the skin to lose color), lockjaw, heart failure, abscesses (a painful collection of pus), stiffness of the knee, cachexia (muscle and weight loss), bone fracture and diabetic carbuncle (cluster of painful boils)4. Kindly consult a doctor. Do not self-medicate.

What does ashwagandha do?


Ashwagandha, an adaptogenic herb, is known to reduce stress, boost immunity, improve cognitive function, and enhance overall vitality. Its active compounds may help regulate cortisol levels, promote relaxation, and support physical endurance, making it a popular choice in traditional medicine and wellness practices.

How much ashwagandha needs to be consumed per day?

The recommended dosage of ashwagandha typically ranges from 300 mg to 600 mg per day for most adults, divided into two or three doses. However, it’s crucial to consult with a healthcare professional to determine the appropriate dosage based on individual health factors and specific needs.

Can ashwagandha increase weight?

While ashwagandha is generally not associated with weight gain, some studies suggest it may support weight management by reducing stress-related overeating and regulating cortisol levels. However, individual responses may vary, and it’s advisable to consult with a healthcare provider before incorporating ashwagandha into a weight management regimen.

Can ashwagandha increase testosterone?

Ashwagandha has been studied for its potential to increase testosterone levels in men with low levels or infertility issues, attributed to its ability to reduce stress and improve overall hormonal balance. While research shows promising results, individual responses may vary, and consulting with a healthcare professional is advisable before using ashwagandha for this purpose.

References

  1. Narendra Singh, Mohit Bhalla, Prashanti de Jager, Marilena Gilca; An overview on ashwagandha: A rasayana (rejuvenator) of Ayurveda. African journal of traditional, complementary and alternative medicines. 2011 June 3 8(5): 208-213 Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/
  2. Kruthika Joshi, Swagata D Tavhare, Kalpesh Pandra, Praveen Kumar; Studies of Ashwagandha (withania Somifera Dunal). International journal of pharmaceutical and biological archives. 2016 7(1): 1-11. Available from: https://www.researchgate.net/publication/303343480_Studies_of_Ashwagandha_Withania_somnifera_Dunal/link/573dbb3908ae9ace84111bb9/download
  3. Swati Dongre, Deepak Langade, And Sauvik Bhattacharyya; Efficacy and safety of ashwagandha (withania somnifera) root extract in improving sexual function in women: A pilot study. BioMed Research International. 2015 Oct. Available from: https://www.hindawi.com/journals/bmri/2015/284154/
  4. Sleep foundation. Ashwagandha for sleep. [Internet] Available from: https://www.sleepfoundation.org/naturalsleepaids/ashwagandha#:~:text=unknown%20side%20effects.,Ashwagandha%20as%20a%20Sleep%20Aid,%25%20better14%2C%20on%20average
  5. The Ayurvedic Pharmacopoeia of India. Part-1 Volume-1. Available from: http://www.ayurveda.hu/api/API-Vol-1.pdf
  6. Ramakanth GS, Uday Kumar C, Kishan PV, Usharani P. A randomized, double blind, controlled study of efficacy and tolerability of Withaina somnifera extracts in knee joint pain. J Ayurveda Integr Med. 2016 Jul-Sep;7(3):151-157. doi: 10.1016/j.jaim.2016.05.003. Epub 2016 Sep 16. PMID: 27647541; PMCID: PMC5052364. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5052364/
  7. Office of Dietary Supplements (ODS), National Institutes of Health. Ashwagandha: Is it helpful for stress, anxiety, or sleep? [Internet]. Bethesda (MD): NIH; [updated 2 May 2025; cited YYYY Mon DD]. Available from: https://ods.od.nih.gov/factsheets/Ashwagandha-HealthProfessional/
  8. Bonilla DA, Moreno Y, Gho C, Petro JL, Odriozola-Martínez A, Kreider RB. Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis. J Funct Morphol Kinesiol. 2021 Feb 11;6(1):20. doi: 10.3390/jfmk6010020. PMID: 33670194; PMCID: PMC8006238. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8006238/
  9. Salve J, Pate S, Debnath K, Langade D. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus. 2019 Dec 25;11(12):e6466. doi: 10.7759/cureus.6466. PMID: 32021735; PMCID: PMC6979308. Available from: https://pubmed.ncbi.nlm.nih.gov/32021735/
  10. Ring C, Heitmiller K, Correia E, Gabriel Z, Saedi N. Nutraceuticals for Androgenetic Alopecia. J Clin Aesthet Dermatol. 2022 Mar;15(3):26-29. PMID: 35342503; PMCID: PMC8944288. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8944288/
  11. Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022. PMID: 23439798; PMCID: PMC3573577. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3573577/
  12. Alam N, Hossain M, Khalil MI, Moniruzzaman M, Sulaiman SA, Gan SH. High catechin concentrations detected in Withania somnifera (ashwagandha) by high performance liquid chromatography analysis. BMC Complement Alternat Med. 2011 Aug 19;11:65. doi:10.1186/1472‑6882‑11‑65. Available from: https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/1472-6882-11-65

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Swarna Bhasma (Gold Ash): Benefits, Side Effects & More!

Introduction

Metals have been used in Ayurveda and other Indian medical systems since ages, but they were also widely used in Chinese and Egyptian civilizations in 2500 B.C. Bhasma is an Ayurveda metallic mineral preparation prepared with herbal juice or decoction and then exposed for Ayurvedic purposes. A Bhasma is ash created by burning the original material goes through an extensive purification process, followed by the reaction phase, which involves the addition of various minerals and/or herbal extracts1. In general, the medicinal indications of Swarna/gold can be found in almost all ancient medical classics, such as the Charak Samhita (1500 BC), Sushruta Samhita (1000 BC), and Astang Hridaya (400 AD). Around the fourth century, the creation of Rasa Shastra began, and from then on, Swarna has been dealt with comprehensively in Rasa Shastra texts, with masterstrokes of its pharmaceutics and therapeutics. Swarna is the most outstanding of all metals, and it is classified as part of the Sara loha group, which means ”essence” or a noble metal. Tuberculosis, anemia, cough, debility, sterility, and muscular dystrophy have all been treated with the calcined form (Swarna Bhasma). Moreover, it is thought to be the best rejuvenator because it promotes longevity and prevents aging2

Ingredients of Swarna Bhasma

Uses of Swarna Bhasma

It demonstrates different therapeutic activities like: 

The tiny gold particles in Swarna Bhasma, measuring approximately 28-35 nm, have a unique ability to reach the affected areas when taken orally. This may allow for the continuous release of gold particles which is necessary for the desired beneficial effects4.

Dr. Rajeev Singh, BAMS

Benefits of Swarna Bhasma

1. Benefits of Swarna Bhasma as an Antioxidant

Antioxidant

Swarna Bhasma is a free radical scavenger, which means it consumes and removes free radicals from the body. Several proteins and enzymes in our body help to minimize the production of reactive oxygen species (O2, OH, H2 O2, and so on). After oxidative assault with acetic acid, two essential enzymes, superoxide dismutase (SOD) and catalase were assessed in two groups, Swarna Bhasma treated and control animals, blood or liver homogenate. Swarna Bhasma increased SOD activity (267 percent in serum SOD and 75.8 percent in liver homogenate, compared to the corresponding controls) and catalase activity (80 percent compared to control hemolysate). This could be linked to the patient’s improved pathophysiological status as well2. Via this free radical scavenging activity, it acts as an antioxidant and reduces inflammation.  

2. Benefits of Swarna Bhasma on the Nervous System

brain

Traditional gold preparations used in Ayurveda and Unani medicine had anxiolytic, anti-depressive, and anticataleptic properties with a large margin of safety. In a study2, treated animals showed a decrease in immobility time in the forced swimming test. They demonstrated a reduction in haloperidol-induced seizure scores.

