Sitopaladi Churna: Uses, Benefits, Side Effects & More!
Introduction
Sitopaladi churna is an Ayurvedic preparation used for digestive problems and various respiratory issues. Sitopaladi churna helps balance the kapha and pitta doshas. It is made from ingredients like cardamom (elaichi), cinnamon (twak), bamboo (vanshlochan), long pepper (pippali), and sugar candy (khandasharkara).
All these ingredients are cleaned and crushed to obtain a fine powder. The powder is then filtered to remove any coarse particles. Sitopaladi churna has a madhura (sweet) and katu rasa (bitter taste). This churna may help to eliminate ama (harmful toxins) out of the body1.
Ingredients of Sitopaladi Churna
The quantity of ingredients in sitopaladi churna is2:
Khandasharkara: 40 grams
Ela: 10 grams
Twak: 5 grams
Vanshlochan: 30 grams
Pippali: 15 grams
The inorganic elements present in sitopaladi churna are calcium, sodium, potassium, iron, magnesium, sulfate, phosphate, carbonate, nitrate, and chloride. The organic elements present in sitopaladi churna are carbohydrates, proteins, amino acids, steroids, flavonoids, alkaloids, tannins, and phenolic compounds2.
Did you know?
Sitopaladi churna is an ayurvedic formulation used in the treatment of allergy and respiratory diseases. source: PubMed
Sitopaladi churna has mast cell stabilizing potential, making it effective in treating allergic disorders. source: PubMed
Sitopaladi churna can be used as an effective treatment for cold, cough, bronchitis, pneumonia, and tuberculosis. source: PubMed
SPC can be used to treat intercostal neuralgia, viral respiratory infections, and digestive impairments. source: PubMed
Properties of Sitopaladi Churna
The various beneficial properties of sitopaladi churna may include3:
It may have anti-inflammatory properties
It may show expectorant (clear mucous from the airways) activity
It may show anti-tussive (cough-suppressing) potential
It may have Immunomodulatory property
It may be an antioxidant
It may be used as a tonic
It may be a potential detoxifier
It may show carminative (relieving flatulence) properties
I would suggest sitopaladi churna in allergic disorders. There’s an important chemical called piperine found in the sitopaladi formulation. Owing to its capacity to stabilise mast cells, sitopaladi churna may be a justified treatment for allergic disorders13.
Sitopaladi churna contains expectorant properties that may help expel mucous from the airways. According to Ayurveda, cough is grouped into five categories: vata (dry cough that produces some mucous), pitta (cough that produces moderate and sticky mucous), ksataja (cough that occurs due to chest injury), and ksaya (cough that occurs due to tuberculosis-like chronic diseases).
Sitopaladi churna may be an helpful for all these types of coughs. It may be taken with honey, ghee, water, or other herbal medications. Sitopaladi churna may help with cough by acting on the central nervous system3. However these effects of sitopaladi churna may need further studies.
2. Potential Uses of Sitopaladi Churna for Digestive Health
Sitopaladi churna contains deepan (appetizing) and pachan (digestive) properties that may help to enhance digestion. It also contains carminative properties that might be helpful in gas accumulation and bloating3. The studies seem insufficient to validate these claims, therfore consult an ayurvedic physician before taking sitopaladi churna for its effect on digestion.
3. Potential Uses of Sitopaladi Churna for Allergies
The immune system in people with allergies responds to allergens like dust, pollen, dander, etc. by releasing a substance called histamine. Due to this, the person might experience symptoms like watery eyes or a running nose. Sitopaladi churna contains antihistaminic properties and might protect you from allergies4. You must visit a doctor immediately for relief in case of any allergic reactions.
4. Potential Uses of Sitopaladi Churna for Diabetes
The digestive enzyme amylase has to break down complex carbohydrates before they are absorbed. Carbohydrates are broken down into simple sugars and enter the blood leading to an increase in blood sugar levels. Sitopaladi churna may show α-amylase inhibition properties. This property might help prevent the body from absorbing these carbohydrates and prevents a spike in blood sugar after meals3. Diabetes is a major health condition and requires appropriate diagnosis and treatment from a professional doctor. Therefore, human trials of Sitopaladi churna are necessary to provide its potential usage for managing blood sugar levels in humans.
5. Potential Uses of Sitopaladi Churna for Anaemia
Anaemia can lead to shortness of breath, dizziness, tiredness, and irritability. The most common cause of anaemia is iron deficiency. Sitopaladi churna may help increase iron absorption by the body and thus helps in nutritional anaemia3. Further studies are needed to establish the claim of effect of sitopaladi churna for anaemia.
