Expert Opinion: Difference Between Alzheimer and Dementia

What is Alzheimer’s Disease?

To a layman, Alzheimer’s is a disease in which the patient suffering from Alzheimer’s slowly loses his/her memory. But in medical parlance, Alzheimer’s is a progressive mental deterioration, occurring mostly in old age. This happens because of the degeneration of neurons in some parts of the brain. It is a common cause of premature senility.

How Does Dementia Typically Present?

Alzheimer’s is the most common form of dementia and typically begins with memory loss for recent events and gradual decline in various cognitive abilities, ultimately leading to interference with activities of daily living over the years. In its early stages dementia can present with:

• Subtle short-term memory changes.
• Difficulty finding the right words.
• Depression/Changes in your mood.
• Apathy.
• Difficulty completing normal (routine/familiar) tasks.
• Confusion.
• Difficulty following storylines.
• A failing sense of direction.

What is the Significance of Early Diagnosis?

The degenerative processes behind Alzheimer’s disease begin 10 or even 20 years before symptoms become evident and the condition gets diagnosed. Hence, early diagnosis is of crucial importance in addressing the symptoms effectively. To know if one suffers or is prone to suffer from Alzheimer’s, it is advantageous to be able to obtain some accurate and early diagnosis when the cognitive symptoms start:

• When dealing with reversible causes of dementia: Sometimes temporary memory loss can be caused by the use of psychoactive substances, vitamin deficiencies, trauma to the head, tumours, various metabolic diseases, hormonal dysfunction (thyroid) or infections, which can be reversed by managing the underlying cause efficiently.
• Sooner the better: Treatment of dementia is typically most effective when started early in the disease process. Although the medication can not reverse the neuronal damage by degeneration, it does slow down the process and delay further degradation, thus adding a few more months or years to live.
• Diagnoses are more accurate early in the disease process: A more precise diagnosis is possible when a complete history can be taken early in the disease process. This can happen when the person in question can answer questions about their cognitive health and report any concerns. Additionally, they should be able to observe or recall the chronological order in which the symptoms appeared. Unfortunately, an accurate diagnosis is challenging once all brain functions are compromised.
• It’s empowering: An earlier diagnosis can be empowering as the person can participate in their own financial, legal and other long-term life care plans. They can also alert their family members about their condition.
• They can focus on what’s important to them: Priorities in life change especially when such a severe diagnosis comes up. Therefore, early diagnosis, helps the person rethink and re-prioritize their life. Who they want to be with, how they wish to spend their time, what matters, life goals from here on, etc. They may choose to record their important moments, complete pending tasks, make new memories and so on.
• One can make the best choices: With early diagnosis, one can make better decisions which they may have overlooked due to ignorance like moving far away from family or breaking up with friends or getting into draining financial commitments.
• One can use the resources available: Individuals diagnosed early in the disease process can take advantage of available health services and early-stage support groups and learn tips and strategies to better manage and cope with the symptoms of the disease.
• It will help the family: An early diagnosis gives families more opportunity to learn about the disease, develop realistic expectations and plan for their future together – which can result in reduced stress/anxiety and feelings of burden and regret later in the disease process.
• It will help the person too: Early diagnosis allows the person and family to attribute cognitive changes to the disease rather than to personal failings – preserving the person’s ego throughout the disease process.

What is the Recent Research Update on Signs to Predict the Onset of Alzheimer’s?

In a recent study published in The American Journal of Psychiatry (Haridy et 2018), it was found that increasing symptoms of anxiety could be an early indicator of Alzheimer’s, thus allowing health professionals better targets for early interventions to treat the condition before it causes too much irreversible neurological damage.

Depression has often been a common denominator in the preclinical phase of those diagnosed later with dementia. When specific symptoms from the same were assessed in correlation with the cellular pathology of dementia, the researchers found a stronger association of the pathology (beta-amyloid levels in the brain) with the person’s preclinical state anxiety. However, this study did not comment upon its association with the subsequent onset of Alzheimer’s disease, thus warranting further long-term study to ascertain such connection, if present. This research being in its preliminary stages also awaits application on pragmatic levels.

What is Trait and State Anxiety?

State anxiety describes the experience of unpleasant feelings when confronted with specific situations, demands or an object or event. Typically anxiety arises when the person makes a mental assessment of some threat. When the perceived threatening object or situation goes away, the person no longer experiences the anxiety, thus making it a temporary condition.

Like state anxiety, trait anxiety arises in response to a perceived threat, but it differs in its intensity, duration and the range of situations in which it occurs. Trait anxiety refers to the variation in people’s tendency to experience state anxiety in response to an anticipated threat. People with a high level of trait anxiety experience relatively more intense degrees of state anxiety and to a broader range of situations. Thus, trait anxiety describes a personality characteristic rather than a temporary feeling.

What is a ‘Catastrophic Reaction’?

A catastrophic reaction is an excessive reaction by a person, to something that may seem otherwise inconsequential to others. Quite often, a person with dementia simply may not be feeling well or might be feeling rushed and confused during early-stage symptoms (when they notice/ experience their new-found inefficiency) or could be triggered by some distant memory or some complication in communication. It is important for caregivers and family members to be sensitive to the emotional needs of the ones suffering from this experience and respond to them with empathy, patience and reassurance.

What is the Role of the Caregivers?

In the early stage of Alzheimer’s, most people function independently.  He or she may still drive, take part in social activities, volunteer and even continue to work. As a caregiver/partner, it is important to provide adequate support and companionship to the person and help him/her plan.

It is a new and unfamiliar role to play and might make one unsure of where to go for information or anxious about what to expect as the disease progresses and wonder whether one would be able to support the loved one living with dementia. In such cases, it is recommended to communicate with your nearest mental health facility or professional/s and seek medical guidance and support.

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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