3. Benefits of Swarna Bhasma for Pain

body pain and aches

The analgesic effects of Ayurvedic Swarna Bhasma, a calcined gold preparation, have been examined in various animal studies. Swarna bhasma was found to have analgesic efficacy in mice when tested using chemical, thermal, electrical, and mechanical methods. Swarna bhasma is thought to have opioid-like action which reduces pain2

Swarna Bhasma is traditionally regarded as a valuable formulation that may help manage insomnia and promote better sleep5.

Dr. Siddharth Gupta, B.A.M.S M.D (Ayu)

4. Benefits of Swarna Bhasma for Brain

brain

To assess brain damage due to poor blood supply and its alterations, various enzyme parameters were used. Ayurvedic Swarna Bhasma significantly restored altered values to near-normal levels. This implies that gold preparations may have potential in cerebrovascular disorders2.  

Experience the golden secret to a sharper mind and a resilient body with Swarna Bhasma! Studies state that by taking a small dose over time, this remarkable remedy might enhance memory and immunity7.

Dr. Smita Barode, B.A.M.S M.S.

How to Use Swarna Bhasma?

Gold has long been recognised for its antibacterial properties and its ability to modulate the immune system. However, when combined with honey and clarified butter, its effects may expand even further. This powerful combination might increase the scope of its effects to activate immune cells within the body7.

Dr. Anuja Bodhare, B.A.M.S M.D (Ayu)

Side Effects of Swarna Bhasma

Swarna Bhasma is believed to possibly enhance the potentiality. This traditional remedy may also contribute to a glowing complexion6.

Dr. Ashok Pal, BAMS

Precautions to Take with Swarna Bhasma

Also Read: Ashwagandharishta: Uses, Benefits, Side Effects & More!

Frequently Asked Questions (FAQs)

Can Swarna bhasma be used for arthritis?

In patients with rheumatoid arthritis, the effect of gold salt treatment has been investigated. When rheumatoid arthritis patients who were already receiving gold therapy were compared to those who had previously been treated or those who had never had this therapy, lower synovial fluid substance P levels (an inflammation related chemical) were seen, though not statistically significant2. Thus, use of Swarna bhasma in arthritis is not proven. 

Can Swarna bhasma be used for skin problems?

Use of Swarna bhasma suppressed production of a chemical called prostaglandin in vitro. In addition, in vitro, gold inhibited two human skin epidermis enzymes. These findings point to several potential mechanisms for gold’s impact in skin conditions like pemphigus with actions like disruption of the inflammatory cycle and inhibition of skin enzymes implicated in blister production2.

What are the common side effects of gold therapy? 

There are at least three types of gold-induced side effects: painful neuropathies i.e. nerve pain which are sometimes accompanied by sleeplessness and anxiety; peripheral neuropathy, i.e. damage to peripheral nerves of the limbs; and encephalopathy, including symptoms such as melancholy and psychosis2.

How is gold used in detection of cancer? 

Gold nanoparticles cling to cancer cells. They sparkle and are excellent at dispersing and absorbing light. This helps in quicker detection of cancer cells using gold. Epidermal Growth Factor (EGF) is a protein found in many cancer cells. They have Growth Factor Receptor (EGFR) all over their body. Usually, healthy cells do not usually express the protein in the same way2.

How does Swarna bhasma show immunomodulatory effects? 

Immunoglobulin-secreting cells are inhibited by gold. The activation of different complement pathways is inhibited by gold. Swarna bhasma inhibits numerous immune responses to antigens. The extent of gold’s immunoregulatory effects is unknown, and the relationship between these effects and its therapeutic properties is uncertain2.

References

  1. Pal, D., Sahu, C. K., & Haldar, A. (2014). Bhasma : The ancient Indian nanomedicine. Journal of advanced pharmaceutical technology & research, 5(1), 4–12. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3960793/
  2. Singh, N. & Chaudhary, Anand. (2012). Swarna Bhasma and gold compounds: An innovation of pharmaceutics for illumination of therapeutics. International Journal of Research in Ayurveda and Pharmacy. 3. 5-9.a. Available from: https://www.researchgate.net/publication/287178311_Swarna_Bhasma_and_gold_compounds_An_innovation_of_pharmaceutics_for_illumination_of_therapeutics
  3. Jamadagni, Pallavi & Jamadagni, Shrirang & Singh, Arjun & Singh, Rajendra & Upadhyay, Sachchidanand & Gaidhani, Sudesh & Hazra, Jayram. (2015). Toxicity Study of Swarna Bhasma,an Ayurvedic Medicine Containing Gold,in Wistar Rats. Toxicology International. 22. 11-17. 10.22506/ti/2015/v22/i3/137618. Available from: https://www.researchgate.net/publication/314174206_Toxicity_Study_of_Swarna_Bhasmaan_Ayurvedic_Medicine_Containing_Goldin_Wistar_Rats
  4. Paul W, Sharma CP. Blood compatibility studies of Swarna bhasma (gold bhasma), an Ayurvedic drug. Int J Ayurveda Res. 2011 Jan;2(1):14-22. doi: 10.4103/0974-7788.83183. PMID: 21897638; PMCID: PMC3157103. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3157103/
  5. Pal D, Sahu CK, Haldar A. Bhasma : The ancient Indian nanomedicine. J Adv Pharm Technol Res. 2014 Jan;5(1):4-12. doi: 10.4103/2231-4040.126980. PMID: 24696811; PMCID: PMC3960793. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3960793/
  6. Sarkar PK, Das S, Prajapati PK. Ancient concept of metal pharmacology based on Ayurvedic literature. Ancient Science of Life. 2010;29(4):1-6. Available from: https://pdfs.semanticscholar.org/4755/00243dc3212677fd7b3e1eaf66f4dbdf239d.pdf
  7. Nelaturi P, Nagarajan P, Sabapathy SK, Sambandam R. Swarna Bindu Prashana-an Ancient Approach to Improve the Infant’s Immunity. Biol Trace Elem Res. 2021 Jun;199(6):2145-2148. doi: 10.1007/s12011-020-02353-y. Epub 2020 Aug 27. PMID: 32856248; PMCID: PMC7451701. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7451701/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Hingwashtak Churna: Uses, Benefits, Side Effects & More!

Introduction

Hingwashtak Churna is a polyherbal Ayurvedic formulation sold in the form of powder. It is composed of eight main ingredients, namely Cuminum cyminum, Ferula foetida, Zingiber officinale, Piper nigrum, Piper longum, Nigella sativa, Trachyspermum ammi, and Saindhava Lavana (rock salt). The formulation is listed in the Ayurvedic Formulary of India and in Indian Herbal Pharmacopoeia. All the ingredients have a role to fulfil. Phytochemicals like alkaloids, glucosides, tannins, and phenols are present in Hingwashtak Churna1.

Did you know?

Ingredients of Hingwashtak Churna

Apart from phytochemicals, Hingwashtak Churna also contains nutrients like proteins and carbohydrates1.  

The composition of Hingwashtak Churna is depicted in the table below: 

Based on my experience, asafoetida contains essential oil with potential antioxidant properties and has been researched as a condiment that keeps cancer away. Hingvashtak Churna, which contains asafoetida may be used in the management of colon cancer5.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Uses of Hingwashtak Churna

The therapeutic uses of Hingwashak Churna are as follows: 

Benefits of Hingwashtak Churna

Hingwashtak Churna is used as a household remedy because of the many health benefits in dealing with problems associated with micturition (urination), defecation (passing stools), and flatulence (gas)1. The ingredients present in Hingwashtak Churna provide many health benefits, which are mentioned below.  

1. Benefits of Hingwashtak Churna in Relieving Flatulence

gastroesophageal reflux disease (gerd)

Piper nigrum and Piper longum have carminative activity. They help ease flatulence caused due to gases in the gastrointestinal tract. Asafoetida is also beneficial in getting rid of flatulence and distension of the abdomen1

2. Benefits of Hingwashtak Churna in Managing Painful Menstruation

In a case study, Hingwashtak Churna provided relief from abdominal pain caused due to primary dysmenorrhea. Primary dysmenorrhea is marked by painful menstruation without pathological abnormalities such as the septate uterus and uterine fibrosis. Hingwashtak Churna could also regulate the menstrual cycle. It does this by easing the menstrual flow2.  