6. Potential Uses of Sitopaladi Churna for Migraine
Sitopaladi churna combined with other herbal medications, along with modified diet and lifestyle modifications like 8 hours of proper sleep, 30-60 min of morning or evening walk, and abstaining from smoking and drinking proved to be effective in the management of migraine5. However these claims need further studies, you must consult a doctor for proper advice on migraines.
7. Potential Uses of Sitopaladi Churna for Cough and Respiratory Problems
Sitopaladi churna may be helpful in conditions like fever related to flu, cold, chest congestion, pneumonia, tuberculosis, bronchitis, and other respiratory illnesses. This herbal preparation may help control respiratory infections due to its anti-inflammatory and antioxidant properties2. However, respiratory conditions may need medical supervision and diagnosis. Consult a qualified doctor for treatment of any respiratory condition.
8. Potential Uses of Sitopaladi Churna for Vocal Cord Nodules
Vocal nodules occur due to abuse or misuse of the vocal cords. Some professions require high-volume speech. This might lead to the formation of vocal nodules. Sitopaladi churna along with other herbal formulations may be used for managing vocal nodules. Studies show that it may give some relief from the symptoms and the person can regain their original voice6. But consult a doctor for advice before consuming sitopaladi churna on your own.
Though there are studies showing the benefits of sitopaladi churna in various conditions, these are insufficient. There is a need for further studies to establish the true extent of the benefits of sitopaladi churna on human health. Furthermore, every person may respond differently to these herbs. Therefore, it is important to consult a doctor before using sitopaladi churna for any medical condition.
In my opinion, when we combine the herbal product from Bambusa arundinacea found in sitopaldi churna with other medicines, it might create a powerful anti-inflammatory drug. It’s like a dream team for treating chronic inflammatory conditions like rheumatoid arthritis with peptic ulcers, which are quite common. This combination may also offer hope for long-term treatment and relief in the said conditions14.
Sitopaladi churna can either be taken with honey, water or ghee10. One should always take the advice of an Ayurvedic physician before having sitopaladi churna. In addition, we recommend you do not replace or discontinue your ongoing medications with any ayurvedic or herbal preparations without seeking the medical advice of a qualified doctor. They will guide you with the best form and dosage in which the herb can be used per your health condition.
There is not sufficient evidence for sideeffects of Sitopaladi churna and it may be safe when used by children and pregnant women. It is essential to consult an Ayurvedic physician and take only take prescribed doses3.
Sitopaladi churna can be taken during pregnancy and lactation under the supervision of an Ayurvedic physician.
It is not recommended to take sitopaladi churna on an empty stomach, particularly for those who are susceptible to gastric problems3.
Due to the presence of sugar candy in sitopaladi churna, it is important to consult a doctor before taking this medicine if you have high blood sugar
Sitopaladi churna when exposed to various environmental factors might result in degradation of the ingredients and promote microbial growth. This can affect the therapeutic value of sitopaladi churna. Hence, this formulation has to be stored in an air-tight container1.
Having sitopaladi churna in moderation might be safe. However, one must follow general precautions and doctors advice.
Due to its kapha and vata dosha balancing qualities, sitopaladi churna might be helpful in the management of asthma symptoms. It helps to breathe easily by clearing the air pathways7,8. Every person may respond differently to these herbs. Therefore, it is important to consult a doctor before using sitopaladi churna for any medical condition.
Can sitopaladi churna be used for intercostal neuralgia?
Intercostal neuralgia is nerve pain right under you’re the ribs. There can be pain in the chest and upper back region. Sitopaladi churna may be helpful in the management of intercostal neuralgia9. It is however, important to consult a doctor before using sitopaladi churna for any medical condition.
How is sitopaladi churna prepared?
The ingredients of sitopaladi churna are taken separately, crushed well to form a powder, and filtered through a clean cotton cloth. The ingredients are then mixed together to form a uniform mixture and then stored in an air-tight container10.
Can sitopaladi churna be used in covid infections?
According to a case report Sitopaladi churna might be helpful in post-covid lung complications due to its affinity towards the respiratory system11. This may be followed under supervision and guidance of a qualified doctor.
What are the other names of sitopaladi churna?
Sitopaladi churna is also known by the names- sitopaladi choorna, sitopaladi choornam, sitopaladi chooran, etc12.
Can Sitopaladi Churna be used for sore throat?
Yes, Sitopaladi Churna’s soothing properties can help ease the discomfort of a sore throat by reducing inflammation and providing relief from irritation. Mixing it with honey and consuming it may be beneficial for a sore throat.
How to take Sitopaladi Churna?
Sitopaladi Churna is typically taken orally with honey or warm water. The dosage and frequency may vary depending on the individual’s age, condition and the Ayurvedic practitioner’s recommendation.
Is Sitopaladi Churna suitable for individuals with diabetes?
Sitopaladi Churna contains sugar candy, which may impact blood sugar levels. Individuals with diabetes should consult their healthcare provider or an Ayurvedic practitioner before using it and consider alternatives without sugar candy.
Does Sitopaladi Churna have a pleasant taste?
Sitopaladi Churna generally has a pleasant taste due to the combination of sweet and aromatic herbs like sugar candy and cardamom. Mixing it with honey or warm water can enhance its taste.
Can Sitopaladi Churna be taken on an empty stomach?
Ayurvedic practitioners often recommend taking Sitopaladi Churna after meals for better absorption and to avoid any potential discomfort on an empty stomach.
Nikunj D patel, Prajesh N Prajapati, Niranjan S kanaki; Quality assessment of sitopaladi churna using high performance liquid chromatography coupled with multivariate analysis. Journal of chromatographic science. 2020 Nov-Dec 58(10): 961-968 Available from: https://academic.oup.com/chromsci/article/58/10/961/5917699
Sai Chinmayee T, Geetha B. Markande, Subrahmanya Padyana; Pharmaceutico analytical study of sitopaladi choorna and its lehya. International Ayurvedic medical journal. 2020 May. Available from: http://www.iamj.in/prposts/2020/images/upload/02281_2284.pdf
Makhija IK, Shreedhara CS, Ram HN. Mast cell stabilization potential of Sitopaladi churna: An ayurvedic formulation. Pharmacognosy Res. 2013 Oct;5(4):306-8. doi: 10.4103/0974-8490.118824. PMID: 24174826; PMCID: PMC3807997. Available from:https://pmc.ncbi.nlm.nih.gov/articles/PMC3807997/
Muniappan M, Sundararaj T. Antiinflammatory and antiulcer activities of Bambusa arundinacea. J Ethnopharmacol. 2003 Oct;88(2-3):161-7. doi: 10.1016/s0378-8741(03)00183-1. PMID: 12963137.Available from: https://pubmed.ncbi.nlm.nih.gov/12963137/
Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.
Links and product recommendations in the informationprovided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.
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Triphala: Uses, Benefits, Side Effects & More!
Introduction
Three medicinal herbs make up Triphala (in Sanskrit, “tri” means “three” and “phala” means “fruits”). It is an antioxidant-rich herbal preparation described as a Rasayana (rejuvenator) medicine by Ayurvedic practitioners. Combining the three fruits is said to be responsible for Triphala’s numerous health benefits1.
Triphala is made from the dried fruits of:
Terminalia chebula (black myrobalan)
Terminaliabellerica (bastard myrobalan)
Phyllantus emblica (emblic myrobalan or Indian gooseberry)
Chemical Composition of Triphala
The spring-harvested fruits of Terminalia chebula are high in tannins such as gallic acid, ellagic acid, chebulic acid, chebulinic acid, chebulagic acid, neochebulinic acid, corilagin, terchebin, punicalagin, terfavin, flavonoids (rutins, luteolin and quercetin), starches, amino acids (glutamic acid, aspartic acid, lysine, arginine and proline), β-sitosterol, succinic acid, fructose and fatty acids2.
The fruits of Terminalia bellerica consist of proteins and oils that include omega-3 and omega-6 fatty acids (linoleic acid). Because of its high fatty acid content, this plant can impact cholesterol levels, increasing high-density lipoprotein levels (good cholesterol) while decreasing low-density lipoprotein levels (bad cholesterol), making it effective in treating coronary artery disease.
Phyllanthus emblica (amla) fruits are high in ascorbic acid, i.e. vitamin C2.The high density of tannins may contribute to the overall bitterness of amla. These fruits also include punicafolin and phyllanemblinin A, phyllemblin, and other polyphenols such as gallic acid, ellagic acid, flavonoids and kaempferol2.