3. Benefits of Hingwashtak Churna in Treating Indigestion

Hyperacidity

One of the ingredients found in Hingwashtak Churna, ginger powder, is beneficial in treating indigestion. It reduces the food retention time, facilitates greater secretion of bile acids, and also increases the efficacy of the digestive enzymes present in the stomach. Hingwashtak Churna helps in facilitating digestion and treating indigestion1.  

4. Benefits of Hingwashtak Churna in Managing Gastric Ulcers

Gastric Ulcers

Aqueous extract of Hingwashtak Churna was found to be effective in reducing the size of gastric ulcers. Many studies suggest the role of antioxidant activity of its ingredients for the benefits in managing gastric ulcers. Hingwashtak Churna is a promising candidate to be used as an adjunct to the existing peptic ulcer treatment3.  

In my experience, Hingvashtak Churna might be helpful in managing symptoms such as anorexia (loss of appetite). Its potential mechanism of action could involve improving digestion, reducing inflammation, and relieving discomfort in the gastrointestinal tract5.

Dr. Rajeev Singh, BAMS

How to Use Hingwashtak Churna?

The powder can be taken with ghee4. Your Ayurvedic doctor will prescribe you the dose based on your requirements.  

Also Read: Sitopaladi Churna: Uses, Benefits, Side Effects & More!

Precautions to Take with Hingwashtak Churna

You should keep the following points in mind: 

Also Read: Avipattikar Churna: Uses, Benefits, Side Effects and More!

Frequently Asked Questions (FAQs)

What is Hingwashtak Churna? 

Hingwashtak Churna is a polyherbal Ayurvedic formulation sold in the form of powder. It is composed of eight main ingredients, namely Cuminum cyminum (Cumin), Zingiber officinale (ginger), Ferula foetida (asafoetida), Piper longum (long pepper), Piper nigrum (black pepper), Trachyspermum ammi (ajwain), Nigella sativa (fennel), and Rock salt (Saindhava Lavana)1

What are the uses of Hingwashtak Churna? 

Hingwashtak Churna is a polyherbal formulation used as a digestive aid and to treat digestive disorders. It is also used as a household remedy to deal with the problems associated with defecation, micturition, and flatulence. It is a carminative and antispasmodic1.  

What are the health benefits of Hingwashtak Churna? 

The ingredients present in Hingwashtak Churna are responsible for many of its health benefits. It has benefits in managing gastric conditions like gas, indigestion, and peptic ulcers1,3. It is also beneficial in managing dysmenorrhea2

What are the benefits of Hingwashtak Churna in dysmenorrhea? 

Hingwashtak Churna could provide relief from abdominal pain caused due to dysmenorrhoea. Hingwashtak Churna could also regulate the menstrual cycle2. Irrespective of the benefits, Hingwashtak Churna should not be used to replace standard or conventional medicines. It can be used as an additional supporting aid and not as a stand-alone option. Consult a gynaecologist or a doctor for better advice on dysmenorrhoea.  

Is Hingwashtak Churna safe during pregnancy? 

There is no safety data about its use in pregnant and lactating women. Pregnant women are advised to take it under the guidance of an Ayurvedic physician.    

Can I take Hingwashtak Churna if I have a stomach ache? 

Hingwashtak Churna is beneficial in relieving the discomfort due to gas, acidity, and indigestion1. However, avoid self-medication. Consult an Ayurvedic physician or any medical practitioner for guided treatment options. The doctor will help you understand the cause of the problem before starting any treatment plan.  

Can I take Hingwashtak Churna to treat gastritis? 

Hingwashtak Churna cannot be used as a cure for gastritis. Though it is helpful in managing stomach-related problems like indigestion, gas and acidity, it should not be used as a treatment option for gastritis1. Consult a doctor for the treatment plans available for gastritis. Avoid self-medication as it might worsen the condition. Hingwashtak Churna can be used as a digestive aid but use it should be used after consulting with a doctor1

References

  1. Pal RS, Pal Y, Wal P, Wal A. In house & Marketed Preparation of Hingwashtak Churna, A Polyherbal Formulation: Comparative Standardization and Measures. Open Medicine Journal. 2018 Nov 1;5(1):76–83. Available from: https://www.semanticscholar.org/paper/In-house-%26-Marketed-Preparation-of-Hingwashtak-A-Pal-Pal/0459b545a2a70b254e6041d4cbac3fe818b6e1cd 
  2. Ajay Patil V, Hemantrao Zadbuke D, Pundalikrao Deshmukh S. AYURVEDIC MANAGEMENT OF DYSMENORRHOEA. World Journal of Pharmaceutical Research [Internet]. 2019;8:1200. Available from: https://wjpr.net/abstract_show/12474
  3. Shirwaikar A, Ram HNA, Mohapatra P. Antioxidant and antiulcer activity of aqueous extract of a polyherbal formulation. IJEB Vol44(06) [June 2006] [Internet]. 2006 [cited 2022 Feb 16];44:474–80. Available from: http://nopr.niscair.res.in/handle/123456789/6522 
  4. The ayurvedic formulary of India. Ayurvedic Pharmacopoeia Committee. Ministry of Health and Family Welfare. Government of India. 2000. Available from: https://books.google.com/books/about/The_Ayurvedic_Formulary_of_India.html?id=H6FFAAAAYAAJ 
  5. Dash M K, Joshi N, Dwivedi L, Sharma K. Probable mode of action of Hingvastaka Churna: a critical review. Int J Res Ayurveda Pharm. 2016;7(Suppl 3):1-8. PMID. Available from: https://ijrap.net/admin/php/uploads/1580_pdf.pdf

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Dashmularishta: Uses, Benefits, Side Effects & More!

Introduction

Dashmularishta is a widely used Ayurvedic tonic prepared using roots of ten different plants, thus the term ”dasha”, meaning ten. According to Sarngadhara Samhita1 (a well-known Ayurvedic textbook), Dashmularishta has the power to restore the body from an inflammatory condition to good health by rebuilding the tissues and revitalising the body. It is thought to be a wonderful tonic for women during the prenatal and peri-menopausal phases. We are going to discuss the various Dashmularishta uses and benefits in this blog.

Dashmularishta has been conferred with various therapeutic uses in Ayurvedic medicine due to the combined effect of the herbs. The herbs used are: 

Potential Uses of Dashmularishta

Dashmularishta is an ayurvedic tonic with a wealth of therapeutic benefits3. Some of the Dashmularishta traditional uses and properties are listed below: 

Benefits of Dashmularishta

1. Benefits of Dashmularishta for Osteoarthritis

Osteoarthritis is a common progressive condition of weight-bearing joints, mainly the hips and knee joints. Osteoarthritis is significantly seen in the older population, and it is regarded as the leading cause of disability among them. Dashmularishta is considered one of the best additions to osteoarthritis therapy and may help reduce the inflammation and pain caused by joint inflammation. In animal studies2, Dashmularishta was proven to significantly reduce swelling and improve the ability to take longer steps. 

2. Benefits of Dashmularishta for Pain Relief

Dashmularishta may help reduce the pain caused due to arthritis4. Oroxylum indicum, one of the primary ingredients of Dashmularishta, is well known for its pain-relieving property3. Animal studies2 indicate Dashmularishta benefits in osteoarthritis by potentially slowing the onset of stimuli that induce pain, preventing the pain itself. On further investigations, it may also prove effective in humans. 

3. Benefits of Dashmularishta for Heart

In Ayurveda, the herbal decoction called Dashmularishta is beneficial to manage heart diseases. Some ailments, like heart attack and stroke, are caused by the clotting of blood. Dashmularishta may act against the clotting property of platelets, which makes it an excellent agent to prevent blood clots and prevent heart attack and stroke. It may be used along with allopathic medicines for heart diseases5.  

In my opinion, Dashmularishta is the ultimate body superhero. This awesome tonic made from a blend of powerful herbs may work wonders for your body. It’s like a detox and nourishment combo all in one. It may help to remove toxins and might nourish your precious body tissues11.