Based on my experience, I have come across evidence suggesting that Amalaki, which is a component of Triphala, may possess properties to manage diseases of the sense organs and enhance memory. It is believed that the active compounds present in Amalaki exert beneficial effects on the central nervous system, potentially improving sensory function and memory.
Triphala is described as a tridoshic Rasayana in Ayurveda, capable of balancing and rejuvenating the three doshas that regulate human life: Vata, Pitta and Kapha. It is widely used in several disease conditions owing to its following properties1,3:
Laxative
Anti-inflammatory
Antiviral
Blood purifying
Analgesic
Anti-arthritic
Hypoglycemic
Anti-ageing
Antibacterial
Triphala is used to treat fatigue, oxidative stress, and infectious disorders like tuberculosis, pneumonia, AIDS and periodontal disease, among others. It’s also used for headaches, dyspepsia, ascites and leukorrhea3.
In my experience, I have observed that Triphala, a herbal formulation, may have the ability to increase the number of red blood cells and improve haemoglobin content in the body, making it potentially beneficial for managing anaemia. The active compounds in Triphala are believed to stimulate the production of red blood cells, leading to an increase in haemoglobin levels and overall improvement in anaemic conditions.
Triphala and its components have demonstrated potent antimicrobial properties against a variety of microorganisms.
Triphala churna has proven action against the human immunodeficiency virus (HIV).
Triphala churna and Triphala mashi have shown antibacterial properties against a variety of bacteria, like E. coli and S. aureus1.
2. Promotes Dental Health
Triphala reduced levels of chemicals which are implicated in the destruction of tissue during periodontitis (inflammation of tissues surrounding teeth).
Triphala mouthwash was tested clinically and found to be as effective as chlorhexidine in lowering plaque scores and inhibiting Lactobacillus bacteria microbial levels1. More studies are needed to better understand these effects.
3. Helps Manage Stress
Triphala supplementation has been shown to alleviate stress.
This should be studied further to under its role in stress management.
4. Supports Joint Health
Triphala prevented monosodium urate crystal-induced arthritis in mice (gouty arthritis) by reducing various chemicals involved in the worsening of joint health.
It might have potential use in the treatment of gout in humans, however, more studies are needed for the same1.
5. Aids Digestion
Castor oil-induced diarrhoea was prevented by extracts of Triphala churna powder and Triphala mashi.
The extracts had a strong antidiarrhoeal effect, as demonstrated by increased first defecation time, cumulative faecal weight, intestinal transit time, improved stool volume, stool frequency, stool consistency, decreased mucus level in stool, and flatulence1.
More studies are needed to understand the exact indication of Triphala in managing diarrhoea.
6. Supports Liver Function
In mice, Triphala was found to be beneficial against acetaminophen-induced liver damage but with less efficacy than silymarin.
Triphala lowered the levels of proinflammatory cytokines and lipid peroxides while also restoring the levels of many antioxidant enzymes and reducing liver damage, as seen by lower liver enzyme values1.
People with liver disease should consult a doctor before consuming Triphala or any other Ayurvedic or herbal supplement.
7. May Help Manage Diabetes
Animal studies have demonstrated that giving the same amount of Triphala and its separate ingredients to normal and alloxan-induced diabetic rats lowered serum glucose levels.
Thus, with more research, Triphala might be useful in treating diabetes in humans1.
8. May Support Weight Management
After the treatment of mice with Triphala in an anti-obesity study, their body weight was observed to be lower when compared to control animals.
Gallic acid is a phenolic molecule found in Triphala that was chosen as the bioactive marker because of its anti-obesity activity3.
9. Promotes Heart Health
Triphala has been found to have a lipid-lowering impact on rats, with significant reductions in total cholesterol, low-density lipoprotein, very low-density lipoprotein, and free fatty acid, indicating hypocholesteremic condition.
These properties make it cardio-protective.
10. Supports Skin Healing
The topical application of Triphala extract aided wound healing in rats infected with a variety of bacteria, according to a study6.
Experiments revealed that the Triphala ointment reduced bacterial count and promoted wound closure by increasing collagen, hexosamine, and uronic acid levels1.
11. Radioprotective Properties
Triphala has been proven in preclinical trials to have radioprotective properties when taken orally.
The most effective action of Triphala was seen when given before irradiation, lowering DNA damage in both white blood cells and spleen cells, the normalising activity of certain enzymes like xanthine oxidase and super oxidase dismutase found in the intestine.
This indicates that the observed effects were mediated through the inhibition of oxidative damage in the cells and organs1.