Dr. Rajeev Singh, BAMS

4. Benefits of Dashmularishta for Allergic Conjunctivitis in Infants

In Ayurveda, Bala roga (Paediatric conditions) in breastfed babies are managed by examining both mothers and babies. It is believed that any irregularity in the mother’s diet or her physiology may manifest in the child as allergic conjunctivitis. Hence, the infant’s mother with allergic conjunctivitis is given Dashmularishta to manage the irregularities in appetite and bowel movements. The infant may be given appropriate remedies depending on the symptoms, and Dashmularishta is considered a safe remedy for nursing mothers as well6

5. Benefits of Dashmularishta in Women

For mothers who are breastfeeding, I would suggest trying Dashmularishta if you’re having trouble with your milk supply. This incredible tonic might work wonders in increasing milk production in women11.

Dr. Smita Barode, B.A.M.S M.S.

Also Read: Harad: Uses, Benefits, Side Effects, and More!

How to Use Dashmularishta

Dashmularishta is an ayurvedic tonic prescribed by the physician to be taken as directed. 

Your Ayurvedic physician will prescribe you the form and dosage as per your health condition.

I would recommend Dashmularishta if you’re looking to go the extra mile during physical exercises. In a study10, it was found that it might actually boost your swim endurance and help you fight off fatigue. Talk about an antifatigue superstar!

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Side Effects of Dashmularishta

 No adverse side effects have been documented due to the administration of Dashmularishta9.  

Also Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!

Conclusion

Dashmularishta truly stands out as a versatile herbal tonic with numerous benefits for the body and mind. Whether you’re looking to reduce inflammation, support women’s health, or boost your overall vitality, Dashmularishta offers a natural way to nourish and strengthen your body. Remember, while it has been used safely for centuries, it’s always best to check with an Ayurvedic doctor to get the right dosage and guidance tailored for you.

Also Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh

Frequently Asked Questions (FAQs)

Can Dashmularishta be used as a remedy for irregular periods? 

Yes, Dashmularishta might improve the hormonal imbalance in women and rectify the menstrual period. This can improve the period cycle to a significant extent and restore it to health.

How is Dashmularishta useful in men? 

There have been no documented benefits of Dashmularishta specifically for men. 

Is Dashmularishta used for weight loss therapy? 

There have been no documented benefits of Dashmularishta in weight loss. 

How is Dashmularishta useful in conceiving? 

Dashmularishta might improve ovarian function by rectifying the hormonal imbalance that prevents one from conceiving. PCOS is a major cause of infertility in women. Dashmularishta is an ayurvedic medication that is an excellent remedy for PCOS and other gynaecological disorders. Thus, Dashmularishta is found to help conceive women with gynaecological disorders by improving the hormonal levels and preventing any related metabolic disorders.

What is the dosage of Dashmularishta for arthritis?  

Please consult your Ayurvedic doctor for appropriate prescriptions and directions. Your doctor will prescribe you a specific dosage depending on your symptoms.  

What are the benefits of Dashmularishta for hair growth? 

No specific benefits of Dashmularishta have been documented for hair growth. 

What are the benefits of Dashmularishta for skin? 

No specific benefits of Dashmularishta have been documented for the skin.    

References

1. Pawar Nayana, Kogje Anushri, Bhondave Prashant, Nagarkar Bhagyashri, Kulkarni Omkar, Harsulkar Abhay, et al. Comparative free radical scavenging and anti-inflammatory potential of branded market samples of Ayurvedic formulations: Dashmoolarishta. International Journal of Pharma and Bio Sciences [Internet]. 2013 Jan [cited 2022 Mar 4];4(1):789–99. Available from: https://www.researchgate.net/publication/234877712_Comparative_free_radical_scavenging_and_anti-inflammatory_potential_of_branded_market_samples_of_Ayurvedic_formulations_Dashmoolarishta  

2. Shetty YC, Godbharle S, Brahma S, Salgaonkar S, Rege NN. Evaluation of oral multi-herbal preparation of Dashmoolarishta on mice model of osteoarthritis. J Basic Clin Physiol Pharmacol [Internet]. 2017 Jun 21 [cited 2022 Mar 4]; Available from: https://www.researchgate.net/profile/Yashashri-Shetty/publication/32044759

3. Ahad Amjid, Ganai Ajaz, Zeeshan Najm Mohammad. Therapeutic potential of Oroxylum indicum: A review. Journal of Pharmaceutical Research and Opinion [Internet]. 2012 [cited 2022 Mar 4];163–72. Available from: https://www.researchgate.net/publication/285800921_Therapeutic_potential_of_Oroxylum_indicum_A_review

4. Reshma R. Parekar, Kumar K. Dash, Aditi A. Apte, Nirmala N. Rege. EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF ROOT BARK OF CLERODENDRUM PHLOMIDIS IN EXPERIMENTAL MODELS OF INFLAMMATION. International Journal of Applied Biology and Pharmaceutical Technology [Internet]. 2012 [cited 2022 Mar 4];3(3). Available from: https://www.researchgate.net/publication/327931225_EVALUATION_OF_ANTI-INFLAMMATORY_ACTIVITY_OF_ROOT_BARK_OF_CLERODENDRUM_PHLOMIDIS_IN_EXPERIMENTAL_MODELS_OF_INFLAMMATION  

5. Parekar RR, Bolegave SS, Marathe PA, Rege NN. Experimental evaluation of analgesic, anti-inflammatory and anti-platelet potential of Dashamoola. Journal of Ayurveda and Integrative Medicine [Internet]. 2015 Jan 1 [cited 2022 Mar 4];6(1):11. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395922/

6. Shantala Priyadarshini, Teragundi Panaga, Gangadkar Pooja. Ayurveda Management of Allergic Conjunctivitis in 6 months old baby- A successful case study . International Journal of AYUSH Case Reports [Internet]. 2020 [cited 2022 Mar 4];4(2). Available from: https://ijacare.in/index.php/ijacare/article/view/145  

7. Nagarkar B, Mohite S, Kapoor E. EVALUATION OF EFFICACY OF DASHMOOLARISHTA IN CERVIVITIS: A PROOF-OF-CONCEPT STUDY. Article in Journal of Pharmacy and Pharmaceutical Sciences [Internet]. 2014 [cited 2022 Mar 4];3(6). Available from: https://www.researchgate.net/profile/Bhagyashri-Nagarkar/publication/264252846

8. Narayan Karandikar Ashwini. PCOS WITH INFERTILITY AND ITS AYURVEDA MANAGEMENT – A CASE STUDY [Internet]. International Journal of Ayurveda and Pharma Research. 2018 [cited 2022 Mar 4]. Available from: http://www.ijaprs.com/index.php/ijapr/article/view/1040  

9. Dwivedi M, Sastry JLN, Rai RK, Vedula S. Clinical Evaluation of Dashmularishta (Ayurvedic formulation) in Restoring Normal Health of Postpartum Females . Journal of research in  Traditional Medicine [Internet]. 2016 [cited 2022 Mar 7]; Available from: https://tmjournal.org/fulltext/140-1505301334.pdf?1646640147   

10. Gupta A, Madaan A, Srivastava R, Kumar S, Sastry JLN. Evaluation of antioxidant, immunostimulatory and antifatigue properties of Dashmularishta using in vitro and in vivo assays. Indian J Exp Biol. 2018 Aug;56(8):598–603. Available from: https://www.researchgate.net/publication/327269604_Evaluation_of_antioxidant_immunostimulatory_and_antifatigue_properties_of_Dashmularishta_using_in_vitro_and_in_vivo_assays

11. Jalwal NK, Pawan, BK. Formulation and evaluation of tablet of a classical fermented preparation of Dashmularishta. Int J Pharm Sci Res. 2015 Mar 31;6(3):123–8. Available from: https://www.semanticscholar.org/paper/Formulation-and-Evaluation-of-tablet-of-a-Classical-N.-Jalwal/8a2e9c631a4ea975f652d33cacee6aae32225318

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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Khadirarishta: Uses, Benefits, Side Effects & More!