12. Boosts Immunity
Triphala has been shown to have potent immunomodulatory properties in a variety of animal models.
Flavonoids, tannins, alkaloids, glycosides, saponins, and phenolic substances are thought to have immunomodulatory properties.
Triphala treatment increased antioxidant activity and lowered corticosterone levels in animals exposed to noise stress, according to research7.
13. Rich in Antioxidants
According to research9, taking Triphala boosts the activity of antioxidant enzymes, which may have resulted in a considerable reduction in stomach cancers in mice.
When rats were given Triphala and were subjected to noise stress, similar results were reported.
Such findings point to Triphala’s ability to act as an antioxidant and to protect against a variety of stressors and illnesses1.
14. Supports Eye Health
Triphala was found to be beneficial in preventing and reducing selenite-induced cataract formation, according to a study8.
In animal trials, Triphala restored antioxidant enzyme levels, resulting in a reduction in nuclear cataracts. As per Ayurveda, Triphala can also help reduce the risk of blindness and near-sightedness in some cases1.
15. Potential Anti-Cancer Properties
Triphala caused an increase in intracellular reactive oxygen species, which may be beneficial in supporting cancer treatment in some cases3.
Triphala or any herbal supplements should not be given to cancer patients who are under treatment unless advised by a doctor. There are chances of severe drug interactions in patients receiving cancer treatment; hence self medication, even with herbal or ayurvedic medicines, should be avoided.
16. Anti-Ageing Benefits
On human skin cells, Triphala extract has shown strong antiaging effect.
It stimulates collagen-1 and elastin-synthesizing genes and antioxidant genes responsible for cellular antioxidants in human skin cells.
Due to the presence of protective phytochemicals, it may also suppress melanin synthesis and hyperpigmentation4.
Over the years, I have observed that Triphala, a herbal formulation, might have growth inhibitory activities against certain bacterial strains commonly found in HIV-infected patients. Studies have indicated that the aqueous and ethanolic extracts of Triphala, as well as its individual plant components, have shown potential antibacterial effects against these bacterial isolates.
Haritaki, bibitaki, and amlaki are powdered to make Triphala churna (powder). As per research, it is advisable to take it with ghee, honey, or milk1.
2. Triphala Kwatha (Decoction):
It is made by combining the powder with water and boiling it. The decoction is then filtered through a clean cloth, and the filtrate can be used to treat skin conditions like erysipelas, eruptions, scrotal enlargement, colic pain, worm infestation, and urinary diseases. It is applied directly to open wounds and eyes, as well as gargled during pharyngitis1.
3. Triphala Taila (Oil):
It is made by boiling Triphala powder with oil. It is used as a gargle, snuff, an enema, and orally to treat obesity and itching1.
4. Triphala Masi (Ash):
It’s made by heating Triphala powder for a long time at a low temperature in a controlled setting. Mashi/Masi is an intermediate product containing organic and inorganic ingredients. The mashi is black and has a high carbon and oxide content. Triphala Mashi, when mixed with honey, can be used to treat soft chancres and wounds1.
5. Triphala Gritha (in ghee or clarified butter):
It is made by cooking the paste of Triphala, trikatu (a herbal compound of Indian Long Pepper (Piper longum), Black Pepper (Piper nigrum), and Ginger (Zingiber officinale) in ghee and milk, as well as grapes (Vitis vinifera), Yestamadhu (Glycyrrhiza glabra), Kutki (Picrorhiza korroa), and cardamom (Elettaria cardamom). It is frequently used to treat eye conditions like conjunctivitis, blindness, and cataracts. Triphala gritha is also used to treat jaundice, leucorrhoea, tumours, greying, and hair loss1.
Triphala is an ayurvedic herbal formulation made up of dried fruits from three different plants: Terminalia chebula (black myrobalan), Terminalia bellerica (bastard myrobalan), and Phyllantus emblica (emblic myrobalan)2.
How to use Triphala churna?
It is suggested that Triphala churna can be taken with ghee, honey, or milk1.
The Triphala gritha is made by boiling the Triphala paste in ghee and milk. It is frequently used to treat eye conditions like conjunctivitis, blindness, and cataracts1.
What is the use of Triphala churna?
Triphala churna has analgesic, antibacterial, anti-arthritic, hypoglycemic, antiaging, antiviral and anti-inflammatory properties. It helps with headaches, dyspepsia, fatigue, oxidative stress reduction, and infectious disorders like tuberculosis and periodontal disease3. It is also used for eye problems such as infections, blindness, myopia, and cataractogenesis1.