Introduction

Khadirarishta is a polyherbal formulation used by people with rashes, itching, or sensitive skin. It is an ayurvedic liquid consisting of 18 ingredients. Also known as Khadirarishta, this preparation is used for treating skin problems, swollen lymph nodes, intestinal worms, leprosy, jaundice, and heart problems1,2. Khadirarishta consists of the ingredients Khadira, Devdaru, Bakuchi, Daruharidra, Haritaki, Bibhitaka, Amalaki, Dhataki, Kankola, Nagakeshar, Jatiphala, Lavanga, Ela, Tvak & Twakpatra, Pippali, honey, crystallised sugar lumps, and water.

Did you know?

  • Khadirarishta polyherbal may aid in the treatment of liver disorders like fatty liver disease. source: ncbi
  • Khadirarishta polyherbal may aid in the treatment of urinary stones. source: ncbi
  • Khadirarishta polyherbal may help in managing respiratory conditions like asthma and bronchitis. source: ncbi
  • Khadirarishta, an herbal fermented liquid, is recommended for all types of skin diseases, including psoriasis. source: J Ayurveda Integr Med
  • Khadirarishta polyherbal may help in managing diabetes by regulating blood sugar levels. source: NCBI

Uses of Khadirarishta

Khadirarishta has the following therapeutic uses: 

Benefits of Khadirarishta

1. Benefits of Khadirarishta for Bacterial Infection

Allergy

Khadirarishta contains a broad antibacterial range that includes bactericidal action against E. coli, S. aureus, and S. enterica. Khadirarishta’s method of action appears to be tied to bacterial membrane permeability disruption. Gallic acid, catechin, ellagic acid, and eugenol found in khadirarishta were identified as the four primary marker chemicals3.

2. Benefits of Khadirarishta for Fungal Infection

infection

A phenolic compound bakuchiol in Khadirarishta extracted from Bakuchi (seeds) and haritaki exhibited antifungal activity against many dermatophytes, yeasts and pathogenic fungi like Trichophyton rubrum and Microsporum gypseum, Epidermophyton floccosum, and Trichophyton mentagrophytes. In one of the studies, activity was found against other fungi such as Aspergillus niger, Alternari brassicae, Fusarium oxysporum, and Rhizoctonia cerealis, in which mycelia (the vegetative part of a fungus) growth was inhibited.  

Another study4,5 showed a significant reduction in the incidents of seed”borne fungi, for example, Fusarium verticillioides and Aspergillus flavus, which can cause many diseases in maize crops and might release mycotoxins. These mycotoxins have a terrible effect on human and animal health.

3. Benefits of Khadirarishta for Skin

skin

Haritaki reduces pus collection in skin ailments and serves as a Rasayana, making it useful for erysipelas. Haritaki found in khadirarishta combined with oil aids in the healing of wounds, particularly burns. It aids in the improvement of skin tone5.

Daruharidra, and Bibhitaka present in khadirarishta also possess wound healing properties. They have anti-inflammatory and antioxidant activities which promote the health of the skin6,7.  

Did you know that the ancient text ‘Sharangdhara Samhita’ holds a treasure trove of information about Khadirarishta? This traditional Ayurvedic text provides detailed insights into the ingredients used, the method of preparation, therapeutic indications, and even the mode of action of Khadirarishta9.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

4. Benefits of Khadirarishta for Respiratory Diseases

respiratory disease

Haritaki present in khadirarishta shows activity against respiratory disorders like COPD, wheezing, rhinitis, hoarseness of voice, cough, hiccups and breathing difficulty as it reduces congestion in the lungs5.

5. Benefits of Khadirarishta for Reproductive health

Haritaki present in khadirarishta acts as a uterine tonic and helps in Shukrameha (passage of sperms in urine), and Leucorrhoea (whitish/yellowish vaginal discharge)5.

6. Benefits of Khadirarishta for Cancer

cancer

The stem of Daruharidra found in khadirarishta shows anticancer properties in human colon cancer cell lines when extracted in methanol. Methanolic extract of Daruharidra stem inhibits cancer-causing cells in a concentration-dependent manner. Berberine, an alkaloid derived from the Daruharidra plant, has been reported to suppress the carcinogenesis produced by different elements in small animals in a dose-dependent way7.

Khadirarishta, a traditional herbal preparation, contains an important ingredient called Khadira. It is a special herb that might help with various health issues from conjunctivitis and coughing up blood to nausea and diarrhoea10.

Dr. Smita Barode, B.A.M.S, M.S.

How to Use Khadirarishta?

You can use Khadirarishta by mixing a fixed amount of the liquid with lukewarm water1

One of the key ingredients in Khadirarishta is Daruharidra, which has some remarkable properties! This special herb is known to possibly provide a rejuvenating effect, making you feel refreshed and revitalised10.

Dr. Rajeev Singh, BAMS

Side Effects of Khadirarishta

Also Read: Neem: Uses, Benefits, Side Effects, and More!

Precautions to Take with Khadirarishta

Please consult a physician before using in pregnant and lactating women and in children.  

Frequently Asked Questions (FAQs)

What is Khadirarishta? 

Khadirarishta is an ayurvedic formulation consisting of 18 ingredients like Khadira, Devdaru, Bakuchi, Daruharidra, Haritaki, Bibhitaka, Amalaki, Dhataki, Kankola, Nagakeshar, Jatiphala, Lavanga, Ela, Tvak & Twakpatra, Pippali, honey, crystallised sugar lumps and water.  

Does Khadirarishta cause any side effects? 

When used as directed by your doctor, Khadirarishta normally has no side effects. This multi-herbal ayurvedic composition, however, can create a burning sensation or heartburn if ingested without water1. An overdose of this formulation could harm your heart, kidneys or liver2.

How does Khadirarishta help to cure dental problems?

No, khadirarishta is not known to show any activity for dental problems.

Does Khadirarishta causes inflammation? 

No, khadirarishta does not cause inflammation. It has various herbs that have anti-inflammatory properties and may help in reducing inflammation. 

Does Khadirarishta increase blood haemoglobin levels? 

Khadirarishta helps in increasing the haemoglobin of the blood and hence helps in the treatment of anaemia8.

How to take Khadirarishta formulation? 

Khadirarishta should be mixed with water before consumption. The dose of this ayurvedic formulation should be as prescribed by your doctor. 

Can khadirarishta be used for eczema? 

When khadirarishta was consumed with lukewarm water after meals for a few months, it showed improvement in the symptoms of eczema like itching, skin discolouration and secretions8.

What are some of the benefits of amalaki? 

Antidiabetic and hypoglycemic properties: Emblica fruit powder lowered blood sugar levels in normal and hyperglycemic rabbits, demonstrating hypoglycemic efficacy. 
Anti-peptic ulcer activity: With traditional antacids and Emblica fruits, 30 instances of ulcer and non-ulcer dyspepsia showed equivalent improvement8

References

1. Shinde RR, Bhangale K. KHADIRARISHTA: A MEDICAL REVIEW. International Journal of Research -GRANTHAALAYAH [Internet]. 2017 Oct 31 [cited 2022 Feb 28];5(10):72–5. Available from: https://www.granthaalayahpublication.org/journals/index.php/granthaalayah/article/view/IJRG17_A10_712/2158 

2. Sharif T, Deepa KN, Nahar K, Mian Y. Evaluation of cardiovascular activities of an ayurvedic preparation ”Khadirarishta” in rat model. European Journal of Pharmaceutical and Medical Research. 2015;(January). Available from: https://www.researchgate.net/publication/282322014_EVALUATION_OF_CARDIOVASCULAR_ACTIVITIES_OF_AN_AYURVEDIC_PREPARATION_’KHADIRARISHTA’_IN_RAT_MODEL

3. Balkrishna A, Gupta AK, Gupta A, Singh P, Singh K, Tomar M, et al. Antibacterial activity and mechanism of action of an ayurvedic formulation Khadirarishta. Journal of Herbal Medicine. 2022 Mar 1;32.  Available from: https://www.researchgate.net/publication/354148224_Antibacterial_Activity_and_Mechanism_of_Action_of_an_Ayurvedic_formulation_Khadirarishta