Is Triphala good for the liver?
Yes, Triphala is good for the liver as it reduces pro-inflammatory chemicals, restores the levels of antioxidant enzymes, and reduces liver damage, as seen by lower serum enzyme values1.
How is Triphala churna made?
It is made by grinding haritaki, bibitaki, and amlaki1.
What are the Triphala fruits?
Triphala is an ayurvedic herbal formulation made up of dried fruits from three different plants: Terminalia chebula (black myrobalan), Terminalia bellerica (bastard myrobalan), and Phyllantus emblica (emblic myrobalan or Indian gooseberry)2.
How does Triphala work for eyesight?
Triphala restores antioxidant enzyme levels in experimental animals, resulting in an 80% reduction in cataract formation1. Thus, it might be helpful in improving eyesight in humans, but more studies are needed to prove the same.
Is Triphala good for hair?
Yes, Triphala is good for hair. It is considered to help with hair greying and hair loss1.
References
Baliga MS, Meera S, Mathai B, Rai MP, Pawar V, Palatty PL. Scientific validation of the ethnomedicinal properties of the Ayurvedic drug Triphala: a review. Chin J Inter Med. 2012; 18(12): 946-954. https://sci-hub.st/10.1007/s11655-012-1299-x
Tarasiuk A, Mosińska P, Fichna J. Triphala: current applications and new perspectives on the treatment of functional gastrointestinal disorders. Chin Med. 2018; 13(1): 39. https://sci-hub.st/10.1186/s13020-018-0197-6
Peterson CT, Denniston K, Chopra D. Therapeutic uses of Triphala in Ayurvedic medicine. J Altern Complement Med. 2017 Aug;23(8):607-614. doi:10.1089/acm.2017.0083. PMID: 28696777; PMCID: PMC5567597. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567597/
Gupta SK, Kalaiselvan V, Srivastava S, Agrawal SS, Saxena R. Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies. J Ayurveda Integr Med. 2010 Oct;1(4):280-6. doi:10.4103/0975-9476.74425. PMID: 21731375; PMCID: PMC3117320. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117320/
Prasad S, Srivastava SK. Oxidative stress and cancer: Chemopreventive and therapeutic role of Triphala. Antioxidants (Basel). 2020 Jan 13;9(1):72. doi:10.3390/antiox9010072. PMID: 31941067; PMCID: PMC7022920. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022920/
Disclaimer:The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.
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Chitrakadi Vati: Uses, Benefits, Side Effects & More!
Introduction
Chitrakadi vati is well recognised as an Ayurvedic preparation1. It is a polyherbal formulation containing nine ingredients of herbal origin: Chitraka (Plumbago zeylanica), maricha (Piper nigrum), pippali (Piper longum fruit), pippalimoola (Piper longum root), Chavya (Piper chaba), ginger (Zingiber officinale), hing (Ferula foetida/Ferula asafoetida), ajmoda (Apium leptophyllum), yava ksara (Hordeum vulgare) and panchalavana (Samudra, Sauvarchala, Saindhava, Vida, Audbhida)2.
Uses of Chitrakadi Vati
The uses of Chitrakadi Vati are as follows:
It is commonly used to manage irritable bowel syndrome, abdominal tumours, rheumatoid arthritis, and appetite loss.
It is also used as a digestive tonic and carminative. Chitrak stimulates digestion and appetite and aids in dealing with leprosy, fever, oedema, and scabies1,2.
Long pepper is an anti-asthmatic, laxative, anti-infective agent in urinary tract infections, aphrodisiac, carminative, and analgesic1.
Black pepper is used as a diuretic and analgesic and for managing constipation, piles, and colic1.
Ginger is used to deal with heart problems and acts as a carminative1.
According to Ayurveda, Chitrakadi vati might be useful in decreasing mouth dryness caused due to increased levels of vatta and pitta levels and decreased kapha levels in the body. Chitrakadi vati might stimulate saliva secretion13.
1. Benefits of Chitrakadi Vati Due to Laxative Activity
The laxative efficacy of extract of Chitrakadi vati at various doses was studied1 in rats.
The extract of Chitrakadi vati showed significant laxative action by increasing the stool output weight.
The presence of long pepper and black pepper in Chitrakadi vati contribute to the laxative properties.
2. Benefits of Chitrakadi Vati for Ovulation
According to a study3, Chitrakadi vati was one of the best medications for follicular rupturing tests.
As a result, Chitrakadi vati was selected as a replacement for the human chorionic gonadotropin hormone for follicular rupture.
3. Benefits of Chitrakadi Vati for Liver
Consumption of Chitrakadi gutika formulation (tablet of various herbs) and buttermilk was found to be effective in dealing with non-alcoholic fatty liver disease by reversing the fatty infiltration of the liver4.
The liver-protective efficacy of extract of Chitraka roots was investigated in rats.
The extract administration to rats dramatically reduced the serum marker levels, demonstrating that extract has a liver protective impact in restoring the hepatocytes’ normal function5.
4. Benefits of Chitrakadi Vati for Managing Inflammation
The anti-inflammatory activities of Chitraka leaf extract were studied5 in experimental animal models.
The extract exhibits anti-inflammatory activity by reducing the prostaglandin synthesis and release.
5. Benefits of Chitrakadi Vati for Managing Diabetes
The antidiabetic effect of Chitraka roots extract was studied in rats.
The root extract exhibited antidiabetic activity by increasing the hepatic hexokinase activity while decreasing serum acid phosphatase, hepatic glucose-6-phosphate, alkaline phosphatase and lactate dehydrogenase levels.
The active constituent of the extract, plumbagin, significantly reduced the blood glucose levels in diabetic rats5.
6. Benefits of Chitrakadi Vati for Digestion
Dietary maricha stimulates pancreatic enzymes that improve digestion and reduce food transit time in the gastrointestinal tract.
It also increases saliva production and gastric secretions and activates the salivary amylase enzyme.
Maricha or piperine present in Chitrakadi vati on oral administration stimulates the release of bile acids from the liver, which are important in the digestion and absorption of lipids6.
7. Benefits of Chitrakadi Vati for Managing Cholesterol
Maricha inhibits cholesterol absorption while increasing cholesterol transporter protein translocation.
It also improves digestion by assisting in the breakdown of bigger fat molecules into more easily digestible simple molecules and preventing fat storage in the body6.
8. Benefits of Chitrakadi Vati Due to Anti-diarrhoeal Activity
The antidiarrhoeal effects of maricha extract were studied6 in rats at various doses.
The extract was shown to have considerable anti-diarrhoeal, anti-motility, and anti-secretory activity due to the presence of alkaloids in maricha.
9. Benefits of Chitrakadi Vati in Managing Blood Clotting
The effect of ginger extract on platelet thromboxane-B2 and prostaglandin-E2 synthesis was studied in rats.
Oral administration of ginger at high doses is significantly effective in reducing serum prostaglandin-E2 and thromboxane-B2 levels.
According to the findings, ginger can be employed as an anti-thrombotic and anti-inflammatory agent7.
10. Benefits of Chitrakadi Vati for Gastrointestinal Tract
Traditional medicine has long employed the powdered rhizome of ginger to relieve the symptoms of gastrointestinal tract ailments.
According to a study7 in mice, the extract of ginger and its components improved the gastrointestinal emptying of the charcoal meal.
In humans, ginger has been shown to help prevent postoperative nausea and vomiting while not affecting stomach emptying.
11. Benefits of Chitrakadi Vati as an Antioxidant
Several studies have revealed that ginger has potent antioxidant effects.
The antioxidant effect of ginger has been proposed as one of the key probable reasons for the plant’s protective properties against radiation toxicity and lethality, as well as a variety of poisonous substances and potential as an anti-ulcer drug7.
The extracts of the Asafoetida plant showed antioxidant activity in experimental animals.
Results of the study showed a reduction of lipid peroxidation levels in the liver of rats8.
12. Benefits of Chitrakadi Vati for Managing Obesity
The effects of F. asafoetida on weight gain and fat build-up in diabetic patients were researched.
It was shown to reduce body weight, abnormal fat, and adipocyte cell size.
As a result, it will be regarded a viable therapy option for diabetes-induced obesity8.
13. Benefits of Chitrakadi Vati Due to Immunomodulatory Activity
The extracts of chavya considerably boost lymphocyte proliferation, implying an immunomodulatory action, mainly through lymphocyte proliferation and natural killer cell activity activation9.
In Ayurveda, Chitrakadi vati might help in reducing oedema in the legs and hands (extremities) caused due to ama dosha13.