4. Alam F, Khan GN, Asad MHH bin. Psoralea corylifolia L: Ethnobotanical, biological, and chemical aspects: A review. Vol. 32, Phytotherapy Research. John Wiley and Sons Ltd; 2018. p. 597–615.  Available from: https://pubmed.ncbi.nlm.nih.gov/29243333/

5. Meher SK, Panda P, Das B, Bhuyan GC, Rath KK. Pharmacological Profile of Terminalia chebula Retz. and Willd. (Haritaki) in Ayurveda with Evidences . Research Journal of Pharmacology and Pharmacodynamics. 2018;10(3):115. Available from: https://www.researchgate.net/publication/327831052_Pharmacological_Profile_of_Terminalia_chebula_Retz_and_Willd_Haritaki_in_Ayurveda_with_Evidences

6. Ashutosh Gupta RKK and AKP. Pharmacological Aspects of Terminalia belerica. 284 p. Available from: https://www.researchgate.net/publication/321193582_Pharmacological_Aspects_of_Terminalia_belerica

7. Kumar Saini Jubilant Biosys N. Berberis aristata: A Review [Internet]. Article in International Journal of Research in Ayurveda and Pharmacy. 2011. Available from: www.ijrap.net 

8. Parulkar G. KHADIRARISHTA: A MEDICO STUDY. Parulkar World Journal of Pharmaceutical Research [Internet]. 2016 [cited 2022 Feb 28];5(11). Available from: www.wjpr.net 

9. Parulkar G. KHADIRARISHTA: A medico study. World Journal of Pharmaceutical Research. 2016;5(11):568-72. DOI:10.20959/ Available from: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1477907087.pdf

10. Shinde RR, Bhangale K. KHADIRARISHTA: A MEDICAL REVIEW. International Journal of Research – GRANTHAALAYAH. 2017 Oct 31;5(10):72-75. doi:10.29121/. Available from: https://www.granthaalayahpublication.org/journals/index.php/granthaalayah/article/view/IJRG17_A10_712/2158

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

  

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Hadjod (Cissus Quadrangularis): Uses, Benefits, Side Effects & More!

Introduction

Cissus quadrangularis, commonly known as ‘Hadjod’ in Hindi, is a fleshy plant belonging to the Vitaceae family1. It is known by numerous vernacular names depending on the region. In Bangladesh, it is known as Hathisur in Sri Lanka, it is known as Heeressa in West Africa, it is known as Treebine, Zarnazaru, Banddiagra, Oongoonujaara in Thailand, it is known as Khankho, phet sangkhaat, san cha khuat and in India, it is known as Bonesetter, Adamant creeper, Veldt-grape, Hadjod, Hadsanka and Asthisamadhani. Hadjod, also known as Asthisamharaka, is a luscious herb found in India’s warmest regions. It can grow up to 500 meters above sea level in plain coastal areas, forests, and wastelands. Stem cuttings are used to propagate the herb. From June to December, the herb blooms. It is a climbing herb that turns leafless as it ages. It is a shrubby climber that can grow up to 1.5 meters tall. The plant blossoms small greenish-white flowers. The leaves are 2.5-5 cm long, broadly ovate or kidney-shaped leaves. The calyx is cup-shaped, short, and deciduous. There are 4-5 petals on each flower. The fruits are obovoid, very acrid, one-seeded, and dark purple to black. The stem is smooth, branched, glabrous, subangular, and fibrous and found to be buff colored with a greenish tinge. The stems measure 8–10 cm in length and 1–1.5 cm in width2. Iridoids, alkaloids, flavonoids, stilbene derivatives, sterols, triterpenes, fatty acids, methyl esters, and other phytochemicals have been found in the hadjod. The presence of five well-known chemicals on leaves was discovered, including Tetratriacotanol, Ecosyl eicosanoate, Tetratriacontanoic acid, α,β-amyrin, β-sitosterol. Polyphenols such as Daidezein, Quercetin, and Genistein were also reported in the leaves1

Nutritional Value of Hadjod

The nutritional content fount in hadjod root powder/100 gm is: 

Uses of Hadjod

Hadjod might be your ally in dental problems! Yes, you read it right Recent studies have revealed that the use of Hadjod may help in alleviating dental cavities when they start due to its anti-bacterial nature5.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Benefits of Hadjod

1. Benefits of Hadjod for Pain

osteoarthritis

Traditional Hadjod folklore is that it is used to relieve pain. Animal models that are widely accepted worldwide were used to test its analgesic potential. Hadjod’s effects were shown to be effective even at low doses, indicating that the herb has high potency in simulating central and peripheral pain. The phytosterols β-sitosterol and β-sitosterol glycoside, terpenoids, and phenolic substances such as resveratrol, quercetin, quercitrin, and kaempferol found in hadjod are thought to have analgesic properties2.

2. Benefits of Hadjod for Ulcer

Gastric Ulcers

The presence of phytochemicals like polyphenols, glycosides, vitamin C, and β-sitosterol in hadjod may contribute to antiulcer potential or accelerate ulcer healing by releasing polyamines and transforming growth factor-α. Hadjod displayed cytoprotection by increasing potassium, hexosamine, bicarbonate, and the carbohydrate, protein ratio while lowering pepsin, proteins, and acid secretion in the stomach2.

3. Benefits of Hadjod for Infections

skin infections

Traditional literature mentions the use of hadjod in treating a variety of bacterial and viral infections. The steroids and flavonoids present in a partially purified extract of the hadjod stem were found to have excellent antiviral activity against herpes simplex virus types I and II2. In an antibacterial study, six different extracts of hadjod stem were tested against gram-positive and gram-negative bacteria. As a result, methanol extract was found to have superior antibacterial activity against S. pyogenes, B. subtilis, S. aureus, P. aeruginosa, and S. typhi, among other bacteria2. The antifungal activity of hadjod extract was determined by comparing it to the standard medication fluconazole. The diameter of the zone of inhibition generated on the surface of Petri dishes was used to determine antifungal activity. The study found that hadjod extract had promising antifungal efficacy against Aspergillus flavus1

4. Benefits of Hadjod for Worm Infections

hadjod

On the Haemonchus contortus worm, the anthelmintic activity of hadjod extract was investigated. The presence of alkaloids, flavonoids, tannins, and phenols in the extract may contribute to its anthelmintic effect2

5. Benefits of Hadjod for Cancer

cancer

Hadjod has shown anticancer and antitumor activity in a variety of cancer cell lines, including breast cancer, osteosarcoma, leukaemia, Dalton’s ascitic lymphoma, and Erlich ascitic-induced carcinoma. The extract of hadjod at various doses has been investigated to protect rats from breast cancer. All biochemical and haematological changes caused by 7,12-Dimethylben (a) anthracene were reversed when rats were given hadjod extract2

6. Benefits of Hadjod for Inflammation

reduces inflammation

Ear oedema was used to test hadjod’s anti-inflammatory activity in rats. Hadjod can reduce swelling, relieve pain, treat allied illnesses associated with fractures, and aid in healing fractures. The inclusion of Beta-sitosterol and luteolin flavonoids in hadjod is responsible for its anti-inflammatory properties. Hadjod inhibits many inflammatory mediators that increase vascular permeability, support vasodilation, and cause oedema development3

7. Benefits of Hadjod for Obesity

In hyperlipidemia models in rats, hadjod extract significantly reduced the total cholesterol, triglycerides, low-density lipoprotein cholesterol, and atherogenic index while increasing high-density lipoprotein cholesterol levels. Hadjod’s antihyperlipidemic properties are thought to be related to phytosterols, including stigmasterol, β-sitosterol, ketosteroid, and flavonoids like kaemferol, quercetin, and daidzein. Phytosterols may lower low-density lipoprotein cholesterol levels or diminish intestinal cholesterol absorption by increasing faecal cholesterol excretion2

8. Benefits of Hadjod for Fertility

fertility

In rats, an extract of hadjod stem restored significant abnormalities caused by lead acetate. The use of hadjod extract on rats increases total sperm count. Antioxidant deficiency harms sperm viability and motility in males. Hadjod’s anti-infertility effect is attributed to its antioxidant enzymes restorative capacity or pregnancy abruption, implantation inhibition, and abortion induction2

9. Benefits of Hadjod for Diabetes

fpg, ppg & Hba1c numbers in diabetes

In diabetic rats, the injection of hadjod extract at various doses considerably lowers blood glucose levels. Furthermore, hadjod extract caused a rise in plasma insulin levels and restored liver antioxidant enzymes and histology in diabetic mice. Improvements in glycemic metabolism and regulation, free radical elimination, cholesterol reduction, insulin secretion, and microcirculation can contribute to hadjod’s antidiabetic action2

10. Benefits of Hadjod for Haemorrhoids

Haemorrhoids

Hadjod extract’s anti-hemorrhoids activity was tested on an isolated human umbilical vein, which caused contraction of vascular smooth muscles of the vein. Hadjod extract was found to have a vasoconstrictive impact on the intact inner lining of the vein2. In clinical research, taking a tablet of hadjod reduced piles symptoms in patients. Flavonoids, which are significant phytochemicals, are thought to help treat haemorrhoidal diseases by reducing localized bleeding, itching, and discomfort, potentially by improving capillary resistance and venous tonicity by lowering capillary permeability2

11. Benefits of Hadjod for Immunomodulation

blood toxicity

Hadjod’s extract significantly increased blood carbon clearance, blood immunoglobulin levels, and a delayed type of hypersensitive response to sheep red blood cells. In another study, hadjod extract nanoparticles corrected immunosuppression in immunosuppressive animals using sheep red blood cells. The findings suggested that hadjod had immunomodulatory properties in both cellular and humoral immunity.

12. Benefits of Hadjod for Arthritis

Arthritis

Hadjod has been shown to have antiarthritic potential in various animal models. Hadjod extract was found to have an antiarthritic effect by reducing bone and cartilage degeneration, excessive paw inflammation, and associated biochemical and haematological changes2

13. Benefits of Hadjod for Bone Function

Hadjod’s antiosteoporotic potential has been demonstrated in various animal models by several authors. An osteoporotic rat model of ovariectomy, closed fracture by bending the radius-ulna in rats and dogs was used to test the antiarthritic activity of hadjod extract. The work was carried out in vitro using cell lines. Few clinical studies have shown that hadjod, combined with Zingiber officinale, can reduce joint swelling, discomfort, and soreness in osteoporotic and fractured patients. Hadjod’s bone protective activity is thought to be due to its steroidal content, which functions as phytoestrogens to prevent or minimise bone loss and suppress bone reabsorption caused by oestrogen deficiency2

14. Benefits of Hadjod as an Antioxidant Activity

hadjod

Various research has already assessed the antioxidant activity of hadjod utilizing different antioxidant assays and procedures. By lowering serum enzyme levels and boosting antioxidant enzyme levels, the antioxidant activity of hadjod extract was examined on liver protective activity2

I recently read an article that says Hadjod may be used as a diuretic. Hadjod is known for its anti-inflammatory and antioxidant properties6.

Dr. Rajeev Singh, BAMS

Also Read: Banana Leaf: Uses, Benefits, Side Effects By Dr. Smita Barode

How to Use Hadjod?

Your Ayurvedic physician will guide you for the appropriate dose and frequency of medication as per your condition. Avoid self-medication.  

Also Read: Kachnar (Bauhinia Variegata): Uses, Benefits, Nutritional Value & More!

Side Effects of Hadjod

Various studies demonstrate that hadjod extracts are safe and free of side effects at commonly used doses. The reported side effects of hadjod extract are lack of appetite, staggering, dyspnoea, and diarrhoea in a limited case4

Also Read: Akarkara (Pellitory): Uses, Benefits, Side Effects & More!

Frequently Asked Questions (FAQs)

What are the synonyms of hadjod? 

It is known as Heeressa, Hathisur, Khankho, Zarnazaru, Treebine, Banddiagra, Oongoonujaara, phet sangkhaat, san cha khuat, Veldt-grape, Adamant creeper, Asthisamadhani, Bonesetter, and Hadsanka in different regions2

What are the chemical constituents of hadjod? 

The plant contains several phytoconstituents like iridoids, stilbene derivatives, sterols, triterpenes, alkaloids, fatty acids, methyl esters, flavonoids1,2

What is the use of hadjod? 

It treats constipation, piles, tumours, blindness, loss of appetite, muscular pain, vata and kapha, epileptic fits, chronic ulcers, and bone fractures. It is also used as a digestive, anthelmintic, analgesic, laxative, stomachic, tonic aphrodisiac agent, treatment of back and spine problems, pus removal2

How to use hadjod? 

Hadjod is used in hadjod tablets, capsules, powder and drops2

Is a hadjod good for bone protection? 

Yes, hadjod has bone protective activity. Hadjod’s protective action is thought to be due to its steroidal content, which functions as phytoestrogens to prevent or minimise bone loss and suppress bone reabsorption caused by estrogen deficiency2.

References

  1. Mukherjee T, Saha N, Palbag S. Ethnopharmacology, phytochemistry and pharmacology of ayurvedic plant hadjod-Cissus quadrangularis L. Int. J. Res. Ayurveda Pharm. 2016; 7(4): 78-83. Available from: https://www.researchgate.net/publication/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L
  2. Bafna PS, Patil PH, Maru SK, Mutha RE. Cissus quadrangularis L: A comprehensive multidisciplinary review. Journal of Ethnopharmacology. 2021; 279: 114355. Available from: https://pubmed.ncbi.nlm.nih.gov/34181958/
  3. Ravi L. A review on Cissus quadrangularis L. as herbal medicine. Ind J Natural Products Resources. 2020; 11(3): 155-164. Available from: https://www.researchgate.net/publication/360411730_A_review_on_Cissus_quadrangularis_L_as_herbal_medicine
  4. A Systemic Review on the Pharmacognosy, Phytochemistry, Pharmacological and Clinical aspects of Edible stemmed vine, Cissus quadrangularis L. Am J Clin Res Rev; 2020; 4:18. Available from: https://escipub.com/Articles/AJCRR/AJCRR-2020-07-1705.pdf
  5. Shingare P. Cissus Quadrangularis–Potential Dental Biomaterial. Saudi J Oral Dent Res. 2021;6(2):97-101. doi:10.36348/sjodr.2021.v06i02.003. Available from: https://saudijournals.com/media/articles/SJODR_62_97-101_FT.pdf
  6. Sundaran J, Begum R, Vasanthi M, Kamalapathy M, Bupesh G, Sahoo U. A short review on pharmacological activity of Cissus quadrangularis. Bioinformation. 2020 Aug 31;16(8):579-585. doi: 10.6026/97320630016579. PMID: 33214745; PMCID: PMC7649020. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7649020/

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Abhayarishta: Uses, Benefits & How to Use It

Introduction

Abhayarishta is an ayurvedic formulation prepared by fermenting the decoction of the parts of the following plants fruit of Haritaki (Terminalia chebula Retz), fruit of Amalaki (Emblica officinalis Garten), fruit pulp of Kapittha (Feronia elephantum Correa), root of Indravaruni (Citrusllus colocynthetis Schrad), fruit of Vidanga (Embillia ribes Burn.F.), root of Pippali (Piper longum Linn), bark of Lodhra (Sympolocos racemosa Roxb), fruit of Maricha (Piper nigrum Linn), fruit of Kankola (Piper cubeba Linn), Guda (Jaggery) and water1. Abhayarishta is a type of Arishta formulated by anaerobically fermenting the decoctions plant parts mentioned above (kasaya) with jaggery solution in a sealed container for a specific period. This process produces ethanol that in turn works as a preservative. Abhayarishta is a similar Arishta prepared using the decoctions of the plants mentioned above2,4. The fermentation process of the Abhayarishta helps incorporate the most significant property, namely antioxidant activity, to act on anorectal diseases like piles2