Some side effects are observed due to the following constituents of Chitrakadi vati:
Chitraka: Excessive use of the chitraka plant has toxic effects. Irritation burning of the tongue, throat, stomach and other body regions can be seen. It can also cause nausea, vomiting, dysuria, diarrhoea, burning sensation while urinating, a weak pulse, wrinkled skin, and cold skin11.
Ginger: It may cause heartburn, mild diarrhoea, gastric irritation and allergy7.
Hing: Its extracts have been investigated and proven safe for everyday usage. Large doses of asafoetida can cause mouth swelling, digestive problems such as flatulence and diarrhoea, nervousness, and headaches8.
Generally, according to Ayurveda, ama and vatta doshas can create joint pain. In such cases, Chitrakadi vati might be useful in reducing joint pain13.
In pregnancy, the utilisation of chitraka plants can irritate pelvic organs and ultimately cause abortion11.
The gum of closely related species of Hing may irritate the skin and stomach, resulting in dermatosis12.
Because it affects the menstrual cycle and is an abortifacient, Hing should not be used during pregnancy or lactation8,12.
Foetal haemoglobin is oxidised with asafoetida use, whereas adult haemoglobin is not. Children should not be given this medication since it may cause methaemoglobinemia12.
It is commonly used to manage irritable bowel syndrome, rheumatoid arthritis, and appetite loss. It is also used as a digestive tonic and carminative. Chitrak stimulates digestion and appetite and aids to deal with leprosy, fever, oedema, and scabies1,2.
How to use chitrakadi vati?
It is used in the form of Chitrakadi vati extract and Chitrakadi dutika (pills)1,10.
Is chitrakadi vati good for liver?
Yes, it is good for the liver. The consumption of Chitrakadi gutika and buttermilk was found to be effective in managing the non-alcoholic fatty liver disease by returning the fatty infiltration of the liver to a normal level4.
References
Kumar A, Deepa L, Lakshman K, Satish KV, Chandra Shekar KB, Narayan Swamy VB, et al. Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats. Pharmacologyonline [Internet]. 2007 [cited 2022 Feb 28];1:420-3. Available from: https://pharmacologyonline.silae.it/files/archives/2007/vol1/44_Kumar.pdf
Khanvilkar V, Patil L, Kadam V. Standardization of Chitrakadi Vati: An Ayurvedic Polyherbal Formulation. Int J Pharm Sci Drug Res [Internet]. 2014 [cited 2022 Feb 28];6(4):303-9. Available from: https://www.ijpsdr.com/index.php/ijpsdr/article/view/359/323
Shukla K, Karunagoda K, Sata N, Pandya MA. Evaluation of the role of Chitrakadi Vati in the management of Bandhyatva w.s.r to anovulation (as a consequence of unruptured follicle). AYU [Internet]. 2009 [cited 2022 Feb 28];30(4):392-6. Available from: https://www.ayujournal.org/temp/Ayu304392-5572047_152840.pdf
Chandran A, Mahadevan L, Nisha MG. Clinical Efficacy of Chitrakadi Gutika in Non Alcoholic Fatty Liver Disease-A Case Study. Int J AYUSH Case Reports [Internet]. 2021 [cited 2022 Feb28];5(4):237-41. Available from: https://www.ijacare.in/index.php/ijacare/article/view/250/203
Saleem A, Naureen I, Naeem M, Tasleem G, Ahmed H, Farooq U. Therapeutic Role of Piper Nigrum L (Black Pepper) and Pharmacological Activities. Sch Int J Biochem [Internet]. 2022 [cited 2022 Feb 28];5(1):15-21. Available from: https://saudijournals.com/media/articles/SIJB_51_15-21.pdd
Ali BH, Blunden G, Tanira MO, Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chem Toxicol [Internet]. 2008 [cited 2022 Feb 28];46(2):409-20. Available from: https://sci-hub.st/10.1016/j.fct.2007.09.085
Amalraj A, Gopi S. Biological activities and medicinal properties of Asafoetida: A review. J Trad Complementary Med [Internet]. 2017 [cited 2022 Feb 28];7(3):347-59. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506628/
) Islam MT, Hasan J, Snigdha HS, Ali ES, Sharifi-Rad J, Martorell M, et al. Chemical profile, traditional uses, and biological activities of Piper chaba Hunter: A review. J Ethnopharmacol [Internet]. 2020 [cited 2022 Feb 28];257:112853. Available from: https://pubmed.ncbi.nlm.nih.gov/32283191/
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