Nutritional Content of Abhayarishta

The nutritional value of the significant ingredients of Abhayarishta are: 

Researchers believe that Abhayarishta might be helpful in the symptoms associated with Attention Deficit Hyperactive Disorder (ADHD) such as vomiting (emesis). Abhayarishta is believed to be anti-emetic14.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Uses of Abhayarishta

Since ancient times, Abhayarishta has been in use to treat various gastrointestinal and other various ailments related to the digestive and excretory system. It consists of a combination of various herbs which imparts a set of unique therapeutic qualities to the formulation to manage different illnesses. One of the major and vastly prevailing diseases of recent times is piles, which is mainly caused due to sedentary lifestyle and improper diet. Abhayarishta is one of the prime medications that has been found to be very beneficial in managing such diseases in the field of Ayurveda9

Some of the properties that makes Abhayarishta a better choice of remedy is: 

Benefits of Abhayarishta

1. Benefits of Abhayarishta for Constipation

constipation

2. Benefits of Abhayarishta for Piles

Haemorrhoids

3. Benefits of Abhayarishta for Vitiligo

Vitiligo

Also Read: Banyan: Benefits, Uses, Side Effects & More!

How to Use Abhayarishta?

Abhayarishta is usually mixed with equal amounts of water and taken orally as directed by your Ayurvedic physician11. Your Ayurvedic physician will prescribe you the form and dosage as per your health condition. 

Also Read: Senna: Uses, Benefits, Side Effects and More By Dr. Rajeev Singh

Frequently Asked Questions (FAQs)

Can abhayarishta be used for fistula?

Yes, Abhayarishta is used to manage the symptoms of fistula. It is used along with another set of medications to soothe the symptoms13 

Is abhayarishta used for piles? 

Yes, Abhayarishta is very beneficial to reduce the symptoms of piles by soothing the pain and inflammation in the perianal area. It can also be used to dry the pile mass and shrink it in non-bleeding piles2,9

Can I use abhayarishta as a laxative?

Abhayarishta can be used as a laxative to help manage constipation. It can induce peristaltic movement in the intestine and allow easy defecation. It also can soften the stool to reduce pain during defecation10,11

Can abhayarishta be used alone to reduce patches on the skin in vitiligo? 

No, Abhayarishta may be used along with other supportive topical applicants to help reduce the patches on the skin due to vitiligo. It helps combat the immune system’s attack on the pigment-producing melanocytes causing pale patches of skin without the pigment1

Is abhayarishta a suitable medication for acidity? 

Abhayarishta is not prescribed for acidity. 

What are the side effects of abhayarishta?

There are no documented side effects of Abhayarishta.

Can pregnant women take abhayarishta? 

Please consult do not self-administer Abhayarishta without a doctor’s prescription. Please consult your physician for case-specific recommendations. 

How much abhayarishta should I take to manage constipation?

Please follow the directions given by your physician for an appropriate course of treatment and dosage. 

Is abhayarishta always prescribed along with other different formulations? 

The prescription combination will be decided by your physician depending on your symptoms and diagnosis. Please consult your physician for further queries. 

Does abhayarishta have an expiry date?

Please read the package instructions or consult your ayurvedic pharmacist for appropriate information. 

References

  1. Clinical efficacy of Marichyadi Lepa. [cited 2022 Feb 21]; Available from: https://www.researchgate.net/publication/353682219  
  2. Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD – PubMed [Internet]. [cited 2022 Feb 21]. Available from: https://pubmed.ncbi.nlm.nih.gov/20433076/  
  3. De T, De LC. Nutrient rich foods in human diet as immunity boosters. ~ 197 ~ Journal of Pharmacognosy and Phytochemistry [Internet]. 2021 [cited 2022 Feb 22];10(3). Available from: https://www.researchgate.net/publication/351450889_Nutrient_rich_foods_in_human_diet_as_immunity_boosters  
  4. Lal B, Mishra N. Importance of Embelia ribes: An update. International Journal of Pharmaceutical Sciences and Research [Internet]. 2013 [cited 2022 Feb 22];4(10):3823. Available from:  https://www.researchgate.net/publication/265215737_Importance_of_Embelia_ribes_An_update
  5. Kavita MB, Poornima B, Mallika KJ. AMALAKI (DRIED POWDER OF EMBLICA OFFICINALIS GAERTN) AS FOOD SUPPLEMENT IN DYSLIPIDEMIA-AN ANALYTICAL STUDY. Plant Archives [Internet]. 2016 [cited 2022 Feb 24];16(1):217–25. Available from: http://plantarchives.org/PDF%2016%20-%201/217-225%20(PA3-3259).pdf
  6. Sharma M, Nagdev S, Bhurat M, Dhankani A, Jain M, Mude G. Feronia elephantum Correa: A Potential Traditional Drug. International Journal of Ayurvedic Medicine [Internet]. 2021 Sep 29 [cited 2022 Feb 25];12(3):482–4. Available from: https://www.ijam.co.in/index.php/ijam/article/view/1965  
  7. Rahimi R, Amin G, Ardekani MRS. A review on citrullus colocynthis schrad.: From traditional iranian medicine to modern phytotherapy. Journal of Alternative and Complementary Medicine [Internet]. 2012 Jun 1 [cited 2022 Feb 25];18(6):551–4. Available from: https://pubmed.ncbi.nlm.nih.gov/22784342/  
  8. Chenghe Shi, Sabiha Karim, Chunyong Wang, Mingjing Zhao, Ghulam Murtaza. A review on antidiabetic activity of Citrullus colocynthis Schrad – PubMed [Internet]. Acta Poloniae Pharmaceutica ñ Drug Research. 2014 [cited 2022 Feb 25]. Available from: https://pubmed.ncbi.nlm.nih.gov/25265814/
  9. Pardeshi K, Kadibagil V. A REVIEW ON: BHESHAJA CHIKITSA IN ARSHA. WORLD JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH [Internet]. 2017 [cited 2022 Feb 21]; Available from: https://www.researchgate.net/publication/348928648  
  10. Anupam Alman V, Ashok Alman A, Professor A, Tantra MES Ayurved Mahavidyalay S, Ratnagiri K. CLINICAL STUDY TO EVALUATE THE EFFICACY OF DHANYAK GHRITA, ABHAYARISHTA AND KANKAYAN VATI IN THE MANAGEMENT OF ARSHA. Certified Journal │ Alman et al World Journal of Pharmaceutical Research [Internet]. 2021 [cited 2022 Feb 21];10. Available from: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/930f5978f5fb655bbd8b11510be75b46.pdf  
  11. View of CLINICAL EVALUATION OF ERAND MOOLADI BASTI IN THE MANAGEMENT OF GRIDHRASI W.S.R. TO SCIATICA – A CASE STUDY [Internet]. [cited 2022 Feb 21]. Available from: http://www.ijaprs.com/index.php/ijapr/article/view/1129/895  
  12. Constipation (Vibandha) | National Health Portal of India [Internet]. [cited 2022 Feb 22]. Available from: https://www.researchgate.net/publication/361750502_A_randomized_controlled_trial_to_evaluate_the_laxative_effect_of_prescribed_diet_compared_with_Triphala_Churna_in_Vibandha_with_special_reference_to_constipation
  13. Hemorrhoids & Fistula In Ano (Arsha & Bhagandara) [Internet]. Central Council For Research In Ayurvedic Sciences, Ministry of AYUSH, Government of India. [cited 2022 Feb 22]. Available from: https://ccras.nic.in/wp-content/uploads/2024/06/Hemorrhoids.pdf
  14. Fagne MS, Thakre T, Bhaskaran JK. Role of Ayurveda in Attention Deficit Hyperactive Disorder (ADHD) – a case study. Journal of Research in Traditional Medicine. 2018;4(5-6):128–34. Available from: https://www.tmjournal.org/fulltext/140-1550831626.pdf

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